-
1
-
-
0028970060
-
Interleukin-12: A proinflammatory cytokine with immuno-regulatory functions that bridge innate resistance and antigen-specific adaptive immunity
-
Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immuno-regulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251.
-
(1995)
Annu. Rev. Immunol.
, vol.13
, pp. 251
-
-
Trinchieri, G.1
-
2
-
-
0029047009
-
Interleukin-12: Biologic activity, therapeutic utility, and role in disease
-
Hendrzak, J. A., and M. J. Brunda. 1995. Interleukin-12: biologic activity, therapeutic utility, and role in disease. Lab. Invest. 72:619.
-
(1995)
Lab. Invest.
, vol.72
, pp. 619
-
-
Hendrzak, J.A.1
Brunda, M.J.2
-
3
-
-
0029617459
-
IL-12 receptors and receptor antagonists
-
Presky, D. H., U. Gubler, R. A. Chizzonite, and M. K. Gately. 1995. IL-12 receptors and receptor antagonists. Res. Immunol. 146:439.
-
(1995)
Res. Immunol.
, vol.146
, pp. 439
-
-
Presky, D.H.1
Gubler, U.2
Chizzonite, R.A.3
Gately, M.K.4
-
4
-
-
0028235663
-
Expression cloning of a human IL-12 receptor component: A new member of the cytokine receptor superfamily with strong homology to gp130
-
Chua, A. O., R. Chizzonite, B. B. Desai, T. P. Truitt, P. Nunes, L. J. Minetti, R. R. Warrier, D. H. Presky, J. F. Levine, M. K. Gately, and U. Gubler. 1994. Expression cloning of a human IL-12 receptor component: a new member of the cytokine receptor superfamily with strong homology to gp130. J. Immunol. 153:128.
-
(1994)
J. Immunol.
, vol.153
, pp. 128
-
-
Chua, A.O.1
Chizzonite, R.2
Desai, B.B.3
Truitt, T.P.4
Nunes, P.5
Minetti, L.J.6
Warrier, R.R.7
Presky, D.H.8
Levine, J.F.9
Gately, M.K.10
Gubler, U.11
-
5
-
-
0028892869
-
Cloning and characterization of a mouse IL-12 receptor-β component
-
Chua, A. O., V. L. Wilkinson, D. H. Presky, and U. Gubler. 1995. Cloning and characterization of a mouse IL-12 receptor-β component. J. Immunol. 155:4286.
-
(1995)
J. Immunol.
, vol.155
, pp. 4286
-
-
Chua, A.O.1
Wilkinson, V.L.2
Presky, D.H.3
Gubler, U.4
-
6
-
-
0030445948
-
A functional interleukin-12 receptor complex is composed of two beta-type cytokine receptor subunits
-
Presky, D. H., H. Yang, L. J. Minetti, A. O. Chua, N. Nabavi, C. Y. Wu, M. K. Gately, and U. Gubler. 1996. A functional interleukin-12 receptor complex is composed of two beta-type cytokine receptor subunits. Proc. Natl. Acad. Sci. USA 93:14002.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14002
-
-
Presky, D.H.1
Yang, H.2
Minetti, L.J.3
Chua, A.O.4
Nabavi, N.5
Wu, C.Y.6
Gately, M.K.7
Gubler, U.8
-
7
-
-
1842387765
-
Biological function and distribution of human interleukin-12 receptor β chain
-
Wu, C.-Y., R. R. Warrier, D. M. Carvajal, A. O. Chua, L. J. Minetti, R. Chizzonite, P. K. A. Mongini, A. S. Stern, U. Gubler, D. H. Presky, and M. K. Gately. 1996. Biological function and distribution of human interleukin-12 receptor β chain. Eur. J. Immunol. 26:345.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 345
-
-
Wu, C.-Y.1
Warrier, R.R.2
Carvajal, D.M.3
Chua, A.O.4
Minetti, L.J.5
Chizzonite, R.6
Mongini, P.K.A.7
Stern, A.S.8
Gubler, U.9
Presky, D.H.10
Gately, M.K.11
-
8
-
-
0028096083
-
Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo
-
Gately, M. K., R. R. Warrier, S. Honasoge, D. M. Carvajal, D. A. Faherty, S. E. Connaughton, T. D. Anderson, U. Sarmiento, B. R. Hubbard, and M. Murphy. 1994. Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo. Int. Immunol. 6:157.
-
(1994)
Int. Immunol.
, vol.6
, pp. 157
-
-
Gately, M.K.1
Warrier, R.R.2
Honasoge, S.3
Carvajal, D.M.4
Faherty, D.A.5
Connaughton, S.E.6
Anderson, T.D.7
Sarmiento, U.8
Hubbard, B.R.9
Murphy, M.10
-
9
-
-
0004136246
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Sambrook, J., E. T. Fritsch, and T. Maniatis. 1989. Molecular Cloning, A Laboratory Manual, 2nd Ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(1989)
Molecular Cloning, a Laboratory Manual, 2nd Ed.
-
-
Sambrook, J.1
Fritsch, E.T.2
Maniatis, T.3
-
10
-
-
0026023289
-
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
-
Soriano, P., C. Montgomery, R. Geske, and A. Bradley. 1991. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64:693.
-
(1991)
Cell
, vol.64
, pp. 693
-
-
Soriano, P.1
Montgomery, C.2
Geske, R.3
Bradley, A.4
-
11
-
-
0028534657
-
Characterization of E-selectin deficient mice: Demonstration of overlapping function of the endothelial selectins
-
Labow, M. A., C. R. Norton, J. M. Rumberger, K. M. Lombard-Gillooly, D. J. Shuster, J. Hubbard, R. Bertko, P. A. Knaack, R. W. Terry, M. L. Harbison, F. Kontgen, C. L. Stewart, K. W. McIntyre, P. C. Will, D. K. Burns, and B. A. Wolitzky. 1994. Characterization of E-selectin deficient mice: demonstration of overlapping function of the endothelial selectins. Immunity 1:709.
-
(1994)
Immunity
, vol.1
, pp. 709
-
-
Labow, M.A.1
Norton, C.R.2
Rumberger, J.M.3
Lombard-Gillooly, K.M.4
Shuster, D.J.5
Hubbard, J.6
Bertko, R.7
Knaack, P.A.8
Terry, R.W.9
Harbison, M.L.10
Kontgen, F.11
Stewart, C.L.12
McIntyre, K.W.13
Will, P.C.14
Burns, D.K.15
Wolitzky, B.A.16
-
13
-
-
0025739379
-
Simplified mammalian DNA isolation procedure
-
Laird, P. W., A. Zijderveld, K. Linders, M. A. Rudnicki, R. Jaenish, and A. Berns. 1991. Simplified mammalian DNA isolation procedure. Nucleic Acids Res. 19:4293.
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 4293
-
-
Laird, P.W.1
Zijderveld, A.2
Linders, K.3
Rudnicki, M.A.4
Jaenish, R.5
Berns, A.6
-
15
-
-
16044363695
-
IL-12-deficient mice are defective in IFNγ production and type 1 cytokine responses
-
Magram, J., S. E. Connaughton, R. R. Warrier, D. M. Carvajal, C.-Y. Wu, J. Ferrante, C. Stewart, U. Sarmiento, D. A. Faherty, and M. K. Gately. 1996. IL-12-deficient mice are defective in IFNγ production and type 1 cytokine responses. Immunity 4:471.
-
(1996)
Immunity
, vol.4
, pp. 471
-
-
Magram, J.1
Connaughton, S.E.2
Warrier, R.R.3
Carvajal, D.M.4
Wu, C.-Y.5
Ferrante, J.6
Stewart, C.7
Sarmiento, U.8
Faherty, D.A.9
Gately, M.K.10
-
16
-
-
0026523212
-
IL-12 receptor. I. Characterization of the receptor on phytohemagglutinin-activated human lymphoblasts
-
Chizzonite, R., T. Truitt, B. B. Desai, P. Nunes, F. J. Podlaski, A. S. Stern, and M. K. Gately. 1992. IL-12 receptor. I. Characterization of the receptor on phytohemagglutinin-activated human lymphoblasts. J. Immunol. 148:3117.
-
(1992)
J. Immunol.
, vol.148
, pp. 3117
-
-
Chizzonite, R.1
Truitt, T.2
Desai, B.B.3
Nunes, P.4
Podlaski, F.J.5
Stern, A.S.6
Gately, M.K.7
-
17
-
-
0026588207
-
Cloning and expression of murine IL-12
-
Schoenhaut, D. S., A. O. Chua, A. G. Wolitzky, P. M. Quinn, C. M. Dwyer, W. McComas, P. C. Familletii, M. K. Gately, and U. Gubler. 1992. Cloning and expression of murine IL-12. J. Immunol. 148:3433.
-
(1992)
J. Immunol.
, vol.148
, pp. 3433
-
-
Schoenhaut, D.S.1
Chua, A.O.2
Wolitzky, A.G.3
Quinn, P.M.4
Dwyer, C.M.5
McComas, W.6
Familletii, P.C.7
Gately, M.K.8
Gubler, U.9
-
18
-
-
0025745472
-
IL-12: Monoclonal antibodies specific for the 40-kDa subunit block receptor binding and biologic activity on activated human lymphoblasts
-
Chizzonite, R., T. Truitt, F. J. Podlaski, A. G. Wolitzky, P. M. Quinn, P. Nunes, A. S. Stern, and M. K. Gately. 1991. IL-12: monoclonal antibodies specific for the 40-kDa subunit block receptor binding and biologic activity on activated human lymphoblasts. J. Immunol. 147:1548.
-
(1991)
J. Immunol.
, vol.147
, pp. 1548
-
-
Chizzonite, R.1
Truitt, T.2
Podlaski, F.J.3
Wolitzky, A.G.4
Quinn, P.M.5
Nunes, P.6
Stern, A.S.7
Gately, M.K.8
-
19
-
-
0022005744
-
Analysis of radioligand binding experiments: A collection of computer programs for the IBM PC
-
McPherson, G. A. 1985. Analysis of radioligand binding experiments: a collection of computer programs for the IBM PC. J. Pharmacol. Methods 14:213.
-
(1985)
J. Pharmacol. Methods
, vol.14
, pp. 213
-
-
McPherson, G.A.1
-
20
-
-
84969001783
-
The attractions of proteins for small molecules and ions
-
Scatchard, G. 1949. The attractions of proteins for small molecules and ions. Ann. NY Acad. Sci. 51:660.
-
(1949)
Ann. NY Acad. Sci.
, vol.51
, pp. 660
-
-
Scatchard, G.1
-
21
-
-
0028340969
-
Expression and methylation of imprinted genes during in vitro differentiation of mouse parthenogenetic and androgenetic embryonic stem cells
-
Szabo, P., and J. R. Mann. 1994. Expression and methylation of imprinted genes during in vitro differentiation of mouse parthenogenetic and androgenetic embryonic stem cells. Development 120:1651.
-
(1994)
Development
, vol.120
, pp. 1651
-
-
Szabo, P.1
Mann, J.R.2
-
23
-
-
0027491655
-
+ T cells to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming
-
+ T cells to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming. Proc. Natl. Acad. Sci. USA 90:10188.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10188
-
-
Seder, R.A.1
Gazzinelli, R.2
Sher, A.3
Paul, W.4
-
25
-
-
0028967287
-
Mouse interleukin-12 (IL-12) p40 homodimer: A potent IL-12 antagonist
-
Gillesen, S., D. Carvajal, P. Ling, F. J. Podlaski, D. L. Stremlo, P. C. Familletti, U. Gubler, D. H. Presky, A. S. Stern, and M. K. Gately. 1995. Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist. Eur. J. Immunol. 25:200.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 200
-
-
Gillesen, S.1
Carvajal, D.2
Ling, P.3
Podlaski, F.J.4
Stremlo, D.L.5
Familletti, P.C.6
Gubler, U.7
Presky, D.H.8
Stern, A.S.9
Gately, M.K.10
-
26
-
-
17544399131
-
Interleukin-12 antagonist activity of mouse interleukin-12 p40 homodimer in vitro and in vivo
-
Gately, M. K., D. M. Carvajal, S. E. Connaughton, S. Gillessen, R. R. Warrier, K. D. Kolinsky, V. L. Wilkinson, C. M. Dwyer, G. F. Higgins, Jr., F. J. Podlaski, D. A. Faherty, P. C. Familletti, A. S. Stern, and D. H. Presky. 1996. Interleukin-12 antagonist activity of mouse interleukin-12 p40 homodimer in vitro and in vivo. Ann. NY Acad. Sci. 795:1.
-
(1996)
Ann. NY Acad. Sci.
, vol.795
, pp. 1
-
-
Gately, M.K.1
Carvajal, D.M.2
Connaughton, S.E.3
Gillessen, S.4
Warrier, R.R.5
Kolinsky, K.D.6
Wilkinson, V.L.7
Dwyer, C.M.8
Higgins Jr., G.F.9
Podlaski, F.J.10
Faherty, D.A.11
Familletti, P.C.12
Stern, A.S.13
Presky, D.H.14
-
27
-
-
0030002111
-
Genetically resistent mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
-
Mattner, F., J. Magram, J. Ferrante, P. Launois, K. Di Padova, R. Behin, M. K. Gately, J. A. Louis, and G. Alber. 1996. Genetically resistent mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur. J. Immunol. 26:1553.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 1553
-
-
Mattner, F.1
Magram, J.2
Ferrante, J.3
Launois, P.4
Di Padova, K.5
Behin, R.6
Gately, M.K.7
Louis, J.A.8
Alber, G.9
-
28
-
-
0029937270
-
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
-
Kaplan, M. H., Y.-L. Sun, T. Hoey, and M. J. Grusby. 1996. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 382:174.
-
(1996)
Nature
, vol.382
, pp. 174
-
-
Kaplan, M.H.1
Sun, Y.-L.2
Hoey, T.3
Grusby, M.J.4
-
29
-
-
15844396183
-
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
-
Thierfelder, W. E., J. M. van Deursen, K. Yamamoto, R. A. Tripp, S. R. Sarawar, R. T. Carson, M. Y. Sangster, D. A. A. Vignali, P. C. Doherty, G. C. Grosveld, and J. N. Ihle. 1996. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 382:171.
-
(1996)
Nature
, vol.382
, pp. 171
-
-
Thierfelder, W.E.1
Van Deursen, J.M.2
Yamamoto, K.3
Tripp, R.A.4
Sarawar, S.R.5
Carson, R.T.6
Sangster, M.Y.7
Vignali, D.A.A.8
Doherty, P.C.9
Grosveld, G.C.10
Ihle, J.N.11
-
30
-
-
0028956699
-
Activated T cells induce interleukin-12 production by monocytes via CD40-CD40 ligand interaction
-
Shu, U., M. Kiniwa, C.-Y. Wu, C. Maliszewski, N. Vezzio, J. Hakimi, M. K. Gately and G. Delespesse. 1995. Activated T cells induce interleukin-12 production by monocytes via CD40-CD40 ligand interaction. Eur. J. Immunol. 25:1125.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 1125
-
-
Shu, U.1
Kiniwa, M.2
Wu, C.-Y.3
Maliszewski, C.4
Vezzio, N.5
Hakimi, J.6
Gately, M.K.7
Delespesse, G.8
-
31
-
-
0029965957
-
CD40 ligand is required for protective cell-mediated immunity to Leishmania major
-
Campbell, K. A., P. J. Ovendale, M. K. Kennedy, W. C. Fanslow, S. G. Reed, and C. R. Maliszewski. 1996. CD40 ligand is required for protective cell-mediated immunity to Leishmania major. Immunity 4:283.
-
(1996)
Immunity
, vol.4
, pp. 283
-
-
Campbell, K.A.1
Ovendale, P.J.2
Kennedy, M.K.3
Fanslow, W.C.4
Reed, S.G.5
Maliszewski, C.R.6
-
32
-
-
0029558557
-
The effects of IL-12 on B-cell subset function
-
Metzger, D. W., L. A. Vogel, V. H. Van Cleave, T. L. Lester, and J. M. Buchanan. 1995. The effects of IL-12 on B-cell subset function. Res. Immunol. 146:499.
-
(1995)
Res. Immunol.
, vol.146
, pp. 499
-
-
Metzger, D.W.1
Vogel, L.A.2
Van Cleave, V.H.3
Lester, T.L.4
Buchanan, J.M.5
-
33
-
-
0030063347
-
IL-12 expression in AIDS-related lymphoma B cell lines
-
Benjamin, D., V. Sharma, M. Kubin, J. L. Klein, A. Sartori, J. Holliday, and G. Trinchieri. 1996. IL-12 expression in AIDS-related lymphoma B cell lines. J. Immunol. 156:1626.
-
(1996)
J. Immunol.
, vol.156
, pp. 1626
-
-
Benjamin, D.1
Sharma, V.2
Kubin, M.3
Klein, J.L.4
Sartori, A.5
Holliday, J.6
Trinchieri, G.7
-
34
-
-
0030448764
-
Evidence for multiple sites of interaction between IL-12 and its receptor
-
Presky, D. H., L. J. Minetti, S. Gillessen, U. Gubler, R. Chizzonite, A. S. Stern, and M. K. Gately. 1996. Evidence for multiple sites of interaction between IL-12 and its receptor. Ann. NY Acad. Sci. 795:390.
-
(1996)
Ann. NY Acad. Sci.
, vol.795
, pp. 390
-
-
Presky, D.H.1
Minetti, L.J.2
Gillessen, S.3
Gubler, U.4
Chizzonite, R.5
Stern, A.S.6
Gately, M.K.7
-
35
-
-
0029838313
-
Reduced incidence and severity of collagen-induced arthritis in interleukin-12 deficient mice
-
McIntyre, K., D. Shuster, K. Gillooly, R. R. Warrier, S. Connaughton, L. Hall, L. Arp, M. K. Gately, and J. Magram. 1996. Reduced incidence and severity of collagen-induced arthritis in interleukin-12 deficient mice. Eur. J. Immunol. 26:2933.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 2933
-
-
McIntyre, K.1
Shuster, D.2
Gillooly, K.3
Warrier, R.R.4
Connaughton, S.5
Hall, L.6
Arp, L.7
Gately, M.K.8
Magram, J.9
-
36
-
-
0025216937
-
Lymphokine control of in vivo immunoglobulin isotype selection
-
Finkelman, F. D., J. Holmes, I. M. Katona, J. F. Urban, M. P. Beckmann, L. S. Park, K. A. Schooley, R. L. Coffman, T. R. Mosmann, and L. S. Paul. 1990. Lymphokine control of in vivo immunoglobulin isotype selection. Annu. Rev. Immunol. 8:303.
-
(1990)
Annu. Rev. Immunol.
, vol.8
, pp. 303
-
-
Finkelman, F.D.1
Holmes, J.2
Katona, I.M.3
Urban, J.F.4
Beckmann, M.P.5
Park, L.S.6
Schooley, K.A.7
Coffman, R.L.8
Mosmann, T.R.9
Paul, L.S.10
|