Chapter 10. Phosphodiesterases 4 Inhibitors

Annual Reports in Medicinal Chemistry

Volumn 33, Issue C, 1998, Pages 91-109

  Burnouf, Catherine ^a   Pruniaux, Marie Pierre ^a   Szilagyi, Corinne M ^a  

^a Institut de Recherche Jouveinal   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0002535991     PISSN: 00657743     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-7743(08)61075-1     Document Type: Chapter

References (125)

1. Giembicz M.A. Biochem. Pharmacol. 43 (1992) 2041
2. Drugs and the lung; T.J. Torphy, K.J. Murray and J.R.S. Arch, Eds., C.P. Page and W.J. Metzger, Raven Press, New York, (1994)
3. Torphy T.J., and Undem B.J. Thorax 46 (1991) 512
4. Palfreyman M.N., and Souness J.E. In: Ellis G.P., and Luscombe D.K. (Eds). "Progress in Medicinal Chemistry" 33 (1996), Elsevier Science, B.V. 1
5. Molnar-Kimber K., Yonno L., Heaslip R.J., and Weichman B.M. Agents Actions 39 (1993) C77
6. Hartman D.A., Ochalski S.J., and Carlson R.P. Agents Actions 39 (1993) C70
7. Dent G., Giembycz M.A., Rabe K.F., and Barnes P.J. Br. J. Pharmacol. 103 (1991) 1339
8. Giembycz M.A., Dent G., Virdee H., Rabe K.F., Evans P.M., and Barnes P.J. Br. J. Pharmacol. 112 (1994) 26P
9. Nielson C.P., Vestal R.E., Sturm R.J., and Heaslip R.J. J. Allergy Clin. Immunol. 86 (1990) 801
10. Peachell P.T., Undem B.J., Schleimer R.P., MacGlashan Jr. D.W., Lichtenstein L.M., Cieslinski L.B., and Torphy T.J. J. Immunol. 148 (1992) 2503
11. Schade F.U., and Schudt C. Eur. J. Pharmacol. 230 (1993) 9
12. Fonteh A.N., Winkler J.D., Torphy T.J., Heravi J., Undem B.J., and Chilton F.H. J. Immunol. 151 (1993) 339
13. Raeburn D., Woodman V., Buckley G., and Karlsson J.A. Eur. Respir. J. 4 suppl. 14 (1991) 590S
14. Turner C.R., Andresen C.J., Smith W.B., and Watson J.W. Am. J. Respir. Crit. Care Med. 149 (1994) 1153
15. Prabhakar U., Lipscutz D., O'Leary Bartus J., Slivjak M.J., Smith E.F., Lee J.C., and Esser K.M. Int. J. Immunopharmac. 16 (1994) 805
16. Pharmaproject, (April 1998)
17. rd International Conference on Cyclic Nucleotides Phosphodiesterases: From Genes to Therapies, Glasgow, (July 1996)
18. Bou, J., Llupià, J., Cardelus, I., Puig, J., Salcedo, C., Gras, J., Beleta, J., Fernandez, A.G., Llenas, J., Berga, P., Gristwood, R.W. and Palacios, J.M., 3rd International Conference on Cyclic Nucleotides Phosphodiesterases: From Genes to Therapies, Glasgow, (July 1996)
19. Heaslip R.J., and Evans D.Y. Eur. J. Pharmacol. 286 (1995) 281
20. Santamaria L.F., and Palacios J.M. J. Beleta. BR. J. Pharmacol. 121 (1997) 1150
21. Shishijo M., Shimizu Y., Hiramatsu K., Inagaki N., Tagaki K., and Nagai H. Int. Arch. Allergy Immunol. 114 (1997) 348
22. Underwood D.C., Matthews J.K., Osborn R.R., Bochnowicz S., and Torphy T.J. J. Pharmacol. Exp. Ther. 280 (1997) 210
23. Essayan, D.M., Huang, S.K., Kagey-Sobotka, A. & Lichtenstein, L.M., 99, 28, (1997)
24. Foissier L., Lonchampt M., Coge F., and Canet E. J. Pharmacol., Exp. Ther. 278 (1996) 1484
25. Barnette M.S., Christensen S.B., Essayan D.M., Grous M., Prabhakar U., Rush J.A., Kagey-Sobota A., and Torphy T.J. J. Pharmacol. Exp. Ther. 284 (1998) 420
26. Christensen S.B., Guider A., Forster C.J., Gleason J.G., Bender P.E., Karpinski J.M., DeWolf Jr. W.E., Barnette M.S., Underwood D.C., Griswold D.E., Cielinski L.B., Burman M., Bochnowicz S., Osborn R.R., Manning C.D., Grous M., Hillegas L.M., O'Leary Bartus J., Ryan M.D., Eggleston D.S., Haltiwanger R.C., and Torphy T.J. J. Med. Chem. 41 (1998) 821
27. Torphy T.J., Christensen S.B., Barnette M.S., Burman M., Cieslinski L.B., and DeWolf Jr. W.E. Eur. Resp. J. 10 (1997) 313S
28. Heaslip R.J., Lombardo L.J., Golankiewicz J.M., Ilsemann B.A., Evans D.Y., Sickels B.D., Mudrick J.K., Babli J., and Weichman B.M. J. Pharmacol. Exp. Ther. 268 (1994) 888
29. Howell R.E., Woeppel S.L., Howell D.E., Rubin E.B., Jenkins L.P., Golankiewicz J.M., Lombardo L.J., and Heaslip R.J. Inflamm. Res. 44 suppl 2 (1995) S-172
30. Norman P. Drugs News and Perspectives 10 (1997) 501
31. Drugs Future, 21, 858, (1996)
32. Naline E., Quian Y., Advenier C., Raeburn D., and Karlsson J.A. Br. J. Pharmacol. 118 (1996) 1939
33. Jonker G.J., Tijhuis G.J., and De Monchy J.G.R. Eur. Respir. J. Suppl. 9 (1996) 23
34. th American Chemical Society National Meeting, Orlando, 212, (1-2), MEDI 115, (1996)
35. Cohan V.L., Showell H.J., Fisher D.A., Pazoles C.J., Watson J.W., Turner C.R., and Cheng J.B. J. Pharmacol. Exp. Ther. 278 (1996) 1356
36. Cheng J.B., Watson J.W., Pazoles C.J., Eskra J.D., Griffiths R.J., Cohan V.L., Turner C.R., Showell H.J., and Pettipher E.R. J. Pharmacol. Exp. Ther. 280 (1997) 621
37. Wright K.F., Turner C.R., Jayasinghe-Beck R., Cohen V.L., Cheng J.B., and Watson J.W. Can. J. Physiol. Pharmacol. 75 (1997) 1001
38. Turner C.R., Cohan V.L., Cheng J.B., Showell H.J., Pazoles C.J., and Watson J.W. J. Pharmacol. Exp. Ther. 278 (1996) 1349
39. Chambers R.J., Marfat A., Cheng J.B., Cohan V.L., Damon D.B., Duplantier A.J., Hibbs T.A., Jenkinson T.H., Johnson K.L., Kraus K.G., Pettipher E.R., Salter E.D., Shirley J.T., and Umland J.P. Bioorg. Med. Chem. Lett. 7 (1997) 739
40. Prous Science Trilogy and Cipsline Databases
41. O'Brien C. Mol. Medicine Today (1997) 369
42. Marx D., Egerland U., Hartung T., Sauer A., Szelenyi I., and Wendel A. J. Allergy Clin. Immunol. S444 (1997) 1803
43. Calvet, A., Dahl, S.G., Junien, J-L., Moodley, I. and Pascal, Y., WO 9611690-A1
44. Calvet, A., Dahl, S.G., Jacobelli, H., Pascal, Y. and Payne, A., WO 9736905
45. th American Chemical Society National Meeting, Dallas, Texas, 215, MEDI 50, (1998)
46. th American Chemical Society National Meeting, Dallas, Texas, 215, MEDI 8, (1998)
47. Cavalla D., Gale D.D., Spina D., Seeds F., Banner K., Page C.P., Wong R.H., Jordan S., Burch R.M., and Chasin M. Amer. J. Resp. Crit. Care Med. 155 (1997) A660 (4, Part 2)
48. th American Chemical Society National Meeting, Dallas, 215, MEDI 49, (1998)
49. th American Chemical Society National Meeting, Las Vegas, 214, MEDI 245, (1997)
50. Guay, D., Girard, Y. and Ducharme, Y., WO 9722585
51. Pharm. n° 5477, Pharmaproject (April 1998)
52. Pharm. n° 5445, Pharmaproject (April 1998)
53. Lüönd, R. & Pombo-Villar, E. WO 9718208
54. Kaminuma O., Yoshikawa H., Yamashina S., Wada K., and Ikesawa I. Jpn. J. Allargol. 44 (1995) Abst 300
55. Kaminuma O., Kikkawa H., Matsubara S., and Ikezawa K. Jpn. J. Pharmacol. 72 (1996) 1
56. Drugs of the Future, 22, 729, (1997)
57. Kaminuma O., Mori A., Suko M., Kikkawa H., Matsubara S., and Ikezawa K. J. Pharmacol. Exp. Ther. 279 (1996) 240
58. Kaminuma O., Mori A., Suko M., Nishisaki Y., Kikkawa H., Ikezawa K., and Okudaira H. Int. Arch. Allergy Immunol. 111 (1996) 16
59. Kaminuma O., Kikkawa H., Matsubara S., and Ikezawa K. Int. Arch. Allergy Immunol. 112 (1997) 406
60. Matsubara S., Fushimi K., Kaminuma O., Kikkawa H., Iwasaki H., Naito H., and Ikesawa K. Jpn. J. Pharmacol. 71 suppl.1 (1996) Abst 301
61. Fujii K., Kohrogi H., Iwagoe H., Hamamoto J., Hirata N., Goto E., Kawano O., Wada K., Yamagata S., and Ando M. J. Pharmacol. Exp. Ther. 279 (1996) 240
62. Ukita, T., Kobe-shi, H., Ikesawa, K. and Yamagata, S., EP 748805-A1
63. Pharmaproject April 1998, Pharm. n° 5317
64. th American Chemical Society National Meeting, Las Vegas, 213, MEDI 91, (1997)
65. Manabe H., Akuta K., Sejimo H., Kawasaki H., Nukui E., Ichimura M., Kase H., Kawakita T., Suzuki F., Kitamura S., Sato S., and Ohmori K. Eur. J. Pharmacol. 332 (1997) 97
66. Fujimura M., Kuta T., Myou S., Tachibana H., and Matsuda T. Eur. J. Pharmacol. 327 (1997) 57
67. Manabe H., Akuta K., Okamura K., and Ohmori K. Int. Arch. Allergy Immunol. 114 (1997) 389
68. Loe, B.E. and Wilhelm, R.S., WO 9602541
69. Bourguignon J.J., Désaubry L., Raboisson P., Wermuth C.-G., and Lugnier C. J. Med. Chem. 40 (1997) 1768
70. Sawanishi H., Suzuki H., Yamamoto S., Waki Y., Kasugai S., Ohyya K., Suzuki N., Miyamoto K.-I., and Takagi K. J. Med. Chem. 40 (1997) 3248
71. Polymeropoulos E.E., and Höfgen N. Quant. Struct.-Act. Relat. 16 (1997) 231
72. Jacobitz S., Ryan M.D., McLaughlin M.M., Livi G.P., DeWolf Jr. W.E., and Torphy T.J. Mol. Pharmacol. 51 (1997) 999
73. Kleinman E.F., Campbell E., Giordano L.A., Cohan V.L., Jenkinson T.H., Cheng J.B., Shirley J.T., Pettipher E.R., Salter E.D., Hibbs T.A., DiCapua F.M., and Bordner J. J. Med. Chem. 41 (1998) 266
74. Percival M.D., Yeh B., and Falgueyret J.-P. Biochem. Biophys. Res. Commun. 241 (1997) 175
75. Schneider H.H., Schmiechen R., Brezinski M., and Seidler J. Eur. J. Pharmacol. 127 (1986) 105
76. Torphy T.J., Stadel J.M., Burman M., Cieslinski L.B., McLaughlin M.M., White J.R., and Livi G.P. J. Biol. Chem. 267 (1992) 1798
77. Torphy T.J., DeWolf Jr. W.E., Green D.W., and Livi G.P. Agents Actions Suppl. 43 (1993) 51
78. Rocque W.J., Holmes W.D., Patel I.R., Dougherty R.W., Ittoop O., Overton L., Hoffman C.R., Wisely G.B., Willard D.H., and Luther M.A. Protein Express. Purification 9 (1997) 191
79. Heaslip R.J., and Evans D.Y. Eur. J. Pharmacol. 286 (1995) 281
80. Barnette, M.S., Challenges for Drug Discovery. New Drugs for Asthma-III, Montebello, Québec, July, 1994
81. Dal Piaz V., Giovannoni M.P., Castellana C., Palacios J.M., Beleta J., Doménech T., and Segarra V. J. Med. Chem 40 (1997) 1417
82. Hugues B., Owens R., Perry M., Warrellow G., and Allen R. Drug Discov. Today 2 (1997) 89
83. Souness J.E., and Rao S. Cell. Signal. 9 (1997) 227
84. Barnette M.S., Christensen S.B., Underwood D.C., and Torphy T.J. Pharmacol. Rev. Commun. 8 (1997) 65
85. Muller T., Engels P., and Fozard J.R. Trends Pharmacol. Sci. 17 (1996) 294
86. Torphy T.J. Am. J. Resp. Crit. Care Med. 157 (1998) 351
87. Souness J.E., Griffin M., Maslen C., Ebsworth K., Scott L.C., Pollock K., Palfreyman M.N., and Karlsson J.-A. Br. J. Pharmacol. 118 (1996) 649
88. Jacobitz S., McLaughin M.M., Livi G.P., Burman M., and Torphy T.J. Mol. Pharmacol. 50 (1996) 891
89. Rocque W.J., Tian G., Wiseman J.S., Holmes W.D., Zajac-Thompson I., Willard D.H., Wisely G.B., Clay W.C., Kadwell S.H., Hoffman C.R., and Luther M.A. Biochemistry 36 (1997) 14250
90. Milatovich A., Bolger G., Michaeli T., and Francke U. Somatic Cell Mol. Genet. 20 (1994) 75
91. Horton Y.M., Sullivan M., and Houslay M.D. Biochem. J. 308 (1995) 683
92. Szpirer C., Szpirer J., Riviere M., Swinnen J., Vicini E., and Conti M. Cytogenet. Cell. Genet. 69 (1995) 11
93. Bolger G., Michaeli T., Martins T., Souness T.S.E., and Rao S. Cell. Signal. 9 (1997) 227
94. Engels P., Fichtel K., and Lubbert H. FEBS Lett. 350 (1994) 291
95. Conti M., Swinnen J.V., Tsikalas K.E., and Jin S.L.C. Adv. Second Messenger Protein Phosphoryl. Res. 25 (1992) 87
96. Bolger G.B. Cell. Signal. 6 (1994) 851
97. Beavo J.A., Conti M., and Heaslip R.J. Mol. Pharmacol. 46 (1994) 399
98. Davies R.L., Takaysasu H., Eberwine M., and Myres J. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 3604
99. Swinnen J.V., Tsikalas K.E., and Conti M. J. Biol. Chem. 266 (1991) 18370
100. Wang P., Myers J.G., Wu P., Cheewatrakoolpong B., Egan R.W., and Billah M. Biochem., Biophys. Res. Commun. 234 (1997) 320
101. Engels P., Sullivan M., Müller T., and Lübbert H. FEBS Lett. 358 (1995) 305
102. Sekut L., Yarnall D., Stimpson S.A., Noel L.S., Bateman-Fite R., Clark R.L., Brackeen M.F., Menius Jr. J.A., and Connolly K.M. Clin. Exp. Immunol. 100 (1995) 126
103. Eigler A., Siegmund B., Emmerich U., Baumann K.H., Hartmann G., and Endres S. J. Leukocyte Biol. 63 (1998) 101
104. Boguniewicz M. Current opinion in Pediatrics. 9 (1997) 577
105. Banner K.H., Roberts N.M., and Page C.P. BR. J. Pharmacol. 116 (1995) 3169
106. Eigler, Sinha B., Hartmann G., and Endres S. Immunol., Today 18 (1997) 487
107. Feldmann M., Brennan S.M., and Maini R. Ann. Rev. Immunol. 14 (1996) 397
108. Myers L.K., Rosloniec E.F., Cremer M.A., and Kang A.H. Kife Sc. 61 (1997) 1861
109. Nyman U.N., Müssener A., Larsson E., Lorentzen J., and Klareskog L. Clin. Exp. Immunol. 108 (1997) 415
110. Dinter H., Onuffer J., Faulds D., and Perez H.D. J. Mol. Med. 75 (1997) 95
111. Genain C.P., Roberts T., Davis R.L., Nguyen M., Ucchelli A., Faulds D., Li Y., Hedgpeth J., and Hauser S.L. Proc. Natl. Acad. Sci., USA 92 (1995) 3601
112. Sommer N., Löschmann P.A., Northoff G.H., Weller M., Steinbrecher A., Steinbach J.P., Lichtenfels R., Meyermann R., Riethmüller A., Fontana A., Dichgans J., and Martin R. Nat. Med. 1 (1995) 244
113. Jung S., Zielasek J., Kollner G., Donhauser T., Toyka K., and Hartung H.P. J. Neuroimmunol. 68 (1996) 1
114. Sommer N., Martin R., McFarland H.F., Quigley L., Cannella B., Raine C.S., Scott D.E., Löschmann P.A., and Racke M.K. J. Neuroimmunol. 79 (1997) 54
115. Constantinescu C.S., Hilliard B., Lavi E., Ventura E., Venkatesh V., and Rostami A. J. Neurol. Sci. 143 (1996) 14
116. Carcillo J.A., Herzer W.A., Mi Z., Thomas N.J., and Jackson E.K. J. Pharmacol. Exp. Ther. 279 (1996) 1197
117. Staudinger T., Presterl E., Graninger W., Locker G.J., Knapp S., Laczika K., Klappacher G., Stoiser B., Wagner A., Tesinsky P., Kordova H., and Frass M. Intensive Care Med. 22 (1996) 888
118. Cardelus I., Gras J., Jauregui J., Llenas J., and Palacios J.M. Eur. J. Pharmacol. 299 (1996) 153
119. Van Deventer S.J.H. Gut 40 (1997) 443
120. Reimund J.M., Dumont D., Muller C.D., Kenney J.S., Kedinger M., Baumann R., Poindron P., and Duclos B. Gut 40 (1997) 475
121. Bauditz J., Haemling J., Ortner M., Lochs H., Raedler A., and Schreiber S. Gut 40 (1997) 470
122. Peterson T.C., and Davey K. Effect of acute pentoxifylline treatment in an experimental model of colitis. Alimentary Pharmacol. Ther. 11 (1997) 575
123. Gantner F., Küsters S., Wendel A., Hatzelmann A., Schudt C., and Tiegs G. J. Pharmacol. Exp. Ther. 280 (1997) 53
124. Wagner R.S., Smith C.J., Taylor A.M., and Rhoades R.A. J. Pharmacol. Exp. Ther. 282 (1997) 1650
125. Miyamoto K., Waki Y., Horita T., Kasugai S., and Ohya K. Biochem. Pharmacol. 54 (1997) 613