-
1
-
-
0031975821
-
The relative role of lymphocyte granule exocytosis versus death receptor-mediated cytotoxicity in viral pathophysiology
-
1 Smyth MJ, Trapani JA. The relative role of lymphocyte granule exocytosis versus death receptor-mediated cytotoxicity in viral pathophysiology. J. Virol. 1998; 72: 1-9.
-
(1998)
J. Virol.
, vol.72
, pp. 1-9
-
-
Smyth, M.J.1
Trapani, J.A.2
-
2
-
-
0031899584
-
Dual mechanisms of apoptosis induction by cytotoxic lymphocytes
-
2 Trapani JA. Dual mechanisms of apoptosis induction by cytotoxic lymphocytes. Int. Rev. Cytol. 1998; 182: 111-92.
-
(1998)
Int. Rev. Cytol.
, vol.182
, pp. 111-192
-
-
Trapani, J.A.1
-
3
-
-
0030892234
-
Apoptosis by death factor
-
3 Nagata S. Apoptosis by death factor. Cell 1997; 88: 355-65.
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
4
-
-
0026568919
-
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
-
4 Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992; 356: 314-17.
-
(1992)
Nature
, vol.356
, pp. 314-317
-
-
Watanabe-Fukunaga, R.1
Brannan, C.I.2
Copeland, N.G.3
Jenkins, N.A.4
Nagata, S.5
-
5
-
-
0028429962
-
The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster
-
5 Lynch DH, Watson ML, Alderson MR et al. The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster. Immunity 1994; 1: 131-6.
-
(1994)
Immunity
, vol.1
, pp. 131-136
-
-
Lynch, D.H.1
Watson, M.L.2
Alderson, M.R.3
-
6
-
-
0028223847
-
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
-
6 Takahashi T, Tanaka M, Brannan CI et al. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 1994; 76: 969-76.
-
(1994)
Cell
, vol.76
, pp. 969-976
-
-
Takahashi, T.1
Tanaka, M.2
Brannan, C.I.3
-
7
-
-
0026471742
-
Genetic analysis of MRL-lpr mice: Relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci
-
7 Watson ML, Rao JK, Gilkeson GS et al. Genetic analysis of MRL-lpr mice: Relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. J. Exp. Med. 1992; 176: 1645-56.
-
(1992)
J. Exp. Med.
, vol.176
, pp. 1645-1656
-
-
Watson, M.L.1
Rao, J.K.2
Gilkeson, G.S.3
-
8
-
-
0028170376
-
Structure and mechanism of interleukin-1 beta converting enzyme
-
8 Wilson KP, Black JA, Thomson JA et al. Structure and mechanism of interleukin-1 beta converting enzyme. Nature 1994; 370: 270-5.
-
(1994)
Nature
, vol.370
, pp. 270-275
-
-
Wilson, K.P.1
Black, J.A.2
Thomson, J.A.3
-
9
-
-
0028107827
-
Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: A (p20/p10), 2 homodimer
-
9 Walker NP, Talanian RV, Brady KD et al. Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: A (p20/p10), 2 homodimer. Cell 1994; 78: 343-52.
-
(1994)
Cell
, vol.78
, pp. 343-352
-
-
Walker, N.P.1
Talanian, R.V.2
Brady, K.D.3
-
10
-
-
15844393657
-
The three-dimensional structure of apopain/CPP.32, a key mediator of apoptosis
-
10 Rotonda J, Nicholson DW, Fazil KM et al. The three-dimensional structure of apopain/CPP.32, a key mediator of apoptosis. Nat. Struct. Biol. 1996; 3: 619-25.
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 619-625
-
-
Rotonda, J.1
Nicholson, D.W.2
Fazil, K.M.3
-
12
-
-
0026517239
-
Molecular cloning of the interleukin-1 beta converting enzyme
-
12 Cerretti DP, Kozlosky CJ, Mosley B et al. Molecular cloning of the interleukin-1 beta converting enzyme. Science 1992; 256: 97-100.
-
(1992)
Science
, vol.256
, pp. 97-100
-
-
Cerretti, D.P.1
Kozlosky, C.J.2
Mosley, B.3
-
13
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
-
13 Thornberry NA, Bull HG, Calaycay JR et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature 1992; 356: 768-74.
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
-
14
-
-
0030897988
-
Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases
-
14 Margolin N, Raybuck SA, Wilson KP et al. Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases. J. Biol. Chem. 1997; 272: 7223-8.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7223-7228
-
-
Margolin, N.1
Raybuck, S.A.2
Wilson, K.P.3
-
15
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
-
15 Thornberry NA, Rano TA, Peterson EP et al. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 1997; 272: 17907-11.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17907-17911
-
-
Thornberry, N.A.1
Rano, T.A.2
Peterson, E.P.3
-
16
-
-
0030916417
-
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
-
16 Liu X, Zou H, Slaughter C, Wang X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 1997; 89: 175-84.
-
(1997)
Cell
, vol.89
, pp. 175-184
-
-
Liu, X.1
Zou, H.2
Slaughter, C.3
Wang, X.4
-
17
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
17 Nicholson DW, Ali A, Thornberry NA et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 1995; 376: 37-43.
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
-
18
-
-
0029890823
-
Apopain/CPP32 cleaves proteins that are essential for cellular repair: A fundamental principle of apoptotic death
-
18 Casciola-Rosen L, Nicholson DW, Chong T et al. Apopain/CPP32 cleaves proteins that are essential for cellular repair: A fundamental principle of apoptotic death. J. Exp. Med. 1996; 183: 1957-64.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1957-1964
-
-
Casciola-Rosen, L.1
Nicholson, D.W.2
Chong, T.3
-
19
-
-
0031888955
-
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
-
Erratum: Nature 1998; 393: 396
-
19 Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD [Erratum: Nature 1998; 393: 396]. Nature 1998; 391: 43-50.
-
(1998)
Nature
, vol.391
, pp. 43-50
-
-
Enari, M.1
Sakahira, H.2
Yokoyama, H.3
Okawa, K.4
Iwamatsu, A.5
Nagata, S.6
-
20
-
-
0030058584
-
Dynamic changes of NuMA during the cell cycle and possible appearance of a truncated form of NuMA during apoptosis
-
20 Hsu HL, Yeh NH. Dynamic changes of NuMA during the cell cycle and possible appearance of a truncated form of NuMA during apoptosis. J. Cell Sci. 1996; 109: 277-88.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 277-288
-
-
Hsu, H.L.1
Yeh, N.H.2
-
21
-
-
0029758833
-
Cleavage of lamin A by Mch2 alpha but not CPP32: Multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis
-
21 Takahashi A, Alnemri ES, LazebnikYA et al. Cleavage of lamin A by Mch2 alpha but not CPP32: Multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis. Proc. Natl Acad. Sci. USA 1996; 93: 8395-400.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 8395-8400
-
-
Takahashi, A.1
Alnemri, E.S.2
-
22
-
-
0029959632
-
Specific cleavage of alpha-fodrin during Fas-and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1beta-converting enzyme/Ced-3 protease distinct from the poly (ADP-ribose) polymerase protease
-
22 Cryns VL, Bergeron L, Zhu H, Li H, Yuan J. Specific cleavage of alpha-fodrin during Fas-and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1beta-converting enzyme/Ced-3 protease distinct from the poly (ADP-ribose) polymerase protease. J. Biol. Chem. 1996; 271: 31 277-82.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31277-31282
-
-
Cryns, V.L.1
Bergeron, L.2
Zhu, H.3
Li, H.4
Yuan, J.5
-
23
-
-
0030770449
-
Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis
-
23 Caulin C, Salvesen GS, Oshima RG. Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis. J Cell Biol. 1997; 138: 1379-94.
-
(1997)
J Cell Biol.
, vol.138
, pp. 1379-1394
-
-
Caulin, C.1
Salvesen, G.S.2
Oshima, R.G.3
-
24
-
-
0030002801
-
Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP.32
-
24 Slee EA, Zhu H, Chow SC, MacFarlane M, Nicholson DW, Cohen GM. Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP.32. Biochem. J. 1996; 315: 21-4.
-
(1996)
Biochem. J.
, vol.315
, pp. 21-24
-
-
Slee, E.A.1
Zhu, H.2
Chow, S.C.3
MacFarlane, M.4
Nicholson, D.W.5
Cohen, G.M.6
-
25
-
-
0028885998
-
Multiple proteases are involved in thymocyte apoptosis
-
25 Zhivotovsky B, Gahm A, Ankarcrona M, Nicotera P, Orrenius S. Multiple proteases are involved in thymocyte apoptosis. Exp. Cell Res. 1995; 221: 404-12.
-
(1995)
Exp. Cell Res.
, vol.221
, pp. 404-412
-
-
Zhivotovsky, B.1
Gahm, A.2
Ankarcrona, M.3
Nicotera, P.4
Orrenius, S.5
-
26
-
-
0028970060
-
Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
-
26 Trinchieri G. Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 1995; 13: 251-76.
-
(1995)
Annu. Rev. Immunol.
, vol.13
, pp. 251-276
-
-
Trinchieri, G.1
-
27
-
-
0025837169
-
The antiviral activity of immune CD8+ T cells is dependent on interferon-gamma
-
27 Ruby J, Ramshaw I. The antiviral activity of immune CD8+ T cells is dependent on interferon-gamma. Lymphokine Cytokine Res. 1991; 10: 353-8.
-
(1991)
Lymphokine Cytokine Res.
, vol.10
, pp. 353-358
-
-
Ruby, J.1
Ramshaw, I.2
-
28
-
-
0030711669
-
Cytokines and immunity to viral infections
-
28 Ramshaw IA, Ramsay AJ, Karupiah G, Rolph MS, Mahalingam S, Ruby JC. Cytokines and immunity to viral infections. Immunol. Rev. 1997; 159: 119-35.
-
(1997)
Immunol. Rev.
, vol.159
, pp. 119-135
-
-
Ramshaw, I.A.1
Ramsay, A.J.2
Karupiah, G.3
Rolph, M.S.4
Mahalingam, S.5
Ruby, J.C.6
-
29
-
-
0027215921
-
Importance of interferons in recovery from mousepox
-
29 Karupiah G, Fredrickson TN, Holmes KL, Khairallah LH, Buller RM. Importance of interferons in recovery from mousepox. J. Virol. 1993; 67: 4214-26.
-
(1993)
J. Virol.
, vol.67
, pp. 4214-4226
-
-
Karupiah, G.1
Fredrickson, T.N.2
Holmes, K.L.3
Khairallah, L.H.4
Buller, R.M.5
-
30
-
-
0014633288
-
Pathogenesis of lesions in lymphoid tissue of mice infected with lymphocytic choriomeningitis (LCM) virus
-
30 Mims CA, Tosolini FA. Pathogenesis of lesions in lymphoid tissue of mice infected with lymphocytic choriomeningitis (LCM) virus. Br. J. Exp. Pathol. 1969; 50: 584-92.
-
(1969)
Br. J. Exp. Pathol.
, vol.50
, pp. 584-592
-
-
Mims, C.A.1
Tosolini, F.A.2
-
31
-
-
0018753961
-
MHC-restricted cytotoxic T cells: Studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness
-
31 Zinkernagel RM, Doherty PC. MHC-restricted cytotoxic T cells: Studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness. Adv. Immunol. 1979; 27: 51-177.
-
(1979)
Adv. Immunol.
, vol.27
, pp. 51-177
-
-
Zinkernagel, R.M.1
Doherty, P.C.2
-
32
-
-
0025787430
-
Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure
-
32 Odermatt B, Eppler M, Leist TP, Hengartner H, Zinkernagel RM. Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure. Proc. Natl Acad. Sci. USA 1991; 88: 8252-6.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 8252-8256
-
-
Odermatt, B.1
Eppler, M.2
Leist, T.P.3
Hengartner, H.4
Zinkernagel, R.M.5
-
33
-
-
0029772017
-
M-T2: A poxvirus TNF receptor homologue with dual activities
-
33 Sedger L, McFadden G. M-T2: A poxvirus TNF receptor homologue with dual activities. Immunol. Cell Biol. 1996; 74: 538-45.
-
(1996)
Immunol. Cell Biol.
, vol.74
, pp. 538-545
-
-
Sedger, L.1
McFadden, G.2
-
34
-
-
0031041650
-
Distinct domains of M-T2, the myxoma virus tumor necrosis factor (TNF) receptor homolog, mediate extracellular TNF binding and intracellular apoptosis inhibition
-
34 Schreiber M, Sedger L, McFadden G. Distinct domains of M-T2, the myxoma virus tumor necrosis factor (TNF) receptor homolog, mediate extracellular TNF binding and intracellular apoptosis inhibition. J. Virol. 1997; 71: 2171-81.
-
(1997)
J. Virol.
, vol.71
, pp. 2171-2181
-
-
Schreiber, M.1
Sedger, L.2
McFadden, G.3
-
35
-
-
0025266516
-
A 14,500 MW protein is coded by region E3 of group C human adenoviruses
-
35 Tollefson AE, Krajcsi P, Pursley MH, Gooding LR, Wold WS. A 14,500 MW protein is coded by region E3 of group C human adenoviruses. Virology 1990; 175: 19-29.
-
(1990)
Virology
, vol.175
, pp. 19-29
-
-
Tollefson, A.E.1
Krajcsi, P.2
Pursley, M.H.3
Gooding, L.R.4
Wold, W.S.5
-
36
-
-
0025162187
-
A 10,400-molecular-weight membrane protein is coded by region E3 of adenovirus
-
36 Tollefson AE, Krajcsi P, Yei SP, Carlin CR, Wold WS. A 10,400-molecular-weight membrane protein is coded by region E3 of adenovirus. J. Virol. 1990; 64: 794-801.
-
(1990)
J. Virol.
, vol.64
, pp. 794-801
-
-
Tollefson, A.E.1
Krajcsi, P.2
Yei, S.P.3
Carlin, C.R.4
Wold, W.S.5
-
37
-
-
19244368330
-
Forced degradation of Fas inhibits apoptosis in adenovirus-infected cells
-
37 Tollefson AE, Hermiston TW, Lichtenstein DL et al. Forced degradation of Fas inhibits apoptosis in adenovirus-infected cells. Nature 1998; 392: 726-30.
-
(1998)
Nature
, vol.392
, pp. 726-730
-
-
Tollefson, A.E.1
Hermiston, T.W.2
Lichtenstein, D.L.3
-
38
-
-
0032544013
-
The adenovirus E3/10.4K-14.5K proteins down-modulate the apoptosis receptor Fas/Apo-1 by inducing its internalization
-
38 Elsing A, Burgert HG. The adenovirus E3/10.4K-14.5K proteins down-modulate the apoptosis receptor Fas/Apo-1 by inducing its internalization. Proc. Natl Acad. Sci. USA 1998; 95: 10072-7.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 10072-10077
-
-
Elsing, A.1
Burgert, H.G.2
-
39
-
-
0030970013
-
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
-
39 Thome M, Schneider P, Hofmann K et al. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature 1997; 386: 517-21.
-
(1997)
Nature
, vol.386
, pp. 517-521
-
-
Thome, M.1
Schneider, P.2
Hofmann, K.3
-
40
-
-
0030827216
-
Bovine herpesvirus 4 BORFE2 protein inhibits Fas-and tumor necrosis factor receptor 1-induced apoptosis and contains death effector domains shared with other gamma-2 herpesviruses
-
40 Wang GH, Berlin J, Wang Y et al. Bovine herpesvirus 4 BORFE2 protein inhibits Fas-and tumor necrosis factor receptor 1-induced apoptosis and contains death effector domains shared with other gamma-2 herpesviruses. J. Virol. 1997; 71: 8928-32.
-
(1997)
J. Virol.
, vol.71
, pp. 8928-8932
-
-
Wang, G.H.1
Berlin, J.2
Wang, Y.3
-
41
-
-
12644286556
-
Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas-and TNFR1-induced apoptosis
-
41 Bertin J, Armstrong RC, Ottilie S et al. Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas-and TNFR1-induced apoptosis. Proc. Natl Acad. Sci. USA 1997; 94: 1172-6.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 1172-1176
-
-
Bertin, J.1
Armstrong, R.C.2
Ottilie, S.3
-
42
-
-
0029120118
-
CrmA, a poxvirus-encoded serpin, inhibits cytotoxic T-lymphocyte-mediated apoptosis
-
42 Tewari M, Telford WG, Miller RA, Dixit VM. CrmA, a poxvirus-encoded serpin, inhibits cytotoxic T-lymphocyte-mediated apoptosis. J. Biol. Chem. 1995; 270: 22 705-8.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 22705-22708
-
-
Tewari, M.1
Telford, W.G.2
Miller, R.A.3
Dixit, V.M.4
-
43
-
-
0029114963
-
Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway
-
43 Miura M, Friedlander RM, Yuan J. Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway. Proc. Natl Acad. Sci. USA 1995; 92: 8318-22.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 8318-8322
-
-
Miura, M.1
Friedlander, R.M.2
Yuan, J.3
-
44
-
-
0026728952
-
Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme
-
44 Ray CA, Black RA, Kronheim SR et al. Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme. Cell 1992; 69: 597-604.
-
(1992)
Cell
, vol.69
, pp. 597-604
-
-
Ray, C.A.1
Black, R.A.2
Kronheim, S.R.3
-
45
-
-
0029808217
-
Differential inhibition of the Fas-and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein
-
45 Macen JL, Garner RS, Musy PY et al. Differential inhibition of the Fas-and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein. Proc. Natl Acad. Sci. USA 1996; 93: 9108-13.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 9108-9113
-
-
Macen, J.L.1
Garner, R.S.2
Musy, P.Y.3
-
46
-
-
0028955325
-
Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A
-
46 Quan LT, Caputo A, Bleackley RC, Pickup DJ, Salvesen GS. Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A. J. Biol. Chem. 1995; 270: 10 377-9.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 10377-10379
-
-
Quan, L.T.1
Caputo, A.2
Bleackley, R.C.3
Pickup, D.J.4
Salvesen, G.S.5
-
47
-
-
0029839388
-
Characterization of a myxoma virus-encoded serpin-like protein with activity against interleukin-1 beta-converting enzyme
-
47 Petit F, Bertagnoli S, Gelfi J, Fassy F, Boucraut-Baralon C, Milon A. Characterization of a myxoma virus-encoded serpin-like protein with activity against interleukin-1 beta-converting enzyme. J. Virol. 1996; 70: 5860-6.
-
(1996)
J. Virol.
, vol.70
, pp. 5860-5866
-
-
Petit, F.1
Bertagnoli, S.2
Gelfi, J.3
Fassy, F.4
Boucraut-Baralon, C.5
Milon, A.6
-
48
-
-
0027537461
-
An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif
-
48 Crook NE, Clem RJ, Miller LK. An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif. J. Virol. 1993; 67: 2168-74.
-
(1993)
J. Virol.
, vol.67
, pp. 2168-2174
-
-
Crook, N.E.1
Clem, R.J.2
Miller, L.K.3
-
49
-
-
0027394788
-
Identification and preliminary characterization of a protein motif related to the zinc finger
-
49 Lovering R, Hanson IM, Borden KL et al. Identification and preliminary characterization of a protein motif related to the zinc finger. Proc. Natl Acad. Sci. USA 1993; 90: 2112-16.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 2112-2116
-
-
Lovering, R.1
Hanson, I.M.2
Borden, K.L.3
-
50
-
-
0027990727
-
Control of programmed cell death by the baculovirus genes p35 and iap
-
50 Clem RJ, Miller LK. Control of programmed cell death by the baculovirus genes p35 and iap. Mol. Cell. Biol. 1994; 14: 5212-22.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 5212-5222
-
-
Clem, R.J.1
Miller, L.K.2
-
51
-
-
0032522738
-
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
-
51 Deveraux QL, Roy N, Stennicke HR et al. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J. 1998; 17: 2215-23.
-
(1998)
EMBO J.
, vol.17
, pp. 2215-2223
-
-
Deveraux, Q.L.1
Roy, N.2
Stennicke, H.R.3
-
52
-
-
0027264124
-
An African swine fever virus gene with similarity to the proto-oncogene bcl-2 and the Epstein-Barr virus gene BHRF1
-
52 Neilan JG, Lu Z, Afonso CL, Kutish GF, Sussman MD, Rock DL. An African swine fever virus gene with similarity to the proto-oncogene bcl-2 and the Epstein-Barr virus gene BHRF1. J. Virol. 1993; 67: 4391-4.
-
(1993)
J. Virol.
, vol.67
, pp. 4391-4394
-
-
Neilan, J.G.1
Lu, Z.2
Afonso, C.L.3
Kutish, G.F.4
Sussman, M.D.5
Rock, D.L.6
-
53
-
-
0031470626
-
Baculovirus inhibitors of apoptosis (IAPs) block activation of Sf-caspase-1
-
53 Seshagiri S, Miller LK. Baculovirus inhibitors of apoptosis (IAPs) block activation of Sf-caspase-1. Proc. Natl Acad. Sci. USA 1997; 94: 13 606-11.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 13606-13611
-
-
Seshagiri, S.1
Miller, L.K.2
-
54
-
-
0032575309
-
Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex
-
54 Zhou Q, Krebs JF, Snipas SJ et al. Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex. Biochemistry 1998; 37: 10 757-65.
-
(1998)
Biochemistry
, vol.37
, pp. 10757-10765
-
-
Zhou, Q.1
Krebs, J.F.2
Snipas, S.J.3
-
55
-
-
0030907965
-
Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases
-
55 Sarin A, Williams MS, Alexander-Miller MA, Berzofsky JA, Zacharchuk CM, Henkart PA. Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases. Immunity 1997; 6: 209-15.
-
(1997)
Immunity
, vol.6
, pp. 209-215
-
-
Sarin, A.1
Williams, M.S.2
Alexander-Miller, Ma.3
Berzofsky, J.A.4
Zacharchuk, C.M.5
Henkart, P.A.6
-
56
-
-
0031054439
-
Kaposi's sarcoma-associated herpesvirus encodes a functional bcl-2 homologue
-
56 Sarid R, Sato T, Bohenzky RA, Russo JJ, Chang Y. Kaposi's sarcoma-associated herpesvirus encodes a functional bcl-2 homologue. Nat. Med. 1997; 3: 293-8.
-
(1997)
Nat. Med.
, vol.3
, pp. 293-298
-
-
Sarid, R.1
Sato, T.2
Bohenzky, R.A.3
Russo, J.J.4
Chang, Y.5
-
57
-
-
0030893693
-
Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogene
-
57 Nava VE, Cheng EH, Veliuona M et al. Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogene. J. Virol. 1997; 71: 4118-22.
-
(1997)
J. Virol.
, vol.71
, pp. 4118-4122
-
-
Nava, V.E.1
Cheng, E.H.2
Veliuona, M.3
-
58
-
-
0025943729
-
The E1B 19,000-molecular-weight protein of group C adenoviruses prevents tumor necrosis factor cytolysis of human cells but not of mouse cells
-
58 Gooding LR, Aquino L, Duerksen-Hughes PJ et al. The E1B 19,000-molecular-weight protein of group C adenoviruses prevents tumor necrosis factor cytolysis of human cells but not of mouse cells. J. Virol. 1991; 65: 3083-94.
-
(1991)
J. Virol.
, vol.65
, pp. 3083-3094
-
-
Gooding, L.R.1
Aquino, L.2
Duerksen-Hughes, P.J.3
-
59
-
-
0031017578
-
A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpes-virus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak
-
59 Cheng EH, Nicholas J, Bellows DS et al. A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpes-virus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak. Proc. Natl Acad, Sci. USA 1997; 94: 690-4.
-
(1997)
Proc. Natl Acad, Sci. USA
, vol.94
, pp. 690-694
-
-
Cheng, E.H.1
Nicholas, J.2
Bellows, D.S.3
-
60
-
-
0027260656
-
Epstein-Barr virus-coded BIIRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death
-
60 Henderson S, Huen D, Rowe M, Dawson C, Johnson G, Rickinson A. Epstein-Barr virus-coded BIIRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death. Proc. Natl Acad. Sci. USA 1993; 90: 8479-83.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 8479-8483
-
-
Henderson, S.1
Huen, D.2
Rowe, M.3
Dawson, C.4
Johnson, G.5
Rickinson, A.6
-
61
-
-
0026049728
-
Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins
-
61 White E, Cipriani R, Sabbatini P, Denton A. Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins. J Virol. 1991; 65: 2968-78.
-
(1991)
J Virol.
, vol.65
, pp. 2968-2978
-
-
White, E.1
Cipriani, R.2
Sabbatini, P.3
Denton, A.4
-
62
-
-
0026639932
-
The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins
-
Erratum: Proc. Natl Acad. Sci. USA 1992; 89: 9974
-
62 Rao L, Debbas M, Sabbatini P, Hockenbery D, Korsmeyer S, White E. The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins [Erratum: Proc. Natl Acad. Sci. USA 1992; 89: 9974]. Proc. Natl Acad. Sci. USA 1992; 89: 7742-6.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 7742-7746
-
-
Rao, L.1
Debbas, M.2
Sabbatini, P.3
Hockenbery, D.4
Korsmeyer, S.5
White, E.6
-
63
-
-
0028059445
-
Functional complementation of the adenovirus E1B 19-kilodalton protein with Bcl-2 in the inhibition of apoptosis in infected cells
-
63 Chiou SK, Tseng CC, Rao L, White E. Functional complementation of the adenovirus E1B 19-kilodalton protein with Bcl-2 in the inhibition of apoptosis in infected cells. J. Virol. 1994; 68: 6553-66.
-
(1994)
J. Virol.
, vol.68
, pp. 6553-6566
-
-
Chiou, S.K.1
Tseng, C.C.2
Rao, L.3
White, E.4
-
64
-
-
0032100771
-
E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE
-
64 Perez D, White E. E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE. J. Cell Biol. 1998; 141: 1255-66.
-
(1998)
J. Cell Biol.
, vol.141
, pp. 1255-1266
-
-
Perez, D.1
White, E.2
-
65
-
-
0031655434
-
E1B 19,000-molecular-weight protein interacts with and inhibits CED-4-dependent, FLICE-mediated apoptosis
-
65 Han J, Wallen HD, Nunez G, White E. E1B 19,000-molecular-weight protein interacts with and inhibits CED-4-dependent, FLICE-mediated apoptosis. Mol. Cell. Biol. 1998; 18: 6052-62.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6052-6062
-
-
Han, J.1
Wallen, H.D.2
Nunez, G.3
White, E.4
-
66
-
-
0032524656
-
Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence
-
66 Yasuda M, Theodorakis P, Subramanian T, Chinnadurai G. Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence. J. Biol. Chem. 1998; 273: 12 415-21.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12415-12421
-
-
Yasuda, M.1
Theodorakis, P.2
Subramanian, T.3
Chinnadurai, G.4
-
67
-
-
0031806909
-
Adenovirus E1B 19,000-molecular-weight protein activates c-Jun N-terminal kinase and c-Jun-mediated transcription
-
67 See RH, Shi Y. Adenovirus E1B 19,000-molecular-weight protein activates c-Jun N-terminal kinase and c-Jun-mediated transcription. Mol. Cell. Biol. 1998; 18: 4012-22.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4012-4022
-
-
See, R.H.1
Shi, Y.2
-
68
-
-
0031974917
-
Sindbis virus induces apoptosis through a caspase-dependent, CrmA-sensitive pathway
-
68 Nava VE, Rosen A, Veliuona MA, Clem RJ, Levine B, Hardwick JM. Sindbis virus induces apoptosis through a caspase-dependent, CrmA-sensitive pathway. J. Virol. 1998; 72: 452-9.
-
(1998)
J. Virol.
, vol.72
, pp. 452-459
-
-
Nava, V.E.1
Rosen, A.2
Veliuona, Ma.3
Clem, R.J.4
Levine, B.5
Hardwick, J.M.6
-
69
-
-
0029837991
-
Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV
-
69 Moore PS, Boshoff C, Weiss RA, Chang Y. Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV. Science 1996; 274: 1739-44.
-
(1996)
Science
, vol.274
, pp. 1739-1744
-
-
Moore, P.S.1
Boshoff, C.2
Weiss, R.A.3
Chang, Y.4
-
70
-
-
0001651446
-
Cyclin encoded by KS herpesvirus
-
70 Chang Y, Moore PS, Talbot SJ et al. Cyclin encoded by KS herpesvirus (Letter). Nature 1996; 382: 410.
-
(1996)
Nature
, vol.382
, pp. 410
-
-
Chang, Y.1
Moore, P.S.2
Talbot, S.J.3
-
71
-
-
0031746909
-
Antiapoptotic activity of the herpesvirus saimiri-encoded Bcl-2 homolog: Stabilization of mitochondria and inhibition of caspase-3-like activity
-
71 Derfuss T, Fickenscher H, Kraft MS et al. Antiapoptotic activity of the herpesvirus saimiri-encoded Bcl-2 homolog: Stabilization of mitochondria and inhibition of caspase-3-like activity. J. Virol. 1998; 72: 5897-904.
-
(1998)
J. Virol.
, vol.72
, pp. 5897-5904
-
-
Derfuss, T.1
Fickenscher, H.2
Kraft, M.S.3
-
72
-
-
0023820255
-
Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation
-
72 Jenne DE, Tschopp J. Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation. Immunol. Rev. 1988; 103: 53-71.
-
(1988)
Immunol. Rev.
, vol.103
, pp. 53-71
-
-
Jenne, D.E.1
Tschopp, J.2
-
73
-
-
0025230476
-
Perforin-mediated target cell lysis by cytolytic T lymphocytes
-
73 Tschopp J, Nabholz M. Perforin-mediated target cell lysis by cytolytic T lymphocytes. Annu. Rev. Immunol. 1990; 8: 279-302.
-
(1990)
Annu. Rev. Immunol.
, vol.8
, pp. 279-302
-
-
Tschopp, J.1
Nabholz, M.2
-
74
-
-
0026659467
-
Perforin: Structure, function, and regulation
-
74 Podack ER. Perforin: Structure, function, and regulation. Curr. Top. Microbiol. Immunol. 1992; 178: 175-84.
-
(1992)
Curr. Top. Microbiol. Immunol.
, vol.178
, pp. 175-184
-
-
Podack, E.R.1
-
75
-
-
0026662493
-
Role of perforin in lymphocyte-mediated cytolysis
-
75 Yagita H, Nakata M, Kawasaki A, Shinkai Y, Okumura K. Role of perforin in lymphocyte-mediated cytolysis. Adv. Immunol. 1992; 51: 215-42.
-
(1992)
Adv. Immunol.
, vol.51
, pp. 215-242
-
-
Yagita, H.1
Nakata, M.2
Kawasaki, A.3
Shinkai, Y.4
Okumura, K.5
-
76
-
-
0024416820
-
Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A
-
76 Hayes MP, Berrebi GA, Henkart PA. Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A. J. Exp. Med. 1989; 170: 933-46.
-
(1989)
J. Exp. Med.
, vol.170
, pp. 933-946
-
-
Hayes, M.P.1
Berrebi, G.A.2
Henkart, P.A.3
-
77
-
-
0026532606
-
A natural killer cell granule protein that induces DNA fragmentation and apoptosis
-
77 Shi L, Kraut RP, Aebersold R, Greenberg AH. A natural killer cell granule protein that induces DNA fragmentation and apoptosis. J. Exp. Med. 1992; 175: 553-66.
-
(1992)
J. Exp. Med.
, vol.175
, pp. 553-566
-
-
Shi, L.1
Kraut, R.P.2
Aebersold, R.3
Greenberg, A.H.4
-
78
-
-
0026474805
-
Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions
-
78 Shi L, Kam CM, Powers JC, Aebersold R, Greenberg AH. Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions. J Exp. Med. 1992; 176: 1521-9.
-
(1992)
J Exp. Med.
, vol.176
, pp. 1521-1529
-
-
Shi, L.1
Kam, C.M.2
Powers, J.C.3
Aebersold, R.4
Greenberg, A.H.5
-
80
-
-
0023813169
-
Structure and function of human perform
-
80 Lichtenheld MG, Olsen KJ, Lu P et al. Structure and function of human perform. Nature 1988; 335: 448-51.
-
(1988)
Nature
, vol.335
, pp. 448-451
-
-
Lichtenheld, M.G.1
Olsen, K.J.2
Lu, P.3
-
81
-
-
0023234949
-
The isolation and sequence of a novel gene from a human functional T cell line
-
81 Jongstra J, Schall TJ, Dyer BJ et al. The isolation and sequence of a novel gene from a human functional T cell line. J. Exp. Med. 1987; 165: 601-14.
-
(1987)
J. Exp. Med.
, vol.165
, pp. 601-614
-
-
Jongstra, J.1
Schall, T.J.2
Dyer, B.J.3
-
82
-
-
0020491521
-
Circular polymerization of the ninth component of complement. Ring closure of the tubular complex confers resistance to detergent dissociation and to proteolytic degradation
-
82 Podack ER, Tschopp J. Circular polymerization of the ninth component of complement. Ring closure of the tubular complex confers resistance to detergent dissociation and to proteolytic degradation. J. Biol. Chem. 1982; 257: 15204-12.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 15204-15212
-
-
Podack, E.R.1
Tschopp, J.2
-
83
-
-
0023918720
-
Structure and differential mechanisms of regulation of expression of a serine esterase gene in activated human T lymphocytes
-
83 Caputo A, Fahey D, Lloyd C, Vozab R, McCairns E, Rowe PB. Structure and differential mechanisms of regulation of expression of a serine esterase gene in activated human T lymphocytes. J. Biol. Chem. 1988; 263: 6363-9.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 6363-6369
-
-
Caputo, A.1
Fahey, D.2
Lloyd, C.3
Vozab, R.4
McCairns, E.5
Rowe, P.B.6
-
84
-
-
0025082668
-
Nucleotide sequence and genomic organization of a human T lymphocyte serine protease gene
-
84 Caputo A, Sauer DE, Rowe PB. Nucleotide sequence and genomic organization of a human T lymphocyte serine protease gene. J Immunol. 1990; 145: 737-44.
-
(1990)
J Immunol.
, vol.145
, pp. 737-744
-
-
Caputo, A.1
Sauer, D.E.2
Rowe, P.B.3
-
85
-
-
0022430248
-
Specific release of proteoglycans from human natural killer cells during target lysis
-
85 Schmidt RE, MacDermott RP, Bartley G et al. Specific release of proteoglycans from human natural killer cells during target lysis. Nature 1985; 318: 289-91.
-
(1985)
Nature
, vol.318
, pp. 289-291
-
-
Schmidt, R.E.1
MacDermott, R.P.2
Bartley, G.3
-
86
-
-
0023688825
-
Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes
-
86 Trapani JA, Klein JL, White PC, Dupont B. Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes. Proc. Natl Acad. Sci. USA 1988; 85: 6924-8.
-
(1988)
Proc. Natl Acad. Sci. USA
, vol.85
, pp. 6924-6928
-
-
Trapani, J.A.1
Klein, J.L.2
White, P.C.3
Dupont, B.4
-
87
-
-
0025249843
-
Cloning of a gene that encodes a new member of the human cytotoxic cell protease family
-
87 Meier M, Kwong PC, Fregeau CJ et al. Cloning of a gene that encodes a new member of the human cytotoxic cell protease family. Biochemistry 1990; 29: 4042-9.
-
(1990)
Biochemistry
, vol.29
, pp. 4042-4049
-
-
Meier, M.1
Kwong, P.C.2
Fregeau, C.J.3
-
88
-
-
0025338632
-
Characterization of a novel, human cytotoxic lymphocyte-specific serine protease cDNA clone (CSP-C)
-
88 Klein JL, Selvakumar A, Trapani JA, Dupont B. Characterization of a novel, human cytotoxic lymphocyte-specific serine protease cDNA clone (CSP-C). Tissue Antigens 1990; 35: 220-8.
-
(1990)
Tissue Antigens
, vol.35
, pp. 220-228
-
-
Klein, J.L.1
Selvakumar, A.2
Trapani, J.A.3
Dupont, B.4
-
89
-
-
0026032178
-
Structure and evolutionary origin of the human granzyme H gene
-
89 Haddad P, Jenne D, Tschopp J, Clement MV, Mathieu-Mahul D, Sasportes M. Structure and evolutionary origin of the human granzyme H gene. Int. Immunol. 1991; 3: 57-66.
-
(1991)
Int. Immunol.
, vol.3
, pp. 57-66
-
-
Haddad, P.1
Jenne, D.2
Tschopp, J.3
Clement, M.V.4
Mathieu-Mahul, D.5
Sasportes, M.6
-
90
-
-
0027432306
-
Met-ase: Cloning and distinct chromosomal location of a serine protease preferentially expressed in human natural killer cells
-
90 Smyth MJ, Sayers TJ, Wiltrout T, Powers JC, Trapani JA. Met-ase: Cloning and distinct chromosomal location of a serine protease preferentially expressed in human natural killer cells. J. Immunol. 1993; 151: 6195-205.
-
(1993)
J. Immunol.
, vol.151
, pp. 6195-6205
-
-
Smyth, M.J.1
Sayers, T.J.2
Wiltrout, T.3
Powers, J.C.4
Trapani, J.A.5
-
91
-
-
0023687512
-
Characterization of three serine esterascs isolated from human IL-2 activated killer cells
-
91 Hameed A, Lowrey DM, Lichtenheld M, Podack ER. Characterization of three serine esterascs isolated from human IL-2 activated killer cells. J. Immunol. 1988; 141: 3142-7.
-
(1988)
J. Immunol.
, vol.141
, pp. 3142-3147
-
-
Hameed, A.1
Lowrey, D.M.2
Lichtenheld, M.3
Podack, E.R.4
-
92
-
-
0025597939
-
The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments
-
92 Burkhardt JK, Hester S, Lapham CK, Argon Y. The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments. J. Cell Biol. 1990; 111: 2327-40.
-
(1990)
J. Cell Biol.
, vol.111
, pp. 2327-2340
-
-
Burkhardt, J.K.1
Hester, S.2
Lapham, C.K.3
Argon, Y.4
-
93
-
-
0020309431
-
Electron microscopic study of natural killer cell-tumor cell conjugates
-
93 Frey T, Petty HR, McConnell HM. Electron microscopic study of natural killer cell-tumor cell conjugates. Proc. Natl Acad. Sci. USA 1982; 79: 5317-21.
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, pp. 5317-5321
-
-
Frey, T.1
Petty, H.R.2
McConnell, H.M.3
-
94
-
-
0027260897
-
Regulation by glutathione of the activation and differentiation of IL-4-dependent activated killer cells
-
94 Hargrove ME, Wang J, Ting CC. Regulation by glutathione of the activation and differentiation of IL-4-dependent activated killer cells. Cell. Immunol. 1993; 149: 433-43.
-
(1993)
Cell. Immunol.
, vol.149
, pp. 433-443
-
-
Hargrove, M.E.1
Wang, J.2
Ting, C.C.3
-
95
-
-
0021601269
-
Beta-glucuronidase activity in human T and B lymphocytes and the Tmu and T gamma subpopulations
-
95 Orye E, Plum J, De Smedt M. Beta-glucuronidase activity in human T and B lymphocytes and the Tmu and T gamma subpopulations. Histochemistry 1984; 81: 287-90.
-
(1984)
Histochemistry
, vol.81
, pp. 287-290
-
-
Orye, E.1
Plum, J.2
De Smedt, M.3
-
96
-
-
0027452741
-
Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor
-
96 Griffiths GM, Isaaz S. Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor. J. Cell Biol. 1993; 120: 885-96.
-
(1993)
J. Cell Biol.
, vol.120
, pp. 885-896
-
-
Griffiths, G.M.1
Isaaz, S.2
-
97
-
-
0025905925
-
Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes
-
97 Peters PJ, Borst J, Oorschot V et al. Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes. J. Exp. Med. 1991; 173: 1099-109.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 1099-1109
-
-
Peters, P.J.1
Borst, J.2
Oorschot, V.3
-
98
-
-
0026782109
-
Calreticulin in T-lymphocytes. Identification of calreticulin in T-lymphocytes and demonstration that activation of T cells correlates with increased levels of calreticulin mRNA and protein
-
98 Burns K, Helgason CD, Bleackley RC, Michalak M. Calreticulin in T-lymphocytes. Identification of calreticulin in T-lymphocytes and demonstration that activation of T cells correlates with increased levels of calreticulin mRNA and protein. J. Biol. Chem. 1992; 267: 19039-42.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 19039-19042
-
-
Burns, K.1
Helgason, C.D.2
Bleackley, R.C.3
Michalak, M.4
-
99
-
-
0023260793
-
Co-sedimentation of chondroitin sulfate A glycosaminoglycans and proteoglycans with the cytolytic secretory granules of rat large granular lymphocyte (LGL) tumor cells, and identification of a mRNA in normal and transformed LGL that encodes proteoglycans
-
99 Stevens RL, Otsu K, Weis JH et al. Co-sedimentation of chondroitin sulfate A glycosaminoglycans and proteoglycans with the cytolytic secretory granules of rat large granular lymphocyte (LGL) tumor cells, and identification of a mRNA in normal and transformed LGL that encodes proteoglycans. J. Immunol. 1987; 139: 863-8.
-
(1987)
J. Immunol.
, vol.139
, pp. 863-868
-
-
Stevens, R.L.1
Otsu, K.2
Weis, J.H.3
-
100
-
-
0027518670
-
Generation of active myeloid and lymphoid granule serine proteases requires processing by the granule thiol protease dipeptidyl peptidase I
-
100 McGuire MJ, Lipsky PE, Thiele DL. Generation of active myeloid and lymphoid granule serine proteases requires processing by the granule thiol protease dipeptidyl peptidase I. J. Biol. Chem. 1993; 268: 2458-67.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 2458-2467
-
-
McGuire, M.J.1
Lipsky, P.E.2
Thiele, D.L.3
-
101
-
-
0029871982
-
Leukophysin: An RNA helicase A-related molecule identified in cytotoxic T cell granules and vesicles
-
101 Abdelhaleem MM, Hameed S, Klassen D, Greenberg AH. Leukophysin: An RNA helicase A-related molecule identified in cytotoxic T cell granules and vesicles. J. Immunol. 1996; 156: 2026-35.
-
(1996)
J. Immunol.
, vol.156
, pp. 2026-2035
-
-
Abdelhaleem, M.M.1
Hameed, S.2
Klassen, D.3
Greenberg, A.H.4
-
102
-
-
0023646765
-
Identification, isolation, and characterization of a novel cytotoxin in murine cytolytic lymphocytes
-
102 Liu CC, Steffen M, King F, Young JD. Identification, isolation, and characterization of a novel cytotoxin in murine cytolytic lymphocytes. Cell 1987; 51: 393-403.
-
(1987)
Cell
, vol.51
, pp. 393-403
-
-
Liu, C.C.1
Steffen, M.2
King, F.3
Young, J.D.4
-
103
-
-
0025015146
-
A monoclonal antibody reactive with a 15-kDa cytoplasmic granule-associated protein defines a subpopulation of CD8+ T lymphocytes
-
103 Anderson P, Nagler-Anderson C, O'Brien C et al. A monoclonal antibody reactive with a 15-kDa cytoplasmic granule-associated protein defines a subpopulation of CD8+ T lymphocytes. J. Immunol. 1990; 144: 574-82.
-
(1990)
J. Immunol.
, vol.144
, pp. 574-582
-
-
Anderson, P.1
Nagler-Anderson, C.2
O'Brien, C.3
-
104
-
-
0022362235
-
The reorientation of the Golgi apparatus and the microtubule-organizing center in the cytotoxic effector cell is a prerequisite in the lysis of bound target cells
-
104 Kupfer A, Dennert G, Singer SJ. The reorientation of the Golgi apparatus and the microtubule-organizing center in the cytotoxic effector cell is a prerequisite in the lysis of bound target cells. J. Mol. Cell. Immunol. 1985; 2: 37-49.
-
(1985)
J. Mol. Cell. Immunol.
, vol.2
, pp. 37-49
-
-
Kupfer, A.1
Dennert, G.2
Singer, S.J.3
-
105
-
-
0022653477
-
Reorientation and fusion of cytotoxic T lymphocyte granules after interaction with target cells as determined by high resolution cinemicrography
-
105 Yannelli JR, Sullivan JA, Mandell GL, Engelhard VH. Reorientation and fusion of cytotoxic T lymphocyte granules after interaction with target cells as determined by high resolution cinemicrography. J. Immunol. 1986; 136: 377-82.
-
(1986)
J. Immunol.
, vol.136
, pp. 377-382
-
-
Yannelli, J.R.1
Sullivan, J.A.2
Mandell, G.L.3
Engelhard, V.H.4
-
106
-
-
0023204627
-
Inhibition of the lytic activity of perforin (cytolysin) and of late complement components by proteoglycans
-
106 Tschopp J, Masson D. Inhibition of the lytic activity of perforin (cytolysin) and of late complement components by proteoglycans. Mol. Immunol. 1987; 24: 907-13.
-
(1987)
Mol. Immunol.
, vol.24
, pp. 907-913
-
-
Tschopp, J.1
Masson, D.2
-
107
-
-
0022308091
-
Mechanism of lymphocyte-mediated cytotoxicity
-
107 Henkart PA. Mechanism of lymphocyte-mediated cytotoxicity. Annu. Rev. Immunol. 1985; 3: 31-58.
-
(1985)
Annu. Rev. Immunol.
, vol.3
, pp. 31-58
-
-
Henkart, P.A.1
-
108
-
-
0022500783
-
Cell-mediated killing: A common mechanism?
-
108 Young JD, Cohn ZA. Cell-mediated killing: A common mechanism? Cell 1986; 46: 641-2.
-
(1986)
Cell
, vol.46
, pp. 641-642
-
-
Young, J.D.1
Cohn, Z.A.2
-
109
-
-
0022253052
-
Isolation of a lytic, pore-forming protein (perforin) from cytolytic T-lymphocytes
-
109 Masson D, Tschopp J. Isolation of a lytic, pore-forming protein (perforin) from cytolytic T-lymphocytes. J. Biol. Chem. 1985; 260: 9069-72.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 9069-9072
-
-
Masson, D.1
Tschopp, J.2
-
110
-
-
0025950813
-
Debate: The mechanism of lymphocyte-mediated killing. Lymphocyte-triggered internal target disintegration
-
110 Berke G. Debate: The mechanism of lymphocyte-mediated killing. Lymphocyte-triggered internal target disintegration. Immunol. Today 1991; 12: 396-9, 402.
-
(1991)
Immunol. Today
, vol.12
, pp. 396-399
-
-
Berke, G.1
-
111
-
-
0001041396
-
Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules
-
111 Podack ER, Young JD, Cohn ZA. Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules. Proc. Natl Acad. Sci. USA 1985; 82: 8629-33.
-
(1985)
Proc. Natl Acad. Sci. USA
, vol.82
, pp. 8629-8633
-
-
Podack, E.R.1
Young, J.D.2
Cohn, Z.A.3
-
112
-
-
0028219791
-
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
-
112 Kagi D, Ledermann B, Burki K et al. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 1994; 369: 31-7.
-
(1994)
Nature
, vol.369
, pp. 31-37
-
-
Kagi, D.1
Ledermann, B.2
Burki, K.3
-
113
-
-
0027946007
-
A null mutation in the perforin gene impairs cytolytic T lymphocyte-and natural killer cell-mediated cytotoxicity
-
113 Lowin B, Beermann F, Schmidt A, Tschopp J. A null mutation in the perforin gene impairs cytolytic T lymphocyte-and natural killer cell-mediated cytotoxicity. Proc. Natl Acad. Sci. USA 1994; 91: 11 571-5.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 11571-11575
-
-
Lowin, B.1
Beermann, F.2
Schmidt, A.3
Tschopp, J.4
-
114
-
-
0028608085
-
CD8+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity
-
114 Kagi D, Ledermann B, Burki K, Hengartner H, Zinkernagel RM. CD8+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity. Eur. J. Immunol. 1994; 24: 3068-72.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 3068-3072
-
-
Kagi, D.1
Ledermann, B.2
Burki, K.3
Hengartner, H.4
Zinkernagel, R.M.5
-
116
-
-
0028486130
-
Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes
-
116 Kojima H, Shinohara N, Hanaoka S et al. Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes. Immunity 1994; 1: 357-64.
-
(1994)
Immunity
, vol.1
, pp. 357-364
-
-
Kojima, H.1
Shinohara, N.2
Hanaoka, S.3
-
117
-
-
0029804782
-
Decreased tumor surveillance in perforin-deficient mice
-
117 van den Broek ME, Kagi D, Ossendorp F et al. Decreased tumor surveillance in perforin-deficient mice. J. Exp. Med. 1996; 184: 1781-90.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1781-1790
-
-
Broek, M.E.1
Kagi, D.2
Ossendorp, F.3
-
118
-
-
0029914331
-
Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo
-
118 Kagi D, Ledermann B, Burki K, Zinkernagel RM, Hengartner H. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu. Rev. Immunol. 1996; 14: 207-32.
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 207-232
-
-
Kagi, D.1
Ledermann, B.2
Burki, K.3
Zinkernagel, R.M.4
Hengartner, H.5
-
119
-
-
0026707567
-
Perforin and its role in T lymphocyte-mediated cytolysis
-
119 Lowin B, Krahenbuhl O, Muller C, Dupuis M, Tschopp J. Perforin and its role in T lymphocyte-mediated cytolysis. Experientia 1992; 48: 911-20.
-
(1992)
Experientia
, vol.48
, pp. 911-920
-
-
Lowin, B.1
Krahenbuhl, O.2
Muller, C.3
Dupuis, M.4
Tschopp, J.5
-
120
-
-
0028265815
-
Cytotoxic lymphocyte granzymes trigger a target cell internal disintegration pathway leading to cytolysis and DNA breakdown
-
120 Nakajima H, Henkart PA. Cytotoxic lymphocyte granzymes trigger a target cell internal disintegration pathway leading to cytolysis and DNA breakdown. J. Immunol. 1994; 152: 1057-63.
-
(1994)
J. Immunol.
, vol.152
, pp. 1057-1063
-
-
Nakajima, H.1
Henkart, P.A.2
-
121
-
-
0024430418
-
Purified perforin induces target cell lysis but not DNA fragmentation
-
121 Duke RC, Persechini PM, Chang S, Liu CC, Cohen JJ, Young JD. Purified perforin induces target cell lysis but not DNA fragmentation. J. Exp. Med. 1989; 170: 1451-6.
-
(1989)
J. Exp. Med.
, vol.170
, pp. 1451-1456
-
-
Duke, R.C.1
Persechini, P.M.2
Chang, S.3
Liu, C.C.4
Cohen, J.J.5
Young, J.D.6
-
122
-
-
0023841072
-
Calcium ion concentrations and DNA fragmentation in target cell destruction by murine cloned cytotoxic T lymphocytes
-
122 Allbritton NL, Verret CR, Wolley RC, Eisen HN. Calcium ion concentrations and DNA fragmentation in target cell destruction by murine cloned cytotoxic T lymphocytes. J. Exp. Med. 1988; 167: 514-27.
-
(1988)
J. Exp. Med.
, vol.167
, pp. 514-527
-
-
Allbritton, N.L.1
Verret, C.R.2
Wolley, R.C.3
Eisen, H.N.4
-
123
-
-
0021183979
-
Cytolytic activity of purified cytoplasmic granules from cytotoxic rat large granular lymphocyte tumors
-
123 Henkart PA, Millard PJ, Reynolds CW, Henkart MP Cytolytic activity of purified cytoplasmic granules from cytotoxic rat large granular lymphocyte tumors. J. Exp. Med. 1984; 160: 75-93.
-
(1984)
J. Exp. Med.
, vol.160
, pp. 75-93
-
-
Henkart, P.A.1
Millard, P.J.2
Reynolds, C.W.3
Henkart, M.P.4
-
124
-
-
0023905965
-
The role of cytoplasmic granules in lymphocyte cytotoxicity
-
124 Henkart P, Yue CC. The role of cytoplasmic granules in lymphocyte cytotoxicity. Prog. Allergy 1988; 40: 82-110.
-
(1988)
Prog. Allergy
, vol.40
, pp. 82-110
-
-
Henkart, P.1
Yue, C.C.2
-
125
-
-
0021270576
-
Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization
-
125 Podack ER, Konigsberg PJ. Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization. J. Exp. Med. 1984; 160: 695-710.
-
(1984)
J. Exp. Med.
, vol.160
, pp. 695-710
-
-
Podack, E.R.1
Konigsberg, P.J.2
-
126
-
-
0013606585
-
Lymphocyte-mediated cytolysis. Role of granule mediators
-
Harris JR (ed.). USA: Plenum Publishing Corporation
-
126 Young JD, Kwon BS, Trapani JA, Liu C, Young LHY. Lymphocyte-mediated cytolysis. Role of granule mediators. In: Harris JR (ed.) Blood Cell Biochemistry, vol. 3. USA: Plenum Publishing Corporation, 1991; 143-62.
-
(1991)
Blood Cell Biochemistry
, vol.3
, pp. 143-162
-
-
Young, J.D.1
Kwon, B.S.2
Trapani, J.A.3
Liu, C.4
Young, L.H.Y.5
-
127
-
-
0025774123
-
The function of lymphocyte proteases. Inhibition and restoration of granule-mediated lysis with isocoumarin serine protease inhibitors
-
127 Hudig D, Allison NJ, Pickett TM, Winkler U, Kam CM, Powers JC. The function of lymphocyte proteases. Inhibition and restoration of granule-mediated lysis with isocoumarin serine protease inhibitors. J. Immunol. 1991; 147: 1360-8.
-
(1991)
J. Immunol.
, vol.147
, pp. 1360-1368
-
-
Hudig, D.1
Allison, N.J.2
Pickett, T.M.3
Winkler, U.4
Kam, C.M.5
Powers, J.C.6
-
128
-
-
0018825585
-
Effects of N-alpha-tosyl-L-lysyl-chloromethylketone on the activity of cytotoxic T lymphocytes
-
128 Chang TW, Eisen HN. Effects of N-alpha-tosyl-L-lysyl-chloromethylketone on the activity of cytotoxic T lymphocytes. J. Immunol. 1980; 124: 1028-33.
-
(1980)
J. Immunol.
, vol.124
, pp. 1028-1033
-
-
Chang, T.W.1
Eisen, H.N.2
-
129
-
-
0028113356
-
Chymase-directed serine protease inhibitor that reacts with a single 30-kDa granzyme and blocks NK-mediated cytotoxicity
-
129 Woodard SL, Jackson DS, Abuelyaman AS, Powers JC, Winkler U, Hudig D. Chymase-directed serine protease inhibitor that reacts with a single 30-kDa granzyme and blocks NK-mediated cytotoxicity. J. Immunol. 1994; 153: 5016-25.
-
(1994)
J. Immunol.
, vol.153
, pp. 5016-5025
-
-
Woodard, S.L.1
Jackson, D.S.2
Abuelyaman, A.S.3
Powers, J.C.4
Winkler, U.5
Hudig, D.6
-
130
-
-
0027950774
-
Hypothesis: Cytotoxic lymphocyte granule serine proteases activate target cell endonucleases to trigger apoptosis
-
130 Smyth MJ, Browne KA, Thia KY, Apostolidis VA, Kershaw MH, Trapani JA. Hypothesis: Cytotoxic lymphocyte granule serine proteases activate target cell endonucleases to trigger apoptosis. Clin. Exp. Pharmacol. Physiol. 1994; 21: 67-70.
-
(1994)
Clin. Exp. Pharmacol. Physiol.
, vol.21
, pp. 67-70
-
-
Smyth, M.J.1
Browne, K.A.2
Thia, K.Y.3
Apostolidis, V.A.4
Kershaw, M.H.5
Trapani, J.A.6
-
131
-
-
0026753388
-
Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A
-
131 Shiver JW, Su L, Henkart PA. Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A. Cell 1992; 71: 315-22.
-
(1992)
Cell
, vol.71
, pp. 315-322
-
-
Shiver, J.W.1
Su, L.2
Henkart, P.A.3
-
132
-
-
0028938366
-
The target cell nucleus is not required for cell-mediated granzyme-or Fas-based cytotoxicity
-
132 Nakajima H, Golstein P, Henkart PA. The target cell nucleus is not required for cell-mediated granzyme-or Fas-based cytotoxicity. J. Exp. Med. 1995; 181: 1905-9.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1905-1909
-
-
Nakajima, H.1
Golstein, P.2
Henkart, P.A.3
-
133
-
-
0025973806
-
A noncytotoxic mast cell tumor line exhibits potent IgE-dependent cytotoxicity after transfection with the cytolysin/perforin gene
-
133 Shiver JW, Henkart PA. A noncytotoxic mast cell tumor line exhibits potent IgE-dependent cytotoxicity after transfection with the cytolysin/perforin gene. Cell 1991; 64: 1175-81.
-
(1991)
Cell
, vol.64
, pp. 1175-1181
-
-
Shiver, J.W.1
Henkart, P.A.2
-
134
-
-
0030892138
-
Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization
-
134 Shi L, Mai S, Israels S, Browne K, Trapani JA, Greenberg AH. Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization. J. Exp. Med. 1997; 185: 855-66.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 855-866
-
-
Shi, L.1
Mai, S.2
Israels, S.3
Browne, K.4
Trapani, J.A.5
Greenberg, A.H.6
-
135
-
-
0029844220
-
Nuclear transport of granzyme B (fragmentin-2). Dependence of perforin in vivo and cytosolic factors in vitro
-
135 Jans DA, Jans P, Briggs LJ, Sutton V, Trapani JA. Nuclear transport of granzyme B (fragmentin-2). Dependence of perforin in vivo and cytosolic factors in vitro. J. Biol. Chem. 1996; 271: 30 781-9.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30781-30789
-
-
Jans, D.A.1
Jans, P.2
Briggs, L.J.3
Sutton, V.4
Trapani, J.A.5
-
136
-
-
0032561352
-
Efficient nuclear targetting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent
-
136 Trapani JA, Jans DA, Browne KA, Smyth MJ, Jans PJ, Sutton VR. Efficient nuclear targetting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent. J. Biol. Chem. 1998; 273: 27 934-8.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27934-27938
-
-
Trapani, J.A.1
Jans, D.A.2
Browne, K.A.3
Smyth, M.J.4
Jans, P.J.5
Sutton, V.R.6
-
137
-
-
0031669558
-
Nuclear targeting of the serine protease granzyme A (fragmentin-1)
-
137 Jans DA, Briggs LJ, Jans P et al. Nuclear targeting of the serine protease granzyme A (fragmentin-1). J. Cell Sci. 1998; 111: 2645-54.
-
(1998)
J. Cell Sci.
, vol.111
, pp. 2645-2654
-
-
Jans, D.A.1
Briggs, L.J.2
Jans, P.3
-
138
-
-
0344053451
-
In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
-
138 Fernandes-Alnemri T, Armstrong RC, Krebs J et al. In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc. Natl Acad. Sci. USA 1996; 93: 7464-9.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 7464-7469
-
-
Fernandes-Alnemri, T.1
Armstrong, R.C.2
Krebs, J.3
-
139
-
-
8944241298
-
DNA-dependent protein kinase catalytic subunit: A target for an ICE-like protease in apoptosis
-
139 Song Q, Lees-Miller SP, Kumar S et al. DNA-dependent protein kinase catalytic subunit: A target for an ICE-like protease in apoptosis. EMBO J. 1996; 15: 3238-46.
-
(1996)
EMBO J.
, vol.15
, pp. 3238-3246
-
-
Song, Q.1
Lees-Miller, S.P.2
Kumar, S.3
-
140
-
-
0030569503
-
Human perforin: Rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays
-
140 Froelich CJ, Turbov J, Hanna W. Human perforin: Rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays. Biochem. Biophys. Res. Commun. 1996; 229: 44-9.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.229
, pp. 44-49
-
-
Froelich, C.J.1
Turbov, J.2
Hanna, W.3
-
141
-
-
0031952224
-
Lymphocyte granule-mediated apoptosis: Matters of viral mimicry and deadly proteases
-
141 Froelich CJ, Dixit VM, Yang X. Lymphocyte granule-mediated apoptosis: Matters of viral mimicry and deadly proteases. Immunol. Today 1998; 19: 30-6.
-
(1998)
Immunol. Today
, vol.19
, pp. 30-36
-
-
Froelich, C.J.1
Dixit, V.M.2
Yang, X.3
-
143
-
-
0028149332
-
Apoptotic cell death induced by intracellular proteolysis
-
143 Williams MS, Henkart PA. Apoptotic cell death induced by intracellular proteolysis. J. Immunol. 1994; 153: 4247-55.
-
(1994)
J. Immunol.
, vol.153
, pp. 4247-4255
-
-
Williams, M.S.1
Henkart, P.A.2
-
144
-
-
0028287944
-
Granule serine proteases are normal nuclear constituents of natural killer cells
-
144 Trapani JA, Smyth MJ, Apostolidis VA, Dawson M, Browne KA. Granule serine proteases are normal nuclear constituents of natural killer cells. J. Biol. Chem. 1994; 269: 18 359-65.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18359-18365
-
-
Trapani, J.A.1
Smyth, M.J.2
Apostolidis, V.A.3
Dawson, M.4
Browne, K.A.5
-
145
-
-
0024291666
-
Cytotoxic T lymphocyte mediated cytolysis
-
145 Tschopp J, Jongeneel CV. Cytotoxic T lymphocyte mediated cytolysis. Biochemistry 1988; 27: 2641-6.
-
(1988)
Biochemistry
, vol.27
, pp. 2641-2646
-
-
Tschopp, J.1
Jongeneel, C.V.2
-
146
-
-
0028952301
-
Granzymes: Exogenous proteinases that induce target cell apoptosis
-
146 Smyth MJ, Trapani JA. Granzymes: Exogenous proteinases that induce target cell apoptosis. Immunol. Today 1995; 16: 202-6.
-
(1995)
Immunol. Today
, vol.16
, pp. 202-206
-
-
Smyth, M.J.1
Trapani, J.A.2
-
147
-
-
0027169762
-
Activation of recombinant murine cytotoxic cell proteinase-1 requires deletion of an amino-terminal dipeptide
-
147 Caputo A, Garner RS, Winkler U, Hudig D, Bleackley RC. Activation of recombinant murine cytotoxic cell proteinase-1 requires deletion of an amino-terminal dipeptide. J. Biol. Chem. 1993; 268: 17672-5.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 17672-17675
-
-
Caputo, A.1
Garner, R.S.2
Winkler, U.3
Hudig, D.4
Bleackley, R.C.5
-
148
-
-
0023645045
-
A family of serine esterases in lytic granules of cytolytic T lymphocytes
-
148 Masson D, Tschopp J. A family of serine esterases in lytic granules of cytolytic T lymphocytes. Cell 1987; 49: 679-85.
-
(1987)
Cell
, vol.49
, pp. 679-685
-
-
Masson, D.1
Tschopp, J.2
-
150
-
-
0023786907
-
Human cytotoxic lymphocyte tryptase. Its purification from granules and the characterization of inhibitor and substrate specificity
-
150 Poe M, Bennett CD, Biddison WE et al. Human cytotoxic lymphocyte tryptase. Its purification from granules and the characterization of inhibitor and substrate specificity. J. Biol. Chem. 1988; 263: 13215-22.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 13215-13222
-
-
Poe, M.1
Bennett, C.D.2
Biddison, W.E.3
-
151
-
-
0025219649
-
Structural organization of the hCTLA-1 gene encoding human granzyme B
-
151 Haddad P, Clement MV, Bernard O et al. Structural organization of the hCTLA-1 gene encoding human granzyme B. Gene 1990; 87: 265-71.
-
(1990)
Gene
, vol.87
, pp. 265-271
-
-
Haddad, P.1
Clement, M.V.2
Bernard, O.3
-
152
-
-
0025962661
-
Human cytotoxic lymphocyte granzyme B. Its purification from granules and the characterization of substrate and inhibitor specificity
-
152 Poe M, Blake JT, Boulton DA et al. Human cytotoxic lymphocyte granzyme B. Its purification from granules and the characterization of substrate and inhibitor specificity. J. Biol. Chem. 1991; 266: 98-103.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 98-103
-
-
Poe, M.1
Blake, J.T.2
Boulton, D.A.3
-
153
-
-
0025971396
-
Human and murine cytotoxic T lymphocyte serine proteases: Subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins
-
153 Odake S, Kam CM, Narasimhan L et al. Human and murine cytotoxic T lymphocyte serine proteases: Subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins. Biochemistry 1991; 30: 2217-27.
-
(1991)
Biochemistry
, vol.30
, pp. 2217-2227
-
-
Odake, S.1
Kam, C.M.2
Narasimhan, L.3
-
154
-
-
0029937520
-
Cloning and expression of a second human natural killer cell granule tryptase, HNK-Tryp-2/granzyme 3
-
154 Sayers TJ, Lloyd AR, McVicar DW et al. Cloning and expression of a second human natural killer cell granule tryptase, HNK-Tryp-2/granzyme 3. J. Leukoc. Biol. 1996; 59: 763-8.
-
(1996)
J. Leukoc. Biol.
, vol.59
, pp. 763-768
-
-
Sayers, T.J.1
Lloyd, A.R.2
McVicar, D.W.3
-
155
-
-
0026448863
-
Purification and cloning of a novel serine protease, RNK-Met-1, from the granules of a rat natural killer cell leukemia
-
155 Smyth MJ, Wiltrout T, Trapani JA et al. Purification and cloning of a novel serine protease, RNK-Met-1, from the granules of a rat natural killer cell leukemia. J. Biol. Chem. 1992; 267: 24 418-25.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 24418-24425
-
-
Smyth, M.J.1
Wiltrout, T.2
Trapani, J.A.3
-
156
-
-
0029888610
-
A novel substrate-binding pocket interaction restricts the specificity of the human NK cell-specific serine protease, Met-ase-1
-
156 Smyth MJ, O'Connor MD, Trapani JA, Kershaw MH, Brinkworth RI. A novel substrate-binding pocket interaction restricts the specificity of the human NK cell-specific serine protease, Met-ase-1. J. Immunol. 1996; 156: 4174-81.
-
(1996)
J. Immunol.
, vol.156
, pp. 4174-4181
-
-
Smyth, M.J.1
O'Connor, M.D.2
Trapani, J.A.3
Kershaw, M.H.4
Brinkworth, R.I.5
-
157
-
-
0028258577
-
Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
-
157 Heusel JW, Wesselschmidt RL, Shresta S, Russell JH, Ley TJ. Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 1994; 76: 977-87.
-
(1994)
Cell
, vol.76
, pp. 977-987
-
-
Heusel, J.W.1
Wesselschmidt, R.L.2
Shresta, S.3
Russell, J.H.4
Ley, T.J.5
-
158
-
-
0029083438
-
Granzyme A-deficient mice retain potent cell-mediated cytotoxicity
-
158 Ebnet K, Hausmann M, Lehmann-Grube F et al. Granzyme A-deficient mice retain potent cell-mediated cytotoxicity. EMBO J. 1995; 14: 4230-9.
-
(1995)
EMBO J.
, vol.14
, pp. 4230-4239
-
-
Ebnet, K.1
Hausmann, M.2
Lehmann-Grube, F.3
-
159
-
-
0023132276
-
Cloned cytolytic T-effector cells and their malignant variants produce an extracellular matrix degrading trypsin-like serine proteinase
-
159 Simon MM, Simon HG, Fruth U, Epplen J, Muller-Hermelink HK, Kramer MD. Cloned cytolytic T-effector cells and their malignant variants produce an extracellular matrix degrading trypsin-like serine proteinase. Immunology 1987; 60: 219-30.
-
(1987)
Immunology
, vol.60
, pp. 219-230
-
-
Simon, M.M.1
Simon, H.G.2
Fruth, U.3
Epplen, J.4
Muller-Hermelink, H.K.5
Kramer, M.D.6
-
161
-
-
0030014911
-
Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia
-
161 Mullbacher A, Ebnet K, Blanden RV et al. Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia. Proc. Natl Acad. Sci. USA 1996; 93; 5783-7.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 5783-5787
-
-
Mullbacher, A.1
Ebnet, K.2
Blanden, R.V.3
-
162
-
-
0025805998
-
Mouse T-cell associated serine proteinase 1 degrades collagen type IV. A structural basis for the migration of lymphocytes through vascular basement membranes
-
162 Simon MM, Kramer MD, Prester M, Gay S. Mouse T-cell associated serine proteinase 1 degrades collagen type IV. A structural basis for the migration of lymphocytes through vascular basement membranes. Immunology 1991; 73: 117-19.
-
(1991)
Immunology
, vol.73
, pp. 117-119
-
-
Simon, M.M.1
Kramer, M.D.2
Prester, M.3
Gay, S.4
-
163
-
-
0025128888
-
Activation of pro-urokinase by the human T cell-associated serine proteinase HuTSP-1
-
163 Brunner G, Simon MM, Kramer MD. Activation of pro-urokinase by the human T cell-associated serine proteinase HuTSP-1. FEBS Lett. 1990; 260: 141-4.
-
(1990)
FEBS Lett.
, vol.260
, pp. 141-144
-
-
Brunner, G.1
Simon, M.M.2
Kramer, M.D.3
-
164
-
-
0022962214
-
Purification and characterization of a T cell specific serine proteinase (TSP-1) from cloned cytolytic T lymphocytes
-
164 Simon MM, Hoschutzky H, Fruth U, Simon HG, Kramer MD. Purification and characterization of a T cell specific serine proteinase (TSP-1) from cloned cytolytic T lymphocytes. EMBO J. 1986; 5: 3267-74.
-
(1986)
EMBO J.
, vol.5
, pp. 3267-3274
-
-
Simon, M.M.1
Hoschutzky, H.2
Fruth, U.3
Simon, H.G.4
Kramer, M.D.5
-
165
-
-
0025176652
-
Expression of genes encoding cytotoxic cell-associated serine proteases in thymocytes
-
165 Held W, MacDonald HR, Mueller C. Expression of genes encoding cytotoxic cell-associated serine proteases in thymocytes. Int. Immunol. 1990; 2: 57-62.
-
(1990)
Int. Immunol.
, vol.2
, pp. 57-62
-
-
Held, W.1
Macdonald, H.R.2
Mueller, C.3
-
166
-
-
0027048746
-
Expression and downregulation of cytotoxic cell protease 1 or Granzyme 'B' transcripts during myeloid differentiation of interleukin-3-dependent murine stem cell lines
-
166 Hampson IN, Cross MA, Heyworth CM et al. Expression and downregulation of cytotoxic cell protease 1 or Granzyme 'B' transcripts during myeloid differentiation of interleukin-3-dependent murine stem cell lines. Blood 1992; 80: 3097-105.
-
(1992)
Blood
, vol.80
, pp. 3097-3105
-
-
Hampson, I.N.1
Cross, M.A.2
Heyworth, C.M.3
-
167
-
-
0026353348
-
Granzyme A binding to target cell proteins. Granzyme A binds to and cleaves nucleolin
-
167 Pasternack MS, Bleier KJ, McInerney TN. Granzyme A binding to target cell proteins. Granzyme A binds to and cleaves nucleolin in vitro. J. Biol. Chem. 1991; 266: 14 703-8.
-
(1991)
In Vitro. J. Biol. Chem.
, vol.266
, pp. 14703-14708
-
-
Pasternack, M.S.1
Bleier, K.J.2
McInerney, T.N.3
-
168
-
-
0028059276
-
Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes
-
168 Suidan HS, Bouvier J, Schaerer E, Stone SR, Monard D, Tschopp J. Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes. Proc. Natl Acad. Sci. USA 1994; 91: 8112-16.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 8112-8116
-
-
Suidan, H.S.1
Bouvier, J.2
Schaerer, E.3
Stone, S.R.4
Monard, D.5
Tschopp, J.6
-
169
-
-
0030723209
-
In vitro and ex vivo-derived cytocytic leukocytes from granzymc A × B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells
-
169 Simon MM, Hausmann M, Tran T et al. In vitro and ex vivo-derived cytocytic leukocytes from granzymc A × B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells. J. Exp. Med. 1997; 186: 1781-6.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1781-1786
-
-
Simon, M.M.1
Hausmann, M.2
Tran, T.3
-
170
-
-
0025965846
-
Human lysosomal cathepsin G and granzyme B share a functionally conserved broad spectrum antibacterial peptide
-
170 Shafer WM, Pohl J, Onunka VC, Bangalore N, Travis J. Human lysosomal cathepsin G and granzyme B share a functionally conserved broad spectrum antibacterial peptide. J. Biol. Chem. 1991; 266: 112-16.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 112-116
-
-
Shafer, W.M.1
Pohl, J.2
Onunka, V.C.3
Bangalore, N.4
Travis, J.5
-
171
-
-
0031569218
-
Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins
-
171 Pena SV, Hanson DA, Carr BA, Goralski TJ, Krensky AM. Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins. J. Immunol. 1997; 158: 2680-8.
-
(1997)
J. Immunol.
, vol.158
, pp. 2680-2688
-
-
Pena, S.V.1
Hanson, D.A.2
Carr, B.A.3
Goralski, T.J.4
Krensky, A.M.5
-
172
-
-
0029061894
-
NK-lysin, a novel effector peptide of cytotoxic T and NK cells. Structure and cDNA cloning of the porcine form, induction by interleukin 2, antibacterial and antitumour activity
-
172 Andersson M, Gunne H, Agerberth B et al. NK-lysin, a novel effector peptide of cytotoxic T and NK cells. Structure and cDNA cloning of the porcine form, induction by interleukin 2, antibacterial and antitumour activity. EMBO J. 1995; 14: 1615-25.
-
(1995)
EMBO J.
, vol.14
, pp. 1615-1625
-
-
Andersson, M.1
Gunne, H.2
Agerberth, B.3
-
173
-
-
0029126584
-
Saposin-like proteins (SAPLIP) carry out diverse functions on a common backbone structure
-
173 Munford RS, Sheppard PO, O'Hara PJ. Saposin-like proteins (SAPLIP) carry out diverse functions on a common backbone structure. J. Lipid Res. 1995; 36: 1653-63.
-
(1995)
J. Lipid Res.
, vol.36
, pp. 1653-1663
-
-
Munford, R.S.1
Sheppard, P.O.2
O'Hara, P.J.3
-
174
-
-
0032475823
-
An antimicrobial activity of cytolytic T cells mediated by granulysin
-
174 Stenger S, Hanson DA, Teitelbaum R et al. An antimicrobial activity of cytolytic T cells mediated by granulysin. Science 1998; 282: 121-5.
-
(1998)
Science
, vol.282
, pp. 121-125
-
-
Stenger, S.1
Hanson, D.A.2
Teitelbaum, R.3
-
175
-
-
0013605428
-
Cytotoxic lymphocyte granules: Evolution of vesicles essential for combatting virus infections
-
in press
-
175 Trapani JA, Sutton VR, Smyth MJ. Cytotoxic lymphocyte granules: Evolution of vesicles essential for combatting virus infections. Immunol. Today 1998; in press.
-
(1998)
Immunol. Today
-
-
Trapani, J.A.1
Sutton, V.R.2
Smyth, M.J.3
-
177
-
-
0030599449
-
Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly (ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment
-
177 Froelich CJ, Hanna WL, Poirier GG et al. Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly (ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment. Biochem. Biophys. Res. Commun. 1996; 227: 658-65.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.227
, pp. 658-665
-
-
Froelich, C.J.1
Hanna, W.L.2
Poirier, G.G.3
-
178
-
-
0032055097
-
Granzyme B directly and efficiently cleaves several downstream caspase substrates: Implications for CTL-induced apoptosis
-
178 Andrade F, Roy S, Nicholson D, Thornberry N, Rosen A, Casciola-Rosen L. Granzyme B directly and efficiently cleaves several downstream caspase substrates: Implications for CTL-induced apoptosis. Immunity 1998; 8: 451-60.
-
(1998)
Immunity
, vol.8
, pp. 451-460
-
-
Andrade, F.1
Roy, S.2
Nicholson, D.3
Thornberry, N.4
Rosen, A.5
Casciola-Rosen, L.6
-
179
-
-
0030970351
-
Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity
-
179 Zhou Q, Salvesen GS. Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. Biochem. J. 1997; 324: 361-4.
-
(1997)
Biochem. J.
, vol.324
, pp. 361-364
-
-
Zhou, Q.1
Salvesen, G.S.2
-
180
-
-
0031570536
-
Bcl-2 prevents apoptosis induced by perform and granzyme B, but not that mediated by whole cytotoxic lymphocytes
-
180 Sutton VR, Vaux DL, Trapani JA. Bcl-2 prevents apoptosis induced by perform and granzyme B, but not that mediated by whole cytotoxic lymphocytes. J. Immunol. 1997; 158: 5783-90.
-
(1997)
J. Immunol.
, vol.158
, pp. 5783-5790
-
-
Sutton, V.R.1
Vaux, D.L.2
Trapani, J.A.3
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