메뉴 건너뛰기




Volumn 116, Issue 24, 1996, Pages 2908-2911

The HIV proteinase - A target for antiviral therapy;HIVS PROTEINASE - ET MAAL FOR ANTIVIRALE MIDLER

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; INDINAVIR; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; ZALCITABINE; ZIDOVUDINE; PROTEINASE;

EID: 0030578987     PISSN: 00292001     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey
Times cited : (4)

References (20)
  • 1
    • 0025017237 scopus 로고
    • Viral proteinases: Weakness in strength
    • Kay J, Dunn BM. Viral proteinases: weakness in strength. Biochim Biophys Acta 1990; 1048: 1-18.
    • (1990) Biochim Biophys Acta , vol.1048 , pp. 1-18
    • Kay, J.1    Dunn, B.M.2
  • 2
    • 0028986487 scopus 로고
    • Targeting HIV-1 protease: A test of drugdesign methodologies
    • West ML, Fairlie DP. Targeting HIV-1 protease: a test of drugdesign methodologies. TIPS 1995; 16: 67-75.
    • (1995) TIPS , vol.16 , pp. 67-75
    • West, M.L.1    Fairlie, D.P.2
  • 3
    • 0024599149 scopus 로고
    • Retroviral proteases: First glimpses at the anatomy of a processing machine
    • Skalka AM. Retroviral proteases: first glimpses at the anatomy of a processing machine. Cell 1989; 56: 911-3.
    • (1989) Cell , vol.56 , pp. 911-913
    • Skalka, A.M.1
  • 4
    • 0024102469 scopus 로고
    • The molecular biology of the AIDS virus
    • Haseltine WA, Wong-Staal F. The molecular biology of the AIDS virus. Sci Am 1988 259: 52-8.
    • (1988) Sci Am , vol.259 , pp. 52-58
    • Haseltine, W.A.1    Wong-Staal, F.2
  • 6
    • 0342394457 scopus 로고
    • Role of capsid precursor processing and myristylation in morphogenesis and infectivity of human immunodeficincy virus type 1
    • Gottlinger HG, Sodroski JG, Haseltine WA. Role of capsid precursor processing and myristylation in morphogenesis and infectivity of human immunodeficincy virus type 1. Proc Natl Acad Sci USA 1989; 86: 5781-5.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5781-5785
    • Gottlinger, H.G.1    Sodroski, J.G.2    Haseltine, W.A.3
  • 7
    • 0024412506 scopus 로고
    • Conserved folding in retroviral proteases: Crystal structure of a synthetic HIV-1 protease
    • Wlodawer A, Miller M, Jaskolski M, Sathyanarayana BK, Baldwin E, Weber IT et al. Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease. Science 1989; 245: 616-21.
    • (1989) Science , vol.245 , pp. 616-621
    • Wlodawer, A.1    Miller, M.2    Jaskolski, M.3    Sathyanarayana, B.K.4    Baldwin, E.5    Weber, I.T.6
  • 8
    • 0024363183 scopus 로고
    • The proteinase inhibitor pepstatin A inhibits formation of reverse transcriptase in H9 cells infected with human immunodefficiency virus 1
    • Grinde B, Hungnes O, Tjøtta E. The proteinase inhibitor pepstatin A inhibits formation of reverse transcriptase in H9 cells infected with human immunodefficiency virus 1. AIDS Res Human Retro 1989; 5: 269-74.
    • (1989) AIDS Res Human Retro , vol.5 , pp. 269-274
    • Grinde, B.1    Hungnes, O.2    Tjøtta, E.3
  • 9
    • 0028971801 scopus 로고
    • Progress in anti-HIV structure-based drug design
    • Gait MJ, Karn J. Progress in anti-HIV structure-based drug design. Tibtech 1995; 13: 430-8.
    • (1995) Tibtech , vol.13 , pp. 430-438
    • Gait, M.J.1    Karn, J.2
  • 10
    • 0028047009 scopus 로고
    • Rational drug design: The proteinase inhibitors
    • Wlodawer A. Rational drug design: the proteinase inhibitors. Pharmacotherapy 1994; 14 (suppl): 9-20.
    • (1994) Pharmacotherapy , vol.14 , Issue.SUPPL. , pp. 9-20
    • Wlodawer, A.1
  • 12
    • 0026778802 scopus 로고
    • Analysis of substrate interactions of the Rous sarcoma virus wild type and mutant proteases and human immunodeficiency virus-1 protease using a set of systematically altered peptide substrates
    • Grinde B, Cameron CE, Leis J, Weber I, Wlodawer A, Burstein H et al. Analysis of substrate interactions of the Rous sarcoma virus wild type and mutant proteases and human immunodeficiency virus-1 protease using a set of systematically altered peptide substrates. J Biol Chem 1992; 267: 9491-8.
    • (1992) J Biol Chem , vol.267 , pp. 9491-9498
    • Grinde, B.1    Cameron, C.E.2    Leis, J.3    Weber, I.4    Wlodawer, A.5    Burstein, H.6
  • 13
    • 0027082783 scopus 로고
    • Mechanism of inhibition of the retroviral protease by a Rous sarcoma virus peptide substrate representing the cleavage site between the gag p2 and p10 proteins
    • Cameron CE, Grinde B, Jentoft J, Leis J, Weber I, Copeland TD et al. Mechanism of inhibition of the retroviral protease by a Rous sarcoma virus peptide substrate representing the cleavage site between the gag p2 and p10 proteins. J Biol Chem 1992; 267: 23735-41.
    • (1992) J Biol Chem , vol.267 , pp. 23735-23741
    • Cameron, C.E.1    Grinde, B.2    Jentoft, J.3    Leis, J.4    Weber, I.5    Copeland, T.D.6
  • 14
    • 0027232325 scopus 로고
    • Comparison of the substrate-binding pockets of the Rous sarcoma virus and human immunodeficiency virus type 1 proteases
    • Cameron CE, Grinde B, Jacques P, Jentoft J, Leis J, Wlodawer A et al. Comparison of the substrate-binding pockets of the Rous sarcoma virus and human immunodeficiency virus type 1 proteases. J Biol Chem 1993; 268: 11711-20.
    • (1993) J Biol Chem , vol.268 , pp. 11711-11720
    • Cameron, C.E.1    Grinde, B.2    Jacques, P.3    Jentoft, J.4    Leis, J.5    Wlodawer, A.6
  • 16
    • 0030576119 scopus 로고    scopus 로고
    • Protease inhibitors fly through FDA
    • Barnett AA. Protease inhibitors fly through FDA. Lancet 1996; 347: 678.
    • (1996) Lancet , vol.347 , pp. 678
    • Barnett, A.A.1
  • 17
    • 0028846165 scopus 로고
    • A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease
    • Danner SA, Carr A, Leonard JM, Lehman LM, Guidol F, Gonzales J et al. A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease. N Engl J Med 1995; 333: 1528-33.
    • (1995) N Engl J Med , vol.333 , pp. 1528-1533
    • Danner, S.A.1    Carr, A.2    Leonard, J.M.3    Lehman, L.M.4    Guidol, F.5    Gonzales, J.6
  • 18
    • 0030065565 scopus 로고    scopus 로고
    • Resistance of human immunodeficiency virus type 1 to protease inhibitors: Selection of resistance mutations in the presence and absence of the drug
    • Borman AM, Paulous S, Clavel F. Resistance of human immunodeficiency virus type 1 to protease inhibitors: selection of resistance mutations in the presence and absence of the drug. J Gen Virol 1996; 77: 419-26.
    • (1996) J Gen Virol , vol.77 , pp. 419-426
    • Borman, A.M.1    Paulous, S.2    Clavel, F.3
  • 19
    • 0028962186 scopus 로고
    • Protease uninhibited
    • Richman DD. Protease uninhibited. Nature 1995; 374: 494.
    • (1995) Nature , vol.374 , pp. 494
    • Richman, D.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.