-
1
-
-
0027181055
-
Multiple sclerosis. Pathology of recurrent lessions
-
Prineas JW, Barnard RO, Rovesz, T. Kwon EE, Sharer L, Cho E-S (1993) Multiple sclerosis. Pathology of recurrent lessions. Brain 116:681-693
-
(1993)
Brain
, vol.116
, pp. 681-693
-
-
Prineas, J.W.1
Barnard, R.O.2
Rovesz, T.3
Kwon, E.E.4
Sharer, L.5
Cho, E.-S.6
-
2
-
-
0028578038
-
Patterns of oligodendroglia pathology in multiple sclerosis
-
Ozawa K, Suchanek G, Breitschopf H, Bruck W, Budka H, Jelliger K, Lassmann H (1994) Patterns of oligodendroglia pathology in multiple sclerosis. Brain 117:1311-1322
-
(1994)
Brain
, vol.117
, pp. 1311-1322
-
-
Ozawa, K.1
Suchanek, G.2
Breitschopf, H.3
Bruck, W.4
Budka, H.5
Jelliger, K.6
Lassmann, H.7
-
3
-
-
0020676803
-
Multiple sclerosis: Distribution of T-cell subsets within active chronic lesions
-
Traugott U, Reinherz EL, Raine CS (1983) Multiple sclerosis: distribution of T-cell subsets within active chronic lesions. Science 219:308-310
-
(1983)
Science
, vol.219
, pp. 308-310
-
-
Traugott, U.1
Reinherz, E.L.2
Raine, C.S.3
-
4
-
-
0022651246
-
Immunoregulatory molecules and IL-2 receptors identified in multiple sclerosis brain
-
Hofman FM, von Hanwehr RI, Dinarello CA, Mizel SB, Hinton, D, Merril, JE (1986) Immunoregulatory molecules and IL-2 receptors identified in multiple sclerosis brain. J Immunol 136:3239-3245
-
(1986)
J Immunol
, vol.136
, pp. 3239-3245
-
-
Hofman, F.M.1
Von Hanwehr, R.I.2
Dinarello, C.A.3
Mizel, S.B.4
Hinton, D.5
Merril, J.E.6
-
5
-
-
45249128922
-
MS: A localized immune disease of the central nervous system
-
Calder V, Owen S, Watson C, Feldman M, Davidson A (1989) MS: a localized immune disease of the central nervous system. Immunol Today 10:99-103
-
(1989)
Immunol Today
, vol.10
, pp. 99-103
-
-
Calder, V.1
Owen, S.2
Watson, C.3
Feldman, M.4
Davidson, A.5
-
6
-
-
0025852567
-
Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
-
Selmaj K, Raine CS, Canella B, Brosnan CF (1991) Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest 87:949-954
-
(1991)
J Clin Invest
, vol.87
, pp. 949-954
-
-
Selmaj, K.1
Raine, C.S.2
Canella, B.3
Brosnan, C.F.4
-
8
-
-
0027845224
-
Cytokine mRNA expression in inflammatory multiple sclerosis lesions: Detection by non-radioactive in situ hybridization
-
Woodroofe MN, Cuzner ML (1993) Cytokine mRNA expression in inflammatory multiple sclerosis lesions: detection by non-radioactive in situ hybridization. Cytokine 5:583-588
-
(1993)
Cytokine
, vol.5
, pp. 583-588
-
-
Woodroofe, M.N.1
Cuzner, M.L.2
-
9
-
-
0023858304
-
Interferon-gamma and Ia antigen are present on astrocytes in active chronic multiple sclerosis lesions
-
Traugott U, Lebon P (1988) Interferon-gamma and Ia antigen are present on astrocytes in active chronic multiple sclerosis lesions. J Neurol Sci 84:257-262
-
(1988)
J Neurol Sci
, vol.84
, pp. 257-262
-
-
Traugott, U.1
Lebon, P.2
-
10
-
-
0026485415
-
Tumor necrosis factor α induces adhesion molecule expression on human fetal astrocytes
-
Hurwitz AA, Lyman WD, Guida MP, Calderon TM, Berman JW (1992) Tumor necrosis factor α induces adhesion molecule expression on human fetal astrocytes. J Exp Med 176:1631-1636
-
(1992)
J Exp Med
, vol.176
, pp. 1631-1636
-
-
Hurwitz, A.A.1
Lyman, W.D.2
Guida, M.P.3
Calderon, T.M.4
Berman, J.W.5
-
11
-
-
0026596353
-
In vivo relationship of tumor necrosis factor-α to blood-brain barrier damage in patients with active multiple sclerosis
-
Sharief MK, Thompson EJ (1992) In vivo relationship of tumor necrosis factor-α to blood-brain barrier damage in patients with active multiple sclerosis. J Neuroimmunol 38:27-34
-
(1992)
J Neuroimmunol
, vol.38
, pp. 27-34
-
-
Sharief, M.K.1
Thompson, E.J.2
-
12
-
-
0023904746
-
Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
-
Selmaj K, Raine CS (1988) Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol 23:339-346
-
(1988)
Ann Neurol
, vol.23
, pp. 339-346
-
-
Selmaj, K.1
Raine, C.S.2
-
13
-
-
0025000863
-
An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis
-
Ruddle NH, Bergman CM, McGrath KM, Lingenheld EG, Grunnet ML, Padula SJ, Clark RB (1990) An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis. J Exp Med 172:1193-1200
-
(1990)
J Exp Med
, vol.172
, pp. 1193-1200
-
-
Ruddle, N.H.1
Bergman, C.M.2
McGrath, K.M.3
Lingenheld, E.G.4
Grunnet, M.L.5
Padula, S.J.6
Clark, R.B.7
-
14
-
-
0026094706
-
Anti-tumor necrosis factor therapy abrogates autoimmune demyelination
-
Selmaj K, Raine CS, Cross AH (1991) Anti-tumor necrosis factor therapy abrogates autoimmune demyelination. Ann Neurol 30:694-700
-
(1991)
Ann Neurol
, vol.30
, pp. 694-700
-
-
Selmaj, K.1
Raine, C.S.2
Cross, A.H.3
-
15
-
-
0028855346
-
Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I
-
Selmaj K, Papierz W, Glabinski A, Kohno T (1995) Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I. J Neuroimmunol 56:135-141
-
(1995)
J Neuroimmunol
, vol.56
, pp. 135-141
-
-
Selmaj, K.1
Papierz, W.2
Glabinski, A.3
Kohno, T.4
-
16
-
-
0027315234
-
The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-α production by human mononuclear cells
-
Semmler J, Wachtel H, Endres S (1993) The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-α production by human mononuclear cells. Int J Immunopharmac 15:409-413
-
(1993)
Int J Immunopharmac
, vol.15
, pp. 409-413
-
-
Semmler, J.1
Wachtel, H.2
Endres, S.3
-
17
-
-
0028955945
-
The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis
-
Sommer N, Löschmann P-A, Northoff GH, Weller M, Steinbrecher A, Steinbach JP, Lichtenfels R, Meyermann R, Riethmüller A, Fontana A, Dichgans J, Martin R (1995) The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis. Nature Med 1:244-248
-
(1995)
Nature Med
, vol.1
, pp. 244-248
-
-
Sommer, N.1
Löschmann, P.-A.2
Northoff, G.H.3
Weller, M.4
Steinbrecher, A.5
Steinbach, J.P.6
Lichtenfels, R.7
Meyermann, R.8
Riethmüller, A.9
Fontana, A.10
Dichgans, J.11
Martin, R.12
-
18
-
-
0028912608
-
Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor
-
Genain CP, Roberts T, Davis RL, Nguyen M-H, Uccelli A, Faulds D, Li Y, Hedgepeth J, Hauser SL (1995) Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor. Proc Natl Acad Sci USA 92:3601-3605
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3601-3605
-
-
Genain, C.P.1
Roberts, T.2
Davis, R.L.3
Nguyen, M.-H.4
Uccelli, A.5
Faulds, D.6
Li, Y.7
Hedgepeth, J.8
Hauser, S.L.9
-
19
-
-
0030047730
-
Gating by cyclic AMP: Expanded role for an old signaling pathway
-
Iyengar R (1996) Gating by cyclic AMP: expanded role for an old signaling pathway. Science 271:461-463
-
(1996)
Science
, vol.271
, pp. 461-463
-
-
Iyengar, R.1
-
20
-
-
0028136159
-
Multiple cyclic nucleotide phosphodiesterases
-
Beavo JA, Conti M, Heaslip RJ (1994) Multiple cyclic nucleotide phosphodiesterases. Mol Pharmacol 46:399-405
-
(1994)
Mol Pharmacol
, vol.46
, pp. 399-405
-
-
Beavo, J.A.1
Conti, M.2
Heaslip, R.J.3
-
21
-
-
0025999955
-
Cyclic nucleotide phosphodiesterases: Pharmacology, biochemistry and function
-
Thompson WT (1991) Cyclic nucleotide phosphodiesterases: pharmacology, biochemistry and function. Pharmacol Therapeut 51:13-33
-
(1991)
Pharmacol Therapeut
, vol.51
, pp. 13-33
-
-
Thompson, W.T.1
-
22
-
-
0029009878
-
Recent progress in understanding the hormonal regulation of phosphodiesterases
-
Conti M, Nemoz G, Sette C, Vicini E (1995) Recent progress in understanding the hormonal regulation of phosphodiesterases. Endocrine Rev 16:370-389
-
(1995)
Endocrine Rev
, vol.16
, pp. 370-389
-
-
Conti, M.1
Nemoz, G.2
Sette, C.3
Vicini, E.4
-
24
-
-
0026734249
-
Could isozyme-selective phosphodiesterase inhibitors render bronchodilator therapy redundant in the treatment of bronchial asthma?
-
Giembyzc MA (1992) Could isozyme-selective phosphodiesterase inhibitors render bronchodilator therapy redundant in the treatment of bronchial asthma? Biochem Pharamacol 43: 2041-2051
-
(1992)
Biochem Pharamacol
, vol.43
, pp. 2041-2051
-
-
Giembyzc, M.A.1
-
25
-
-
0001825786
-
m cyclic AMP phosphodiesterases: A family of related enzymes
-
Beavo J, Houslay MD (eds) Wiley, Chichester
-
m cyclic AMP phosphodiesterases: a family of related enzymes. In: Beavo J, Houslay MD (eds) Cyclic nucleotide phosphodiesterases: structure, regulation and drug action, vol 2. Wiley, Chichester, pp 243-266
-
(1990)
Cyclic Nucleotide Phosphodiesterases: Structure, Regulation and Drug Action
, vol.2
, pp. 243-266
-
-
Conti, M.1
Swinnen, J.V.M.2
-
26
-
-
0028360098
-
The ratPDE3/IVd phosphodiesterase gene codes for multiple proteins differentially activated by cAMP-dependent protein kinase
-
Sette C, Vicini E, Conti M (1994) The ratPDE3/IVd phosphodiesterase gene codes for multiple proteins differentially activated by cAMP-dependent protein kinase. J Biol Chem 269: 18271-18274
-
(1994)
J Biol Chem
, vol.269
, pp. 18271-18274
-
-
Sette, C.1
Vicini, E.2
Conti, M.3
-
27
-
-
0028839684
-
Activation and selective inhibition of a cyclic AMP-specific phoshodiesterase, PDE-4D3
-
Alvarez R, Sette C, Yang D, Eglen RM, Wilhelm R, Shelton ER, Conti M (1995) Activation and selective inhibition of a cyclic AMP-specific phoshodiesterase, PDE-4D3. Mol Pharmac 48:616-622
-
(1995)
Mol Pharmac
, vol.48
, pp. 616-622
-
-
Alvarez, R.1
Sette, C.2
Yang, D.3
Eglen, R.M.4
Wilhelm, R.5
Shelton, E.R.6
Conti, M.7
-
28
-
-
34447497335
-
Identification and functional characterization of various phosphorylated forms of human recombinant rolipram sensitive cAMP specific type IV phosphodiesterase
-
abstract
-
Luther M, Holmes B, Kassel D, Lenhard J, Hamacher L, Burkhart W, Moyer M, Patel I, Overton L, Hoffmann C, Rocque W (1994) Identification and functional characterization of various phosphorylated forms of human recombinant rolipram sensitive cAMP specific type IV phosphodiesterase. FASEB J 2141:A370 (abstract)
-
(1994)
FASEB J
, vol.2141
-
-
Luther, M.1
Holmes, B.2
Kassel, D.3
Lenhard, J.4
Hamacher, L.5
Burkhart, W.6
Moyer, M.7
Patel, I.8
Overton, L.9
Hoffmann, C.10
Rocque, W.11
-
29
-
-
0022516667
-
Rolipram, a novel antidepressant drug, reverses the hypothermia and hypokinesia of monoamine-depleted mice by an action beyond postsynaptic monoamine receptors
-
Wachtel H, Schneider HH (1986) Rolipram, a novel antidepressant drug, reverses the hypothermia and hypokinesia of monoamine-depleted mice by an action beyond postsynaptic monoamine receptors. Neuropharmacol 25:1119-1126
-
(1986)
Neuropharmacol
, vol.25
, pp. 1119-1126
-
-
Wachtel, H.1
Schneider, H.H.2
-
30
-
-
0022459284
-
Stereospecific binding of the antidepressant rolipram to brain protein structures
-
Schneider HH, Schmiechen R, Brezinski M, Seidler J (1986) Stereospecific binding of the antidepressant rolipram to brain protein structures. Eur J Pharmacol 127:105-115
-
(1986)
Eur J Pharmacol
, vol.127
, pp. 105-115
-
-
Schneider, H.H.1
Schmiechen, R.2
Brezinski, M.3
Seidler, J.4
-
31
-
-
0028847783
-
Discriminative stimulus properties of the stereoisomers of the phosphodiesterase inhibitor rolipram
-
Scheider HH, Yamaguchi M, Andrews JS Stephens DN (1995) Discriminative stimulus properties of the stereoisomers of the phosphodiesterase inhibitor rolipram. Pharmacol Biochem Behav 50:211-217
-
(1995)
Pharmacol Biochem Behav
, vol.50
, pp. 211-217
-
-
Scheider, H.H.1
Yamaguchi, M.2
Andrews, J.S.3
Stephens, D.N.4
-
32
-
-
0015231739
-
Multiple cyclic nucleotide phosphodiesterase activities from rat brain
-
Thompson WJ, Appleman MM (1971) Multiple cyclic nucleotide phosphodiesterase activities from rat brain. Biochem 10:311-316
-
(1971)
Biochem
, vol.10
, pp. 311-316
-
-
Thompson, W.J.1
Appleman, M.M.2
-
34
-
-
0026528829
-
Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast
-
Torphy TJ, Stadel JM, Burman M, Cieslinski LB, McLaughlin MM, White JR, Livi GP (1992) Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast. J Biol Chem 267:1798-1804
-
(1992)
J Biol Chem
, vol.267
, pp. 1798-1804
-
-
Torphy, T.J.1
Stadel, J.M.2
Burman, M.3
Cieslinski, L.B.4
McLaughlin, M.M.5
White, J.R.6
Livi, G.P.7
-
35
-
-
0027138677
-
Use of a yeast expression system for the isolation and analysis of drug-resistant mutants of a mammalian phosphodiesterase
-
Pillai R, Kytle K, Reyes A, Colicelli J (1993) Use of a yeast expression system for the isolation and analysis of drug-resistant mutants of a mammalian phosphodiesterase. Proc Natl Acad Sci USA 90:11970-11974
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11970-11974
-
-
Pillai, R.1
Kytle, K.2
Reyes, A.3
Colicelli, J.4
-
37
-
-
0027454556
-
A family of human phosphodiesterases homologues to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs
-
Bolger G, Michaeli T, Martins T, St. John T, Steiner B, Rodgers L, Riggs M, Wigler M, Ferguson K (1993) A family of human phosphodiesterases homologues to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs. Mol Cell Biol 13: 6558-6571
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6558-6571
-
-
Bolger, G.1
Michaeli, T.2
Martins, T.3
St John, T.4
Steiner, B.5
Rodgers, L.6
Riggs, M.7
Wigler, M.8
Ferguson, K.9
-
38
-
-
0028140251
-
Structure of two rat genes coding for closely related rolipram-sensitive cAMP phosphodiesterases
-
Monaco L, Vicini E, Conti M (1994) Structure of two rat genes coding for closely related rolipram-sensitive cAMP phosphodiesterases. J Biol Chem 269:347-357
-
(1994)
J Biol Chem
, vol.269
, pp. 347-357
-
-
Monaco, L.1
Vicini, E.2
Conti, M.3
-
40
-
-
0027339578
-
m, rolipram-sensitive, cAMP-specific phosphodiesterase from human brain
-
m, rolipram-sensitive, cAMP-specific phosphodiesterase from human brain. J Biol Chem 268: 6470-6476
-
(1993)
J Biol Chem
, vol.268
, pp. 6470-6476
-
-
McLaughlin, M.M.1
Cieslinski, L.B.2
Burman, M.3
Torphy, T.J.4
Livi, G.P.5
-
41
-
-
0027244894
-
The cDNA of a human lymphocyte cyclic-AMP phosphodiesterase (PDE IV) reveals a multigene family
-
Obernolte R, Bhakta S, Alvarez R, Bach C, Zuppan P, Mulkins M, Jarnagin K, Shelton ER (1993) The cDNA of a human lymphocyte cyclic-AMP phosphodiesterase (PDE IV) reveals a multigene family. Gene 129:239-247
-
(1993)
Gene
, vol.129
, pp. 239-247
-
-
Obernolte, R.1
Bhakta, S.2
Alvarez, R.3
Bach, C.4
Zuppan, P.5
Mulkins, M.6
Jarnagin, K.7
Shelton, E.R.8
-
42
-
-
0024405251
-
Molecular cloning of rat homologues of the Drosophila melanogaster dunce cAMP phosphodiesterase: Evidence for a family of genes
-
Swinnen JV, Joseph DR, Conti M (1989) Molecular cloning of rat homologues of the Drosophila melanogaster dunce cAMP phosphodiesterase: evidence for a family of genes. Proc Natl Acad Sci USA 86:5325-5329
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 5325-5329
-
-
Swinnen, J.V.1
Joseph, D.R.2
Conti, M.3
-
43
-
-
0344531201
-
The mRNA encoding a high-affinity cAMP phosphodiesterase is regulated by hormones and cAMP
-
Swinnen JV, Joseph DR, Conti M (1989) The mRNA encoding a high-affinity cAMP phosphodiesterase is regulated by hormones and cAMP. Proc Natl Acad Sci USA 86:197-8201
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 197-8201
-
-
Swinnen, J.V.1
Joseph, D.R.2
Conti, M.3
-
44
-
-
0025370222
-
m, rolipram-sensitive cyclic AMP phosphodiesterase
-
m, rolipram-sensitive cyclic AMP phosphodiesterase. Mol Cell Biol 10:2678-2686
-
(1990)
Mol Cell Biol
, vol.10
, pp. 2678-2686
-
-
Livi, G.P.1
Kmetz, P.2
McHale, M.M.3
Cieslinski, L.B.4
Sathe, G.M.5
Taylor, D.P.6
Davis, R.L.7
Torphy, T.J.8
Balcarek, J.M.9
-
45
-
-
0028919271
-
Molecular cloning and functional expression in yeast of a human cAMP-specific phosphodiesterase subtype (PDE IV-C)
-
Engels P, Sullivan M, Mueller T, Luebbert H (1995) Molecular cloning and functional expression in yeast of a human cAMP-specific phosphodiesterase subtype (PDE IV-C). FEBS Lett 358:305-310
-
(1995)
FEBS Lett
, vol.358
, pp. 305-310
-
-
Engels, P.1
Sullivan, M.2
Mueller, T.3
Luebbert, H.4
-
46
-
-
0028036970
-
2) in brain: Selective localisation in membrane and cytosolic compartments and differential expression in various brain regions
-
2) in brain: selective localisation in membrane and cytosolic compartments and differential expression in various brain regions. Biochem J 304:399-406
-
(1994)
Biochem J
, vol.304
, pp. 399-406
-
-
Lobhan, M.1
Shakur, Y.2
Beattie, J.3
Housley, M.D.4
-
47
-
-
84914555600
-
Sensitivity of a cAMP PDE to rolipram in different organs
-
Heilmeyer LMG (ed) NATO AS Series A New York. London
-
Schneider HH, Pahlke G, Schmiechen R (1997) Sensitivity of a cAMP PDE to rolipram in different organs. In: Heilmeyer LMG (ed) Signal transduction and protein phosphorylation. NATO AS Series A New York. London, vol 135, pp 81-85
-
(1997)
Signal Transduction and Protein Phosphorylation
, vol.135
, pp. 81-85
-
-
Schneider, H.H.1
Pahlke, G.2
Schmiechen, R.3
-
49
-
-
0028998011
-
Regulation of distinct cyclic AMP-specific phosphodiesterase (phosphodiesterase type 4) isozymes in human monocytic cells
-
Vergehse MW, McConnell RT, Lenhard JM, Hamacher L, Jin SLC (1995) Regulation of distinct cyclic AMP-specific phosphodiesterase (phosphodiesterase type 4) isozymes in human monocytic cells. Mol Pharmacol 47:1164-1171
-
(1995)
Mol Pharmacol
, vol.47
, pp. 1164-1171
-
-
Vergehse, M.W.1
McConnell, R.T.2
Lenhard, J.M.3
Hamacher, L.4
Slc, J.5
-
50
-
-
0001227355
-
Cardiac phosphodiesterases and the functional effects of selective inhibitors
-
Beavo J, Houslay MD (eds) Wiley, Chichester
-
Reeves ML, England PJ (1990) Cardiac phosphodiesterases and the functional effects of selective inhibitors. In: Beavo J, Houslay MD (eds) Cyclic nucleotide phosphodiesterases: structure, regulation and drug action. Wiley, vol 2. Chichester, pp 299-316
-
(1990)
Cyclic Nucleotide Phosphodiesterases: Structure, Regulation and Drug Action
, vol.2
, pp. 299-316
-
-
Reeves, M.L.1
England, P.J.2
-
51
-
-
0022460551
-
Multiple molecular forms of cyclic nucleotide phosphodiesterase in cardiac and smooth muscle and in platelets, Isolation, characterization, and effects of various reference phosphodiesterase inhibitors and cardiotonic agents
-
Weishaar RE, Burrows SD, Kobylarz DC, Quade MM, Evans DB (1986) Multiple molecular forms of cyclic nucleotide phosphodiesterase in cardiac and smooth muscle and in platelets, Isolation, characterization, and effects of various reference phosphodiesterase inhibitors and cardiotonic agents. Biochem Pharmacol 35:787-800
-
(1986)
Biochem Pharmacol
, vol.35
, pp. 787-800
-
-
Weishaar, R.E.1
Burrows, S.D.2
Kobylarz, D.C.3
Quade, M.M.4
Evans, D.B.5
-
52
-
-
0028171498
-
Anti-inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor
-
Raeburn D, Underwood SL, Lewis SA, Woodman VR, Battram CH, Tomkinson A, Sharma S, Jordan R, Souness JE, Webber SE, Karlsson JA (1994) Anti-inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor. Br J Pharmacol 113:1423-1431
-
(1994)
Br J Pharmacol
, vol.113
, pp. 1423-1431
-
-
Raeburn, D.1
Underwood, S.L.2
Lewis, S.A.3
Woodman, V.R.4
Battram, C.H.5
Tomkinson, A.6
Sharma, S.7
Jordan, R.8
Souness, J.E.9
Webber, S.E.10
Karlsson, J.A.11
-
53
-
-
0026741623
-
Human bronchial cyclic nucleotide phosphodiesterase isozymes: Biochemical and pharmacological analysis using selective inhibitors
-
De Boer J, Philpott AJ, VanAmsterdam RGM, Shahid M, Zaagsma J, Nicholson CD (1991) Human bronchial cyclic nucleotide phosphodiesterase isozymes: biochemical and pharmacological analysis using selective inhibitors. Br J Pharmacol 106:1028-1034
-
(1991)
Br J Pharmacol
, vol.106
, pp. 1028-1034
-
-
De Boer, J.1
Philpott, A.J.2
VanAmsterdam, R.G.M.3
Shahid, M.4
Zaagsma, J.5
Nicholson, C.D.6
-
54
-
-
0027287873
-
Effects of rolipram and siguazodan on the human isolated bronchus and their interaction with isoprenaline and sodium nitroprusside
-
Qian Y, Naline E, Karlsson J-A, Raeburn D, Ad Venier C (1993) Effects of rolipram and siguazodan on the human isolated bronchus and their interaction with isoprenaline and sodium nitroprusside. Br J Pharmacol 109:774-778
-
(1993)
Br J Pharmacol
, vol.109
, pp. 774-778
-
-
Qian, Y.1
Naline, E.2
Karlsson, J.-A.3
Raeburn, D.4
Ad Venier, C.5
-
56
-
-
0028134973
-
Characterization of cAMP-dependent inhibition or LPS-induced TNF α production by rolipram, a specific phosphodiesterase IV (PDF IV) inhibitor
-
Prabhakar U, Lipshutz D, O'Leary Bartus J, Slivjak MJ, Smith III EF, Lee JC, Esser KM (1994) Characterization of cAMP-dependent inhibition or LPS-induced TNF α production by rolipram, a specific phosphodiesterase IV (PDF IV) inhibitor. Int J Ummunopharmac 16:805-816
-
(1994)
Int J Ummunopharmac
, vol.16
, pp. 805-816
-
-
Prabhakar, U.1
Lipshutz, D.2
O'Leary Bartus, J.3
Slivjak, M.J.4
Smith III, E.F.5
Lee, J.C.6
Esser, K.M.7
-
57
-
-
0024354221
-
Regulation of tumor necrosis factor expression in a macrophage-like cell line by lipopolysaccaride and cyclic AMP
-
Taffet SM, Singhel KJ, Overholtzer JF, Shurtleff SA, (1989) Regulation of tumor necrosis factor expression in a macrophage-like cell line by lipopolysaccaride and cyclic AMP. Cell Immunol 120:291-300
-
(1989)
Cell Immunol
, vol.120
, pp. 291-300
-
-
Taffet, S.M.1
Singhel, K.J.2
Overholtzer, J.F.3
Shurtleff, S.A.4
-
58
-
-
0023688206
-
Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxifylline
-
Stricter RM, Remick DG, Ward PA, Spengler RN, Lynch JP, Larrick J, Kunkel SL (1988) Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxifylline. Biochem Biophys Res Comm 155:1230-1236
-
(1988)
Biochem Biophys Res Comm
, vol.155
, pp. 1230-1236
-
-
Stricter, R.M.1
Remick, D.G.2
Ward, P.A.3
Spengler, R.N.4
Lynch, J.P.5
Larrick, J.6
Kunkel, S.L.7
-
59
-
-
0028843980
-
Cyclic nucleotide phosphodiesterase type IV participates in the regulation of IL-10 and in the subsequent inhibition of TNF-α and IL-6 release by endotoxin stimulated macrophages
-
Kambayashi T, Jacob CO, Zhou D, Mazurek N, Fong M, Strassmann G (1995) Cyclic nucleotide phosphodiesterase type IV participates in the regulation of IL-10 and in the subsequent inhibition of TNF-α and IL-6 release by endotoxin stimulated macrophages. J Immunol 155:4909-4916
-
(1995)
J Immunol
, vol.155
, pp. 4909-4916
-
-
Kambayashi, T.1
Jacob, C.O.2
Zhou, D.3
Mazurek, N.4
Fong, M.5
Strassmann, G.6
-
60
-
-
0029150012
-
Self-antigen-induced Th2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice
-
Cua DJ, Hinton DR, Stohlman SA (1995) Self-antigen-induced Th2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice. J Immunol 155:4052-4059
-
(1995)
J Immunol
, vol.155
, pp. 4052-4059
-
-
Cua, D.J.1
Hinton, D.R.2
Stohlman, S.A.3
-
61
-
-
0027141832
-
Encephalitogenic Th1 cells are inhibited by Th2 cells with related peptide specificity: Roles of interleukin (IL)-4 and -10
-
van der Veen R, Stohlman SA (1993) Encephalitogenic Th1 cells are inhibited by Th2 cells with related peptide specificity: Roles of interleukin (IL)-4 and -10. J Neuroimmunol 48: 213-220
-
(1993)
J Neuroimmunol
, vol.48
, pp. 213-220
-
-
Van Der Veen, R.1
Stohlman, S.A.2
-
62
-
-
0027529932
-
Surface expression of α integrin by CD4 T cells is required for their entry into brain parenchyma
-
Baron JL, Madri JA, Ruddle NH, Hashim G, Janeway Jr, CA (1993) Surface expression of α integrin by CD4 T cells is required for their entry into brain parenchyma. J Exp Med 177: 57-68
-
(1993)
J Exp Med
, vol.177
, pp. 57-68
-
-
Baron, J.L.1
Madri, J.A.2
Ruddle, N.H.3
Hashim, G.4
Janeway Jr., C.A.5
-
64
-
-
0028116618
-
Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease
-
Racke MK, Bonomo A, Scott DE, Cannella B, Levine A, Raine CS, Shevach EM, Roecken M (1994) Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. J Exp Med 180:1961-1966
-
(1994)
J Exp Med
, vol.180
, pp. 1961-1966
-
-
Racke, M.K.1
Bonomo, A.2
Scott, D.E.3
Cannella, B.4
Levine, A.5
Raine, C.S.6
Shevach, E.M.7
Roecken, M.8
-
65
-
-
0025667152
-
cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells
-
Novak TJ, Rothenberg EV, (1990) cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells. Proc Natl Acad Sci USA 87:9353-9357
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 9353-9357
-
-
Novak, T.J.1
Rothenberg, E.V.2
-
66
-
-
0025338731
-
Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor mediated activation
-
Munoz E, Zubiaga AM, Merrow M, Sauter NP, Huber BT (1990) Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor mediated activation. J Exp Med 172: 95-103
-
(1990)
J Exp Med
, vol.172
, pp. 95-103
-
-
Munoz, E.1
Zubiaga, A.M.2
Merrow, M.3
Sauter, N.P.4
Huber, B.T.5
-
67
-
-
0027273042
-
Phosphodiesterase inhibitor pentoxifylline, a selective suppressor of T helper type 1-but not type 2-associated lymphokine production, prevents induction of experimental autoimmune encephalomyelitis in Lewis rats
-
Rott O, Cash E, Fleischer B (1993) Phosphodiesterase inhibitor pentoxifylline, a selective suppressor of T helper type 1-but not type 2-associated lymphokine production, prevents induction of experimental autoimmune encephalomyelitis in Lewis rats. Eur J Immunol 23:1745-1751
-
(1993)
Eur J Immunol
, vol.23
, pp. 1745-1751
-
-
Rott, O.1
Cash, E.2
Fleischer, B.3
-
68
-
-
0028931690
-
Active and passivly induced experimental autoimmune encephalomyelitis in common marmosets: A new model for multiple sclerosis
-
Massacesi L, Genain CP, Lee-Parritz D, Canfield D, Hauser SL (1995) Active and passivly induced experimental autoimmune encephalomyelitis in common marmosets: a new model for multiple sclerosis. Ann Neurol 37:519-530
-
(1995)
Ann Neurol
, vol.37
, pp. 519-530
-
-
Massacesi, L.1
Genain, C.P.2
Lee-Parritz, D.3
Canfield, D.4
Hauser, S.L.5
-
70
-
-
0022614962
-
Determination of the number of endothelial cells in culture using an acid phosphatase assay
-
Conolly DT, Knight MB, Harakas NK, Wittwer AJ, Feder J (1986) Determination of the number of endothelial cells in culture using an acid phosphatase assay. Anal Biochem 152: 136-140
-
(1986)
Anal Biochem
, vol.152
, pp. 136-140
-
-
Conolly, D.T.1
Knight, M.B.2
Harakas, N.K.3
Wittwer, A.J.4
Feder, J.5
|