메뉴 건너뛰기




Volumn 19, Issue 2, 1997, Pages 93-101

Biology and genetics of human neuroblastomas

Author keywords

1p36; Gene amplification; MYCN oncogene; Nerve growth factor (NGF); Neuroblastoma; Suppressor gene; Telomerase; TRK receptors

Indexed keywords

NERVE GROWTH FACTOR; TELOMERASE;

EID: 0030920743     PISSN: 10774114     EISSN: None     Source Type: Journal    
DOI: 10.1097/00043426-199703000-00001     Document Type: Review
Times cited : (223)

References (105)
  • 1
    • 0026607625 scopus 로고
    • Molecular basis of clinical heterogeneity in neuroblastoma
    • Brodeur GM, Nakagawara A. Molecular basis of clinical heterogeneity in neuroblastoma. Am J Pediatr Hematol Oncol 1992; 14: 111-6.
    • (1992) Am J Pediatr Hematol Oncol , vol.14 , pp. 111-116
    • Brodeur, G.M.1    Nakagawara, A.2
  • 2
    • 0028142660 scopus 로고
    • Molecular pathology of human neuroblastomas
    • Brodeur GM. Molecular pathology of human neuroblastomas. Semin Diagn Pathol 1994;11:118-25.
    • (1994) Semin Diagn Pathol , vol.11 , pp. 118-125
    • Brodeur, G.M.1
  • 3
    • 0028997723 scopus 로고
    • Molecular basis for heterogeneity in human neuroblastomas
    • Brodeur GM. Molecular basis for heterogeneity in human neuroblastomas. Eur J Cancer 1995;31A:505-10.
    • (1995) Eur J Cancer , vol.31 A , pp. 505-510
    • Brodeur, G.M.1
  • 4
    • 0343826618 scopus 로고    scopus 로고
    • Molecular basis for clinical heterogeneity: Neuroblastoma as a model
    • Rose R, Hansen O, Larsen S, eds. Mole Lyngby, Denmark: Bristol-Myers Squibb
    • Brodeur GM. Molecular basis for clinical heterogeneity: neuroblastoma as a model. In: Rose R, Hansen O, Larsen S, eds. Molecular basis for clinical heterogeneity: neuroblastoma as a model. Lyngby, Denmark: Bristol-Myers Squibb, 1996:45-54.
    • (1996) Cular Basis for Clinical Heterogeneity: Neuroblastoma as a Model , pp. 45-54
    • Brodeur, G.M.1
  • 8
    • 0015402175 scopus 로고
    • Mutation and cancer: Neuroblastoma and pheochromocytoma
    • Knudson AGJ, Strong LC. Mutation and cancer: neuroblastoma and pheochromocytoma. Am J Hum Genet 1972;24:514-22.
    • (1972) Am J Hum Genet , vol.24 , pp. 514-522
    • Knudson, A.G.J.1    Strong, L.C.2
  • 10
    • 0022000987 scopus 로고
    • Monozygotic siblings discordant for neuroblastoma: Etiologic implications
    • Kushner BH, Helson L. Monozygotic siblings discordant for neuroblastoma: etiologic implications. J Pediatr 1985;107:405-9.
    • (1985) J Pediatr , vol.107 , pp. 405-409
    • Kushner, B.H.1    Helson, L.2
  • 11
    • 0022610831 scopus 로고
    • Familial neuroblastoma: Case reports, literature review, and etiologic considerations
    • Kushner BH, Gilbert F, Helson L. Familial neuroblastoma: case reports, literature review, and etiologic considerations. Cancer 1986;57: 1887-93.
    • (1986) Cancer , vol.57 , pp. 1887-1893
    • Kushner, B.H.1    Gilbert, F.2    Helson, L.3
  • 12
    • 0025049957 scopus 로고
    • Constitutional translocation t(1;17)(p36;q12-21) in a patient with neuroblastoma
    • Laureys G, Speleman F, Opdenakker G, et al. Constitutional translocation t(1;17)(p36;q12-21) in a patient with neuroblastoma. Genes Chrom Cancer 1990;2:252-4.
    • (1990) Genes Chrom Cancer , vol.2 , pp. 252-254
    • Laureys, G.1    Speleman, F.2    Opdenakker, G.3
  • 13
    • 0027476712 scopus 로고
    • Constitutional 1p36 deletion in a child with neuroblastoma
    • Biegel JA, White PS, Marshall HN, et al. Constitutional 1p36 deletion in a child with neuroblastoma. Am J Hum Genet 1993;52:176-82.
    • (1993) Am J Hum Genet , vol.52 , pp. 176-182
    • Biegel, J.A.1    White, P.S.2    Marshall, H.N.3
  • 14
    • 0029049717 scopus 로고
    • A region of consistent deletion in neuroblastoma maps within 1p36.2-.3
    • White PS, Maris JM, Beltinger C, et al. A region of consistent deletion in neuroblastoma maps within 1p36.2-.3. Proc Nat Acad Sci USA 1995;92:5520-4.
    • (1995) Proc Nat Acad Sci USA , vol.92 , pp. 5520-5524
    • White, P.S.1    Maris, J.M.2    Beltinger, C.3
  • 15
    • 8944253286 scopus 로고    scopus 로고
    • Familial predisposition to neuroblastoma does not map to chromosome band 1p36
    • Maris JM, Kyemba SM, Rebbeck TR, et al. Familial predisposition to neuroblastoma does not map to chromosome band 1p36. Cancer Res 1996;56:3421-5.
    • (1996) Cancer Res , vol.56 , pp. 3421-3425
    • Maris, J.M.1    Kyemba, S.M.2    Rebbeck, T.R.3
  • 16
    • 0031012202 scopus 로고    scopus 로고
    • Familial neuroblastoma: New affected members and a further association with Hirschsprung disease
    • Maris JM, Chatten J, Meadows AT, et al. Familial neuroblastoma: new affected members and a further association with Hirschsprung disease. Med Pediatr Oncol 1997;28:1-5.
    • (1997) Med Pediatr Oncol , vol.28 , pp. 1-5
    • Maris, J.M.1    Chatten, J.2    Meadows, A.T.3
  • 17
    • 0022577269 scopus 로고
    • Tumour karyotype may be important in the prognosis of human neuroblastoma
    • Franke F, Rudolph B, Christiansen H, et al. Tumour karyotype may be important in the prognosis of human neuroblastoma. J Cancer Res Clin Oncol 1986;111:266-72.
    • (1986) J Cancer Res Clin Oncol , vol.111 , pp. 266-272
    • Franke, F.1    Rudolph, B.2    Christiansen, H.3
  • 18
    • 0023444756 scopus 로고
    • Chromosome findings and prognosis in neuroblastoma
    • Hayashi Y, Hanada R, Yamamoto K, et al. Chromosome findings and prognosis in neuroblastoma. Cancer Genet Cytogenet 1986;29:175-7.
    • (1986) Cancer Genet Cytogenet , vol.29 , pp. 175-177
    • Hayashi, Y.1    Hanada, R.2    Yamamoto, K.3
  • 19
    • 0023099075 scopus 로고
    • Different karyotypic patterns in early and advanced stage neuroblastomas
    • Kaneko Y, Kanda N, Maseki N, et al. Different karyotypic patterns in early and advanced stage neuroblastomas. Cancer Res 1987;47:311-8.
    • (1987) Cancer Res , vol.47 , pp. 311-318
    • Kaneko, Y.1    Kanda, N.2    Maseki, N.3
  • 20
    • 0023835841 scopus 로고
    • Tumour karyotype discriminates between good and bad prognostic outcome in neuroblastoma
    • Christiansen H, Lampert F. Tumour karyotype discriminates between good and bad prognostic outcome in neuroblastoma. Br J Cancer 1988;57:121-6.
    • (1988) Br J Cancer , vol.57 , pp. 121-126
    • Christiansen, H.1    Lampert, F.2
  • 21
    • 0021201236 scopus 로고
    • Cellular DNA content as predictor of response to chemotherapy in infants with unresectable neuroblastoma
    • Look AT, Hayes FA, Nitschke R, et al. Cellular DNA content as predictor of response to chemotherapy in infants with unresectable neuroblastoma. N Engt J Med 1984;311:231-5.
    • (1984) N Engt J Med , vol.311 , pp. 231-235
    • Look, A.T.1    Hayes, F.A.2    Nitschke, R.3
  • 22
    • 0025979843 scopus 로고
    • Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma
    • Look AT, Hayes FA, Shuster JJ, et al. Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma. J Clin Oncol 1991;9:581-91.
    • (1991) J Clin Oncol , vol.9 , pp. 581-591
    • Look, A.T.1    Hayes, F.A.2    Shuster, J.J.3
  • 23
    • 0017698493 scopus 로고
    • Chromosomal aberrations in human neuroblastomas
    • Brodeur GM, Sekhon GS, Goldstein MN. Chromosomal aberrations in human neuroblastomas. Cancer 1977;40:2256-63.
    • (1977) Cancer , vol.40 , pp. 2256-2263
    • Brodeur, G.M.1    Sekhon, G.S.2    Goldstein, M.N.3
  • 24
    • 0019777535 scopus 로고
    • Cytogenetic features of human neuroblastomas and cell lines
    • Brodeur GM, Green AA, Hayes FA, et al. Cytogenetic features of human neuroblastomas and cell lines. Cancer Res 1981;41:4678-86.
    • (1981) Cancer Res , vol.41 , pp. 4678-4686
    • Brodeur, G.M.1    Green, A.A.2    Hayes, F.A.3
  • 25
    • 0021683414 scopus 로고
    • Human neuroblastomas and abnormalities of chromosome 1 and 17
    • Gilbert F, Feder M, Balaban G, et al. Human neuroblastomas and abnormalities of chromosome 1 and 17. Cancer Res 1984;44:5444-9.
    • (1984) Cancer Res , vol.44 , pp. 5444-5449
    • Gilbert, F.1    Feder, M.2    Balaban, G.3
  • 26
    • 0024441031 scopus 로고
    • Molecular biology and genetics of human neuroblastoma
    • Brodeur GM, Fong CT. Molecular biology and genetics of human neuroblastoma. Cancer Genet Cytogenet 1989;41:153-74.
    • (1989) Cancer Genet Cytogenet , vol.41 , pp. 153-174
    • Brodeur, G.M.1    Fong, C.T.2
  • 27
    • 0024670859 scopus 로고
    • Loss of heterozygosity for chromosome 1p in human neuroblastomas: Correlation with N-myc amplification
    • Fong CT, Dracopoli NC, White PS, et al. Loss of heterozygosity for chromosome 1p in human neuroblastomas: correlation with N-myc amplification. Proc Natl Acad Sci USA 1989;86:3753-7.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3753-3757
    • Fong, C.T.1    Dracopoli, N.C.2    White, P.S.3
  • 28
    • 0024887501 scopus 로고
    • Neuroblastoma consensus deletion maps to 1p36.1-2
    • Weith A, Martinsson T, Cziepluch C, et al. Neuroblastoma consensus deletion maps to 1p36.1-2. Genes Chrom Cancer 1989;1:159-66.
    • (1989) Genes Chrom Cancer , vol.1 , pp. 159-166
    • Weith, A.1    Martinsson, T.2    Cziepluch, C.3
  • 29
    • 0027151846 scopus 로고
    • Use of the single-strand conformation polymorphism technique to detect loss of heterozygosity in neuroblastoma
    • White PS, Kaufman BA, Marshall HN, et al. Use of the single-strand conformation polymorphism technique to detect loss of heterozygosity in neuroblastoma. Genes Chrom Cancer 1993;7:102-8.
    • (1993) Genes Chrom Cancer , vol.7 , pp. 102-108
    • White, P.S.1    Kaufman, B.A.2    Marshall, H.N.3
  • 30
    • 0028258815 scopus 로고
    • There may be two tumor suppressor genes on chromosome arm 1p closely associated with biologically distinct subtypes of neuroblastoma
    • Takeda O, Homma C, Maseki N, et al. There may be two tumor suppressor genes on chromosome arm 1p closely associated with biologically distinct subtypes of neuroblastoma. Genes Chrom Cancer 1994;10:30-9.
    • (1994) Genes Chrom Cancer , vol.10 , pp. 30-39
    • Takeda, O.1    Homma, C.2    Maseki, N.3
  • 31
    • 0028067338 scopus 로고
    • Two distinct deleted regions on the short arm of chromosome 1 in neuroblastoma
    • Schleiermacher G, Peter M, Michon J, et al. Two distinct deleted regions on the short arm of chromosome 1 in neuroblastoma. Genes Chrom Cancer 1994;10:275-81.
    • (1994) Genes Chrom Cancer , vol.10 , pp. 275-281
    • Schleiermacher, G.1    Peter, M.2    Michon, J.3
  • 32
    • 0028926888 scopus 로고
    • Evidence for two tumour suppressor loci on chromosomal bands 1p35-36 involved in neuroblastoma: One probably imprinted, another associated with N-myc amplification
    • Caron H, Peter M, van Sluis P, et al. Evidence for two tumour suppressor loci on chromosomal bands 1p35-36 involved in neuroblastoma: one probably imprinted, another associated with N-myc amplification. Hum Mol Genet 1995;4:535-9.
    • (1995) Hum Mol Genet , vol.4 , pp. 535-539
    • Caron, H.1    Peter, M.2    Van Sluis, P.3
  • 33
    • 0028853718 scopus 로고
    • Deletion of chromosome 1p loci and microsatellite instability in neuroblastomas analyzed with short-tandem repeat polymorphisms
    • Martinsson T, Shoberg P-M, Hedborg F, et al. Deletion of chromosome 1p loci and microsatellite instability in neuroblastomas analyzed with short-tandem repeat polymorphisms. Cancer Res 1995;55:5681-6.
    • (1995) Cancer Res , vol.55 , pp. 5681-5686
    • Martinsson, T.1    Shoberg, P.-M.2    Hedborg, F.3
  • 34
    • 0028176145 scopus 로고
    • 1;17 Translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and cell lines
    • Van Roy N, Laureys G, Cheng NC, et al. 1;17 Translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and cell lines. Genes Chrom Cancer 1994;10:103-14.
    • (1994) Genes Chrom Cancer , vol.10 , pp. 103-114
    • Van Roy, N.1    Laureys, G.2    Cheng, N.C.3
  • 35
    • 0028023048 scopus 로고
    • Translocation involving 1p and 17q is a recurrent genetic alteration of human neuroblastoma cells
    • Savelyeva L, Corvi R, Schwab M. Translocation involving 1p and 17q is a recurrent genetic alteration of human neuroblastoma cells. Am J Hum Genet 1994;55:334-40.
    • (1994) Am J Hum Genet , vol.55 , pp. 334-340
    • Savelyeva, L.1    Corvi, R.2    Schwab, M.3
  • 36
    • 0028227933 scopus 로고
    • Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma
    • Lahti JM, Valentine M, Xiang J, et al. Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma. Nature Genet 1994;7:370-5.
    • (1994) Nature Genet , vol.7 , pp. 370-375
    • Lahti, J.M.1    Valentine, M.2    Xiang, J.3
  • 37
    • 0030586259 scopus 로고    scopus 로고
    • Cloning, chromosomal localization, and physical mapping and genomic characterization of HKR3
    • Maris JM, Jensen SJ, Sulman EP, et al. Cloning, chromosomal localization, and physical mapping and genomic characterization of HKR3. Genomics 1996;35:289-98.
    • (1996) Genomics , vol.35 , pp. 289-298
    • Maris, J.M.1    Jensen, S.J.2    Sulman, E.P.3
  • 38
    • 0030200734 scopus 로고    scopus 로고
    • Physical mapping and genomic structure of the human TNFR2 gene
    • Beltinger CP, White PS, Maris JM, et al. Physical mapping and genomic structure of the human TNFR2 gene. Genomics 1996;35:94-100.
    • (1996) Genomics , vol.35 , pp. 94-100
    • Beltinger, C.P.1    White, P.S.2    Maris, J.M.3
  • 39
    • 0028086524 scopus 로고
    • Identification of human DAN gene, mapping to the putative neuroblastoma tumor suppressor locus
    • Enomoto H, Ozaki T, Takahashi E-I, et al. Identification of human DAN gene, mapping to the putative neuroblastoma tumor suppressor locus. Oncogene 1994;9:2785-91.
    • (1994) Oncogene , vol.9 , pp. 2785-2791
    • Enomoto, H.1    Ozaki, T.2    Takahashi, E.-I.3
  • 40
    • 0027301450 scopus 로고
    • The human paired domain gene PAX7 (Hup1) maps to chromosome 1p35-1p36.2
    • Shafer BW, Mattei MG. The human paired domain gene PAX7 (Hup1) maps to chromosome 1p35-1p36.2. Genomics 1993;17:249-51.
    • (1993) Genomics , vol.17 , pp. 249-251
    • Shafer, B.W.1    Mattei, M.G.2
  • 41
    • 0027224048 scopus 로고
    • The gene for PAX7, a member of the paired-box-containing genes, is localized on human chromosome arm 1p36
    • Shapiro DN, Sublett JE, Li B, et al. The gene for PAX7, a member of the paired-box-containing genes, is localized on human chromosome arm 1p36. Genomics 1993;17:767-9.
    • (1993) Genomics , vol.17 , pp. 767-769
    • Shapiro, D.N.1    Sublett, J.E.2    Li, B.3
  • 42
    • 0029084914 scopus 로고
    • Elongin (SIII): A multisubunit regulator of elongation by RNa polymerase II
    • Aso T, Lane WS, Conaway JW, et al. Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II. Science 1995; 269:1439-43.
    • (1995) Science , vol.269 , pp. 1439-1443
    • Aso, T.1    Lane, W.S.2    Conaway, J.W.3
  • 43
    • 0029147430 scopus 로고
    • Binding of the von Hippel-Lindau tumor suppressor protein to elongin B and C
    • Kibel A, Iliopoulos O, DeCaprio JA, et al. Binding of the von Hippel-Lindau tumor suppressor protein to elongin B and C. Science 1995;269:1444-6.
    • (1995) Science , vol.269 , pp. 1444-1446
    • Kibel, A.1    Iliopoulos, O.2    DeCaprio, J.A.3
  • 44
    • 0027362625 scopus 로고
    • The retinoblastoma protein binds to a family of E2F transcription factors
    • Lees JA, Saito M, Vidal M, et al. The retinoblastoma protein binds to a family of E2F transcription factors. Mol Cell Biol 1993;13: 7813-25.
    • (1993) Mol Cell Biol , vol.13 , pp. 7813-7825
    • Lees, J.A.1    Saito, M.2    Vidal, M.3
  • 45
    • 0027280613 scopus 로고
    • Preferential amplification of the paternal allele of the N-myc gene in human neuroblastomas
    • Cheng JM, Hiemstra JL, Schneider SS, et al. Preferential amplification of the paternal allele of the N-myc gene in human neuroblastomas. Nature Genet 1993;4:191-4.
    • (1993) Nature Genet , vol.4 , pp. 191-194
    • Cheng, J.M.1    Hiemstra, J.L.2    Schneider, S.S.3
  • 46
    • 84970049889 scopus 로고
    • Allelic loss of chromosome 1p36 in neuroblastoma is of preferential maternal origin and correlates with N-myc amplification
    • Caron H, van Sluis P, van Hoeve M, et al. Allelic loss of chromosome 1p36 in neuroblastoma is of preferential maternal origin and correlates with N-myc amplification. Nature Genet 1993;4:187-90.
    • (1993) Nature Genet , vol.4 , pp. 187-190
    • Caron, H.1    Van Sluis, P.2    Van Hoeve, M.3
  • 47
    • 0024581779 scopus 로고
    • Frequent loss of heterozygosity on chromosome 14q in neuroblastoma
    • Suzuki T, Yokota J, Mugishima H, et al. Frequent loss of heterozygosity on chromosome 14q in neuroblastoma. Cancer Res 1989;49:1095-8.
    • (1989) Cancer Res , vol.49 , pp. 1095-1098
    • Suzuki, T.1    Yokota, J.2    Mugishima, H.3
  • 48
    • 0026769255 scopus 로고
    • Loss of heterozygosity for chromosomes 1 or 14 defines subsets of advanced neuroblastomas
    • Fong CT, White PS, Peterson K, et al. Loss of heterozygosity for chromosomes 1 or 14 defines subsets of advanced neuroblastomas. Cancer Res 1992;52:1780-5.
    • (1992) Cancer Res , vol.52 , pp. 1780-1785
    • Fong, C.T.1    White, P.S.2    Peterson, K.3
  • 49
    • 0026612493 scopus 로고
    • Deletion mapping of chromosomes 14q and 1p in human neuroblastoma
    • Takayama H, Suzuki T, Mugishima H, et al. Deletion mapping of chromosomes 14q and 1p in human neuroblastoma. Oncogene 1992;7:1185-9.
    • (1992) Oncogene , vol.7 , pp. 1185-1189
    • Takayama, H.1    Suzuki, T.2    Mugishima, H.3
  • 50
    • 0027254028 scopus 로고
    • Deletion of chromosome 11 and of 14q sequences in neuroblastoma
    • Srivatsan ES, Ying KL, Seeger RC. Deletion of chromosome 11 and of 14q sequences in neuroblastoma. Genes Chrom Cancer 1993;7:32-7.
    • (1993) Genes Chrom Cancer , vol.7 , pp. 32-37
    • Srivatsan, E.S.1    Ying, K.L.2    Seeger, R.C.3
  • 51
    • 0024561222 scopus 로고
    • Loss of heterozygosity on chromosomes 1p and 11p in sporadic pheochromocytoma
    • Tsutsumi M, Yokota J, Kakizoe T, et al. Loss of heterozygosity on chromosomes 1p and 11p in sporadic pheochromocytoma. J Natl Cancer Inst 1989;81:367-70.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 367-370
    • Tsutsumi, M.1    Yokota, J.2    Kakizoe, T.3
  • 52
    • 0028944776 scopus 로고
    • Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma
    • Caron H. Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma. Med Pediatr Oncol 1995;24:215-21.
    • (1995) Med Pediatr Oncol , vol.24 , pp. 215-221
    • Caron, H.1
  • 53
    • 0027274781 scopus 로고
    • Mutation of the p53 gene in neuroblastoma and its relationship with N-myc amplification
    • Imamura J, Bartram CR, Berthold F, et al. Mutation of the p53 gene in neuroblastoma and its relationship with N-myc amplification. Cancer Res 1993;53:4053-8.
    • (1993) Cancer Res , vol.53 , pp. 4053-4058
    • Imamura, J.1    Bartram, C.R.2    Berthold, F.3
  • 54
    • 0027434831 scopus 로고
    • Absence of p53 gene mutations in primary neuroblastomas
    • Vogan K, Bernstein M, Brisson L, et al. Absence of p53 gene mutations in primary neuroblastomas. Cancer Res 1993;53:5269-73.
    • (1993) Cancer Res , vol.53 , pp. 5269-5273
    • Vogan, K.1    Bernstein, M.2    Brisson, L.3
  • 55
    • 0027365309 scopus 로고
    • Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas
    • Komuro H, Hayashi Y, Kawamura M, et al. Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas. Cancer Res 1993;53:5284-8.
    • (1993) Cancer Res , vol.53 , pp. 5284-5288
    • Komuro, H.1    Hayashi, Y.2    Kawamura, M.3
  • 57
    • 0027439597 scopus 로고
    • Neurofibromatosis type 1 gene mutations in neuroblastoma
    • The I, Murthy AE, Hannigan GE. et al. Neurofibromatosis type 1 gene mutations in neuroblastoma. Nature Genet 1993;3:62-6.
    • (1993) Nature Genet , vol.3 , pp. 62-66
    • The, I.1    Murthy, A.E.2    Hannigan, G.E.3
  • 58
    • 0027211048 scopus 로고
    • Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP-ras
    • Johnson MR, Look AT, DeClue JE, et al. Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP-ras. Proc Natl Acad Sci USA 1993;90: 5539-43.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5539-5543
    • Johnson, M.R.1    Look, A.T.2    DeClue, J.E.3
  • 59
    • 0021063273 scopus 로고
    • Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour
    • Schwab M, Alitalo K, Klempnauer KH, et al. Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature 1983;305:245-8.
    • (1983) Nature , vol.305 , pp. 245-248
    • Schwab, M.1    Alitalo, K.2    Klempnauer, K.H.3
  • 60
    • 0021047844 scopus 로고
    • Transposition and amplification of oncogene-related sequences in human neuroblastomas
    • Kohl NE, Kanda N, Schreck RR, et al. Transposition and amplification of oncogene-related sequences in human neuroblastomas. Cell 1983;35:359-67.
    • (1983) Cell , vol.35 , pp. 359-367
    • Kohl, N.E.1    Kanda, N.2    Schreck, R.R.3
  • 61
    • 0021276218 scopus 로고
    • Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc
    • Schwab M, Varmus HE, Bishop JM, et al. Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc. Nature 1984;308:288-91.
    • (1984) Nature , vol.308 , pp. 288-291
    • Schwab, M.1    Varmus, H.E.2    Bishop, J.M.3
  • 62
    • 0022575467 scopus 로고
    • Gene amplification in human neuroblastomas: Basic mechanisms and clinical implications
    • Brodeur GM, Seeger RC. Gene amplification in human neuroblastomas: basic mechanisms and clinical implications. Cancer Genet Cytogenet 1986;19:101-11.
    • (1986) Cancer Genet Cytogenet , vol.19 , pp. 101-111
    • Brodeur, G.M.1    Seeger, R.C.2
  • 63
    • 0024347356 scopus 로고
    • Amplified N-myc in human neuroblastoma cells is often arranged as clustered tandem repeats of differently re-combined DNA
    • Amler LC, Schwab M. Amplified N-myc in human neuroblastoma cells is often arranged as clustered tandem repeats of differently re-combined DNA. Mol Cell Biol 1989;9:4903-13.
    • (1989) Mol Cell Biol , vol.9 , pp. 4903-4913
    • Amler, L.C.1    Schwab, M.2
  • 64
    • 0021261878 scopus 로고
    • Amplification of N-myc 3 in untreated human neuroblastomas correlates with advanced disease stage
    • Brodeur GM, Seeger RC, Schwab M, et al. Amplification of N-myc 3 in untreated human neuroblastomas correlates with advanced disease stage. Science 1984;224:1121-4.
    • (1984) Science , vol.224 , pp. 1121-1124
    • Brodeur, G.M.1    Seeger, R.C.2    Schwab, M.3
  • 65
    • 0022388606 scopus 로고
    • Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
    • Seeger RC, Brodeur GM, Sather H, et al. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 1985;313:1111-6.
    • (1985) N Engl J Med , vol.313 , pp. 1111-1116
    • Seeger, R.C.1    Brodeur, G.M.2    Sather, H.3
  • 66
    • 0023762034 scopus 로고
    • Expression of N-myc by neuroblastomas with one or multiple copies of the oncogene
    • Seeger RC, Wada R, Brodeur GM, et al. Expression of N-myc by neuroblastomas with one or multiple copies of the oncogene. Prog Clin Biol Res 1988;271:41-9.
    • (1988) Prog Clin Biol Res , vol.271 , pp. 41-49
    • Seeger, R.C.1    Wada, R.2    Brodeur, G.M.3
  • 67
    • 0026726144 scopus 로고
    • Neuroblastoma: Effect of genetic factors on prognosis and treatment
    • Brodeur GM, Azar C, Brother M, et al. Neuroblastoma: effect of genetic factors on prognosis and treatment. Cancer 1992;70:1685-94.
    • (1992) Cancer , vol.70 , pp. 1685-1694
    • Brodeur, G.M.1    Azar, C.2    Brother, M.3
  • 68
    • 0027239723 scopus 로고
    • Revisions in the international criteria for neuroblastoma diagnosis, staging, and response to treatment
    • Brodeur GM, Pritchard J, Berthold F, et al. Revisions in the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol 1993;11:1466-77.
    • (1993) J Clin Oncol , vol.11 , pp. 1466-1477
    • Brodeur, G.M.1    Pritchard, J.2    Berthold, F.3
  • 69
    • 0023260866 scopus 로고
    • Consistent N-myc copy number in simultaneous or consecutive neuroblastoma samples from sixty individual patients
    • Brodeur GM, Hayes FA, Green AA, et al. Consistent N-myc copy number in simultaneous or consecutive neuroblastoma samples from sixty individual patients. Cancer Res 1987;47:4248-53.
    • (1987) Cancer Res , vol.47 , pp. 4248-4253
    • Brodeur, G.M.1    Hayes, F.A.2    Green, A.A.3
  • 70
    • 0028843729 scopus 로고
    • Significance of chromosome 1p loss of heterozygosity in neuroblastoma
    • Maris JM, White PS, Beltinger CP, et al. Significance of chromosome 1p loss of heterozygosity in neuroblastoma. Cancer Res 1995;55:4664-9.
    • (1995) Cancer Res , vol.55 , pp. 4664-4669
    • Maris, J.M.1    White, P.S.2    Beltinger, C.P.3
  • 71
    • 0028790325 scopus 로고
    • The 1p deletion is not a reliable marker for the prognosis of patients with neuroblastoma
    • Gehring M, Berthold F, Edler L, et al. The 1p deletion is not a reliable marker for the prognosis of patients with neuroblastoma. Cancer Res 1995;55:5366-9.
    • (1995) Cancer Res , vol.55 , pp. 5366-5369
    • Gehring, M.1    Berthold, F.2    Edler, L.3
  • 72
    • 13344275864 scopus 로고    scopus 로고
    • Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma
    • Caron H, van Sluis P, de Kraker J, et al. Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma. N Engl J Med 1996;334:225-30.
    • (1996) N Engl J Med , vol.334 , pp. 225-230
    • Caron, H.1    Van Sluis, P.2    De Kraker, J.3
  • 73
    • 0024270389 scopus 로고
    • N-myc oncogene RNA expression in neuroblastoma
    • Nisen PD, Waber PG, Rich MA, et al. N-myc oncogene RNA expression in neuroblastoma. J Natl Cancer Inst 1988;80:1633-7.
    • (1988) J Natl Cancer Inst , vol.80 , pp. 1633-1637
    • Nisen, P.D.1    Waber, P.G.2    Rich, M.A.3
  • 74
    • 0025269237 scopus 로고
    • myc gene amplification and expression in primary human neuroblastoma
    • Slavc I, Ellenbogen R, Jung W-H, et al. myc gene amplification and expression in primary human neuroblastoma. Cancer Res 1990;50: 1459-63.
    • (1990) Cancer Res , vol.50 , pp. 1459-1463
    • Slavc, I.1    Ellenbogen, R.2    Jung, W.-H.3
  • 75
    • 0026552457 scopus 로고
    • Inverse relationship between trk expression and N-myc amplification in human neuroblastomas
    • Nakagawara A, Arima M, Azar CG, et al. Inverse relationship between trk expression and N-myc amplification in human neuroblastomas. Cancer Res 1992;52:1364-8.
    • (1992) Cancer Res , vol.52 , pp. 1364-1368
    • Nakagawara, A.1    Arima, M.2    Azar, C.G.3
  • 76
    • 0025646387 scopus 로고
    • Prolonged N-myc protein half-life in a neuroblastoma cell line lacking N-myc amplification
    • Cohn SL, Salwen H, Quasney MW, et al. Prolonged N-myc protein half-life in a neuroblastoma cell line lacking N-myc amplification. Oncogene 1990;5:1821-7.
    • (1990) Oncogene , vol.5 , pp. 1821-1827
    • Cohn, S.L.1    Salwen, H.2    Quasney, M.W.3
  • 77
    • 0023905449 scopus 로고
    • Incidence of ras gene mutations in neuroblastoma
    • Ballas K, Lyons J, Jannsen JWG, et al. Incidence of ras gene mutations in neuroblastoma. Eur J Pediatr 1988;147:313-4.
    • (1988) Eur J Pediatr , vol.147 , pp. 313-314
    • Ballas, K.1    Lyons, J.2    Jannsen, J.W.G.3
  • 78
    • 0024465512 scopus 로고
    • Activated N-ras oncogenes in human neuroblastoma
    • Ireland CM. Activated N-ras oncogenes in human neuroblastoma. Cancer Res 1989;49:5530-3.
    • (1989) Cancer Res , vol.49 , pp. 5530-5533
    • Ireland, C.M.1
  • 79
    • 0025857633 scopus 로고
    • Low frequency of ras gene mutations in neuroblastomas, pheochromocytomas and medullary thyroid cancers
    • Moley JF, Brother MB, Wells SA, et al. Low frequency of ras gene mutations in neuroblastomas, pheochromocytomas and medullary thyroid cancers. Cancer Res 1991;51:1596-9.
    • (1991) Cancer Res , vol.51 , pp. 1596-1599
    • Moley, J.F.1    Brother, M.B.2    Wells, S.A.3
  • 80
    • 0023901480 scopus 로고
    • Expression of Ha-ras oncogene products in human neuroblastomas and the significant correlation with a patient's prognosis
    • Tanaka T, Slamon DJ, Shimoda H, et al. Expression of Ha-ras oncogene products in human neuroblastomas and the significant correlation with a patient's prognosis. Cancer Res 1988;48:1030-4.
    • (1988) Cancer Res , vol.48 , pp. 1030-1034
    • Tanaka, T.1    Slamon, D.J.2    Shimoda, H.3
  • 81
    • 0025942776 scopus 로고
    • A significant association of Ha-ras p21 in neuroblastoma cells with patient prognosis
    • Tanaka T, Slamon DJ, Shimada H, et al. A significant association of Ha-ras p21 in neuroblastoma cells with patient prognosis. Cancer 1991;68:1296-302.
    • (1991) Cancer , vol.68 , pp. 1296-1302
    • Tanaka, T.1    Slamon, D.J.2    Shimada, H.3
  • 82
    • 0025774207 scopus 로고
    • High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor
    • Hempstead BL, Martin-Zanca D, Kaplan DR, et al. High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor. Nature 1991;350:678-83.
    • (1991) Nature , vol.350 , pp. 678-683
    • Hempstead, B.L.1    Martin-Zanca, D.2    Kaplan, D.R.3
  • 83
    • 0025735392 scopus 로고
    • The trk proto-oncogene product: A signal transducing receptor for nerve growth factor
    • Kaplan DR, Hempstead BL, Martin-Zanca D, et al. The trk proto-oncogene product: a signal transducing receptor for nerve growth factor. Science 1991;252:554-8.
    • (1991) Science , vol.252 , pp. 554-558
    • Kaplan, D.R.1    Hempstead, B.L.2    Martin-Zanca, D.3
  • 84
    • 0025857391 scopus 로고
    • The trk proto-oncogene encodes a receptor for nerve growth factor
    • Klein R, Jing S, Nanduri V, et al. The trk proto-oncogene encodes a receptor for nerve growth factor. Cell 1991;65:189-97.
    • (1991) Cell , vol.65 , pp. 189-197
    • Klein, R.1    Jing, S.2    Nanduri, V.3
  • 85
    • 0025873435 scopus 로고
    • The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3
    • Klein R, Nanduri V, Jing S, et al. The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3. Cell 1991;66:395-403.
    • (1991) Cell , vol.66 , pp. 395-403
    • Klein, R.1    Nanduri, V.2    Jing, S.3
  • 86
    • 0025944524 scopus 로고
    • trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3
    • Lamballe F, Klein R, Barbacid M. trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3. Cell 1991;66:967-79.
    • (1991) Cell , vol.66 , pp. 967-979
    • Lamballe, F.1    Klein, R.2    Barbacid, M.3
  • 87
    • 0025731382 scopus 로고
    • trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor
    • Squinto SP, Stitt TN, Aldrich TH, et al. trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor. Cell 1991;65:885-93.
    • (1991) Cell , vol.65 , pp. 885-893
    • Squinto, S.P.1    Stitt, T.N.2    Aldrich, T.H.3
  • 88
    • 0026545268 scopus 로고
    • Mammalian neurotrophin-4: Structure, chromosomal localization, tissue distribution, and receptor specificity
    • Ip NY, Ibanez CF, Nye SH, et al. Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity. Proc Natl Acad Sci USA 1992;89:3060-4.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3060-3064
    • Ip, N.Y.1    Ibanez, C.F.2    Nye, S.H.3
  • 89
    • 0027531016 scopus 로고
    • Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma
    • Nakagawara A, Arima-Nakagawara M, Scavarda NJ, et al. Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma. N Engl J Med 1993; 328:847-54.
    • (1993) N Engl J Med , vol.328 , pp. 847-854
    • Nakagawara, A.1    Arima-Nakagawara, M.2    Scavarda, N.J.3
  • 90
    • 0027456537 scopus 로고
    • Lack of high-affinity nerve growth factor receptors in aggressive neuroblastomas
    • Suzuki T, Bogenmann E, Shimada H, et al. Lack of high-affinity nerve growth factor receptors in aggressive neuroblastomas. J Natl Cancer Inst 1993;85:377-84.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 377-384
    • Suzuki, T.1    Bogenmann, E.2    Shimada, H.3
  • 91
    • 0027285262 scopus 로고
    • Coexpression of messenger RNA for TRK protooncogene and low affinity nerve growth factor receptor in neuroblastoma with favorable prognosis
    • Kogner P, Barbany G, Dominici C, et al. Coexpression of messenger RNA for TRK protooncogene and low affinity nerve growth factor receptor in neuroblastoma with favorable prognosis. Cancer Res 1993;53:2044-50.
    • (1993) Cancer Res , vol.53 , pp. 2044-2050
    • Kogner, P.1    Barbany, G.2    Dominici, C.3
  • 92
    • 0027207393 scopus 로고
    • TRK and RET protooncogene expression in human neuroblastoma specimens: High-frequency of trk expression in non-advanced stages
    • Borrello MG, Bongarzone I, Pierotti MA, et al. TRK and RET protooncogene expression in human neuroblastoma specimens: high-frequency of trk expression in non-advanced stages. Intl J Cancer 1993;54:540-5.
    • (1993) Intl J Cancer , vol.54 , pp. 540-545
    • Borrello, M.G.1    Bongarzone, I.2    Pierotti, M.A.3
  • 93
    • 0028978777 scopus 로고
    • trkA gene expression in neuroblastoma
    • Tanaka T, Hiyama E, Sugimoto T, et al. trkA gene expression in neuroblastoma. Cancer 1995;76:1086-95.
    • (1995) Cancer , vol.76 , pp. 1086-1095
    • Tanaka, T.1    Hiyama, E.2    Sugimoto, T.3
  • 94
    • 0028107269 scopus 로고
    • Expression and function of TRK-B and BDNF in human neuroblastomas
    • Nakagawara A, Azar CG, Scavarda NJ, et al. Expression and function of TRK-B and BDNF in human neuroblastomas. Mol Cell Biol 1994;14:759-67.
    • (1994) Mol Cell Biol , vol.14 , pp. 759-767
    • Nakagawara, A.1    Azar, C.G.2    Scavarda, N.J.3
  • 95
    • 0028923784 scopus 로고
    • A BDNF autocrine loop in adult sensory neurons prevents cell death
    • Acheson A, Conover JC, Fandi JP, et al. A BDNF autocrine loop in adult sensory neurons prevents cell death. Nature 1995;374:450-3.
    • (1995) Nature , vol.374 , pp. 450-453
    • Acheson, A.1    Conover, J.C.2    Fandi, J.P.3
  • 96
    • 0027323932 scopus 로고
    • Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells
    • Kaplan DR, Matsumoto K, Lucarelli E, et al. Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells. Neuron 1993;11: 321-31.
    • (1993) Neuron , vol.11 , pp. 321-331
    • Kaplan, D.R.1    Matsumoto, K.2    Lucarelli, E.3
  • 97
    • 0028948182 scopus 로고
    • TrkB affects survival, differentiation, and invasiveness of human neuroblastoma cells
    • TrkB affects survival, differentiation, and invasiveness of human neuroblastoma cells. Cancer Res 1995;55:1798-806.
    • (1995) Cancer Res , vol.55 , pp. 1798-1806
    • Matsumoto, K.1    Wada, R.K.2    Yamashiro, J.M.3
  • 98
    • 0030045649 scopus 로고    scopus 로고
    • Expression of TrkC in favorable human neuroblastomas
    • Yamashiro DJ, Nakagawara A, Ikegaki N, et al. Expression of TrkC in favorable human neuroblastomas. Oncogene 1996;12:37-41.
    • (1996) Oncogene , vol.12 , pp. 37-41
    • Yamashiro, D.J.1    Nakagawara, A.2    Ikegaki, N.3
  • 99
    • 0024548599 scopus 로고
    • Expression of a multidrug resistance gene in human tumors
    • Goldstein LJ, Galski H, Fojo A, et al. Expression of a multidrug resistance gene in human tumors. J Natl Cancer Inst 1989;81:116-24.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 116-124
    • Goldstein, L.J.1    Galski, H.2    Fojo, A.3
  • 100
    • 0025169822 scopus 로고
    • Expression of the multidrug resistance, MDR1, gene in neuroblastomas
    • Goldstein LJ, Fojo AT, Ueda K, et al. Expression of the multidrug resistance, MDR1, gene in neuroblastomas. J Clin Oncol 1990;8:128-36.
    • (1990) J Clin Oncol , vol.8 , pp. 128-136
    • Goldstein, L.J.1    Fojo, A.T.2    Ueda, K.3
  • 101
    • 0025990960 scopus 로고
    • P-glycoprotein expression as a predictor of the outcome of therapy for neuroblastoma
    • Chan HSL, Haddad G, Thorner PS, et al. P-glycoprotein expression as a predictor of the outcome of therapy for neuroblastoma. N Engl J Med 1991;325:1608-14.
    • (1991) N Engl J Med , vol.325 , pp. 1608-1614
    • Chan, H.S.L.1    Haddad, G.2    Thorner, P.S.3
  • 102
    • 0030031845 scopus 로고    scopus 로고
    • Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma
    • Norris MD, Bordow SB, Marshall GM, et al. Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma. N Engl J Med 1996;334:231-8.
    • (1996) N Engl J Med , vol.334 , pp. 231-238
    • Norris, M.D.1    Bordow, S.B.2    Marshall, G.M.3
  • 103
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse KR, et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994;266:2011-5.
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3
  • 104
    • 84993876589 scopus 로고
    • Correlating telomerase activity levels with human neuroblastoma outcomes
    • Hiyama E, Hiyama K, Yokoyama T, et al. Correlating telomerase activity levels with human neuroblastoma outcomes. Nature Med 1995;1:249-55.
    • (1995) Nature Med , vol.1 , pp. 249-255
    • Hiyama, E.1    Hiyama, K.2    Yokoyama, T.3
  • 105
    • 84993867980 scopus 로고
    • Do the ends justify the means?
    • Brodeur GM. Do the ends justify the means? Nature Med 1995; 1:203-5.
    • (1995) Nature Med , vol.1 , pp. 203-205
    • Brodeur, G.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.