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Volumn 7, Issue 3, 1999, Pages 77-102

Prospects for drug treatment of AIDS

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRASE; PROTEINASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; VIRUS RNA;

EID: 0032743120     PISSN: 13190164     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (2)

References (200)
  • 2
    • 0025904765 scopus 로고
    • Assembly and morphology of HIV: Potential effect of structure on viral function
    • Gelderblom HR Assembly and morphology of HIV: potential effect of structure on viral function. AIDS 1991; 5:617-638.
    • (1991) AIDS , vol.5 , pp. 617-638
    • Gelderblom, H.R.1
  • 3
    • 0031041708 scopus 로고    scopus 로고
    • Electron microscopic study of human immunodeficiency virus type-1 (HIV-1) core structure: Two RNA strands in the core of mature and budding particles
    • Takasaki T, Kurane I, Aihara H, Ohkaw N and Yamaguchi J. Electron microscopic study of human immunodeficiency virus type-1 (HIV-1) core structure: two RNA strands in the core of mature and budding particles. Arch Virol 1997; 142:375-382.
    • (1997) Arch Virol , vol.142 , pp. 375-382
    • Takasaki, T.1    Kurane, I.2    Aihara, H.3    Ohkaw, N.4    Yamaguchi, J.5
  • 4
    • 0026515142 scopus 로고
    • Gag proteins of the highly replicative MN strains of human immunodeficiency virus type 1: Posttranscriptional modifications, proteorytic processing and complete amino acid sequences
    • Henderson LE, Bower MA, Sowder RC, Serabin SA, Johnson DG, Bess JW, Arthur LO, Bryant DK and Fenselau C. Gag proteins of the highly replicative MN strains of human immunodeficiency virus type 1: posttranscriptional modifications, proteorytic processing and complete amino acid sequences. J Virol 1992; 66:1826-1865.
    • (1992) J Virol , vol.66 , pp. 1826-1865
    • Henderson, L.E.1    Bower, M.A.2    Sowder, R.C.3    Serabin, S.A.4    Johnson, D.G.5    Bess, J.W.6    Arthur, L.O.7    Bryant, D.K.8    Fenselau, C.9
  • 5
    • 0030964841 scopus 로고    scopus 로고
    • Recent aspects of HIV and HIV-related diseases
    • Gurtler L. Recent aspects of HIV and HIV-related diseases. Infection 1997; 25:71-73.
    • (1997) Infection , vol.25 , pp. 71-73
    • Gurtler, L.1
  • 8
    • 0031138207 scopus 로고    scopus 로고
    • HIV infection and acquired immunodeficiency syndrome
    • Takamatsu J. HIV infection and acquired immunodeficiency syndrome. Rinsho Byori 1997; 45:409-414.
    • (1997) Rinsho Byori , vol.45 , pp. 409-414
    • Takamatsu, J.1
  • 9
    • 0030582188 scopus 로고    scopus 로고
    • Global burden of the HIV pandemic
    • Quinn TC. Global burden of the HIV pandemic. Lancet 1996; 348:99-106.
    • (1996) Lancet , vol.348 , pp. 99-106
    • Quinn, T.C.1
  • 10
    • 0030887872 scopus 로고    scopus 로고
    • Human immunodeficiency virus infection in pregnant women and their newborns
    • Lindsay MK and Nesheim SR. Human immunodeficiency virus infection in pregnant women and their newborns. Clin Perinatol 1997; 24:161-180.
    • (1997) Clin Perinatol , vol.24 , pp. 161-180
    • Lindsay, M.K.1    Nesheim, S.R.2
  • 12
    • 0030858324 scopus 로고    scopus 로고
    • CD4: A co-receptor in the immune response and HIV infection
    • Bowers K, Pitcher C and Marsh M. CD4: A co-receptor in the immune response and HIV infection. Int J Biochem Cell Biol 1997; 29:871-875.
    • (1997) Int J Biochem Cell Biol , vol.29 , pp. 871-875
    • Bowers, K.1    Pitcher, C.2    Marsh, M.3
  • 15
    • 0029977510 scopus 로고    scopus 로고
    • Targeting HIV reverse transcriptase for anti-AIDS drug design: Structural and biological considerations for chemotherapeutic strategies
    • Discv
    • Arnold E, Das K, Ding J, Yudav P, Hsiou Y, Boyer P and Hughes S. Targeting HIV reverse transcriptase for anti-AIDS drug design: structural and biological considerations for chemotherapeutic strategies. Drug Des 1996; Discv 13:29-47.
    • (1996) Drug des , vol.13 , pp. 29-47
    • Arnold, E.1    Das, K.2    Ding, J.3    Yudav, P.4    Hsiou, Y.5    Boyer, P.6    Hughes, S.7
  • 16
    • 0028584269 scopus 로고
    • Crystal structure of the catalytic domain of HIV-1 integrase: Similarity to other polynucleotidyl transferases
    • Dyda F, Hickman AB and Jenkins TM. Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases. Science 1994; 266:1981-1986.
    • (1994) Science , vol.266 , pp. 1981-1986
    • Dyda, F.1    Hickman, A.B.2    Jenkins, T.M.3
  • 20
    • 17644429769 scopus 로고    scopus 로고
    • Inhibition of HIV transcription and virus replication using soluble Tat peptide analogues
    • Kashanachi F, Sadaie MR and Brady JM. Inhibition of HIV transcription and virus replication using soluble Tat peptide analogues. Virology 1997; 227:431-438.
    • (1997) Virology , vol.227 , pp. 431-438
    • Kashanachi, F.1    Sadaie, M.R.2    Brady, J.M.3
  • 21
    • 0029964107 scopus 로고    scopus 로고
    • Current knowledge and future prospects for the use of HIV protease inhibitors
    • Moyle G and Gazzard B. Current knowledge and future prospects for the use of HIV protease inhibitors. Drugs 1996; 51:701-712.
    • (1996) Drugs , vol.51 , pp. 701-712
    • Moyle, G.1    Gazzard, B.2
  • 22
    • 0030993833 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 protease inhibitors
    • McDonald CK and Kuritzkes DR Human immunodeficiency virus type 1 protease inhibitors. Arch Intern Med 1997; 157:951-959.
    • (1997) Arch Intern Med , vol.157 , pp. 951-959
    • McDonald, C.K.1    Kuritzkes, D.R.2
  • 23
    • 0031568694 scopus 로고    scopus 로고
    • Recent advances HIV infection-I
    • Conn JA. Recent advances HIV infection-I BMJ 1997; 314:487-491.
    • (1997) BMJ , vol.314 , pp. 487-491
    • Conn, J.A.1
  • 24
    • 0031020973 scopus 로고    scopus 로고
    • Perspective: Research highlights at Baylor center for AIDS research. The immune system in vertical HIV infection: The immune response and disease progression
    • Paul ME. Perspective: Research highlights at Baylor center for AIDS research. The immune system in vertical HIV infection: the immune response and disease progression. AIDS Res Hum Retroviruses 1997; 13:1-4.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 1-4
    • Paul, M.E.1
  • 26
    • 0029967721 scopus 로고    scopus 로고
    • HIV dynamics in vivo:virion clearance rate, infected cell life-span and viral generation time
    • Perelson AS, Neumann AU, Markowitz M, Leonard JM and Ho DD. HIV dynamics in vivo:virion clearance rate, infected cell life-span and viral generation time. Science 1996; 271:1582-1586.
    • (1996) Science , vol.271 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 29
    • 0028785967 scopus 로고
    • Role of apoptosis in HIV disease pathogenesis
    • Oyaizu JC and Pahwa S. Role of apoptosis in HIV disease pathogenesis. J Clin Immunol 1995; 15:217-231.
    • (1995) J Clin Immunol , vol.15 , pp. 217-231
    • Oyaizu, J.C.1    Pahwa, S.2
  • 30
    • 0030795491 scopus 로고    scopus 로고
    • Time course of viremia and antibody seroconversion following human immunodeficiency virus exposure
    • Busch MP and Satten GA. Time course of viremia and antibody seroconversion following human immunodeficiency virus exposure. Am J Med 1997; 102:117-124.
    • (1997) Am J Med , vol.102 , pp. 117-124
    • Busch, M.P.1    Satten, G.A.2
  • 31
    • 0030052938 scopus 로고    scopus 로고
    • Plasma viral load, CD4 cell counts, and HIV-1 production by cells
    • Levy JA. Plasma viral load, CD4 cell counts, and HIV-1 production by cells. Science 1996; 271:670-671.
    • (1996) Science , vol.271 , pp. 670-671
    • Levy, J.A.1
  • 33
    • 0030665927 scopus 로고    scopus 로고
    • Apoptosis: Clinical relevance and pharmacological manipulation
    • Thatte U and Dahanukar S. Apoptosis: clinical relevance and pharmacological manipulation. Drugs 1997; 54:511-532.
    • (1997) Drugs , vol.54 , pp. 511-532
    • Thatte, U.1    Dahanukar, S.2
  • 34
    • 0342814308 scopus 로고    scopus 로고
    • Increased CD95 (APO-1/Fas) ligand expression in T cells of HTV-1 infected children
    • Baumler CB, Herr I, Bohler T, Krammer PH and Debatin KM. Increased CD95 (APO-1/Fas) ligand expression in T cells of HTV-1 infected children. Blood 1996; 88:1741-1748.
    • (1996) Blood , vol.88 , pp. 1741-1748
    • Baumler, C.B.1    Herr, I.2    Bohler, T.3    Krammer, P.H.4    Debatin, K.M.5
  • 38
    • 0030760670 scopus 로고    scopus 로고
    • Apoptosis and the immune system
    • Ekert PG and Voux DL. Apoptosis and the immune system. Br Med Bul 1997; 53:591-603.
    • (1997) Br Med Bul , vol.53 , pp. 591-603
    • Ekert, P.G.1    Voux, D.L.2
  • 40
    • 0029062573 scopus 로고
    • Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein
    • Li CJ, Friedman DJ, Wang C, Metelev V and Pardee AB. Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science 1995; 268:429-431.
    • (1995) Science , vol.268 , pp. 429-431
    • Li, C.J.1    Friedman, D.J.2    Wang, C.3    Metelev, V.4    Pardee, A.B.5
  • 41
    • 0027458469 scopus 로고
    • Release, uptake and effects of extracellular HIV-1 Tar protein on cell growth and viral transactivation
    • Ensoli B, Buonaguro L and Barillar G. Release, uptake and effects of extracellular HIV-1 Tar protein on cell growth and viral transactivation. J Virol 1993; 67:277-287.
    • (1993) J Virol , vol.67 , pp. 277-287
    • Ensoli, B.1    Buonaguro, L.2    Barillar, G.3
  • 42
    • 2442748511 scopus 로고
    • Oxidative stress, HIV and AIDS: The basis for antioxidant-oriented antiretroviral nucleoside analogues
    • Abou-Shaaban RA. Oxidative stress, HIV and AIDS: The basis for antioxidant-oriented antiretroviral nucleoside analogues. SPJ 1995; 3:1-22.
    • (1995) SPJ , vol.3 , pp. 1-22
    • Abou-Shaaban, R.A.1
  • 43
    • 0028861429 scopus 로고
    • HIV-1 Tat potentiates TNF-induced NF-κ activation and cytotoxicity by altering cellular redox state
    • Westendrop MO, Shatrov VA and Schulze-Osthoff K. HIV-1 Tat potentiates TNF-induced NF-κ activation and cytotoxicity by altering cellular redox state. EMBO J 1995; 14:546-554.
    • (1995) EMBO J , vol.14 , pp. 546-554
    • Westendrop, M.O.1    Shatrov, V.A.2    Schulze-Osthoff, K.3
  • 44
    • 0029818586 scopus 로고    scopus 로고
    • Resistance of chimpanzee T cell to human immunodeficiency virus type-1 tat-enhanced oxidative stress and apoptosis
    • Ehret A, Westendrop MO and Herr I. Resistance of chimpanzee T cell to human immunodeficiency virus type-1 tat-enhanced oxidative stress and apoptosis. J Virol 1996; 70:6502-6507.
    • (1996) J Virol , vol.70 , pp. 6502-6507
    • Ehret, A.1    Westendrop, M.O.2    Herr, I.3
  • 45
    • 0030980813 scopus 로고    scopus 로고
    • Zinc ejection as a new rationale for the use of cystamine and related disulfide-containing antiviral agents in the treatment of AIDS
    • McDonnel NB, De Guzman RN, Rice WG, Turpin JA and Summers MF. Zinc ejection as a new rationale for the use of cystamine and related disulfide-containing antiviral agents in the treatment of AIDS. J Med Chem 1997; 40:1969-1976.
    • (1997) J Med Chem , vol.40 , pp. 1969-1976
    • McDonnel, N.B.1    De Guzman, R.N.2    Rice, W.G.3    Turpin, J.A.4    Summers, M.F.5
  • 46
    • 0030714995 scopus 로고    scopus 로고
    • Selenium supplementation suppresses tumor necrosis factor alpha-induced human immunodeficiency virus type 1 replication in vitro
    • Hori K, Hatfield D. Maldarelli F, Lee BJ and Clouse KA. Selenium supplementation suppresses tumor necrosis factor alpha-induced human immunodeficiency virus type 1 replication in vitro. AIDS Res Hum Retroviruses 1997; 13:1325-1332.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 1325-1332
    • Hori, K.1    Hatfield, D.2    Maldarelli, F.3    Lee, B.J.4    Clouse, K.A.5
  • 48
    • 0029999656 scopus 로고    scopus 로고
    • Bcl-2 down-regulates the activity of transcription factor NF-κB induced upon apoptosis
    • Grimm S, Bauer MKA, Baeuerle PA and Schulze-Odthoff K. Bcl-2 down-regulates the activity of transcription factor NF-κB induced upon apoptosis. J Cell Biol 1996; 134:13-23.
    • (1996) J Cell Biol , vol.134 , pp. 13-23
    • Grimm, S.1    Bauer, M.K.A.2    Baeuerle, P.A.3    Schulze-Odthoff, K.4
  • 49
    • 0029833902 scopus 로고    scopus 로고
    • A hydrophobic region of the adenovirus E1B 19 kDa protein is necessary for the transient inhibition of NF-κB activated by different stimuli
    • Limbourg FP, Stadtler G, Chinnadurai G, Baeuerle PA and Schmitz ML. A hydrophobic region of the adenovirus E1B 19 kDa protein is necessary for the transient inhibition of NF-κB activated by different stimuli. J Biol Chem 1996; 271:20392-20398.
    • (1996) J Biol Chem , vol.271 , pp. 20392-20398
    • Limbourg, F.P.1    Stadtler, G.2    Chinnadurai, G.3    Baeuerle, P.A.4    Schmitz, M.L.5
  • 50
    • 0030979523 scopus 로고    scopus 로고
    • Reactive oxygen species and nitric oxide in viral diseases
    • Peterhans E. Reactive oxygen species and nitric oxide in viral diseases. Biol Trace Elem Res 1997; 56:107-116.
    • (1997) Biol Trace Elem Res , vol.56 , pp. 107-116
    • Peterhans, E.1
  • 51
    • 0030872636 scopus 로고    scopus 로고
    • Cytotoxic monocytes in the blood of HIV type 1-infected subjects destroy targeted T cells in a CD95-dependent fashion
    • Orlikowsky T, Wang Z, Dudhane A, Horowitz H, Riethmuller G and Hoffmann MK. Cytotoxic monocytes in the blood of HIV type 1-infected subjects destroy targeted T cells in a CD95-dependent fashion. AIDS Res Hum Retroviruses 1997; 13:953-958.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 953-958
    • Orlikowsky, T.1    Wang, Z.2    Dudhane, A.3    Horowitz, H.4    Riethmuller, G.5    Hoffmann, M.K.6
  • 53
    • 0029821787 scopus 로고    scopus 로고
    • CD95 (APO-1/Fas) induces activation of SAP kinases downstream ICE-like proteases
    • Cahill MA, Peter ME and Kischkel FC. CD95 (APO-1/Fas) induces activation of SAP kinases downstream ICE-like proteases. oncogene 1996; 13:2087-2096.
    • (1996) Oncogene , vol.13 , pp. 2087-2096
    • Cahill, M.A.1    Peter, M.E.2    Kischkel, F.C.3
  • 54
    • 0031058025 scopus 로고    scopus 로고
    • The inhibition of pro-apoptotic ICE-like proteases enhances HIV replication
    • Chinnalyan AM, Woffendin C, Dixit VM and Nabel GJ. The inhibition of pro-apoptotic ICE-like proteases enhances HIV replication. Nat Med 1997; 3:333-337.
    • (1997) Nat Med , vol.3 , pp. 333-337
    • Chinnalyan, A.M.1    Woffendin, C.2    Dixit, V.M.3    Nabel, G.J.4
  • 57
    • 0030906720 scopus 로고    scopus 로고
    • Use of HIV viral load in clinical practice: Back to the future
    • Saag MS. Use of HIV viral load in clinical practice: Back to the future. Ann Intern Med 1997; 126:983-985.
    • (1997) Ann Intern Med , vol.126 , pp. 983-985
    • Saag, M.S.1
  • 58
    • 0029078820 scopus 로고    scopus 로고
    • + count of 500 cell/μl
    • + count of 500 cell/μl. Drugs 1996; 49:4-8.
    • (1996) Drugs , vol.49 , pp. 4-8
    • Volberding, P.1
  • 59
    • 0031052933 scopus 로고    scopus 로고
    • Human immunodeficiency virus (HIV) RNa in plasma as the preferred target for therapy in patients with HIV infection: A critique
    • Fessel WJ. Human immunodeficiency virus (HIV) RNA in plasma as the preferred target for therapy in patients with HIV infection: a critique. Clin Infect Dis 1997; 24:116-122.
    • (1997) Clin Infect Dis , vol.24 , pp. 116-122
    • Fessel, W.J.1
  • 61
    • 0029075002 scopus 로고
    • Perspectives in drug therapy of HIV infection
    • Darbyshire J. Perspectives in drug therapy of HIV infection. Drugs 1995; 49:1-3.
    • (1995) Drugs , vol.49 , pp. 1-3
    • Darbyshire, J.1
  • 62
    • 0029803970 scopus 로고    scopus 로고
    • Changing therapy in HIV
    • Lange JMA. Changing therapy in HIV. AIDS 1996; 10:S27-S30.
    • (1996) AIDS , vol.10
    • Lange, J.M.A.1
  • 63
    • 0030948565 scopus 로고    scopus 로고
    • Current problems and the future of antiretroviral drug trials
    • Lange JMA. Current problems and the future of antiretroviral drug trials. Science 1997; 276:548-550.
    • (1997) Science , vol.276 , pp. 548-550
    • Lange, J.M.A.1
  • 64
    • 0031183153 scopus 로고    scopus 로고
    • Preliminary evidence for partial restoration of immune function in HIV-type 1 infection with potent antiretroviral therapies: Clues from the 4th Conference on Retroviruses and Opportunistic Diseases
    • Schnittman SM and Fox L. Preliminary evidence for partial restoration of immune function in HIV-type 1 infection with potent antiretroviral therapies: Clues from the 4th Conference on Retroviruses and Opportunistic Diseases. AIDS Res Hum Retroviruses 1997; 13:815-818.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 815-818
    • Schnittman, S.M.1    Fox, L.2
  • 65
    • 0027523676 scopus 로고
    • Antiviral therapy in human immunodeficiency virus infections. Current status (part I)
    • Sandstrom E and Oberg B. Antiviral therapy in human immunodeficiency virus infections. Current status (part I). Drugs 1993; 45:488-508.
    • (1993) Drugs , vol.45 , pp. 488-508
    • Sandstrom, E.1    Oberg, B.2
  • 66
    • 0023578993 scopus 로고
    • Failure of dideoxynucleotides to inhibit human immunodeficiency virus replication in cultured human macrophages
    • Richman DD, Kornbluth RS and Carson DA. Failure of dideoxynucleotides to inhibit human immunodeficiency virus replication in cultured human macrophages. J Exp Med 1987; 166:1144-1149.
    • (1987) J Exp Med , vol.166 , pp. 1144-1149
    • Richman, D.D.1    Kornbluth, R.S.2    Carson, D.A.3
  • 67
    • 0026635104 scopus 로고
    • Clinical pharmacokineticx of 3′-azido-3′-deoxythymidine (zidovudine) and catabolites with formation of cytotoxic catabolites, 3′ amino-3′-deoxythymidine
    • Stagg MP, Cretton EM, Kidd L, Diasio RB and Sommadossi JP. Clinical pharmacokineticx of 3′-azido-3′-deoxythymidine (zidovudine) and catabolites with formation of cytotoxic catabolites, 3′ amino-3′-deoxythymidine. Clin Pharmacol Ther 1992; 51:668-676.
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 668-676
    • Stagg, M.P.1    Cretton, E.M.2    Kidd, L.3    Diasio, R.B.4    Sommadossi, J.P.5
  • 68
    • 0025760081 scopus 로고
    • Remarkable improvements of neuropsychatric symptoms in HIV-infected patients after AZT-therapy
    • Hollweg M, Riedel RR, Goebel FD, Schick U and Naber D. Remarkable improvements of neuropsychatric symptoms in HIV-infected patients after AZT-therapy. Klinische Wochenschnift 1991; 69:409-412.
    • (1991) Klinische Wochenschnift , vol.69 , pp. 409-412
    • Hollweg, M.1    Riedel, R.R.2    Goebel, F.D.3    Schick, U.4    Naber, D.5
  • 69
    • 0026563485 scopus 로고    scopus 로고
    • Incidence of AIDS dementia in a two-year follow-up of AIDS and ARC patients on initial phase II zidovudine placebo controlled study
    • Day JJ, Grant I, Atkinson JH, Brysk LT and McCuthan JA. Incidence of AIDS dementia in a two-year follow-up of AIDS and ARC patients on initial phase II zidovudine placebo controlled study. J Neuropsych Clin Neurosc 1997; 4:15-20.
    • (1997) J Neuropsych Clin Neurosc , vol.4 , pp. 15-20
    • Day, J.J.1    Grant, I.2    Atkinson, J.H.3    Brysk, L.T.4    McCuthan, J.A.5
  • 70
    • 0031037992 scopus 로고    scopus 로고
    • Zidovudine and thymus humoral factor gamma-2 in the treatment of HIV infection: Preliminary clinical experience
    • Maggiolo F, Taras A, Pravettoni G, Leone M, Ingrosso A and Suter F. Zidovudine and thymus humoral factor gamma-2 in the treatment of HIV infection: Preliminary clinical experience. Infection 1997; 25:35-40.
    • (1997) Infection , vol.25 , pp. 35-40
    • Maggiolo, F.1    Taras, A.2    Pravettoni, G.3    Leone, M.4    Ingrosso, A.5    Suter, F.6
  • 71
    • 0000263155 scopus 로고    scopus 로고
    • Update. Provisional recommendations for chemoprophylaxis after occupational exposure to human immunodeficiency virus
    • Centers for Disease Control and Prevention. Update. Provisional recommendations for chemoprophylaxis after occupational exposure to human immunodeficiency virus. MMWR 1996; 45:468-472.
    • (1996) MMWR , vol.45 , pp. 468-472
  • 72
    • 0030845857 scopus 로고    scopus 로고
    • Prophylaxis after occupational exposure to HIV
    • Easter PG. Prophylaxis after occupational exposure to HIV. BMJ 1997; 315:557-558.
    • (1997) BMJ , vol.315 , pp. 557-558
    • Easter, P.G.1
  • 74
    • 0028003766 scopus 로고
    • Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment
    • Conner EM, Sperling RS and Gelber R. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment N Engl J Med 1994, 331:1173-1180.
    • (1994) N Engl J Med , vol.331 , pp. 1173-1180
    • Conner, E.M.1    Sperling, R.S.2    Gelber, R.3
  • 75
    • 10544245018 scopus 로고    scopus 로고
    • Maternal viral load, zidovudine treatment and the risk of transmission of HIV-1 from mother to infant
    • Sperling SR, Shapiro DE and Coombs RW. maternal viral load, zidovudine treatment and the risk of transmission of HIV-1 from mother to infant. N Engl J Med 1996; 335:1621-1629.
    • (1996) N Engl J Med , vol.335 , pp. 1621-1629
    • Sperling, S.R.1    Shapiro, D.E.2    Coombs, R.W.3
  • 76
    • 85058722356 scopus 로고    scopus 로고
    • Prevention of mother-to-infant transmission of HIV-1
    • Melvin AJ and Frentel LM. Prevention of mother-to-infant transmission of HIV-1. Mol Med Today 1997; 3:842-845.
    • (1997) Mol Med Today , vol.3 , pp. 842-845
    • Melvin, A.J.1    Frentel, L.M.2
  • 77
    • 0030795482 scopus 로고    scopus 로고
    • Efficacy of zidovudine in preventing HIV transmission from mother to infant
    • Balsley J. Efficacy of zidovudine in preventing HIV transmission from mother to infant. Am J Med 1997; 102:45-46.
    • (1997) Am J Med , vol.102 , pp. 45-46
    • Balsley, J.1
  • 78
    • 0026547599 scopus 로고
    • A controlled trial of early versus late treatment with zidovudine in symptomatic HIV infection
    • Hamilton JD, Hartigan PM, Simberkoff MS, Day PL and Diamond GR. A controlled trial of early versus late treatment with zidovudine in symptomatic HIV infection. N Engl J Med 1992; 326:437-443.
    • (1992) N Engl J Med , vol.326 , pp. 437-443
    • Hamilton, J.D.1    Hartigan, P.M.2    Simberkoff, M.S.3    Day, P.L.4    Diamond, G.R.5
  • 81
    • 0028906281 scopus 로고
    • The efficacy of zidovudine compared to didanosine in patients with advanced HIV-1 infection and little or no previous experiences with zidovudine
    • Dolin R, Amato DA and Fischl MA. The efficacy of zidovudine compared to didanosine in patients with advanced HIV-1 infection and little or no previous experiences with zidovudine. Arch Intern Med 1995; 155:961-974.
    • (1995) Arch Intern Med , vol.155 , pp. 961-974
    • Dolin, R.1    Amato, D.A.2    Fischl, M.A.3
  • 82
    • 0027957908 scopus 로고
    • Didanosine compared with continuation of zidovudine in HIV-infected patients with signs of clinical deterioration while receiving zidovudine. A randomized, double blind clinical trial
    • Spruance SL, Pavia AT and Deterson D. Didanosine compared with continuation of zidovudine in HIV-infected patients with signs of clinical deterioration while receiving zidovudine. A randomized, double blind clinical trial. Ann Intern Med 1994; 120:360-368.
    • (1994) Ann Intern Med , vol.120 , pp. 360-368
    • Spruance, S.L.1    Pavia, A.T.2    Deterson, D.3
  • 83
    • 0030918031 scopus 로고    scopus 로고
    • Zalcitabine: An update of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of HIV infection
    • Adkins JC, Peters DH and Faulds D. Zalcitabine: an update of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of HIV infection. Drugs 1997; 53:1054-1080.
    • (1997) Drugs , vol.53 , pp. 1054-1080
    • Adkins, J.C.1    Peters, D.H.2    Faulds, D.3
  • 84
    • 0030833565 scopus 로고    scopus 로고
    • Combination chemotherapy for human immunodeficiency virus 1
    • Manion DJ and Hirsch MS. Combination chemotherapy for human immunodeficiency virus 1. Am J Med 1997; 102:76-80.
    • (1997) Am J Med , vol.102 , pp. 76-80
    • Manion, D.J.1    Hirsch, M.S.2
  • 85
    • 0030754485 scopus 로고    scopus 로고
    • DeClercq Development of resistance of human immunodeficiency virus (HIV) to anti-HIV agents: How to prevent the problem?
    • DeClercq Development of resistance of human immunodeficiency virus (HIV) to anti-HIV agents: how to prevent the problem? Int J Antimicrob Agents 1997; 9:21-36.
    • (1997) Int J Antimicrob Agents , vol.9 , pp. 21-36
  • 86
    • 0030899204 scopus 로고    scopus 로고
    • Lamivudine: A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in the management of HIV infection
    • Perry CM and Faulds D. Lamivudine: A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in the management of HIV infection. Drugs 1997; 53:1054-1080.
    • (1997) Drugs , vol.53 , pp. 1054-1080
    • Perry, C.M.1    Faulds, D.2
  • 88
    • 0030997937 scopus 로고    scopus 로고
    • Randomized trial of addition of lamivudine or lamivudine plus loviride to zidovudine-containing regimens for patients with HIV-1 infection: The Caesar Trial
    • CAESAR Coordinating Committee. Randomized trial of addition of lamivudine or lamivudine plus loviride to zidovudine-containing regimens for patients with HIV-1 infection: The Caesar Trial. Lancet 1997; 349:1413-1421.
    • (1997) Lancet , vol.349 , pp. 1413-1421
  • 89
    • 0028332029 scopus 로고
    • Novel mutation (V75T) in human immunodeficincy virus type-1 reverse transcriptase confers resistance to 2′3′-dihydro-2′3′-dideoxythymidine in cell culture
    • Lacey SF and Larder BA. Novel mutation (V75T) in human immunodeficincy virus type-1 reverse transcriptase confers resistance to 2′3′-dihydro-2′3′-dideoxythymidine in cell culture. Antimicrob Agents Chemoher 1994; 38:1428-1432.
    • (1994) Antimicrob Agents Chemoher , vol.38 , pp. 1428-1432
    • Lacey, S.F.1    Larder, B.A.2
  • 90
    • 0027988547 scopus 로고
    • Genotypic and phenotypic analysis of human immunodeficiency virus type 1 isolates from patients on prolonged stavudine therapy
    • Lin PF, Samanta H and Rose RE. Genotypic and phenotypic analysis of human immunodeficiency virus type 1 isolates from patients on prolonged stavudine therapy. J Infect Dis 1994; 170:1157-1164.
    • (1994) J Infect Dis , vol.170 , pp. 1157-1164
    • Lin, P.F.1    Samanta, H.2    Rose, R.E.3
  • 91
    • 0026648207 scopus 로고
    • Treatment of HIV-related cytromegalovirus disease of the gastrointestinal tract with foscarnet
    • Blanshard C. Treatment of HIV-related cytromegalovirus disease of the gastrointestinal tract with foscarnet. J Acq Immun Defic Synd 1992; 5:S25-S28.
    • (1992) J Acq Immun Defic Synd , vol.5
    • Blanshard, C.1
  • 92
    • 0028233222 scopus 로고
    • CMV prophylaxis with foscarnet in allogenic bone marrow transport recipients at high risk of developing CMV infections
    • Bacigalupo A, Tedone E and Vanlint MT. CMV prophylaxis with foscarnet in allogenic bone marrow transport recipients at high risk of developing CMV infections. Bone Marrow Transplant 1993; 13:783-788.
    • (1993) Bone Marrow Transplant , vol.13 , pp. 783-788
    • Bacigalupo, A.1    Tedone, E.2    Vanlint, M.T.3
  • 93
    • 0027479338 scopus 로고
    • Foscarnet-induced hypomagnesemia and other electrolyte disorders
    • Gearhart MO and Sorg TB. Foscarnet-induced hypomagnesemia and other electrolyte disorders. Ann Pharmacol 1993; 27:285-289.
    • (1993) Ann Pharmacol , vol.27 , pp. 285-289
    • Gearhart, M.O.1    Sorg, T.B.2
  • 95
    • 0031033530 scopus 로고    scopus 로고
    • Renal excretion and pharmacokinetics of foscarnet in HIV seropositive patients: Effect of probenecid pretreatment
    • Noormohamed FH, Youle MS, Higgs CJ, Gazzard BG and Lant AF. Renal excretion and pharmacokinetics of foscarnet in HIV seropositive patients: effect of probenecid pretreatment. Br J Clin Pharmacol 1997;43:112-123.
    • (1997) Br J Clin Pharmacol , vol.43 , pp. 112-123
    • Noormohamed, F.H.1    Youle, M.S.2    Higgs, C.J.3    Gazzard, B.G.4    Lant, A.F.5
  • 97
    • 0030011406 scopus 로고    scopus 로고
    • Pyrrolobenzothiiazepinone and pyrrolobenzoxazepinones: Novel and specific non-nucleoside HIV-reverse transcriptase inhibitors with antiviral activity
    • Campiani O, Nacci V, Fiorini I, De Filippis M, Garofalo A, Greco G, Novellino E, Altamura S and Di-Renzo L. Pyrrolobenzothiiazepinone and pyrrolobenzoxazepinones: Novel and specific non-nucleoside HIV-reverse transcriptase inhibitors with antiviral activity. J Med Chem 1996; 39:2672-2680.
    • (1996) J Med Chem , vol.39 , pp. 2672-2680
    • Campiani, O.1    Nacci, V.2    Fiorini, I.3    De Filippis, M.4    Garofalo, A.5    Greco, G.6    Novellino, E.7    Altamura, S.8    Di-Renzo, L.9
  • 100
    • 0025812546 scopus 로고
    • Anti-HIV agents: Synthesis and in vitro anti-HIV activity of novel 1H, 3H-thiazolo3,4- (a) benimidazoles
    • Chimrri A, Grasso S, Monforte AM, Monforte P and Zappala M. Anti-HIV agents: synthesis and in vitro anti-HIV activity of novel 1H, 3H-thiazolo[3,4-(a) benimidazoles. Farmaco 1991; 46:925-933.
    • (1991) Farmaco , vol.46 , pp. 925-933
    • Chimrri, A.1    Grasso, S.2    Monforte, A.M.3    Monforte, P.4    Zappala, M.5
  • 105
    • 0029761518 scopus 로고    scopus 로고
    • Nevirapine: A review of its development, pharmacological profile and potential for clinical use
    • Murphy RL and Montaner J. Nevirapine: a review of its development, pharmacological profile and potential for clinical use. Exp Opin Invest Drugs 1996; 5:1183-1199.
    • (1996) Exp Opin Invest Drugs , vol.5 , pp. 1183-1199
    • Murphy, R.L.1    Montaner, J.2
  • 106
    • 0029804757 scopus 로고    scopus 로고
    • Differences in the inhibition of human immunodeficiency virus type 11 reverse transcriptase DNA polymerase activity by analogues of nevirapine and [2′,5′-bis-O-ter-butyldimethylsily10-3′-spiro-5″- 4″-amino;-1″2″-Oxathiole-2″,2″dioxide] (TASO)
    • Arion D, Fletcher R, Borkow G, Camarasa M, Balzarini J, Dmitrienko G and Parniak M. Differences in the inhibition of human immunodeficiency virus type 11 reverse transcriptase DNA polymerase activity by analogues of nevirapine and [2′,5′-bis-O-(ter-butyldimethylsily10-3′-spiro-5″- (4″-amino;-1″2″-Oxathiole-2″,2″dioxide] (TASO). Mol Pharmacol 1996; 50:1057-1064.
    • (1996) Mol Pharmacol , vol.50 , pp. 1057-1064
    • Arion, D.1    Fletcher, R.2    Borkow, G.3    Camarasa, M.4    Balzarini, J.5    Dmitrienko, G.6    Parniak, M.7
  • 108
    • 0027173057 scopus 로고
    • Antiviral therapy in human immunodeficiency virus infections. Current status (part II)
    • Sandstorm E and Oberg B. Antiviral therapy in human immunodeficiency virus infections. Current status (part II). Drugs 1993; 45:637-653.
    • (1993) Drugs , vol.45 , pp. 637-653
    • Sandstorm, E.1    Oberg, B.2
  • 109
  • 110
    • 0030902816 scopus 로고    scopus 로고
    • HIV integrase: A target for AIDS therapeutics
    • Thomas M and Brady L. HIV integrase: a target for AIDS therapeutics. Trends Biotechnol 1997; 15:167-172.
    • (1997) Trends Biotechnol , vol.15 , pp. 167-172
    • Thomas, M.1    Brady, L.2
  • 111
    • 0025812772 scopus 로고
    • Inhibition of the RNase H activity of HIV reverse transcriptase to azidothymidylate
    • Tan CK, Civil R, Mian A, So A and Dowrey K. Inhibition of the RNase H activity of HIV reverse transcriptase to azidothymidylate. Biochem 1991; 30:4831-4835.
    • (1991) Biochem , vol.30 , pp. 4831-4835
    • Tan, C.K.1    Civil, R.2    Mian, A.3    So, A.4    Dowrey, K.5
  • 112
    • 0028041714 scopus 로고
    • Progress towards gene therapy for HIV infection
    • Yu M, Poeschla E and Wong-Staal F. Progress towards gene therapy for HIV infection. Gene Ther 1994; 1:13-26.
    • (1994) Gene Ther , vol.1 , pp. 13-26
    • Yu, M.1    Poeschla, E.2    Wong-Staal, F.3
  • 113
    • 0027371069 scopus 로고
    • Systemic expression of HIV-1 Tat gene in transgenic mice induces endothelial proliferation of tumors of different histotypes
    • Corallini A, Altavilla G, Pozzi L, Bignozzi F, Negrini M, Rimessi P, Gualondi F and Barbanti-Brodano G. Systemic expression of HIV-1 Tat gene in transgenic mice induces endothelial proliferation of tumors of different histotypes. Cancer Res 1993; 53:5569-5575.
    • (1993) Cancer Res , vol.53 , pp. 5569-5575
    • Corallini, A.1    Altavilla, G.2    Pozzi, L.3    Bignozzi, F.4    Rimessi P, N.M.5    Gualondi, F.6    Barbanti-Brodano, G.7
  • 114
    • 0031014829 scopus 로고    scopus 로고
    • Gene therapy for HIV infection
    • Morgan RA Gene therapy for HIV infection. Clin Exp Immunol 1997; 107:41-44.
    • (1997) Clin Exp Immunol , vol.107 , pp. 41-44
    • Morgan, R.A.1
  • 116
    • 0027727906 scopus 로고
    • A study of the safety and survival of the adoptive transfer of genetically marked syngenic lympocytes in HIV-infected identical twins
    • Walker R, Blaese RM, Carter CS and Chang L.. A study of the safety and survival of the adoptive transfer of genetically marked syngenic lympocytes in HIV-infected identical twins. Hum Gene Ther 1993; 4:659-680.
    • (1993) Hum Gene Ther , vol.4 , pp. 659-680
    • Walker, R.1    Blaese, R.M.2    Carter, C.S.3    Chang, L.4
  • 117
    • 0030041957 scopus 로고    scopus 로고
    • Update on the issues of HIV vaccine development
    • Haynes BF, Putman SB and Weinberg JB. Update on the issues of HIV vaccine development. Ann Med 1996; 28:39-41.
    • (1996) Ann Med , vol.28 , pp. 39-41
    • Haynes, B.F.1    Putman, S.B.2    Weinberg, J.B.3
  • 118
    • 0026484826 scopus 로고
    • Cell biology of antigen processing and presentation of MHC class I molecule restricted T lymphocyte
    • Yewdell J and Bennick J. Cell biology of antigen processing and presentation of MHC class I molecule restricted T lymphocyte. Adv Immunol 1992; 52:1-123.
    • (1992) Adv Immunol , vol.52 , pp. 1-123
    • Yewdell, J.1    Bennick, J.2
  • 119
    • 0027284896 scopus 로고
    • Gene inoculation generates immune response against HIV-1
    • Wang B, Ugen D and Srikantan V. Gene inoculation generates immune response against HIV-1. PNAS 1993; 90:4156-514160.
    • (1993) PNAS , vol.90 , pp. 4156-514160
    • Wang, B.1    Ugen, D.2    Srikantan, V.3
  • 120
    • 0025789888 scopus 로고
    • Cytotoxic T cells specific for cytomegalovirus: A potential therapy for immunocompromized patients
    • Riddell SR, Reusser P and Greenberg PD. Cytotoxic T cells specific for cytomegalovirus: a potential therapy for immunocompromized patients. Rev Infect Dis 1991; 3:S966-S973.
    • (1991) Rev Infect Dis , vol.3
    • Riddell, S.R.1    Reusser, P.2    Greenberg, P.D.3
  • 121
    • 0029437313 scopus 로고    scopus 로고
    • Gene therapy and HIV disease
    • MA Jacobson (eds) Marcel Dekker, Inc. New York, Basel, Hong Kong
    • Poesschla EM and Wong-Staal F. Gene therapy and HIV disease In:AIDS Clinical Review 1995/1996 P Wolberding. MA Jacobson (eds) pp 1-28, 1996. Marcel Dekker, Inc. New York, Basel, Hong Kong.
    • (1996) AIDS Clinical Review 1995/1996 P Wolberding , pp. 1-28
    • Poesschla, E.M.1    Wong-Staal, F.2
  • 123
    • 0028354996 scopus 로고
    • Gene therapy for infectious diseases: The AIDS model
    • Gilboa E and Smith C. Gene therapy for infectious diseases: the AIDS model. Trends Genetics 1994; 10:139-144.
    • (1994) Trends Genetics , vol.10 , pp. 139-144
    • Gilboa, E.1    Smith, C.2
  • 124
    • 0026003623 scopus 로고
    • Inhibition of HIV-1 replication in human T cells stably expressing antisense RNA
    • Sczakiel G and Pawlita M,. Inhibition of HIV-1 replication in human T cells stably expressing antisense RNA. J Virol 1991; 65:468-472.
    • (1991) J Virol , vol.65 , pp. 468-472
    • Sczakiel, G.1    Pawlita, M.2
  • 125
    • 0026073759 scopus 로고
    • Inhibition of heterologous strains of HIV by antisense RNA
    • Rhodes A and James W. Inhibition of heterologous strains of HIV by antisense RNA. AIDS 1991; 5:145-151.
    • (1991) AIDS , vol.5 , pp. 145-151
    • Rhodes, A.1    James, W.2
  • 126
    • 0030856993 scopus 로고    scopus 로고
    • Intracellular inhibition of HIV-1 replication using a dual protein- And RNA-based strategy
    • Duan L, Zhu M, Ozaki I, Zhang H, Wei DL and Pomerantz RJ. Intracellular inhibition of HIV-1 replication using a dual protein-and RNA-based strategy. Gene Ther 1997; 4:533-543.
    • (1997) Gene Ther , vol.4 , pp. 533-543
    • Duan, L.1    Zhu, M.2    Ozaki, I.3    Zhang, H.4    Wei, D.L.5    Pomerantz, R.J.6
  • 127
    • 0030710990 scopus 로고    scopus 로고
    • Inhibition of FIV replication by a ribozyme that targets the Rev response element
    • Mergia A, Blackwell J and Chari S. Inhibition of FIV replication by a ribozyme that targets the Rev response element AIDS Res Hum Retroviruses 1997; 13:1333-1338.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 1333-1338
    • Mergia, A.1    Blackwell, J.2    Chari, S.3
  • 128
    • 0026651086 scopus 로고
    • Small catalytic RNAs
    • Symonds RH. Small catalytic RNAs. Ann Rev Biochem 1992; 61:641-671.
    • (1992) Ann Rev Biochem , vol.61 , pp. 641-671
    • Symonds, R.H.1
  • 129
    • 0027257259 scopus 로고
    • Quantitative evaluation of intracellular sense:Antisense RNA hybrid duplexes
    • Wang S, Dolnick B. Quantitative evaluation of intracellular sense:antisense RNA hybrid duplexes. Nucleic Acids Res 1993; 21:4383-4391.
    • (1993) Nucleic Acids Res , vol.21 , pp. 4383-4391
    • Wang, S.1    Dolnick, B.2
  • 130
    • 0024590979 scopus 로고
    • Mutational analysis of human immuodeficiency virus type 1 protease suggests functional homology with aspartic proteinases
    • Loeb DD, Hutchison CA, Edgell MH, farmerie WG and Swanstrom R. Mutational analysis of human immuodeficiency virus type 1 protease suggests functional homology with aspartic proteinases. J Virol 1989; 63:111-121.
    • (1989) J Virol , vol.63 , pp. 111-121
    • Loeb, D.D.1    Hutchison, C.A.2    Edgell, M.H.3    Farmerie, W.G.4    Swanstrom, R.5
  • 131
    • 0342394457 scopus 로고
    • Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1
    • Gottinger HG, Sodroski JG and Haseltine WA. Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1. Proc Natl Acad Sci 1989; 86:5781-5785.
    • (1989) Proc Natl Acad Sci , vol.86 , pp. 5781-5785
    • Gottinger, H.G.1    Sodroski, J.G.2    Haseltine, W.A.3
  • 132
    • 0030578987 scopus 로고    scopus 로고
    • The HIV proteinase- A target for antiviral agents
    • Grinde B and Jonassen TO. The HIV proteinase-a target for antiviral agents. Tidsskr Nor Largeforen 1996; 116:2908-2911.
    • (1996) Tidsskr Nor Largeforen , vol.116 , pp. 2908-2911
    • Grinde, B.1    Jonassen, T.O.2
  • 133
    • 8244248789 scopus 로고    scopus 로고
    • Protease inhibitors: A therapeutic breakthrough for the treatment of patients with human immunodeficiency virus
    • Lewis JS 2nd, Terriff CM, Coulston DR and Garrison MW. Protease inhibitors: a therapeutic breakthrough for the treatment of patients with human immunodeficiency virus. Clin ther 1997; 12:187-214.
    • (1997) Clin Ther , vol.12 , pp. 187-214
    • Lewis II, J.S.1    Terriff, C.M.2    Coulston, D.R.3    Garrison, M.W.4
  • 134
    • 0027413508 scopus 로고
    • HIV protease inhibitors: Their anti-HIV activity and potential role in treatment
    • Robins T and Plattner J. HIV protease inhibitors: their anti-HIV activity and potential role in treatment. J Acquir Immune Defic Syndr 1993; 6:162-170.
    • (1993) J Acquir Immune Defic Syndr , vol.6 , pp. 162-170
    • Robins, T.1    Plattner, J.2
  • 135
    • 0025169561 scopus 로고
    • An inhibitor of the protease blocks maturation of human and siamin immunodeficiency viruses and spread of infection
    • Ashorn P, McQuade TJ, Thaisrivongs S, Tomasselli AG, Tarpley WG and Moss B. An inhibitor of the protease blocks maturation of human and siamin immunodeficiency viruses and spread of infection. Proc Natl Acad Sci USA 1990; 87:7472-7476.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 7472-7476
    • Ashorn, P.1    McQuade, T.J.2    Thaisrivongs, S.3    Tomasselli, A.G.4    Tarpley, W.G.5    Moss, B.6
  • 136
    • 0030895312 scopus 로고    scopus 로고
    • Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations
    • Barry M, Gibbons S, Back D and Mulcahy F. Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations. Clin Pharmacokinet 1997; 32:194-209.
    • (1997) Clin Pharmacokinet , vol.32 , pp. 194-209
    • Barry, M.1    Gibbons, S.2    Back, D.3    Mulcahy, F.4
  • 137
    • 0028951411 scopus 로고
    • Reduction of the in vitro activity of A77003, an inhibitor of human immunodeficiency virus protease, by human serum alpha 1 acid glycoprotein
    • Bilello JA, Bilello PA, Prichard M, Robins T and Drusano GL. Reduction of the in vitro activity of A77003, an inhibitor of human immunodeficiency virus protease, by human serum alpha 1 acid glycoprotein. J Infect Dis 1995; 171:546-551.
    • (1995) J Infect Dis , vol.171 , pp. 546-551
    • Bilello, J.A.1    Bilello, P.A.2    Prichard, M.3    Robins, T.4    Drusano, G.L.5
  • 139
    • 0343323330 scopus 로고    scopus 로고
    • Saquinavir vs Hivid vs combination as treatment for advanced HIV infection in patients discontinuing/unable to take retonavir
    • Vancouver British Columbia
    • Salgo M, Beattie D and Bragman K. Saquinavir vs Hivid vs combination as treatment for advanced HIV infection in patients discontinuing/unable to take retonavir. 11th Conference on AIDS, Vancouver British Columbia 1996, 410.
    • (1996) 11th Conference on AIDS , pp. 410
    • Salgo, M.1    Beattie, D.2    Bragman, K.3
  • 140
    • 0030317870 scopus 로고    scopus 로고
    • The effect of high dose saquinavir on viral load and CD4+ T cell counts in HIV-infected patients
    • Schapiro JM, Winters MA and Stewart F. The effect of high dose saquinavir on viral load and CD4+ T cell counts in HIV-infected patients. Ann Intern Med 1996; 124:1039-1050.
    • (1996) Ann Intern Med , vol.124 , pp. 1039-1050
    • Schapiro, J.M.1    Winters, M.A.2    Stewart, F.3
  • 141
    • 0029644513 scopus 로고
    • Safety and activity of saquinavir in HIV infection
    • Kitchen VS, Skinner C and Ariyoshi K. Safety and activity of saquinavir in HIV infection. Lancet 1995; 345:952-955.
    • (1995) Lancet , vol.345 , pp. 952-955
    • Kitchen, V.S.1    Skinner, C.2    Ariyoshi, K.3
  • 142
    • 0028846165 scopus 로고
    • A short term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease
    • Danner Saa, Carr A and Leonard JM. A short term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease. N Engl J Med 1995; 328:1528-1533.
    • (1995) N Engl J Med , vol.328 , pp. 1528-1533
    • Danner, S.1    Carr, A.2    Leonard, J.M.3
  • 143
    • 0029563673 scopus 로고
    • Treatment with lamivudine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4+ cells per cubic millimeter
    • Eron JJ. Benoit SL and Jemsek J. Treatment with lamivudine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4+ cells per cubic millimeter. N Engl J Med 1995; 333:1662-1669.
    • (1995) N Engl J Med , vol.333 , pp. 1662-1669
    • Eron, J.J.1    Benoit, S.L.2    Jemsek, J.3
  • 145
    • 0030032764 scopus 로고    scopus 로고
    • Preclinical pharmacokinetics and distribution to tissue of AG 1343, an inhibitor of human immunodeficiency virus type 1 protease
    • Shetty BV, Kosa MB and Khalil DA. Preclinical pharmacokinetics and distribution to tissue of AG 1343, an inhibitor of human immunodeficiency virus type 1 protease. Antimicrob Agents Chemother 1996; 40:110-114.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 110-114
    • Shetty, B.V.1    Kosa, M.B.2    Khalil, D.A.3
  • 146
    • 0345569340 scopus 로고    scopus 로고
    • A randomized phase II study of viracept, a novel HIV protease inhibitor, used in combination with stavudine (d4T) vs stavudine alone
    • British Columbia
    • Gathe J Jr, Bukhardt B, Howley P, Conant M, Peterkin J and Chapman S. A randomized phase II study of viracept, a novel HIV protease inhibitor, used in combination with stavudine (d4T) vs stavudine alone. 4th international Conference on AIDS, British Columbia 1996, 413.
    • (1996) 4th International Conference on AIDS , pp. 413
    • Gathe Jr., J.1    Bukhardt, B.2    Howley, P.3    Conant, M.4    Peterkin, J.5    Chapman, S.6
  • 148
    • 0030629262 scopus 로고    scopus 로고
    • Mechanism of neuronal damage in AIDS
    • Nagashima K. Mechanism of neuronal damage in AIDS. Hokkaido Igaku Zasshi 1997; 72:37-41.
    • (1997) Hokkaido Igaku Zasshi , vol.72 , pp. 37-41
    • Nagashima, K.1
  • 153
    • 2442740404 scopus 로고
    • The efficacy of inosine pranobex in preventing the acquired immunodeficiency syndrome in patients with human immunodeficiency virus infection
    • Pedersen C, Sandstorm E, Petersen CS, Norkrons G and Gerstft J. The efficacy of inosine pranobex in preventing the acquired immunodeficiency syndrome in patients with human immunodeficiency virus infection. N Engl J Med 1990; 168:1111-1125.
    • (1990) N Engl J Med , vol.168 , pp. 1111-1125
    • Pedersen, C.1    Sandstorm, E.2    Petersen, C.S.3    Norkrons, G.4    Gerstft, J.5
  • 154
    • 0025844784 scopus 로고
    • Dithiocarb sodium (diethyldithiocarbamate) therapy in patients with symptomatic HIV infection and AIDS
    • Hersch E, Brewton G, Abrom D, Bartlett J and Galpin J. Dithiocarb sodium (diethyldithiocarbamate) therapy in patients with symptomatic HIV infection and AIDS. J Am Med Assoc 1991; 265:1538-1544.
    • (1991) J Am Med Assoc , vol.265 , pp. 1538-1544
    • Hersch, E.1    Brewton, G.2    Abrom, D.3    Bartlett, J.4    Galpin, J.5
  • 155
    • 0030047263 scopus 로고    scopus 로고
    • Naturin: A potent bio-immunomodifier in experimental studies and clinical trials
    • Shen RN, Lu L, Jia XQ, Wong ML and Kaiser HE. Naturin: a potent bio-immunomodifier in experimental studies and clinical trials. In vivo 1996; 20:201-209.
    • (1996) In Vivo , vol.20 , pp. 201-209
    • Shen, R.N.1    Lu, L.2    Jia, X.Q.3    Wong, M.L.4    Kaiser, H.E.5
  • 156
    • 0030935802 scopus 로고    scopus 로고
    • British HIV association guidelines for antiretroviral treatment of HIV seropositive individual
    • BHIV Guidelines Coordinating Committee. British HIV association guidelines for antiretroviral treatment of HIV seropositive individual. Lancet 1997; 349:1086-1092.
    • (1997) Lancet , vol.349 , pp. 1086-1092
  • 157
    • 0030762445 scopus 로고    scopus 로고
    • Preventing opportunistic infections in persons infected with HIV: 1997 Guidelines
    • Kaplan JE, Masseur H, Jaffe HW and Holmes KK. Preventing opportunistic infections in persons infected with HIV: 1997 Guidelines JAMA 1997; 278:337-338.
    • (1997) JAMA , vol.278 , pp. 337-338
    • Kaplan, J.E.1    Masseur, H.2    Jaffe, H.W.3    Holmes, K.K.4
  • 158
    • 0031037171 scopus 로고    scopus 로고
    • Drug treatment of HIV-related opportunistic infections
    • Klepser ME and Klepser TB. Drug treatment of HIV-related opportunistic infections. Drugs 1997; 53:40-73.
    • (1997) Drugs , vol.53 , pp. 40-73
    • Klepser, M.E.1    Klepser, T.B.2
  • 159
    • 0030787518 scopus 로고    scopus 로고
    • Candidate antiretroviral agents for use in postexposure prophylaxis
    • Saag MS. Candidate antiretroviral agents for use in postexposure prophylaxis. Am J Med 1997; 102:25-31.
    • (1997) Am J Med , vol.102 , pp. 25-31
    • Saag, M.S.1
  • 160
    • 0029690201 scopus 로고    scopus 로고
    • Overview of HIV vaccine development
    • Bolognesi DP. Overview of HIV vaccine development Antibiot Chemother 1996; 48:63-67.
    • (1996) Antibiot Chemother , vol.48 , pp. 63-67
    • Bolognesi, D.P.1
  • 162
    • 0031575965 scopus 로고    scopus 로고
    • Getting the vaccine strategy right in HIV-1 disease
    • Rowe PM. Getting the vaccine strategy right in HIV-1 disease. Lancet 1997; 349:1454.
    • (1997) Lancet , vol.349 , pp. 1454
    • Rowe, P.M.1
  • 163
    • 0029922593 scopus 로고    scopus 로고
    • Progress and challenges toward an AIDS vaccine: Brother, can you spare a paradigm?
    • Koff WC and Schultz AM. Progress and challenges toward an AIDS vaccine: Brother, can you spare a paradigm? J Clin Immunol 1996; 16:127-133.
    • (1996) J Clin Immunol , vol.16 , pp. 127-133
    • Koff, W.C.1    Schultz, A.M.2
  • 164
    • 0030915812 scopus 로고    scopus 로고
    • A deadline for an AIDS vaccine
    • Lawler A and Cohen J. A deadline for an AIDS vaccine. Science 1997; 276:1184-1185.
    • (1997) Science , vol.276 , pp. 1184-1185
    • Lawler, A.1    Cohen, J.2
  • 166
    • 0031064870 scopus 로고    scopus 로고
    • A vaccine against AIDS. Hope at last
    • Wagner L. A vaccine against AIDS. Hope at last. Tenn Nurse 1997; 60:19-21.
    • (1997) Tenn Nurse , vol.60 , pp. 19-21
    • Wagner, L.1
  • 167
    • 0030842457 scopus 로고    scopus 로고
    • Design of peptide and porypeptide vaccines
    • Ben Yedidia T and Arnon R. Design of peptide and porypeptide vaccines. Curr Opin Biotechnol 1997; 8:442-228.
    • (1997) Curr Opin Biotechnol , vol.8 , pp. 442-1228
    • Ben Yedidia, T.1    Arnon, R.2
  • 168
    • 0030987291 scopus 로고    scopus 로고
    • HIV type 1 coreceptors, neutralisation serotypes, and vaccine development
    • Moore J and Trkola A. HIV type 1 coreceptors, neutralisation serotypes, and vaccine development AIDS Res Hum Retroviruses 1997; 13:733-736.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 733-736
    • Moore, J.1    Trkola, A.2
  • 169
    • 0031579072 scopus 로고    scopus 로고
    • Highlights from the University of California San Diego Center for AIDS Research
    • Wong-Staal. Highlights from the University of California San Diego Center for AIDS Research. AIDS Res Hum Retroviruses 1997; 13:733-736.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 733-736
    • Wong-Staal1
  • 170
    • 0030481435 scopus 로고    scopus 로고
    • New scientific developments towards an AIDS vaccine: Report on a workshop organized by EU program EVa entitled Novel approaches to AIDS vaccine development held at the Institute Pasteur, Paris 1995
    • Oxford JS and Jeffs SA. New scientific developments towards an AIDS vaccine: report on a workshop organized by EU program EVA entitled Novel approaches to AIDS vaccine development held at the Institute Pasteur, Paris 1995. Vaccine 1996; 14:1712-1717.
    • (1996) Vaccine , vol.14 , pp. 1712-1717
    • Oxford, J.S.1    Jeffs, S.A.2
  • 171
    • 0030740987 scopus 로고    scopus 로고
    • HIV genetic variation: Clinical importance
    • Lever AML. HIV genetic variation: Clinical importance. J Infection 1997; 34:195-199.
    • (1997) J Infection , vol.34 , pp. 195-199
    • Lever, A.M.L.1
  • 172
    • 0028988479 scopus 로고    scopus 로고
    • Pol Gene quasispecies of human immunodeficiency virus: Mutations associated with drug resistance in virus from patients undergoing no drug therapy
    • Najera I, Holguin A and Quinones-Mateu ME. pol Gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy. J Virol 69:23-31, 1996.
    • (1996) J Virol , vol.69 , pp. 23-31
    • Najera, I.1    Holguin, A.2    Quinones-Mateu, M.E.3
  • 173
    • 0029798237 scopus 로고
    • Nevirapine-resistant human immunodeficiency virus: Kinetics of replication and estimated prevalence in untreated patients
    • Havlir DV, Eastman S, Gamst A and Richman DD. Nevirapine-resistant human immunodeficiency virus: kinetics of replication and estimated prevalence in untreated patients. J Virol 1994; 70:7894-7899.
    • (1994) J Virol , vol.70 , pp. 7894-7899
    • Havlir, D.V.1    Eastman, S.2    Gamst, A.3    Richman, D.D.4
  • 174
    • 0030065565 scopus 로고    scopus 로고
    • Resistance of human immunodeficiency virus type 1 to protease inhibitors: Selection of resistance in the presence and absence of the drug
    • Borman AM, Paulous S and Clavel F. Resistance of human immunodeficiency virus type 1 to protease inhibitors: selection of resistance in the presence and absence of the drug. J Gen Virol 1996; 77:419-426.
    • (1996) J Gen Virol , vol.77 , pp. 419-426
    • Borman, A.M.1    Paulous, S.2    Clavel, F.3
  • 175
    • 0027957791 scopus 로고
    • Nevirapine resistance mutations of human immunodeficiency virus type-1 selected drug therapy
    • Richman DD, Havlir D, Corbeil J. Nevirapine resistance mutations of human immunodeficiency virus type-1 selected drug therapy. J Virol 1994, 68: 1660-1666.
    • (1994) J Virol , vol.68 , pp. 1660-1666
    • Richman, D.D.1    Havlir, D.2    Corbeil, J.3
  • 176
    • 15444377672 scopus 로고    scopus 로고
    • Ordered accumulation of mutations in HIV protease confers resistance to ritonavir
    • Molla A, Korneyeva M and Gao Q. Ordered accumulation of mutations in HIV protease confers resistance to ritonavir. Nat Med 1996; 2:760-766.
    • (1996) Nat Med , vol.2 , pp. 760-766
    • Molla, A.1    Korneyeva, M.2    Gao, Q.3
  • 177
    • 10344263394 scopus 로고    scopus 로고
    • Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor
    • Coudra JH, Holder DJ and Schleif WA. Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol 1996; 70:8270-8276.
    • (1996) J Virol , vol.70 , pp. 8270-8276
    • Coudra, J.H.1    Holder, D.J.2    Schleif, W.A.3
  • 178
    • 0030788884 scopus 로고    scopus 로고
    • Prevalence and incidence of resistance to zidovudine and other antiretroviral drugs
    • Mayers DL. Prevalence and incidence of resistance to zidovudine and other antiretroviral drugs. Am J Med 1997 102:70-75.
    • (1997) Am J Med , vol.102 , pp. 70-75
    • Mayers, D.L.1
  • 179
    • 0029614884 scopus 로고
    • Drug resistance patterns of saquinavir and other HIV proteinase inhibitors
    • Roberts NA. Drug resistance patterns of saquinavir and other HIV proteinase inhibitors. AIDS 1995; 9:S 27-S 32.
    • (1995) AIDS , vol.9
    • Roberts, N.A.1
  • 181
    • 0025991478 scopus 로고
    • Two-drug combinations of zidovudine, didanosine and recombinant interferon-alpha a inhibited replication of zidovudine-resistant human immunodeficiency virus type-1 synergistically in vitro
    • Johnson VA, Merrill DP and Videler JA. Two-drug combinations of zidovudine, didanosine and recombinant interferon-alpha A inhibited replication of zidovudine-resistant human immunodeficiency virus type-1 synergistically in vitro. J Infect Dis 1991; 164:646-655.
    • (1991) J Infect Dis , vol.164 , pp. 646-655
    • Johnson, V.A.1    Merrill, D.P.2    Videler, J.A.3
  • 182
    • 0029007143 scopus 로고
    • Drug resistance and heterogeneous long-term virologic responses of human immunodeficiency virus type-1-infected subjects to zidovudine and didanosine combination therapy
    • The AIDS Clinical Trials Group 143 Virology Team
    • Shafer RW, Iversen AK and Winters MA. Drug resistance and heterogeneous long-term virologic responses of human immunodeficiency virus type-1-infected subjects to zidovudine and didanosine combination therapy. The AIDS Clinical Trials Group 143 Virology Team. J Infect Dis 1995; 172:70-78.
    • (1995) J Infect Dis , vol.172 , pp. 70-78
    • Shafer, R.W.1    Iversen, A.K.2    Winters, M.A.3
  • 183
    • 0030042695 scopus 로고    scopus 로고
    • Lamivudine or stavudine in two and three drug combinations against human immunodeficiency virus type-1 replication in vitro
    • Merrill DP, Moonis M, Chou TC and Hirsch MS. Lamivudine or stavudine in two and three drug combinations against human immunodeficiency virus type-1 replication in vitro. J Infect Dis 1996; 173:335-364.
    • (1996) J Infect Dis , vol.173 , pp. 335-364
    • Merrill, D.P.1    Moonis, M.2    Chou, T.C.3    Hirsch, M.S.4
  • 184
    • 2442738894 scopus 로고    scopus 로고
    • A phase II randomized study of the virologic and immunologic effects of d4T versus DDI versus zidovudine plus d4T versus zidovudine plus DDI in HIV infected patients with CD4 cell counts between 300-600 cubic millimeter and greater than 12 weeks zidovudine experience
    • ACTG 290 Protocol Team. A phase II randomized study of the virologic and immunologic effects of d4T versus DDI versus zidovudine plus d4T versus zidovudine plus DDI in HIV infected patients with CD4 cell counts between 300-600 cubic millimeter and greater than 12 weeks zidovudine experience. ACTG 290 Interim Review Results. 1996.
    • (1996) ACTG 290 Interim Review Results
  • 186
    • 0025287373 scopus 로고
    • Toxicity of combined ganciclovir and zidovudine for cytomegalovirus disease associated with AIDS
    • Hochster H, Dieterich D and Bozzette S. Toxicity of combined ganciclovir and zidovudine for cytomegalovirus disease associated with AIDS. Ann Intern Med 1990; 113:111-117.
    • (1990) Ann Intern Med , vol.113 , pp. 111-117
    • Hochster, H.1    Dieterich, D.2    Bozzette, S.3
  • 188
    • 0023837875 scopus 로고
    • Phase I studies of 2′,3′-dideoxycytidine in severe human immunodeficiency virus infection as a single and alternating with zidovudine (AZT)
    • Yarchoan R, Perno CF, Thomas RV, Klecker RW, Allain JP and Wills RJ. Phase I studies of 2′,3′-dideoxycytidine in severe human immunodeficiency virus infection as a single and alternating with zidovudine (AZT). Lancet 1988; 1:76-81.
    • (1988) Lancet , vol.1 , pp. 76-81
    • Yarchoan, R.1    Perno, C.F.2    Thomas, R.V.3    Klecker, R.W.4    Allain, J.P.5    Wills, R.J.6
  • 189
    • 0028010789 scopus 로고
    • A randomized pilot study of alternating or simultaneous zidovudine and didanosine therapy in patients with symptomatic human immunodeficiency virus infection
    • Yarchoan R, Lietzau JA and Nguyen BY. A randomized pilot study of alternating or simultaneous zidovudine and didanosine therapy in patients with symptomatic human immunodeficiency virus infection. J Infect Dis 1994; 169:9-17.
    • (1994) J Infect Dis , vol.169 , pp. 9-17
    • Yarchoan, R.1    Lietzau, J.A.2    Nguyen, B.Y.3
  • 192
    • 0031007534 scopus 로고    scopus 로고
    • British HIV association guidelines for antiretroviral treatment of HIV seropositive individuals
    • Carey PB, Lloyd J and Timmins D. British HIV association guidelines for antiretroviral treatment of HIV seropositive individuals. Lancet 1997; 349:1837.
    • (1997) Lancet , vol.349 , pp. 1837
    • Carey, P.B.1    Lloyd, J.2    Timmins, D.3
  • 193
    • 0030905027 scopus 로고    scopus 로고
    • Baseline HIV type I load predicts the long-term clinical outcome of infected patients. The 'positive feedback theory'
    • Briant L and Devaux C. Baseline HIV type I load predicts the long-term clinical outcome of infected patients. The 'positive feedback theory'. Immunol Lett 1997; 35:123-125.
    • (1997) Immunol Lett , vol.35 , pp. 123-125
    • Briant, L.1    Devaux, C.2
  • 194
    • 0030933549 scopus 로고    scopus 로고
    • The eleventh international conference on AIDS: Cautious celebration in Vancouver
    • Gibaldi M. The eleventh international conference on AIDS: cautious celebration in Vancouver. J Clin Pharmacol 1997; 37:20-24.
    • (1997) J Clin Pharmacol , vol.37 , pp. 20-24
    • Gibaldi, M.1
  • 195
    • 0030971002 scopus 로고    scopus 로고
    • Complementary AIDS therapies: The good, the bad and the ugly
    • Ernst E. Complementary AIDS therapies: the good, the bad and the ugly. Int J STD AIDS 1997; 8:281-285.
    • (1997) Int J STD AIDS , vol.8 , pp. 281-285
    • Ernst, E.1
  • 196
    • 0030925766 scopus 로고    scopus 로고
    • Guidelines for managing HIV infection
    • DeCock KM. Guidelines for managing HIV infection. BMJ 1997; 315:1-2.
    • (1997) BMJ , vol.315 , pp. 1-2
    • DeCock, K.M.1
  • 198
    • 0030934493 scopus 로고    scopus 로고
    • HIV infection: Future perspective for a so-called fatal disease?
    • von Overbeck J and Iten A. HIV infection: future perspective for a so-called fatal disease? Schweiz Med Wochenschr 1997; 127:521-527.
    • (1997) Schweiz Med Wochenschr , vol.127 , pp. 521-527
    • Von Overbeck, J.1    Iten, A.2
  • 199
    • 0029840615 scopus 로고    scopus 로고
    • The past as preclude to the future: History, status and future of antiviral drugs
    • Whitley RJ. The past as preclude to the future: history, status and future of antiviral drugs. Ann Pharmacother 1996, 30:967-971.
    • (1996) Ann Pharmacother , vol.30 , pp. 967-971
    • Whitley, R.J.1


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