메뉴 건너뛰기




Volumn 15, Issue 13, 1996, Pages 3238-3246

DNA-dependent protein kinase catalytic subunit: A target for an ICE-like protease in apoptosis

Author keywords

Apoptosis; DNA dependent protein kinase; Etoposide; ICE like protease; Substrate

Indexed keywords

CYSTEINE PROTEINASE; DNA; DNA BINDING PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN KINASE; PROTEINASE; PROTEINASE INHIBITOR;

EID: 8944241298     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00688.x     Document Type: Article
Times cited : (330)

References (65)
  • 1
    • 0028823417 scopus 로고
    • Lack of correlation between DNA-dependent protein kinase activity and tumor cell radiosensitivity
    • Allalunis-Turner, J.M., Lintott, L.G., Barron, G.M., Day, R.S. and Lees-Miller, S.P. (1995) Lack of correlation between DNA-dependent protein kinase activity and tumor cell radiosensitivity. Cancer Res., 55, 5200-5202.
    • (1995) Cancer Res. , vol.55 , pp. 5200-5202
    • Allalunis-Turner, J.M.1    Lintott, L.G.2    Barron, G.M.3    Day, R.S.4    Lees-Miller, S.P.5
  • 2
    • 0028960511 scopus 로고
    • Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation
    • Blunt, T. et al. (1995) Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell, 80, 813-823.
    • (1995) Cell , vol.80 , pp. 813-823
    • Blunt, T.1
  • 3
    • 0028816760 scopus 로고
    • Complementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double strand break repair mutants by p86 Ku autoantigen
    • Boubnov, N.V. et al. (1995) Complementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double strand break repair mutants by p86 Ku autoantigen. Proc. Natl Acad. Sci. USA, 92, 890-894.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 890-894
    • Boubnov, N.V.1
  • 4
    • 0028788309 scopus 로고
    • Microfilament reorganization during apoptosis: The role of Gas2, a possible substrate for ICE-like proteases
    • Brancolini, C., Benedetti, M. and Schneider, C. (1995) Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE-like proteases. EMBO J., 14, 5179-5190.
    • (1995) EMBO J. , vol.14 , pp. 5179-5190
    • Brancolini, C.1    Benedetti, M.2    Schneider, C.3
  • 5
    • 0025201179 scopus 로고
    • A DNA-activated protein kinase from HeLa cell nuclei
    • Carter, T., Vancurova, I., Sun, I., Lou, W. and DeLeon, S. (1990) A DNA-activated protein kinase from HeLa cell nuclei. Mol. Cell Biol., 10, 6460-6471.
    • (1990) Mol. Cell Biol. , vol.10 , pp. 6460-6471
    • Carter, T.1    Vancurova, I.2    Sun, I.3    Lou, W.4    DeLeon, S.5
  • 6
    • 0027999537 scopus 로고
    • Specific cleavage of the 70 kDa protein component on the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death
    • Casciola-Rosen, L.A., Miller, D.K., Anhalt, G.J. and Rosen, A. (1994) Specific cleavage of the 70 kDa protein component on the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death. J. Biol. Chem., 269, 30757-30760.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30757-30760
    • Casciola-Rosen, L.A.1    Miller, D.K.2    Anhalt, G.J.3    Rosen, A.4
  • 7
    • 0030367822 scopus 로고    scopus 로고
    • Purification and characterization of the DNA-activated protein kinase DNA-PK from human placenta
    • Chan, D.W., Mody, C.H., Ting, N.S.Y. and Lees-Miller, S.P. (1996) Purification and characterization of the DNA-activated protein kinase DNA-PK from human placenta. Biochem. Cell. Biol., 74, 67-73.
    • (1996) Biochem. Cell. Biol. , vol.74 , pp. 67-73
    • Chan, D.W.1    Mody, C.H.2    Ting, N.S.Y.3    Lees-Miller, S.P.4
  • 8
    • 0000102949 scopus 로고
    • Poly(ADP-ribose) polymerase: A molecular nick-sensor
    • de Murcia, G. and de Murcia, J.M. (1994) Poly(ADP-ribose) polymerase: a molecular nick-sensor. Trends Biochem. Sci., 19, 172-176.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 172-176
    • De Murcia, G.1    De Murcia, J.M.2
  • 9
    • 0027048773 scopus 로고
    • Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II
    • Dvir, A., Peterson, S.R., Knuth, M., Lu, H. and Williams, S.D. (1992) Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II. Proc. Natl. Acad. Sci. USA. 89, 11920-11924.
    • (1992) Proc. Natl. Acad. Sci. USA. , vol.89 , pp. 11920-11924
    • Dvir, A.1    Peterson, S.R.2    Knuth, M.3    Lu, H.4    Williams, S.D.5
  • 10
    • 0022497852 scopus 로고
    • Genetic control of programmed cell death in the nematode C. elegans
    • Ellis, H. and Horvitz, H.R. (1986) Genetic control of programmed cell death in the nematode C. elegans. Cell, 44, 817-829.
    • (1986) Cell , vol.44 , pp. 817-829
    • Ellis, H.1    Horvitz, H.R.2
  • 12
    • 13344259987 scopus 로고
    • Proteolytic activation of protein kinase C5 by an ICE-like protease in apoptotic cells
    • Emoto, Y. et al. (1995) Proteolytic activation of protein kinase C5 by an ICE-like protease in apoptotic cells. EMBO J., 14, 6148-6156.
    • (1995) EMBO J. , vol.14 , pp. 6148-6156
    • Emoto, Y.1
  • 13
    • 0029005646 scopus 로고
    • A novel human protease similar to the interleukin-1β converting enzyme induces apoptosis in transfected cells
    • Faucheu, C. et al. (1995) A novel human protease similar to the interleukin-1β converting enzyme induces apoptosis in transfected cells. EMBO J., 14, 1914-1922.
    • (1995) EMBO J. , vol.14 , pp. 1914-1922
    • Faucheu, C.1
  • 14
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1-β-converting enzyme
    • Fernandes-Alnemri, T., Litwack, G. and Alnemri, E.S. (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1-β-converting enzyme. J. Biol. Chem., 269, 30761-30764.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30761-30764
    • Fernandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 15
    • 0029025549 scopus 로고
    • Mch2, a new member of apoptotic Ced-3/Ice cysteine protease gene family
    • Fernandes-Alnemri, T., Litwack, G. and Alnemri, E.S. (1995a) Mch2, a new member of apoptotic Ced-3/Ice cysteine protease gene family. Cancer Res., 55, 2737-2742.
    • (1995) Cancer Res. , vol.55 , pp. 2737-2742
    • Fernandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 16
    • 0028884167 scopus 로고
    • Mch3, a novel human apoptotic cysteine protease highly related to CPP32
    • Fernandes-Alnemri, T. et al. (1995b) Mch3, a novel human apoptotic cysteine protease highly related to CPP32. Cancer Res., 55, 6045-6052.
    • (1995) Cancer Res. , vol.55 , pp. 6045-6052
    • Fernandes-Alnemri, T.1
  • 17
    • 0028303584 scopus 로고
    • Butyrate induced apoptosis in lymphoid cells preceded by transient over-expression of hsp70 mRNA
    • Filippovich, I., Sorokina, N., Khanna, K.K. and Lavin, M.F. (1994) Butyrate induced apoptosis in lymphoid cells preceded by transient over-expression of hsp70 mRNA. Biochem. Biophys. Res. Commun., 198, 257-265.
    • (1994) Biochem. Biophys. Res. Commun. , vol.198 , pp. 257-265
    • Filippovich, I.1    Sorokina, N.2    Khanna, K.K.3    Lavin, M.F.4
  • 18
    • 0027397867 scopus 로고
    • The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
    • Gottlieb, T.M. and Jackson, S.P. (1993) The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell, 72, 131-142.
    • (1993) Cell , vol.72 , pp. 131-142
    • Gottlieb, T.M.1    Jackson, S.P.2
  • 19
    • 0029166984 scopus 로고
    • Cleavage of poly (ADP-ribose) polymerase by interleukin-1β converting enzyme and its homologs TX and NEDD2
    • Gu, Y., Sarnecki, C., Aldape, R.A., Livingston, D.J. and Su, M.S.-S. (1995) Cleavage of poly (ADP-ribose) polymerase by interleukin-1β converting enzyme and its homologs TX and NEDD2. J. Biol Chem., 270, 18715-18718.
    • (1995) J. Biol Chem. , vol.270 , pp. 18715-18718
    • Gu, Y.1    Sarnecki, C.2    Aldape, R.A.3    Livingston, D.J.4    Su, M.S.-S.5
  • 20
    • 0029089618 scopus 로고
    • The mei-41 gene of Drosophila melanogaster is a strucural and functional homolog of the human ataxia-telangiectasia gene
    • Hari, K.L. Santerre, A., Sekelsky, J.J., McKim, K.S., Boyd, J.B. and Hawley, R.S. (1995) The mei-41 gene of Drosophila melanogaster is a strucural and functional homolog of the human ataxia-telangiectasia gene. Cell, 82, 815-821.
    • (1995) Cell , vol.82 , pp. 815-821
    • Hari, K.L.1    Santerre, A.2    Sekelsky, J.J.3    McKim, K.S.4    Boyd, J.B.5    Hawley, R.S.6
  • 21
    • 0029156599 scopus 로고
    • DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia-telangiectasia gene product
    • Hartley, K.O. et al. (1995) DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia-telangiectasia gene product. Cell, 82, 849-856.
    • (1995) Cell , vol.82 , pp. 849-856
    • Hartley, K.O.1
  • 22
    • 0026582702 scopus 로고
    • Caenorhabditis elegans gene ced-9 protects cells from programmed cell death
    • Hengartner, M.O., Ellis, R.E. and Horvitz, H.R. (1992) Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature, 356, 494-499.
    • (1992) Nature , vol.356 , pp. 494-499
    • Hengartner, M.O.1    Ellis, R.E.2    Horvitz, H.R.3
  • 23
    • 0029397873 scopus 로고
    • Ataxia-telangiectasia at the crossroads
    • Jackson, S.P. (1995) Ataxia-telangiectasia at the crossroads. Curr. Biol., 5, 1210-1212.
    • (1995) Curr. Biol. , vol.5 , pp. 1210-1212
    • Jackson, S.P.1
  • 24
    • 0024470862 scopus 로고
    • Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothesin, and other cytotoxic anticancer drugs: A cautionary note
    • Kaufmann, S.H. (1989) Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothesin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res., 49, 5870-5878.
    • (1989) Cancer Res. , vol.49 , pp. 5870-5878
    • Kaufmann, S.H.1
  • 25
    • 0027255417 scopus 로고
    • Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
    • Kaufmann, S.H., Desnoyers, S., Ohaviano, Y., Davidson, N.E. and Poirier, G.G. (1993) Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res., 53, 3976-3985.
    • (1993) Cancer Res. , vol.53 , pp. 3976-3985
    • Kaufmann, S.H.1    Desnoyers, S.2    Ohaviano, Y.3    Davidson, N.E.4    Poirier, G.G.5
  • 26
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, J.F.R., Wyllie, A.H. and Currie, A.R. (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer, 26, 239-257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 28
    • 0029069295 scopus 로고
    • ICE-like proteases in apoptosis
    • Kumar, S. (1995a) ICE-like proteases in apoptosis. Trends Biochem. Sci., 20, 198-202.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 198-202
    • Kumar, S.1
  • 29
    • 0028998012 scopus 로고
    • Inhibition of apoptosis by the expression of antisense Nedd2
    • Kumar, S. (1995b) Inhibition of apoptosis by the expression of antisense Nedd2. FEBS Lett., 368, 69-72.
    • (1995) FEBS Lett. , vol.368 , pp. 69-72
    • Kumar, S.1
  • 30
    • 0028846079 scopus 로고
    • Role of multiple cellular proteases in the execution of programmed cell death
    • Kumar, S. and Harvey, N.L. (1995) Role of multiple cellular proteases in the execution of programmed cell death. FEBS Lett., 375, 169-173.
    • (1995) FEBS Lett. , vol.375 , pp. 169-173
    • Kumar, S.1    Harvey, N.L.2
  • 31
    • 0029794385 scopus 로고    scopus 로고
    • The ICE family of cysteine proteases as effectors of cell death
    • in press
    • Kumar, S. and Lavin, M.F. (1996) The ICE family of cysteine proteases as effectors of cell death. Cell Death Different., in press.
    • (1996) Cell Death Different.
    • Kumar, S.1    Lavin, M.F.2
  • 32
    • 0027990778 scopus 로고
    • Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1β-converting enzyme
    • Kumar, S., Kinoshita, M., Noda, M., Copeland, N.G. and Jenkins, N.A. (1994) Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1β-converting enzyme. Genes Dev., 8, 1613-1626.
    • (1994) Genes Dev. , vol.8 , pp. 1613-1626
    • Kumar, S.1    Kinoshita, M.2    Noda, M.3    Copeland, N.G.4    Jenkins, N.A.5
  • 33
    • 0029062524 scopus 로고
    • Apoptosis regulatory gene NEDD2 maps to human chromosome segment 7q34-35, a region frequently affected in haematological neoplasms
    • Kumar, S., White, D.L., Takai, S., Turczynowicz, S., Juttner, C.A. and Hughes, T.P. (1995) Apoptosis regulatory gene NEDD2 maps to human chromosome segment 7q34-35, a region frequently affected in haematological neoplasms. Hum. Genet., 95, 641-644.
    • (1995) Hum. Genet. , vol.95 , pp. 641-644
    • Kumar, S.1    White, D.L.2    Takai, S.3    Turczynowicz, S.4    Juttner, C.A.5    Hughes, T.P.6
  • 35
    • 0028102478 scopus 로고
    • Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE
    • Lazebnik, Y.A., Kaufmann, S.H., Desmoyners, S., Poirier, G.G. and Earnshaw, W.C. (1994) Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE. Nature, 371, 346-347.
    • (1994) Nature , vol.371 , pp. 346-347
    • Lazebnik, Y.A.1    Kaufmann, S.H.2    Desmoyners, S.3    Poirier, G.G.4    Earnshaw, W.C.5
  • 37
  • 38
    • 0029125701 scopus 로고
    • Protease activation during apoptosis: Death by a thousand cuts
    • Martin, S.J. and Green, D.R. (1995) Protease activation during apoptosis: death by a thousand cuts. Cell, 82, 349-352.
    • (1995) Cell , vol.82 , pp. 349-352
    • Martin, S.J.1    Green, D.R.2
  • 40
    • 0029610432 scopus 로고
    • Identification of actin as a substrate of ICE and an ICE-like protease and involvement fo ICE-like protease but not ICE in VP-16-induced U937 apoptosis
    • Mashima, T., Naito, M., Fujita, N., Noguchi, K. and Tsuruo, T. (1995) Identification of actin as a substrate of ICE and an ICE-like protease and involvement fo ICE-like protease but not ICE in VP-16-induced U937 apoptosis. Biochem. Biophys. Res. Commun., 217, 1185-1192.
    • (1995) Biochem. Biophys. Res. Commun. , vol.217 , pp. 1185-1192
    • Mashima, T.1    Naito, M.2    Fujita, N.3    Noguchi, K.4    Tsuruo, T.5
  • 41
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cell
    • Miller, S.A., Dykes, D.D. and Polesky, H.F. (1988) A simple salting out procedure for extracting DNA from human nucleated cell. Nucleic Adds Res., 16, 1215.
    • (1988) Nucleic Adds Res. , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 43
    • 14844356354 scopus 로고
    • Degradation of lamin B1 precedes oligonucleosomal DNA fragmentation in apoptotic thymocytes and isolated thymocyte nuclei
    • Neamati, N., Fernandez, A., Wright, S., Kiefer, J. and McConkey, D.J. (1995) Degradation of lamin B1 precedes oligonucleosomal DNA fragmentation in apoptotic thymocytes and isolated thymocyte nuclei. J. Immunol., 154, 3788-3795.
    • (1995) J. Immunol. , vol.154 , pp. 3788-3795
    • Neamati, N.1    Fernandez, A.2    Wright, S.3    Kiefer, J.4    McConkey, D.J.5
  • 44
    • 0029068871 scopus 로고
    • Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
    • Nicholson, D.W. et al. (1995) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature, 376, 37-43.
    • (1995) Nature , vol.376 , pp. 37-43
    • Nicholson, D.W.1
  • 45
    • 0027458695 scopus 로고
    • Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death)
    • Peitsch, M.C., Potzar, B., Stephan, H., Crompton, T., MacDonald, H.R., Mannherz, H.G. and Tschopp, J. (1993) Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). EMBO J., 12, 371-377.
    • (1993) EMBO J. , vol.12 , pp. 371-377
    • Peitsch, M.C.1    Potzar, B.2    Stephan, H.3    Crompton, T.4    MacDonald, H.R.5    Mannherz, H.G.6    Tschopp, J.7
  • 46
    • 0028902932 scopus 로고
    • Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand break repair mutant mammalian cells
    • Peterson, S.R., Kurimasa, A., Oshimura, M., Dynan, W.S., Bradbury, E.M. and Chen, D. (1995) Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand break repair mutant mammalian cells. Proc. Natl Acad. Sci. USA, 92, 3171-3174.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 3171-3174
    • Peterson, S.R.1    Kurimasa, A.2    Oshimura, M.3    Dynan, W.S.4    Bradbury, E.M.5    Chen, D.6
  • 47
    • 0029057336 scopus 로고
    • A single ataxia-telangiectasia gene with a product similar to PI-3 kinase
    • Savitsky, K. et al. (1995) A single ataxia-telangiectasia gene with a product similar to PI-3 kinase. Science, 268, 1749-1793.
    • (1995) Science , vol.268 , pp. 1749-1793
    • Savitsky, K.1
  • 48
    • 0027479977 scopus 로고
    • Apoptosis: The biochemistry and molecular biology of programmed cell death
    • Schwartzmann, R.A. and Cidlowski, J.A. (1993) Apoptosis: the biochemistry and molecular biology of programmed cell death. Endocrinol. Rev., 14, 133-151.
    • (1993) Endocrinol. Rev. , vol.14 , pp. 133-151
    • Schwartzmann, R.A.1    Cidlowski, J.A.2
  • 49
    • 0001183734 scopus 로고
    • Ataxia-telangiectasia (208900; 208910; 208920)
    • de Jong, J.M.B.V. (ed.), Elsevier Science Publishers, Amsterdam
    • Sedgwick, R.P. and Boder, E. (1991) Ataxia-telangiectasia (208900; 208910; 208920). In de Jong, J.M.B.V. (ed.), Hereditary Neuropathies and Spinocerebellar Atrophies. Elsevier Science Publishers, Amsterdam, pp. 347-423.
    • (1991) Hereditary Neuropathies and Spinocerebellar Atrophies , pp. 347-423
    • Sedgwick, R.P.1    Boder, E.2
  • 50
    • 0028929328 scopus 로고
    • Mechanism and genes of cellular suicide
    • Steller, H. (1995) Mechanism and genes of cellular suicide. Science, 267, 1445-1449.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 51
    • 0029048498 scopus 로고
    • Life and death during lymphocyte development and function: Evidence for two distinct killing mechanisms
    • Strasser, A. (1995) Life and death during lymphocyte development and function: evidence for two distinct killing mechanisms. Curr. Opin. Immunol., 7, 228-234.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 228-234
    • Strasser, A.1
  • 52
    • 0028025020 scopus 로고
    • Ku 80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination
    • Taccioli, G.E. et al. (1994) Ku 80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. Science, 265, 1442-1445.
    • (1994) Science , vol.265 , pp. 1442-1445
    • Taccioli, G.E.1
  • 53
    • 0025718742 scopus 로고
    • Demonstration of the induction of apoptosis (programmed cell death) by tetrandrine, a novel anti-inflammatory agent
    • Teh, B.S., Chen, P., Lavin, M.F., Seow, W.K. and Thong, Y.H. (1991) Demonstration of the induction of apoptosis (programmed cell death) by tetrandrine, a novel anti-inflammatory agent. Int. J. Immunopharmacol., 13, 1117-1126.
    • (1991) Int. J. Immunopharmacol. , vol.13 , pp. 1117-1126
    • Teh, B.S.1    Chen, P.2    Lavin, M.F.3    Seow, W.K.4    Thong, Y.H.5
  • 54
    • 0028990125 scopus 로고
    • Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-Ribose) polymerase
    • Tewari, M., Quan, L.T., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D.R., Poirier, G.G., Salvesen, G.S. and Dixit, V.M. (1995a) Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-Ribose) polymerase. Cell, 81, 801-809.
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari, M.1    Quan, L.T.2    O'Rourke, K.3    Desnoyers, S.4    Zeng, Z.5    Beidler, D.R.6    Poirier, G.G.7    Salvesen, G.S.8    Dixit, V.M.9
  • 55
    • 0029102383 scopus 로고
    • CrmA-inhibitable cleavage of the 70 kDa protein component of the U1 small nuclear ribonucleoprotein during fas- and tumor necrosis factor-induced apoptosis
    • Tewari, M., Beidler, D.R. and Dixit, V.M. (1995b) CrmA-inhibitable cleavage of the 70 kDa protein component of the U1 small nuclear ribonucleoprotein during fas- and tumor necrosis factor-induced apoptosis. J. Biol. Chem., 270, 18738-18741.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18738-18741
    • Tewari, M.1    Beidler, D.R.2    Dixit, V.M.3
  • 57
    • 0027535559 scopus 로고
    • Towards an understanding of the molecular mechanisms of physiological cell death
    • Vaux, D.L. (1993) Towards an understanding of the molecular mechanisms of physiological cell death. Proc. Natl Acad. Sci. USA, 90, 786-789.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 786-789
    • Vaux, D.L.1
  • 58
    • 0028326952 scopus 로고
    • An evolutionary perspective on apoptosis
    • Vaux, D.L., Haecker, G. and Strasser, A. (1994) An evolutionary perspective on apoptosis. Cell, 76, 777-779.
    • (1994) Cell , vol.76 , pp. 777-779
    • Vaux, D.L.1    Haecker, G.2    Strasser, A.3
  • 59
    • 0028833024 scopus 로고
    • Activation of intracellular protease is an early event in TNF-induced apoptosis
    • Voelkel-Johnson, C., Entingh, A.J., Wold, W.S.M., Golding, L.-R. and Laster, S.M. (1995) Activation of intracellular protease is an early event in TNF-induced apoptosis. J. Immunol., 154, 1707-1716.
    • (1995) J. Immunol. , vol.154 , pp. 1707-1716
    • Voelkel-Johnson, C.1    Entingh, A.J.2    Wold, W.S.M.3    Golding, L.-R.4    Laster, S.M.5
  • 60
    • 0028168593 scopus 로고
    • IcH-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death
    • Wang, L., Miura, M., Bergeron, L., Zhu, H. and Yuan, J. (1994) IcH-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell, 78, 739-750.
    • (1994) Cell , vol.78 , pp. 739-750
    • Wang, L.1    Miura, M.2    Bergeron, L.3    Zhu, H.4    Yuan, J.5
  • 61
    • 0028922462 scopus 로고
    • Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease
    • Wang, Z.-Q., Auer, B., Sting, L., Berghammer, H., Haidacher, D., Schweigher, H. and Wagner, E.F. (1995) Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. Genes Dev., 9, 509-520.
    • (1995) Genes Dev. , vol.9 , pp. 509-520
    • Wang, Z.-Q.1    Auer, B.2    Sting, L.3    Berghammer, H.4    Haidacher, D.5    Schweigher, H.6    Wagner, E.F.7
  • 62
    • 0030046508 scopus 로고    scopus 로고
    • Life, death and the pursuit of apoptosis
    • White, E. (1996) Life, death and the pursuit of apoptosis. Genes Dev., 10, 1-15.
    • (1996) Genes Dev. , vol.10 , pp. 1-15
    • White, E.1
  • 63
  • 64
    • 0022902699 scopus 로고
    • A 10S particle released from deoxyribonuclease sensitive region of HeLa cell nuclei contains the 86-kilodalton-70-kilodalton protein complex
    • Yaneva, M. and Busch, H. (1986) A 10S particle released from deoxyribonuclease sensitive region of HeLa cell nuclei contains the 86-kilodalton-70-kilodalton protein complex. Biochemistry, 25, 5057-5063.
    • (1986) Biochemistry , vol.25 , pp. 5057-5063
    • Yaneva, M.1    Busch, H.2
  • 65
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
    • Yuan, J., Shaham, S., Ledoux, S., Ellis, H. and Horvitz, H.R. (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell, 75, 641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.4    Horvitz, H.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.