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Volumn 282, Issue 3, 1997, Pages 1650-1657

Phosphodiesterase inhibition improves agonist-induced relaxation of hypertensive pulmonary arteries

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 8 BROMO CYCLIC AMP; BUCLADESINE; CILOMILAST; FORSKOLIN; ISOPRENALINE; MILRINONE; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; POTASSIUM CHLORIDE; ROLIPRAM; UNCLASSIFIED DRUG;

EID: 0030988865     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (58)

References (34)
  • 1
    • 0025963441 scopus 로고
    • Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia
    • ADNOT, S., RAFFESTIN, B., EDDAHIBI, S., BRAQUET, P. AND CHABRIER, P. E.: Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia. J. Clin. Invest. 87: 155-162, 1991.
    • (1991) J. Clin. Invest. , vol.87 , pp. 155-162
    • Adnot, S.1    Raffestin, B.2    Eddahibi, S.3    Braquet, P.4    Chabrier, P.E.5
  • 2
    • 0027991643 scopus 로고
    • Pharmacotherapy of chronic pulmonary arterial hypertension: Value and limitations. Part II: Secondary pulmonary hypertension
    • ALPERT, M. A., CONCANNON, M. D., MUKERJI, B. AND MUKERJI, V.: Pharmacotherapy of chronic pulmonary arterial hypertension: value and limitations. Part II: Secondary pulmonary hypertension [Review]. Angiology 45: 755-761, 1994.
    • (1994) Angiology , vol.45 , pp. 755-761
    • Alpert, M.A.1    Concannon, M.D.2    Mukerji, B.3    Mukerji, V.4
  • 3
    • 0028837592 scopus 로고
    • Future directions for research on diseases of the lung
    • AMERICAN THORACIC SOCIETY BOARD OF DIRECTORS: Future directions for research on diseases of the lung. Am. J. Respir. Crit. Care Med. 152: 1713-1735, 1995.
    • (1995) Am. J. Respir. Crit. Care Med. , vol.152 , pp. 1713-1735
  • 5
    • 0028802726 scopus 로고
    • Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms
    • BEAVO, J. A.: Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms. Physiol. Rev. 75: 725-748, 1995.
    • (1995) Physiol. Rev. , vol.75 , pp. 725-748
    • Beavo, J.A.1
  • 6
    • 0029009878 scopus 로고
    • Recent progress in understanding the hormonal regulation of phosphodiesterases
    • CONTI, M., NEMOZ, G., SETTE, C. AND VICINI, E.: Recent progress in understanding the hormonal regulation of phosphodiesterases [Review]. Endocr. Rev. 16: 370-389, 1995.
    • (1995) Endocr. Rev. , vol.16 , pp. 370-389
    • Conti, M.1    Nemoz, G.2    Sette, C.3    Vicini, E.4
  • 7
    • 0026785622 scopus 로고
    • Chronic hypoxia impairs soluble guanylyl cyclase-mediated pulmonary arterial relaxation in the rat
    • CRAWLEY, D. E., ZHAO, L., GIEMBYCZ, M. A., LIU, S., BARNES, P. J., WINTER, R. J. AND EVANS, T. W.: Chronic hypoxia impairs soluble guanylyl cyclase-mediated pulmonary arterial relaxation in the rat. Am. J. Physiol. 263: L325-L332, 1992.
    • (1992) Am. J. Physiol. , vol.263
    • Crawley, D.E.1    Zhao, L.2    Giembycz, M.A.3    Liu, S.4    Barnes, P.J.5    Winter, R.J.6    Evans, T.W.7
  • 8
    • 0028917848 scopus 로고
    • Role of prostacyclin in the treatment of primary pulmonary hypertension
    • CREMONA, G. AND HIGENBOTTAM, T.: Role of prostacyclin in the treatment of primary pulmonary hypertension [Review]. Am. J. Cardiol. 75: 67A-71A, 1995.
    • (1995) Am. J. Cardiol. , vol.75
    • Cremona, G.1    Higenbottam, T.2
  • 9
    • 0028074792 scopus 로고
    • Cyclic nucleotide phosphodiesterases in the human lung
    • DENT, G., MAGNUSSEN, H. AND RABE, K. F.: Cyclic nucleotide phosphodiesterases in the human lung [Review]. Lung 172: 129-146, 1994.
    • (1994) Lung , vol.172 , pp. 129-146
    • Dent, G.1    Magnussen, H.2    Rabe, K.F.3
  • 10
    • 0027339671 scopus 로고
    • 2 stimulated signal transduction in vascular smooth muscle
    • 2 stimulated signal transduction in vascular smooth muscle. J. Pharmacol. Exp. Ther. 265: 447-456, 1992.
    • (1992) J. Pharmacol. Exp. Ther. , vol.265 , pp. 447-456
    • Dorn II, G.W.1    Becker, M.W.2
  • 11
  • 12
    • 0028361796 scopus 로고
    • Pulmonary arterial smooth muscle contractility in hypoxia-induced pulmonary hypertension
    • GRIFFITH, S. L., RHOADES, R. A. AND PACKER, C. S.: Pulmonary arterial smooth muscle contractility in hypoxia-induced pulmonary hypertension. J. Appl. Physiol. 77: 406-414, 1994.
    • (1994) J. Appl. Physiol. , vol.77 , pp. 406-414
    • Griffith, S.L.1    Rhoades, R.A.2    Packer, C.S.3
  • 14
    • 0027377067 scopus 로고
    • Acute and chronic hypoxic pulmonary hypertension
    • HIGENBOTHAM, T. AND CREMONA, G.: Acute and chronic hypoxic pulmonary hypertension [Review]. Eur. Respir. J. 6: 1207-1212, 1993.
    • (1993) Eur. Respir. J. , vol.6 , pp. 1207-1212
    • Higenbotham, T.1    Cremona, G.2
  • 16
    • 0023627880 scopus 로고
    • In vitro vascular relaxation by new inotropic agents: Relationship to phosphodiesterase inhibition and cyclic nucleotides
    • KAUFFMAN, R. F., SCHENCK, K. W., UTTERBACK, B. G., CROWE, V. G. AND COHEN, M. L.: In vitro vascular relaxation by new inotropic agents: relationship to phosphodiesterase inhibition and cyclic nucleotides. J. Pharmacol. Exp. Ther. 242: 864-872, 1987.
    • (1987) J. Pharmacol. Exp. Ther. , vol.242 , pp. 864-872
    • Kauffman, R.F.1    Schenck, K.W.2    Utterback, B.G.3    Crowe, V.G.4    Cohen, M.L.5
  • 17
    • 0029069107 scopus 로고
    • Recent developments in the pathophysiology and treatment of persistent pulmonary hypertension of the newborn
    • KINSELLA, J. P. AND ABMAN, S. H.: Recent developments in the pathophysiology and treatment of persistent pulmonary hypertension of the newborn [Review]. J. Pediatr. 126: 853-864, 1995.
    • (1995) J. Pediatr. , vol.126 , pp. 853-864
    • Kinsella, J.P.1    Abman, S.H.2
  • 18
    • 0026056022 scopus 로고
    • Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors
    • KOMAS, N., LUGNIER, C. AND STOCLET, J.: Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors. Br. J. Pharmacol. 104: 495-503, 1991.
    • (1991) Br. J. Pharmacol. , vol.104 , pp. 495-503
    • Komas, N.1    Lugnier, C.2    Stoclet, J.3
  • 20
    • 0027527738 scopus 로고
    • Modulation of vascular cyclic nucleotide phosphodiesterases by cyclic GMP: Role in vasodilatation
    • LUGNIER, C. AND KOMAS, N.: Modulation of vascular cyclic nucleotide phosphodiesterases by cyclic GMP: role in vasodilatation. Eur. Heart J. 14: 141-148, 1993.
    • (1993) Eur. Heart J. , vol.14 , pp. 141-148
    • Lugnier, C.1    Komas, N.2
  • 21
    • 0028954867 scopus 로고
    • Inhaled nitric oxide therapy
    • LUNN, R. J.: Inhaled nitric oxide therapy [Review]. Mayo Clin. Proc. 70: 247-255, 1995.
    • (1995) Mayo Clin. Proc. , vol.70 , pp. 247-255
    • Lunn, R.J.1
  • 22
    • 0028349834 scopus 로고
    • Activation of cAMP-dependent protein kinase in rat aorta by cAMP analogs is not correlated with relaxation
    • MACDONALD, K. L. AND DIAMOND, J.: Activation of cAMP-dependent protein kinase in rat aorta by cAMP analogs is not correlated with relaxation. J. Vasc. Res. 31: 121-130, 1994.
    • (1994) J. Vasc. Res. , vol.31 , pp. 121-130
    • Macdonald, K.L.1    Diamond, J.2
  • 23
    • 0028070508 scopus 로고
    • Synergistic interactions between selective pharmacological inhibitors of phosphodiesterase isozyme families PDE III and PDE IV to attenuate proliferation of rat vascular smooth muscle cells
    • PAN, X., ARAUZ, E., KRZANOWSKI, J. J., FITZPATRICK, D. F. AND POLSON, J. B.: Synergistic interactions between selective pharmacological inhibitors of phosphodiesterase isozyme families PDE III and PDE IV to attenuate proliferation of rat vascular smooth muscle cells. Biochem. Pharmacol. 48: 827-835, 1994.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 827-835
    • Pan, X.1    Arauz, E.2    Krzanowski, J.J.3    Fitzpatrick, D.F.4    Polson, J.B.5
  • 25
    • 0029942933 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases and vascular smooth muscle. Chronic hypoxic pulmonary hypertension. Cell biology to pathophysiology
    • POLSON, J. B. AND STRADA, S. J.: Cyclic nucleotide phosphodiesterases and vascular smooth muscle. Chronic hypoxic pulmonary hypertension. Cell biology to pathophysiology [Review]. Annu. Rev. Pharmacol. Toxicol. 36: 403-427, 1996.
    • (1996) Annu. Rev. Pharmacol. Toxicol. , vol.36 , pp. 403-427
    • Polson, J.B.1    Strada, S.J.2
  • 26
    • 0028365921 scopus 로고
    • Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors
    • RABE, K. F., TENOR, H., DENT, G., SCHUDT, C., NAKASHIMA, M. AND MAGNUSSEN, H.: Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors. Am. J. Physiol. 266: L536-L543, 1994.
    • (1994) Am. J. Physiol. , vol.266
    • Rabe, K.F.1    Tenor, H.2    Dent, G.3    Schudt, C.4    Nakashima, M.5    Magnussen, H.6
  • 27
    • 0025864032 scopus 로고
    • Prostacyclin production and mediation of adenylate cyclase activity in the pulmonary artery. Alterations after prolonged hypoxia in the rat
    • SHAUL, P. W., KINANE, B., FARRAR, M. A., BUJA, L. M. AND MAGNESS, R. R.: Prostacyclin production and mediation of adenylate cyclase activity in the pulmonary artery. Alterations after prolonged hypoxia in the rat. J. Clin. Invest. 88: 447-455, 1991.
    • (1991) J. Clin. Invest. , vol.88 , pp. 447-455
    • Shaul, P.W.1    Kinane, B.2    Farrar, M.A.3    Buja, L.M.4    Magness, R.R.5
  • 28
    • 0025368835 scopus 로고
    • Effects of prolonged hypoxia on adenylate cyclase activity and beta-adrenergic receptors in pulmonary and systemic arteries of the rat
    • SHAUL, P. W., MUNTZ, K. H., DEBELTZ, D. AND BUJA, L. M.: Effects of prolonged hypoxia on adenylate cyclase activity and beta-adrenergic receptors in pulmonary and systemic arteries of the rat. Circ. Res. 66: 1526-1534, 1990.
    • (1990) Circ. Res. , vol.66 , pp. 1526-1534
    • Shaul, P.W.1    Muntz, K.H.2    Debeltz, D.3    Buja, L.M.4
  • 31
    • 0028827585 scopus 로고
    • Hypoxia inhibits L-arginine synthesis from L-citrulline in porcine pulmonary artery endothelial cells
    • SU, Y. AND BLOCK, E. R.: Hypoxia inhibits L-arginine synthesis from L-citrulline in porcine pulmonary artery endothelial cells. Am. J. Physiol. 269: L581-L587, 1995.
    • (1995) Am. J. Physiol. , vol.269
    • Su, Y.1    Block, E.R.2
  • 32
    • 0027283557 scopus 로고
    • Molecular cloning of the rat adipocyte hormone-sensitive cyclic GMP-inhibited cyclic nucleotide phosphodiesterase
    • TAIRA, M., HOCKMAN, S. C., CALVO, J. C., BELFRAGE,. AND MANGANIELLO, V. C.: Molecular cloning of the rat adipocyte hormone-sensitive cyclic GMP-inhibited cyclic nucleotide phosphodiesterase. J. Biol. Chem. 268: 18573-18579, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 18573-18579
    • Taira, M.1    Hockman, S.C.2    Calvo, J.C.3    Belfrage4    Manganiello, V.C.5
  • 33
    • 0028304046 scopus 로고
    • Chronic hypoxic pulmonary hypertension. Cell biology to pathophysiology
    • VENDER, R. L.: Chronic hypoxic pulmonary hypertension. Cell biology to pathophysiology. Chest 106: 236-243, 1994.
    • (1994) Chest , vol.106 , pp. 236-243
    • Vender, R.L.1
  • 34
    • 0026580581 scopus 로고
    • Responses to vasodilator drugs on pulmonary artery preparations from pulmonary hypertensive rats
    • WANSTALL, J. C. AND O'DONNELL, S. R.: Responses to vasodilator drugs on pulmonary artery preparations from pulmonary hypertensive rats. Br. J. Pharmacol. 105: 152-158, 1992.
    • (1992) Br. J. Pharmacol. , vol.105 , pp. 152-158
    • Wanstall, J.C.1    O'Donnell, S.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.