메뉴 건너뛰기




Volumn 56, Issue 6, 1996, Pages 1457-1465

Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness

Author keywords

[No Author keywords available]

Indexed keywords

NEU DIFFERENTIATION FACTOR;

EID: 0029879442     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (162)

References (64)
  • 1
    • 0026487597 scopus 로고
    • The type 1 (EGFR-related) family of growth factor receptors and their ligands
    • Prigent, S. A., and Lemoine, N. R. The type 1 (EGFR-related) family of growth factor receptors and their ligands Progress Growth Factor Res., 4- 1-24, 1992.
    • (1992) Progress Growth Factor Res. , vol.4 , pp. 1-24
    • Prigent, S.A.1    Lemoine, N.R.2
  • 3
    • 0027548648 scopus 로고
    • Amplification and overexpression of the erbB-1 gene in human tumors, its involvement in tumor development, significance as a prognostic factor, and potential as a target for cancer therapy
    • Hynes, N. E. Amplification and overexpression of the erbB-1 gene in human tumors, its involvement in tumor development, significance as a prognostic factor, and potential as a target for cancer therapy. Semm. Cancer Biol., 4: 19-25, 1993.
    • (1993) Semm. Cancer Biol. , vol.4 , pp. 19-25
    • Hynes, N.E.1
  • 4
    • 0028008469 scopus 로고
    • The receptor for EGF and its ligands: Expression, prognostic value and target for therapy
    • Modjtahedi, H , and Dean, C. The receptor for EGF and its ligands: expression, prognostic value and target for therapy. Int. J. Oncol., 4: 277-296, 1994.
    • (1994) Int. J. Oncol. , vol.4 , pp. 277-296
    • Modjtahedi, H.1    Dean, C.2
  • 5
    • 0028028068 scopus 로고
    • Receptor blockade with monoclonal antibodies as anti-cancer therapy
    • Baselga, J., and Mendelsohn, J. Receptor blockade with monoclonal antibodies as anti-cancer therapy. Pharmacol. & Ther., 64: 127-154, 1994.
    • (1994) Pharmacol. & Ther. , vol.64 , pp. 127-154
    • Baselga, J.1    Mendelsohn, J.2
  • 6
    • 0028960781 scopus 로고
    • Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells
    • Radinsky, R., Risin, S., Fan, D., Dong, Z., Bielenberg, D., Bucana, C. D., and Fidler, I. J. Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells. Clin Cancer Res., 1: 19-31, 1995
    • (1995) Clin Cancer Res. , vol.1 , pp. 19-31
    • Radinsky, R.1    Risin, S.2    Fan, D.3    Dong, Z.4    Bielenberg, D.5    Bucana, C.D.6    Fidler, I.J.7
  • 7
    • 0029049891 scopus 로고
    • Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor α in the progression of prostatic neoplasms
    • Scher, H. I., Sarkis, A., Reuter, V., Cohen, D , Netto, G., Petrylak, D., Lianes, P., Fuks, Z., Mendelsohn, J , and Cordon-Cardo, C. Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor α in the progression of prostatic neoplasms. Clin Cancer Res., 1: 545-550, 1995.
    • (1995) Clin Cancer Res. , vol.1 , pp. 545-550
    • Scher, H.I.1    Sarkis, A.2    Reuter, V.3    Cohen, D.4    Netto, G.5    Petrylak, D.6    Lianes, P.7    Fuks, Z.8    Mendelsohn, J.9    Cordon-Cardo, C.10
  • 8
    • 0027154633 scopus 로고
    • Assignment of heregulin (HGL) to human chromosome 8p22-p11 by PCR analysis of somatic cell hybrid DNA
    • Lee, J , and Wood, W. I. Assignment of heregulin (HGL) to human chromosome 8p22-p11 by PCR analysis of somatic cell hybrid DNA Genomics. 16: 790-791, 1993
    • (1993) Genomics. , vol.16 , pp. 790-791
    • Lee, J.1    Wood, W.I.2
  • 11
    • 0026776424 scopus 로고
    • Isolation of the neu/HER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells
    • Peles, E., Bacus, S. S., Koski, R. A , Lu, H. S., Wen, D., Ogden, S. G., Levy, R. B , and Yarden, Y Isolation of the neu/HER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumor cells Cell. 69: 205-216, 1992.
    • (1992) Cell , vol.69 , pp. 205-216
    • Peles, E.1    Bacus, S.S.2    Koski, R.A.3    Lu, H.S.4    Wen, D.5    Ogden, S.G.6    Levy, R.B.7    Yarden, Y.8
  • 14
    • 0027712105 scopus 로고
    • The role of erbB2 signal transducuon pathways in human breast cancer
    • Lupu, R., and Lippman, M. E. The role of erbB2 signal transducuon pathways in human breast cancer. Breast Cancer Res Treat., 27 83-93, 1993.
    • (1993) Breast Cancer Res Treat. , vol.27 , pp. 83-93
    • Lupu, R.1    Lippman, M.E.2
  • 15
    • 0027526321 scopus 로고
    • ARIA, a protein that stimulates acetylcholme receptor synthesis, is a member of the neu ligand family
    • Falls, D L , Rosen, K M., Corfas, G., Lane, W. S., and Fischbach, G. D. ARIA, a protein that stimulates acetylcholme receptor synthesis, is a member of the neu ligand family. Cell, 72: 801-815, 1993.
    • (1993) Cell , vol.72 , pp. 801-815
    • Falls, D.L.1    Rosen, K.M.2    Corfas, G.3    Lane, W.S.4    Fischbach, G.D.5
  • 17
    • 0029040445 scopus 로고
    • SMDF, a novel heregulin isoform hishly expressed in sensory and motor neurons
    • Ho, W-H., Armanini, M. P., Nuijens, A., Phillips, H. S , and Osheroff, P. L. SMDF, a novel heregulin isoform hishly expressed in sensory and motor neurons. J. Biol. Chem., 270: 14523-14532, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14523-14532
    • Ho, W.-H.1    Armanini, M.P.2    Nuijens, A.3    Phillips, H.S.4    Osheroff, P.L.5
  • 18
    • 0028176477 scopus 로고
    • A neu acquaintance for erbB3 and erbB4: A role for receptor heterodimerization in growth signaling
    • Carraway, K. L., and Cantley, L. C. A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling. Cell, 78: 5-8, 1994.
    • (1994) Cell , vol.78 , pp. 5-8
    • Carraway, K.L.1    Cantley, L.C.2
  • 19
    • 0029021518 scopus 로고
    • Heterodimenzation and functional interaction between EGF receptor family members: A new signaling paradigm with implications for breast cancer research
    • Earp, H. S., Dawson, T. L., Li, X., and Yu, H. Heterodimenzation and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research. Breast Cancer Res. Treat, 35: 115-132, 1995.
    • (1995) Breast Cancer Res. Treat , vol.35 , pp. 115-132
    • Earp, H.S.1    Dawson, T.L.2    Li, X.3    Yu, H.4
  • 20
    • 0028937327 scopus 로고
    • Neu differentiation factor inhibits EGF binding: A model for trans-regulation within the ErbB family of receptor tyrosine kinases
    • Kaninagaran, D., Tzahar, E. Liu, N., Wen, D., and Yarden, Y. Neu differentiation factor inhibits EGF binding: a model for trans-regulation within the ErbB family of receptor tyrosine kinases. J. Biol. Chem., 270: 9982-9990, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 9982-9990
    • Kaninagaran, D.1    Tzahar, E.2    Liu, N.3    Wen, D.4    Yarden, Y.5
  • 22
    • 0028893444 scopus 로고
    • Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling
    • Graus-Porta, D., Beerli, R. R., and Hynes, N. E. Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling. Mol. Cell. Biol., 15: 1182-1191, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1182-1191
    • Graus-Porta, D.1    Beerli, R.R.2    Hynes, N.E.3
  • 23
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Washington DC
    • Slamon, D. J., Clark, G. M., Wong, S. G., Levin, W. J., Ullrich, A., and McGuire, W L. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science (Washington DC), 235: 177-182, 1987.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 25
    • 0028670125 scopus 로고
    • The biology of erbB-2/neu/HER-2 and its role in cancer
    • Hynes, N E., and Stern, D. F. The biology of erbB-2/neu/HER-2 and its role in cancer Biochim. Biophys. Acta. 1198: 165-184, 1994.
    • (1994) Biochim. Biophys. Acta , vol.1198 , pp. 165-184
    • Hynes, N.E.1    Stern, D.F.2
  • 26
    • 0026899636 scopus 로고
    • A ligand for the erbB-2 oncogene product (gp30) induces differentiation of human breast cancer cells
    • Bacus, S. S., Huberman, E., Chin, D , Kiguchi, K., Simpson, S , Lippman, M., and Lupu, R. A ligand for the erbB-2 oncogene product (gp30) induces differentiation of human breast cancer cells Cell Growth & Differ., 3: 401-411, 1992.
    • (1992) Cell Growth & Differ. , vol.3 , pp. 401-411
    • Bacus, S.S.1    Huberman, E.2    Chin, D.3    Kiguchi, K.4    Simpson, S.5    Lippman, M.6    Lupu, R.7
  • 27
    • 0024478054 scopus 로고
    • HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor
    • HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor. Mol. Cell. Biol., 9: 1165-1172, 1989
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1165-1172
    • Hudziak, R.M.1    Lewis, G.D.2    Winget, M.3    Fendly, B.M.4    Shepard, H.M.5    Ullnch, A.6
  • 28
    • 0025318271 scopus 로고
    • Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product
    • Fendly, B. M., Winget M., Hudziak, R. M., Lipari, M. T , Napier, M. A , and Ullrich, A. Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product. Cancer Res. 50: 1550-1558, 1990
    • (1990) Cancer Res. , vol.50 , pp. 1550-1558
    • Fendly, B.M.1    Winget, M.2    Hudziak, R.M.3    Lipari, M.T.4    Napier, M.A.5    Ullrich, A.6
  • 32
    • 0028949081 scopus 로고
    • Heregulin stimulates autogenesis and phosphatidylinositol 3-kinase in mouse fibroblasts transfected with erbB2/neu and erbB3
    • Carraway, K. L., Soltoff, S. P , Diamonti, A. J., and Cantley, L. C. Heregulin stimulates autogenesis and phosphatidylinositol 3-kinase in mouse fibroblasts transfected with erbB2/neu and erbB3. J. Biol. Chem., 270: 7111-7116, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7111-7116
    • Carraway, K.L.1    Soltoff, S.P.2    Diamonti, A.J.3    Cantley, L.C.4
  • 33
    • 0027971393 scopus 로고
    • ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms
    • Tzahar, E., Levkowitz, G., Kaninagaran, D., Yi, L., Peles, E , Lavi, S , Chang, D., Liu, N., Yayon, A., Wen, D., and Yarden, Y. ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms. J. Biol. Chem., 269: 25226-25233, 1994
    • (1994) J. Biol. Chem. , vol.269 , pp. 25226-25233
    • Tzahar, E.1    Levkowitz, G.2    Kaninagaran, D.3    Yi, L.4    Peles, E.5    Lavi, S.6    Chang, D.7    Liu, N.8    Yayon, A.9    Wen, D.10    Yarden, Y.11
  • 34
    • 0028910546 scopus 로고
    • Targeted inhibition of tumor-cell growth by recombinant heregulin-toxin fusion proteins
    • Jeschke, M., Wels, W., Dengler, W., Imber, R., Stocklin, E., and Groner, B. Targeted inhibition of tumor-cell growth by recombinant heregulin-toxin fusion proteins. Int J. Cancer. 60. 730-739, 1995.
    • (1995) Int J. Cancer. , vol.60 , pp. 730-739
    • Jeschke, M.1    Wels, W.2    Dengler, W.3    Imber, R.4    Stocklin, E.5    Groner, B.6
  • 36
    • 0027536097 scopus 로고
    • Demonstration of ligand-dependent signaling by the erbB-3 tyrosme kinase and its constitutive activation in human breast tumor cells
    • Kraus, M. H., Fedi, P., Starts, R., Muraro, R., and Aaronson, S. A. Demonstration of ligand-dependent signaling by the erbB-3 tyrosme kinase and its constitutive activation in human breast tumor cells. Proc. Natl Acad. Sci. USA, 90: 2900-2904, 1993.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 2900-2904
    • Kraus, M.H.1    Fedi, P.2    Starts, R.3    Muraro, R.4    Aaronson, S.A.5
  • 38
    • 0023301170 scopus 로고
    • Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms
    • Kraus, M. H., Popescu, N. C., Amsbaugh, S. C., and King, C. R. Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms. EMBO J., 6: 605-610, 1987.
    • (1987) EMBO J. , vol.6 , pp. 605-610
    • Kraus, M.H.1    Popescu, N.C.2    Amsbaugh, S.C.3    King, C.R.4
  • 39
    • 0023304864 scopus 로고
    • Epidermal growth factor receptor gene expression in estrogen receptor-positive and negative human breast cancer cell lines
    • Davidson, N. E., Gelmann, E. P., Lippman, M. E , and Dickson, R E Epidermal growth factor receptor gene expression in estrogen receptor-positive and negative human breast cancer cell lines. Mol Endocrinol., 1: 216-223, 1987.
    • (1987) Mol Endocrinol. , vol.1 , pp. 216-223
    • Davidson, N.E.1    Gelmann, E.P.2    Lippman, M.E.3    Dickson, R.E.4
  • 40
    • 0025374582 scopus 로고
    • Hormonal modulatron of HER-2/neu protooncogene messenger ribonucleic acid and p185 protein expression in human breast cancer cell lines
    • Read, L. D., Keith, D , Jr, Slamon, D. J., and Kauenellenbogen, B. S. Hormonal modulatron of HER-2/neu protooncogene messenger ribonucleic acid and p185 protein expression in human breast cancer cell lines. Cancer Res., 50: 3947-3951, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 3947-3951
    • Read, L.D.1    Keith Jr., D.2    Slamon, D.J.3    Kauenellenbogen, B.S.4
  • 41
    • 0029029137 scopus 로고
    • Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin-like growth factor-1 in human mammary epithelial cells
    • Ram, T. G., Kokeny, K. E., Dilts, C. A., and Ethier, S. P. Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin-like growth factor-1 in human mammary epithelial cells. J. Cell. Physiol., 163: 589-596, 1995.
    • (1995) J. Cell. Physiol. , vol.163 , pp. 589-596
    • Ram, T.G.1    Kokeny, K.E.2    Dilts, C.A.3    Ethier, S.P.4
  • 43
    • 0021804944 scopus 로고
    • MDA-468, a human breast cancer cell line with high number of epidermal growth factor (EGF) receptors, has an amplified EGF receptor gene and is growth inhibited by egf
    • Filmus, J., Pollak, M. N., Cailleau, R., and Buick, R. N. MDA-468, a human breast cancer cell line with high number of epidermal growth factor (EGF) receptors, has an amplified EGF receptor gene and is growth inhibited by egf Biochem. Biophys. Res. Commun., 128. 898-905, 1985.
    • (1985) Biochem. Biophys. Res. Commun. , vol.128 , pp. 898-905
    • Filmus, J.1    Pollak, M.N.2    Cailleau, R.3    Buick, R.N.4
  • 44
    • 0019861187 scopus 로고
    • Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells
    • Gill, G. N , and Lazar, C. S. Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells. Nature (Lond.), 295. 305-307, 1981.
    • (1981) Nature (Lond.) , vol.295 , pp. 305-307
    • Gill, G.N.1    Lazar, C.S.2
  • 45
    • 0020039865 scopus 로고
    • Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture
    • Barnes, D W Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture. J. Cell Biol., 93: 1-4, 1982.
    • (1982) J. Cell Biol. , vol.93 , pp. 1-4
    • Barnes, D.W.1
  • 48
    • 0028077047 scopus 로고
    • Epidermal growth factor-dependent association of phosphatidylinositol 3-kinase with the erbB3 gene product
    • Kim, H. H., Sierke, S L., and Koland, J. G. Epidermal growth factor-dependent association of phosphatidylinositol 3-kinase with the erbB3 gene product. J. Biol. Chem., 269: 24747-24755, 1994
    • (1994) J. Biol. Chem. , vol.269 , pp. 24747-24755
    • Kim, H.H.1    Sierke, S.L.2    Koland, J.G.3
  • 49
    • 0028302018 scopus 로고
    • ErbB3 is involved in activation of phosphatidylmositol 3-kinase by epidermal growth factor
    • Soltoff, S. P., Carraway, K. L , Prigent, S. A., Gullick, W. G., and Cantley, L. C. ErbB3 is involved in activation of phosphatidylmositol 3-kinase by epidermal growth factor. Mol. Cell. Biol., 14: 3550-3558, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3550-3558
    • Soltoff, S.P.1    Carraway, K.L.2    Prigent, S.A.3    Gullick, W.G.4    Cantley, L.C.5
  • 51
    • 0028785406 scopus 로고
    • Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
    • Gassmann, M., Casagranda, F., Onoli, D., Simon, H., Lai, C., Klein, R., and Lemke, G Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature (Lond), 378. 390-394, 1995.
    • (1995) Nature (Lond) , vol.378 , pp. 390-394
    • Gassmann, M.1    Casagranda, F.2    Onoli, D.3    Simon, H.4    Lai, C.5    Klein, R.6    Lemke, G.7
  • 52
    • 0028823802 scopus 로고
    • Neu differentiation factor activation of ErbB-3 and ErbB-4 is cell specific and displays a differential requirement for ErbB-2
    • Beerli, R., Graus-Porta, D., Woods-Cook, K., Chen, X , Yarden, Y., and Hynes, N. E. Neu differentiation factor activation of ErbB-3 and ErbB-4 is cell specific and displays a differential requirement for ErbB-2 Mol. Cell. Biol., 15. 6496-6505, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6496-6505
    • Beerli, R.1    Graus-Porta, D.2    Woods-Cook, K.3    Chen, X.4    Yarden, Y.5    Hynes, N.E.6
  • 53
    • 0029053716 scopus 로고
    • Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas
    • Alimandi, M., Romaao, A., Cuna, M. C., Muraro, R , Fedi, P., Aaronson, S. A., Di Fiore, P. P., and Kraus, M. H. Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas Oncogene, 10: 1813-1821, 1995.
    • (1995) Oncogene , vol.10 , pp. 1813-1821
    • Alimandi, M.1    Romaao, A.2    Cuna, M.C.3    Muraro, R.4    Fedi, P.5    Aaronson, S.A.6    Di Fiore, P.P.7    Kraus, M.H.8
  • 54
    • 0028157728 scopus 로고
    • The IRS-1 signaling system
    • White, M. F. The IRS-1 signaling system. Curr. Opin. Genet. Dev . 4: 47-54, 1994.
    • (1994) Curr. Opin. Genet. Dev . , vol.4 , pp. 47-54
    • White, M.F.1
  • 55
    • 0029162564 scopus 로고
    • Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3
    • Wallasch, C., Weiss, F. U., Niederfellner, G., Jallal, B , Issing, W., and Ullrich, A. Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3. EMBO J., 14: 4267-4275, 1995.
    • (1995) EMBO J. , vol.14 , pp. 4267-4275
    • Wallasch, C.1    Weiss, F.U.2    Niederfellner, G.3    Jallal, B.4    Issing, W.5    Ullrich, A.6
  • 57
    • 0028796895 scopus 로고
    • NDF/heregulin activates MAP kinase and p70/p85 S6 kinase during proliferation or differentiation of mammary epithelial cells
    • Marte, B M , Graus-Porta, D., Jeschke, M., Fabbro, D., Hynes, N. E., and Taverna, D. NDF/heregulin activates MAP kinase and p70/p85 S6 kinase during proliferation or differentiation of mammary epithelial cells. Oncogene, 10: 167-175, 1995.
    • (1995) Oncogene , vol.10 , pp. 167-175
    • Marte, B.M.1    Graus-Porta, D.2    Jeschke, M.3    Fabbro, D.4    Hynes, N.E.5    Taverna, D.6
  • 58
    • 0019394886 scopus 로고
    • 3H]thymidine techniques to measure cell proliferation
    • 3H]thymidine techniques to measure cell proliferation Cell Tissue Kinet. 14: 111-120, 1981.
    • (1981) Cell Tissue Kinet. , vol.14 , pp. 111-120
    • Maurer, H.R.1
  • 59
    • 0018652015 scopus 로고
    • 3H]thymidine incorporation into DNA as an indicator of epidermal keratinocyte proliferation in vitro
    • 3H]thymidine incorporation into DNA as an indicator of epidermal keratinocyte proliferation in vitro Cell Tissue Kinet., 12: 605-614, 1979.
    • (1979) Cell Tissue Kinet. , vol.12 , pp. 605-614
    • Davison, P.1    Liu, S.2    Karasek, M.3
  • 61
    • 0026739541 scopus 로고
    • Transformation mediated by the human HER-2 gene independent of the epidermal growth factor receptor
    • Chazin, V. R., Kaleko, M., Miller, A D., and Slamon, D. J. Transformation mediated by the human HER-2 gene independent of the epidermal growth factor receptor. Oncogene. 7: 1859-1866, 1992.
    • (1992) Oncogene , vol.7 , pp. 1859-1866
    • Chazin, V.R.1    Kaleko, M.2    Miller, A.D.3    Slamon, D.J.4
  • 62
    • 0022217557 scopus 로고
    • Epidermal growth factor stimulates the growth of A431 tumours in athymic mice
    • Ginsburg, E., and Vonderhaar, B K. Epidermal growth factor stimulates the growth of A431 tumours in athymic mice. Cancer Lett. 28: 143-150, 1985.
    • (1985) Cancer Lett. , vol.28 , pp. 143-150
    • Ginsburg, E.1    Vonderhaar, B.K.2
  • 63
    • 0023506130 scopus 로고
    • Stimulation by EGF of the growth of EGF receptor-hyperproducmg tumour cells in athymic mice
    • Ozawa, S., Ueda, M , Ando, N., Abe, O., Hirai, M., and Shimizu, N. Stimulation by EGF of the growth of EGF receptor-hyperproducmg tumour cells in athymic mice. Int. J. Cancer. 40: 706-710, 1987
    • (1987) Int. J. Cancer. , vol.40 , pp. 706-710
    • Ozawa, S.1    Ueda, M.2    Ando, N.3    Abe, O.4    Hirai, M.5    Shimizu, N.6
  • 64
    • 9844244670 scopus 로고
    • Loss of heregulin expression is associated with malignancy
    • Park, J. W , Slamon, D , and Shepard, H. M. Loss of heregulin expression is associated with malignancy. Proc. Am. Assoc. Cancer Res., 84- 3107, 1993.
    • (1993) Proc. Am. Assoc. Cancer Res. , vol.84 , pp. 3107
    • Park, J.W.1    Slamon, D.2    Shepard, H.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.