Effect of T-440, a novel type IV phosphodiesterase inhibitor, on allergen-induced immediate and late asthmatic reaction and leukocyte infiltration into the airways of guinea pigs

International Archives of Allergy and Immunology

Volumn 112, Issue 4, 1997, Pages 406-411

  Kaminuma, Osamu ^a   Kikkawa, Hideo ^a   Matsubara, Shigeki ^a   Ikezawa, Katsuo ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Airway inflammation; Asthma; Eosinophils; Guinea pig; Neutrophils; Phosphodiesterase inhibitor

Indexed keywords

4 [6,7 DIETHOXY 2,3 BIS(HYDROXYMETHYL) 1 NAPHTHYL] 1 (2 METHOXYETHYL) 2(1H) PYRIDINONE; METYRAPONE; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; UNCLASSIFIED DRUG;

AIRWAY; ANIMAL EXPERIMENT; ARTICLE; ASTHMA; EOSINOPHIL; GUINEA PIG; LEUKOCYTE; LUNG LAVAGE; MALE; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0030906509     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000237488     Document Type: Article

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