Roles of p300, pocket proteins, and hTBP in E1A-mediated transcriptional regulation and inhibition of p53 transactivation activity

Journal of Cellular Biochemistry

Volumn 66, Issue 3, 1997, Pages 277-285

  Sang, Nianli ^a,b   Avantaggiati, Maria Laura ^c   Giordano, Antonio ^a,d  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c UNIVERSITY AT BUFFALO   (United States)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

p107; p130 Rb2; pRb; TBP; Transcription

Indexed keywords

PROTEIN P53; TRANSCRIPTION FACTOR;

ADENOVIRUS; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; GENE ACTIVATION; GENE EXPRESSION REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN SYNTHESIS REGULATION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

ADENOVIRUS E1A PROTEINS; ANIMALS; BINDING SITES; DNA-BINDING PROTEINS; E1A-ASSOCIATED P300 PROTEIN; MICE; NUCLEAR PROTEINS; PEPTIDE FRAGMENTS; REPRESSOR PROTEINS; RETINOBLASTOMA PROTEIN; TATA-BOX BINDING PROTEIN; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTOR TFIIB; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

ADENOVIRIDAE;

EID: 0030753187     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19970901)66:3<277::AID-JCB1>3.0.CO;2-M     Document Type: Article

References (40)

1. Bannister AJ, Kouzarides T (1995): CBP-induced stimulation of c-Fos activity is abrogated by E1A. EMBO J 14:4758-4762.
2. Billon N, van Grunsven LA, Rudkin BB (1996): The Cdk inhibitor p21(WAF1/CIP1) is induced through a p300-dependent mechanism during NGF-mediated neuronal differentiation of PC12 cells. Oncogene 13:2047-2054.
3. Caruso M, Martelli F, Giordano A, Felsani A (1993): Regulation of MyoD gene transcription and protein function by the transforming domains of the adenovirus E1A oncoprotein. Oncogene 8:267-278.
4. Claudio PP, Howard CM, Baldi A, De Luca A, Fu Y, Condorelli G, Sun Y, Colburn N, Calabretta B, Giordano A (1994): p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107. Cancer Res 54:5556-5560.
5. Datta PK, Bagchi S (1994): Repression of transforming growth factor beta 1 promoter by the adenovirus oncogene E1A. Identification of a unique GC-rich sequence as a target for E1A repression. J Biol Chem 269:25392-25399.
6. Debbas M, White E (1993): Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev 7:546-554.
7. Eckner R, Ewen ME, Newsome D, Gerdes M, DeCaprio JA, Lawrence JB, Livingston DM (1994): Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev 8:869-884.
8. Eckner R, Yao TP, Oldread E, Livingston DM (1996): Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and β-cell differentiation. Genes Dev 10:2478-2490.
9. El-Deiry WS, Tokino JT, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B (1993): WAF1, a potential mediator of p53 tumor suppression. Cell 75:817-825.
10. Elledge SJ, Harper W (1994): Cdk inhibitors: On the threshold of checkpoints and development. Curr Opin Cell Biol 6:847-852.
11. Fornace AJ, Jr. (1992): Mammalian genes induced by radiation; activation of genes associated with growth control. Annu Rev Genet 26:507-526.
12. Giordano A, Whyte P, Harlow E, Franza BR Jr, Beach D, Draetta G (1989): A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells. Cell 58:981-990.
13. Haas-Kogan DA, Kogan SC, Levi D, Dazin P, T'Ang A, Fung Y-KT, Israel MA (1995): Inhibition of apoptosis by the retinoblastoma gene product. EMBO J 14:461-472.
14. Lane DP (1992): p53: Guardian of the genome. Nature 358:15-16.
15. Lee JS, See RH, Deng T, Shi Y (1996): Adenovirus E1A downregulates cJun-and JunB-mediated transcription by targeting their coactivator p300. Mol Cell Biol 16:4312-4326.
16. Li Y, Graham C, Lacy S, Duncan AM, Whyte P (1993): The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclin A and E. Genes Dev 7:2366-2377.
17. Lowe SW, Ruley HE (1993): Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis. Genes Dev 7:535-545.
18. MacLachlan T, Sang N, Giordano A (1995): Cyclins, cyclin-dependent kinases and cdk inhibitors: Implications in cell cycle control and cancer. Crit Rev Eukaryotic Gene Expression 5:127-156.
19. Mayol X, Grana X, Baldi A, Sang N, Hu Q, Giordano A (1993): Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain. Oncogene 8:2561-2566.
20. Miyashita T, Reed JC (1995): Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80:293-299.
21. Miyashita T, Harigai M, Hanada M, Reed JC (1994): Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res 54:3131-3135.
22. Moran E (1993): DNA tumor virus transforming proteins and the cell cycle. Curr Opin Genet Dev 3:63-70.
23. Offringa R, Gebel S, van Dam H, Timmers M, Smits A, Zwart R, Stein B, Bos JL, van der Eb A, Herrlich P (1990): A novel function of the transforming domain of E1a: Repression of AP-1 activity. Cell 62:527-538.
24. Ogryzko VV, Schiltz RL, Russanova V, Howard BH, Nakatani Y (1996): The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87:953-959.
25. Puri PL, Avantaggiati ML, Balsano C, Sang N, Graessmann A, Giordano A, Levrero M (1997): p300 is a cofactor for MyoD-dependent cell cycle arrest and muscle specific genes transcription. EMBO J 16:369-383.
26. Sabbatini P, Lin J, Levine AJ, White E (1995): Essential role for p53-mediated transcription in E1A-induced apoptosis. Genes Dev 9:2184-2192.
27. Sala A, Nicolaides NC, Engelhar A, Bellon T, Lawe DC, Arnold A, Grana X, Giordano A, Calabretta B (1994): Correlation between E2F-1 requirement in the S phase and E2F-1 transactivation of cell cycle-related genes in human cells. Cancer Res 54:1402-1406.
28. Sang N, Giordano A (1997): The extreme N-terminal transforming region of the E1A oncoprotein specifically associates with a new set of cellular proteins. J Cell Physiol 170:182-191.
29. Sang N, Baldi A, Giordano A (1995): The roles of tumor suppressors pRb and p53 in cell proliferation and cancer. Mol Cell Differ 3:1-29.
30. Sang N, Claudio PP, Fu Y, Horikoshi N, Graeven U, Weinmann R, Giordano A (in press): The N-terminal transforming region of E1A contains two overlapping but distinct transactivation domains. DNA Cell Biol.
31. Steegenga WT, Laar TV, Riteco N, Mandarino A, Shvarts A, van der Eb AJ, Jochemsen AG (1996): Adenovirus E1A proteins inhibit activation of transcription by p53. Mol Cell Biol 16:2101-2109.
32. Steinman RA, Hoffman B, Iro A, Guillouf C, Liebermann DA, El-Houseini ME: (1994) Induction of p21 (WAF-1/ CIP1) during differentiation. Oncogene 9:3389-3396.
33. Tang X, Li HO, Sakatsume O, Ohta T, Tsutsui H, Smit AFA, Horikoshi M, Kourilsky P, Israel A, Gachelin G, Yokoyama K (1995): Cooperatively between an upstream TATA-like sequence and a CAA repeated element mediates E1A-dependent negative repression of the H-2Kb class gene. J Biol Chem 270:2327-2336.
34. Tsang SX, Morris GF, Lu M, Morris CB (1996): TATA-dependent repression of human immunodeficiency virus type-1 transcription by the adenovirus E1A243R oncoprotein. Oncogene 12:819-826.
35. Wang HGH, Rikitake Y, Carter MC, Yaciuk P, Abraham SE, Zerler B, Moran E (1993): Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growth. J Virol 67:476-488.
36. Wu X, Levine AJ (1994): p53 and E2F-1 cooperate to mediate apoptosis. Proc Natl Acad Sci U S A 91:3602-3606.
37. Yang XJ, Ogryzko VY, Nishikawa J, Howard BH, Nakatani Y (1996): A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 382:319-324.
38. Yuan W, Condorelli G, Caruso M, Felsani A, Giordano A (1996): Human p300 protein is a coactivator for the transcription factor MyoD. J Biol Chem 271:9009-9013.
39. Zhan Q, Lord KA, Alamo I Jr, Hollander MC, Carrier F, Ron D, Kohn KW, Hoffman B, Liebermann DA, Fornace AJ Jr (1994): The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth. Mol Cell Biol 14:2361-2371.
40. Zhu L, Van Den Heuvel S, Helin K, Fattaey A, Ewen M, Livingston D, Dyson N, Harlow E (1993): Inhibition of cell proliferation by 107, a relative of the retinoblastoma protein. Genes Dev 7:1111-1125.