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Volumn 58, Issue 7, 1999, Pages 1089-1095

Mechanism of p53-induced apoptosis

Author keywords

Apoptosis; Cancer; Cell cycle; Oncogene; p53; Transcription

Indexed keywords

PROTEIN P53;

EID: 0033201437     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00153-7     Document Type: Note
Times cited : (58)

References (80)
  • 3
    • 0025711796 scopus 로고
    • Cancer. A deadly inheritance
    • Vogelstein B, Cancer. A deadly inheritance. Nature 348: 681-682, 1990.
    • (1990) Nature , vol.348 , pp. 681-682
    • Vogelstein, B.1
  • 4
    • 0027109075 scopus 로고
    • P53, guardian of the genome
    • Lane DP, P53, guardian of the genome. Nature 358: 15-16, 1992.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 5
    • 0032568037 scopus 로고    scopus 로고
    • Small contribution of G1 checkpoint control manipulation to modulation of p53-mediated apoptosis
    • Canman CE and Kastan MB, Small contribution of G1 checkpoint control manipulation to modulation of p53-mediated apoptosis. Oncogene 16: 957-966, 1998.
    • (1998) Oncogene , vol.16 , pp. 957-966
    • Canman, C.E.1    Kastan, M.B.2
  • 7
    • 0032570820 scopus 로고    scopus 로고
    • Tumor necrosis factor-induced apoptosis stimulates p53 accumulation and p21WAF1 proteolysis in ME-180 cells
    • Donato NJ and Perez M, Tumor necrosis factor-induced apoptosis stimulates p53 accumulation and p21WAF1 proteolysis in ME-180 cells. J Biol Chem 273: 5067-5072, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 5067-5072
    • Donato, N.J.1    Perez, M.2
  • 10
    • 0030893175 scopus 로고    scopus 로고
    • Upregulation of endogenous p53 and induction of in vivo apoptosis in B-lineage lymphomas of Eμ-myc transgenic mice by deregulated C-myc transgene
    • Prasad VS, LaFond RE, Zhou M, Jacobsen KA, Osmond DG and Sidman CL, Upregulation of endogenous p53 and induction of in vivo apoptosis in B-lineage lymphomas of Eμ-myc transgenic mice by deregulated C-myc transgene. Mol Carcinog 18: 66-77, 1997.
    • (1997) Mol Carcinog , vol.18 , pp. 66-77
    • Prasad, V.S.1    LaFond, R.E.2    Zhou, M.3    Jacobsen, K.A.4    Osmond, D.G.5    Sidman, C.L.6
  • 11
    • 0030791513 scopus 로고    scopus 로고
    • Regulation of Myc-dependent apoptosis by p53, c-Jun N-terminal kinases/stress-activated protein kinases, and Mdm-2
    • Yu K, Ravera CP, Chen Y-NP and McMahon G, Regulation of Myc-dependent apoptosis by p53, c-Jun N-terminal kinases/stress-activated protein kinases, and Mdm-2. Cell Growth Differ 8: 731-742, 1997.
    • (1997) Cell Growth Differ , vol.8 , pp. 731-742
    • Yu, K.1    Ravera, C.P.2    Chen, Y.-N.P.3    McMahon, G.4
  • 12
    • 0031992159 scopus 로고    scopus 로고
    • E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2
    • Kowalik TF, DeGregori J, Leone G, Jakoi L and Nevins JR, E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ 9: 113-118, 1998.
    • (1998) Cell Growth Differ , vol.9 , pp. 113-118
    • Kowalik, T.F.1    DeGregori, J.2    Leone, G.3    Jakoi, L.4    Nevins, J.R.5
  • 13
    • 0030739355 scopus 로고    scopus 로고
    • Induction of DNA synthesis and apoptosis are separable functions of E2F-1
    • Phillips AC, BateS S, Ryan KM, Helin K and Vousden KH, Induction of DNA synthesis and apoptosis are separable functions of E2F-1. Genes Dev 11: 1853-1863, 1997.
    • (1997) Genes Dev , vol.11 , pp. 1853-1863
    • Phillips, A.C.1    Bates, S.2    Ryan, K.M.3    Helin, K.4    Vousden, K.H.5
  • 14
    • 0030850752 scopus 로고    scopus 로고
    • E2F1-induced apoptosis requires DNA binding but not trans-activation and is inhibited by the retinoblastoma protein through direct interaction
    • Hsieh J-K, Fredersdorf S, Kouzarides T, Martin K and Lu X, E2F1-induced apoptosis requires DNA binding but not trans-activation and is inhibited by the retinoblastoma protein through direct interaction. Genes Dev 11: 1840-1852, 1997.
    • (1997) Genes Dev , vol.11 , pp. 1840-1852
    • Hsieh, J.-K.1    Fredersdorf, S.2    Kouzarides, T.3    Martin, K.4    Lu, X.5
  • 15
    • 0030813584 scopus 로고    scopus 로고
    • Adenovirus-mediated overexpression of the transcription factor E2F-1 induces apoptosis in human breast and ovarian carcinoma cell lines and does not require p53
    • Hunt KK, Deng J, Liu T-J, Wilson-Heiner M, Swisher SG, Clayman G and Hung M-C, Adenovirus-mediated overexpression of the transcription factor E2F-1 induces apoptosis in human breast and ovarian carcinoma cell lines and does not require p53. Cancer Res 57: 4722-4726, 1997.
    • (1997) Cancer Res , vol.57 , pp. 4722-4726
    • Hunt, K.K.1    Deng, J.2    Liu, T.-J.3    Wilson-Heiner, M.4    Swisher, S.G.5    Clayman, G.6    Hung, M.-C.7
  • 16
    • 0030945245 scopus 로고    scopus 로고
    • P300 binding by E1A cosegregates with p53 induction but is dispensable for apoptosis
    • Chiou SK and White E, P300 binding by E1A cosegregates with p53 induction but is dispensable for apoptosis. J Virol 71: 3515-3525, 1997.
    • (1997) J Virol , vol.71 , pp. 3515-3525
    • Chiou, S.K.1    White, E.2
  • 19
    • 0028292480 scopus 로고
    • Identification of a p53-dependent negative response element in the bcl-2 gene
    • Miyashita T, Harigai M, Hanada M and Reed JC, Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res 54: 3131-3135, 1994.
    • (1994) Cancer Res , vol.54 , pp. 3131-3135
    • Miyashita, T.1    Harigai, M.2    Hanada, M.3    Reed, J.C.4
  • 21
    • 0030972216 scopus 로고    scopus 로고
    • Insulin like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-β1 on programmed cell death through a p53- and IGF-independent mechanism
    • Rajah R, Valentinis B and Cohen P, Insulin like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-β1 on programmed cell death through a p53- and IGF-independent mechanism. J Biol Chem 272: 12181-12188, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 12181-12188
    • Rajah, R.1    Valentinis, B.2    Cohen, P.3
  • 22
    • 0029742781 scopus 로고    scopus 로고
    • Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function
    • Ludwig RL, Bates S and Vousden KH, Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function. Mol Cell Biol 16: 4952-4960, 1996.
    • (1996) Mol Cell Biol , vol.16 , pp. 4952-4960
    • Ludwig, R.L.1    Bates, S.2    Vousden, K.H.3
  • 23
    • 0031806708 scopus 로고    scopus 로고
    • Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest
    • Ryan KM and Vousden KH, Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest. Mol Cell Biol 18: 3692-3698, 1998.
    • (1998) Mol Cell Biol , vol.18 , pp. 3692-3698
    • Ryan, K.M.1    Vousden, K.H.2
  • 24
    • 0032523940 scopus 로고    scopus 로고
    • Germ-line-derived hinge domain p53 mutants have lost apoptotic but not cell cycle arrest functions
    • Aurelio ON, Cajot J-F, Hua ML-H, Khwaja Z and Stanbridge EJ, Germ-line-derived hinge domain p53 mutants have lost apoptotic but not cell cycle arrest functions. Cancer Res 58: 2190-2195, 1998.
    • (1998) Cancer Res , vol.58 , pp. 2190-2195
    • Aurelio, O.N.1    Cajot, J.-F.2    Hua, M.L.-H.3    Khwaja, Z.4    Stanbridge, E.J.5
  • 28
    • 0030753187 scopus 로고    scopus 로고
    • Roles of p300, pocket proteins, and hTBP in E1A-mediated transcriptional regulation and inhibition of p53 transactivation activity
    • Sang NL, Avantaggiati ML and Giordano A, Roles of p300, pocket proteins, and hTBP in E1A-mediated transcriptional regulation and inhibition of p53 transactivation activity. J Cell Biochem 66: 277-285, 1997.
    • (1997) J Cell Biochem , vol.66 , pp. 277-285
    • Sang, N.L.1    Avantaggiati, M.L.2    Giordano, A.3
  • 29
    • 0032575079 scopus 로고    scopus 로고
    • Functional interplay between p53 and E2F through co-activator p300
    • Lee CW, Sorensen TS, Shikama N and LaThangue NB, Functional interplay between p53 and E2F through co-activator p300. Oncogene 16: 2695-2710, 1998.
    • (1998) Oncogene , vol.16 , pp. 2695-2710
    • Lee, C.W.1    Sorensen, T.S.2    Shikama, N.3    LaThangue, N.B.4
  • 30
    • 0032127947 scopus 로고    scopus 로고
    • Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function
    • Thomas A and White E, Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function. Genes Dev 12: 1975-1985, 1998.
    • (1998) Genes Dev , vol.12 , pp. 1975-1985
    • Thomas, A.1    White, E.2
  • 31
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt Y, Maya R, Kazaz A and Oren M, Mdm2 promotes the rapid degradation of p53. Nature 387: 296-299, 1997.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 32
    • 0030955170 scopus 로고    scopus 로고
    • Proteolytic cleavage of the mdm2 oncoprotein during apoptosis
    • Chen L, Marechal V, Moreau J, Levine AJ and Chen J, Proteolytic cleavage of the mdm2 oncoprotein during apoptosis. J Biol Chem 272: 22966-22973, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 22966-22973
    • Chen, L.1    Marechal, V.2    Moreau, J.3    Levine, A.J.4    Chen, J.5
  • 33
    • 0032127463 scopus 로고    scopus 로고
    • P53 facilitates pRb cleavage in IL-3-deprived cells: Novel pro-apoptotic activity of p53
    • Gottlieb E and Oren M, P53 facilitates pRb cleavage in IL-3-deprived cells: Novel pro-apoptotic activity of p53. EMBO J 17: 3587-3596, 1998.
    • (1998) EMBO J , vol.17 , pp. 3587-3596
    • Gottlieb, E.1    Oren, M.2
  • 34
    • 0032522453 scopus 로고    scopus 로고
    • Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct Jak kinase signaling pathways
    • Quelle FW, Wang JL, Feng J, Wang D, Cleveland JL, Ihle JN and Zambetti GP, Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct Jak kinase signaling pathways. Genes Dev 12: 1099-1107, 1998.
    • (1998) Genes Dev , vol.12 , pp. 1099-1107
    • Quelle, F.W.1    Wang, J.L.2    Feng, J.3    Wang, D.4    Cleveland, J.L.5    Ihle, J.N.6    Zambetti, G.P.7
  • 35
    • 0032474904 scopus 로고    scopus 로고
    • 1 protects cells from apoptosis induced by UV-irradiation or RNA polymerase II blockage
    • 1 protects cells from apoptosis induced by UV-irradiation or RNA polymerase II blockage. Oncogene 16: 3461-3469, 1998.
    • (1998) Oncogene , vol.16 , pp. 3461-3469
    • Bissonnette, N.1    Hunting, D.J.2
  • 36
    • 0030802364 scopus 로고    scopus 로고
    • A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis
    • Israeli D, Tessler E, Haupt Y, Elkeles A, Wilder S, Amson R, Telerman A and Oren M, A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis. EMBO J 16: 4384-4392, 1997.
    • (1997) EMBO J , vol.16 , pp. 4384-4392
    • Israeli, D.1    Tessler, E.2    Haupt, Y.3    Elkeles, A.4    Wilder, S.5    Amson, R.6    Telerman, A.7    Oren, M.8
  • 37
    • 0032522463 scopus 로고    scopus 로고
    • p53-dependent and -independent regulation of the death receptor KILLER/ DR5 gene expression in response to genotoxic stress and tumor necrosis factor α
    • Sheikh MS, Burns TF, Huang Y, Wu GS, AmundSon S, BrookS KS, Fornace AJ Jr and El-Deiry WS, p53-dependent and -independent regulation of the death receptor KILLER/ DR5 gene expression in response to genotoxic stress and tumor necrosis factor α. Cancer Res 58: 1593-1598, 1998.
    • (1998) Cancer Res , vol.58 , pp. 1593-1598
    • Sheikh, M.S.1    Burns, T.F.2    Huang, Y.3    Wu, G.S.4    Amundson, S.5    Brooks, K.S.6    Fornace A.J., Jr.7    El-Deiry, W.S.8
  • 38
    • 0032580334 scopus 로고    scopus 로고
    • Potential role for cathepsin D in p53-dependent tumor suppression and chemo-sensitivity
    • Wu GS, Saftig P, Peters C and El-Deiry WS, Potential role for cathepsin D in p53-dependent tumor suppression and chemo-sensitivity. Oncogene 16: 2177-2183, 1998.
    • (1998) Oncogene , vol.16 , pp. 2177-2183
    • Wu, G.S.1    Saftig, P.2    Peters, C.3    El-Deiry, W.S.4
  • 41
    • 0029585933 scopus 로고
    • Transcriptional activation plays a role in the induction of apoptosis by transiently transfected wild-type p53
    • Yonish-Rouach E, Deguin V, Zaitchouk T, Breugnot C, Mishal Z, Jenkins J and May E, Transcriptional activation plays a role in the induction of apoptosis by transiently transfected wild-type p53. Oncogene 11: 2197-2205, 1995.
    • (1995) Oncogene , vol.11 , pp. 2197-2205
    • Yonish-Rouach, E.1    Deguin, V.2    Zaitchouk, T.3    Breugnot, C.4    Mishal, Z.5    Jenkins, J.6    May, E.7
  • 42
    • 0030013337 scopus 로고    scopus 로고
    • Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis
    • Donatella Attardi L, Lowe S, Brugarolas J and Jacks T, Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. EMBO J 15: 3693-3701, 1996.
    • (1996) EMBO J , vol.15 , pp. 3693-3701
    • Donatella, A.L.1    Lowe, S.2    Brugarolas, J.3    Jacks, T.4
  • 43
    • 0030997647 scopus 로고    scopus 로고
    • Interleukin 1β converting enzyme-like proteases are essential for p53-mediated transcriptionally dependent apoptosis
    • Sabbatini P, Han J, Chiou S-K, Nicholson DW and White E, interleukin 1β converting enzyme-like proteases are essential for p53-mediated transcriptionally dependent apoptosis. Cell Growth Differ 8: 643-653, 1997.
    • (1997) Cell Growth Differ , vol.8 , pp. 643-653
    • Sabbatini, P.1    Han, J.2    Chiou, S.-K.3    Nicholson, D.W.4    White, E.5
  • 45
    • 0032557649 scopus 로고    scopus 로고
    • Identification of a novel p53 functional domain that is necessary for mediating apoptosis
    • Zhu JH, Zhou WJ, Jiang JY and Chen XB, Identification of a novel p53 functional domain that is necessary for mediating apoptosis. J Biol Chem 273: 13030-13036, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 13030-13036
    • Zhu, J.H.1    Zhou, W.J.2    Jiang, J.Y.3    Chen, X.B.4
  • 46
    • 0030798557 scopus 로고    scopus 로고
    • The polyproline region of p53 is required to activate apoptosis but not growth arrest
    • Sakamuro D, Sabbatini P, White E and Prendergast GC, The polyproline region of p53 is required to activate apoptosis but not growth arrest. Oncogens 15: 887-898, 1997.
    • (1997) Oncogens , vol.15 , pp. 887-898
    • Sakamuro, D.1    Sabbatini, P.2    White, E.3    Prendergast, G.C.4
  • 47
    • 0031056054 scopus 로고    scopus 로고
    • The murine C′-terminally alternatively spliced form of p53 induces attenuated apoptosis in myeloid cells
    • Almog N, Li R, Peled A, Schwartz D, Wolkowicz R, Goldfibnger N, Pei H and Rotter V, The murine C′-terminally alternatively spliced form of p53 induces attenuated apoptosis in myeloid cells. Mol Cell Biol 17: 713-722, 1997.
    • (1997) Mol Cell Biol , vol.17 , pp. 713-722
    • Almog, N.1    Li, R.2    Peled, A.3    Schwartz, D.4    Wolkowicz, R.5    Goldfinger, N.6    Pei, H.7    Rotter, V.8
  • 48
    • 0030021748 scopus 로고    scopus 로고
    • Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant
    • Rowan S, Ludwig RL, Haupt Y, BateS S, Lu X, Oren M and Vousden KH, Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant. EMBO J 15: 827-838, 1996.
    • (1996) EMBO J , vol.15 , pp. 827-838
    • Rowan, S.1    Ludwig, R.L.2    Haupt, Y.3    Bates, S.4    Lu, X.5    Oren, M.6    Vousden, K.H.7
  • 49
    • 0029092356 scopus 로고
    • Induction of apoptosis in HeLa cells by trans-activation-deficient p53
    • Haupt Y, Rowan S, Shaulian E, Vousden KH and Oren M, Induction of apoptosis in HeLa cells by trans-activation-deficient p53. Genes Dev 9: 2170-2183, 1995.
    • (1995) Genes Dev , vol.9 , pp. 2170-2183
    • Haupt, Y.1    Rowan, S.2    Shaulian, E.3    Vousden, K.H.4    Oren, M.5
  • 50
    • 0029028352 scopus 로고
    • Mutational analysis of the carboxy-terminal portion of p53 using both yeast and mammalian-cell assays in vivo
    • Ishioka C, Englert C, Winge P, Yan YX, Engelstein M and Friend SH, Mutational analysis of the carboxy-terminal portion of p53 using both yeast and mammalian-cell assays in vivo. Oncogene 10: 1485-1492, 1995.
    • (1995) Oncogene , vol.10 , pp. 1485-1492
    • Ishioka, C.1    Englert, C.2    Winge, P.3    Yan, Y.X.4    Engelstein, M.5    Friend, S.H.6
  • 51
    • 0028070989 scopus 로고
    • P53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
    • Caelles C, Helmberg A and Karin M, P53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 370: 220-223, 1994.
    • (1994) Nature , vol.370 , pp. 220-223
    • Caelles, C.1    Helmberg, A.2    Karin, M.3
  • 52
    • 0030983240 scopus 로고    scopus 로고
    • Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation
    • Yan Y, Shay JW, Wright WE and Mumby MC, Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation. J Biol Chem 272: 15220-15226, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 15220-15226
    • Yan, Y.1    Shay, J.W.2    Wright, W.E.3    Mumby, M.C.4
  • 53
    • 0030689782 scopus 로고    scopus 로고
    • The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo
    • Reinke V and Lozano G, The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo. Oncogene 15: 1527-1534, 1997.
    • (1997) Oncogene , vol.15 , pp. 1527-1534
    • Reinke, V.1    Lozano, G.2
  • 56
    • 0031036879 scopus 로고    scopus 로고
    • The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal
    • Prisco M, Hongo A, Rizzo MG, Sacchi A and Baserga R, The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal. Mol Cell Biol 17: 1084-1092, 1997.
    • (1997) Mol Cell Biol , vol.17 , pp. 1084-1092
    • Prisco, M.1    Hongo, A.2    Rizzo, M.G.3    Sacchi, A.4    Baserga, R.5
  • 57
    • 0031769052 scopus 로고    scopus 로고
    • P53 regulates insulin-like growth factor-I (IGF-I) receptor expression and IGF-I-induced tyrosine phosphorylation in an osteosarcoma cell line: Interaction between p53 and Sp1
    • Ohlsson C, Kley N, Werner H and LeRoith D, P53 regulates insulin-like growth factor-I (IGF-I) receptor expression and IGF-I-induced tyrosine phosphorylation in an osteosarcoma cell line: Interaction between p53 and Sp1. Endocrinology 139: 1101-1107, 1998.
    • (1998) Endocrinology , vol.139 , pp. 1101-1107
    • Ohlsson, C.1    Kley, N.2    Werner, H.3    LeRoith, D.4
  • 58
    • 0030978194 scopus 로고    scopus 로고
    • Regulation of p53-dependent apoptosis, transcriptional repression, and cell transformation by phosphorylation of the 55-kilodalton E1B protein of human adenovirus type 5
    • Teodoro JG and Branton PE, Regulation of p53-dependent apoptosis, transcriptional repression, and cell transformation by phosphorylation of the 55-kilodalton E1B protein of human adenovirus type 5. J Virol 71: 3620-3627, 1997.
    • (1997) J Virol , vol.71 , pp. 3620-3627
    • Teodoro, J.G.1    Branton, P.E.2
  • 60
    • 0030818891 scopus 로고    scopus 로고
    • Cell cycle specificity of Fas-mediated apoptosis in WIL-2 cells
    • Beletskaya IV, Nikonova LV and Beletsky IP, Cell cycle specificity of Fas-mediated apoptosis in WIL-2 cells. FEBS Lett 412: 91-93, 1997.
    • (1997) FEBS Lett , vol.412 , pp. 91-93
    • Beletskaya, I.V.1    Nikonova, L.V.2    Beletsky, I.P.3
  • 62
    • 0031943921 scopus 로고    scopus 로고
    • Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L
    • Aragane Y, Kulms D, Metze D, Wilkes G, Poppelmann B, Luger TA and Schwarz T, Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L. J Cell Biol 140: 171-182, 1998.
    • (1998) J Cell Biol , vol.140 , pp. 171-182
    • Aragane, Y.1    Kulms, D.2    Metze, D.3    Wilkes, G.4    Poppelmann, B.5    Luger, T.A.6    Schwarz, T.7
  • 63
    • 0031907378 scopus 로고    scopus 로고
    • P53 modulation of Fas/Apo-1 mediated apoptosis in a human renal cell carcinoma cell line
    • Miyake H, Hara I, Gohji K, Arakawa S and Kamidono S, P53 modulation of Fas/Apo-1 mediated apoptosis in a human renal cell carcinoma cell line. Int J Oncol 12: 469-473, 1998.
    • (1998) Int J Oncol , vol.12 , pp. 469-473
    • Miyake, H.1    Hara, I.2    Gohji, K.3    Arakawa, S.4    Kamidono, S.5
  • 65
    • 0030762122 scopus 로고    scopus 로고
    • Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases)
    • Los M, Herr I, Friesen C, Fulda S, Schulze-Osthoff K and Debatin KM, Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases). Blood 90: 3118-3129, 1997.
    • (1997) Blood , vol.90 , pp. 3118-3129
    • Los, M.1    Herr, I.2    Friesen, C.3    Fulda, S.4    Schulze-Osthoff, K.5    Debatin, K.M.6
  • 66
    • 0030683517 scopus 로고    scopus 로고
    • Treatment of the P815 murine mastocytoma with cisplatin or etoposide up-regulates cell-surface Fas (CD95) expression and increases sensitivity to anti-Fas antibody-mediated cytotoxicity and to lysis by anti-CD3-activated killer-T cells
    • Williams BA, Makrigiannis AP, Blay J and Hoskin DW, treatment of the P815 murine mastocytoma with cisplatin or etoposide up-regulates cell-surface Fas (CD95) expression and increases sensitivity to anti-Fas antibody-mediated cytotoxicity and to lysis by anti-CD3-activated killer-T cells. Int J Cancer 73: 416-423, 1997.
    • (1997) Int J Cancer , vol.73 , pp. 416-423
    • Williams, B.A.1    Makrigiannis, A.P.2    Blay, J.3    Hoskin, D.W.4
  • 67
    • 0030667376 scopus 로고    scopus 로고
    • Requirement for the CD95 receptor-ligand pathway in c-myc-induced apoptosis
    • Hueber A-O, Zörnig M, Lyon D, Suda T, Nagata S and Evan GI, Requirement for the CD95 receptor-ligand pathway in c-myc-induced apoptosis. Science 278: 1305-1309, 1997.
    • (1997) Science , vol.278 , pp. 1305-1309
    • Hueber, A.-O.1    Zörnig, M.2    Lyon, D.3    Suda, T.4    Nagata, S.5    Evan, G.I.6
  • 68
    • 0032499138 scopus 로고    scopus 로고
    • P53-dependent impairment of T-cell proliferation in FADD dominant-negative transgenic mice
    • Zörnig M, Hueber A-O and Evan G, P53-dependent impairment of T-cell proliferation in FADD dominant-negative transgenic mice. Curr Biol 8: 467-470, 1998.
    • (1998) Curr Biol , vol.8 , pp. 467-470
    • Zörnig, M.1    Hueber, A.-O.2    Evan, G.3
  • 69
    • 0030871457 scopus 로고    scopus 로고
    • P53-dependent DNA damage-induced apoptosis requires Fas/APO-1-independent activation of cpp32β
    • Fuchs EJ, McKenna KA and Bedi A, P53-dependent DNA damage-induced apoptosis requires Fas/APO-1-independent activation of CPP32β. Cancer Res 57: 2550-2554, 1997.
    • (1997) Cancer Res , vol.57 , pp. 2550-2554
    • Fuchs, E.J.1    McKenna, K.A.2    Bedi, A.3
  • 70
    • 0029081551 scopus 로고
    • Apoptosis of rat vascular smooth muscle cells is regulated by p53-dependent and -independent pathways
    • Bennett MR, Evan GI and Schwartz SM, Apoptosis of rat vascular smooth muscle cells is regulated by p53-dependent and -independent pathways. Circ Res 77: 266-273, 1995.
    • (1995) Circ Res , vol.77 , pp. 266-273
    • Bennett, M.R.1    Evan, G.I.2    Schwartz, S.M.3
  • 71
    • 0028263811 scopus 로고
    • C-Myc induced apoptosis in fibroblasts is inhibited by specific cytokines
    • Harrington EA, Bennett MR, Fanidi A and Evan GI, C-Myc induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J 13: 3286-3295, 1994.
    • (1994) EMBO J , vol.13 , pp. 3286-3295
    • Harrington, E.A.1    Bennett, M.R.2    Fanidi, A.3    Evan, G.I.4
  • 72
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A and Oren M, Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352: 345-347, 1991.
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 73
    • 0026523778 scopus 로고
    • Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line
    • Shaw P, Bovey R, Tardy S, Sahli R, Sordat B and Costa J, induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line. Proc Natl Acad Sci USA 89: 4495-4499, 1992.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4495-4499
    • Shaw, P.1    Bovey, R.2    Tardy, S.3    Sahli, R.4    Sordat, B.5    Costa, J.6
  • 74
    • 0027283604 scopus 로고
    • Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents
    • Lotem J and Sachs L, Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents. Blood 82: 1092-1096, 1993.
    • (1993) Blood , vol.82 , pp. 1092-1096
    • Lotem, J.1    Sachs, L.2
  • 75
    • 0026690076 scopus 로고
    • Regulation of leukaemic cells by interleukin 6 and leukaemia inhibitory factor
    • Lotem J and Sachs L, Regulation of leukaemic cells by interleukin 6 and leukaemia inhibitory factor. Ciba Found Symp 167: 80-88, 1992.
    • (1992) Ciba Found Symp , vol.167 , pp. 80-88
    • Lotem, J.1    Sachs, L.2
  • 76
    • 0032576768 scopus 로고    scopus 로고
    • ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
    • Aladjem MI, Spike BT, Rodewald LW, Hope TJ, Klemm M, Jaenisch R and Wahl GM, ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage. Curr Biol 8: 145-155, 1998.
    • (1998) Curr Biol , vol.8 , pp. 145-155
    • Aladjem, M.I.1    Spike, B.T.2    Rodewald, L.W.3    Hope, T.J.4    Klemm, M.5    Jaenisch, R.6    Wahl, G.M.7
  • 78
    • 0028047723 scopus 로고
    • The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice
    • Merritt AJ, Potten CS, Kemp CJ, Hickman JA, Balmain A, Lane DP and Hall PA, The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res 54: 614-617, 1994.
    • (1994) Cancer Res , vol.54 , pp. 614-617
    • Merritt, A.J.1    Potten, C.S.2    Kemp, C.J.3    Hickman, J.A.4    Balmain, A.5    Lane, D.P.6    Hall, P.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.