Conference summary: Preliminary evidence for partial restoration of immune function in HIV type 1 infection with potent antiretroviral therapies: Clues from the fourth conference on retroviruses and opportunistic diseases

AIDS Research and Human Retroviruses

Volumn 13, Issue 10, 1997, Pages 815-818

  Schnittman, Steven M ^a   Fox, Lawrence ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; CD38 ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; LAMIVUDINE; RITONAVIR; SAQUINAVIR; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; VIRUS RNA; ZIDOVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

CLINICAL TRIAL; CONFERENCE PAPER; DRUG EFFICACY; HELPER CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; IMMUNOPATHOGENESIS; PRIORITY JOURNAL; VIRUS PATHOGENESIS; VIRUS REPLICATION; CD4+ T LYMPHOCYTE; DRUG EFFECT; IMMUNE SYSTEM; IMMUNOLOGY; T LYMPHOCYTE SUBPOPULATION;

ANTI-HIV AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CLINICAL TRIALS; HIV INFECTIONS; HIV-1; HUMANS; IMMUNE SYSTEM; T-LYMPHOCYTE SUBSETS;

EID: 0031183153     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.1997.13.815     Document Type: Conference Paper

References (13)

1. Ho DD, Neumann AU, Perelson AS, Chen W, Leonard JM, and Markowitz M: Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature (London) 1995;373:123-126.
2. Wei X, Ghosh SK, Taylor ME, Johnson VA, Emini EA, Deutsch P, Lifson JD, Bonhoeffer S, Nowak MA, Hahn BH, et al.: Viral dynamics in human immunodeficiency virus type 1 infection. Nature (London) 1995;373:117-122.
3. Fauci AS: Multifactorial nature of human immunodeficiency virus disease: Implications for therapy. Science 1993;262:1011-1018.
4. Clerici M and Shearer GM: The Th1-Th2 hypothesis of HIV infection: New insight. Immunol Today 1994;15:575-581.
5. Little S, Havlir D, Richman D, McLean A, Spina C: Dynamics of T lymphocytes in primary HIV infection. Abstract 39 in 4th Conference on Retroviruses and Opportunistic Infections, January 22-26, 1997, Washington, D.C.
6. Graziosi C, Soudeyns H, Welbon CC, Pantaleo G, Fauci AS: Rapid depletion of virus specific T cell clones during primary HIV-1 but not EBV infection. Implications for escape from the immune response. Abstract LB17 in 4th Conference on Retroviruses and Opportunistic Infections. January 22-26, 1997, Washington, D.C.
7. Giorgi JV, Effros RB, and West MD: Immunologic exhaustion in CD8+ T lymphocytes in HIV disease. Abstract 385 in 4th Conference on Retroviruses and Opportunistic Infections, January 22-26, 1997, Washington, D.C.
8. Lederman M, Connick E, Landay A, Kessler H, Kuritzkes D, St. Clair M., Fox L. Heath-Chiozzi M, Rousseau F, and Spritzler J: Partial immune reconstitution after 12 weeks of HAART (AZT, 3TC, Ritonavir). Preliminary results of ACTG 315. Abstract LB13 in 4th Conference on Retroviruses and Opportunistic Infections, January 22-26, 1997, Washington, D.C.
9. Angel JB, Parato K, Kumar A, Filion LG, Diaz-Mitoma F, Pham B, Sun E, and Leonard J: Rapid improvement in cell mediated immune function with initiation of ritonavir plus saquinavir in HIV immune deficiency. Abstract 33 in 4th Conference on Retroviruses and Opportunistic Infections, January 22-26, 1997, Washington, D.C.
10. Autran B, Mathez D, Carcelain G, Blanc C, Debre P, and Leibowitch J: Dynamics of the CD4 T helper cell subset reconstitution after combined anti-retroviral therapies. Abstract 34 in 4th Conference on Retroviruses and Opportunistic Infections, January 22-26, 1997, Washington, D.C.
11. Connors M, Kovacs JA, Gea-Banacloche J C, Weiskopf E, Falloon J, Baseler M, Stevens R, and Lane HC: HIV induces changes in CD4+ T cell phenotype and repertoire that are not immediately restored by antiviral or immune-based therapies. Abstract 369 in 4th Conference on Retroviruses and Opportunistic Infections, January 22-26, 1997, Washington, D.C.
12. Markowitz M, Cao Y, Vesanen M, Talal A, Nixon D, Hurley A, O'Donovan R, Racz P, Tenner-Racz K, and Ho DD: Recent HIV infection treated with AZT, 3TC, and a potent protease inhibitor. Abstract LB8 in 4th Conference on Retroviruses and Opportunistic Infections, January 22-26, 1997, Washington, D.C.
13. Mackall CL, Fleisher TA, Brown MR, Andrich MP, Chen CC, Feuerstein IM, Horowitz ME, Magrath IT, Shad AT, Steinberg SM, Wexler LH, and Gress RE: Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy. New Engl J Med 1995;332:143-149.