Epidermal growth factor receptor and labeling index are independent prognostic factors in glial tumor outcome

Clinical Cancer Research

Volumn 4, Issue 10, 1998, Pages 2383-2390

  Etienne, Marie Christine ^a   Formento, Jean Louis ^a   Lebrun Frenay, Christine ^b   Gioanni, Jeanine ^a   Chatel, Marcel ^b   Paquis, Philippe ^b   Bernard, Christine ^a   Courdi, Adel ^a   Bensadoun, René Jean ^a   Pignol, Jean Philippe ^a   Francoual, Mireille ^a   Grellier, Patrick ^b   Frenay, Marc ^a   Milano, Gérard ^a,c  

^a CENTRE ANTOINE LACASSAGNE   (France)

^b PASTEUR HOSPITAL   (France)

^c CENTRE ANTOINE LACASSAGNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ETOPOSIDE; FOTEMUSTINE; IODINE 125;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER SURVIVAL; CENTRAL NERVOUS SYSTEM TUMOR; FEMALE; GLIOBLASTOMA; GLIOMA; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; PRIORITY JOURNAL; PROGNOSIS;

ADOLESCENT; ADULT; AGED; CELL DIVISION; FEMALE; GLIOMA; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROGNOSIS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SURVIVAL RATE; THYMIDINE;

EID: 0031784413     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Saleman, M. Glioblastoma and malignant astrocytoma. In: A. H. Kaye, and E. R. Laws, Jr. (eds.). Brain Tumors, pp. 449-477. London: Churchill Livingstone, 1995.
2. Duncan, G. G., Goodman, G. B., Ludgate, C. M., and Rheaume, D. E. The treatment of adult supratentorial high grade astrocytomas. J. Neuro-Oncol., 13: 63-72, 1992.
3. Philippon, J. H., Clemenceau, S. H., Fauchon, F. H., and Foncin, J. H. Supratentorial low-grade astrocytomas in adults. Neurosurgery, 32: 554-559, 1993.
4. Salmon, I., Kiss, R., Dewitte, O., Gras, T., Pasteels, J. L., Brotchi, J., and Flament-Durand, J. Histopathologic grading and DNA ploidy in relation to survival among 206 adult astrocytic tumor patients. Cancer (Phila.), 70: 538-546, 1992.
5. Kim, T. S., Halliday, A. L., Hedley-Whyte, E. T., and Convery, K. Correlates of survival and the Daumas-Duport grading system for astrocytomas. J Neurosurg., 74: 27-37, 1991.
6. Devaux, B. C., O'Fallon, J. R., and Kelly, P. J. Resection, biopsy and survival in malignant glial neoplasms. A retrospective study of clinical parameters, therapy and outcome. J. Neurosurg., 78: 767-775, 1993.
7. Sainsbury, J. R. C., Farndon, J. R., Needham, G. K., Malcom, A. J., and Harris, A. L. Epidermal growth factor receptor as predictor for early recurrence of and death from breast cancer. Lancet, i: 1398-1402, 1987.
8. Neal, D. E., Marsh, C., Bennett, M. K., Abel, P. D., Hall, R. R., Sainsbury, J. R. C., and Harris, A. L. Epidermal growth factor receptors in human bladder cancer. Comparisons of invasive and superficial tumors. Lancet, i: 366-368, 1985.
9. Ozawa, S., Ueda, M., Ando, N., Shimizu, N., and Abe, O. Prognostic significance of epidermal growth factor receptor in esophageal squamous cell carcinomas. Cancer (Phila.), 63: 2169-2173, 1989.
10. Pfeiffer, D., Stellwag, B., Pfeiffer, A., Borlinghaus, P., Meier, W., and Scheidel, P. Clinical implications of the epidermal growth factor receptor in the squamous cell carcinoma of the uterine cervix. Gynecol. Oncol., 33: 146-150, 1989.
11. Bauknecht, T., Kohler, M., Janz, I., and Pfleiderer, A. The occurrence of epidermal growth factor receptors and the characterization of EGF-like factors in human ovarian, endometrial, cervical and breast cancer. J. Cancer Res. Clin. Oncol., 115: 193-199, 1989.
12. Hendler, F., Shum Siu, A., Nanu, L., and Ozanne, B. Overexpression of EGF receptors in squamous tumors is associated with poor survival. J. Cell. Biochem., (Suppl. 12A): 105, 1988.
13. Dassonville, O., Formento, J. L., Francoual, M., Ramaioli, A., Santini, J., Schneider, M., Demard, F., and Milano, G. Expression of epidermal growth factor receptor and survival in upper aerodigestive tract cancer. J. Clin. Oncol., 11: 1873-1878, 1993.
14. Maurizi, M., Almadori, G., Ferrandina, G., Distefano, M., Romanini, M. E., Cadoni, G., Benedetti-Panici, P., Paludetti, G., Scambia, G., and Mancuso, S. Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma. Br. J. Cancer, 74: 1253-1257, 1996.
15. Libermann, T. A., Razon, N., Bartal, A. D., Yarden, Y., Schlessinger, J., and Soreg, H. Expression of epidermal growth factor receptors in human brain tumors. Cancer Res., 44: 753-760, 1984.
16. Arita, N., Hayakawa, T., Izumoto, S., Taki, T., Ohnishi, T., Yamamoto, H., Bitoh, S., and Mogami, H. Epidermal growth factor receptor in human glioma. J. Neurosurg., 70: 916-919, 1989.
17. Maiden, L. T., Novak, U., Kaye, A. H., and Burgess, A. W. Selective amplification of the cytoplasmic domain of the epidermal growth factor receptor gene in glioblastoma multiforme. Cancer Res., 48: 2711-2714, 1988.
18. Wong, A. J., Bigner, S. H., Bigner, D. D., Kinzler, K. W., Hamilton. S. R., and Vogelstein, B. Increased expression of the epidermal growth factor receptor gene in malignant gliomas invariably associated with gene amplification. Proc. Natl. Acad. Sci. USA, 84: 6899-6903, 1987.
19. Jaros, E., Perry, R. H., Adam, L., Kelly, P. J., Crawford, P. J., Kalbag, R. M., Mendelow, A. D., Sengupta, R. P., and Pearson, A. D. J. Prognostic implications of p53 protein, epidermal growth factor receptor, and ki-67 labelling in brain tumours. Br. J. Cancer, 66: 373-385, 1992.
20. Zhu, A., Shaeffer, J., Leslie, S., Kolm, P., and El-Mahdi, A. M. Epidermal growth factor receptor: an independent predictor of survival in astrocytic tumors given definitive irradiation. Int. J. Radiat. Oncol. Biol. Phys., 34: 809-815, 1996.
21. Santini, J., Formento, J. L., Francoual, M., Milano, G., Schneider, M., Dassonville, O., and Demard, F. Characterization, quantification and potential clinical value of the epidermal growth factor receptor in head and neck squamous cell carcinomas. Head Neck, 13: 132-139, 1991.
22. Chauvel, P., Courdi, A., Gioanni, J., Vallicioni, J., Santini, J., and Demard, F. The labelling index: a prognostic factor in head and neck carcinoma. Radiother. Oncol., 14: 231-237, 1989.
23. Louis, D. N., and Gusella, J. F. A tiger behind many doors: multiple genetic pathways to malignant glioma. Trends Genet., 11: 412-415, 1995.
24. Agosti, R. M., Leuthold, M., Gullick, W. J., Yasargil, M. G., and Wiestler, O. D. Expression of the epidermal growth factor receptor in astrocytic tumours is specifically associated with glioblastoma multiforme. Virchows Arch. A Pathol. Anat., 420: 321-325, 1992.
25. Collins, V. P. Gene amplification in human gliomas. Glia, 15: 289-296, 1995.
26. Wong, A. J., Ruppert, J. M., Bigner, S. H., Grzeschik, C. H., Humphrey, P. A., Bigner, D. S., and Vogelstein, B. Structural alterations of the epidermal growth factor receptor gene in human gliomas. Proc. Natl. Acad. Sci. USA, 89: 2965-2969, 1992.
27. Kurpad, S. N., Zhao, X-G., Wikstrand, C. J., Batra, S. K., McLendon, R. E., and Bigner, D. S. Tumor antigens in astrocytic gliomas. Glia, 15: 244-256, 1995.
28. Ekstrand, A. J., Longo, N., Hamid, M. L., Olson, J. J., Liu, L., Collins, V. P., and James, C-D. Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastoma with EGFR gene amplification. Oncogene, 9: 2313-2320, 1994.
29. Schlegel, J., Merdes, A., Stumm, G., Albert, F. K., Forsting, M., Hynes, N., and Kiessling, M. Amplification of the epidermal-growth-factor receptor gene correlates with different growth behaviour in human glioblastoma. Int. J. Cancer, 56: 72-77, 1994.
30. Moscatello, D. K., Holgado-Madruga, M., Godwin, A. K., Ramirez, G., Gunn, G., Zoltick, P. W., Biegel, J. A., Hayes, R. L., and Wong, A. J. Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors. Cancer Res., 55: 5536-5539, 1995.
31. Burger, P. C., Vogel, F. S., Green, S. B., and Strike, T. A. Glioblastoma multiforme and anaplastic astrocytoma. Pathologic criteria and prognostic implications. Cancer (Phila.), 56: 1106-1111, 1985.
32. Ammirati, M., Vick, N., Liao, Y., Ciric, I., and Mikhael, M. Effect of the extent of surgical resection on survival and quality of life in patients with supratentorial glioblastomas and anaplastic astrocytomas. Neurosurgery, 21: 201-206, 1987.
33. Tubiana, M., and Courdi, A. Cell proliferation kinetics in human solid tumors: relation to probability of metastatic dissemination and long-term survival. Radiother. Oncol., 15: 1-18, 1989.
34. Nishizaki, T., Orita, T., Kajiwara, K., Ikeda, N., Ohshita, N., Nakayama, H., Furntani, Y., Ikeyama, Y., and Akimura, T. Correlation of in vitro bromodeoxyuridine labeling index and DNA aneuploidy with survival or recurrence in brain-tumor patients. J. Neurosurg., 73: 396-400, 1990.
35. Hoshino, T., Ahn, D., Prados, M. D., Lamborn, K., and Wilson, C. B. Prognostic significance of the proliferative potential of intracranial gliomas measured by bromodeoxyuridine labeling. Int. J. Cancer, 53: 550-555, 1993.
36. Nagane, M., Coufal, F., Lin, H., Bögler, O., Cavenee. W. K., and Su-Huang, H-J. A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis. Cancer Res., 56: 5079-5086, 1996.