The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 5, 1997, Pages 1840-1845

  Brown, Kevin D ^a   Ziv, Yael ^b   Sadanandan, Sunanda N ^a   Chessa, Luciana ^c   Collins, Francis S ^a   Shiloh, Yosef ^b   Tagle, Danilo A ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; NUCLEAR PROTEIN; PROTEIN P53; ZINOSTATIN;

ATAXIA TELANGIECTASIA; CELL CYCLE; CONFERENCE PAPER; DNA DAMAGE; GAMMA IRRADIATION; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; LYMPHOBLAST; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ATAXIA; ATAXIA TELANGIECTASIA;

EID: 0031047915     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.5.1840     Document Type: Article

References (46)

1. Sedgwick, R. P. & Boder, E. (1972) in Handbook of Clinical Neurology, eds. Vinken, P. J. & Bruyn, G. W. (North-Holland, Amsterdam), pp. 267-339.
2. Shiloh, Y. (1995) Eur. J. Hum. Genet. 3, 116-138.
3. Swift, M., Morrell, D., Massey, R. B. & Chase, C. L. (1991) New Eng. J. Med. 325, 1831-1836.
4. Easton, D. F. (1994) Int. J. Radiat. Biol. 66, S187-S182.
5. Painter, R. B. & Young, B. R. (1980) Proc. Natl. Acad. Sci. USA 77, 7315-7317.
6. Hartwell, L. M. & Weinert, T. A. (1989) Science 246, 629-634.
7. Kastan, M. B., Zhan, Q., El-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B. & Fornace, A. J. (1992) Cell 71, 587-597.
8. Yin, Y., Tainsky, M. A., Bischoff, F. Z., Strong, L. C. & Wahl, G. M. (1992) Cell 70, 937-948.
9. Livingston, L. R., White, A., Sprouse, J., Livanos, E., Jacks, T. & Tlsty, T. D. (1992) Cell 70, 923-935.
10. Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K. & Elledge, S. J. (1993) Cell 75, 805-816.
11. El-Deiry W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W. & Vogelstein, B. (1993) Cell 75, 817-825.
12. Dulic, V. Kaufmann, W. K., Wilson, S. J., Tlsty, T. D., Lees, E., Harper, J. W., Elledge, S. J. & Reed, S. I. (1994) Cell 76, 1013-1024.
13. Khanna, K. K. & Lavin, M. F. (1993) Oncogene 8, 3307-3312.
14. Canman, C. E., Wolff, A. C., Chen, C.-Y., Fornace, A. J. & Kastan, M. B. (1994) Cancer Res. 54, 5054-5058.
15. Savitsky, K., Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y., et al. (1995) Science 268, 1749-1753.
16. Savitsky, K., Sfez, S., Tagle, D. A., Ziv, Y., Sartiel, A., Collins, F. S., Shiloh, Y. & Rotman, G. (1995) Hum. Mol. Genet. 4, 2025-2032.
17. Zakian, V. A. (1995) Cell 82, 685-687.
18. Abrams, H. D., Rohrschneider, L. R. & Eisenmann, R. N. (1982) Cell 29, 427-439.
19. Brown, K. D., Coulson, R. M. R., Yen, T. J. & Cleveland, D. W. (1994) J. Cell Biol. 125, 1303-1312.
20. Laemmli, U. K. (1970) Nature (London) 337, 650-655.
21. Towbin, H., Staehelin, T. & Gordon, J. (1979) Proc. Natl. Acad. Sci. USA 76, 4350-4354.
22. Blose, D. H., Meltzer, D. I. & Feramisco, J. R. (1984) J. Cell Biol. 98, 847-858.
23. Gaglio, T., Saredi, A. & Compton, D. A. (1995) J. Cell Biol. 131, 693-708.
24. Gilad, S., Khosravi, R., Shkedy, D., Uziel, T., Ziv, Y., et al. (1996) Hum. Mol. Genet. 5, 433-439.
25. Byrd, P. J., McConville, C. M., Cooper, P., Parkhill, J., Stankovic, T., McGuire, G. M., Thick, J. A. & Taylor, A. M. R. (1996) Hum. Mol. Genet. 5, 145-149.
26. Meyn, M. S. (1995) Cancer Res. 55, 5991-6001.
27. Shiloh, Y., Tabor, E. & Becker, Y. (1982) Carcinogenesis 3, 815-820.
28. Silver, P. A. (1991) Cell 64, 489-497.
29. Baumann, B., Potash, M. J. & Kohler, G. (1985) EMBO J. 4, 351-359.
30. Lehrman, M. A., Schneider, W. J., Brown, M. S., Davis, C. G., Elhammer, A., Russell, D. W. & Goldstein, J. L. (1987) J. Biol. Chem. 262, 401-410.
31. Brody, L. C., Mitchell, G. A., Obie, C, Michaud, J., Steel, G., Fontaine, G., Robert, M.-F., Sipila, I, Kaiser-Kupfer, M. & Valle, D. (1992) J. Biol. Chem. 267, 3302-3307.
32. Pakula, A. A. & Sauer, R. T. (1989) Annu. Rev. Genet. 23, 289-310.
33. Kojis, T. L., Schreck, R. R., Gatti, R. A. & Sparkes, R. S. (1989) Hum. Genet. 83, 347-352.
34. Ganesh, A., North, P. & Thacker, J. (1993) Mutat. Res. 299, 251-259.
35. Cornforth, M. N. & Bedford, J. S. (1985) Radiat. Res. 111, 385-405.
36. Pandita, T. K. & Hittleman, W. N. (1992) Radiat. Res. 131, 214-223.
37. Zampetti-Bosseler, F. & Scott, D. (1981) Int. J. Radiat. Biol. 39, 547-558.
38. Weinert, T. A. & Hartwell, L. H. (1990) Mol. Cell. Biol. 10, 6554-6564.
39. Taylor, A. M. R., Metcalfe, J. A., Thick, J. & Mak, Y.-F. (1996) Blood 87, 423-438.
40. Barlow, C., Hirotsune, S., Paylor, R., Liyanage, M., Eckhaus, M., Collins, F., Shiloh, Y., Crawley, J., Reid, T., Tagle, D. & Wynshaw-Boris, A. (1996) Cell 86, 159-171.
41. Xu, Y., Ashley, T., Brainerd, E. E., Bronson, R. T., Meyn, M. S. & Baltimore, D. (1996) Genes Dev. 10, 2411-2422.
42. Anderson, C. W., Lees-Miller, S. P. (1992) Crit. Rev. Eukaryotic Gene Expression 2, 283-314.
43. Blunt, T., Finnie, N. J., Taccioli, G. E., Smith, GCM, Demengeot, J., Gottleib, T. M., Mizuta, R., Varghese, A. J., Alt, F. W., Jeggo, P. A. & Jackson, S. P. (1995) Cell 80, 813-823.
44. Keegan, K. S., Holtzman, D. A., Plu, A. W., Christenson, E. R., Brainerd, E. E., Flaggs, G., Bentley, N. J., Taylor, E. M., Meyn, M. S., Moss, S. B., Carr, A. M., Ashley, T. & Hoekstra, M. F. (1996) Genes Dev. 10, 2423-2437.
45. Hartley, K. O., Gell, D., Smith, G. C. M., Zhang, H., Divecha, N., Connelly, M. A., Admon, A., Lees-Miller, S. P., Anderson, C. W. & Jackson, S. P. (1995) Cell 82, 849-856.
46. Sanchez, Y., Desany, B. A., Jones, W. J., Liu, Q., Wang, B. & Elledge, S. J. (1996) Science 271, 357-360.