Induction of cytokines by toxins that have an identical RNA N-glycosidase activity: Shiga toxin, ricin, and modeccin

Biochimica et Biophysica Acta - General Subjects

Volumn 1671, Issue 1-3, 2004, Pages 44-50

  Yamasaki, Chisato ^a   Nishikawa, Kiyotaka ^a,b   Zeng, Xun Ting ^a   Katayama, Yukie ^a   Natori, Yumiko ^a   Komatsu, Nobukazu ^c   Oda, Tatsuya ^c   Natori, Yasuhiro ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NAGASAKI UNIVERSITY   (Japan)

Author keywords

Colon epithelial cell; Cytokine; Modeccin; Ricin; RNA N glycosidase; Shiga toxin

Indexed keywords

BREFELDIN A; CELL PROTEIN; CYCLOHEXIMIDE; CYTOKINE; DIPHTHERIA TOXIN; GLYCOSIDASE; INTERLEUKIN 8; MODECCIN; N GLYCOSIDASE; PROTEIN INHIBITOR; RICIN; RNA; SHIGA TOXIN; TOXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARCINOMA CELL; CELL TRANSPORT; COLON ADENOCARCINOMA; CYTOKINE PRODUCTION; ENZYME ACTIVITY; GOLGI COMPLEX; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

ANIMALS; BREFELDIN A; CACO-2 CELLS; CERCOPITHECUS AETHIOPS; CYTOKINES; GLYCOLIPIDS; HUMANS; INTERLEUKIN-8; LACTOSE; LIPOSOMES; N-GLYCOSYL HYDROLASES; PLANT LECTINS; PROTEIN SUBUNITS; PROTEIN SYNTHESIS INHIBITORS; RICIN; SHIGA TOXIN; SPHINGOLIPIDS; VERO CELLS;

EID: 1542358177     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2004.01.002     Document Type: Article

References (35)

1. Li T.K., Fox B.S. Cholera toxin B subunit binding to an antigen-presenting cell directly co-stimulates cytokine production from a T cell clone. Int. Immunol. 8:1996;1849-1856.
2. Sommermeyer H., Resch K. Pertussis toxin B-subunit-induced Ca2(+)-fluxes in Jurkat human lymphoma cells: the action of long-term pre-treatment with cholera and pertussis holotoxins. Cell. Signal. 2:1990;115-128.
3. Lingwood A.C. Verotoxins and their glycolipid receptors. Adv. Lipid Res. 25:1993;189-211.
4. Endo Y., Tsurugi K., Yutsudo T., Takeda Y., Ogasawara T., Igarashi K. Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes: RNA N-glycosidase activity of the toxins. Eur. J. Biochem. 171:1988;45-50.
5. Saxena S.K., O'Brien A.D., Ackerman E.J. Shiga toxin, Shiga-like toxin II variant, and ricin are all single-site RNA N-glycosidases of 28S rRNA when microinjected into Xenopus oocytes. J. Biol. Chem. 264:1989;596-601.
6. Furutani M., Ito K., Oku Y., Takeda Y., Igarashi K. Demonstration of RNA N-glycosidase activity of a Vero toxin (VT2 variant) produced by Escherichia coli O91:H21 from a patient with the hemolytic uremic syndrome. Microb. Pathog. 34:1990;387-392.
7. Maloney M.D., Lingwood C.A. CD19 has a potential CD77 (globotriaosyl ceramide)-binding site with sequence similarity to verotoxin B-subunits: implications of molecular mimicry for B cell adhesion and enterohemorrhagic Escherichia coli pathogenesis. J. Exp. Med. 180:1994;191-201.
8. Acheson D.W.K. Effect of Shiga toxins on cytokine production from intestinal epithelial cells in tissue culture. Keusch G.T., Kawakami M. Cytokines, Cholera, and the Gut. 1996;67-73 IOS Press, Amsterdam.
9. Tesh V.L., Ramegowda B., Samuel J.E. Purified Shiga-like toxins induce expression of proinflammatory cytokines from murine peritoneal macrophages. Infect. Immun. 62:1994;5085-5094.
10. Thorpe C.M., Hurley B.P., Lincicome L.L., Jacewicz M.S., Keusch G.T., Acheson D.W. Shiga toxins stimulate secretion of interleukin-8 from intestinal epithelial cells. Infect. Immun. 67:1999;5985-5993.
11. Yamasaki C., Natori Yu., Zeng X.T., Ohmura M., Yamasaki S., Takeda Y., Natori Y. Induction of cytokines in a human colon epithelial cell line by Shiga toxin 1 (Stx1) and Stx2 but not by non-toxic mutant Stx1 which lacks N-glycosidase activity. FEBS Lett. 442:1999;231-234.
12. Stirpe F., Gasperi-Campani A., Barbieri L., Lorenzoni E., Montanaro L., Sperti S., Bonetti E. Inhibition of protein synthesis by modeccin, the toxin of Modecca digitata. FEBS Lett. 85:1977;65-67.
13. Endo Y., Tsurugi K. RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes. J. Biol. Chem. 262:1987;8128-8130.
14. Endo Y., Mitsui K., Motizuki M., Tsurugi K. The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28S ribosomal RNA caused by the toxins. J. Biol. Chem. 262:1987;5908-5912.
15. Olsnes S., Sandvig K., Madshus I.H., Sundan A. Entry mechanisms of protein toxins and picornaviruses. Biochem. Soc. Symp. 50:1985;171-191.
16. Melby E.L., Jacobsen J., Olsnes S., Sandvig K. Entry of protein toxins in polarized epithelial cells. Cancer Res. 53:1993;1755-1760.
17. Ohmura M., Yamasaki S., Kurazono H., Kashiwagi K., Igarashi K., Takeda Y. Characterization of non-toxic mutant toxins of Vero toxin 1 that were constructed by replacing amino acids in the A subunit. Microb. Pathog. 15:1993;169-176.
18. Oda T., Iwaoka J., Komatsu N., Muramatsu T. Involvement of N-acetylcysteine-sensitive pathways in ricin-induced apoptotic cell death in U937 cells. Biosci. Biotechnol. Biochem. 63:1999;341-348.
19. Nishikawa K., Matsuoka K., Kita E., Okabe N., Mizuguchi M., Hino K., Miyazawa S., Yamasaki C., Aoki J., Takashima S., Yamakawa Y., Nishijima M., Terunuma D., Kuzuhara H., Natori Y. A therapeutic agent with oriented carbohydrates for treatment of infections by Shiga toxin-producing Escherichia coli O157:H7. Proc. Natl. Acad. Sci. U. S. A. 99:2002;7669-7674.
20. Schuerer-Maly C.C., Eckmann L., Kagnoff M.F., Falco M.T., Maly F.E. Colonic epithelial cell lines as a source of interleukin-8: stimulation by inflammatory cytokines and bacterial lipopolysaccharide. Immunology. 81:1994;85-91.
21. Sandvig K., van Deurs B. Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives. EMBO J. 19:2000;5943-5950.
22. Wolff B., Zsak M., Rabeck C. Immunofluorescence assay for the quantitative and qualitative evaluation of intracellular interleukin-8 in microtiter plates. Anal. Biochem. 244:1997;33-39.
23. Colombatti M., Johnson V.G., Skopicki H.A., Fendley B., Lewis M.S., Youle R.J. Identification and characterization of a monoclonal antibody recognizing a galactose-binding domain of the toxin ricin. J. Immunol. 138:1987;3339-3344.
24. Magnusson S., Berg T., Turpin E., Frenoy J.P. Interactions of ricin with sinusoidal endothelial rat liver cells. Different involvement of two distinct carbohydrate-specific mechanisms in surface binding and internalization. Biochem. J. 277:1991;855-861.
25. Lindberg A.A., Brown J.E., Stromberg N., Westling-Ryd M., Schultz J.E., Karlsson K.-A. Identification of the carbohydrate receptor for Shiga toxin produced by Shigella dysenteriae type 1. J. Biol. Chem. 262:1987;1779-1785.
26. Perentesis J.P., Miller S.P., Bodley J.W. Protein toxin inhibitors of protein synthesis. BioFactors. 3:1992;173-184.
27. Bitzan M.M., Wang Y., Lin J., Marsden P.A. Verotoxin and ricin have novel effects on preproendothelin-1 expression but fail to modify nitric oxide synthase (ecNOS) expression and NO production in vascular endothelium. J. Clin. Invest. 101:1998;372-382.
28. Yoshida T., Chen C., Zhang M., Wu H.C. Disruption of the Golgi apparatus by brefeldin A inhibits the cytotoxicity of ricin, modeccin, and pseudomonas toxin. Exp. Cell Res. 192:1991;389-395.
29. Donta S.T., Tomicic T.K., Donohue-Rolfe A. Inhibition of Shiga-like toxins by brefeldin A. J. Infect. Dis. 171:1995;721-724.
30. Pudymaitis A., Armstrong G., Lingwood C.A. Verotoxin-resistant cell clones are deficient in the glycolipid globotriosylceramide: differential basis of phenotype. Arch. Biochem. Biophys. 286:1991;448-452.
31. Jacewicz M.S., Acheson D.W., Mobassaleh M., Donohue-Rolfe A., Balasubramanian K.A., Keusch G.T. Maturational regulation of globotriaosylceramide, the Shiga-like toxin 1 receptor, in cultured human gut epithelial cells. J. Clin. Invest. 96:1995;1328-1335.
32. Lord M.J., Jolliffe N.A., Marsden C.J., Pateman C.S., Smith D.C., Spooner R.A., Watson P.D., Roberts L.M. Ricin. Mechanisms of cytotoxicity. Toxic. Rev. 22:2003;53-64.
33. Karmali M.A. Infection by verocytotoxin-producing Escherichia coli. Clin. Microbiol. Rev. 2:1989;15-38.
34. Ruggenenti P., Lutz J., Remuzzi G. Pathogenesis and treatment of thrombotic microangiopathy. Kidney Inter., Suppl. 58:1997;S97-S101.
35. Brigotti M., Alfieri R., Sestili P., Bonelli M., Petronini P.G., Guidarelli A., Barbieri L., Stirpe F., Sperti S. Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells. FASEB J. 16:2002;365-372.