Structure and function in rhodopsin: Rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 26, 1997, Pages 14273-14278

  Kim, Jong Myoung ^a   Altenbach, Christian ^b   Thurmond, Robin L ^c   Khorana, H Gobind ^a   Hubbell, Wayne L ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b JULES STEIN EYE INSTITUTE   (United States)

^c Robert Wood Johnson P   (United States)

Author keywords

Constitutive activation; EPR; G protein coupled receptors; Signal transduction; Site directed spin labeling

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; RHODOPSIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; HUMAN; PHOTOACTIVATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ANIMALS; HUMANS; MUTATION; PHOTIC STIMULATION; PROTEIN CONFORMATION; RHODOPSIN; SIGNAL TRANSDUCTION;

EID: 0031446595     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.26.14273     Document Type: Article

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