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Volumn , Issue , 2009, Pages 3-24

Regulation of Vulnerability to NMDA Excitotoxicity During Postnatal Maturation

Author keywords

Calcium; Death; Development; Hippocampus; Hypoxia; Ifenprodil; Ischemia; Membrane potential; Mitochondria; mtNOS; Nitric oxide; NOS; NR1; NR2A; NR2B; NVP AAM077

Indexed keywords


EID: 85145942686     PISSN: 2627535X     EISSN: 26275341     Source Type: Book Series    
DOI: 10.1007/978-1-60327-579-8_1     Document Type: Chapter
Times cited : (3)

References (153)
  • 1
    • 85145920243 scopus 로고
    • Anaerobic survival of adult animals
    • Fazekas JF, Himwich HE. Anaerobic survival of adult animals. Am J Physiol 1943; 139(3): 366–70.
    • (1943) Am J Physiol , vol.139 , Issue.3 , pp. 366-370
    • Fazekas, J.F.1    Himwich, H.E.2
  • 3
    • 0003189128 scopus 로고
    • The greater resistance of very young animals to arrest of the brain circulation
    • Kabat H. The greater resistance of very young animals to arrest of the brain circulation. Am J Physiol 1940;130(3):588–99.
    • (1940) Am J Physiol , vol.130 , Issue.3 , pp. 588-599
    • Kabat, H.1
  • 4
    • 0016467598 scopus 로고
    • Carbohydrate and energy metabolism in perinatal rat brain: Relation to survival in anoxia
    • Duffy TE, Kohle SJ, Vannucci RC. Carbohydrate and energy metabolism in perinatal rat brain: Relation to survival in anoxia. J Neurochem 1975;24(2):271–6.
    • (1975) J Neurochem , vol.24 , Issue.2 , pp. 271-276
    • Duffy, T.E.1    Kohle, S.J.2    Vannucci, R.C.3
  • 5
    • 0014682523 scopus 로고
    • Brain lesions in an infant rhesus monkey treated with monsodium glutamate
    • Olney JW, Sharpe LG. Brain lesions in an infant rhesus monkey treated with monsodium glutamate. Science 1969;166(903):386–8.
    • (1969) Science , vol.166 , Issue.903 , pp. 386-388
    • Olney, J.W.1    Sharpe, L.G.2
  • 6
    • 0023870521 scopus 로고
    • Pharmacology of glutamate neurotoxicity in cortical cell culture: Attenuation by NMDA antagonists
    • Choi DW, Koh J, Peters S. Pharmacology of glutamate neurotoxicity in cortical cell culture: Attenuation by NMDA antagonists. J Neurosci 1988;8:185–96.
    • (1988) J Neurosci , vol.8 , pp. 185-196
    • Choi, D.W.1    Koh, J.2    Peters, S.3
  • 7
    • 0023109409 scopus 로고
    • Glutamate neurotoxicity in cortical cell culture
    • Choi DW, Maulucci-Gedde M, Kriegstein AR. Glutamate neurotoxicity in cortical cell culture. J Neurosci 1987;7(2):357–68.
    • (1987) J Neurosci , vol.7 , Issue.2 , pp. 357-368
    • Choi, D.W.1    Maulucci-Gedde, M.2    Kriegstein, A.R.3
  • 8
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • Choi DW. Ionic dependence of glutamate neurotoxicity. J Neurosci 1987;7(2):369–79.
    • (1987) J Neurosci , vol.7 , Issue.2 , pp. 369-379
    • Choi, D.W.1
  • 9
    • 0024333640 scopus 로고
    • Hypobaric-ischemic conditions produce glutamate-like cytopathology in infant rat brain
    • Ikonomidou C, Price MT, Mosinger JL, et al. Hypobaric-ischemic conditions produce glutamate-like cytopathology in infant rat brain. J Neurosci 1989;9(5):1693–700.
    • (1989) J Neurosci , vol.9 , Issue.5 , pp. 1693-1700
    • Ikonomidou, C.1    Price, M.T.2    Mosinger, J.L.3
  • 10
    • 0024363138 scopus 로고
    • MK-801 prevents hypobaric-ischemic neuronal degeneration in infant rat brain
    • Olney JW, Ikonomidou C, Mosinger JL, Frierdich G. MK-801 prevents hypobaric-ischemic neuronal degeneration in infant rat brain. J Neurosci 1989;9(5):1701–4.
    • (1989) J Neurosci , vol.9 , Issue.5 , pp. 1701-1704
    • Olney, J.W.1    Ikonomidou, C.2    Mosinger, J.L.3    Frierdich, G.4
  • 11
    • 0023489906 scopus 로고
    • N-methyl-d-aspartate receptors mediate hypoxic neuronal injury in cortical culture
    • Goldberg MP, Weiss JH, Pham PC, Choi DW. N-methyl-d-aspartate receptors mediate hypoxic neuronal injury in cortical culture. J Pharmacol Exp Ther 1987;243(2):784–91.
    • (1987) J Pharmacol Exp Ther , vol.243 , Issue.2 , pp. 784-791
    • Goldberg, M.P.1    Weiss, J.H.2    Pham, P.C.3    Choi, D.W.4
  • 12
    • 0024342862 scopus 로고
    • Sensitivity of the developing rat brain to hypobaric/ischemic damage parallels sensitivity to N-methyl-aspartate neurotoxicity
    • Ikonomidou C, Mosinger JL, Salles KS, Labruyere J, Olney JW. Sensitivity of the developing rat brain to hypobaric/ischemic damage parallels sensitivity to N-methyl-aspartate neurotoxicity. J Neurosci 1989;9(8):2809–18.
    • (1989) J Neurosci , vol.9 , Issue.8 , pp. 2809-2818
    • Ikonomidou, C.1    Mosinger, J.L.2    Salles, K.S.3    Labruyere, J.4    Olney, J.W.5
  • 13
    • 0023752067 scopus 로고
    • Neurotoxicity of N-methyl-d-aspartate is markedly enhanced in developing rat central nervous system
    • McDonald JW, Silverstein FS, Johnston MV. Neurotoxicity of N-methyl-d-aspartate is markedly enhanced in developing rat central nervous system. Brain Res 1988;459(1):200–3.
    • (1988) Brain Res , vol.459 , Issue.1 , pp. 200-203
    • McDonald, J.W.1    Silverstein, F.S.2    Johnston, M.V.3
  • 14
    • 0026655623 scopus 로고
    • Regional expression of c-fos and heat shock protein-70 mRNA following hypoxia-ischemia in immature rat brain
    • Blumenfeld KS, Welsh FA, Harris VA, Pesenson MA. Regional expression of c-fos and heat shock protein-70 mRNA following hypoxia-ischemia in immature rat brain. J Cereb Blood Flow Metab 1992;12(6):987–95.
    • (1992) J Cereb Blood Flow Metab , vol.12 , Issue.6 , pp. 987-995
    • Blumenfeld, K.S.1    Welsh, F.A.2    Harris, V.A.3    Pesenson, M.A.4
  • 15
    • 0030799957 scopus 로고    scopus 로고
    • Influence of age on the cerebral lesions in an immature rat model of cerebral hypoxia-ischemia: A light microscopic study
    • Towfighi J, Mauger D, Vannucci RC, Vannucci SJ. Influence of age on the cerebral lesions in an immature rat model of cerebral hypoxia-ischemia: A light microscopic study. Dev Brain Res 1997;100(2):149–60.
    • (1997) Dev Brain Res , vol.100 , Issue.2 , pp. 149-160
    • Towfighi, J.1    Mauger, D.2    Vannucci, R.C.3    Vannucci, S.J.4
  • 16
    • 0032497124 scopus 로고    scopus 로고
    • Temporal evolution of neuronal changes in cerebral hypoxia-ischemia in developing rats: A quantitative light microscopic study
    • Towfighi J, Mauger D. Temporal evolution of neuronal changes in cerebral hypoxia-ischemia in developing rats: a quantitative light microscopic study. Dev Brain Res 1998;109(2):169–77.
    • (1998) Dev Brain Res , vol.109 , Issue.2 , pp. 169-177
    • Towfighi, J.1    Mauger, D.2
  • 17
    • 0030599566 scopus 로고    scopus 로고
    • Age-dependent effects of glutamate toxicity in the hippocampus
    • Liu Z, Stafstrom CE, Sarkisian M, et al. Age-dependent effects of glutamate toxicity in the hippocampus. Brain Res Dev Brain Res 1996;97(2):178–84.
    • (1996) Brain Res Dev Brain Res , vol.97 , Issue.2 , pp. 178-184
    • Liu, Z.1    Stafstrom, C.E.2    Sarkisian, M.3
  • 18
    • 33645010267 scopus 로고    scopus 로고
    • Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors
    • Zhou M, Baudry M. Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors. J Neurosci 2006;26(11):2956–63.
    • (2006) J Neurosci , vol.26 , Issue.11 , pp. 2956-2963
    • Zhou, M.1    Baudry, M.2
  • 19
    • 0029001816 scopus 로고
    • Preparative methods for brain slices: A discussion
    • Aitken PG, Breese GR, Dudek FF, et al. Preparative methods for brain slices: A discussion. J Neurosci Methods 1995;59(1):139–49.
    • (1995) J Neurosci Methods , vol.59 , Issue.1 , pp. 139-149
    • Aitken, P.G.1    Breese, G.R.2    Dudek, F.F.3
  • 20
    • 0029055205 scopus 로고
    • Making the best of brain slices; comparing preparative methods
    • Lipton P, Aitken PG, Dudek FE, et al. Making the best of brain slices; comparing preparative methods. J Neurosci Methods 1995;59(1):151–6.
    • (1995) J Neurosci Methods , vol.59 , Issue.1 , pp. 151-156
    • Lipton, P.1    Aitken, P.G.2    Dudek, F.E.3
  • 21
    • 0030599586 scopus 로고    scopus 로고
    • Vulnerability of CA1 neurons to glutamate is developmentally regulated
    • Marks JD, Friedman JE, Haddad GG. Vulnerability of CA1 neurons to glutamate is developmentally regulated. Brain Res Dev Brain Res 1996;97:194–206.
    • (1996) Brain Res Dev Brain Res , vol.97 , pp. 194-206
    • Marks, J.D.1    Friedman, J.E.2    Haddad, G.G.3
  • 22
    • 0034736080 scopus 로고    scopus 로고
    • Maturation of vulnerability to excitotoxicity: Intracellular mechanisms in cultured postnatal hippocampal neurons
    • Marks JD, Bindokas VP, Zhang XM. Maturation of vulnerability to excitotoxicity: Intracellular mechanisms in cultured postnatal hippocampal neurons. Brain Res Dev Brain Res 2000;124(1–2):101–16.
    • (2000) Brain Res Dev Brain Res , vol.124 , Issue.1-2 , pp. 101-116
    • Marks, J.D.1    Bindokas, V.P.2    Zhang, X.M.3
  • 23
    • 22244481826 scopus 로고    scopus 로고
    • Mitochondrial nitric oxide mediates decreased vulnerability of hippocampal neurons from immature animals to NMDA
    • Marks JD, Boriboun C, Wang J. Mitochondrial nitric oxide mediates decreased vulnerability of hippocampal neurons from immature animals to NMDA. J Neurosci 2005;25(28):6561–75.
    • (2005) J Neurosci , vol.25 , Issue.28 , pp. 6561-6575
    • Marks, J.D.1    Boriboun, C.2    Wang, J.3
  • 24
    • 0026093663 scopus 로고
    • Intracellular calcium concentrations during “chemical hypoxia” and excitotoxic neuronal injury
    • Dubinsky JM, Rothman SM. Intracellular calcium concentrations during “chemical hypoxia” and excitotoxic neuronal injury. J Neurosci 1991;11(8):2545–51.
    • (1991) J Neurosci , vol.11 , Issue.8 , pp. 2545-2551
    • Dubinsky, J.M.1    Rothman, S.M.2
  • 25
    • 0027497936 scopus 로고
    • Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons
    • Tymianski M, Charlton MP, Carlen PL, Tator CH. Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. J Neurosci 1993;13(5):2085–104.
    • (1993) J Neurosci , vol.13 , Issue.5 , pp. 2085-2104
    • Tymianski, M.1    Charlton, M.P.2    Carlen, P.L.3    Tator, C.H.4
  • 26
    • 0031792791 scopus 로고    scopus 로고
    • Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity
    • Sattler R, Charlton MP, Hafner M, Tymianski M. Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity. J Neurochem 1998;71(6): 2349–64.
    • (1998) J Neurochem , vol.71 , Issue.6 , pp. 2349-2364
    • Sattler, R.1    Charlton, M.P.2    Hafner, M.3    Tymianski, M.4
  • 27
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona M, Dypbukt JM, Bonfoco E, et al. Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function. Neuron 1995;15(4):961–73.
    • (1995) Neuron , vol.15 , Issue.4 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3
  • 29
    • 0032504708 scopus 로고    scopus 로고
    • Mitochondria and neuronal glutamate excitotoxicity
    • Nicholls DG, Budd SL. Mitochondria and neuronal glutamate excitotoxicity. Biochim Biophys Acta 1998;1366(1–2):97–112.
    • (1998) Biochim Biophys Acta , vol.1366 , Issue.1-2 , pp. 97-112
    • Nicholls, D.G.1    Budd, S.L.2
  • 31
    • 0033971898 scopus 로고    scopus 로고
    • Mitochondria and neuronal survival
    • Nicholls DG, Budd SL. Mitochondria and neuronal survival. Physiol Rev 2000;80(1):316–60.
    • (2000) Physiol Rev , vol.80 , Issue.1 , pp. 316-360
    • Nicholls, D.G.1    Budd, S.L.2
  • 32
    • 0024446688 scopus 로고
    • 2+ in cerebral cortex neurons is transient in immature cells but permanent in mature cells
    • 2+ in cerebral cortex neurons is transient in immature cells but permanent in mature cells. J Neurochem 1989;53(4):1316–19.
    • (1989) J Neurochem , vol.53 , Issue.4 , pp. 1316-1319
    • Wahl, P.1    Schousboe, A.2    Honore, T.3    Drejer, J.4
  • 33
    • 0024320852 scopus 로고
    • Development of excitotoxicity in cultured hippocampal neurons
    • Peterson C, Neal JH, Cotman CW. Development of excitotoxicity in cultured hippocampal neurons. Dev Brain Res 1989;48(2):187–95.
    • (1989) Dev Brain Res , vol.48 , Issue.2 , pp. 187-195
    • Peterson, C.1    Neal, J.H.2    Cotman, C.W.3
  • 34
    • 0025938452 scopus 로고
    • Developmental expression, compartmentalization, and possible role in excitotoxicity of a putative NMDA receptor protein in cultured hippocampal neurons
    • Mattson MP, Wang H, Michaelis EK. Developmental expression, compartmentalization, and possible role in excitotoxicity of a putative NMDA receptor protein in cultured hippocampal neurons. Brain Res 1991;565(1):94–108.
    • (1991) Brain Res , vol.565 , Issue.1 , pp. 94-108
    • Mattson, M.P.1    Wang, H.2    Michaelis, E.K.3
  • 35
    • 0029008636 scopus 로고
    • Developmental expression of N-methyl-d-aspartate (NMDA)-induced neurotoxicity, NMDA receptor function, and the NMDAR1 and glutamate-binding protein subunits in cerebellar granule cells in primary cultures
    • Xia Y, Ragan RE, Seah EE, Michaelis ML, Michaelis EK. Developmental expression of N-methyl-d-aspartate (NMDA)-induced neurotoxicity, NMDA receptor function, and the NMDAR1 and glutamate-binding protein subunits in cerebellar granule cells in primary cultures. Neurochem Res 1995;20(5):617–29.
    • (1995) Neurochem Res , vol.20 , Issue.5 , pp. 617-629
    • Xia, Y.1    Ragan, R.E.2    Seah, E.E.3    Michaelis, M.L.4    Michaelis, E.K.5
  • 37
    • 0028097733 scopus 로고
    • The quantity of calcium that appears to induce neuronal death
    • Eimerl S, Schramm M. The quantity of calcium that appears to induce neuronal death. J Neurochem 1994;62(3):1223–6.
    • (1994) J Neurochem , vol.62 , Issue.3 , pp. 1223-1226
    • Eimerl, S.1    Schramm, M.2
  • 38
    • 0032748413 scopus 로고    scopus 로고
    • 2+]i increases and NMDA receptor mRNA levels
    • 2+]i increases and NMDA receptor mRNA levels. Brain Res 1999;849(1–2):97–108.
    • (1999) Brain Res , vol.849 , Issue.1-2 , pp. 97-108
    • Cheng, C.1    Fass, D.M.2    Reynolds, I.J.3
  • 39
    • 34248233012 scopus 로고    scopus 로고
    • Increased vulnerability of hippocampal neurons with age in culture: Temporal association with increases in NMDA receptor current, NR2A subunit expression and recruitment of L-type calcium channels
    • Brewer LD, Thibault O, Staton J, et al. Increased vulnerability of hippocampal neurons with age in culture: Temporal association with increases in NMDA receptor current, NR2A subunit expression and recruitment of L-type calcium channels. Brain Res 2007;1151:20–31.
    • (2007) Brain Res , vol.1151 , pp. 20-31
    • Brewer, L.D.1    Thibault, O.2    Staton, J.3
  • 40
    • 18044376610 scopus 로고    scopus 로고
    • Changes in secondary glutamate release underlie the developmental regulation of excitotoxic neuronal cell death
    • Fogal B, Trettel J, Uliasz TF, Levine ES, Hewett SJ. Changes in secondary glutamate release underlie the developmental regulation of excitotoxic neuronal cell death. Neuroscience 2005;132(4):929–42.
    • (2005) Neuroscience , vol.132 , Issue.4 , pp. 929-942
    • Fogal, B.1    Trettel, J.2    Uliasz, T.F.3    Levine, E.S.4    Hewett, S.J.5
  • 42
    • 0032526807 scopus 로고    scopus 로고
    • Developmental regulation of the recovery process following glutamate-induced calcium rise in rodent primary neuronal cultures
    • Adamec E, Didier M, Nixon RA. Developmental regulation of the recovery process following glutamate-induced calcium rise in rodent primary neuronal cultures. Dev Brain Res 1998;108(1–2):101–10.
    • (1998) Dev Brain Res , vol.108 , Issue.1-2 , pp. 101-110
    • Adamec, E.1    Didier, M.2    Nixon, R.A.3
  • 43
    • 0026608995 scopus 로고
    • Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons
    • Randall RD, Thayer SA. Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J Neurosci 1992;12(5):1882–95.
    • (1992) J Neurosci , vol.12 , Issue.5 , pp. 1882-1895
    • Randall, R.D.1    Thayer, S.A.2
  • 44
    • 0032535275 scopus 로고    scopus 로고
    • Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells
    • Castilho RF, Hansson O, Ward MW, Budd SL, Nicholls DG. Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells. J Neurosci 1998;18(24): 10277–86.
    • (1998) J Neurosci , vol.18 , Issue.24 , pp. 10277-10286
    • Castilho, R.F.1    Hansson, O.2    Ward, M.W.3    Budd, S.L.4    Nicholls, D.G.5
  • 45
    • 0042035647 scopus 로고    scopus 로고
    • Interactions between mitochondrial bioenergetics and cytoplasmic calcium in cultured cerebellar granule cells
    • Nicholls DG, Vesce S, Kirk L, Chalmers S. Interactions between mitochondrial bioenergetics and cytoplasmic calcium in cultured cerebellar granule cells. Cell Calcium 2003;34(4–5): 407–24.
    • (2003) Cell Calcium , vol.34 , Issue.4-5 , pp. 407-424
    • Nicholls, D.G.1    Vesce, S.2    Kirk, L.3    Chalmers, S.4
  • 46
    • 0034254932 scopus 로고    scopus 로고
    • Delayed mitochondrial dysfunction in excitotoxic neuron death: Cytochrome c release and a secondary increase in superoxide production
    • Luetjens CM, Bui NT, Sengpiel B, et al. Delayed mitochondrial dysfunction in excitotoxic neuron death: Cytochrome c release and a secondary increase in superoxide production. J Neurosci 2000;20(15):5715–23.
    • (2000) J Neurosci , vol.20 , Issue.15 , pp. 5715-5723
    • Luetjens, C.M.1    Bui, N.T.2    Sengpiel, B.3
  • 47
    • 3342910554 scopus 로고    scopus 로고
    • Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury
    • Starkov AA, Chinopoulos C, Fiskum G. Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury. Cell Calcium 2004;36(3–4):257–64.
    • (2004) Cell Calcium , vol.36 , Issue.3-4 , pp. 257-264
    • Starkov, A.A.1    Chinopoulos, C.2    Fiskum, G.3
  • 48
    • 0023261234 scopus 로고
    • Delayed neurotoxicity of excitatory amino acids in vitro
    • Rothman SM, Thurston JH, Hauhart RE. Delayed neurotoxicity of excitatory amino acids in vitro. Neuroscience 1987;22(2):471–80.
    • (1987) Neuroscience , vol.22 , Issue.2 , pp. 471-480
    • Rothman, S.M.1    Thurston, J.H.2    Hauhart, R.E.3
  • 49
    • 0024431210 scopus 로고
    • Delayed rescue of N-methyl-d-aspartate receptor-mediated neuronal injury in cortical culture
    • Hartley DM, Choi DW. Delayed rescue of N-methyl-d-aspartate receptor-mediated neuronal injury in cortical culture. J Pharmacol Exp Ther 1989;250(2):752–8.
    • (1989) J Pharmacol Exp Ther , vol.250 , Issue.2 , pp. 752-758
    • Hartley, D.M.1    Choi, D.W.2
  • 50
    • 33751221592 scopus 로고    scopus 로고
    • Electrophysiological mechanisms of delayed excitotoxicity: Positive feedback loop between NMDA receptor current and depolarization-mediated glutamate release
    • Norris CM, Blalock EM, Thibault O, et al. Electrophysiological mechanisms of delayed excitotoxicity: Positive feedback loop between NMDA receptor current and depolarization-mediated glutamate release. J Neurophysiol 2006;96(5):2488–500.
    • (2006) J Neurophysiol , vol.96 , Issue.5 , pp. 2488-2500
    • Norris, C.M.1    Blalock, E.M.2    Thibault, O.3
  • 51
    • 0023475388 scopus 로고
    • Rat brain N-methyl-d-aspartate receptors expressed in Xenopus oocytes
    • Verdoorn TA, Kleckner NW, Dingledine R. Rat brain N-methyl-d-aspartate receptors expressed in Xenopus oocytes. Science 1987;238(4830):1114–16.
    • (1987) Science , vol.238 , Issue.4830 , pp. 1114-1116
    • Verdoorn, T.A.1    Kleckner, N.W.2    Dingledine, R.3
  • 52
    • 12144257176 scopus 로고    scopus 로고
    • The micromolar zinc-binding domain on the NMDA receptor subunit NR2B
    • Rachline J, Perin-Dureau F, Le Goff A, Neyton J, Paoletti P. The micromolar zinc-binding domain on the NMDA receptor subunit NR2B. J Neurosci 2005;25(2):308–17.
    • (2005) J Neurosci , vol.25 , Issue.2 , pp. 308-317
    • Rachline, J.1    Perin-Dureau, F.2    Le Goff, A.3    Neyton, J.4    Paoletti, P.5
  • 53
    • 0025694769 scopus 로고
    • Polyamines potentiate responses of N-methyl-d-aspartate receptors expressed in xenopus oocytes
    • McGurk JF, Bennett MV, Zukin RS. Polyamines potentiate responses of N-methyl-d-aspartate receptors expressed in xenopus oocytes. Proc Natl Acad Sci USA 1990;87(24):9971–4.
    • (1990) Proc Natl Acad Sci USA , vol.87 , Issue.24 , pp. 9971-9974
    • McGurk, J.F.1    Bennett, M.V.2    Zukin, R.S.3
  • 54
    • 0026082757 scopus 로고
    • + sensitivity of excitatory amino acid receptor channels in rat cerebellar granule neurones
    • + sensitivity of excitatory amino acid receptor channels in rat cerebellar granule neurones. J Physiol 1991;433:727–63.
    • (1991) J Physiol , vol.433 , pp. 727-763
    • Traynelis, S.F.1    Cull-Candy, S.G.2
  • 55
    • 0024623852 scopus 로고
    • Selective modulation of NMDA responses by reduction and oxidation
    • Aizenman E, Lipton SA, Loring RH. Selective modulation of NMDA responses by reduction and oxidation. Neuron 1989;2(3):1257–63.
    • (1989) Neuron , vol.2 , Issue.3 , pp. 1257-1263
    • Aizenman, E.1    Lipton, S.A.2    Loring, R.H.3
  • 56
    • 8544244897 scopus 로고    scopus 로고
    • Postsynaptic density protein-95 regulates NMDA channel gating and surface expression
    • Lin Y, Skeberdis VA, Francesconi A, Bennett MVL, Zukin RS. Postsynaptic density protein-95 regulates NMDA channel gating and surface expression. J Neurosci 2004;24(45):10138–48.
    • (2004) J Neurosci , vol.24 , Issue.45 , pp. 10138-10148
    • Lin, Y.1    Skeberdis, V.A.2    Francesconi, A.3    Bennett, M.V.L.4    Zukin, R.S.5
  • 57
    • 0035369112 scopus 로고    scopus 로고
    • NMDA receptor subunits: Diversity, development and disease
    • Cull-Candy S, Brickley S, Farrant M. NMDA receptor subunits: Diversity, development and disease. Curr Opin Neurobiol 2001;11(3):327–35.
    • (2001) Curr Opin Neurobiol , vol.11 , Issue.3 , pp. 327-335
    • Cull-Candy, S.1    Brickley, S.2    Farrant, M.3
  • 58
    • 17744387125 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor structure and pharmacology
    • Kew JN, Kemp JA. Ionotropic and metabotropic glutamate receptor structure and pharmacology. Psychopharmacology 2005;179(1):4–29.
    • (2005) Psychopharmacology , vol.179 , Issue.1 , pp. 4-29
    • Kew, J.N.1    Kemp, J.A.2
  • 59
    • 0025974234 scopus 로고
    • Kinetic analysis of antagonist action at N-methyl-d-aspartic acid receptors. Two binding sites each for glutamate and glycine
    • Benveniste M, Mayer ML. Kinetic analysis of antagonist action at N-methyl-d-aspartic acid receptors. Two binding sites each for glutamate and glycine. Biophys J 1991;59(3): 560–73.
    • (1991) Biophys J , vol.59 , Issue.3 , pp. 560-573
    • Benveniste, M.1    Mayer, M.L.2
  • 60
    • 0025944430 scopus 로고
    • Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-d-aspartate receptor
    • Clements JD, Westbrook GL. Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-d-aspartate receptor. Neuron 1991;7(4):605–13.
    • (1991) Neuron , vol.7 , Issue.4 , pp. 605-613
    • Clements, J.D.1    Westbrook, G.L.2
  • 61
    • 2642598047 scopus 로고    scopus 로고
    • Functional and pharmacological differences between recombinant N-methyl-d-aspartate receptors
    • Vicini S, Wang JF, Li JH, et al. Functional and pharmacological differences between recombinant N-methyl-d-aspartate receptors. J Neurophysiol 1998;79(2):555–66.
    • (1998) J Neurophysiol , vol.79 , Issue.2 , pp. 555-566
    • Vicini, S.1    Wang, J.F.2    Li, J.H.3
  • 62
    • 0000737948 scopus 로고    scopus 로고
    • Activation of single AMPA-and NMDA-type glutamate receptor channels
    • Jonas P, Monyer H, eds. , Berlin: Springer
    • Behe P, Colquhoun D, Wyllie DJA. Activation of single AMPA-and NMDA-type glutamate receptor channels. In: Jonas P, Monyer H, eds. Ionotropic glutamate receptors in the CNS. Berlin: Springer; 1999:175–218.
    • (1999) Ionotropic Glutamate Receptors in the CNS , pp. 175-218
    • Behe, P.1    Colquhoun, D.2    Wyllie, D.J.A.3
  • 63
    • 0037074985 scopus 로고    scopus 로고
    • Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits
    • Chatterton JE, Awobuluyi M, Premkumar LS, et al. Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits. Nature 2002;415(6873):793–8.
    • (2002) Nature , vol.415 , Issue.6873 , pp. 793-798
    • Chatterton, J.E.1    Awobuluyi, M.2    Premkumar, L.S.3
  • 64
    • 0028810181 scopus 로고
    • Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain
    • Sucher NJ, Akbarian S, Chi CL, et al. Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain. J Neurosci 1995;15(10):6509–20.
    • (1995) J Neurosci , vol.15 , Issue.10 , pp. 6509-6520
    • Sucher, N.J.1    Akbarian, S.2    Chi, C.L.3
  • 65
    • 0028973158 scopus 로고
    • Cloning and characterization of chi-1: A developmentally regulated member of a novel class of the ionotropic glutamate receptor family
    • Ciabarra AM, Sullivan JM, Gahn LG, Pecht G, Heinemann S, Sevarino KA. Cloning and characterization of chi-1: A developmentally regulated member of a novel class of the ionotropic glutamate receptor family. J Neurosci 1995;15(10):6498–508.
    • (1995) J Neurosci , vol.15 , Issue.10 , pp. 6498-6508
    • Ciabarra, A.M.1    Sullivan, J.M.2    Gahn, L.G.3    Pecht, G.4    Heinemann, S.5    Sevarino, K.A.6
  • 66
    • 0035650937 scopus 로고    scopus 로고
    • Motoneuron-specific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner
    • Nishi M, Hinds H, Lu H-P, Kawata M, Hayashi Y. Motoneuron-specific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner. J Neurosci 2001;21(23):185RC.
    • (2001) J Neurosci , vol.21 , Issue.23 , pp. 185RC
    • Nishi, M.1    Hinds, H.2    Lu, H.-P.3    Kawata, M.4    Hayashi, Y.5
  • 67
    • 0242526137 scopus 로고    scopus 로고
    • Specific assembly with the NMDA receptor 3B subunit controls surface expression and calcium permeability of NMDA receptors
    • Matsuda K, Fletcher M, Kamiya Y, Yuzaki M. Specific assembly with the NMDA receptor 3B subunit controls surface expression and calcium permeability of NMDA receptors. J Neurosci 2003;23(31):10064–73.
    • (2003) J Neurosci , vol.23 , Issue.31 , pp. 10064-10073
    • Matsuda, K.1    Fletcher, M.2    Kamiya, Y.3    Yuzaki, M.4
  • 68
    • 0032575065 scopus 로고    scopus 로고
    • Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A
    • Das S, Sasaki YF, Rothe T, et al. Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A. Nature 1998;393(6683):377–81.
    • (1998) Nature , vol.393 , Issue.6683 , pp. 377-381
    • Das, S.1    Sasaki, Y.F.2    Rothe, T.3
  • 69
    • 0032234177 scopus 로고    scopus 로고
    • Phenylethanolamines inhibit NMDA receptors by enhancing proton inhibition
    • Mott DD, Doherty JJ, Zhang S, et al. Phenylethanolamines inhibit NMDA receptors by enhancing proton inhibition. Nat Neurosci 1998;1(8):659–67.
    • (1998) Nat Neurosci , vol.1 , Issue.8 , pp. 659-667
    • Mott, D.D.1    Doherty, J.J.2    Zhang, S.3
  • 70
    • 0027525324 scopus 로고
    • Ifenprodil discriminates subtypes of the N-methyl-d-aspartate receptor: Selectivity and mechanisms at recombinant heteromeric receptors
    • Williams K. Ifenprodil discriminates subtypes of the N-methyl-d-aspartate receptor: Selectivity and mechanisms at recombinant heteromeric receptors. Mol Pharmacol 1993;44(4):851–9.
    • (1993) Mol Pharmacol , vol.44 , Issue.4 , pp. 851-859
    • Williams, K.1
  • 71
    • 32544450453 scopus 로고    scopus 로고
    • Relating NMDA receptor function to receptor subunit composition: Limitations of the pharmacological approach
    • Neyton J, Paoletti P. Relating NMDA receptor function to receptor subunit composition: Limitations of the pharmacological approach. J Neurosci 2006;26(5):1331–3.
    • (2006) J Neurosci , vol.26 , Issue.5 , pp. 1331-1333
    • Neyton, J.1    Paoletti, P.2
  • 72
    • 0037041183 scopus 로고    scopus 로고
    • 5-Phosphono-methylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition
    • Auberson YP, Allgeier H, Bischoff S, Lingenhoehl K, Moretti R, Schmutz M. 5-Phosphono-methylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. Bioorg Med Chem Lett 2002; 12(7):1099–102.
    • (2002) Bioorg Med Chem Lett , vol.12 , Issue.7 , pp. 1099-1102
    • Auberson, Y.P.1    Allgeier, H.2    Bischoff, S.3    Lingenhoehl, K.4    Moretti, R.5    Schmutz, M.6
  • 73
    • 0030997418 scopus 로고    scopus 로고
    • Differential sensitivity of recombinant N-methyl-d-aspartate receptor subtypes to zinc inhibition
    • Chen N, Moshaver A, Raymond LA. Differential sensitivity of recombinant N-methyl-d-aspartate receptor subtypes to zinc inhibition. Mol Pharmacol 1997;51(6):1015–23.
    • (1997) Mol Pharmacol , vol.51 , Issue.6 , pp. 1015-1023
    • Chen, N.1    Moshaver, A.2    Raymond, L.A.3
  • 74
    • 17444426068 scopus 로고    scopus 로고
    • Modulation of triheteromeric NMDA receptors by N-terminal domain ligands
    • Hatton CJ, Paoletti P. Modulation of triheteromeric NMDA receptors by N-terminal domain ligands. Neuron 2005;46(2):261–74.
    • (2005) Neuron , vol.46 , Issue.2 , pp. 261-274
    • Hatton, C.J.1    Paoletti, P.2
  • 75
    • 33748921093 scopus 로고    scopus 로고
    • NMDA receptor function: Subunit composition versus spatial distribution
    • Köhr G. NMDA receptor function: Subunit composition versus spatial distribution. Cell Tissue Res 2006;326(2):439–46.
    • (2006) Cell Tissue Res , vol.326 , Issue.2 , pp. 439-446
    • Köhr, G.1
  • 76
    • 0029075591 scopus 로고
    • Characterization of NMDA receptor subunit-specific antibodies: Distribution of NR2A and NR2B receptor subunits in rat brain and ontogenic profile in the cerebellum
    • Wang YH, Bosy TZ, Yasuda RP, et al. Characterization of NMDA receptor subunit-specific antibodies: Distribution of NR2A and NR2B receptor subunits in rat brain and ontogenic profile in the cerebellum. J Neurochem 1995;65(1):176–83.
    • (1995) J Neurochem , vol.65 , Issue.1 , pp. 176-183
    • Wang, Y.H.1    Bosy, T.Z.2    Yasuda, R.P.3
  • 77
    • 0029552595 scopus 로고
    • Distribution of NMDA receptor subunit proteins NR2A, 2B, 2C and 2D in rat brain
    • Wenzel A, Scheurer L, Kunzi R, Fritschy JM, Mohler H, Benke D. Distribution of NMDA receptor subunit proteins NR2A, 2B, 2C and 2D in rat brain. Neuroreport 1995;7(1):45–8.
    • (1995) Neuroreport , vol.7 , Issue.1 , pp. 45-48
    • Wenzel, A.1    Scheurer, L.2    Kunzi, R.3    Fritschy, J.M.4    Mohler, H.5    Benke, D.6
  • 78
    • 0023227489 scopus 로고
    • NMDA receptors in the visual cortex of young kittens are more effective than those of adult cats
    • Tsumoto T, Hagihara K, Sato H, Hata Y. NMDA receptors in the visual cortex of young kittens are more effective than those of adult cats. Nature 1987;327(6122):513–14.
    • (1987) Nature , vol.327 , Issue.6122 , pp. 513-514
    • Tsumoto, T.1    Hagihara, K.2    Sato, H.3    Hata, Y.4
  • 79
    • 0026770417 scopus 로고
    • Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse
    • Hestrin S. Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse. Nature 1992;357(6380):686–9.
    • (1992) Nature , vol.357 , Issue.6380 , pp. 686-689
    • Hestrin, S.1
  • 80
    • 0028219211 scopus 로고
    • Changing subunit composition of heteromeric NMDA receptors during development of rat cortex
    • Sheng M, Cummings J, Roldan LA, Jan YN, Jan LY. Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature 1994;368(6467):144–7.
    • (1994) Nature , vol.368 , Issue.6467 , pp. 144-147
    • Sheng, M.1    Cummings, J.2    Roldan, L.A.3    Jan, Y.N.4    Jan, L.Y.5
  • 81
    • 0028343648 scopus 로고
    • Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
    • Monyer H, Burnashev N, Laurie DJ, Sakmann B, Seeburg PH. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 1994; 12(3):529–40.
    • (1994) Neuron , vol.12 , Issue.3 , pp. 529-540
    • Monyer, H.1    Burnashev, N.2    Laurie, D.J.3    Sakmann, B.4    Seeburg, P.H.5
  • 82
    • 0029670633 scopus 로고    scopus 로고
    • N-methyl-d-aspartate receptor proteins NR2A and NR2B are differentially distributed in the developing rat central nervous system as revealed by subunit-specific antibodies
    • Portera-Cailliau C, Price DL, Martin LJ. N-methyl-d-aspartate receptor proteins NR2A and NR2B are differentially distributed in the developing rat central nervous system as revealed by subunit-specific antibodies. J Neurochem 1996;66(2):692–700.
    • (1996) J Neurochem , vol.66 , Issue.2 , pp. 692-700
    • Portera-Cailliau, C.1    Price, D.L.2    Martin, L.J.3
  • 83
    • 0141502156 scopus 로고    scopus 로고
    • Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation
    • Law AJ, Weickert CS, Webster MJ, Herman MM, Kleinman JE, Harrison PJ. Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation. Eur J Neurosci 2003;18(5):1197–205.
    • (2003) Eur J Neurosci , vol.18 , Issue.5 , pp. 1197-1205
    • Law, A.J.1    Weickert, C.S.2    Webster, M.J.3    Herman, M.M.4    Kleinman, J.E.5    Harrison, P.J.6
  • 84
    • 0025739363 scopus 로고
    • Regulation of hippocampal NMDA receptors by magnesium and glycine during development
    • Kleckner NW, Dingledine R. Regulation of hippocampal NMDA receptors by magnesium and glycine during development. Mol Brain Res 1991;11(2):151–9.
    • (1991) Mol Brain Res , vol.11 , Issue.2 , pp. 151-159
    • Kleckner, N.W.1    Dingledine, R.2
  • 85
    • 0035115494 scopus 로고    scopus 로고
    • NMDAR EPSC kinetics do not regulate the critical period for LTP at thalamocortical synapses
    • Barth AL, Malenka RC. NMDAR EPSC kinetics do not regulate the critical period for LTP at thalamocortical synapses. Nat Neurosci 2001;4(3):235–6.
    • (2001) Nat Neurosci , vol.4 , Issue.3 , pp. 235-236
    • Barth, A.L.1    Malenka, R.C.2
  • 86
    • 0035923751 scopus 로고    scopus 로고
    • Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition
    • Lu H-C, Gonzalez E, Crair MC. Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition. Neuron 2001;32(4):619–34.
    • (2001) Neuron , vol.32 , Issue.4 , pp. 619-634
    • Lu, H.-C.1    Gonzalez, E.2    Crair, M.C.3
  • 87
    • 0037417988 scopus 로고    scopus 로고
    • Developmental loss of miniature N-methyl-d-aspartate receptor currents in NR2A knockout mice
    • Townsend M, Yoshii A, Mishina M, Constantine-Paton M. Developmental loss of miniature N-methyl-d-aspartate receptor currents in NR2A knockout mice. Proc Natl Acad Sci USA 2003;100(3):1340–5.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.3 , pp. 1340-1345
    • Townsend, M.1    Yoshii, A.2    Mishina, M.3    Constantine-Paton, M.4
  • 88
    • 0027405347 scopus 로고
    • Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro
    • Williams K, Russell SL, Shen YM, Molinoff PB. Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro. Neuron 1993;10(2):267–78.
    • (1993) Neuron , vol.10 , Issue.2 , pp. 267-278
    • Williams, K.1    Russell, S.L.2    Shen, Y.M.3    Molinoff, P.B.4
  • 89
    • 4544373236 scopus 로고    scopus 로고
    • Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression
    • Massey PV, Johnson BE, Moult PR, et al. Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression. J Neurosci 2004;24(36):7821–8.
    • (2004) J Neurosci , vol.24 , Issue.36 , pp. 7821-7828
    • Massey, P.V.1    Johnson, B.E.2    Moult, P.R.3
  • 90
    • 2342637165 scopus 로고    scopus 로고
    • Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity
    • Liu L, Wong TP, Pozza MF, et al. Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity. Science 2004;304(5673):1021–4.
    • (2004) Science , vol.304 , Issue.5673 , pp. 1021-1024
    • Liu, L.1    Wong, T.P.2    Pozza, M.F.3
  • 91
    • 0344198020 scopus 로고    scopus 로고
    • Intracellular domains of NMDA receptor subtypes are determinants for long-term potentiation induction
    • Kohr G, Jensen V, Koester HJ, et al. Intracellular domains of NMDA receptor subtypes are determinants for long-term potentiation induction. J Neurosci 2003;23(34):10791–9.
    • (2003) J Neurosci , vol.23 , Issue.34 , pp. 10791-10799
    • Kohr, G.1    Jensen, V.2    Koester, H.J.3
  • 92
    • 33645061251 scopus 로고    scopus 로고
    • Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition
    • DeRidder MN, Simon MJ, Siman R, Auberson YP, Raghupathi R, Meaney DF. Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition. Neurobiol Dis 2006;22(1): 165–76.
    • (2006) Neurobiol Dis , vol.22 , Issue.1 , pp. 165-176
    • Deridder, M.N.1    Simon, M.J.2    Siman, R.3    Auberson, Y.P.4    Raghupathi, R.5    Meaney, D.F.6
  • 93
    • 34547228856 scopus 로고    scopus 로고
    • Excitotoxicity in vitro by NR2A-and NR2B-containing NMDA receptors
    • von Engelhardt J, Coserea I, Pawlak V, et al. Excitotoxicity in vitro by NR2A-and NR2B-containing NMDA receptors. Neuropharmacology 2007;53(1):10–17.
    • (2007) Neuropharmacology , vol.53 , Issue.1 , pp. 10-17
    • von Engelhardt, J.1    Coserea, I.2    Pawlak, V.3
  • 94
    • 0032559283 scopus 로고    scopus 로고
    • Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo
    • Sprengel R, Suchanek B, Amico C, et al. Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo. Cell 1998;92(2):279–89.
    • (1998) Cell , vol.92 , Issue.2 , pp. 279-289
    • Sprengel, R.1    Suchanek, B.2    Amico, C.3
  • 95
    • 2342455195 scopus 로고    scopus 로고
    • Controlling the ups and downs of synaptic strength
    • Bliss T, Schoepfer R. Neuroscience. Controlling the ups and downs of synaptic strength. Science 2004;304(5673):973–4.
    • (2004) Science , vol.304 , Issue.5673 , pp. 973-974
    • Bliss, T.1    Neuroscience, S.R.2
  • 96
    • 33947331063 scopus 로고    scopus 로고
    • NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo
    • Liu Y, Wong TP, Aarts M, et al. NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo. J Neurosci 2007;27(11):2846–57.
    • (2007) J Neurosci , vol.27 , Issue.11 , pp. 2846-2857
    • Liu, Y.1    Wong, T.P.2    Aarts, M.3
  • 97
    • 0033562610 scopus 로고    scopus 로고
    • The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro
    • Tovar KR, Westbrook GL. The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro. J Neurosci 1999;19(10):4180–8.
    • (1999) J Neurosci , vol.19 , Issue.10 , pp. 4180-4188
    • Tovar, K.R.1    Westbrook, G.L.2
  • 98
    • 0036241207 scopus 로고    scopus 로고
    • Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
    • Hardingham GE, Fukunaga Y, Bading H. Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways. Nat Neurosci 2002;5(5):405–14.
    • (2002) Nat Neurosci , vol.5 , Issue.5 , pp. 405-414
    • Hardingham, G.E.1    Fukunaga, Y.2    Bading, H.3
  • 99
    • 33846847943 scopus 로고    scopus 로고
    • Decoding NMDA receptor signaling: Identification of genomic programs specifying neuronal survival and death
    • Zhang SJ, Steijaert MN, Lau D, et al. Decoding NMDA receptor signaling: Identification of genomic programs specifying neuronal survival and death. Neuron 2007;53(4):549–62.
    • (2007) Neuron , vol.53 , Issue.4 , pp. 549-562
    • Zhang, S.J.1    Steijaert, M.N.2    Lau, D.3
  • 100
    • 0031844719 scopus 로고    scopus 로고
    • Developmental changes in localization of NMDA receptor subunits in primary cultures of cortical neurons
    • Li JH, Wang YH, Wolfe BB, et al. Developmental changes in localization of NMDA receptor subunits in primary cultures of cortical neurons. Eur J Neurosci 1998;10(5):1704–15.
    • (1998) Eur J Neurosci , vol.10 , Issue.5 , pp. 1704-1715
    • Li, J.H.1    Wang, Y.H.2    Wolfe, B.B.3
  • 101
    • 0032520191 scopus 로고    scopus 로고
    • Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture
    • Rao A, Kim E, Sheng M, Craig AM. Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture. J Neurosci 1998;18(4):1217–29.
    • (1998) J Neurosci , vol.18 , Issue.4 , pp. 1217-1229
    • Rao, A.1    Kim, E.2    Sheng, M.3    Craig, A.M.4
  • 102
    • 0025218770 scopus 로고
    • Excitotoxicity induced by enhanced excitatory neurotransmission in cultured hippocampal pyramidal neurons
    • Abele AE, Scholz KP, Scholz WK, Miller RJ. Excitotoxicity induced by enhanced excitatory neurotransmission in cultured hippocampal pyramidal neurons. Neuron 1990;4(3):413–19.
    • (1990) Neuron , vol.4 , Issue.3 , pp. 413-419
    • Abele, A.E.1    Scholz, K.P.2    Scholz, W.K.3    Miller, R.J.4
  • 103
    • 0025390880 scopus 로고
    • Protection against ischaemic neuronal damage by drugs acting on excitatory neurotransmission
    • Meldrum B. Protection against ischaemic neuronal damage by drugs acting on excitatory neurotransmission. Cerebrovasc Brain Metab Rev 1990;2(1):27–57.
    • (1990) Cerebrovasc Brain Metab Rev , vol.2 , Issue.1 , pp. 27-57
    • Meldrum, B.1
  • 104
    • 0037320279 scopus 로고    scopus 로고
    • Calcium influx constitutes the ionic basis for the maintenance of glutamate-induced extended neuronal depolarization associated with hippocampal neuronal death
    • Limbrick DD, Jr., Sombati S, DeLorenzo RJ. Calcium influx constitutes the ionic basis for the maintenance of glutamate-induced extended neuronal depolarization associated with hippocampal neuronal death. Cell Calcium 2003;33(2):69–81.
    • (2003) Cell Calcium , vol.33 , Issue.2 , pp. 69-81
    • Limbrick, D.D.1    Sombati, S.2    Delorenzo, R.J.3
  • 105
    • 0034121745 scopus 로고    scopus 로고
    • How botulinum and tetanus neurotoxins block neurotransmitter release
    • Humeau Y, Doussau F, Grant NJ, Poulain B. How botulinum and tetanus neurotoxins block neurotransmitter release. Biochimie 2000;82(5):427–46.
    • (2000) Biochimie , vol.82 , Issue.5 , pp. 427-446
    • Humeau, Y.1    Doussau, F.2    Grant, N.J.3    Poulain, B.4
  • 106
    • 0031909675 scopus 로고    scopus 로고
    • dl-Threo-beta-benzyloxyaspartate, a potent blocker of excitatory amino acid transporters
    • Shimamoto K, Lebrun B, Yasuda-Kamatani Y, et al. dl-Threo-beta-benzyloxyaspartate, a potent blocker of excitatory amino acid transporters. Mol Pharmacol 1998;53(2):195–201.
    • (1998) Mol Pharmacol , vol.53 , Issue.2 , pp. 195-201
    • Shimamoto, K.1    Lebrun, B.2    Yasuda-Kamatani, Y.3
  • 107
    • 1642355796 scopus 로고    scopus 로고
    • Vesicular glutamate transporter-dependent glutamate release from astrocytes
    • Montana V, Ni Y, Sunjara V, Hua X, Parpura V. Vesicular glutamate transporter-dependent glutamate release from astrocytes. J Neurosci 2004;24(11):2633–42.
    • (2004) J Neurosci , vol.24 , Issue.11 , pp. 2633-2642
    • Montana, V.1    Ni, Y.2    Sunjara, V.3    Hua, X.4    Parpura, V.5
  • 108
    • 2542501505 scopus 로고    scopus 로고
    • Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate
    • Bezzi P, Gundersen V, Galbete JL, et al. Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate. Nat Neurosci 2004;7(6):613–20.
    • (2004) Nat Neurosci , vol.7 , Issue.6 , pp. 613-620
    • Bezzi, P.1    Gundersen, V.2    Galbete, J.L.3
  • 112
    • 34548636072 scopus 로고    scopus 로고
    • PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors
    • Cui H, Hayashi A, Sun H-S, et al. PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors. J Neurosci 2007;27(37): 9901–15.
    • (2007) J Neurosci , vol.27 , Issue.37 , pp. 9901-9915
    • Cui, H.1    Hayashi, A.2    Sun, H.-S.3
  • 114
    • 0029927787 scopus 로고    scopus 로고
    • Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice
    • Dawson V, Kizushi V, Huang P, Snyder S, Dawson T. Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice. J Neurosci 1996;16(8):2479–87.
    • (1996) J Neurosci , vol.16 , Issue.8 , pp. 2479-2487
    • Dawson, V.1    Kizushi, V.2    Huang, P.3    Snyder, S.4    Dawson, T.5
  • 115
    • 0027942138 scopus 로고
    • The NOS inhibitor, 7-nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels
    • Yoshida T, Limmroth V, Irikura K, Moskowitz MA. The NOS inhibitor, 7-nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels. J Cereb Blood Flow Metab 1994;14(6):924–9.
    • (1994) J Cereb Blood Flow Metab , vol.14 , Issue.6 , pp. 924-929
    • Yoshida, T.1    Limmroth, V.2    Irikura, K.3    Moskowitz, M.A.4
  • 116
    • 0027945658 scopus 로고
    • Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase
    • Huang Z, Huang PL, Panahian N, Dalkara T, Fishman MC, Moskowitz MA. Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science 1994;265(5180):1883–5.
    • (1994) Science , vol.265 , Issue.5180 , pp. 1883-1885
    • Huang, Z.1    Huang, P.L.2    Panahian, N.3    Dalkara, T.4    Fishman, M.C.5    Moskowitz, M.A.6
  • 117
    • 0027481965 scopus 로고
    • The reaction of NO with superoxide
    • Huie RE, Padmaja S. The reaction of NO with superoxide. Free Radic Res Commun 1993;18(4):195–9.
    • (1993) Free Radic Res Commun , vol.18 , Issue.4 , pp. 195-199
    • Huie, R.E.1    Padmaja, S.2
  • 118
    • 0032911944 scopus 로고    scopus 로고
    • Nitric oxide acutely inhibits neuronal energy production
    • Brorson JR, Schumacker PT, Zhang H. Nitric oxide acutely inhibits neuronal energy production. J Neurosci 1999;19(1):147–58.
    • (1999) J Neurosci , vol.19 , Issue.1 , pp. 147-158
    • Brorson, J.R.1    Schumacker, P.T.2    Zhang, H.3
  • 119
    • 0033120803 scopus 로고    scopus 로고
    • Nitric-oxide-induced apoptosis in human leukemic lines requires mitochondrial lipid degradation and cytochrome c release
    • Ushmorov A, Ratter F, Lehmann V, Droge W, Schirrmacher V, Umansky V. Nitric-oxide-induced apoptosis in human leukemic lines requires mitochondrial lipid degradation and cytochrome c release. Blood 1999;93(7):2342–52.
    • (1999) Blood , vol.93 , Issue.7 , pp. 2342-2352
    • Ushmorov, A.1    Ratter, F.2    Lehmann, V.3    Droge, W.4    Schirrmacher, V.5    Umansky, V.6
  • 120
    • 0030716481 scopus 로고    scopus 로고
    • Kinetics of the inhibition of mitochondrial respiration by NO
    • Koivisto A, Matthias A, Bronnikov G, Nedergaard J. Kinetics of the inhibition of mitochondrial respiration by NO. FEBS Lett 1997;417(1):75–80.
    • (1997) FEBS Lett , vol.417 , Issue.1 , pp. 75-80
    • Koivisto, A.1    Matthias, A.2    Bronnikov, G.3    Nedergaard, J.4
  • 121
    • 0037119624 scopus 로고    scopus 로고
    • S-nitrosylation of matrix metalloproteinases: Signaling pathway to neuronal cell death
    • Gu Z, Kaul M, Yan B, et al. S-nitrosylation of matrix metalloproteinases: Signaling pathway to neuronal cell death. Science 2002;297(5584):1186–90.
    • (2002) Science , vol.297 , Issue.5584 , pp. 1186-1190
    • Gu, Z.1    Kaul, M.2    Yan, B.3
  • 122
    • 0027230852 scopus 로고
    • Developmental changes of cytosolic and particulate nitric oxide synthase in rat brain
    • Matsumoto T, Pollock JS, Nakane M, Forstermann U. Developmental changes of cytosolic and particulate nitric oxide synthase in rat brain. Brain Res Dev Brain Res 1993;73(2): 199–203.
    • (1993) Brain Res Dev Brain Res , vol.73 , Issue.2 , pp. 199-203
    • Matsumoto, T.1    Pollock, J.S.2    Nakane, M.3    Forstermann, U.4
  • 123
    • 0032853974 scopus 로고    scopus 로고
    • Ontogeny of nitric oxide synthase I and III protein expression and enzymatic activity in the guinea pig hippocampus
    • Kimura KA, Reynolds JN, Brien JF. Ontogeny of nitric oxide synthase I and III protein expression and enzymatic activity in the guinea pig hippocampus. Dev Brain Res 1999;116(2): 211–16.
    • (1999) Dev Brain Res , vol.116 , Issue.2 , pp. 211-216
    • Kimura, K.A.1    Reynolds, J.N.2    Brien, J.F.3
  • 124
    • 0035968045 scopus 로고    scopus 로고
    • Ontogenesis of neurons immunoreactive for nitric oxide synthase in rat forebrain and midbrain
    • Terada H, Nagai T, Okada S, Kimura H, Kitahama K. Ontogenesis of neurons immunoreactive for nitric oxide synthase in rat forebrain and midbrain. Dev Brain Res 2001;128(2):121–37.
    • (2001) Dev Brain Res , vol.128 , Issue.2 , pp. 121-137
    • Terada, H.1    Nagai, T.2    Okada, S.3    Kimura, H.4    Kitahama, K.5
  • 125
    • 0030298570 scopus 로고    scopus 로고
    • Patterns of nitric oxide synthase at the messenger RNA and protein levels during early rat brain development
    • Keilhoff G, Seidel B, Noack H, Tischmeyer W, Stanek D, Wolf G. Patterns of nitric oxide synthase at the messenger RNA and protein levels during early rat brain development. Neuroscience 1996;75(4):1193–201.
    • (1996) Neuroscience , vol.75 , Issue.4 , pp. 1193-1201
    • Keilhoff, G.1    Seidel, B.2    Noack, H.3    Tischmeyer, W.4    Stanek, D.5    Wolf, G.6
  • 126
    • 0030697859 scopus 로고    scopus 로고
    • Nitric oxide synthase activity in mitochondria
    • Ghafourifar P, Richter C. Nitric oxide synthase activity in mitochondria. FEBS Lett 1997; 418(3):291–6.
    • (1997) FEBS Lett , vol.418 , Issue.3 , pp. 291-296
    • Ghafourifar, P.1    Richter, C.2
  • 127
    • 0035893981 scopus 로고    scopus 로고
    • Mitochondrial nitric oxide synthase is constitutively active and is functionally upregulated in hypoxia
    • Lacza Z, Puskar M, Figueroa JP, Zhang J, Rajapakse N, Busija DW. Mitochondrial nitric oxide synthase is constitutively active and is functionally upregulated in hypoxia. Free Radic Biol Med 2001;31(12):1609–15.
    • (2001) Free Radic Biol Med , vol.31 , Issue.12 , pp. 1609-1615
    • Lacza, Z.1    Puskar, M.2    Figueroa, J.P.3    Zhang, J.4    Rajapakse, N.5    Busija, D.W.6
  • 129
    • 0037441389 scopus 로고    scopus 로고
    • Characterization and function of mitochondrial nitric-oxide synthase
    • Giulivi C. Characterization and function of mitochondrial nitric-oxide synthase. Free Radic Biol Med 2003;34(4):397–408.
    • (2003) Free Radic Biol Med , vol.34 , Issue.4 , pp. 397-408
    • Giulivi, C.1
  • 130
    • 0035923615 scopus 로고    scopus 로고
    • Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection
    • Kanai AJ, Pearce LL, Clemens PR, et al. Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection. Proc Natl Acad Sci 2001; 98(24):14126–31.
    • (2001) Proc Natl Acad Sci , vol.98 , Issue.24 , pp. 14126-14131
    • Kanai, A.J.1    Pearce, L.L.2    Clemens, P.R.3
  • 131
    • 0037064058 scopus 로고    scopus 로고
    • Biochemistry of mitochondrial nitric-oxide synthase
    • Elfering SL, Sarkela TM, Giulivi C. Biochemistry of mitochondrial nitric-oxide synthase. J Biol Chem 2002;277(41):38079–86.
    • (2002) J Biol Chem , vol.277 , Issue.41 , pp. 38079-38086
    • Elfering, S.L.1    Sarkela, T.M.2    Giulivi, C.3
  • 132
    • 0242352419 scopus 로고    scopus 로고
    • Mitochondrial nitric oxide synthase is not eNOS, nNOS or iNOS
    • Lacza Z, Snipes JA, Zhang J, et al. Mitochondrial nitric oxide synthase is not eNOS, nNOS or iNOS. Free Radic Biol Med 2003;35(10):1217–28.
    • (2003) Free Radic Biol Med , vol.35 , Issue.10 , pp. 1217-1228
    • Lacza, Z.1    Snipes, J.A.2    Zhang, J.3
  • 133
    • 4143099141 scopus 로고    scopus 로고
    • Lack of mitochondrial nitric oxide production in the mouse brain
    • Lacza Z, Horn TF, Snipes JA, et al. Lack of mitochondrial nitric oxide production in the mouse brain. J Neurochem 2004;90(4):942–51.
    • (2004) J Neurochem , vol.90 , Issue.4 , pp. 942-951
    • Lacza, Z.1    Horn, T.F.2    Snipes, J.A.3
  • 134
    • 11144356896 scopus 로고    scopus 로고
    • Docking of eNOS to the mitochondrial outer membrane: A pentabasic amino acid sequence in the autoinhibitory domain of eNOS targets a proteinase K-cleavable peptide on the cytoplasmic face of mitochondria
    • Gao S, Chen J, Brodsky SV, et al. Docking of eNOS to the mitochondrial outer membrane: A pentabasic amino acid sequence in the autoinhibitory domain of eNOS targets a proteinase K-cleavable peptide on the cytoplasmic face of mitochondria. J Biol Chem 2004;279: 15968–74.
    • (2004) J Biol Chem , vol.279 , pp. 15968-15974
    • Gao, S.1    Chen, J.2    Brodsky, S.V.3
  • 135
    • 37149028249 scopus 로고    scopus 로고
    • Interaction of cyanide and nitric oxide with cytochrome c oxidase: Implications for acute cyanide toxicity
    • Leavesley HB, Li L, Prabhakaran K, Borowitz JL, Isom GE. Interaction of cyanide and nitric oxide with cytochrome c oxidase: Implications for acute cyanide toxicity. Toxicol Sci 2008;101(1):101–11.
    • (2008) Toxicol Sci , vol.101 , Issue.1 , pp. 101-111
    • Leavesley, H.B.1    Li, L.2    Prabhakaran, K.3    Borowitz, J.L.4    Isom, G.E.5
  • 136
    • 37749030478 scopus 로고    scopus 로고
    • Hypoxia induces complex I inhibition and ultrastructural damage by increasing mitochondrial nitric oxide in developing CNS
    • Giusti S, Converso DP, Poderoso JJ, Fiszer de Plazas S. Hypoxia induces complex I inhibition and ultrastructural damage by increasing mitochondrial nitric oxide in developing CNS. Eur J Neurosci 2008;27(1):123–31.
    • (2008) Eur J Neurosci , vol.27 , Issue.1 , pp. 123-131
    • Giusti, S.1    Converso, D.P.2    Poderoso, J.J.3    Fiszer de Plazas, S.4
  • 137
    • 33845327490 scopus 로고    scopus 로고
    • Nitric oxide regulation of mitochondrial oxygen consumption I: Cellular physiology
    • Giulivi C, Kato K, Cooper CE. Nitric oxide regulation of mitochondrial oxygen consumption I: Cellular physiology. Am J Physiol Cell Physiol 2006;291(6):C1225–C1231.
    • (2006) Am J Physiol Cell Physiol , vol.291 , Issue.6 , pp. C1225-C1231
    • Giulivi, C.1    Kato, K.2    Cooper, C.E.3
  • 138
    • 20644435792 scopus 로고    scopus 로고
    • Mitochondrial type I nitric oxide synthase physically interacts with cytochrome c oxidase
    • Persichini T, Mazzone V, Polticelli F, et al. Mitochondrial type I nitric oxide synthase physically interacts with cytochrome c oxidase. Neurosci Lett 2005;384:254–9.
    • (2005) Neurosci Lett , vol.384 , pp. 254-259
    • Persichini, T.1    Mazzone, V.2    Polticelli, F.3
  • 139
    • 22044452420 scopus 로고    scopus 로고
    • Hippocampal mitochondrial dysfunction with decreased mtNOS activity in prehepatic portal hypertensive rats
    • Lores-Arnaiz S, Perazzo JC, Prestifilippo JP, et al. Hippocampal mitochondrial dysfunction with decreased mtNOS activity in prehepatic portal hypertensive rats. Neurochem Int 2005;47(5):362–8.
    • (2005) Neurochem Int , vol.47 , Issue.5 , pp. 362-368
    • Lores-Arnaiz, S.1    Perazzo, J.C.2    Prestifilippo, J.P.3
  • 141
    • 3542996356 scopus 로고    scopus 로고
    • Role of calcium signaling in the activation of mitochondrial nitric oxide synthase and citric acid cycle
    • Traaseth N, Elfering S, Solien J, Haynes V, Giulivi C. Role of calcium signaling in the activation of mitochondrial nitric oxide synthase and citric acid cycle. Biochim Biophys Acta (BBA) Bioenergetics 2004;1658(1–2):64–71.
    • (2004) Biochim Biophys Acta (BBA) Bioenergetics , vol.1658 , Issue.1-2 , pp. 64-71
    • Traaseth, N.1    Elfering, S.2    Solien, J.3    Haynes, V.4    Giulivi, C.5
  • 143
    • 0742323115 scopus 로고    scopus 로고
    • Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells
    • Dedkova EN, Ji X, Lipsius SL, Blatter LA. Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells. Am J Physiol Cell Physiol 2003;286(2):C406–C415.
    • (2003) Am J Physiol Cell Physiol , vol.286 , Issue.2 , pp. C406-C415
    • Dedkova, E.N.1    Ji, X.2    Lipsius, S.L.3    Blatter, L.A.4
  • 146
    • 0037044724 scopus 로고    scopus 로고
    • The modulation of mitochondrial nitric-oxide synthase activity in rat brain development
    • Riobo NA, Melani M, Sanjuan N, et al. The modulation of mitochondrial nitric-oxide synthase activity in rat brain development. J Biol Chem 2002;277(45):42447–55.
    • (2002) J Biol Chem , vol.277 , Issue.45 , pp. 42447-42455
    • Riobo, N.A.1    Melani, M.2    Sanjuan, N.3
  • 147
    • 0035831466 scopus 로고    scopus 로고
    • The modulation of oxygen radical production by nitric oxide in mitochondria
    • Sarkela TM, Berthiaume J, Elfering S, Gybina AA, Giulivi C. The modulation of oxygen radical production by nitric oxide in mitochondria. J Biol Chem 2001;276(10):6945–9.
    • (2001) J Biol Chem , vol.276 , Issue.10 , pp. 6945-6949
    • Sarkela, T.M.1    Berthiaume, J.2    Elfering, S.3    Gybina, A.A.4    Giulivi, C.5
  • 148
    • 0034891750 scopus 로고    scopus 로고
    • Subcellular localization of neuronal nitric oxide synthase in the superficial gray layer of the rat superior colliculus
    • Batista CMC, de Paula KC, Cavalcante LA, Mendez-Otero R. Subcellular localization of neuronal nitric oxide synthase in the superficial gray layer of the rat superior colliculus. Neurosci Res 2001;41(1):67–70.
    • (2001) Neurosci Res , vol.41 , Issue.1 , pp. 67-70
    • Batista, C.M.C.1    de Paula, K.C.2    Cavalcante, L.A.3    Mendez-Otero, R.4
  • 150
    • 0032562816 scopus 로고    scopus 로고
    • 2+ uptake into mitochondria in vitro and in situ in single cardiac myocytes
    • 2+ uptake into mitochondria in vitro and in situ in single cardiac myocytes. J Biol Chem 1998;273(17):10223–31.
    • (1998) J Biol Chem , vol.273 , Issue.17 , pp. 10223-10231
    • Matlib, M.A.1    Zhou, Z.2    Knight, S.3
  • 151
    • 0035282782 scopus 로고    scopus 로고
    • Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase
    • Brown GC. Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase. Biochim Biophys Acta 2001;1504(1):46–57.
    • (2001) Biochim Biophys Acta , vol.1504 , Issue.1 , pp. 46-57
    • Brown, G.C.1
  • 152
    • 0023872526 scopus 로고
    • Depth profile of local oxygen tension and blood flow in rat cerebral cortex, white matter and hippocampus
    • Feng ZC, Roberts EL, Jr., Sick TJ, Rosenthal M. Depth profile of local oxygen tension and blood flow in rat cerebral cortex, white matter and hippocampus. Brain Res 1988;445(2):280–8.
    • (1988) Brain Res , vol.445 , Issue.2 , pp. 280-288
    • Feng, Z.C.1    Roberts, E.L.2    Sick, T.J.3    Rosenthal, M.4
  • 153
    • 0027335497 scopus 로고
    • 2 changes in cortex and hippocampus of aging gerbil brain
    • 2 changes in cortex and hippocampus of aging gerbil brain. J Appl Physiol 1993;74(4):1723–8.
    • (1993) J Appl Physiol , vol.74 , Issue.4 , pp. 1723-1728
    • Buerk, D.G.1    Nair, P.2


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