-
1
-
-
0017831463
-
Ricin and ricinus agglutinin, toxic lectins from castor bean
-
Olsnes S. 1978. Ricin and ricinus agglutinin, toxic lectins from castor bean. Methods Enzymol 50:330-335.
-
(1978)
Methods Enzymol
, vol.50
, pp. 330-335
-
-
Olsnes, S.1
-
2
-
-
0022931519
-
Purification of ricin A1, A2, and B chains and characterization of their toxicity
-
Fulton RJ, Blakey DC, Knowles PP, Uhr JW, Thorpe PE, and Vitetta ES. 1986. Purification of ricin A1, A2, and B chains and characterization of their toxicity. J Biol Chem 261:5314-5319.
-
(1986)
J Biol Chem
, vol.261
, pp. 5314-5319
-
-
Fulton, R.J.1
Blakey, D.C.2
Knowles, P.P.3
Uhr, J.W.4
Thorpe, P.E.5
Vitetta, E.S.6
-
4
-
-
0018908163
-
Purification and physicochemical properties of ricins and agglutinins from Ricinus communis
-
Thomas TS and Li Steven SL. 1980. Purification and physicochemical properties of ricins and agglutinins from Ricinus communis. Eur J Biochem 105:453-459.
-
(1980)
Eur J Biochem
, vol.105
, pp. 453-459
-
-
Thomas, T.S.1
Li Steven, S.L.2
-
5
-
-
0002954612
-
Ricin toxin
-
Zajtchuk R and Bellamy RF (eds.), Borden Institute Books, Washington, DC
-
Franz D and Jaax N. 1997. Ricin toxin. In Zajtchuk R and Bellamy RF (eds.), Textbook of Military Medicine. pp. 631-642, Borden Institute Books, Washington, DC.
-
(1997)
Textbook of Military Medicine
, pp. 631-642
-
-
Franz, D.1
Jaax, N.2
-
7
-
-
0036200534
-
Public health assessment of potential biological terrorism agents
-
Rotz LD, Khan AS, Lillibridge SR, Ostroff SM, and Hughes JM. 2002. Public health assessment of potential biological terrorism agents. Emerg Infect Dis 8:225-230.
-
(2002)
Emerg Infect Dis
, vol.8
, pp. 225-230
-
-
Rotz, L.D.1
Khan, A.S.2
Lillibridge, S.R.3
Ostroff, S.M.4
Hughes, J.M.5
-
8
-
-
80054984615
-
Ricinus communis intoxications in human and veterinary medicine-A summary of real cases
-
Worbs S, Kohler K, Pauly D, Avondet MA, Schaer M, Dorner MB, and Dorner BG. 2011. Ricinus communis intoxications in human and veterinary medicine-A summary of real cases. Toxins (Basel) 3:1332-1372.
-
(2011)
Toxins (Basel)
, vol.3
, pp. 1332-1372
-
-
Worbs, S.1
Kohler, K.2
Pauly, D.3
Avondet, M.A.4
Schaer, M.5
Dorner, M.B.6
Dorner, B.G.7
-
9
-
-
82255165405
-
Understanding ricin from a defensive viewpoint
-
Griffiths GD. 2011. Understanding ricin from a defensive viewpoint. Toxins (Basel) 3:1373-1392.
-
(2011)
Toxins (Basel)
, vol.3
, pp. 1373-1392
-
-
Griffiths, G.D.1
-
10
-
-
84857880542
-
How ricin and shiga toxin reach the cytosol of target cells: Retrotranslocation from the endoplasmic reticulum
-
Spooner RA and Lord JM. 2012. How ricin and shiga toxin reach the cytosol of target cells: Retrotranslocation from the endoplasmic reticulum. Curr Top Microbiol Immunol 357:19-40.
-
(2012)
Curr Top Microbiol Immunol
, vol.357
, pp. 19-40
-
-
Spooner, R.A.1
Lord, J.M.2
-
11
-
-
84857826373
-
The induction of apoptosis by shiga toxins and ricin
-
Tesh VL. 2012. The induction of apoptosis by shiga toxins and ricin. Curr Top Microbiol Immunol 357:137-178.
-
(2012)
Curr Top Microbiol Immunol
, vol.357
, pp. 137-178
-
-
Tesh, V.L.1
-
12
-
-
84863285459
-
Interaction of ricin and shiga toxins with ribosomes
-
Tumer NE and Li XP. 2012. Interaction of ricin and shiga toxins with ribosomes. Curr Top Microbiol Immunol 357:1-18.
-
(2012)
Curr Top Microbiol Immunol
, vol.357
, pp. 1-18
-
-
Tumer, N.E.1
Li, X.P.2
-
13
-
-
84857819735
-
Animal models of ricin toxicosis
-
Roy CJ, Song K, Sivasubramani SK, Gardner DJ, and Pincus SH. 2012. Animal models of ricin toxicosis. Curr Top Microbiol Immunol 357:243-257.
-
(2012)
Curr Top Microbiol Immunol
, vol.357
, pp. 243-257
-
-
Roy, C.J.1
Song, K.2
Sivasubramani, S.K.3
Gardner, D.J.4
Pincus, S.H.5
-
14
-
-
84857812737
-
Immunity to ricin: Fundamental insights into toxin-antibody interactions
-
O’Hara JM, Yermakova A, and Mantis NJ. 2012. Immunity to ricin: Fundamental insights into toxin-antibody interactions. Curr Top Microbiol Immunol 357:209-241.
-
(2012)
Curr Top Microbiol Immunol
, vol.357
, pp. 209-241
-
-
O’Hara, J.M.1
Yermakova, A.2
Mantis, N.J.3
-
17
-
-
77956656511
-
Draft genome sequence of the oilseed species Ricinus communis
-
Chan AP, Crabtree J, Zhao Q, Lorenzi H, Orvis J, Puiu D, Melake-Berhan A et al. 2010. Draft genome sequence of the oilseed species Ricinus communis. Nat Biotechnol 28:951-956.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 951-956
-
-
Chan, A.P.1
Crabtree, J.2
Zhao, Q.3
Lorenzi, H.4
Orvis, J.5
Puiu, D.6
Melake-Berhan, A.7
-
18
-
-
77649322025
-
Single nucleotide polymorphisms for assessing genetic diversity in castor bean (Ricinus communis)
-
Foster JT, Allan GJ, Chan AP, Rabinowicz PD, Ravel J, Jackson PJ, and Keim P. 2010. Single nucleotide polymorphisms for assessing genetic diversity in castor bean (Ricinus communis). BMC Plant Biol 10:13.
-
(2010)
BMC Plant Biol
, vol.10
, pp. 13
-
-
Foster, J.T.1
Allan, G.J.2
Chan, A.P.3
Rabinowicz, P.D.4
Ravel, J.5
Jackson, P.J.6
Keim, P.7
-
19
-
-
79960033513
-
Castor bean organelle genome sequencing and worldwide genetic diversity analysis
-
Rivarola M, Foster JT, Chan AP, Williams AL, Rice DW, Liu X, Melake-Berhan A et al. 2011. Castor bean organelle genome sequencing and worldwide genetic diversity analysis. PLoS One 6:e21743.
-
(2011)
PLoS One
, vol.6
-
-
Rivarola, M.1
Foster, J.T.2
Chan, A.P.3
Williams, A.L.4
Rice, D.W.5
Liu, X.6
Melake-Berhan, A.7
-
20
-
-
37349054422
-
Final report on the safety assessment of Ricinus communis (castor) seed oil, hydrogenated castor oil, glyceryl ricinoleate, glyceryl ricinoleate se, ricinoleic acid, potassium ricinoleate, sodium ricinoleate, zinc ricinoleate, cetyl ricinoleate, ethyl ricinoleate, glycol ricinoleate, isopropyl ricinoleate, methyl ricinoleate, and octyldodecyl ricinoleate
-
2007. Final report on the safety assessment of Ricinus communis (castor) seed oil, hydrogenated castor oil, glyceryl ricinoleate, glyceryl ricinoleate se, ricinoleic acid, potassium ricinoleate, sodium ricinoleate, zinc ricinoleate, cetyl ricinoleate, ethyl ricinoleate, glycol ricinoleate, isopropyl ricinoleate, methyl ricinoleate, and octyldodecyl ricinoleate. Int J Toxicol 26(Suppl 3):31-77.
-
(2007)
Int J Toxicol
, vol.26
, pp. 31-77
-
-
-
22
-
-
0022425912
-
Nucleotide sequence of cloned cDNA coding for preproricin
-
Lamb FI, Roberts LM, and Lord JM. 1985. Nucleotide sequence of cloned cDNA coding for preproricin. Eur J Biochem 148:265-270.
-
(1985)
Eur J Biochem
, vol.148
, pp. 265-270
-
-
Lamb, F.I.1
Roberts, L.M.2
Lord, J.M.3
-
23
-
-
0021925967
-
Precursors of ricin and Ricinus communis agglutinin. Glycosylation and processing during synthesis and intracellular transport
-
Lord JM. 1985. Precursors of ricin and Ricinus communis agglutinin. Glycosylation and processing during synthesis and intracellular transport. Eur J Biochem 146:411-416.
-
(1985)
Eur J Biochem
, vol.146
, pp. 411-416
-
-
Lord, J.M.1
-
24
-
-
27844451115
-
Pathways for protein transport to seed storage vacuoles
-
Jolliffe NA, Craddock CP, and Frigerio L. 2005. Pathways for protein transport to seed storage vacuoles. Biochem Soc Trans 33:1016-1018.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 1016-1018
-
-
Jolliffe, N.A.1
Craddock, C.P.2
Frigerio, L.3
-
26
-
-
0023654540
-
The three-dimensional structure of ricin at 2.8 Å
-
Montfort W, Villafranca JE, Monzingo AF, Ernst SR, Katzin B, Rutenber E, Xuong NH, Hamlin R, and Robertus JD. 1987. The three-dimensional structure of ricin at 2.8 Å. J Biol Chem 262:5398-5403.
-
(1987)
J Biol Chem
, vol.262
, pp. 5398-5403
-
-
Montfort, W.1
Villafranca, J.E.2
Monzingo, A.F.3
Ernst, S.R.4
Katzin, B.5
Rutenber, E.6
Xuong, N.H.7
Hamlin, R.8
Robertus, J.D.9
-
27
-
-
0023104201
-
Crystallization of ricin A chain obtained from a cloned gene expressed in Escherichia coli
-
Robertus JD, Piatak M, Ferris R, and Houston LL. 1987. Crystallization of ricin A chain obtained from a cloned gene expressed in Escherichia coli. J Biol Chem 262:19-20.
-
(1987)
J Biol Chem
, vol.262
, pp. 19-20
-
-
Robertus, J.D.1
Piatak, M.2
Ferris, R.3
Houston, L.L.4
-
28
-
-
0025996872
-
Crystallographic refinement of ricin to 2.5 Å
-
Rutenber E, Katzin BJ, Ernst S, Collins EJ, Mlsna D, Ready MP, and Robertus JD. 1991. Crystallographic refinement of ricin to 2.5 Å. Proteins 10:240-250.
-
(1991)
Proteins
, vol.10
, pp. 240-250
-
-
Rutenber, E.1
Katzin, B.J.2
Ernst, S.3
Collins, E.J.4
Mlsna, D.5
Ready, M.P.6
Robertus, J.D.7
-
29
-
-
0016696693
-
Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains
-
Olsnes S, Fernandez-Puentes C, Carrasco L, and Vazquez D. 1975. Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains. Eur J Biochem 60:281-288.
-
(1975)
Eur J Biochem
, vol.60
, pp. 281-288
-
-
Olsnes, S.1
Fernandez-Puentes, C.2
Carrasco, L.3
Vazquez, D.4
-
30
-
-
0023664263
-
The mechanism of action of ricin and related toxins on eukaryotic ribosomes
-
Endo Y, Mitsui K, Motizuki M, and Tsurugi K. 1987. The mechanism of action of ricin and related toxins on eukaryotic ribosomes. J Biol Chem 262:5908-5912.
-
(1987)
J Biol Chem
, vol.262
, pp. 5908-5912
-
-
Endo, Y.1
Mitsui, K.2
Motizuki, M.3
Tsurugi, K.4
-
31
-
-
0023219950
-
RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes
-
Endo Y and Tsurugi K. 1987. RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes. J Biol Chem 262:8128-8130.
-
(1987)
J Biol Chem
, vol.262
, pp. 8128-8130
-
-
Endo, Y.1
Tsurugi, K.2
-
32
-
-
0023927967
-
Structures of sugar chains of ricin D
-
Kimura Y, Hase S, Kobayashi Y, Kyogoku Y, Ikenaka T, and Funatsu G. 1988. Structures of sugar chains of ricin D. J Biochem (Tokyo) 103:944-949.
-
(1988)
J Biochem (Tokyo)
, vol.103
, pp. 944-949
-
-
Kimura, Y.1
Hase, S.2
Kobayashi, Y.3
Kyogoku, Y.4
Ikenaka, T.5
Funatsu, G.6
-
33
-
-
0020459630
-
Radioimmunoassay of ricin A- and B-chains applied to samples of ricin A-chain prepared by chromatofocusing and by DEAE Bio-Gel A chromatography
-
Ramakrishnan S, Eagle MR, and Houston LL. 1982. Radioimmunoassay of ricin A- and B-chains applied to samples of ricin A-chain prepared by chromatofocusing and by DEAE Bio-Gel A chromatography. Biochim Biophys Acta 719:341-348.
-
(1982)
Biochim Biophys Acta
, vol.719
, pp. 341-348
-
-
Ramakrishnan, S.1
Eagle, M.R.2
Houston, L.L.3
-
34
-
-
0022428446
-
The removal of carbohydrates from ricin with endoglycosidases H, F and D and alpha-mannosidase
-
Foxwell BM, Donovan TA, Thorpe PE, and Wilson G. 1985. The removal of carbohydrates from ricin with endoglycosidases H, F and D and alpha-mannosidase. Biochim Biophys Acta 840:193-203.
-
(1985)
Biochim Biophys Acta
, vol.840
, pp. 193-203
-
-
Foxwell, B.M.1
Donovan, T.A.2
Thorpe, P.E.3
Wilson, G.4
-
35
-
-
0032905566
-
Prediction of a conserved, neutralizing epitope in ribosome-inactivating proteins
-
Lebeda FJ and Olson MA. 1999. Prediction of a conserved, neutralizing epitope in ribosome-inactivating proteins. Int J Biol Macromol 24:19-26.
-
(1999)
Int J Biol Macromol
, vol.24
, pp. 19-26
-
-
Lebeda, F.J.1
Olson, M.A.2
-
36
-
-
0023010495
-
Ricin subunit association. Thermodynamics and the role of the disulfide bond in toxicity
-
Lewis MS and Youle RJ. 1986. Ricin subunit association. Thermodynamics and the role of the disulfide bond in toxicity. J Biol Chem 261:11571-11577.
-
(1986)
J Biol Chem
, vol.261
, pp. 11571-11577
-
-
Lewis, M.S.1
Youle, R.J.2
-
37
-
-
0019432633
-
Ricin B chain is a product of gene duplication
-
Villafranca JE and Robertus JD. 1981. Ricin B chain is a product of gene duplication. J Biol Chem 256:554-556.
-
(1981)
J Biol Chem
, vol.256
, pp. 554-556
-
-
Villafranca, J.E.1
Robertus, J.D.2
-
38
-
-
33745395593
-
EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol
-
Slominska-Wojewodzka M, Gregers TF, Walchli S, and Sandvig K. 2006. EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol. Mol Biol Cell 17:1664-1675.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 1664-1675
-
-
Slominska-Wojewodzka, M.1
Gregers, T.F.2
Walchli, S.3
Sandvig, K.4
-
39
-
-
0025986485
-
Mutational analysis of the galactose binding ability of recombinant ricin B chain
-
Wales R, Richardson PT, Roberts LM, Woodland HR, and Lord JM. 1991. Mutational analysis of the galactose binding ability of recombinant ricin B chain. J Biol Chem 266:19172-19179.
-
(1991)
J Biol Chem
, vol.266
, pp. 19172-19179
-
-
Wales, R.1
Richardson, P.T.2
Roberts, L.M.3
Woodland, H.R.4
Lord, J.M.5
-
40
-
-
0030941217
-
Restoration of lectin activity to a non-glycosylated ricin B chain mutant by the introduction of a novel N-glycosylation site
-
Zhan J, de Sousa M, Chaddock JA, Roberts LM, and Lord JM. 1997. Restoration of lectin activity to a non-glycosylated ricin B chain mutant by the introduction of a novel N-glycosylation site. FEBS Lett 407:271-274.
-
(1997)
FEBS Lett
, vol.407
, pp. 271-274
-
-
Zhan, J.1
de Sousa, M.2
Chaddock, J.A.3
Roberts, L.M.4
Lord, J.M.5
-
42
-
-
0022982241
-
Mannose receptor-mediated uptake of ricin toxin and ricin A chain by macrophages. Multiple intracellular pathways for a chain translocation
-
Simmons BM, Stahl PD, and Russell JH. 1986. Mannose receptor-mediated uptake of ricin toxin and ricin A chain by macrophages. Multiple intracellular pathways for a chain translocation. J Biol Chem 261:7912-7920.
-
(1986)
J Biol Chem
, vol.261
, pp. 7912-7920
-
-
Simmons, B.M.1
Stahl, P.D.2
Russell, J.H.3
-
43
-
-
77954144429
-
R-type lectins
-
Varki A, Cummings R, Esko J, Freeze H, Stanley P, Bertozzi C, Hart G, and Etzler M (eds.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Cummings R and Etzler M. 2009. R-type lectins. In Varki A, Cummings R, Esko J, Freeze H, Stanley P, Bertozzi C, Hart G, and Etzler M (eds.), Essentials of Glycobiology. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(2009)
Essentials of Glycobiology
-
-
Cummings, R.1
Etzler, M.2
-
44
-
-
0023091105
-
Structure and evolution of ricin B chain
-
Rutenber E, Ready M, and Robertus JD. 1987. Structure and evolution of ricin B chain. Nature 326:624-626.
-
(1987)
Nature
, vol.326
, pp. 624-626
-
-
Rutenber, E.1
Ready, M.2
Robertus, J.D.3
-
45
-
-
0026605274
-
Phage display of ricin B chain and its single binding domains: System for screening galactose-binding mutants
-
Swimmer C, Lehar SM, McCafferty J, Chiswell DJ, Blattler WA, and Guild BC. 1992. Phage display of ricin B chain and its single binding domains: System for screening galactose-binding mutants. Proc Natl Acad Sci USA 89:3756-3760.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 3756-3760
-
-
Swimmer, C.1
Lehar, S.M.2
McCafferty, J.3
Chiswell, D.J.4
Blattler, W.A.5
Guild, B.C.6
-
46
-
-
0026735969
-
Cell surface and intracellular functions for ricin galactose binding
-
Newton DL, Wales R, Richardson PT, Walbridge S, Saxena SK, Ackerman EJ, Roberts LM, Lord JM, and Youle RJ. 1992. Cell surface and intracellular functions for ricin galactose binding. J Biol Chem 267:11917-11922.
-
(1992)
J Biol Chem
, vol.267
, pp. 11917-11922
-
-
Newton, D.L.1
Wales, R.2
Richardson, P.T.3
Walbridge, S.4
Saxena, S.K.5
Ackerman, E.J.6
Roberts, L.M.7
Lord, J.M.8
Youle, R.J.9
-
47
-
-
0025939115
-
Structure of ricin B-chain at 2.5 Å resolution
-
Rutenber E and Robertus JD. 1991. Structure of ricin B-chain at 2.5 Å resolution. Proteins 10:260-269.
-
(1991)
Proteins
, vol.10
, pp. 260-269
-
-
Rutenber, E.1
Robertus, J.D.2
-
48
-
-
0018078474
-
Binding of galactose and lactose to ricin. Equilibrium studies
-
Zentz C, Frenoy JP, and Bourrillon R. 1978. Binding of galactose and lactose to ricin. Equilibrium studies. Biochim Biophys Acta 536:18-26.
-
(1978)
Biochim Biophys Acta
, vol.536
, pp. 18-26
-
-
Zentz, C.1
Frenoy, J.P.2
Bourrillon, R.3
-
49
-
-
0018787411
-
Structural determinants of Ricinus communis agglutinin and toxin specificity for oligosaccharides
-
Baenziger JU and Fiete D. 1979. Structural determinants of Ricinus communis agglutinin and toxin specificity for oligosaccharides. J Biol Chem 254:9795-9799.
-
(1979)
J Biol Chem
, vol.254
, pp. 9795-9799
-
-
Baenziger, J.U.1
Fiete, D.2
-
50
-
-
0029094651
-
Mutational analysis of the Ricinus lectin B-chains. Galactose-binding ability of the 2 gamma subdomain of Ricinus communis agglutinin B-chain
-
Sphyris N, Lord JM, Wales R, and Roberts LM. 1995. Mutational analysis of the Ricinus lectin B-chains. Galactose-binding ability of the 2 gamma subdomain of Ricinus communis agglutinin B-chain. J Biol Chem 270:20292-20297.
-
(1995)
J Biol Chem
, vol.270
, pp. 20292-20297
-
-
Sphyris, N.1
Lord, J.M.2
Wales, R.3
Roberts, L.M.4
-
51
-
-
33748084389
-
Role of intrachain disulfides in the activities of the CdtA and CdtC subunits of the cytolethal distending toxin of Actinobacillus actinomycetemcomitans
-
Cao L, Volgina A, Korostoff J, and DiRienzo JM. 2006. Role of intrachain disulfides in the activities of the CdtA and CdtC subunits of the cytolethal distending toxin of Actinobacillus actinomycetemcomitans. Infect Immun 74:4990-5002.
-
(2006)
Infect Immun
, vol.74
, pp. 4990-5002
-
-
Cao, L.1
Volgina, A.2
Korostoff, J.3
DiRienzo, J.M.4
-
52
-
-
0347513218
-
Structural analysis by X-ray crystallography and calorimetry of a haemagglutinin component (HA1) of the progenitor toxin from Clostridium botulinum
-
Inoue K, Sobhany M, Transue TR, Oguma K, Pedersen LC, and Negishi M. 2003. Structural analysis by X-ray crystallography and calorimetry of a haemagglutinin component (HA1) of the progenitor toxin from Clostridium botulinum. Microbiology 149:3361-3370.
-
(2003)
Microbiology
, vol.149
, pp. 3361-3370
-
-
Inoue, K.1
Sobhany, M.2
Transue, T.R.3
Oguma, K.4
Pedersen, L.C.5
Negishi, M.6
-
53
-
-
0034967972
-
CdtA, CdtB, and CdtC form a tripartite complex that is required for cytolethal distending toxin activity
-
Lara-Tejero M and Galan JE. 2001. CdtA, CdtB, and CdtC form a tripartite complex that is required for cytolethal distending toxin activity. Infect Immun 69:4358-4365.
-
(2001)
Infect Immun
, vol.69
, pp. 4358-4365
-
-
Lara-Tejero, M.1
Galan, J.E.2
-
54
-
-
2642550772
-
Assembly and function of a bacterial genotoxin
-
Nesic D, Hsu Y, and Stebbins CE. 2004. Assembly and function of a bacterial genotoxin. Nature 429:429-433.
-
(2004)
Nature
, vol.429
, pp. 429-433
-
-
Nesic, D.1
Hsu, Y.2
Stebbins, C.E.3
-
55
-
-
77951036332
-
Mechanisms of assembly and cellular interactions for the bacterial genotoxin CDT
-
Nesic D and Stebbins CE. 2005. Mechanisms of assembly and cellular interactions for the bacterial genotoxin CDT. PLoS Pathog 1:e28.
-
(2005)
PLoS Pathog
, vol.1
, pp. e28
-
-
Nesic, D.1
Stebbins, C.E.2
-
56
-
-
0018185821
-
Homology between ricin and Ricinus communis agglutinin: Amino terminal sequence analysis and protein synthesis inhibition studies
-
Cawley DB, Hedblom ML, and Houston LL. 1978. Homology between ricin and Ricinus communis agglutinin: Amino terminal sequence analysis and protein synthesis inhibition studies. Arch Biochem Biophys 190:744-755.
-
(1978)
Arch Biochem Biophys
, vol.190
, pp. 744-755
-
-
Cawley, D.B.1
Hedblom, M.L.2
Houston, L.L.3
-
57
-
-
0343773778
-
Biochemical studies on ricin. I. Purification of ricin
-
Ishiguro M, Takahashi T, Funatsu G, Hayashi K, and Funatsu M. 1964. Biochemical studies on ricin. I. Purification of ricin. J Biochem 55:587-592.
-
(1964)
J Biochem
, vol.55
, pp. 587-592
-
-
Ishiguro, M.1
Takahashi, T.2
Funatsu, G.3
Hayashi, K.4
Funatsu, M.5
-
58
-
-
0018908163
-
Purification and physicochemical properties of ricins and agglutinins from Ricinus communis
-
Lin TT and Li SL. 1980. Purification and physicochemical properties of ricins and agglutinins from Ricinus communis. Eur J Biochem 105:453-459.
-
(1980)
Eur J Biochem
, vol.105
, pp. 453-459
-
-
Lin, T.T.1
Li, S.L.2
-
59
-
-
0015951279
-
Characterization of two plant lectins from Ricinus communis and their quantitative interaction with a murine lymphoma
-
Nicolson GL, Blaustein J, and Etzler ME. 1974. Characterization of two plant lectins from Ricinus communis and their quantitative interaction with a murine lymphoma. Biochemistry 13:196-204.
-
(1974)
Biochemistry
, vol.13
, pp. 196-204
-
-
Nicolson, G.L.1
Blaustein, J.2
Etzler, M.E.3
-
60
-
-
0022401449
-
The primary sequence of Ricinus communis agglutinin. Comparison with ricin
-
Roberts LM, Lamb FI, Pappin DJ, and Lord JM. 1985. The primary sequence of Ricinus communis agglutinin. Comparison with ricin. J Biol Chem 260:15682-15686.
-
(1985)
J Biol Chem
, vol.260
, pp. 15682-15686
-
-
Roberts, L.M.1
Lamb, F.I.2
Pappin, D.J.3
Lord, J.M.4
-
61
-
-
0023079174
-
The complete amino acid sequence of the B-chain of ricin E isolated from small-grain castor bean seeds. Ricin E is a gene recombination product of ricin D and Ricinus communis agglutinin
-
Araki T and Funatsu G. 1987. The complete amino acid sequence of the B-chain of ricin E isolated from small-grain castor bean seeds. Ricin E is a gene recombination product of ricin D and Ricinus communis agglutinin. Biochim Biophys Acta 911:191-200.
-
(1987)
Biochim Biophys Acta
, vol.911
, pp. 191-200
-
-
Araki, T.1
Funatsu, G.2
-
64
-
-
4043133131
-
Ribosome-inactivating proteins
-
Stirpe F. 2004. Ribosome-inactivating proteins. Toxicon 44:371-383.
-
(2004)
Toxicon
, vol.44
, pp. 371-383
-
-
Stirpe, F.1
-
65
-
-
0016222545
-
Lectins from Abrus precatorius and Ricinus communis. II. Hybrid toxins and their interaction with chain-specific antibodies
-
Olsnes S, Pappenheimer AM, Jr., and Meren R. 1974. Lectins from Abrus precatorius and Ricinus communis. II. Hybrid toxins and their interaction with chain-specific antibodies. J Immunol 113:842-847.
-
(1974)
J Immunol
, vol.113
, pp. 842-847
-
-
Olsnes, S.1
Pappenheimer, A.M.2
Meren, R.3
-
66
-
-
0016168575
-
Lectins from Abrus precatorius and Ricinus communis. I. Immunochemical relationships between toxins and agglutinins
-
Pappenheimer AM, Jr., Olsnes S, and Harper AA. 1974. Lectins from Abrus precatorius and Ricinus communis. I. Immunochemical relationships between toxins and agglutinins. J Immunol 113:835-841.
-
(1974)
J Immunol
, vol.113
, pp. 835-841
-
-
Pappenheimer, A.M.1
Olsnes, S.2
Harper, A.A.3
-
67
-
-
0017074398
-
Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells
-
Sandvig K, Olsnes S, and Pihl A. 1976. Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells. J Biol Chem 251:3977-3984.
-
(1976)
J Biol Chem
, vol.251
, pp. 3977-3984
-
-
Sandvig, K.1
Olsnes, S.2
Pihl, A.3
-
68
-
-
0018760797
-
Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells
-
Sandvig K and Olsnes S. 1979. Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells. Exp Cell Res 121:15-25.
-
(1979)
Exp Cell Res
, vol.121
, pp. 15-25
-
-
Sandvig, K.1
Olsnes, S.2
-
69
-
-
0020265159
-
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles
-
Sandvig K and Olsnes S. 1982. Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles. J Biol Chem 257:7504-7513.
-
(1982)
J Biol Chem
, vol.257
, pp. 7504-7513
-
-
Sandvig, K.1
Olsnes, S.2
-
70
-
-
0020287244
-
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium
-
Sandvig K and Olsnes S. 1982. Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium. J Biol Chem 257:7495-7503.
-
(1982)
J Biol Chem
, vol.257
, pp. 7495-7503
-
-
Sandvig, K.1
Olsnes, S.2
-
71
-
-
0022005540
-
Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin but not that of ricin toxin
-
Moya M, Dautry-Varsat A, Goud B, Louvard D, and Boquet P. 1985. Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin but not that of ricin toxin. J Cell Biol 101:548-559.
-
(1985)
J Cell Biol
, vol.101
, pp. 548-559
-
-
Moya, M.1
Dautry-Varsat, A.2
Goud, B.3
Louvard, D.4
Boquet, P.5
-
72
-
-
0023582912
-
Acidification of the cytosol inhibits endocytosis from coated pits
-
Sandvig K, Olsnes S, Petersen OW, and van Deurs B. 1987. Acidification of the cytosol inhibits endocytosis from coated pits. J Cell Biol 105:679-689.
-
(1987)
J Cell Biol
, vol.105
, pp. 679-689
-
-
Sandvig, K.1
Olsnes, S.2
Petersen, O.W.3
van Deurs, B.4
-
73
-
-
0030929658
-
Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol
-
Rapak A, Falnes PO, and Olsnes S. 1997. Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol. Proc Natl Acad Sci USA 94:3783-3788.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3783-3788
-
-
Rapak, A.1
Falnes, P.O.2
Olsnes, S.3
-
74
-
-
0022619529
-
Routing of internalized ricin and ricin conjugates to the Golgi complex
-
van Deurs B, Tonnessen TI, Petersen OW, Sandvig K, and Olsnes S. 1986. Routing of internalized ricin and ricin conjugates to the Golgi complex. J Cell Biol 102:37-47.
-
(1986)
J Cell Biol
, vol.102
, pp. 37-47
-
-
van Deurs, B.1
Tonnessen, T.I.2
Petersen, O.W.3
Sandvig, K.4
Olsnes, S.5
-
75
-
-
0023878452
-
Estimation of the amount of internalized ricin that reaches the trans-Golgi network
-
van Deurs B, Sandvig K, Petersen OW, Olsnes S, Simons K, and Griffiths G. 1988. Estimation of the amount of internalized ricin that reaches the trans-Golgi network. J Cell Biol 106:253-267.
-
(1988)
J Cell Biol
, vol.106
, pp. 253-267
-
-
van Deurs, B.1
Sandvig, K.2
Petersen, O.W.3
Olsnes, S.4
Simons, K.5
Griffiths, G.6
-
76
-
-
79956042755
-
A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation
-
Sokolowska I, Walchli S, Wegrzyn G, Sandvig K, and Slominska-Wojewodzka M. 2011. A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation. Biochem J 436:371-385.
-
(2011)
Biochem J
, vol.436
, pp. 371-385
-
-
Sokolowska, I.1
Walchli, S.2
Wegrzyn, G.3
Sandvig, K.4
Slominska-Wojewodzka, M.5
-
77
-
-
7444241345
-
Protein disulphide-isomerase reduces ricin to its A and B chains in the endoplasmic reticulum
-
Spooner RA, Watson PD, Marsden CJ, Smith DC, Moore KA, Cook JP, Lord JM, and Roberts LM. 2004. Protein disulphide-isomerase reduces ricin to its A and B chains in the endoplasmic reticulum. Biochem J 383:285-293.
-
(2004)
Biochem J
, vol.383
, pp. 285-293
-
-
Spooner, R.A.1
Watson, P.D.2
Marsden, C.J.3
Smith, D.C.4
Moore, K.A.5
Cook, J.P.6
Lord, J.M.7
Roberts, L.M.8
-
78
-
-
0030044963
-
Major structural differences between pokeweed antiviral protein and ricin A-chain do not account for their differing ribosome specificity
-
Chaddock JA, Monzingo AF, Robertus JD, Lord JM, and Roberts LM. 1996. Major structural differences between pokeweed antiviral protein and ricin A-chain do not account for their differing ribosome specificity. Eur J Biochem 235:159-166.
-
(1996)
Eur J Biochem
, vol.235
, pp. 159-166
-
-
Chaddock, J.A.1
Monzingo, A.F.2
Robertus, J.D.3
Lord, J.M.4
Roberts, L.M.5
-
79
-
-
0037176821
-
Binding of ricin A-chain to negatively charged phospholipid vesicles leads to protein structural changes and destabilizes the lipid bilayer
-
Day PJ, Pinheiro TJ, Roberts LM, and Lord JM. 2002. Binding of ricin A-chain to negatively charged phospholipid vesicles leads to protein structural changes and destabilizes the lipid bilayer. Biochemistry 41:2836-2843.
-
(2002)
Biochemistry
, vol.41
, pp. 2836-2843
-
-
Day, P.J.1
Pinheiro, T.J.2
Roberts, L.M.3
Lord, J.M.4
-
80
-
-
65649138069
-
Ricin A chain insertion into endoplasmic reticulum membranes is triggered by a temperature increase to 37°C
-
Mayerhofer PU, Cook JP, Wahlman J, Pinheiro TT, Moore KA, Lord JM, Johnson AE, and Roberts LM. 2009. Ricin A chain insertion into endoplasmic reticulum membranes is triggered by a temperature increase to 37°C. J Biol Chem 284:10232-10242.
-
(2009)
J Biol Chem
, vol.284
, pp. 10232-10242
-
-
Mayerhofer, P.U.1
Cook, J.P.2
Wahlman, J.3
Pinheiro, T.T.4
Moore, K.A.5
Lord, J.M.6
Johnson, A.E.7
Roberts, L.M.8
-
81
-
-
4143103548
-
Finding a new vaccine in the ricin protein fold
-
Olson MA, Carra JH, Roxas-Duncan V, Wannemacher RW, Smith LA, and Millard CB. 2004. Finding a new vaccine in the ricin protein fold. Protein Eng Des Sel 17:391-397.
-
(2004)
Protein Eng Des Sel
, vol.17
, pp. 391-397
-
-
Olson, M.A.1
Carra, J.H.2
Roxas-Duncan, V.3
Wannemacher, R.W.4
Smith, L.A.5
Millard, C.B.6
-
82
-
-
0034737432
-
Ribosome-mediated folding of partially unfolded ricin A-chain
-
Argent RH, Parrott AM, Day PJ, Roberts LM, Stockley PG, Lord JM, and Radford SE. 2000. Ribosome-mediated folding of partially unfolded ricin A-chain. J Biol Chem 275:9263-9269.
-
(2000)
J Biol Chem
, vol.275
, pp. 9263-9269
-
-
Argent, R.H.1
Parrott, A.M.2
Day, P.J.3
Roberts, L.M.4
Stockley, P.G.5
Lord, J.M.6
Radford, S.E.7
-
83
-
-
77955106651
-
Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulum
-
Li S, Spooner RA, Allen SC, Guise CP, Ladds G, Schnoder T, Schmitt MJ, Lord JM, and Roberts LM. 2010. Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulum. Mol Biol Cell 21:2543-2554.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 2543-2554
-
-
Li, S.1
Spooner, R.A.2
Allen, S.C.3
Guise, C.P.4
Ladds, G.5
Schnoder, T.6
Schmitt, M.J.7
Lord, J.M.8
Roberts, L.M.9
-
84
-
-
56249144175
-
Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum
-
Spooner RA, Hart PJ, Cook JP, Pietroni P, Rogon C, Hohfeld J, Roberts LM, and Lord JM. 2008. Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum. Proc Natl Acad Sci USA 105:17408-17413.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 17408-17413
-
-
Spooner, R.A.1
Hart, P.J.2
Cook, J.P.3
Pietroni, P.4
Rogon, C.5
Hohfeld, J.6
Roberts, L.M.7
Lord, J.M.8
-
85
-
-
84867229684
-
N-Glycosylation does not affect the catalytic activity of ricin a chain but stimulates cytotoxicity by promoting its transport out of the endoplasmic reticulum
-
Yan Q, Li XP, and Tumer NE. 2012. N-Glycosylation does not affect the catalytic activity of ricin a chain but stimulates cytotoxicity by promoting its transport out of the endoplasmic reticulum. Traffic 13:1508-1521.
-
(2012)
Traffic
, vol.13
, pp. 1508-1521
-
-
Yan, Q.1
Li, X.P.2
Tumer, N.E.3
-
86
-
-
0023947126
-
The RNA N-glycosidase activity of ricin A-chain. The characteristics of the enzymatic activity of ricin A-chain with ribosomes and with rRNA
-
Endo Y and Tsurugi K. 1988. The RNA N-glycosidase activity of ricin A-chain. The characteristics of the enzymatic activity of ricin A-chain with ribosomes and with rRNA. J Biol Chem 263:8735-8739.
-
(1988)
J Biol Chem
, vol.263
, pp. 8735-8739
-
-
Endo, Y.1
Tsurugi, K.2
-
87
-
-
84867103425
-
The P1/P2 proteins of the human ribosomal stalk are required for ribosome binding and depurination by ricin in human cells
-
May KL, Li XP, Martinez-Azorin F, Ballesta JP, Grela P, Tchorzewski M, and Tumer NE. 2012. The P1/P2 proteins of the human ribosomal stalk are required for ribosome binding and depurination by ricin in human cells. FEBS J 279(20):3925-3936.
-
(2012)
FEBS J
, vol.279
, Issue.20
, pp. 3925-3936
-
-
May, K.L.1
Li, X.P.2
Martinez-Azorin, F.3
Ballesta, J.P.4
Grela, P.5
Tchorzewski, M.6
Tumer, N.E.7
-
88
-
-
0028318143
-
The ribosomal RNA identity elements for ricin and for alpha-sarcin: Mutations in the putative CG pair that closes a GAGA tetraloop
-
Gluck A, Endo Y, and Wool IG. 1994. The ribosomal RNA identity elements for ricin and for alpha-sarcin: Mutations in the putative CG pair that closes a GAGA tetraloop. Nucleic Acids Res 22:321-324.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 321-324
-
-
Gluck, A.1
Endo, Y.2
Wool, I.G.3
-
89
-
-
0023722010
-
Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA
-
Moazed D, Robertson JM, and Noller HF. 1988. Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA. Nature 334:362-364.
-
(1988)
Nature
, vol.334
, pp. 362-364
-
-
Moazed, D.1
Robertson, J.M.2
Noller, H.F.3
-
90
-
-
84860767838
-
Functional role of the sarcin-ricin loop of the 23S rRNA in the elongation cycle of protein synthesis
-
Shi X, Khade PK, Sanbonmatsu KY, and Joseph S. 2012. Functional role of the sarcin-ricin loop of the 23S rRNA in the elongation cycle of protein synthesis. J Mol Biol 419:125-138.
-
(2012)
J Mol Biol
, vol.419
, pp. 125-138
-
-
Shi, X.1
Khade, P.K.2
Sanbonmatsu, K.Y.3
Joseph, S.4
-
91
-
-
0026469648
-
X-ray analysis of substrate analogs in the ricin A-chain active site
-
Monzingo AF and Robertus JD. 1992. X-ray analysis of substrate analogs in the ricin A-chain active site. J Mol Biol 227:1136-1145.
-
(1992)
J Mol Biol
, vol.227
, pp. 1136-1145
-
-
Monzingo, A.F.1
Robertus, J.D.2
-
92
-
-
0028099436
-
X-ray structure of recombinant ricin A-chain at 1.8 Å resolution
-
Weston SA, Tucker AD, Thatcher DR, Derbyshire DJ, and Pauptit RA. 1994. X-ray structure of recombinant ricin A-chain at 1.8 Å resolution. J Mol Biol 244:410-422.
-
(1994)
J Mol Biol
, vol.244
, pp. 410-422
-
-
Weston, S.A.1
Tucker, A.D.2
Thatcher, D.R.3
Derbyshire, D.J.4
Pauptit, R.A.5
-
93
-
-
0031277394
-
Molecular docking of superantigens with class II major histocompatibility complex proteins
-
Olson MA and Cuff L. 1997. Molecular docking of superantigens with class II major histocompatibility complex proteins. J Mol Recognit 10:277-289.
-
(1997)
J Mol Recognit
, vol.10
, pp. 277-289
-
-
Olson, M.A.1
Cuff, L.2
-
94
-
-
0025986909
-
Site-directed mutagenesis of ricin A-chain and implications for the mechanism of action
-
Ready MP, Kim Y, and Robertus JD. 1991. Site-directed mutagenesis of ricin A-chain and implications for the mechanism of action. Proteins 10:270-278.
-
(1991)
Proteins
, vol.10
, pp. 270-278
-
-
Ready, M.P.1
Kim, Y.2
Robertus, J.D.3
-
95
-
-
0031567126
-
Structure-based identification of a ricin inhibitor
-
Yan X, Hollis T, Svinth M, Day P, Monzingo AF, Milne GW, and Robertus JD. 1997. Structure-based identification of a ricin inhibitor. J Mol Biol 266:1043-1049.
-
(1997)
J Mol Biol
, vol.266
, pp. 1043-1049
-
-
Yan, X.1
Hollis, T.2
Svinth, M.3
Day, P.4
Monzingo, A.F.5
Milne, G.W.6
Robertus, J.D.7
-
96
-
-
0026740874
-
Structure of a ricin mutant showing rescue of activity by a noncatalytic residue
-
Kim Y, Mlsna D, Monzingo AF, Ready MP, Frankel A, and Robertus JD. 1992. Structure of a ricin mutant showing rescue of activity by a noncatalytic residue. Biochemistry 31:3294-3296.
-
(1992)
Biochemistry
, vol.31
, pp. 3294-3296
-
-
Kim, Y.1
Mlsna, D.2
Monzingo, A.F.3
Ready, M.P.4
Frankel, A.5
Robertus, J.D.6
-
97
-
-
0027050799
-
Analysis of several key active site residues of ricin A chain by mutagenesis and X-ray crystallography
-
Kim Y and Robertus JD. 1992. Analysis of several key active site residues of ricin A chain by mutagenesis and X-ray crystallography. Protein Eng 5:775-779.
-
(1992)
Protein Eng
, vol.5
, pp. 775-779
-
-
Kim, Y.1
Robertus, J.D.2
-
98
-
-
0025291257
-
Site-directed mutagenesis of ricin A chain Trp 211 to Phe
-
Bradley JL and McGuire PM. 1990. Site-directed mutagenesis of ricin A chain Trp 211 to Phe. Int J Pept Protein Res 35:365-366.
-
(1990)
Int J Pept Protein Res
, vol.35
, pp. 365-366
-
-
Bradley, J.L.1
McGuire, P.M.2
-
99
-
-
0030973162
-
Ribotoxic stress response: Activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA
-
Iordanov MS, Pribnow D, Magun JL, Dinh TH, Pearson JA, Chen SL, and Magun BE. 1997. Ribotoxic stress response: Activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA. Mol Cell Biol 17:3373-3381.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3373-3381
-
-
Iordanov, M.S.1
Pribnow, D.2
Magun, J.L.3
Dinh, T.H.4
Pearson, J.A.5
Chen, S.L.6
Magun, B.E.7
-
101
-
-
45249123044
-
ZAK: A MAP3 kinase that transduces shiga toxin- and ricin-induced proinflammatory cytokine expression
-
Jandhyala DM, Ahluwalia A, Obrig T, and Thorpe CM. 2008. ZAK: A MAP3 kinase that transduces shiga toxin- and ricin-induced proinflammatory cytokine expression. Cell Microbiol 10:1468-1477.
-
(2008)
Cell Microbiol
, vol.10
, pp. 1468-1477
-
-
Jandhyala, D.M.1
Ahluwalia, A.2
Obrig, T.3
Thorpe, C.M.4
-
102
-
-
1342346733
-
Cross-talk between the pathways leading to the induction of apoptosis and the secretion of tumor necrosis factor-alpha in ricin-treated RAW 264.7 cells
-
Higuchi S, Tamura T, and Oda T. 2003. Cross-talk between the pathways leading to the induction of apoptosis and the secretion of tumor necrosis factor-alpha in ricin-treated RAW 264.7 cells. J Biochem (Tokyo) 134:927-933.
-
(2003)
J Biochem (Tokyo)
, vol.134
, pp. 927-933
-
-
Higuchi, S.1
Tamura, T.2
Oda, T.3
-
103
-
-
0037373313
-
Shiga toxin 1 triggers a ribotoxic stress response leading to p38 and JNK activation and induction of apoptosis in intestinal epithelial cells
-
Smith WE, Kane AV, Campbell ST, Acheson DW, Cochran BH, and Thorpe CM. 2003. Shiga toxin 1 triggers a ribotoxic stress response leading to p38 and JNK activation and induction of apoptosis in intestinal epithelial cells. Infect Immun 71:1497-1504.
-
(2003)
Infect Immun
, vol.71
, pp. 1497-1504
-
-
Smith, W.E.1
Kane, A.V.2
Campbell, S.T.3
Acheson, D.W.4
Cochran, B.H.5
Thorpe, C.M.6
-
104
-
-
77955497819
-
ZAK is required for doxorubicin, a novel ribotoxic stressor, to induce SAPK activation and apoptosis in HaCaT cells
-
Sauter KA, Magun EA, Iordanov MS, and Magun BE. 2010. ZAK is required for doxorubicin, a novel ribotoxic stressor, to induce SAPK activation and apoptosis in HaCaT cells. Cancer Biol Ther 10:258-266.
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 258-266
-
-
Sauter, K.A.1
Magun, E.A.2
Iordanov, M.S.3
Magun, B.E.4
-
105
-
-
12744279203
-
The mannose receptor: Linking homeostasis and immunity through sugar recognition
-
Taylor PR, Gordon S, and Martinez-Pomares L. 2005. The mannose receptor: Linking homeostasis and immunity through sugar recognition. Trends Immunol 26:104-110.
-
(2005)
Trends Immunol
, vol.26
, pp. 104-110
-
-
Taylor, P.R.1
Gordon, S.2
Martinez-Pomares, L.3
-
106
-
-
0027174451
-
Endocytosis of ricin by rat liver cells in vivo and in vitro is mainly mediated by mannose receptors on sinusoidal endothelial cells
-
Magnusson S and Berg T. 1993. Endocytosis of ricin by rat liver cells in vivo and in vitro is mainly mediated by mannose receptors on sinusoidal endothelial cells. Biochem J 291(Pt 3):749-755.
-
(1993)
Biochem J
, vol.291
, pp. 749-755
-
-
Magnusson, S.1
Berg, T.2
-
107
-
-
0025887805
-
Interactions of ricin with sinusoidal endothelial rat liver cells. Different involvement of two distinct carbohydrate-specific mechanisms in surface binding and internalization
-
Magnusson S, Berg T, Turpin E, and Frenoy JP. 1991. Interactions of ricin with sinusoidal endothelial rat liver cells. Different involvement of two distinct carbohydrate-specific mechanisms in surface binding and internalization. Biochem J 277(Pt 3):855-861.
-
(1991)
Biochem J
, vol.277
, pp. 855-861
-
-
Magnusson, S.1
Berg, T.2
Turpin, E.3
Frenoy, J.P.4
-
108
-
-
0027160323
-
Characterization of two distinct pathways of endocytosis of ricin by rat liver endothelial cells
-
Magnusson S, Kjeken R, and Berg T. 1993. Characterization of two distinct pathways of endocytosis of ricin by rat liver endothelial cells. Exp Cell Res 205:118-125.
-
(1993)
Exp Cell Res
, vol.205
, pp. 118-125
-
-
Magnusson, S.1
Kjeken, R.2
Berg, T.3
-
109
-
-
80053189045
-
Role of the mannose receptor (CD206) in immunity to ricin
-
Gage E, Hernandez MO, O’Hara JM, McCarthy EA, and Mantis NJ. 2011. Role of the mannose receptor (CD206) in immunity to ricin. Toxins (Basel) 3(9):1131-1145.
-
(2011)
Toxins (Basel)
, vol.3
, Issue.9
, pp. 1131-1145
-
-
Gage, E.1
Hernandez, M.O.2
O’Hara, J.M.3
McCarthy, E.A.4
Mantis, N.J.5
-
110
-
-
27744564219
-
Ricin poisoning: A comprehensive review
-
Audi J, Belson M, Patel M, Schier J, and Osterloh J. 2005. Ricin poisoning: A comprehensive review. JAMA 294:2342-2351.
-
(2005)
JAMA
, vol.294
, pp. 2342-2351
-
-
Audi, J.1
Belson, M.2
Patel, M.3
Schier, J.4
Osterloh, J.5
-
111
-
-
0142088893
-
Ricin poisoning
-
Bradberry SM, Dickers KJ, Rice P, Griffiths GD, and Vale JA. 2003. Ricin poisoning. Toxicol Rev 22:65-70.
-
(2003)
Toxicol Rev
, vol.22
, pp. 65-70
-
-
Bradberry, S.M.1
Dickers, K.J.2
Rice, P.3
Griffiths, G.D.4
Vale, J.A.5
-
112
-
-
80053215154
-
Passive and active vaccination strategies to prevent ricin poisoning
-
Pincus SH, Smallshaw JE, Song K, Berry J, and Vitetta ES. 2011. Passive and active vaccination strategies to prevent ricin poisoning. Toxins (Basel) 3:1163-1184.
-
(2011)
Toxins (Basel)
, vol.3
, pp. 1163-1184
-
-
Pincus, S.H.1
Smallshaw, J.E.2
Song, K.3
Berry, J.4
Vitetta, E.S.5
-
113
-
-
0030886158
-
Ultrastructure of rat lung following inhalation of ricin aerosol
-
Brown RF and White DE. 1997. Ultrastructure of rat lung following inhalation of ricin aerosol. Int J Exp Path 78:267-276.
-
(1997)
Int J Exp Path
, vol.78
, pp. 267-276
-
-
Brown, R.F.1
White, D.E.2
-
114
-
-
0038696357
-
Pulmonary gene expression profiling of inhaled ricin
-
DaSilva L, Cote D, Roy C, Martinez M, Duniho S, Pitt ML, Downey T, and Dertzbaugh M. 2003. Pulmonary gene expression profiling of inhaled ricin. Toxicon 41:813-822.
-
(2003)
Toxicon
, vol.41
, pp. 813-822
-
-
DaSilva, L.1
Cote, D.2
Roy, C.3
Martinez, M.4
Duniho, S.5
Pitt, M.L.6
Downey, T.7
Dertzbaugh, M.8
-
115
-
-
0028987718
-
The distribution of [125I]ricin in mice following aerosol inhalation exposure
-
Doebler JA, Wiltshire ND, Mayer TW, Estep JE, Moeller RB, Traub RK, Broomfield CA, Calamaio CA, Thompson WL, and Pitt ML. 1995. The distribution of [125I]ricin in mice following aerosol inhalation exposure. Toxicology 98:137-149.
-
(1995)
Toxicology
, vol.98
, pp. 137-149
-
-
Doebler, J.A.1
Wiltshire, N.D.2
Mayer, T.W.3
Estep, J.E.4
Moeller, R.B.5
Traub, R.K.6
Broomfield, C.A.7
Calamaio, C.A.8
Thompson, W.L.9
Pitt, M.L.10
-
116
-
-
0033523046
-
Comparison of the quality of protection elicited by toxoid and peptide liposomal vaccine formulations against ricin as assessed by markers of inflammation
-
Griffiths GD, Phillips GJ, and Bailey SC. 1999. Comparison of the quality of protection elicited by toxoid and peptide liposomal vaccine formulations against ricin as assessed by markers of inflammation. Vaccine 17:2562-2568.
-
(1999)
Vaccine
, vol.17
, pp. 2562-2568
-
-
Griffiths, G.D.1
Phillips, G.J.2
Bailey, S.C.3
-
117
-
-
84863393032
-
Protective effect of two recombinant ricin subunit vaccines in the New Zealand white rabbit subjected to a lethal aerosolized ricin challenge: Survival, immunological response and histopathological findings
-
McLain DE, Lewis BS, Chapman JL, Wannemacher RW, Lindsey CY, and Smith LA. 2011. Protective effect of two recombinant ricin subunit vaccines in the New Zealand white rabbit subjected to a lethal aerosolized ricin challenge: Survival, immunological response and histopathological findings. Toxicol Sci 126(1):72-83.
-
(2011)
Toxicol Sci
, vol.126
, Issue.1
, pp. 72-83
-
-
McLain, D.E.1
Lewis, B.S.2
Chapman, J.L.3
Wannemacher, R.W.4
Lindsey, C.Y.5
Smith, L.A.6
-
118
-
-
0030147202
-
Lesions of acute inhaled lethal ricin intoxication in rhesus monkeys
-
Wilhelmsen CL and Pitt ML. 1996. Lesions of acute inhaled lethal ricin intoxication in rhesus monkeys. Vet Pathol 33:296-302.
-
(1996)
Vet Pathol
, vol.33
, pp. 296-302
-
-
Wilhelmsen, C.L.1
Pitt, M.L.2
-
119
-
-
34748918488
-
RiVax, a recombinant ricin subunit vaccine, protects mice against ricin delivered by gavage or aerosol
-
Smallshaw JE, Richardson JA, and Vitetta ES. 2007. RiVax, a recombinant ricin subunit vaccine, protects mice against ricin delivered by gavage or aerosol. Vaccine 25:7459-7469.
-
(2007)
Vaccine
, vol.25
, pp. 7459-7469
-
-
Smallshaw, J.E.1
Richardson, J.A.2
Vitetta, E.S.3
-
120
-
-
34147161710
-
Evidence for widespread epithelial damage and coincident production of monocyte chemotactic protein 1 in a murine model of intestinal ricin intoxication
-
Yoder JM, Aslam RU, and Mantis NJ. 2007. Evidence for widespread epithelial damage and coincident production of monocyte chemotactic protein 1 in a murine model of intestinal ricin intoxication. Infect Immun 75:1745-1750.
-
(2007)
Infect Immun
, vol.75
, pp. 1745-1750
-
-
Yoder, J.M.1
Aslam, R.U.2
Mantis, N.J.3
-
121
-
-
1942466007
-
The histological changes produced by ricin and abrin intoxications
-
Flexner S. 1897. The histological changes produced by ricin and abrin intoxications. J Exp Med 2:197-220.
-
(1897)
J Exp Med
, vol.2
, pp. 197-220
-
-
Flexner, S.1
-
122
-
-
0021177979
-
Effects of ricin, a protein toxin, on glucose absorption by rat small intestine. (Biochemical studies on oral toxicity of ricin. II.)
-
Ishiguro M, Harada H, Ichiki O, Sekine I, Nishimori I, and Kikutani M. 1984. Effects of ricin, a protein toxin, on glucose absorption by rat small intestine. (Biochemical studies on oral toxicity of ricin. II.) Chem Pharm Bull 32:3141-3147.
-
(1984)
Chem Pharm Bull
, vol.32
, pp. 3141-3147
-
-
Ishiguro, M.1
Harada, H.2
Ichiki, O.3
Sekine, I.4
Nishimori, I.5
Kikutani, M.6
-
123
-
-
0026588998
-
Interaction of toxic lectin ricin with epithelial cells of rat small intestine in vitro
-
Ishiguro M, Nakashima H, Tanabe S, and Sakakibara R. 1992. Interaction of toxic lectin ricin with epithelial cells of rat small intestine in vitro. Chem Pharm Bull 40:441-445.
-
(1992)
Chem Pharm Bull
, vol.40
, pp. 441-445
-
-
Ishiguro, M.1
Nakashima, H.2
Tanabe, S.3
Sakakibara, R.4
-
124
-
-
0026656484
-
Biochemical studies on oral toxicity of ricin. IV. A fate of orally administered ricin in rats
-
Ishiguro M, Tanabe S, Matori Y, and Sakakibara R. 1992. Biochemical studies on oral toxicity of ricin. IV. A fate of orally administered ricin in rats. J Pharmacobiodyn 15:147-156.
-
(1992)
J Pharmacobiodyn
, vol.15
, pp. 147-156
-
-
Ishiguro, M.1
Tanabe, S.2
Matori, Y.3
Sakakibara, R.4
-
125
-
-
0022971461
-
Pathological study on mucosal changes in small intestine of rat by oral administration of ricin. I. Microscopical observation
-
Sekine I, Kawase Y, Nishimori I, Mitarai M, Harada H, Ishiguro M, and Kikutani M. 1986. Pathological study on mucosal changes in small intestine of rat by oral administration of ricin. I. Microscopical observation. Acta Pathol Jpn 36:1205-1212.
-
(1986)
Acta Pathol Jpn
, vol.36
, pp. 1205-1212
-
-
Sekine, I.1
Kawase, Y.2
Nishimori, I.3
Mitarai, M.4
Harada, H.5
Ishiguro, M.6
Kikutani, M.7
-
126
-
-
0026631759
-
Biochemical studies on oral toxicity of ricin. V. The role of lectin activity in the intestinal absorption of ricin
-
Ishiguro M, Matori Y, Tanabe S, Kawase Y, Sekine I, and Sakakibara R. 1992. Biochemical studies on oral toxicity of ricin. V. The role of lectin activity in the intestinal absorption of ricin. Chem Pharm Bull 40:1216-1220.
-
(1992)
Chem Pharm Bull
, vol.40
, pp. 1216-1220
-
-
Ishiguro, M.1
Matori, Y.2
Tanabe, S.3
Kawase, Y.4
Sekine, I.5
Sakakibara, R.6
-
127
-
-
33646905629
-
Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxication
-
Mantis NJ, McGuinness CR, Sonuyi O, Edwards G, and Farrant SA. 2006. Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxication. Infect Immun 74:3455-3462.
-
(2006)
Infect Immun
, vol.74
, pp. 3455-3462
-
-
Mantis, N.J.1
McGuinness, C.R.2
Sonuyi, O.3
Edwards, G.4
Farrant, S.A.5
-
128
-
-
0025125795
-
Endocytosis, intracellular transport and transcytosis of the toxic protein ricin by a polarized epithelium
-
van Deurs B, Hansen SH, Petersen OW, Melby EL, and Sandvig K. 1990. Endocytosis, intracellular transport and transcytosis of the toxic protein ricin by a polarized epithelium. Eur J Cell Biol 51:96-109.
-
(1990)
Eur J Cell Biol
, vol.51
, pp. 96-109
-
-
van Deurs, B.1
Hansen, S.H.2
Petersen, O.W.3
Melby, E.L.4
Sandvig, K.5
-
129
-
-
0032707715
-
Shiga toxins stimulate secretion of interleukin-8 from intestinal epithelial cells
-
Thorpe CM, Hurley BP, Lincicome LL, Jacewicz MS, Keusch GT, and Acheson DW. 1999. Shiga toxins stimulate secretion of interleukin-8 from intestinal epithelial cells. Infect Immun 67:5985-5993.
-
(1999)
Infect Immun
, vol.67
, pp. 5985-5993
-
-
Thorpe, C.M.1
Hurley, B.P.2
Lincicome, L.L.3
Jacewicz, M.S.4
Keusch, G.T.5
Acheson, D.W.6
-
130
-
-
0034819669
-
Shiga toxins induce, superinduce, and stabilize a variety of C-X-C chemokine mRNAs in intestinal epithelial cells, resulting in increased chemokine expression
-
Thorpe CM, Smith WE, Hurley BP, and Acheson DW. 2001. Shiga toxins induce, superinduce, and stabilize a variety of C-X-C chemokine mRNAs in intestinal epithelial cells, resulting in increased chemokine expression. Infect Immun 69:6140-6147.
-
(2001)
Infect Immun
, vol.69
, pp. 6140-6147
-
-
Thorpe, C.M.1
Smith, W.E.2
Hurley, B.P.3
Acheson, D.W.4
-
131
-
-
1542358177
-
Induction of cytokines by toxins that have an identical RNA N-glycosidase activity: Shiga toxin, ricin, and modeccin
-
Yamasaki C, Nishikawa K, Zeng XT, Katayama Y, Natori Y, Komatsu N, and Oda T. 2004. Induction of cytokines by toxins that have an identical RNA N-glycosidase activity: Shiga toxin, ricin, and modeccin. Biochim Biophys Acta 1671:44-50.
-
(2004)
Biochim Biophys Acta
, vol.1671
, pp. 44-50
-
-
Yamasaki, C.1
Nishikawa, K.2
Zeng, X.T.3
Katayama, Y.4
Natori, Y.5
Komatsu, N.6
Oda, T.7
-
132
-
-
84872519838
-
Single domain antibodies for the detection of ricin using silicon photonic microring resonator arrays
-
Shia WW and Bailey RC. 2012. Single domain antibodies for the detection of ricin using silicon photonic microring resonator arrays. Anal Chem 85(2):805-810.
-
(2012)
Anal Chem
, vol.85
, Issue.2
, pp. 805-810
-
-
Shia, W.W.1
Bailey, R.C.2
-
133
-
-
84867046196
-
Simultaneous detection of ricin and abrin DNA by real-time PCR (qPCR)
-
Felder E, Mossbrugger I, Lange M, and Wolfel R. 2012. Simultaneous detection of ricin and abrin DNA by real-time PCR (qPCR). Toxins (Basel) 4:633-642.
-
(2012)
Toxins (Basel)
, vol.4
, pp. 633-642
-
-
Felder, E.1
Mossbrugger, I.2
Lange, M.3
Wolfel, R.4
-
134
-
-
77958474676
-
Ricin toxicokinetics and its sensitive detection in mouse sera or feces using immuno-PCR
-
He X, McMahon S, Henderson TD, 2nd, Griffey SM, and Cheng LW. 2010. Ricin toxicokinetics and its sensitive detection in mouse sera or feces using immuno-PCR. PLoS One 5:e12858.
-
(2010)
PLoS One
, vol.5
-
-
He, X.1
McMahon, S.2
Henderson, T.D.3
Griffey, S.M.4
Cheng, L.W.5
-
135
-
-
79957598901
-
Analysis of active ricin and castor bean proteins in a ricin preparation, castor bean extract, and surface swabs from a public health investigation
-
Schieltz DM, McGrath SC, McWilliams LG, Rees J, Bowen MD, Kools JJ, Dauphin LA et al. 2011. Analysis of active ricin and castor bean proteins in a ricin preparation, castor bean extract, and surface swabs from a public health investigation. Forensic Sci Int 209(1-3):70-79.
-
(2011)
Forensic Sci Int
, vol.209
, Issue.1-3
, pp. 70-79
-
-
Schieltz, D.M.1
McGrath, S.C.2
McWilliams, L.G.3
Rees, J.4
Bowen, M.D.5
Kools, J.J.6
Dauphin, L.A.7
-
136
-
-
0036570711
-
Rapid and sensitive detection of biological warfare agents using time-resolved fluorescence assays
-
Peruski AH, Johnson LH, 3rd, and Peruski LF, Jr. 2002. Rapid and sensitive detection of biological warfare agents using time-resolved fluorescence assays. J Immunol Methods 263:35-41.
-
(2002)
J Immunol Methods
, vol.263
, pp. 35-41
-
-
Peruski, A.H.1
Johnson, L.H.2
Peruski, L.F.3
-
137
-
-
84864938678
-
Bayesian integration of isotope ratio for geographic sourcing of castor beans
-
Webb-Robertson BJ, Kreuzer H, Hart G, Ehleringer J, West J, Gill G, and Duckworth D. 2012. Bayesian integration of isotope ratio for geographic sourcing of castor beans. J Biomed Biotechnol 2012:450967.
-
(2012)
J Biomed Biotechnol
, vol.2012
, pp. 450967
-
-
Webb-Robertson, B.J.1
Kreuzer, H.2
Hart, G.3
Ehleringer, J.4
West, J.5
Gill, G.6
Duckworth, D.7
-
138
-
-
78650458476
-
Development of a quantitative RT-PCR assay to examine the kinetics of ribosome depurination by ribosome inactivating proteins using Saccharomyces cerevisiae as a model
-
Pierce M, Kahn JN, Chiou J, and Tumer NE. 2011. Development of a quantitative RT-PCR assay to examine the kinetics of ribosome depurination by ribosome inactivating proteins using Saccharomyces cerevisiae as a model. RNA 17:201-210.
-
(2011)
RNA
, vol.17
, pp. 201-210
-
-
Pierce, M.1
Kahn, J.N.2
Chiou, J.3
Tumer, N.E.4
-
139
-
-
0025145485
-
Direct injection of blood samples into a high-performance liquid chromatographic adenine analyser to measure adenine, adenosine, and the adenine nucleotides with fluorescence detection
-
Fujimori H, Sasaki T, Hibi K, Senda M, and Yoshioka M. 1990. Direct injection of blood samples into a high-performance liquid chromatographic adenine analyser to measure adenine, adenosine, and the adenine nucleotides with fluorescence detection. J Chromatogr 515:363-373.
-
(1990)
J Chromatogr
, vol.515
, pp. 363-373
-
-
Fujimori, H.1
Sasaki, T.2
Hibi, K.3
Senda, M.4
Yoshioka, M.5
-
140
-
-
0024597110
-
High-pressure-liquid-chromatographic and fluorimetric methods for the determination of adenine released from ribosomes by ricin and gelonin
-
Zamboni M, Brigotti M, Rambelli F, Montanaro L, and Sperti S. 1989. High-pressure-liquid-chromatographic and fluorimetric methods for the determination of adenine released from ribosomes by ricin and gelonin. Biochem J 259:639-643.
-
(1989)
Biochem J
, vol.259
, pp. 639-643
-
-
Zamboni, M.1
Brigotti, M.2
Rambelli, F.3
Montanaro, L.4
Sperti, S.5
-
141
-
-
65249171997
-
Detecting ricin: Sensitive luminescent assay for ricin A-chain ribosome depurination kinetics
-
Sturm MB and Schramm VL. 2009. Detecting ricin: Sensitive luminescent assay for ricin A-chain ribosome depurination kinetics. Anal Chem 81:2847-2853.
-
(2009)
Anal Chem
, vol.81
, pp. 2847-2853
-
-
Sturm, M.B.1
Schramm, V.L.2
-
142
-
-
60049091766
-
The x-ray structure of ricin A chain with a novel inhibitor
-
Bai Y, Monzingo AF, and Robertus JD. 2009. The x-ray structure of ricin A chain with a novel inhibitor. Arch Biochem Biophys 483:23-28.
-
(2009)
Arch Biochem Biophys
, vol.483
, pp. 23-28
-
-
Bai, Y.1
Monzingo, A.F.2
Robertus, J.D.3
-
143
-
-
73449123743
-
A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin
-
Neal LM, O’Hara J, Brey RN, 3rd, and Mantis NJ. 2010. A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin. Infect Immun 78:552-561.
-
(2010)
Infect Immun
, vol.78
, pp. 552-561
-
-
Neal, L.M.1
O’Hara, J.2
Brey, R.N.3
Mantis, N.J.4
-
144
-
-
77954141743
-
Identification of small-molecule inhibitors of ricin and shiga toxin using a cell-based high-throughput screen
-
Wahome PG, Bai Y, Neal LM, Robertus JD, and Mantis NJ. 2010. Identification of small-molecule inhibitors of ricin and shiga toxin using a cell-based high-throughput screen. Toxicon 56:313-323.
-
(2010)
Toxicon
, vol.56
, pp. 313-323
-
-
Wahome, P.G.1
Bai, Y.2
Neal, L.M.3
Robertus, J.D.4
Mantis, N.J.5
-
145
-
-
84880671323
-
High-throughput, cell-based screens to identify small-molecule inhibitors of ricin toxin and related category b ribosome inactivating proteins (RIPs)
-
Chapter 2:Unit 2.23
-
Wahome PG and Mantis NJ. 2013. High-throughput, cell-based screens to identify small-molecule inhibitors of ricin toxin and related category b ribosome inactivating proteins (RIPs). Curr Protoc Toxicol Chapter 2:Unit 2.23.
-
(2013)
Curr Protoc Toxicol
-
-
Wahome, P.G.1
Mantis, N.J.2
-
146
-
-
84873527715
-
The need for continued development of ricin countermeasures
-
Reisler RB and Smith LA. 2012. The need for continued development of ricin countermeasures. Adv Prev Med 2012:149737.
-
(2012)
Adv Prev Med
, vol.2012
, pp. 149737
-
-
Reisler, R.B.1
Smith, L.A.2
-
148
-
-
0030294881
-
Structural analysis of ricin and implications for inhibitor design
-
Robertus JD, Yan X, Ernst S, Monzingo A, Worley S, Day P, Hollis T, and Svinth M. 1996. Structural analysis of ricin and implications for inhibitor design. Toxicon 34:1325-1334.
-
(1996)
Toxicon
, vol.34
, pp. 1325-1334
-
-
Robertus, J.D.1
Yan, X.2
Ernst, S.3
Monzingo, A.4
Worley, S.5
Day, P.6
Hollis, T.7
Svinth, M.8
-
149
-
-
0037011902
-
Structure-based design and characterization of novel platforms for ricin and shiga toxin inhibition
-
Miller DJ, Ravikumar K, Shen H, Suh JK, Kerwin SM, and Robertus JD. 2002. Structure-based design and characterization of novel platforms for ricin and shiga toxin inhibition. J Med Chem 45:90-98.
-
(2002)
J Med Chem
, vol.45
, pp. 90-98
-
-
Miller, D.J.1
Ravikumar, K.2
Shen, H.3
Suh, J.K.4
Kerwin, S.M.5
Robertus, J.D.6
-
150
-
-
80052924409
-
7-Substituted pterins provide a new direction for ricin A chain inhibitors
-
Pruet JM, Jasheway KR, Manzano LA, Bai Y, Anslyn EV, and Robertus JD. 2011. 7-Substituted pterins provide a new direction for ricin A chain inhibitors. Eur J Med Chem 46:3608-3615.
-
(2011)
Eur J Med Chem
, vol.46
, pp. 3608-3615
-
-
Pruet, J.M.1
Jasheway, K.R.2
Manzano, L.A.3
Bai, Y.4
Anslyn, E.V.5
Robertus, J.D.6
-
151
-
-
77955012685
-
Identification of new classes of ricin toxin inhibitors by virtual screening
-
Bai Y, Watt B, Wahome PG, Mantis NJ, and Robertus JD. 2010. Identification of new classes of ricin toxin inhibitors by virtual screening. Toxicon 56:526-534.
-
(2010)
Toxicon
, vol.56
, pp. 526-534
-
-
Bai, Y.1
Watt, B.2
Wahome, P.G.3
Mantis, N.J.4
Robertus, J.D.5
-
152
-
-
79953065234
-
Small-molecule inhibitor leads of ribosome-inactivating proteins developed using the doorstop approach
-
Pang YP, Park JG, Wang S, Vummenthala A, Mishra RK, McLaughlin JE, Di R, Kahn JN, Tumer NE, Janosi L, Davis J, and Millard CB. 2011. Small-molecule inhibitor leads of ribosome-inactivating proteins developed using the doorstop approach. PLoS One 6:e17883.
-
(2011)
PLoS One
, vol.6
-
-
Pang, Y.P.1
Park, J.G.2
Wang, S.3
Vummenthala, A.4
Mishra, R.K.5
McLaughlin, J.E.6
Di, R.7
Kahn, J.N.8
Tumer, N.E.9
Janosi, L.10
Davis, J.11
Millard, C.B.12
-
153
-
-
77951735286
-
Inhibition of retrograde transport protects mice from lethal ricin challenge
-
Stechmann B, Bai SK, Gobbo E, Lopez R, Merer G, Pinchard S, Panigai L et al. 2010. Inhibition of retrograde transport protects mice from lethal ricin challenge. Cell 141:231-242.
-
(2010)
Cell
, vol.141
, pp. 231-242
-
-
Stechmann, B.1
Bai, S.K.2
Gobbo, E.3
Lopez, R.4
Merer, G.5
Pinchard, S.6
Panigai, L.7
-
154
-
-
84868328200
-
Identification of small molecules that suppress ricin-induced stress-activated signaling pathways
-
Wahome PG, Ahlawat S, and Mantis NJ. 2012. Identification of small molecules that suppress ricin-induced stress-activated signaling pathways. PLoS One 7:e49075.
-
(2012)
PLoS One
, vol.7
-
-
Wahome, P.G.1
Ahlawat, S.2
Mantis, N.J.3
-
155
-
-
77749298671
-
A new model of bioterrorism risk assessment
-
Radosavljevic V and Belojevic G. 2009. A new model of bioterrorism risk assessment. Biosecur Bioterror 7:443-451.
-
(2009)
Biosecur Bioterror
, vol.7
, pp. 443-451
-
-
Radosavljevic, V.1
Belojevic, G.2
-
156
-
-
2442626550
-
Immunological characteristics associated with the protective efficacy of antibodies to ricin
-
Maddaloni M, Cooke C, Wilkinson R, Stout AV, Eng L, and Pincus SH. 2004. Immunological characteristics associated with the protective efficacy of antibodies to ricin. J Immunol 172:6221-6228.
-
(2004)
J Immunol
, vol.172
, pp. 6221-6228
-
-
Maddaloni, M.1
Cooke, C.2
Wilkinson, R.3
Stout, A.V.4
Eng, L.5
Pincus, S.H.6
-
157
-
-
80053636763
-
Protective immunity to ricin toxin conferred by antibodies against the toxin’s binding subunit (RTB)
-
Yermakova A and Mantis NJ. 2011. Protective immunity to ricin toxin conferred by antibodies against the toxin’s binding subunit (RTB). Vaccine 29:7925-7935.
-
(2011)
Vaccine
, vol.29
, pp. 7925-7935
-
-
Yermakova, A.1
Mantis, N.J.2
-
158
-
-
84867241458
-
A small phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine (RiVax)
-
Vitetta ES, Smallshaw JE, and Schindler J. 2012. A small phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine (RiVax). Clin Vaccine Immunol 19(10):1697-1699.
-
(2012)
Clin Vaccine Immunol
, vol.19
, Issue.10
, pp. 1697-1699
-
-
Vitetta, E.S.1
Smallshaw, J.E.2
Schindler, J.3
-
159
-
-
0037056037
-
A novel recombinant vaccine which protects mice against ricin intoxication
-
Smallshaw JE, Firan A, Fulmer JR, Ruback SL, Ghetie V, and Vitetta ES. 2002. A novel recombinant vaccine which protects mice against ricin intoxication. Vaccine 20:3422-3427.
-
(2002)
Vaccine
, vol.20
, pp. 3422-3427
-
-
Smallshaw, J.E.1
Firan, A.2
Fulmer, J.R.3
Ruback, S.L.4
Ghetie, V.5
Vitetta, E.S.6
-
160
-
-
0037382907
-
Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice
-
Smallshaw JE, Ghetie V, Rizo J, Fulmer JR, Trahan LL, Ghetie MA, and Vitetta ES. 2003. Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice. Nat Biotechnol 21:387-391.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 387-391
-
-
Smallshaw, J.E.1
Ghetie, V.2
Rizo, J.3
Fulmer, J.R.4
Trahan, L.L.5
Ghetie, M.A.6
Vitetta, E.S.7
-
161
-
-
34247326598
-
Improved formulation of a recombinant ricin A-chain vaccine increases its stability and effective antigenicity
-
Carra JH, Wannemacher RW, Tammariello RF, Lindsey CY, Dinterman RE, Schokman RD, and Smith LA. 2007. Improved formulation of a recombinant ricin A-chain vaccine increases its stability and effective antigenicity. Vaccine 25:4149-4158.
-
(2007)
Vaccine
, vol.25
, pp. 4149-4158
-
-
Carra, J.H.1
Wannemacher, R.W.2
Tammariello, R.F.3
Lindsey, C.Y.4
Dinterman, R.E.5
Schokman, R.D.6
Smith, L.A.7
-
162
-
-
4143060688
-
Improved stability of a protein vaccine through elimination of a partially unfolded state
-
McHugh CA, Tammariello RF, Millard CB, and Carra JH. 2004. Improved stability of a protein vaccine through elimination of a partially unfolded state. Protein Sci 13:2736-2743.
-
(2004)
Protein Sci
, vol.13
, pp. 2736-2743
-
-
McHugh, C.A.1
Tammariello, R.F.2
Millard, C.B.3
Carra, J.H.4
-
163
-
-
77957601374
-
Folding domains within the ricin toxin A subunit as targets of protective antibodies
-
O’Hara JM, Neal LM, McCarthy EA, Kasten-Jolly JA, Brey RN, 3rd, and Mantis NJ. 2010. Folding domains within the ricin toxin A subunit as targets of protective antibodies. Vaccine 28:7035-7046.
-
(2010)
Vaccine
, vol.28
, pp. 7035-7046
-
-
O’Hara, J.M.1
Neal, L.M.2
McCarthy, E.A.3
Kasten-Jolly, J.A.4
Brey, R.N.5
Mantis, N.J.6
-
164
-
-
77954958642
-
Intradermal administration of RiVax protects mice from mucosal and systemic ricin intoxication
-
Marconescu PS, Smallshaw JE, Pop LM, Ruback SL, and Vitetta ES. 2010. Intradermal administration of RiVax protects mice from mucosal and systemic ricin intoxication. Vaccine 28:5315-5322.
-
(2010)
Vaccine
, vol.28
, pp. 5315-5322
-
-
Marconescu, P.S.1
Smallshaw, J.E.2
Pop, L.M.3
Ruback, S.L.4
Vitetta, E.S.5
-
165
-
-
25144493280
-
Preclinical toxicity and efficacy testing of RiVax, a recombinant protein vaccine against ricin
-
Smallshaw JE, Richardson JA, Pincus S, Schindler J, and Vitetta ES. 2005. Preclinical toxicity and efficacy testing of RiVax, a recombinant protein vaccine against ricin. Vaccine 23:4775-4784.
-
(2005)
Vaccine
, vol.23
, pp. 4775-4784
-
-
Smallshaw, J.E.1
Richardson, J.A.2
Pincus, S.3
Schindler, J.4
Vitetta, E.S.5
-
166
-
-
33144473223
-
A pilot clinical trial of a recombinant ricin vaccine in normal humans
-
Vitetta ES, Smallshaw JE, Coleman E, Jafri H, Foster C, Munford R, and Schindler J. 2006. A pilot clinical trial of a recombinant ricin vaccine in normal humans. Proc Natl Acad Sci USA 103:2268-2273.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2268-2273
-
-
Vitetta, E.S.1
Smallshaw, J.E.2
Coleman, E.3
Jafri, H.4
Foster, C.5
Munford, R.6
Schindler, J.7
-
167
-
-
79955635252
-
Progress in biological threat agent vaccine development: A repeat-dose toxicity study of a recombinant ricin toxin a-chain (rRTA) 1-33/44-198 vaccine (RVEc) in male and female New Zealand White rabbits
-
McLain DE, Horn TL, Detrisac CJ, Lindsey CY, and Smith LA. 2011. Progress in biological threat agent vaccine development: A repeat-dose toxicity study of a recombinant ricin toxin a-chain (rRTA) 1-33/44-198 vaccine (RVEc) in male and female New Zealand White rabbits. Int J Toxicol 30(2):143-152.
-
(2011)
Int J Toxicol
, vol.30
, Issue.2
, pp. 143-152
-
-
McLain, D.E.1
Horn, T.L.2
Detrisac, C.J.3
Lindsey, C.Y.4
Smith, L.A.5
-
168
-
-
79961128084
-
Process development and cGMP manufacturing of a recombinant ricin vaccine: An effective and stable recombinant ricin a-chain vaccine-RVEc
-
Meagher MM, Seravalli JG, Swanson ST, Ladd RG, Khasa YP, Inan M, Harner JC et al. 2011. Process development and cGMP manufacturing of a recombinant ricin vaccine: An effective and stable recombinant ricin a-chain vaccine-RVEc. Biotechnol Prog 27(4):1036-1047.
-
(2011)
Biotechnol Prog
, vol.27
, Issue.4
, pp. 1036-1047
-
-
Meagher, M.M.1
Seravalli, J.G.2
Swanson, S.T.3
Ladd, R.G.4
Khasa, Y.P.5
Inan, M.6
Harner, J.C.7
-
169
-
-
79959374624
-
Evaluation of a ricin vaccine candidate (RVEc) for human toxicity using an in vitro vascular leak assay
-
Porter A, Phillips G, Smith L, Erwin-Cohen R, Tammariello R, Hale M, and Dasilva L. 2011. Evaluation of a ricin vaccine candidate (RVEc) for human toxicity using an in vitro vascular leak assay. Toxicon 58:68-75.
-
(2011)
Toxicon
, vol.58
, pp. 68-75
-
-
Porter, A.1
Phillips, G.2
Smith, L.3
Erwin-Cohen, R.4
Tammariello, R.5
Hale, M.6
Dasilva, L.7
-
170
-
-
0027497692
-
Monoclonal antibody prophylaxis against the in vivo toxicity of ricin in mice
-
Chanh TC, Romanowski MJ, and Hewetson JF. 1993. Monoclonal antibody prophylaxis against the in vivo toxicity of ricin in mice. Immunol Invest 22:63-72.
-
(1993)
Immunol Invest
, vol.22
, pp. 63-72
-
-
Chanh, T.C.1
Romanowski, M.J.2
Hewetson, J.F.3
-
171
-
-
79953308083
-
Identification of a novel functional domain of ricin responsible for its potent toxicity
-
Dai J, Zhao L, Yang H, Guo H, Fan K, Wang H, Qian W, Zhang D, Li B, and Guo Y. 2011. Identification of a novel functional domain of ricin responsible for its potent toxicity. J Biol Chem 286:12166-12171.
-
(2011)
J Biol Chem
, vol.286
, pp. 12166-12171
-
-
Dai, J.1
Zhao, L.2
Yang, H.3
Guo, H.4
Fan, K.5
Wang, H.6
Qian, W.7
Zhang, D.8
Li, B.9
Guo, Y.10
-
172
-
-
27144549591
-
Monoclonal antibodies to ricin: In vitro inhibition of toxicity and utility as diagnostic reagents
-
Dertzbaugh MT, Rossi CA, Paddle BM, Hale M, Poretski M, and Alderton MR. 2005. Monoclonal antibodies to ricin: In vitro inhibition of toxicity and utility as diagnostic reagents. Hybridoma (Larchmt) 24:236-243.
-
(2005)
Hybridoma (Larchmt)
, vol.24
, pp. 236-243
-
-
Dertzbaugh, M.T.1
Rossi, C.A.2
Paddle, B.M.3
Hale, M.4
Poretski, M.5
Alderton, M.R.6
-
173
-
-
0021985323
-
The use of anti-ricin antibodies to protect mice intoxicated with ricin
-
Foxwell BM, Detre SI, Donovan TA, and Thorpe PE. 1985. The use of anti-ricin antibodies to protect mice intoxicated with ricin. Toxicology 34:79-88.
-
(1985)
Toxicology
, vol.34
, pp. 79-88
-
-
Foxwell, B.M.1
Detre, S.I.2
Donovan, T.A.3
Thorpe, P.E.4
-
174
-
-
84857868612
-
General and local immunity to ricin
-
Hazen EL. 1927. General and local immunity to ricin. J Immunol 13:171-218.
-
(1927)
J Immunol
, vol.13
, pp. 171-218
-
-
Hazen, E.L.1
-
175
-
-
0027289275
-
Protection of mice from inhaled ricin by vaccination with ricin or by passive treatment with heterologous antibody
-
Hewetson JF, Rivera VR, Creasia DA, Lemley PV, Rippy MK, and Poli MA. 1993. Protection of mice from inhaled ricin by vaccination with ricin or by passive treatment with heterologous antibody. Vaccine 11:743-746.
-
(1993)
Vaccine
, vol.11
, pp. 743-746
-
-
Hewetson, J.F.1
Rivera, V.R.2
Creasia, D.A.3
Lemley, P.V.4
Rippy, M.K.5
Poli, M.A.6
-
176
-
-
0028927950
-
Protection against inhalation toxicity of ricin and abrin by immunisation
-
Griffiths GD, Lindsay CD, Allenby AC, Bailey SC, Scawin JW, Rice P, and Upshall DG. 1995. Protection against inhalation toxicity of ricin and abrin by immunisation. Hum Exp Toxicol 14:155-164.
-
(1995)
Hum Exp Toxicol
, vol.14
, pp. 155-164
-
-
Griffiths, G.D.1
Lindsay, C.D.2
Allenby, A.C.3
Bailey, S.C.4
Scawin, J.W.5
Rice, P.6
Upshall, D.G.7
-
177
-
-
0020600983
-
Antibody formation against the cytotoxic proteins abrin and ricin in humans and mice
-
Godal A, Fodstad O, and Pihl A. 1983. Antibody formation against the cytotoxic proteins abrin and ricin in humans and mice. Int J Cancer 32:515-521.
-
(1983)
Int J Cancer
, vol.32
, pp. 515-521
-
-
Godal, A.1
Fodstad, O.2
Pihl, A.3
-
178
-
-
0020455487
-
Protection of mice from ricin poisoning by treatment with antibodies directed against ricin
-
Houston LL. 1982. Protection of mice from ricin poisoning by treatment with antibodies directed against ricin. J Toxicol Clin Toxicol 19:385-389.
-
(1982)
J Toxicol Clin Toxicol
, vol.19
, pp. 385-389
-
-
Houston, L.L.1
-
179
-
-
0026692776
-
Mice are actively immunized after passive monoclonal antibody prophylaxis and ricin toxin challenge
-
Lemley PV and Wright DC. 1992. Mice are actively immunized after passive monoclonal antibody prophylaxis and ricin toxin challenge. Immunology 76:511-513.
-
(1992)
Immunology
, vol.76
, pp. 511-513
-
-
Lemley, P.V.1
Wright, D.C.2
-
180
-
-
0016789679
-
Conformation-dependent antigenic determinants in the toxic lectin ricin
-
Olsnes S and Saltvedt E. 1975. Conformation-dependent antigenic determinants in the toxic lectin ricin. J Immunol 114:1743-1748.
-
(1975)
J Immunol
, vol.114
, pp. 1743-1748
-
-
Olsnes, S.1
Saltvedt, E.2
-
181
-
-
79957476321
-
Neutralising antibodies against ricin toxin
-
Prigent J, Panigai L, Lamourette P, Sauvaire D, Devilliers K, Plaisance M, Volland H, Creminon C, and Simon S. 2011. Neutralising antibodies against ricin toxin. PLoS One 6:e20166.
-
(2011)
PLoS One
, vol.6
-
-
Prigent, J.1
Panigai, L.2
Lamourette, P.3
Sauvaire, D.4
Devilliers, K.5
Plaisance, M.6
Volland, H.7
Creminon, C.8
Simon, S.9
-
182
-
-
84866286563
-
Sub-domains of ricin’s B subunit as targets of toxin neutralizing and non-neutralizing monoclonal antibodies
-
Yermakova A, Vance DJ, and Mantis NJ. 2012. Sub-domains of ricin’s B subunit as targets of toxin neutralizing and non-neutralizing monoclonal antibodies. PLoS One 7:e44317.
-
(2012)
PLoS One
, vol.7
-
-
Yermakova, A.1
Vance, D.J.2
Mantis, N.J.3
-
183
-
-
84856567770
-
Plant-based expression of a partially humanized neutralizing monoclonal IgG directed against an immunodominant epitope on the ricin toxin A subunit
-
O’Hara JM, Whaley K, Pauly M, Zeitlin L, and Mantis NJ. 2012. Plant-based expression of a partially humanized neutralizing monoclonal IgG directed against an immunodominant epitope on the ricin toxin A subunit. Vaccine 30:1239-1243.
-
(2012)
Vaccine
, vol.30
, pp. 1239-1243
-
-
O’Hara, J.M.1
Whaley, K.2
Pauly, M.3
Zeitlin, L.4
Mantis, N.J.5
-
184
-
-
54949121317
-
Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model
-
Roche JK, Stone MK, Gross LK, Lindner M, Seaner R, Pincus SH, and Obrig TG. 2008. Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model. Lab Invest 88:1178-1191.
-
(2008)
Lab Invest
, vol.88
, pp. 1178-1191
-
-
Roche, J.K.1
Stone, M.K.2
Gross, L.K.3
Lindner, M.4
Seaner, R.5
Pincus, S.H.6
Obrig, T.G.7
|