메뉴 건너뛰기




Volumn 34, Issue 4-5, 2003, Pages 407-424

Interactions between mitochondrial bioenegetics and cytoplasmic calcium in cultured cerebellar granule cells

Author keywords

Bioenergetics; Cerebellar granule cells; Cytoplasmic calcium; Glutamate; Membrane potential; Mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMPA RECEPTOR; CALCIUM ION; GLUTAMATE RECEPTOR; GLUTAMIC ACID; KAINIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; REACTIVE OXYGEN METABOLITE; CALCIUM; OLIGOMYCIN; PYRUVIC ACID; UNCOUPLING PROTEIN;

EID: 0042035647     PISSN: 01434160     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0143-4160(03)00144-1     Document Type: Article
Times cited : (96)

References (81)
  • 1
    • 0018864653 scopus 로고
    • Energy transduction in intact synaptosomes: Influence of plasma membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ
    • I.D. Scott, D.G. Nicholls, Energy transduction in intact synaptosomes: influence of plasma membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ, Biochem. J. 186 (1980) 21-33.
    • (1980) Biochem. J. , vol.186 , pp. 21-33
    • Scott, I.D.1    Nicholls, D.G.2
  • 2
    • 0021987016 scopus 로고
    • Calcium efflux and cycling across the synaptosomal plasma membrane
    • R.M. Snelling, D.G. Nicholls, Calcium efflux and cycling across the synaptosomal plasma membrane, Biochem. J. 226 (1985) 225-231.
    • (1985) Biochem. J. , vol.226 , pp. 225-231
    • Snelling, R.M.1    Nicholls, D.G.2
  • 4
    • 0019324973 scopus 로고
    • The regulation of brain mitochondrial calcium-ion transport: The role of ATP in the discrimination between kinetic and membrane-potential-dependent Ca efflux mechanisms
    • D.G. Nicholls, I.D. Scott, The regulation of brain mitochondrial calcium-ion transport: the role of ATP in the discrimination between kinetic and membrane-potential-dependent Ca efflux mechanisms, Biochem. J. 186 (1980) 833-839.
    • (1980) Biochem. J. , vol.186 , pp. 833-839
    • Nicholls, D.G.1    Scott, I.D.2
  • 5
    • 0028137817 scopus 로고
    • Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons
    • J.L. Werth, S.A. Thayer, Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons, J. Neurosci. 14 (1994) 346-356.
    • (1994) J. Neurosci. , vol.14 , pp. 346-356
    • Werth, J.L.1    Thayer, S.A.2
  • 6
    • 0000434165 scopus 로고    scopus 로고
    • 2+ loads by mitochondria in cultured rat hippocampal neurons
    • 2+ loads by mitochondria in cultured rat hippocampal neurons, J. Neurophysiol. 76 (1996) 1611-1621.
    • (1996) J. Neurophysiol. , vol.76 , pp. 1611-1621
    • Wang, G.J.1    Thayer, S.A.2
  • 7
    • 0010297325 scopus 로고
    • Physiological and bioenergetic aspects of mitochondrial Ca transport
    • K.E.O. Åkerman, D.G. Nicholls, Physiological and bioenergetic aspects of mitochondrial Ca transport, Rev. Physiol. Biochem. Pharmacol. 95 (1983) 149-201.
    • (1983) Rev. Physiol. Biochem. Pharmacol. , vol.95 , pp. 149-201
    • Åkerman, K.E.O.1    Nicholls, D.G.2
  • 8
    • 0025331705 scopus 로고
    • Regulation of the intracellular free calcium concentration in single rat dorsal root ganglion neurones in vitro
    • S.A. Thayer, R.J. Miller, Regulation of the intracellular free calcium concentration in single rat dorsal root ganglion neurones in vitro, J. Physiol. (Lond.) 425 (1990) 85-115.
    • (1990) J. Physiol. (Lond.) , vol.425 , pp. 85-115
    • Thayer, S.A.1    Miller, R.J.2
  • 9
    • 0034307759 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells
    • M.W. Ward, A.C. Rego, B.G. Frenguelli, D.G. Nicholls, Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells, J. Neurosci. 20 (2000) 7208-7219.
    • (2000) J. Neurosci. , vol.20 , pp. 7208-7219
    • Ward, M.W.1    Rego, A.C.2    Frenguelli, B.G.3    Nicholls, D.G.4
  • 10
    • 0028097733 scopus 로고
    • The quantity of calcium that appears to induce neuronal death
    • S. Eimerl, M. Schramm, The quantity of calcium that appears to induce neuronal death, J. Neurochem. 62 (1994) 1223-1226.
    • (1994) J. Neurochem. , vol.62 , pp. 1223-1226
    • Eimerl, S.1    Schramm, M.2
  • 11
    • 0033105949 scopus 로고    scopus 로고
    • High-affinity calcium indicators underestimate increases in intracellular calcium concentrations associated with excitotoxic glutamate stimulations
    • A.K. Stout, I.J. Reynolds, High-affinity calcium indicators underestimate increases in intracellular calcium concentrations associated with excitotoxic glutamate stimulations, Neuroscience 89 (1999) 91-100.
    • (1999) Neuroscience , vol.89 , pp. 91-100
    • Stout, A.K.1    Reynolds, I.J.2
  • 12
    • 0030071252 scopus 로고    scopus 로고
    • A re-evaluation of the role of mitochondria in neuronal calcium homeostasis
    • S.L. Budd, D.G. Nicholls, A re-evaluation of the role of mitochondria in neuronal calcium homeostasis, J. Neurochem. 66 (1996) 403-411.
    • (1996) J. Neurochem. , vol.66 , pp. 403-411
    • Budd, S.L.1    Nicholls, D.G.2
  • 13
    • 0029827804 scopus 로고    scopus 로고
    • Mitochondrial calcium regulation and acute glutamate excitotoxicity in cultured cerebellar granule cells
    • S.L. Budd, D.G. Nicholls, Mitochondrial calcium regulation and acute glutamate excitotoxicity in cultured cerebellar granule cells, J. Neurochem. 67 (1996) 2282-2291.
    • (1996) J. Neurochem. , vol.67 , pp. 2282-2291
    • Budd, S.L.1    Nicholls, D.G.2
  • 14
    • 0032535275 scopus 로고    scopus 로고
    • Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells
    • R.F. Castilho, O. Hansson, M.W. Ward, S.L. Budd, D.G. Nicholls, Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells, J. Neurosci. 18 (1998) 10277-10286.
    • (1998) J. Neurosci. , vol.18 , pp. 10277-10286
    • Castilho, R.F.1    Hansson, O.2    Ward, M.W.3    Budd, S.L.4    Nicholls, D.G.5
  • 15
    • 0027461218 scopus 로고
    • Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium
    • P. Legendre, C. Rosenmund, G.L. Westbrook, Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium, J. Neurosci. 13 (1993) 674-684.
    • (1993) J. Neurosci. , vol.13 , pp. 674-684
    • Legendre, P.1    Rosenmund, C.2    Westbrook, G.L.3
  • 16
    • 0033179293 scopus 로고    scopus 로고
    • Depolarization-induced mitochondrial Ca accumulation in sympathetic neurons: Spatial and temporal characteristics
    • N.B. Pivovarova, J. Hongpaisan, S.B. Andrews, D.D. Friel, Depolarization-induced mitochondrial Ca accumulation in sympathetic neurons: spatial and temporal characteristics, J. Neurosci. 19 (1999) 6372-6384.
    • (1999) J. Neurosci. , vol.19 , pp. 6372-6384
    • Pivovarova, N.B.1    Hongpaisan, J.2    Andrews, S.B.3    Friel, D.D.4
  • 17
    • 0035901525 scopus 로고    scopus 로고
    • Perinuclear, perigranular and sub-plasmalemmal mitochondria have distinct functions in the regulation of cellular calcium transport
    • M.K. Park, M.C. Ashby, G. Erdemli, O.H. Petersen, A.V. Tepikin, Perinuclear, perigranular and sub-plasmalemmal mitochondria have distinct functions in the regulation of cellular calcium transport, EMBO J. 20 (2001) 1863-1874.
    • (2001) EMBO J. , vol.20 , pp. 1863-1874
    • Park, M.K.1    Ashby, M.C.2    Erdemli, G.3    Petersen, O.H.4    Tepikin, A.V.5
  • 18
    • 0033840949 scopus 로고    scopus 로고
    • Lactate prevents the alterations in tissue amino acids decline in ATP and cell damage due to aglycemia in retina
    • G.D. Zeevalk, W.J. Nicklas, Lactate prevents the alterations in tissue amino acids decline in ATP and cell damage due to aglycemia in retina, J. Neurochem. 75 (2000) 1027-1034.
    • (2000) J. Neurochem. , vol.75 , pp. 1027-1034
    • Zeevalk, G.D.1    Nicklas, W.J.2
  • 19
    • 0032850167 scopus 로고    scopus 로고
    • Pyruvate and lactate protect striatal neurons against N-methyl-D-aspartate-induced neurotoxicity
    • M. Maus, P. Marin, M. Israël, J. Glowinski, J. Prémont, Pyruvate and lactate protect striatal neurons against N-methyl-D-aspartate-induced neurotoxicity, Eur. J. Neurosci. 11 (1999) 3215-3224.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 3215-3224
    • Maus, M.1    Marin, P.2    Israël, M.3    Glowinski, J.4    Prémont, J.5
  • 20
    • 0032929864 scopus 로고    scopus 로고
    • An increase in lactate output by brain tissue serves to meet the energy demands of glutamate-activated neurons
    • A. Schurr, J.J. Miller, R.S. Payne, B.M. Rigor, An increase in lactate output by brain tissue serves to meet the energy demands of glutamate-activated neurons, J. Neurosci. 19 (1999) 34-39.
    • (1999) J. Neurosci. , vol.19 , pp. 34-39
    • Schurr, A.1    Miller, J.J.2    Payne, R.S.3    Rigor, B.M.4
  • 21
    • 0032507589 scopus 로고    scopus 로고
    • Protection by pyruvate and malate against glutamate-mediated neurotoxicity
    • F. Ruiz, G. Alvarez, R. Pereira, et al., Protection by pyruvate and malate against glutamate-mediated neurotoxicity, NeuroReport 9 (1998) 1277-1282.
    • (1998) NeuroReport , vol.9 , pp. 1277-1282
    • Ruiz, F.1    Alvarez, G.2    Pereira, R.3
  • 22
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • P. Lipton, Ischemic cell death in brain neurons, Physiol. Rev. 79 (1999) 1431-1568.
    • (1999) Physiol. Rev. , vol.79 , pp. 1431-1568
    • Lipton, P.1
  • 23
    • 0014668762 scopus 로고
    • Brain lesions, obesity and other disturbances in mice treated with monosodium glutamate
    • J.W. Olney, Brain lesions, obesity and other disturbances in mice treated with monosodium glutamate, Science 164 (1969) 719-721.
    • (1969) Science , vol.164 , pp. 719-721
    • Olney, J.W.1
  • 24
    • 0026608995 scopus 로고
    • Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons
    • R.D. Randall, S.A. Thayer, Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons, J. Neurosci. 12 (1992) 1882-1895.
    • (1992) J. Neurosci. , vol.12 , pp. 1882-1895
    • Randall, R.D.1    Thayer, S.A.2
  • 25
    • 0027339920 scopus 로고
    • 2+ overload indicates early neuronal injury which precedes staining with viability indicators
    • 2+ overload indicates early neuronal injury which precedes staining with viability indicators, Brain Res. 607 (1993) 319-323.
    • (1993) Brain Res. , vol.607 , pp. 319-323
    • Tymianski, M.1    Charlton, M.P.2    Carlen, P.L.3    Tator, C.H.4
  • 26
    • 0035869336 scopus 로고    scopus 로고
    • Mitochondria control AMPA/kainate receptor-induced cytoplasmic calcium deregulation in rat cerebellar granule cells
    • A.C. Rego, M.W. Ward, D.G. Nicholls, Mitochondria control AMPA/kainate receptor-induced cytoplasmic calcium deregulation in rat cerebellar granule cells, J. Neurosci. 21 (2001) 1893-1901.
    • (2001) J. Neurosci. , vol.21 , pp. 1893-1901
    • Rego, A.C.1    Ward, M.W.2    Nicholls, D.G.3
  • 27
    • 0031792791 scopus 로고    scopus 로고
    • Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity
    • R. Sattler, M.P. Charlton, M. Hafner, M. Tymianski, Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity, J. Neurochem. 71 (1998) 2349-2364.
    • (1998) J. Neurochem. , vol.71 , pp. 2349-2364
    • Sattler, R.1    Charlton, M.P.2    Hafner, M.3    Tymianski, M.4
  • 28
    • 0036024018 scopus 로고    scopus 로고
    • Cleavage of plasma membrane calcium pumps by caspases: A link between apoptosis and necrosis
    • B.L. Schwab, D. Guerini, C. Didszun, et al., Cleavage of plasma membrane calcium pumps by caspases: a link between apoptosis and necrosis, Cell Death Differ. 9 (2002) 818-831.
    • (2002) Cell Death Differ. , vol.9 , pp. 818-831
    • Schwab, B.L.1    Guerini, D.2    Didszun, C.3
  • 29
    • 0035831137 scopus 로고    scopus 로고
    • 2+ sequestration/extrusion mechanisms following excitotoxic glutamate exposure
    • 2+ sequestration/extrusion mechanisms following excitotoxic glutamate exposure, Brain Res. 894 (2001) 56-67.
    • (2001) Brain Res. , vol.894 , pp. 56-67
    • Limbrick, D.D.1    Pal, S.2    DeLorenzo, R.J.3
  • 32
    • 0035066857 scopus 로고    scopus 로고
    • Oxidatively modified calmodulin binds to the plasma membrane Ca-ATPase in a nonproductive and conformationally disordered complex
    • J. Gao, Y.H. Yao, T.C. Squier, Oxidatively modified calmodulin binds to the plasma membrane Ca-ATPase in a nonproductive and conformationally disordered complex, Biophys. J. 80 (2001) 1791-1801.
    • (2001) Biophys. J. , vol.80 , pp. 1791-1801
    • Gao, J.1    Yao, Y.H.2    Squier, T.C.3
  • 33
    • 0033524399 scopus 로고    scopus 로고
    • Repair of oxidized calmodulin by methionine sulfoxide reductase restores ability to activate the plasma membrane Ca-ATPase
    • H. Sun, J. Gao, D.A. Ferrington, H. Biesiada, T.D. Williams, T.C. Squier, Repair of oxidized calmodulin by methionine sulfoxide reductase restores ability to activate the plasma membrane Ca-ATPase, Biochemistry 38 (1999) 105-112.
    • (1999) Biochemistry , vol.38 , pp. 105-112
    • Sun, H.1    Gao, J.2    Ferrington, D.A.3    Biesiada, H.4    Williams, T.D.5    Squier, T.C.6
  • 34
    • 0033199019 scopus 로고    scopus 로고
    • Glutamate-induced mitochondrial depolarization and perturbation of calcium homeostasis in cultured rat hippocampal neurones
    • O. Vergun, J. Keelan, B.I. Khodorov, M.R. Duchen, Glutamate-induced mitochondrial depolarization and perturbation of calcium homeostasis in cultured rat hippocampal neurones, J. Physiol. (Lond.) 519 (1999) 451-466.
    • (1999) J. Physiol. (Lond.) , vol.519 , pp. 451-466
    • Vergun, O.1    Keelan, J.2    Khodorov, B.I.3    Duchen, M.R.4
  • 35
    • 0034535252 scopus 로고    scopus 로고
    • Quantitative biochemical and ultrastructural comparison of mitochondrial permeability transition in isolated brain and liver mitochondria: Evidence for reduced sensitivity of brain mitochondria
    • S.B. Berman, S.C. Watkins, T.G. Hastings, Quantitative biochemical and ultrastructural comparison of mitochondrial permeability transition in isolated brain and liver mitochondria: evidence for reduced sensitivity of brain mitochondria, Exp. Neurol. 164 (2000) 415-425.
    • (2000) Exp. Neurol. , vol.164 , pp. 415-425
    • Berman, S.B.1    Watkins, S.C.2    Hastings, T.G.3
  • 36
    • 0034668844 scopus 로고    scopus 로고
    • Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria
    • N. Brustovetsky, J.M. Dubinsky, Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria, J. Neurosci. 20 (2000) 8229-8237.
    • (2000) J. Neurosci. , vol.20 , pp. 8229-8237
    • Brustovetsky, N.1    Dubinsky, J.M.2
  • 37
    • 0031912196 scopus 로고    scopus 로고
    • N-Methyl-D-aspartate receptor desensitisation is neuroprotective by inhibiting glutamate-induced apoptotic-like death
    • A.M. Wood, D.R. Bristow, N-Methyl-D-aspartate receptor desensitisation is neuroprotective by inhibiting glutamate-induced apoptotic-like death, J. Neurochem. 70 (1998) 677-687.
    • (1998) J. Neurochem. , vol.70 , pp. 677-687
    • Wood, A.M.1    Bristow, D.R.2
  • 38
    • 0028236667 scopus 로고
    • 2+-dependent phosphatase
    • 2+-dependent phosphatase, Nature 369 (1994) 235-239.
    • (1994) Nature , vol.369 , pp. 235-239
    • Lieberman, D.N.1    Mody, I.2
  • 39
    • 0027965033 scopus 로고
    • Regulation of glycine-insensitive desensitization of the NMDA receptor in outside-out patches
    • G. Tong, C.E. Jahr, Regulation of glycine-insensitive desensitization of the NMDA receptor in outside-out patches, J. Neurophysiol. 72 (1994) 754-761.
    • (1994) J. Neurophysiol. , vol.72 , pp. 754-761
    • Tong, G.1    Jahr, C.E.2
  • 40
    • 0028929331 scopus 로고
    • Synaptic desensitization of NMDA receptors by calcineurin
    • G. Tong, D. Shepherd, C.E. Jahr, Synaptic desensitization of NMDA receptors by calcineurin, Science 267 (1995) 1510-1512.
    • (1995) Science , vol.267 , pp. 1510-1512
    • Tong, G.1    Shepherd, D.2    Jahr, C.E.3
  • 41
    • 0036236357 scopus 로고    scopus 로고
    • Calcineurin acts via the C-terminus of NR2A to modulate desensitization of NMDA receptors
    • J.J. Krupp, B. Vissel, C.G. Thomas, S.F. Heinemann, G.L. Westbrook, Calcineurin acts via the C-terminus of NR2A to modulate desensitization of NMDA receptors, Neuropharmacology 42 (2002) 593-602.
    • (2002) Neuropharmacology , vol.42 , pp. 593-602
    • Krupp, J.J.1    Vissel, B.2    Thomas, C.G.3    Heinemann, S.F.4    Westbrook, G.L.5
  • 42
    • 0029810095 scopus 로고    scopus 로고
    • Mitochondrial dysfunction is a primary event in glutamate excitotoxicity
    • A.F. Schinder, E.C. Olson, N.C. Spitzer, M. Montal, Mitochondrial dysfunction is a primary event in glutamate excitotoxicity, J. Neurosci. 16 (1996) 6125-6133.
    • (1996) J. Neurosci. , vol.16 , pp. 6125-6133
    • Schinder, A.F.1    Olson, E.C.2    Spitzer, N.C.3    Montal, M.4
  • 43
    • 0030298459 scopus 로고    scopus 로고
    • Cyclosporin a delays mitochondrial depolarization induced by N-methyl-D-aspaparte in cortical neurons: Evidence of the mitochondrial permeability transition
    • A.L. Nieminen, T.G. Petrie, J.J. Lemasters, W.R. Selman, Cyclosporin a delays mitochondrial depolarization induced by N-methyl-D-aspaparte in cortical neurons: evidence of the mitochondrial permeability transition, Neuroscience 75 (1996) 993-997.
    • (1996) Neuroscience , vol.75 , pp. 993-997
    • Nieminen, A.L.1    Petrie, T.G.2    Lemasters, J.J.3    Selman, W.R.4
  • 44
    • 0032530326 scopus 로고    scopus 로고
    • Calcium-induced activation of the mitochondrial permeability transition in hippocampal neurons
    • J.M. Dubinsky, Y. Levi, Calcium-induced activation of the mitochondrial permeability transition in hippocampal neurons, J. Neurosci. Res. 53 (1998) 728-741.
    • (1998) J. Neurosci. Res. , vol.53 , pp. 728-741
    • Dubinsky, J.M.1    Levi, Y.2
  • 45
    • 0027240533 scopus 로고
    • Macrolide antibiotics protect neurons in culture against the N-methyl-D-aspartate (NMDA) receptor-mediated toxicity of glutamate
    • H. Manev, M. Favaron, P. Candeo, E. Fadda, M. Lipartiti, D. Milani, Macrolide antibiotics protect neurons in culture against the N-methyl-D-aspartate (NMDA) receptor-mediated toxicity of glutamate, Brain Res. 624 (1993) 331-335.
    • (1993) Brain Res. , vol.624 , pp. 331-335
    • Manev, H.1    Favaron, M.2    Candeo, P.3    Fadda, E.4    Lipartiti, M.5    Milani, D.6
  • 46
    • 0030574021 scopus 로고    scopus 로고
    • Calcineurin and mitochondrial function in glutamate-induced neuronal cell death
    • M. Ankarcrona, J.M. Dypbukt, S. Orrenius, P. Nicotera, Calcineurin and mitochondrial function in glutamate-induced neuronal cell death, FEBS Lett. 394 (1996) 321-324.
    • (1996) FEBS Lett. , vol.394 , pp. 321-324
    • Ankarcrona, M.1    Dypbukt, J.M.2    Orrenius, S.3    Nicotera, P.4
  • 47
    • 0032860116 scopus 로고    scopus 로고
    • Cyclosporin A and its non-immunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons
    • L. Khaspekov, H. Friberg, A. Halestrap, I. Viktorov, T. Wieloch, Cyclosporin A and its non-immunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons, Eur. J. Neurosci. 11 (1999) 3194-3198.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 3194-3198
    • Khaspekov, L.1    Friberg, H.2    Halestrap, A.3    Viktorov, I.4    Wieloch, T.5
  • 48
    • 0036488223 scopus 로고    scopus 로고
    • Mitochondrial permeability transition and calcium dynamics in striatal neurons upon intense NMDA receptor activation
    • C.C. Alano, G. Beutner, R.T. Dirksen, R.A. Gross, S.S. Shen, Mitochondrial permeability transition and calcium dynamics in striatal neurons upon intense NMDA receptor activation, J. Neurochem. 80 (2002) 531-538.
    • (2002) J. Neurochem. , vol.80 , pp. 531-538
    • Alano, C.C.1    Beutner, G.2    Dirksen, R.T.3    Gross, R.A.4    Shen, S.S.5
  • 49
    • 0034705057 scopus 로고    scopus 로고
    • Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons
    • S.L. Budd, L. Tenneti, T. Lishnak, S.A. Lipton, Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons, Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 6161-6166.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 6161-6166
    • Budd, S.L.1    Tenneti, L.2    Lishnak, T.3    Lipton, S.A.4
  • 50
    • 0033198273 scopus 로고    scopus 로고
    • Mitochondrial depolarization is not required for neuronal apoptosis
    • A.J. Krohn, T. Wahlbrink, J.H.M. Prehn, Mitochondrial depolarization is not required for neuronal apoptosis, J. Neurosci. 19 (1999) 7394-7404.
    • (1999) J. Neurosci. , vol.19 , pp. 7394-7404
    • Krohn, A.J.1    Wahlbrink, T.2    Prehn, J.H.M.3
  • 51
    • 0033042778 scopus 로고    scopus 로고
    • Glutamate neurotoxicity in rat cerebellar granule cells involves cytochrome c release from mitochondria and mitochondrial shuttle impairment
    • A. Atlante, S. Gagliardi, E. Marra, P. Calissano, S. Passarella, Glutamate neurotoxicity in rat cerebellar granule cells involves cytochrome c release from mitochondria and mitochondrial shuttle impairment, J. Neurochem. 73 (1999) 237-246.
    • (1999) J. Neurochem. , vol.73 , pp. 237-246
    • Atlante, A.1    Gagliardi, S.2    Marra, E.3    Calissano, P.4    Passarella, S.5
  • 52
    • 0032833281 scopus 로고    scopus 로고
    • 2+ influx and excitotoxicity
    • 2+ influx and excitotoxicity, Mol. Pharmacol. 56 (1999) 737-743.
    • (1999) Mol. Pharmacol. , vol.56 , pp. 737-743
    • Kiedrowski, L.1
  • 54
    • 0033061920 scopus 로고    scopus 로고
    • Oxidative stress, mitochondrial function and acute glutamate excitotoxicity in cultured cerebellar granule cells
    • R.F. Castilho, M.W. Ward, D.G. Nicholls, Oxidative stress, mitochondrial function and acute glutamate excitotoxicity in cultured cerebellar granule cells, J. Neurochem. 72 (1999) 1394-1401.
    • (1999) J. Neurochem. , vol.72 , pp. 1394-1401
    • Castilho, R.F.1    Ward, M.W.2    Nicholls, D.G.3
  • 55
    • 0035863011 scopus 로고    scopus 로고
    • Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space
    • D. Han, E. Williams, E. Cadenas, Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space, Biochem. J. 353 (2001) 411-416.
    • (2001) Biochem. J. , vol.353 , pp. 411-416
    • Han, D.1    Williams, E.2    Cadenas, E.3
  • 56
    • 0030729851 scopus 로고    scopus 로고
    • High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
    • S.S. Korshunov, V.P. Skulachev, A.A. Starkov, High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria, FEBS Lett. 416 (1997) 15-18.
    • (1997) FEBS Lett. , vol.416 , pp. 15-18
    • Korshunov, S.S.1    Skulachev, V.P.2    Starkov, A.A.3
  • 57
    • 0036788941 scopus 로고    scopus 로고
    • Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax
    • A.A. Starkov, B.M. Polster, G. Fiskum, Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax, J. Neurochem. 83 (2002) 220-228.
    • (2002) J. Neurochem. , vol.83 , pp. 220-228
    • Starkov, A.A.1    Polster, B.M.2    Fiskum, G.3
  • 58
    • 0034816698 scopus 로고    scopus 로고
    • Cytochrome c is a potent catalyst of dichlorofluorescin oxidation: Implications for the role of reactive oxygen species in apoptosis
    • M.J. Burkitt, P. Wardman, Cytochrome c is a potent catalyst of dichlorofluorescin oxidation: Implications for the role of reactive oxygen species in apoptosis, Biochem. Biophys. Res. Commun. 282 (2001) 329-333.
    • (2001) Biochem. Biophys. Res. Commun. , vol.282 , pp. 329-333
    • Burkitt, M.J.1    Wardman, P.2
  • 59
    • 0030761155 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and hydroethidine-monitored superoxide generation in cerebellar granule cells
    • S.L. Budd, R.F. Castilho, D.G. Nicholls, Mitochondrial membrane potential and hydroethidine-monitored superoxide generation in cerebellar granule cells, FEBS Lett. 415 (1997) 21-24.
    • (1997) FEBS Lett. , vol.415 , pp. 21-24
    • Budd, S.L.1    Castilho, R.F.2    Nicholls, D.G.3
  • 62
    • 0034518449 scopus 로고    scopus 로고
    • 2+ in cell physiology and pathophysiology
    • 2+ in cell physiology and pathophysiology, Cell Calcium 28 (2000) 339-348.
    • (2000) Cell Calcium , vol.28 , pp. 339-348
    • Duchen, M.R.1
  • 63
    • 0041196069 scopus 로고    scopus 로고
    • Metalloporphyrin class of therapeutic catalytic antioxidants
    • M. Patel, B.J. Day, Metalloporphyrin class of therapeutic catalytic antioxidants, Trends Pharmacol. Sci. 20 (1999) 359-364.
    • (1999) Trends Pharmacol. Sci. , vol.20 , pp. 359-364
    • Patel, M.1    Day, B.J.2
  • 64
    • 0035865259 scopus 로고    scopus 로고
    • Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture
    • O. Vergun, A.I. Sobolevsky, M.V. Yelshansky, J. Keelan, B.I. Khodorov, M.R. Duchen, Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture, J. Physiol. (Lond.) 531 (2001) 147-163.
    • (2001) J. Physiol. (Lond.) , vol.531 , pp. 147-163
    • Vergun, O.1    Sobolevsky, A.I.2    Yelshansky, M.V.3    Keelan, J.4    Khodorov, B.I.5    Duchen, M.R.6
  • 65
    • 0034254932 scopus 로고    scopus 로고
    • Delayed mitochondrial dysfunction in excitotoxic neuron death: Cytochrome c release and a secondary increase in superoxide production
    • C.M. Luetjens, N.T. Bui, B. Sengpiel, et al., Delayed mitochondrial dysfunction in excitotoxic neuron death: cytochrome c release and a secondary increase in superoxide production, J. Neurosci. 20 (2000) 5715-5723.
    • (2000) J. Neurosci. , vol.20 , pp. 5715-5723
    • Luetjens, C.M.1    Bui, N.T.2    Sengpiel, B.3
  • 66
    • 0035371184 scopus 로고    scopus 로고
    • Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple
    • F.Q. Schafer, G.R. Buettner, Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple, Free Radic. Biol. Med. 30 (2001) 1191-1212.
    • (2001) Free Radic. Biol. Med. , vol.30 , pp. 1191-1212
    • Schafer, F.Q.1    Buettner, G.R.2
  • 67
    • 0017817970 scopus 로고
    • Brown adipose tissue mitochondria: Photoaffinity labelling of the regulatory site for energy dissipation
    • G.M. Heaton, R.J. Wagenvoord, A. Kemp, D.G. Nicholls, Brown adipose tissue mitochondria: photoaffinity labelling of the regulatory site for energy dissipation, Eur. J. Biochem. 82 (1978) 515-521.
    • (1978) Eur. J. Biochem. , vol.82 , pp. 515-521
    • Heaton, G.M.1    Wagenvoord, R.J.2    Kemp, A.3    Nicholls, D.G.4
  • 68
    • 0021322138 scopus 로고
    • Thermogenic mechanisms in brown fat
    • D.G. Nicholls, R.M. Locke, Thermogenic mechanisms in brown fat, Physiol. Rev. 64 (1984) 1-64.
    • (1984) Physiol. Rev. , vol.64 , pp. 1-64
    • Nicholls, D.G.1    Locke, R.M.2
  • 69
    • 0033032999 scopus 로고    scopus 로고
    • Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia
    • 1410
    • A.H.V. Schapira, Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia, Biochim. Biophys. Acta Bio-Energetics 1410 (1999) 159-170.
    • (1999) Biochim. Biophys. Acta Bio-Energetics , pp. 159-170
    • Schapira, A.H.V.1
  • 70
    • 0016304940 scopus 로고
    • Hamster brown adipose tissue mitochondria: The control of respiration and the proton electrochemical potential by possible physiological effectors of the proton conductance of the inner membrane
    • D.G. Nicholls, Hamster brown adipose tissue mitochondria: the control of respiration and the proton electrochemical potential by possible physiological effectors of the proton conductance of the inner membrane, Eur. J. Biochem. 49 (1974) 573-583.
    • (1974) Eur. J. Biochem. , vol.49 , pp. 573-583
    • Nicholls, D.G.1
  • 71
    • 18244379331 scopus 로고    scopus 로고
    • Superoxide activates mitochondrial uncoupling proteins
    • K.S. Echtay, D. Roussel, J. St. Pierre, et al., Superoxide activates mitochondrial uncoupling proteins, Nature 415 (2002) 96-99.
    • (2002) Nature , vol.415 , pp. 96-99
    • Echtay, K.S.1    Roussel, D.2    St. Pierre, J.3
  • 72
    • 0016294206 scopus 로고
    • The influence of respiration and ATP hydrolysis on the proton electrochemical potential gradient across the inner membrane of rat liver mitochondria as determined by ion distribution
    • D.G. Nicholls, The influence of respiration and ATP hydrolysis on the proton electrochemical potential gradient across the inner membrane of rat liver mitochondria as determined by ion distribution, Eur. J. Biochem. 50 (1974) 305-315.
    • (1974) Eur. J. Biochem. , vol.50 , pp. 305-315
    • Nicholls, D.G.1
  • 73
    • 0017638174 scopus 로고
    • The effective proton conductances of the inner membrane of mitochondria from brown adipose tissue: Dependency on proton electrochemical gradient
    • D.G. Nicholls, The effective proton conductances of the inner membrane of mitochondria from brown adipose tissue: dependency on proton electrochemical gradient, Eur. J. Biochem. 77 (1977) 349-356.
    • (1977) Eur. J. Biochem. , vol.77 , pp. 349-356
    • Nicholls, D.G.1
  • 74
    • 0016288209 scopus 로고
    • Acetate: A major end-product of fatty acid oxidation in hamster brown adipose tissue mitochondria
    • V.S.M. Bernson, D.G. Nicholls, Acetate: a major end-product of fatty acid oxidation in hamster brown adipose tissue mitochondria, Eur. J. Biochem. 47 (1974) 517-525.
    • (1974) Eur. J. Biochem. , vol.47 , pp. 517-525
    • Bernson, V.S.M.1    Nicholls, D.G.2
  • 75
    • 0033232538 scopus 로고    scopus 로고
    • 2+ permeation of AMPA receptors in cerebellar neurons expressing Glu receptor 2
    • 2+ permeation of AMPA receptors in cerebellar neurons expressing Glu receptor 2, J. Neurosci. 19 (1999) 9149-9159.
    • (1999) J. Neurosci. , vol.19 , pp. 9149-9159
    • Brorson, J.R.1    Zhang, Z.H.2    Vandenberghe, W.3
  • 76
    • 0028340999 scopus 로고
    • Intracellular sodium concentration in cultured cerebellar granule cells challenged with glutamate
    • L. Kiedrowski, J.T. Wroblewski, E. Costa, Intracellular sodium concentration in cultured cerebellar granule cells challenged with glutamate, Mol. Pharmacol. 45 (1994) 1050-1054.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 1050-1054
    • Kiedrowski, L.1    Wroblewski, J.T.2    Costa, E.3
  • 77
    • 0028256101 scopus 로고
    • Glutamate impairs neuronal calcium extrusion while reducing sodium gradient
    • L. Kiedrowski, G. Brooker, E. Costa, J.T. Wroblewski, Glutamate impairs neuronal calcium extrusion while reducing sodium gradient, Neuron 12 (1994) 295-300.
    • (1994) Neuron , vol.12 , pp. 295-300
    • Kiedrowski, L.1    Brooker, G.2    Costa, E.3    Wroblewski, J.T.4
  • 78
    • 0028842324 scopus 로고
    • Glutamate-induced destabilization of intracellular calcium concentration homeostasis in cultured cerebellar granule cells: Role of mitochondria in calcium buffering
    • L. Kiedrowski, E. Costa, Glutamate-induced destabilization of intracellular calcium concentration homeostasis in cultured cerebellar granule cells: role of mitochondria in calcium buffering, Mol. Pharmacol. 47 (1995) 140-147.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 140-147
    • Kiedrowski, L.1    Costa, E.2
  • 79
    • 0031818025 scopus 로고    scopus 로고
    • The difference between mechanisms of kainate and glutamate excitotoxicity in vitro: Osmotic lesion versus mitochondrial depolarization
    • L. Kiedrowski, The difference between mechanisms of kainate and glutamate excitotoxicity in vitro: osmotic lesion versus mitochondrial depolarization, Restor. Neurol. Neurosci. 12 (1998) 71-79.
    • (1998) Restor. Neurol. Neurosci. , vol.12 , pp. 71-79
    • Kiedrowski, L.1
  • 80
    • 0029075173 scopus 로고
    • Glutamate exocytosis from cerebellar granule cells: The mechanism of a transition to an L-type Ca channel coupling
    • J.M. Pocock, M.A. Cousin, J. Parkin, D.G. Nicholls, Glutamate exocytosis from cerebellar granule cells: the mechanism of a transition to an L-type Ca channel coupling, Neuroscience 67 (1995) 595-607.
    • (1995) Neuroscience , vol.67 , pp. 595-607
    • Pocock, J.M.1    Cousin, M.A.2    Parkin, J.3    Nicholls, D.G.4
  • 81
    • 0017373769 scopus 로고
    • Inter-relationships between proton electrochemical gradient, adenine nucleotide phosphorylation potential and respiration during substrate-level and oxidative phosphorylation by mitochondria from brown adipose tissue of cold-adapted guinea-pigs
    • D.G. Nicholls, V.S.M. Bernson, Inter-relationships between proton electrochemical gradient, adenine nucleotide phosphorylation potential and respiration during substrate-level and oxidative phosphorylation by mitochondria from brown adipose tissue of cold-adapted guinea-pigs, Eur. J. Biochem. 75 (1977) 601-612.
    • (1977) Eur. J. Biochem. , vol.75 , pp. 601-612
    • Nicholls, D.G.1    Bernson, V.S.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.