메뉴 건너뛰기




Volumn 159, Issue 10, 1997, Pages 5005-5013

SCID Mice Reconstituted with IL-4-Deficient Lymphocytes, but Not Immunocompetent Lymphocytes, Are Resistant to Cutaneous Leishmaniasis

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 4; INTERLEUKIN 5; NITRIC OXIDE SYNTHASE; PARASITE ANTIGEN; PROTOZOON ANTIBODY;

EID: 0031573080     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (33)

References (70)
  • 4
    • 0028906863 scopus 로고
    • Antimicrobial response of a T cell-deficient host to cytokine therapy: Effect of interferon-gamma in experimental visceral leishmaniasis in nude mice
    • Murray, H. W., J. Hariprashad, B. Aguero, T. Arakawa, and H. Yeganegi. 1995. Antimicrobial response of a T cell-deficient host to cytokine therapy: effect of interferon-gamma in experimental visceral leishmaniasis in nude mice. J. Infect. Dis. 171:1309.
    • (1995) J. Infect. Dis. , vol.171 , pp. 1309
    • Murray, H.W.1    Hariprashad, J.2    Aguero, B.3    Arakawa, T.4    Yeganegi, H.5
  • 6
    • 0029077326 scopus 로고
    • IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis
    • Scharton-Kersten, T., L. C. C. Afonso, M. Wysocka, G. Trinchieri, and P. Scott. 1995. IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis. J. Immunol. 154:5320.
    • (1995) J. Immunol. , vol.154 , pp. 5320
    • Scharton-Kersten, T.1    Afonso, L.C.C.2    Wysocka, M.3    Trinchieri, G.4    Scott, P.5
  • 7
    • 0025915524 scopus 로고
    • + subsets in experimental cutaneous leishmaniasis
    • + subsets in experimental cutaneous leishmaniasis. Res. Immunol. 42:32.
    • (1991) Res. Immunol. , vol.42 , pp. 32
    • Scott, P.1
  • 8
    • 0024412797 scopus 로고
    • Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/He mice to infection with Leishmania major
    • Belosevic, M., D. L. Finbloom, P. H. van der Meide, M. V. Slayter, and C. Nacy. 1989. Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/He mice to infection with Leishmania major. J. Immunol. 143:266.
    • (1989) J. Immunol. , vol.143 , pp. 266
    • Belosevic, M.1    Finbloom, D.L.2    Van Der Meide, P.H.3    Slayter, M.V.4    Nacy, C.5
  • 9
    • 0028957830 scopus 로고
    • Sex-determined susceptibility and differential IFN-γ and TNF-α mRNA expression in DBA/2 mice infected with Leishmania mexicana
    • Satoskar, A., and J. Alexander. 1995. Sex-determined susceptibility and differential IFN-γ and TNF-α mRNA expression in DBA/2 mice infected with Leishmania mexicana. Immunology 84:1.
    • (1995) Immunology , vol.84 , pp. 1
    • Satoskar, A.1    Alexander, J.2
  • 10
    • 0025300228 scopus 로고
    • Macrophage killing of Leishmania parasites in vivo is mediated by nitric oxide from L-arginine
    • Liew, F. Y., S. Millot, C. Parkinson, R. M. J. Palmer, and S. Moncada. 1990. Macrophage killing of Leishmania parasites in vivo is mediated by nitric oxide from L-arginine. J. Immunol. 144:4794.
    • (1990) J. Immunol. , vol.144 , pp. 4794
    • Liew, F.Y.1    Millot, S.2    Parkinson, C.3    Palmer, R.M.J.4    Moncada, S.5
  • 11
    • 0027293460 scopus 로고
    • Effect of in vivo inhibition of nitric oxide production in murine leishmaniasis
    • Evans, T., L. Thai, D. L. Granger, and J. B. Hibbs, Jr. 1993. Effect of in vivo inhibition of nitric oxide production in murine leishmaniasis. J. Immunol. 151: 907.
    • (1993) J. Immunol. , vol.151 , pp. 907
    • Evans, T.1    Thai, L.2    Granger, D.L.3    Hibbs Jr., J.B.4
  • 12
    • 0024540908 scopus 로고
    • Reciprocal expression of interferon-gamma or interleukin-4 during the resolution or progression of murine leishmaniasis: Evidence for expansion of distinct helper T cell subsets
    • Heinzel, F. P., M. D. Sadick, B. J. Holaday, R. L. Coffmann, and R. M. Locksley. 1989. Reciprocal expression of interferon-gamma or interleukin-4 during the resolution or progression of murine leishmaniasis: evidence for expansion of distinct helper T cell subsets. J. Exp. Med. 169:59.
    • (1989) J. Exp. Med. , vol.169 , pp. 59
    • Heinzel, F.P.1    Sadick, M.D.2    Holaday, B.J.3    Coffmann, R.L.4    Locksley, R.M.5
  • 14
    • 0027302364 scopus 로고
    • Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis
    • Afonso, L. C. C., and P. Scott. 1993. Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis. Infect. Immun. 61:2952.
    • (1993) Infect. Immun. , vol.61 , pp. 2952
    • Afonso, L.C.C.1    Scott, P.2
  • 15
    • 0026500979 scopus 로고
    • IL-4 induces a Th2 response in Leishmania major-infected mice
    • Chatelain, R., K. Varkila, and R. L. Coffman. 1992. IL-4 induces a Th2 response in Leishmania major-infected mice. J. Immunol. 148:1182.
    • (1992) J. Immunol. , vol.148 , pp. 1182
    • Chatelain, R.1    Varkila, K.2    Coffman, R.L.3
  • 16
    • 0025752328 scopus 로고
    • Differential production of Th1 and Th2-derived cytokines does not determine the genetically controlled or vaccine induced rate of cure in murine visceral leishmaniasis
    • Kaye, P. M., A. J. Curry, and J. M. Blackwell. 1991. Differential production of Th1 and Th2-derived cytokines does not determine the genetically controlled or vaccine induced rate of cure in murine visceral leishmaniasis. J. Immunol. 146: 2763.
    • (1991) J. Immunol. , vol.146 , pp. 2763
    • Kaye, P.M.1    Curry, A.J.2    Blackwell, J.M.3
  • 18
    • 0027240219 scopus 로고
    • Interleukin 10(IL-10) inhibits human lymphocyte interferon-γ production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells
    • D'Andrea A., M. Aste-Amezaga, N. M. Valiante, X. Ma, M. Kubin, and G. Trinchieri. 1993. Interleukin 10(IL-10) inhibits human lymphocyte interferon-γ production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J. Exp. Med. 178:1041.
    • (1993) J. Exp. Med. , vol.178 , pp. 1041
    • D'Andrea, A.1    Aste-Amezaga, M.2    Valiante, N.M.3    Ma, X.4    Kubin, M.5    Trinchieri, G.6
  • 19
    • 0026648380 scopus 로고
    • Differential regulation of T helper phenotype development by interleukin 4 and 10 in an alpha beta T cell-receptor transgenic system
    • Hsieh, C. S., A. B. Heimberger, J. S. Gold, A. O'Gara, and K. M. Murphy. 1992. Differential regulation of T helper phenotype development by interleukin 4 and 10 in an alpha beta T cell-receptor transgenic system. Proc. Natl. Acad. Sci. USA 89:6065.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6065
    • Hsieh, C.S.1    Heimberger, A.B.2    Gold, J.S.3    O'Gara, A.4    Murphy, K.M.5
  • 23
    • 0027464843 scopus 로고
    • Human peripheral blood basophils primed by interleukin 3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulation
    • Brunner, T., C. H. Heusser, and C. A. Dahinden. 1993. Human peripheral blood basophils primed by interleukin 3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulation. J. Exp. Med. 177:605.
    • (1993) J. Exp. Med. , vol.177 , pp. 605
    • Brunner, T.1    Heusser, C.H.2    Dahinden, C.A.3
  • 24
    • 0028787484 scopus 로고
    • Disruption of the murine interleukin-4 gene inhibits disease progression during Leishmania mexicana infection but does not increase control of Leishmania donovani infection
    • Satoskar, A., H. Bluethmann, and J. Alexander. 1995. Disruption of the murine interleukin-4 gene inhibits disease progression during Leishmania mexicana infection but does not increase control of Leishmania donovani infection. Infect. Immun. 63:4894.
    • (1995) Infect. Immun. , vol.63 , pp. 4894
    • Satoskar, A.1    Bluethmann, H.2    Alexander, J.3
  • 25
    • 0030023112 scopus 로고    scopus 로고
    • Susceptibility to Leishmania major in interleukin-4-deficient mice
    • Noben Trauth, N., P. Kopf, and I. Muller. 1996. Susceptibility to Leishmania major in interleukin-4-deficient mice. Science 271:987.
    • (1996) Science , vol.271 , pp. 987
    • Noben Trauth, N.1    Kopf, P.2    Muller, I.3
  • 26
    • 0019518610 scopus 로고
    • A quick, simple method for purifying Leishmania mexicana amastigotes in large numbers
    • Hart, D. T., K. Vickerman, and G. H. Coombs. 1981. A quick, simple method for purifying Leishmania mexicana amastigotes in large numbers. Parasitology 82: 345.
    • (1981) Parasitology , vol.82 , pp. 345
    • Hart, D.T.1    Vickerman, K.2    Coombs, G.H.3
  • 27
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248.
    • (1976) Anal. Biochem. , vol.72 , pp. 248
    • Bradford, M.M.1
  • 28
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
    • Chomszynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156.
    • (1987) Anal. Biochem. , vol.162 , pp. 156
    • Chomszynski, P.1    Sacchi, N.2
  • 29
    • 0026786405 scopus 로고
    • Standardization of mRNA titration using a polymerase chain reaction method involving co-amplification with a multispecific internal control
    • Bouaboula, M., P. Legoux, B. Pessegue, B. Delpech, X. Dumont, M. Piechaczyk, P. Casellas, and D. Shire. 1992. Standardization of mRNA titration using a polymerase chain reaction method involving co-amplification with a multispecific internal control. J. Biol. Chem. 267:21830.
    • (1992) J. Biol. Chem. , vol.267 , pp. 21830
    • Bouaboula, M.1    Legoux, P.2    Pessegue, B.3    Delpech, B.4    Dumont, X.5    Piechaczyk, M.6    Casellas, P.7    Shire, D.8
  • 30
    • 0025355882 scopus 로고
    • Analysis of cytokine mRNA and DNA: Detection and quantitation by competitive polymerase chain reaction
    • Gilliland, G. S., S. Perrin, K. Blanchard, and H. F. Bunn. 1990. Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction. Proc. Natl. Acad. Sci. USA 87:2725.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 2725
    • Gilliland, G.S.1    Perrin, S.2    Blanchard, K.3    Bunn, H.F.4
  • 31
    • 0000841337 scopus 로고
    • Open exchange of reagents and information useful for the measurement of cytokine mRNA levels by PCR
    • Shire, D. 1993. Open exchange of reagents and information useful for the measurement of cytokine mRNA levels by PCR. Eur. Cytokine Netw. 4:161.
    • (1993) Eur. Cytokine Netw. , vol.4 , pp. 161
    • Shire, D.1
  • 33
    • 0027184018 scopus 로고
    • The role of natural killer cells in innate resistance to infection
    • Bancroft, G. J. 1993. The role of natural killer cells in innate resistance to infection. Curr. Opin. Immunol. 5:503.
    • (1993) Curr. Opin. Immunol. , vol.5 , pp. 503
    • Bancroft, G.J.1
  • 34
    • 0027472336 scopus 로고
    • Interleukin-4 transgenic mice of resistant background are susceptible to Leishmania major
    • Leal, L. M., D. W. Moss, R. Kuhn, W. Muller, and F. Y. Liew. 1993. Interleukin-4 transgenic mice of resistant background are susceptible to Leishmania major. Eur. J. Immunol. 23:566.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 566
    • Leal, L.M.1    Moss, D.W.2    Kuhn, R.3    Muller, W.4    Liew, F.Y.5
  • 35
    • 0030021084 scopus 로고    scopus 로고
    • Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice
    • Carrera, L., R. T. Gazzinelli, R. Badolato, S. Hieny, W. Muller, R. Kuhn, and D. L. Sacks. 1996. Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice. J. Exp. Med. 183:515.
    • (1996) J. Exp. Med. , vol.183 , pp. 515
    • Carrera, L.1    Gazzinelli, R.T.2    Badolato, R.3    Hieny, S.4    Muller, W.5    Kuhn, R.6    Sacks, D.L.7
  • 39
    • 0028089711 scopus 로고
    • Deficient expression of co-stimulatory molecules on Leishmania-infected macrophages
    • Kaye, P. M., N. J. Rogers, A. J. Curry, and J. C. Scott. 1994. Deficient expression of co-stimulatory molecules on Leishmania-infected macrophages. Eur. J. Immunol. 24:2850.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2850
    • Kaye, P.M.1    Rogers, N.J.2    Curry, A.J.3    Scott, J.C.4
  • 40
  • 41
    • 0027930810 scopus 로고
    • The immune response to Plasmodium chabaudi malaria in interleukin-4-deficient mice
    • Von-der-Weid, T., M. Kopf, G. Kohler, and J. Langhorne. 1994. The immune response to Plasmodium chabaudi malaria in interleukin-4-deficient mice. Eur. J. Immunol. 224:2285.
    • (1994) Eur. J. Immunol. , vol.224 , pp. 2285
    • Von-der-Weid, T.1    Kopf, M.2    Kohler, G.3    Langhorne, J.4
  • 42
    • 0029796717 scopus 로고    scopus 로고
    • In IL-4 deficient mice, alum not only generates Th1 responses equivalent to Freund's complete adjuvant, but also continues to induce Th2-type cytokine production
    • Brewer, J., M. Connacher, A. Satoskar, H. Bluethmann, and J. Alexander. 1996. In IL-4 deficient mice, alum not only generates Th1 responses equivalent to Freund's complete adjuvant, but also continues to induce Th2-type cytokine production. Eur. J. Immunol. 26:2062.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2062
    • Brewer, J.1    Connacher, M.2    Satoskar, A.3    Bluethmann, H.4    Alexander, J.5
  • 43
    • 0026042191 scopus 로고
    • A possible novel pathway of regulation by murine T helper type-2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages
    • Liew, F. Y., Y. Li, A. Severn, S. Millot, J. Schimdt, M. Salter, and S. Moncada. 1991. A possible novel pathway of regulation by murine T helper type-2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages. Eur. J. Immunol. 21:2489.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2489
    • Liew, F.Y.1    Li, Y.2    Severn, A.3    Millot, S.4    Schimdt, J.5    Salter, M.6    Moncada, S.7
  • 44
    • 0024352297 scopus 로고
    • Macrophage activation by interferon-gamma from host-protective T cells is inhibited by interleukin (IL)-3 and IL-4 produced by disease promoting T cells in leishmaniasis
    • Liew, F. Y., S. Millott, Y. Li, R. Lelchuk, W. L. Chan, and H. Ziltenger. 1989. Macrophage activation by interferon-gamma from host-protective T cells is inhibited by interleukin (IL)-3 and IL-4 produced by disease promoting T cells in leishmaniasis. Eur. J. Immunol. 19:1227.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 1227
    • Liew, F.Y.1    Millott, S.2    Li, Y.3    Lelchuk, R.4    Chan, W.L.5    Ziltenger, H.6
  • 46
    • 0027422313 scopus 로고
    • + T cells from alpha beta TCR transgenic mice: IL-12 substitution from macrophages to stimulate IFN-gamma production is IFN-gamma-dependent
    • + T cells from alpha beta TCR transgenic mice: IL-12 substitution from macrophages to stimulate IFN-gamma production is IFN-gamma-dependent. Int. Immunol. 5:1119.
    • (1993) Int. Immunol. , vol.5 , pp. 1119
    • Macatonia, S.E.1    Hsieh, C.S.2    Murphy, K.M.3    O'Garra, A.4
  • 48
    • 0027473217 scopus 로고
    • Parasitism of epidermal Langerhans cells in experimental cutaneous leishmaniasis with Leishmania major
    • Blank, C., H. Fuchs, K. Rappersberger, M. Rollinghoff, and H. Moll. 1993. Parasitism of epidermal Langerhans cells in experimental cutaneous leishmaniasis with Leishmania major. J. Infect. Dis. 167:418.
    • (1993) J. Infect. Dis. , vol.167 , pp. 418
    • Blank, C.1    Fuchs, H.2    Rappersberger, K.3    Rollinghoff, M.4    Moll, H.5
  • 49
    • 0027260963 scopus 로고
    • Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni
    • Wynn, T. A., I. Eltoum, A. W. Cheever, F. A. Lewis, W. C. Gause, and A. Sher. 1993. Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. J. Immunol. 151:1430.
    • (1993) J. Immunol. , vol.151 , pp. 1430
    • Wynn, T.A.1    Eltoum, I.2    Cheever, A.W.3    Lewis, F.A.4    Gause, W.C.5    Sher, A.6
  • 50
    • 0027195839 scopus 로고
    • Lymphokine regulation of granuloma formation in murine schistosomiasis mansoni
    • Lukacs, N. W., and D. L. Boros. 1993. Lymphokine regulation of granuloma formation in murine schistosomiasis mansoni. Clin. Immunol. Immunopathol. 68: 57.
    • (1993) Clin. Immunol. Immunopathol. , vol.68 , pp. 57
    • Lukacs, N.W.1    Boros, D.L.2
  • 52
    • 0028807612 scopus 로고
    • + cells at the site of antigen deposition predicts the development of a T helper 2 cell response to Schistosoma mansoni eggs
    • + cells at the site of antigen deposition predicts the development of a T helper 2 cell response to Schistosoma mansoni eggs. J. Immunol. 155:4844.
    • (1995) J. Immunol. , vol.155 , pp. 4844
    • Sabin, E.A.1    Pearce, E.J.2
  • 53
    • 0026570426 scopus 로고
    • Cytokine control of Leishmania infection in the BALB/c mouse: Enhancement and inhibition of parasite growth by local administration of IL-2 or IL-4 is species and time dependent
    • Lezama-Davila, C. M., D. M. Williams, G. Gallagher, and J. Alexander. 1992. Cytokine control of Leishmania infection in the BALB/c mouse: enhancement and inhibition of parasite growth by local administration of IL-2 or IL-4 is species and time dependent. Parasite Immunol. 14:37.
    • (1992) Parasite Immunol. , vol.14 , pp. 37
    • Lezama-Davila, C.M.1    Williams, D.M.2    Gallagher, G.3    Alexander, J.4
  • 55
    • 0027500332 scopus 로고
    • Reconstitution of C.B-17 scid mice with BALB/c T cells initiates a T helper type-1 response and renders them capable of healing Leishmania major infection
    • Varkila, K., R. Chatelaine, L. M. C. C. Leal, and R. L. Coffman. 1993. Reconstitution of C.B-17 scid mice with BALB/c T cells initiates a T helper type-1 response and renders them capable of healing Leishmania major infection. Eur. J. Immunol. 23:262.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 262
    • Varkila, K.1    Chatelaine, R.2    Leal, L.M.C.C.3    Coffman, R.L.4
  • 56
    • 0028129526 scopus 로고
    • Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major
    • Stenger, S., H. Thuring, M. Rollinghoff, and C. Bogdan. 1994. Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major. J. Exp. Med. 180:783.
    • (1994) J. Exp. Med. , vol.180 , pp. 783
    • Stenger, S.1    Thuring, H.2    Rollinghoff, M.3    Bogdan, C.4
  • 58
    • 0027395378 scopus 로고
    • Persistence of virulent Leishmania major in murine cutaneous leishmaniasis: A possible hazard for the host
    • Aebischer, T., S. F. Moody, and E. Handman. 1993. Persistence of virulent Leishmania major in murine cutaneous leishmaniasis: a possible hazard for the host. Infect. Immun. 61:220.
    • (1993) Infect. Immun. , vol.61 , pp. 220
    • Aebischer, T.1    Moody, S.F.2    Handman, E.3
  • 59
    • 0026514391 scopus 로고
    • HIV-Leishmania co-infections in Italy: Isoenzyme characterization of Leishmania causing visceral leishmaniasis in HIV patients
    • Gramiccia, M., L. Gradoni, and M. Troiani. 1992. HIV-Leishmania co-infections in Italy: isoenzyme characterization of Leishmania causing visceral leishmaniasis in HIV patients. Trans. R. Soc. Trop. Med. Hyg. 86:161.
    • (1992) Trans. R. Soc. Trop. Med. Hyg. , vol.86 , pp. 161
    • Gramiccia, M.1    Gradoni, L.2    Troiani, M.3
  • 60
    • 0026094299 scopus 로고
    • T cell memory is short-lived in the absence of antigen
    • Gray, D., and P. Matzinger. 1991. T cell memory is short-lived in the absence of antigen. J. Exp. Med. 174:969.
    • (1991) J. Exp. Med. , vol.174 , pp. 969
    • Gray, D.1    Matzinger, P.2
  • 61
    • 0029882271 scopus 로고    scopus 로고
    • Constitutive production of IL-4 and IL-10 and stimulated production of IL-8 by normal peripheral blood eosinophils
    • Nakajima, H., G. J. Gleich, and H. Kita. 1996. Constitutive production of IL-4 and IL-10 and stimulated production of IL-8 by normal peripheral blood eosinophils. J. Immunol. 156:4859.
    • (1996) J. Immunol. , vol.156 , pp. 4859
    • Nakajima, H.1    Gleich, G.J.2    Kita, H.3
  • 63
    • 0028211512 scopus 로고
    • Mast cells augment lesion size and persistence during experimental Leishmania major infection in mouse
    • Wershil, B. K., C. M. Theodas, S. J. Galli, and R. G. Titus. 1994. Mast cells augment lesion size and persistence during experimental Leishmania major infection in mouse. J. Immunol. 152:4563.
    • (1994) J. Immunol. , vol.152 , pp. 4563
    • Wershil, B.K.1    Theodas, C.M.2    Galli, S.J.3    Titus, R.G.4
  • 64
    • 0025133974 scopus 로고
    • Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody: Evidence for a T cell-dependent, interferon gamma-independent mechanism
    • Sadick, M. D., F. P. Heinzel, B. J. Holaday, R. T. Pu, R. S. Dawkins, and R. M. Locksley. 1990. Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody: evidence for a T cell-dependent, interferon gamma-independent mechanism. J. Exp. Med. 171:115.
    • (1990) J. Exp. Med. , vol.171 , pp. 115
    • Sadick, M.D.1    Heinzel, F.P.2    Holaday, B.J.3    Pu, R.T.4    Dawkins, R.S.5    Locksley, R.M.6
  • 66
    • 0026056142 scopus 로고
    • IFN-gamma modulates the early development of Th1 and Th2 responses in murine model of cutaneous leishmaniasis
    • Scott, P. 1991. IFN-gamma modulates the early development of Th1 and Th2 responses in murine model of cutaneous leishmaniasis. J. Immunol. 147:3149.
    • (1991) J. Immunol. , vol.147 , pp. 3149
    • Scott, P.1
  • 67
    • 0028906593 scopus 로고
    • T cell genetic background determines default T helper phenotype development in vitro
    • Hsieh, C. S., S. E. Macatonia, A. O'Garra, and K. M. Murphy. 1995. T cell genetic background determines default T helper phenotype development in vitro. J. Exp. Med. 181:713.
    • (1995) J. Exp. Med. , vol.181 , pp. 713
    • Hsieh, C.S.1    Macatonia, S.E.2    O'Garra, A.3    Murphy, K.M.4
  • 68
    • 0028939675 scopus 로고
    • T cell and non-T cell compartments can independently determine resistance to Leishmania major
    • Shankar, A. H., and R. G. Titus. 1995. T cell and non-T cell compartments can independently determine resistance to Leishmania major. J. Exp. Med. 181:845.
    • (1995) J. Exp. Med. , vol.181 , pp. 845
    • Shankar, A.H.1    Titus, R.G.2
  • 69
    • 0038223216 scopus 로고
    • The immunological significance of genetically determined cross reactivity between taxonomically distinct Leishmania species
    • IMEEE. Montpellier
    • Alexander, J., and J. M. Blackwell. 1986. The immunological significance of genetically determined cross reactivity between taxonomically distinct Leishmania species. In Leishmania: Taxonomie et Phylogenese. IMEEE. Montpellier, pp. 185-191.
    • (1986) Leishmania: Taxonomie et Phylogenese , pp. 185-191
    • Alexander, J.1    Blackwell, J.M.2
  • 70
    • 0024495092 scopus 로고
    • Influence of Lsh, H-2, and an H-11-linked gene on visceralization and metastasis associated with Leishmania mexicana infection in mice
    • Roberts, M. B., J. Alexander, and J. M. Blackwell. 1989. Influence of Lsh, H-2, and an H-11-linked gene on visceralization and metastasis associated with Leishmania mexicana infection in mice. Infect. Immun. 57:875.
    • (1989) Infect. Immun. , vol.57 , pp. 875
    • Roberts, M.B.1    Alexander, J.2    Blackwell, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.