The conformational switch in 7-transmembrane receptors: The muscarinic receptor paradigm

European Journal of Pharmacology

Volumn 375, Issue 1-3, 1999, Pages 247-260

  Hulme, Edward C ^a   Lu, Zhi Liang ^a   Ward, Stuart D C ^a   Allman, Karen ^a   Curtis, Carol A M ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

7 Transmembrane receptor; Acetylcholine; G protein; G protein coupling pocket; Muscarinic receptor

Indexed keywords

ACETYLCHOLINE; CHLORMETHINE DERIVATIVE; GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE RECEPTOR; MUSCARINIC AGENT; MUSCARINIC RECEPTOR; TETRAMETHYLAMMONIUM;

BINDING SITE; CONFORMATIONAL TRANSITION; MAMMAL; MODEL; MUTAGENESIS; MUTATION; PRIORITY JOURNAL; PROTEIN TERTIARY STRUCTURE; REVIEW;

BINDING SITES; CELL MEMBRANE; GTP-BINDING PROTEINS; MOLECULAR CONFORMATION; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, CHOLINERGIC; RECEPTORS, MUSCARINIC;

EID: 0032983090     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00297-6     Document Type: Review

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