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Volumn 22, Issue 7, 2000, Pages 646-656

The role of interleukin-13 in infectious diseases and allergy

Author keywords

[No Author keywords available]

Indexed keywords

IL13RA1 PROTEIN, HUMAN; IL13RA1 PROTEIN, MOUSE; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR; INTERLEUKIN 13 RECEPTOR ALPHA1; INTERLEUKIN 4; INTERLEUKIN RECEPTOR;

EID: 0033949735     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-1878(200007)22:7<646::AID-BIES7>3.0.CO;2-9     Document Type: Review
Times cited : (122)

References (88)
  • 2
    • 0028176655 scopus 로고
    • Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells
    • Zurawski G, de VJ. Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. Immunol Today 1994;15: 19-26.
    • (1994) Immunol Today , vol.15 , pp. 19-26
    • Zurawski, G.1    De, V.J.2
  • 4
    • 0032909720 scopus 로고    scopus 로고
    • IL-13 production by NK cells: IL-13-producing NK and T cells are present in vivo in the absence of IFN-γ
    • Hoshino T, Winkler-Pickett RT, Mason AT, Ortaldo JR, Young HA. IL-13 production by NK cells: IL-13-producing NK and T cells are present in vivo in the absence of IFN-γ. J Immunol 1999;162:51-59.
    • (1999) J Immunol , vol.162 , pp. 51-59
    • Hoshino, T.1    Winkler-Pickett, R.T.2    Mason, A.T.3    Ortaldo, J.R.4    Young, H.A.5
  • 5
    • 0026731478 scopus 로고
    • Conversion of human interleukin-4 into a high affinity antagonist by a single amino acid replacement
    • Kruse N, Tony HP, Sebald W. Conversion of human interleukin-4 into a high affinity antagonist by a single amino acid replacement. EMBO J 1992;11:3237-3244.
    • (1992) EMBO J , vol.11 , pp. 3237-3244
    • Kruse, N.1    Tony, H.P.2    Sebald, W.3
  • 6
    • 0027435159 scopus 로고
    • An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: Support for a common component shared by IL-4 and IL-13 receptors
    • Aversa G, Punnonen J, Cocks BG, de Waal Malefyt R, Vega FJ, Zurawski SM, Zurawski G, de Vries JE. An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptors. J Exp Med 1993;178: 2213-2218.
    • (1993) J Exp Med , vol.178 , pp. 2213-2218
    • Aversa, G.1    Punnonen, J.2    Cocks, B.G.3    De Waal Malefyt, R.4    Vega, F.J.5    Zurawski, S.M.6    Zurawski, G.7    De Vries, J.E.8
  • 7
    • 0028917463 scopus 로고
    • Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common gamma chain shared by receptors for interleukins 2, 4, 7, 9, and 15
    • Obiri NI, Debinski W, Leonard WJ, Puri RK. Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common gamma chain shared by receptors for interleukins 2, 4, 7, 9, and 15. J Biol Chem 1995;270:8797-8804.
    • (1995) J Biol Chem , vol.270 , pp. 8797-8804
    • Obiri, N.I.1    Debinski, W.2    Leonard, W.J.3    Puri, R.K.4
  • 8
    • 0031033551 scopus 로고    scopus 로고
    • X-SCID B cell responses to interleukin-4 and interleukin-13 are mediated by a receptor complex that includes the interleukin-4 receptor alpha chain (p140) but not the gamma c chain
    • Matthews DJ, Hibbert L, Friedrich K, Minty A, Callard RE. X-SCID B cell responses to interleukin-4 and interleukin-13 are mediated by a receptor complex that includes the interleukin-4 receptor alpha chain (p140) but not the gamma c chain. Eur J Immunol 1997;27:116-121.
    • (1997) Eur J Immunol , vol.27 , pp. 116-121
    • Matthews, D.J.1    Hibbert, L.2    Friedrich, K.3    Minty, A.4    Callard, R.E.5
  • 9
    • 15444343191 scopus 로고    scopus 로고
    • Mouse macrophage development in the absence of the common gamma chain: Defining receptor complexes responsible for IL-4 and IL-13 signaling
    • Andersson A, Grunewald SM, Duschl A, Fischer A, DiSanto JP. Mouse macrophage development in the absence of the common gamma chain: defining receptor complexes responsible for IL-4 and IL-13 signaling. Eur J Immunol 1997;27:1762-1768.
    • (1997) Eur J Immunol , vol.27 , pp. 1762-1768
    • Andersson, A.1    Grunewald, S.M.2    Duschl, A.3    Fischer, A.4    Disanto, J.P.5
  • 10
    • 0028000624 scopus 로고
    • Interleukin-13 inhibits the proliferation of normal and leukemic human B-cell precursors
    • Renard N, Duvert V, Banchereau J, Saeland S. Interleukin-13 inhibits the proliferation of normal and leukemic human B-cell precursors. Blood 1994;84:2253-2260.
    • (1994) Blood , vol.84 , pp. 2253-2260
    • Renard, N.1    Duvert, V.2    Banchereau, J.3    Saeland, S.4
  • 11
    • 0030068217 scopus 로고    scopus 로고
    • Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor
    • Hilton DJ, Zhang JG, Metcalf D, Alexander WS, Nicola NA, Willson TA. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc Natl Acad Sci USA 1996;93:497-501.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 497-501
    • Hilton, D.J.1    Zhang, J.G.2    Metcalf, D.3    Alexander, W.S.4    Nicola, N.A.5    Willson, T.A.6
  • 12
    • 10544246077 scopus 로고    scopus 로고
    • CDNA cloning and characterization of the human interleukin 13 receptor alpha chain
    • Aman MJ, Tayebi N, Obiri NI, Puri RK, Modi WS, Leonard WJ. cDNA cloning and characterization of the human interleukin 13 receptor alpha chain. J Biol Chem 1996;271:29265-29270.
    • (1996) J Biol Chem , vol.271 , pp. 29265-29270
    • Aman, M.J.1    Tayebi, N.2    Obiri, N.I.3    Puri, R.K.4    Modi, W.S.5    Leonard, W.J.6
  • 13
    • 0029927153 scopus 로고    scopus 로고
    • Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain
    • Caput D, Laurent P, Kaghad M, Lelias JM, Lefort S, Vita N, Ferrara P. Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain J Biol Chem 1996;271:16921-16926.
    • (1996) J Biol Chem , vol.271 , pp. 16921-16926
    • Caput, D.1    Laurent, P.2    Kaghad, M.3    Lelias, J.M.4    Lefort, S.5    Vita, N.6    Ferrara, P.7
  • 14
    • 0033564686 scopus 로고    scopus 로고
    • Differences between IL-4 and IL-4Rα deficient mice in chronic Leishmaniasis reveal a protective role for IL-13 receptor signalling
    • Mohrs M, Lederman B, Koehler G, Dorfmueller A, Gessner A, Brombacher F. Differences between IL-4 and IL-4Rα deficient mice in chronic Leishmaniasis reveal a protective role for IL-13 receptor signalling. J Immunol 1999;162:7302.
    • (1999) J Immunol , vol.162 , pp. 7302
    • Mohrs, M.1    Lederman, B.2    Koehler, G.3    Dorfmueller, A.4    Gessner, A.5    Brombacher, F.6
  • 15
    • 0030587813 scopus 로고    scopus 로고
    • Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice
    • Takeda K, Kamanaka M, Tanaka T, Kishimoto T, Akira S. Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice. J Immunol 1996;157:3220-3222.
    • (1996) J Immunol , vol.157 , pp. 3220-3222
    • Takeda, K.1    Kamanaka, M.2    Tanaka, T.3    Kishimoto, T.4    Akira, S.5
  • 18
    • 0030975719 scopus 로고    scopus 로고
    • Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned II-13 receptor and II-4 receptor alpha-chains
    • Zhang JG, Hilton DJ, Willson TA, McFarlane C, Roberts BA, Moritz RL, Simpson RJ, Alexander WS, Metcalf D, Nicola NA. Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned II-13 receptor and II-4 receptor alpha-chains. J Biol Chem 1997;272: 9474-9480.
    • (1997) J Biol Chem , vol.272 , pp. 9474-9480
    • Zhang, J.G.1    Hilton, D.J.2    Willson, T.A.3    McFarlane, C.4    Roberts, B.A.5    Moritz, R.L.6    Simpson, R.J.7    Alexander, W.S.8    Metcalf, D.9    Nicola, N.A.10
  • 19
    • 0033024881 scopus 로고    scopus 로고
    • Enhancement of human IL-4 activity by soluble IL-4 receptors in vitro
    • Jurg T, Wagner K, Neumann C, Heusser CH. Enhancement of human IL-4 activity by soluble IL-4 receptors in vitro. Eur J Immunol 1999;29: 864-871.
    • (1999) Eur J Immunol , vol.29 , pp. 864-871
    • Jurg, T.1    Wagner, K.2    Neumann, C.3    Heusser, C.H.4
  • 22
    • 0031571205 scopus 로고    scopus 로고
    • Characterisation of IL-12 receptor β1 chain (IL-12Rβ1)-deficient mice
    • Wu CY, Ferrante J, Gately MK, Magram J. Characterisation of IL-12 receptor β1 chain (IL-12Rβ1)-deficient mice. J Immunol 1997;159: 1658-1665.
    • (1997) J Immunol , vol.159 , pp. 1658-1665
    • Wu, C.Y.1    Ferrante, J.2    Gately, M.K.3    Magram, J.4
  • 26
    • 0029796717 scopus 로고    scopus 로고
    • In interleukin-4-deficient mice, alum not only generates T helper 1 responses equivalent to freund's complete adjuvant, but continues to induce T helper 2 cytokine production
    • Brewer JM, Conacher M, Satoskar A, Bluethmann H, Alexander J. In interleukin-4-deficient mice, alum not only generates T helper 1 responses equivalent to freund's complete adjuvant, but continues to induce T helper 2 cytokine production. Eur J Immunol 1996;26:2062-2066.
    • (1996) Eur J Immunol , vol.26 , pp. 2062-2066
    • Brewer, J.M.1    Conacher, M.2    Satoskar, A.3    Bluethmann, H.4    Alexander, J.5
  • 27
    • 0032554784 scopus 로고    scopus 로고
    • Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses
    • Barner M, Mohrs M, Brombacher F, Kopf M. Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses. Curr Biol 1998;8:669-672.
    • (1998) Curr Biol , vol.8 , pp. 669-672
    • Barner, M.1    Mohrs, M.2    Brombacher, F.3    Kopf, M.4
  • 29
    • 0033577811 scopus 로고    scopus 로고
    • Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses
    • McKenzie GJ, Fallon P, Emson CL, Grencis R, McKenzie ANJ. Simultaneous disruption of Interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses. J Exp Med 1999;189: 1565-1572.
    • (1999) J Exp Med , vol.189 , pp. 1565-1572
    • McKenzie, G.J.1    Fallon, P.2    Emson, C.L.3    Grencis, R.4    McKenzie, A.N.J.5
  • 32
    • 0031852973 scopus 로고    scopus 로고
    • Interleukin (IL)-4-independent induction of immunoglobulin (Ig)E and perturbation of T cell development in transgenic mice expressing IL-13
    • Emson CL, Bell SE, Jones A, Wisden W, McKenzie AN. Interleukin (IL)-4-independent induction of immunoglobulin (Ig)E and perturbation of T cell development in transgenic mice expressing IL-13. J Exp Med 1998;188:399-404.
    • (1998) J Exp Med , vol.188 , pp. 399-404
    • Emson, C.L.1    Bell, S.E.2    Jones, A.3    Wisden, W.4    McKenzie, A.N.5
  • 33
    • 0033555809 scopus 로고    scopus 로고
    • IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs
    • Chiaramonte MG, Schopf LR, Neben TY, Cheever AW, Donaldson DD, Wynn TA. IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs. J Immunol 1999;162:920-930.
    • (1999) J Immunol , vol.162 , pp. 920-930
    • Chiaramonte, M.G.1    Schopf, L.R.2    Neben, T.Y.3    Cheever, A.W.4    Donaldson, D.D.5    Wynn, T.A.6
  • 34
    • 0033153448 scopus 로고    scopus 로고
    • Leishmania major infection of inbred mice: Unmasking genetic determinants of infectious diseases
    • Fowell DJ, Locksley RM. Leishmania major infection of inbred mice: unmasking genetic determinants of infectious diseases. BioEssays 1999;21:510-518.
    • (1999) Bioessays , vol.21 , pp. 510-518
    • Fowell, D.J.1    Locksley, R.M.2
  • 36
    • 0024540908 scopus 로고
    • Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets
    • Heinzel FP, Sadick MD, Holaday BJ, Coffman RL, Locksley RM. Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. J Exp Med 1989;169:59-72.
    • (1989) J Exp Med , vol.169 , pp. 59-72
    • Heinzel, F.P.1    Sadick, M.D.2    Holaday, B.J.3    Coffman, R.L.4    Locksley, R.M.5
  • 37
    • 0030002111 scopus 로고    scopus 로고
    • Genetically resistan: Mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
    • Mattner F, Magram J, Ferrante J, Launois P, Di PK, Behin R, Gately MK, Louis JA, Alber G. Genetically resistan: mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur J Immunol 1996;26:1553-1559.
    • (1996) Eur J Immunol , vol.26 , pp. 1553-1559
    • Mattner, F.1    Magram, J.2    Ferrante, J.3    Launois, P.4    Di, P.K.5    Behin, R.6    Gately, M.K.7    Louis, J.A.8    Alber, G.9
  • 38
    • 0030023112 scopus 로고    scopus 로고
    • Susceptibility to leishmania major infection in interleukin-4-deficient mice
    • Noben-Trauth N, Kropf P, Muller I. Susceptibility to Leishmania major infection in interleukin-4-deficient mice. Science 1996;271: 987-990.
    • (1996) Science , vol.271 , pp. 987-990
    • Noben-Trauth, N.1    Kropf, P.2    Muller, I.3
  • 39
    • 0033563135 scopus 로고    scopus 로고
    • IL-4 and IL-4 receptor deficient Balb/c mice reveal differences in susceptibility to Leishmania major parasite substrans
    • Noben-Trauth N, Paul WE, Sacks DL. IL-4 and IL-4 receptor deficient Balb/c mice reveal differences in susceptibility to Leishmania major parasite substrans. J Immunol 1999;162:6132-6140.
    • (1999) J Immunol , vol.162 , pp. 6132-6140
    • Noben-Trauth, N.1    Paul, W.E.2    Sacks, D.L.3
  • 41
    • 0034106507 scopus 로고    scopus 로고
    • IL-4 receptor alpha deficient BALB/c mice show an unimpaired T helper2 polarization in response to leishmania major infection
    • in press
    • Mohrs M, Brombacher F, IL-4 receptor alpha deficient BALB/c mice show an unimpaired T helper2 polarization in response to Leishmania major infection. Infect Immun 2000; in press.
    • (2000) Infect Immun
    • Mohrs, M.1    Brombacher, F.2
  • 42
    • 0032729433 scopus 로고    scopus 로고
    • Expression of Th2 cytokines and the stable Th2 marker ST2L in the absence of IL-4 during leishmania major infection
    • Kropf P, Schopf L, Chung C, Xu D, Liw FY, Sypek J, Muller I. Expression of Th2 cytokines and the stable Th2 marker ST2L in the absence of IL-4 during Leishmania major infection. Eur J Immunol 1999;29:3621-3628.
    • (1999) Eur J Immunol , vol.29 , pp. 3621-3628
    • Kropf, P.1    Schopf, L.2    Chung, C.3    Xu, D.4    Liw, F.Y.5    Sypek, J.6    Muller, I.7
  • 44
    • 0028787484 scopus 로고
    • Disruption of the murine interleukin-4 gene inhibits disease progression during Leishmania mexicana infection but does not increase control of Leishmania donovan infection
    • Satoskar A, Bluethmann H, Alexander J. Disruption of the murine interleukin-4 gene inhibits disease progression during Leishmania mexicana infection but does not increase control of Leishmania donovan infection. Infect Immun 1995;63:4894-4899.
    • (1995) Infect Immun , vol.63 , pp. 4894-4899
    • Satoskar, A.1    Bluethmann, H.2    Alexander, J.3
  • 45
    • 0031573080 scopus 로고    scopus 로고
    • SCID mice reconstituted with IL-4-deficient lymphocytes, but not immunocompetent lymphocytes, are resistant to cutaneous leishmaniasis
    • Satoskar A, Brombacher F, Dai WJ, McInnes I, Liew FY, Alexander J, Walker W. SCID mice reconstituted with IL-4-deficient lymphocytes, but not immunocompetent lymphocytes, are resistant to cutaneous leishmaniasis. J Immunol 1997;159:5005-5013.
    • (1997) J Immunol , vol.159 , pp. 5005-5013
    • Satoskar, A.1    Brombacher, F.2    Dai, W.J.3    McInnes, I.4    Liew, F.Y.5    Alexander, J.6    Walker, W.7
  • 48
    • 0029025415 scopus 로고
    • Infection of IL-4-deficient mice with the parasitic nematode Brugia malayi demonstrates that host resistance is not dependent on a T helper 2-dominated immune response
    • Lawrence RA, Allen JE, Gregory WF, Kopf M, Maizels RM. Infection of IL-4-deficient mice with the parasitic nematode Brugia malayi demonstrates that host resistance is not dependent on a T helper 2-dominated immune response. J Immunol 1995;154:5995-6001.
    • (1995) J Immunol , vol.154 , pp. 5995-6001
    • Lawrence, R.A.1    Allen, J.E.2    Gregory, W.F.3    Kopf, M.4    Maizels, R.M.5
  • 49
    • 0030272482 scopus 로고    scopus 로고
    • Nippostrongylus brasiliensis: Cytokine responses and nematode expulsion in normal and IL-4 deficient mice
    • Lawrence RA, Gray CA, Osborne J, Maizels RM. Nippostrongylus brasiliensis: cytokine responses and nematode expulsion in normal and IL-4 deficient mice. Exp Parasit 1997;84:65.
    • (1997) Exp Parasit , vol.84 , pp. 65
    • Lawrence, R.A.1    Gray, C.A.2    Osborne, J.3    Maizels, R.M.4
  • 50
    • 0030931043 scopus 로고    scopus 로고
    • An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice
    • Noben-Trauth N, Shultz LD, Brombacher F, Urban JJ, Gu H, Paul WE. An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice. Proc Natl Acad Sci USA 1997;94:10838-10843.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10838-10843
    • Noben-Trauth, N.1    Shultz, L.D.2    Brombacher, F.3    Urban, J.J.4    Gu, H.5    Paul, W.E.6
  • 52
    • 0032510452 scopus 로고    scopus 로고
    • A distinct role for interleukin-13 in Th2-cell-mediated immune responses
    • McKenzie GJ, Bancroft A, Grencis RK, McKenzie AN. A distinct role for interleukin-13 in Th2-cell-mediated immune responses. Curr Biol 1998;8: 339-342.
    • (1998) Curr Biol , vol.8 , pp. 339-342
    • McKenzie, G.J.1    Bancroft, A.2    Grencis, R.K.3    McKenzie, A.N.4
  • 53
    • 0032007351 scopus 로고    scopus 로고
    • IL-13, IL-4Ralpna, and STAT6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis
    • Urban JJ, Noben TN, Donaldson DD, Madden KB, Morris SC, Collins M, Finkelman FD. IL-13, IL-4Ralpna, and STAT6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity 1998;8:255-264.
    • (1998) Immunity , vol.8 , pp. 255-264
    • Urban, J.J.1    Noben, T.N.2    Donaldson, D.D.3    Madden, K.B.4    Morris, S.C.5    Collins, M.6    Finkelman, F.D.7
  • 54
    • 0032055579 scopus 로고    scopus 로고
    • A critical role for IL-13 in resistance to intestinal nematode infection
    • Bancroft AJ, McKenzie ANJ, Grencis RK. A critical role for IL-13 in resistance to intestinal nematode infection J Immunol 1998;160:3453-3461.
    • (1998) J Immunol , vol.160 , pp. 3453-3461
    • Bancroft, A.J.1    McKenzie, A.N.J.2    Grencis, R.K.3
  • 55
    • 0031570939 scopus 로고    scopus 로고
    • IL-4 protects against TNF-alpha-mediated cachexia and death during acute schistosomiasis
    • Brunet LR, Finkelman FD, Oneever AW, Kopf MA, Pearce EJ. IL-4 protects against TNF-alpha-mediated cachexia and death during acute schistosomiasis. Eur J Immunol 1997;159:777-785.
    • (1997) Eur J Immunol , vol.159 , pp. 777-785
    • Brunet, L.R.1    Finkelman, F.D.2    Oneever, A.W.3    Kopf, M.A.4    Pearce, E.J.5
  • 56
    • 0032519993 scopus 로고    scopus 로고
    • Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response
    • Kaplan MH, Whitfield JR, Boros DL Grusby MJ. Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response. J Immunol 1998;160:1850.
    • (1998) J Immunol , vol.160 , pp. 1850
    • Kaplan, M.H.1    Whitfield, J.R.2    Boros, D.L.3    Grusby, M.J.4
  • 57
    • 0028363023 scopus 로고
    • Anti-IL-4 treatment of schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis
    • Cheever AW, Williams ME, Wynn TA, Finkelman FD, Seder RA, Cox TM, Hieny S, Caspar P, Sher A. Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis. J Immunol 1994;153:753-759.
    • (1994) J Immunol , vol.153 , pp. 753-759
    • Cheever, A.W.1    Williams, M.E.2    Wynn, T.A.3    Finkelman, F.D.4    Seder, R.A.5    Cox, T.M.6    Hieny, S.7    Caspar, P.8    Sher, A.9
  • 58
    • 0030588570 scopus 로고    scopus 로고
    • The granulomatous response in murine schistosomiasis mansoni does not switch to Th1 in IL-4-deficient C57BL/6 mice
    • Metwali A, Elliolt D, Blum AM, Li J, Sandor M, Lynch R, Noben TN, Weinstock JV. The granulomatous response in murine Schistosomiasis mansoni does not switch to Th1 in IL-4-deficient C57BL/6 mice J Immunol 1996;157:4546-4553.
    • (1996) J Immunol , vol.157 , pp. 4546-4553
    • Metwali, A.1    Elliolt, D.2    Blum, A.M.3    Li, J.4    Sandor, M.5    Lynch, R.6    Noben, T.N.7    Weinstock, J.V.8
  • 60
    • 0033168893 scopus 로고    scopus 로고
    • Schistosome-infected IL-4 receptor knockout (KO) mice. in contrast to IL-4 ko mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile
    • Jankovic D, Kullberg MC Noben TN, Caspar P, Ward JM, Cheever AW, Paul WE, Sher A. Schistosome-Infected IL-4 Receptor Knockout (KO) Mice. in Contrast to IL-4 KO Mice, Fail to Develop Granulomatous Pathology While Maintaining the Same Lymphokine Expression Profile. J Immunol 1999;163:337-342.
    • (1999) J Immunol , vol.163 , pp. 337-342
    • Jankovic, D.1    Kullberg, M.C.2    Noben, T.N.3    Caspar, P.4    Ward, J.M.5    Cheever, A.W.6    Paul, W.E.7    Sher, A.8
  • 61
    • 0032697042 scopus 로고    scopus 로고
    • An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response
    • Chiaramonte MG, Donaldson DD, Cheever AW, Wynn TA. An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response. J Clin Invest 1999;104 777-785.
    • (1999) J Clin Invest , vol.104 , pp. 777-785
    • Chiaramonte, M.G.1    Donaldson, D.D.2    Cheever, A.W.3    Wynn, T.A.4
  • 62
    • 0026333085 scopus 로고
    • Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity
    • Walker C, Kaeg MK, Braun P, Blaser K. Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity. J Allergy Clin Immunol 1991;88:935-942.
    • (1991) J Allergy Clin Immunol , vol.88 , pp. 935-942
    • Walker, C.1    Kaeg, M.K.2    Braun, P.3    Blaser, K.4
  • 64
    • 0028432404 scopus 로고
    • Interleukin-4-dependent pulmonary eosinophil infiltration in a murine model of asthma
    • Lukacs NW, Strieter RM, Chensue SW, Kunkel SL. Interleukin-4-dependent pulmonary eosinophil infiltration in a murine model of asthma. Am J Respir Cell Mol Biol 1994;10:526-532.
    • (1994) Am J Respir Cell Mol Biol , vol.10 , pp. 526-532
    • Lukacs, N.W.1    Strieter, R.M.2    Chensue, S.W.3    Kunkel, S.L.4
  • 68
    • 0032522641 scopus 로고    scopus 로고
    • An antagonistic IL-4 mutant prevents type I allergy in the mouse: Inhibition of the IL-4/IL-13 receptor system completely abrogates humoral immune response to allergen and development of allergic symptoms in vivo
    • Grunewald SM, Werthmann A, Schnarr B, Klein CE, Brocker EB, Mohrs M, Brombacher F, Sebald W, Duschl A. An antagonistic IL-4 mutant prevents type I allergy in the mouse: inhibition of the IL-4/IL-13 receptor system completely abrogates humoral immune response to allergen and development of allergic symptoms in vivo. J Immunol 1998;160: 4004-4009.
    • (1998) J Immunol , vol.160 , pp. 4004-4009
    • Grunewald, S.M.1    Werthmann, A.2    Schnarr, B.3    Klein, C.E.4    Brocker, E.B.5    Mohrs, M.6    Brombacher, F.7    Sebald, W.8    Duschl, A.9
  • 71
    • 0030028768 scopus 로고    scopus 로고
    • Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model
    • Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, Young IG. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model [see comments] J Exp Med 1996; 183:195-201.
    • (1996) J Exp Med , vol.183 , pp. 195-201
    • Foster, P.S.1    Hogan, S.P.2    Ramsay, A.J.3    Matthaei, K.I.4    Young, I.G.5
  • 73
    • 0030068235 scopus 로고    scopus 로고
    • Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity
    • May 5
    • Corry DB, Folkesson HG, Warnock ML, Erle DJ, Matthay MA, Wiener KJ, Locksley RM. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity [see comments] [published erratum appears in J Exp Med 1997 May 5;185(9): 1715] J Exp Med 1996;183:109-117.
    • (1997) J Exp Med , vol.185 , Issue.9 , pp. 1715
    • Corry, D.B.1    Folkesson, H.G.2    Warnock, M.L.3    Erle, D.J.4    Matthay, M.A.5    Wiener, K.J.6    Locksley, R.M.7
  • 74
    • 0030068235 scopus 로고    scopus 로고
    • Corry DB, Folkesson HG, Warnock ML, Erle DJ, Matthay MA, Wiener KJ, Locksley RM. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity [see comments] [published erratum appears in J Exp Med 1997 May 5;185(9): 1715] J Exp Med 1996;183:109-117.
    • (1996) J Exp Med , vol.183 , pp. 109-117
  • 75
    • 0031668493 scopus 로고    scopus 로고
    • Eosinophils are not required to induce airway hyperresponsiveness after nematode infection
    • Coyle AJ, Kohler G, Tsuyuki S, Brombacher F, Kopf M. Eosinophils are not required to induce airway hyperresponsiveness after nematode infection Eur J Immunol 1998;28:2640-2647.
    • (1998) Eur J Immunol , vol.28 , pp. 2640-2647
    • Coyle, A.J.1    Kohler, G.2    Tsuyuki, S.3    Brombacher, F.4    Kopf, M.5
  • 76
    • 0033562979 scopus 로고    scopus 로고
    • Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils
    • Cohn L, Homer RJ, MacLeod H, Mohrs M, Brombache F, Bottomly K. Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils. J Immunol 1999;162:6178-6183.
    • (1999) J Immunol , vol.162 , pp. 6178-6183
    • Cohn, L.1    Homer, R.J.2    Macleod, H.3    Mohrs, M.4    Brombache, F.5    Bottomly, K.6
  • 77
    • 0030878829 scopus 로고    scopus 로고
    • Complexity and redundancy in the pathogenesis of asthma: Reassessing the roles of mast cells and t cells
    • Galli SJ. Complexity and redundancy in the pathogenesis of asthma: reassessing the roles of mast cells and T cells. J Exp Med 1997;186: 343-347.
    • (1997) J Exp Med , vol.186 , pp. 343-347
    • Galli, S.J.1
  • 78
    • 0030999135 scopus 로고    scopus 로고
    • Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells
    • Pawankar R, Okuda M, Yssel H, Okumura K, Ra C. Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells [see comments]. J Clin Invest 1997;99:1492-1499.
    • (1997) J Clin Invest , vol.99 , pp. 1492-1499
    • Pawankar, R.1    Okuda, M.2    Yssel, H.3    Okumura, K.4    Ra, C.5
  • 79
    • 0031020812 scopus 로고    scopus 로고
    • Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice
    • Hamelmann E, Vella AT, Oshiba A, Kappler JW, Marrack P, Gelfand EW. Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice. Proc Natl Acad Sci USA 1997;94:1350-1355.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1350-1355
    • Hamelmann, E.1    Vella, A.T.2    Oshiba, A.3    Kappler, J.W.4    Marrack, P.5    Gelfand, E.W.6
  • 80
    • 0030810734 scopus 로고    scopus 로고
    • Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice
    • Takeda K, Hamelmann E, Joetham A, Shultz LD, Larsen GL, Irvin CG, Gelfand EW. Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice. J Exp Med 1997;186:449-454.
    • (1997) J Exp Med , vol.186 , pp. 449-454
    • Takeda, K.1    Hamelmann, E.2    Joetham, A.3    Shultz, L.D.4    Larsen, G.L.5    Irvin, C.G.6    Gelfand, E.W.7
  • 81
    • 0032957450 scopus 로고    scopus 로고
    • Role of ige in the development of allergic airway inflammation and airway hyperresponsiveness-a murine model
    • Hamelmann E, Tadeda K, Oshiba A, Gelfand EW. Role of IgE in the development of allergic airway inflammation and airway hyperresponsiveness-a murine model. Allergy 1999;54:297-305.
    • (1999) Allergy , vol.54 , pp. 297-305
    • Hamelmann, E.1    Tadeda, K.2    Oshiba, A.3    Gelfand, E.W.4
  • 87
    • 0032536837 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription factor 6 (STAT6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production
    • Kuperman D, Schofield B, Wills KM, Grusby MJ. Signal transducer and activator of transcription factor 6 (STAT6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. J Exp Med 1998;187:939-948.
    • (1998) J Exp Med , vol.187 , pp. 939-948
    • Kuperman, D.1    Schofield, B.2    Wills, K.M.3    Grusby, M.J.4
  • 88
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
    • Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Znang Y, Elias JA. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999;103: 779-788.
    • (1999) J Clin Invest , vol.103 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3    Chen, Q.4    Geba, G.P.5    Wang, J.6    Znang, Y.7    Elias, J.A.8


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