Protein disulphide-isomerase reduces ricin to its A and B chains in the endoplasmic reticulum

Biochemical Journal

Volumn 383, Issue 2, 2004, Pages 285-293

  Spooner, Robert A ^a   Watson, Peter D ^a,b   Marsden, Catherine J ^a   Smith, Daniel C ^a   Moore, Katherine A H ^a   Cook, Jonathon P ^a   Lord, J Michael ^a   Roberts, Lynne M ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Endoplasmic reticulum associated protein degradation (ERAD); Oxidoreductase; Protein disulphide isomerase; Retrograde transport; Ricin; Toxin

Indexed keywords

CELLS; DIMERS; ENZYME KINETICS; ISOMERIZATION; REACTION KINETICS; TOXICITY;

CYTOTOXINS; ENDOPLASMIC RETICULUM; HETERODIMERS; INTOXICATION;

ENZYMES;

ABRIN; ABRIN B; CYTOTOXIN; DIMER; HOLOTOXIN; LECTIN; OXIDOREDUCTASE; PROTEIN DISULFIDE ISOMERASE; PROTEIN SUBUNIT; RICIN; RICIN A; RICIN B; UNCLASSIFIED DRUG;

ARTICLE; CELL PROTECTION; CYTOSOL; CYTOTOXICITY; DIMERIZATION; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TRANSPORT; RETROGRADE TRANSPORT; TOXICOKINETICS;

ABRIN; BIOLOGICAL TRANSPORT; DIMERIZATION; DISULFIDES; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; HELA CELLS; HUMANS; OXIDATION-REDUCTION; PEPTIDE HYDROLASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN DISULFIDE-ISOMERASE; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; RICIN; SULFHYDRYL COMPOUNDS;

EID: 7444241345     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20040742     Document Type: Article

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