Effects of hepatocyte growth factor (HGF) on human glioma cells in vitro: HGF acts as a motility factor in glioma cells

International Journal of Cancer

Volumn 66, Issue 5, 1996, Pages 678-685

  Moriyama, Takuzou ^a   Kataoka, Hiroaki ^a   Seguchi, Kohji ^a   Tsubouchi, Hirohito ^a   Koono, Masashi ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE; GELATINASE A; GROWTH FACTOR RECEPTOR; RECOMBINANT SCATTER FACTOR; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL MIGRATION; CHEMOKINESIS; CHEMOTAXIS; CONTROLLED STUDY; GENE EXPRESSION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

CELL DIVISION; CELL MOVEMENT; CHEMOTACTIC FACTORS; GELATINASES; GENE EXPRESSION; GLIOBLASTOMA; HEPATOCYTE GROWTH FACTOR; HUMANS; MATRIX METALLOPROTEINASE 2; METALLOENDOPEPTIDASES; PROTO-ONCOGENE PROTEINS C-MET; RECEPTOR PROTEIN-TYROSINE KINASES; RECOMBINANT PROTEINS; RNA, MESSENGER; STIMULATION, CHEMICAL; TUMOR CELLS, CULTURED;

EID: 0029951336     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19960529)66:5<678::AID-IJC16>3.0.CO;2-0     Document Type: Article

References (29)

1. BELLUSCI, S., MOENS, G., GAUDINO, G., COMOGLIO, P., NAKAMURA, T., THIERY, J.-P. and JOUANNEAU, J., Creation of a hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity. Oncogene, 9, 1091-1099 (1994).
2. BOTTARO, D.P., RUBIN, J.S., FALETTO, D.L., CHAN, A.M.-L., KMIECIK, T.E., VANDE WOUDE, G.F. and AARONSON, S.A., Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science (Wash.), 251, 802-804 (1991).
3. COOPER, C.S., PARK, M., BLAIR, D.G., TAINSKY, M.A., HUEBNER, K., CROCE, C.M. and VANDE WOUDE, G.F., Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature (Lond.), 311, 29-33 (1984).
4. DI RENZO, M.F., NARSIMHAN, R.P., OLIVERO, M., BRETTI, S., GIORDANO, S., MEDICO, E., GAGLIA, P., ZARA, P. and COMOGLIO, P.M., Expression of the Met/HGF receptor in normal and neoplastic human tissues. Oncogene, 6, 1997-2003 (1991).
5. ENGEBRAATEN, O., BJERKVIG, R., PEDERSEN, P.-H. and LAERUM, O.D., Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumour biopsies in vitro. Int. J Cancer, 53, 209-214 (1993).
6. FERRACINI, R., DI RENZO, M.F., SCOTLANDI, K., BALDINI, N., OLIVERO, M., LOLLINI, P., CREMONA, O., CAMPANACCI, M. and COMOGLIO, P.M., The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit. Oncogene, 10, 739-749 (1995).
7. GHERARDI, E., GRAY, J., STOKER, M., PERRYMAN, M. and FURLONG, R., Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement. Proc. nat. Acad. Sci. (Wash.), 86, 5844-5848 (1989).
8. GIORDANO, S., PONZETTO, C., DI RENZO, M.F., COOPER, C.S. and COMOGLIO, P.M., Tyrosine kinase receptor indistinguishable from the c-met protein. Nature (Lond ). 339, 155-156 (1989).
9. GOHDA, E., TSUBOUCHI, H., NAKAYAMA, H., HIRONO, S., SAKIYAMA, O., TAKAHASHI, K., MIYAZAKI, H., HASHIMOTO, S. and DAIKUHARA, Y., Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure. J. clin. Invest., 81, 414-419 (1988).
10. JUNG, W., CASTREN, E., ODENTHAL, M., VANDE WOUDE, G.F., ISHII, T., DIENES, H.-P., LINDHOLM, D. and SCHIRMACHER, P., Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain. J. Cell Biol., 126, 485-494 (1994).
11. LUND-JOHANSEN, M., BJERKVIG, R., HUMPHREY, P.A., BIGNER, S.H., BIGNER, D.D. and LAERUM, O.-D., Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro. Cancer Res., 50, 6039-6044 (1990)
12. LUND-JOHANSEN, M., RUCKLIDGE, G.J., MILNE, G. and BJERKVIG, R., A metalloproteinase, capable of destroying cultured brain tissue isolated from rat glioma cells. Anticancer Res., 11, 1001-1006 (1991).
13. MIYAZAWA, K., SHIMOMURA, T., KITAMURA, A., KONDO, J., MORIMOTO, Y. and KITAMURA, N., Molecular cloning and sequence analysis of the cDNA for a human serine protease responsible for activation of hepatocyte growth factor. J biol. Chem., 268, 10024-10028 (1993).
14. MORIYAMA, T., KATAOKA, H., TSUBOUCHI, H. and KOONO, M., Concomitant expression of hepatocyte growth factor (HGF), HGF activator and c-met genes in human glioma cells in vitro. FEBS Lett. 372, 78-82 (1995).
15. NAKAMURA, T., NAWA, K., ICHIHARA, A., KAISE, N. and NISHINO, T., Purification and subunit structure of hepatocyte growth factor from rat platelets. FEBS Lett., 224, 311-316 (1987).
16. NAKANO, A., TANI, E., MIYAZAKI, K., YAMAMOTO, Y. and FURUYAMA., J., Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas. J. Neurosurg., 83, 298-307 (1995).
17. NALDINI, L., TAMAGNONE, L., VIGNA, E., SACHS, M., HARTMANN, G., BIRCHMEIER, W., DAIKUHARA, Y., TSUBOUCHI, H., BLASI, F. and COMOGLIO, P.M., Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. EMBO J., 11, 4825-4833 (1992).
18. NALDINI, L., WEIDNER, K.M., VIGNA, E., GAUDINO, G., BARDELLI, A., PONZETTO, C., NARIMHAN, R.P., HARTMANN, G., ZARNEGAR, R., MICHALOPOULOS, G.K., BIRCHMEIER, W. and COMOGLIO, P.M., Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J., 10, 2867-2878 (1991).
19. OHNSHI, T., ARITA, N., HAYAKAWA, T., KAWAHARA, K., KATO, K. and KAKINUMA, A., Purification of motility factor (GMF) from human malignant glioma cells and its biological significance in tumor invasion. Biochem. biophys. Res. Comm., 193, 518-525 (1993).
20. PISTERS, L.L., TRONCOSO, P., ZHAU, H.E., LI, W., VONESCHENBACH, A.C. and CHUNG, L.W.K., C-met proto-oncogene expression in benign and malignant human prostate tissues. J. Urol., 154, 293-298 (1995).
21. PRAT, M., NARSIMHAN, R.P., CREPALDI, T., MICOTRA, M.R., NATALI, P.G. and COMOGLIO, P.M., The receptor encoded by the human c-met oncogene is expressed in hepatocytes, epithelial cells and solid tumors. Int J. Cancer, 49, 323-328 (1991).
22. RUBIN, J.S., BOTTARO, D.P. and AARONSON, S.A., Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product. Biochim. biophys. Acta, 1155, 357-371 (1993).
23. SONNENBERG, E., MEYER, D., WEIDNER, K.M. and BIRCHMEIER, C., Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development. J. Cell Biol., 123, 223-235 (1993).
24. STOKER, M., GHERARDI, E., PERRYMAN, M. and GRAY, J., Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature (Lond.), 327, 239-242 (1987).
25. TEMPEST, P.R., STRATTON, M.R. and COOPER, C.S., Structure of the met protein and variation of met protein kinase activity among human tumour cell lines Brit. J. Cancer. 58, 3-7 (1988).
26. TSUBOUCHI, H., NIITANI, Y., HIRONO, S., NAKAYAMA, H., GOHDA, E., ARAKAKI, N., SAKIYAMA, O., TAKAHASHI, K., KIMOTO, M., KAWAKAMI, S., SETOGUCHI, M., TACHIKAWA, T., SHIN, S., ARIMA, T. and DAIKUHARA, Y., Levels of the human hepatocyte growth factor in serum of patients with various liver diseases determined by an enzyme-linked immunosorbent assay. Hepatology, 13, 1-5 (1991).
27. WEIDNER, K.M., ARAKAKI, N., HARTMANN, G., VANDEKERCKHOVE, J., WEINGART, S., RIEDER, H., FONATSCH, C., TSUBOUCHI, H., HISHIDA, T., DAIKUHARA, Y. and BIRCHMEIER, W., Evidence for the identity of human scatter factor and human hepatocyte growth factor. Proc. nat. Acad. Sci. (Wash.), 88, 7001-7005 (1991).
28. WULLICH, B., SATTLER, H.-P., FISCHER, U. and MEESE, E., Two independent amplification events on chromosome 7 in glioma: amplification of the epidermal growth factor receptor gene and amplification of the oncogene MET. Anticancer Res., 14, 577-580 (1994).
29. YAMADA, T., TSUBOUCHI, H., DAIKUHARA, Y., PRAT, M., COMOGLIO, P.M., MCGEER, P.L. and MCGEER, E.G., Immunohistochemistry with antibodies to hepatocyte growth factor and its receptor protein (c-MET) in human brain tissues. Brain Res., 637, 308-312 (1994).