Role of conserved histidines in catalytic activity and inhibitor binding of human recombinant phosphodiesterase 4A

Molecular Pharmacology

Volumn 51, Issue 6, 1997, Pages 999-1006

  Jacobitz, Susanne ^a   Ryan, M Dominic ^a   McLaughlin, Megan M ^a   Livi, George P ^b   DeWolf Jr , Walter E ^a   Torphy, Theodore J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; HISTIDINE; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; PICLAMILAST; RECOMBINANT PROTEIN; ROLIPRAM;

AMINO ACID SEQUENCE; ARTICLE; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME SUBSTRATE; GENETIC ENGINEERING; HYDROLYSIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; SECOND MESSENGER;

EID: 0030981608     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.51.6.999     Document Type: Article

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