Improved formulation of a recombinant ricin A-chain vaccine increases its stability and effective antigenicity

Vaccine

Volumn 25, Issue 21, 2007, Pages 4149-4158

  Carra, John H ^a   Wannemacher, Robert W ^a   Tammariello, Ralph F ^a   Lindsey, Changhong Y ^a   Dinterman, Richard E ^a   Schokman, Rowena D ^a   Smith, Leonard A ^a  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

Adjuvant adsorption; Ricin; Toxin

Indexed keywords

ALUMINUM HYDROXIDE; BUFFER; PHOSPHATE; RECOMBINANT RICIN A CHAIN VACCINE; SUCCINIC ACID; UNCLASSIFIED DRUG; VACCINE;

ACTIVE IMMUNIZATION; ADSORPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGENICITY; ARTICLE; CONTROLLED STUDY; DENATURATION; DRUG ADSORPTION; DRUG FORMULATION; DRUG POTENCY; DRUG STORAGE; FEMALE; INFRARED SPECTROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN STRUCTURE;

ADJUVANTS, IMMUNOLOGIC; ALUMINUM HYDROXIDE; ANIMALS; ANTITOXINS; CHEMISTRY, PHARMACEUTICAL; DISEASE MODELS, ANIMAL; DRUG STORAGE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; NEUTRALIZATION TESTS; POISONING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS; RICIN; SURVIVAL ANALYSIS; VACCINES, SYNTHETIC;

EID: 34247326598     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.03.011     Document Type: Article

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