A novel phosphodiesterase inhibitor, t-440: Possible management of eosinophilic inflammation by down-regulation of lnterleukin-5 production

International Archives of Allergy and Immunology

Volumn 111, Issue 1, 1996, Pages 16-18

  Kaminuma, Osamu ^a,b   Mori, Akio ^a   Suko, Matsunobu ^a   Nishizaki, Yoko ^a   Kikkawa, Hideo ^b   Ikezawa, Katsuo ^b   Okudaira, Hirokazu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Asthma; Atopy; CD4+ T cell; Eosinophil; Interleukin 5; Intracellular cyclic AMP; Phosphodiesterase inhibitor

Indexed keywords

BUCLADESINE; INTERLEUKIN 5; PHOSPHODIESTERASE INHIBITOR;

ALLERGIC ASTHMA; CONFERENCE PAPER; ENZYME ACTIVITY; EOSINOPHIL; HUMAN; INFLAMMATION; MONONUCLEAR CELL; PRIORITY JOURNAL;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ALLERGENS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ASTHMA; CD4-POSITIVE T-LYMPHOCYTES; CYCLIC AMP; DOWN-REGULATION; EOSINOPHILS; HUMANS; HYPERSENSITIVITY; INTERLEUKIN-5; MITES; NAPHTHALENES; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PYRIDONES;

EID: 0029785126     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000237407     Document Type: Article

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