Cardiac and glycemic benefits of troglitazone treatment in NIDDM

Diabetes

Volumn 46, Issue 3, 1997, Pages 433-439

  Ghazzi, Mahmoud N ^a   Perez, Julio E ^b   Antonucci, Tammy K ^a   Driscoll, Joseph H ^a   Huang, Saling M ^a   Faja, Barbara W ^a   Whitcomb, Randall W ^a  

^a PFIZER INC   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLIBENCLAMIDE; ORAL ANTIDIABETIC AGENT; TROGLITAZONE;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR EFFECT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DYSLIPIDEMIA; FEMALE; HUMAN; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPERTENSION; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

EID: 0031054699     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.46.3.433     Document Type: Article

References (28)

1. Whitcomb RW, Saltiel AR: Oncologic, endocrine and metabolic: thiazolidinediones. Exp Opin Invest Drugs 4:1299-1309, 1995
2. Fujiwara T, Yoshioka S, Yoshioka T, Ushiyama I, Horikoshi H: Characterization of new oral antidiabetic agent CS-045. Diabetes 37:1549-1558, 1988
3. Fujiwara T, Yoshioka S, Koike H, Horikoshi H: The antihypertensive effects of CS-045 in obese Zucker rats (Abstract). Diabetes 41 (Suppl. 1):125A, 1992
4. Yoshioka S, Nishino H, Skiraki T, Ikeda K, Koike H, Okuno A, Wada M, Fujiwara T, Horikoshi H: The antihypertensive effects of CS-045 in obese Zucker rats. Metabolism 42:75-80, 1993
5. Ciaraldi TP, Gilmore A, Olefsky J, Goldberg M, Heindenreich KA: In vitro studies on the action of CS-045, a new antidiabetic agent. Metabolism 39:1056-1062, 1990
6. Yoshioka T, Fiyita T, Kanai T, Aizawa Y, Kururnade T, Hasegawa K, Horikoshi H: Studies on hindered phenols and analogues. I. Hypolipidemic and hypoglycemic agents with ability to inhibit lipid peroxidation. J Medicinal Chem 32:421-128, 1989
7. Kuzuya T, Kosaka K, Iwamoto Y, Takebe K, Yamanouchi T, Akanuma Y, Kajinuma H, Doi K: An open trial of a new oral hypoglycemic agent, CS-045, in patients with non-insulin dependent diabetes mellitus. Diabetes 39 (Suppl. 1):106A, 1990
8. Okuno G, Old A, Kawakami F: Clinical effect of a new oral antidiabetic agent CS-045 in diabetic patients with insufficient efficacy of sulfonylureas (Abstract). Diabetes 40 (Suppl. 1):343A, 1991
9. Kuzuya T, Iwamoto Y, Kosaka K, Takebe K, Yamanouchi T, Kasuga M, Kajinuma H, Akanuma Y, Yoshida S, Shigeta Y, Baba S: A pilot clinical trial of a new oral hypoglycemic agent, CS-045, in patients with non-insulin dependent diabetes melutus. Diabetes Res Clin Practice 11:147-154, 1991
10. Shigeta Y, Kobayashi M, Kosaka K, Shimizu N, Kaneko T, Kuzuya T, Akanuma Y: Clinical evaluation of a new oral hypoglycemic agent CS-045 in uncontrolled non-insulin dependent diabetic patients (Abstract). Diabetes 41 (Suppl. 1):76A, 1992
11. Norris R, Valiquett T, Balagtas C: Comparison of troglitazone (CI-991) dosing regimens and placebo in the treatment of patients with NIDDM (Abstract). Diabetes 42 (Suppl. 1):59A, 1993
12. Suter SL, Nolan JJ, Wallace P, Gumbiner B, Olefsky JM: Metabolic effects of a new oral hypoglycemic agent, CS-045, in non-insulin dependent diabetic subjects. Diabetes Care 15:193-203, 1992
13. Mayfleld R, McLean D, Crook D, Buist DP, Gopinath C: CS-045 Toxicity to the cynomolgus monkeys by repeated oral administration for 52 weeks. J Clin Ther Med 9 (Suppl. 3):317-341, 1993
14. Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, GutgeseU H, Reichek N, Sahn D, Schnittger I, Silverman NH, Tajik AJ: Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. J Am Society Echocardiography 2:358-367, 1989
15. Feigenbaum H: Doppler color flow imaging. In Heart Disease Update. Braunwald E, Ed. Philadelphia, Saunders, 1988
16. Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low density lipoprotein cholesterol in plasma without the use of a centrifuge. Clin Chem 18:449-502, 1972
17. Byrd BF III, Wahr D, Wang YS, Bouchard A, Schiller NB: Left ventricular mass and volume/mass ratio determined by two-dimensional echocardiography in normal adults. J Am Coll Cardiol 6:1021-1025, 1985
18. Schiller NB, Skioldebrand CG, Schiller EJ, Mavroudis CC, Silverman NH, Rahimtoola SH, Lipton MJ: Canine left ventricular mass estimation by two-dimensional echocardiography. Circulation 68:210-216, 1983
19. Byrd BF, Finkbeiner W, Bouchard A, Silverman N, Schiller NB: Factors influencing accuracy of two-dimensional echocardiographic left ventricular mass measurement (Abstract). J Am Coll Cardiol 3:515, 1984
20. Zhang F, Sowers JR, Ran JL, Standley Pr, Peuler JD: Effects of pioglitazone on calcium channels in vascular smooth muscle. Hypertension 24:170-175, 1994
21. Stout RW: Insulin and atheroma: 20-yr perspective. Diabetes Care 13:631-654, 1990
22. Olefsky JM, Molina JM: Insulin resistance in man. In Diabetes Mettitus Theory and Practice. Rifkin H, Porte D Jr, Eds. 4th ed. New York, Elsevier, 1990, p.121-153
23. Koskinen P, Viikari J, Irjala K, Kaihola H-L, Seppala P: C-peptide determination in the choice of treatment in diabetes mellitus. Scand J Clin Lab Invest 45:589-597, 1985
24. Haffner SM, Valdez RA, Hazuda HP, Mitchell BD, Morales PA, Stern MP: Prospective analysis of the insulin-resistance syndrome (Syndrome X). Diabetes 41:715-722, 1992
25. Reaven GM: Role of insulin resistance in human diabetes. Diabetes 37:1595-1607, 1988
26. Amri EZ, Bonino F, AlHaud G, Abumarad NA, Grimaldi PA: Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. J Biol Chem 270:2367-2371, 1995
27. Lehmann JN, Moore LB, Smith Oliver TA, Wilkison WO, Willson TM, Kleiwer SA: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator activated receptor γ (PPAKγ). J Biol Chem 270:12953-12956, 1995
28. Nilson EP, Garfinkel AS, Schotz MC: Lipolytic enzymes and plasma lipoprotein metabolism. Annu Rev Biochem 49:667-693, 1980