Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence

Cancer Research

Volumn 56, Issue 2, 1996, Pages 393-401

  Saleh, Mary ^a   Stacker, Steven A ^b   Wilks, Andrew F ^b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; ASTROCYTOMA; CANCER GROWTH; CARCINOGENESIS; ENDOTHELIUM CELL; GENE EXPRESSION; GENE THERAPY; GLIOMA CELL; GROWTH INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR VOLUME; VASCULAR ENDOTHELIUM;

ANIMALS; BASE SEQUENCE; BRAIN NEOPLASMS; CELL DIVISION; CELL HYPOXIA; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; FEMALE; GENE THERAPY; GLIOMA; LYMPHOKINES; MALE; MICE; MICE, NUDE; MOLECULAR SEQUENCE DATA; NECROSIS; NEOVASCULARIZATION, PATHOLOGIC; OLIGONUCLEOTIDES, ANTISENSE; RATS; TRANSFECTION; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0030029271     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Leung, D W., Cachianes, G., Kuang, W. J., Goeddel, D. V., and Ferrara, N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science (Washington DC), 246: 1306-1309, 1989.
2. Shweiki, D., Itin, A., Soffer, D., and Keshet, E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature (Lond.), 359: 843-845, 1992.
3. Keck, P. J , Hauser, S D., Krivi, G , Sanzo, K., Warren, T , Feder, J., and Connolly, D T Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science (Washington DC), 246: 1309-1312, 1989.
4. Houck, K. A. Ferrara, J N., Winer, J., Cachianes, G., Li, B , and Leung, D. W The vascular endothelial growth factor family identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol Endocrinol. 5: 1806-1814, 1991
5. De Vries, C , Escobedo, J. A., Ueno, H., Houck, K., Ferrara, N., and Williams, L. T. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science (Washington DC), 255: 989-991, 1992.
6. Millauer, B., Wizigmann Voos, S., Schnurch, H., Martinez, R., Moller, N. P., Risau, W , and Ullrich, A High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell. 72: 835-846, 1993.
7. Oelrichs, R. B., Reid, H. H., Bernard, O., Ziemiecki, A., and Wilks, A. F. NYK/ FLK-1, a putative receptor protein tyrosine kinase isolated from E10 embryonic neuroepithelium is expressed in endothelial cells of the developing embryo. Oncogene, 8: 11-18, 1993.
8. Terman, B. I., Dougher-Vermazen, M., Carrion, M. E , Dimitrov, D , Armellino, D C , Gospodarowicz, D., and Bohlen, P Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem. Biophys Res. Commun. 187: 1579-1586, 1993.
9. Tischer, E , Gospodarowicz, D., Mitchell, R . Silva, M., Schilling, J., Lau, K., Crisp, T., Fiddes, J. C., and Abraham, J. A. Vascular endothelial growth factor: a new member of the platelet-derived growth factor gene family. Biochem. Biophys. Res. Commun , 165: 1198-1206, 1989.
10. Conn, G., Bayne, M L , Soderman, D. D., Kwok, P. W., Sullivan, K. A., Palisi, T. M., Hope, D. A., and Thomas, K. A. Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor. Proc. Natl. Acad Sci. USA, 87: 2628-2632, 1990.
11. Breier, G., Albrecht, U., Sterrer, S., and Risau, W. Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation. Development (Camb ), 114: 521-532, 1992.
12. Plate, K. H , Breier. G., Weich, H. A., and Risau, W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature (Lond.), 359, 845-848, 1992.
13. Plate. K. H . Breier, G., Weich, H. A., and Risau, W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature (Lond.), 359: 845-848, 1993.
14. Shweiki, D , Itin, A., Soffer, D., and Keshet, E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature [Lond.), 359 843-845, 1993
15. Kim, K. J., Li, B , Winer, J , Armanini, M., Gillett, N., Phillips, H. S., and Ferrara, N Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature (Lond.), 362, 841-844, 1993.
16. Maullauer, B., Shawver, L K , Plate, K. L., Risau, W , and Ullrich, A. Glioblastoma growth inhibited in vivo by a dominant-negative Flk1- mutant. Nature (Lond.), 367: 576-579, 1994.
17. Kaye, A. H., and Hill, J. S Photodynamic therapy of brain tumors. Ann. Acad. Med. Singapore. 22- 470-481, 1993.
18. Woodburn, K. W , Hill, J. S., Stylli, S., Kaye, A. H., Reiss, J. A., and Phillips, D R. Evaluation of a morpholinothiolporphyrin for use in photodynamic therapy. Br. J. Cancer, 70: 398-400, 1994
19. Gillaspy, G. E , Mapstone, T. B., Samols, D., and Goldthwait, D. A. Transcriptional patterns of growth factors and proto-oncogenes in human glioblastomas and normal glial cells Cancer Lett , 65: 55-60, 1992
20. Pedersen, P , Ness, G. O., Engerbraaten, O , Bjerkvig, R., Lillehaug, J H., and Laerum, O D Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF-α, bFGF, IL-2] on glioma spheroid srowdv migration and invasion. Int. J. Cancer. 56: 255-261, 1994.
21. Brem, S., Cotran, R . and Folkman, J. Tumour angiogenesis, a quantitative method for histological grading J. Natl Cancer Inst., 48: 347-356, 1972.
22. Kaye, A. H , Morstyn, G., Gardner, I., and Pyke, K. Development of a xenograft glioma model in mouse brain Cancer Res., 46- 1367-1373 1986.
23. Mizushima, S., and Nagatal S. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res, 18: 5322, 1990.
24. Graham, F. L., and Eb, A. J. V. Transformation of rat cells by DNA of human adenovirus 5. Virology, 54- 536-539, 1973.
25. Church, G M., and Gilbert, W. Genomic Sequencing Proc Natl. Acad. Sci. USA, 81: 1991-1995, 1984.
26. Feinberg, A P , and Vogelstein, B. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal Biochem., 137, 266-267, 1984.
27. Chirgwin, J. M., Przybyla, A. E., McDonald, F. J., and Rutter, W. J Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry, 8, 5294-5299, 1979.
28. Minchenko, A., Salceda, S., Bauer, T., and Caro, J. Hypoxia regulatory elements of the human vascular endothelial growth factor gene. Cell. Mol. Biol Res., 40: 35-39, 1994.
29. Folkman, J. Anti-angiogenesis: new concepts of therapy of solid tumors. Ann. Surg., 175: 409-416, 1972.
30. Roberts, G., and Bevilacqua, M P. Vascular endothelial growth factor inhibits E-selectin and VCAM expression m vitro and in vivo. J Cell. Biochem. Suppl., 18a: EZ312, 1994
31. Brown, L. F, Berse, B , Jackman, R. W., Tognazzi, K., Manseau, E. J., Senger, D. R., and Dvorak, H. F. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res., 53 4727-4735, 1993