메뉴 건너뛰기




Volumn 8, Issue 4, 2007, Pages 361-368

Changes of biomarkers with oral exposure to benzo(a)pyrene, phenanthrene and pyrene in rats

Author keywords

Benzo(a)pyrene; Biomarker; PAHs; Phenanthrene; Pyrene

Indexed keywords

RATTUS;

EID: 37349045953     PISSN: 1229845X     EISSN: None     Source Type: Journal    
DOI: 10.4142/jvs.2007.8.4.361     Document Type: Article
Times cited : (18)

References (44)
  • 1
    • 0026482795 scopus 로고
    • An improved fluorometric assay for dosimetry of benzo(a)pyrene diol-epoxide-DNA adducts in smokers' lung: Comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity
    • Alexandrov K, Rojas M, Geneste O, Castegnaro M, Camus AM, Petruzzelli S, Giuntini C, Bartsch H. An improved fluorometric assay for dosimetry of benzo(a)pyrene diol-epoxide-DNA adducts in smokers' lung: comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity. Cancer Res 1992, 52, 6248-6253.
    • (1992) Cancer Res , vol.52 , pp. 6248-6253
    • Alexandrov, K.1    Rojas, M.2    Geneste, O.3    Castegnaro, M.4    Camus, A.M.5    Petruzzelli, S.6    Giuntini, C.7    Bartsch, H.8
  • 2
    • 0029662671 scopus 로고    scopus 로고
    • The effects of near ultraviolet radiation on the toxic effects of polycyclic aromatic hydrocarbons in animals and plants: A review
    • Arfsten DP, Schaeffer DJ, Muneny DC. The effects of near ultraviolet radiation on the toxic effects of polycyclic aromatic hydrocarbons in animals and plants: a review. Ecotoxicol Environ Saf 1996, 33, 1-24.
    • (1996) Ecotoxicol Environ Saf , vol.33 , pp. 1-24
    • Arfsten, D.P.1    Schaeffer, D.J.2    Muneny, D.C.3
  • 3
    • 0032587413 scopus 로고    scopus 로고
    • 32P-Postlabeling analysis of lipophilic DNA adducts resulting from interaction with (±)-3-hydroxy-trans-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydro-benzo[a]pyrene. Chem Biol Interact 1999, 118, 87-97.
    • 32P-Postlabeling analysis of lipophilic DNA adducts resulting from interaction with (±)-3-hydroxy-trans-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydro-benzo[a]pyrene. Chem Biol Interact 1999, 118, 87-97.
  • 4
    • 0036771751 scopus 로고    scopus 로고
    • In vitro EROD induction equivalency factor for the 10 PAHs generally monitored in risk assessment studies in the Netherlands
    • Bosveld ATC, de Bie PAF, van den Brink NW, Jongepier H, Klomp AV. In vitro EROD induction equivalency factor for the 10 PAHs generally monitored in risk assessment studies in the Netherlands. Chemosphere 2002, 49, 75-83.
    • (2002) Chemosphere , vol.49 , pp. 75-83
    • Bosveld, A.T.C.1    de Bie, P.A.F.2    van den Brink, N.W.3    Jongepier, H.4    Klomp, A.V.5
  • 5
    • 0026448671 scopus 로고
    • Evaluation of exposure to polycyclic aromatic hydrocarbons in a coke production and a graphite electrode manufacturing plant: Assessment of urinary excretion of 1-hydroxypyrene as a biological indicator of exposure
    • Buchet JP, Gennart JP, Mercado-Calderon F, Delavignette JP, Cupers L, Lauwerys R. Evaluation of exposure to polycyclic aromatic hydrocarbons in a coke production and a graphite electrode manufacturing plant: assessment of urinary excretion of 1-hydroxypyrene as a biological indicator of exposure. Br J Ind Med 1992, 49, 761-768.
    • (1992) Br J Ind Med , vol.49 , pp. 761-768
    • Buchet, J.P.1    Gennart, J.P.2    Mercado-Calderon, F.3    Delavignette, J.P.4    Cupers, L.5    Lauwerys, R.6
  • 6
    • 0026564746 scopus 로고
    • An examination of the time course from human dietary exposure to polycyclic aromatic hydrocarbons to urinary elimination of 1-hydroxypyrene
    • Buckley TJ, Loiy PJ. An examination of the time course from human dietary exposure to polycyclic aromatic hydrocarbons to urinary elimination of 1-hydroxypyrene. Br J Ind Med 1992, 49, 113-124.
    • (1992) Br J Ind Med , vol.49 , pp. 113-124
    • Buckley, T.J.1    Loiy, P.J.2
  • 7
    • 0027251036 scopus 로고
    • Assessment of carcinogenic risk from personal exposure to benzo(a)pyrene in the total human environmental exposure study (THEES)
    • Bulter JP, Post GB, Lioy PJ, Waldman JM, Greenberg A. Assessment of carcinogenic risk from personal exposure to benzo(a)pyrene in the total human environmental exposure study (THEES). Air Waste 1993, 43, 970-977.
    • (1993) Air Waste , vol.43 , pp. 970-977
    • Bulter, J.P.1    Post, G.B.2    Lioy, P.J.3    Waldman, J.M.4    Greenberg, A.5
  • 8
    • 0022357068 scopus 로고
    • Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P-450
    • Burke MD, Thompson S, Elcombe CR, Halpert J, Haaparanta T, Mayer RT. Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. Biochem Pharmacol 1985, 34, 3337-3345.
    • (1985) Biochem Pharmacol , vol.34 , pp. 3337-3345
    • Burke, M.D.1    Thompson, S.2    Elcombe, C.R.3    Halpert, J.4    Haaparanta, T.5    Mayer, R.T.6
  • 9
    • 0001133598 scopus 로고    scopus 로고
    • Evaluation of analysis of polycyclic aromatic hydrocarbons in meat products by liquid chromatography
    • Chen BH, Wang CY, Chiu CP. Evaluation of analysis of polycyclic aromatic hydrocarbons in meat products by liquid chromatography. J Agric Food Chem 1996, 44, 2244-2251.
    • (1996) J Agric Food Chem , vol.44 , pp. 2244-2251
    • Chen, B.H.1    Wang, C.Y.2    Chiu, C.P.3
  • 10
    • 0026048250 scopus 로고
    • Factors affecting the polycyclic aromatic hydrocarbon content of cereals, fats and other food products
    • Dennis MJ, Massey RC, Cripps G, Venn I, Howarth N, Lee G. Factors affecting the polycyclic aromatic hydrocarbon content of cereals, fats and other food products. Food Addit Contam 1991, 8, 517-530.
    • (1991) Food Addit Contam , vol.8 , pp. 517-530
    • Dennis, M.J.1    Massey, R.C.2    Cripps, G.3    Venn, I.4    Howarth, N.5    Lee, G.6
  • 11
    • 0036167445 scopus 로고    scopus 로고
    • Preliminary examination of contaminant loadings in farmed salmon, wild salmon and commercial salmon feed
    • Easton MPL, Luszinak D, Geest EV. Preliminary examination of contaminant loadings in farmed salmon, wild salmon and commercial salmon feed. Chemosphere 2002, 46, 1053-1074.
    • (2002) Chemosphere , vol.46 , pp. 1053-1074
    • Easton, M.P.L.1    Luszinak, D.2    Geest, E.V.3
  • 12
    • 0345214498 scopus 로고    scopus 로고
    • Bioavailability of PCBs to male laboratory rats maintained on litters of contaminated soils: PCB burden and induction of alkoxyresorufin O-dealkylase activities in liver and lung
    • Fouchecourt MO, Berny P, Riviere JL. Bioavailability of PCBs to male laboratory rats maintained on litters of contaminated soils: PCB burden and induction of alkoxyresorufin O-dealkylase activities in liver and lung. Arch Environ Contam Toxicol 1998, 35, 680-687.
    • (1998) Arch Environ Contam Toxicol , vol.35 , pp. 680-687
    • Fouchecourt, M.O.1    Berny, P.2    Riviere, J.L.3
  • 14
    • 0024951701 scopus 로고
    • DNA-carcinogen interaction: Covalent DNA-adducts of benzo(a)pyrene 7,8-dihydrodiol-9,10-epoxides studied by biochemical and biophysical techniques
    • Gräslund A, Jernström B. DNA-carcinogen interaction: covalent DNA-adducts of benzo(a)pyrene 7,8-dihydrodiol-9,10-epoxides studied by biochemical and biophysical techniques. Q Rev Biophys 1989, 22, 1-37.
    • (1989) Q Rev Biophys , vol.22 , pp. 1-37
    • Gräslund, A.1    Jernström, B.2
  • 15
    • 0036121707 scopus 로고    scopus 로고
    • Juvenile sea bass liver P450, EROD induction, and erythrocytic genotoxic responses to PAH and PAH-like compounds
    • Gravato C, Santos MA. Juvenile sea bass liver P450, EROD induction, and erythrocytic genotoxic responses to PAH and PAH-like compounds. Ecotoxicol Environ Saf 2002, 51, 115-127.
    • (2002) Ecotoxicol Environ Saf , vol.51 , pp. 115-127
    • Gravato, C.1    Santos, M.A.2
  • 16
    • 0142012861 scopus 로고    scopus 로고
    • Occupational exposure to polycyclic aromatic hydrocarbons in a fireproof stone producing plant: Biological monitoring of 1-hydroxypyrene, 1-, 2-, 3- and 4-hydroxyphenanthrene, 3-hydroxybenz(a)anthracene and 3-hydroxybenzo(a)pyrene
    • Gündel J, Schaller KH, Angerer J. Occupational exposure to polycyclic aromatic hydrocarbons in a fireproof stone producing plant: biological monitoring of 1-hydroxypyrene, 1-, 2-, 3- and 4-hydroxyphenanthrene, 3-hydroxybenz(a)anthracene and 3-hydroxybenzo(a)pyrene. Int Arch Occup Environ Health 2000, 73, 270-274.
    • (2000) Int Arch Occup Environ Health , vol.73 , pp. 270-274
    • Gündel, J.1    Schaller, K.H.2    Angerer, J.3
  • 17
  • 18
    • 0021006405 scopus 로고
    • IARC Monographs on the Evaluation of Carcinogenic Risk to Human. IARC, Lyon
    • IARC. IARC Monographs on the Evaluation of Carcinogenic Risk to Human. Vol. 32, p. 211, IARC, Lyon, 1983.
    • (1983) IARC , vol.32 , pp. 211
  • 19
    • 0345466475 scopus 로고    scopus 로고
    • HPLC analysis of benzo[a]pyrene-albumin adducts in benzo[a]pyrene exposed rats. Detection of cis-tetrols arising from hydrolysis of adducts of anti- and syn-BPDE III with proteins
    • Islam GA, Greibrok T, Harvey RG, Øverebø S. HPLC analysis of benzo[a]pyrene-albumin adducts in benzo[a]pyrene exposed rats. Detection of cis-tetrols arising from hydrolysis of adducts of anti- and syn-BPDE III with proteins. Chem Biol Interact 1999, 123, 133-148.
    • (1999) Chem Biol Interact , vol.123 , pp. 133-148
    • Islam, G.A.1    Greibrok, T.2    Harvey, R.G.3    Øverebø, S.4
  • 20
    • 0030321495 scopus 로고    scopus 로고
    • Metabolism and excretion of polycyclic aromatic hydrocarbons in rat and in human
    • Jacob J, Grimmer G. Metabolism and excretion of polycyclic aromatic hydrocarbons in rat and in human. Cent Eur J Public Health 1996, 4, 33-39.
    • (1996) Cent Eur J Public Health , vol.4 , pp. 33-39
    • Jacob, J.1    Grimmer, G.2
  • 22
    • 0023927119 scopus 로고
    • 1-hydroxypyrene in urine as a biological indicator of exposure to polycyclic aromatic hydrocarbons in several work environments
    • Jongeneelen FJ, Anizon RBM, Scheepers PTJ. 1-hydroxypyrene in urine as a biological indicator of exposure to polycyclic aromatic hydrocarbons in several work environments. Ann Occup Hyg 1988, 32, 35-43.
    • (1988) Ann Occup Hyg , vol.32 , pp. 35-43
    • Jongeneelen, F.J.1    Anizon, R.B.M.2    Scheepers, P.T.J.3
  • 23
    • 0035190163 scopus 로고    scopus 로고
    • Benchmark guideline for urinary 1- as biomarker of occupational exposure to polycyclic aromatic hydrocarbon
    • Jongeneelen FJ. Benchmark guideline for urinary 1- as biomarker of occupational exposure to polycyclic aromatic hydrocarbon. Ann Occup Hyg 2001, 45, 3-13.
    • (2001) Ann Occup Hyg , vol.45 , pp. 3-13
    • Jongeneelen, F.J.1
  • 24
    • 0035054201 scopus 로고    scopus 로고
    • Analysis of 200 food items for benzo[a]pyrene and estimation of its intake in an epidemiologic study
    • Kazerouni N, Shinha R, Hsu CH, Greenberg A, Rothman N. Analysis of 200 food items for benzo[a]pyrene and estimation of its intake in an epidemiologic study. Food Chem Toxicol 2001, 39, 423-436.
    • (2001) Food Chem Toxicol , vol.39 , pp. 423-436
    • Kazerouni, N.1    Shinha, R.2    Hsu, C.H.3    Greenberg, A.4    Rothman, N.5
  • 25
    • 0020520061 scopus 로고
    • Identification of 1-hydroxypyrene as a major metabolite of pyrene in pig urine
    • Keimig SD, Kiby KW, Morgna PP. Identification of 1-hydroxypyrene as a major metabolite of pyrene in pig urine. Xenobiotica 1983, 13, 415-420.
    • (1983) Xenobiotica , vol.13 , pp. 415-420
    • Keimig, S.D.1    Kiby, K.W.2    Morgna, P.P.3
  • 26
    • 0036123102 scopus 로고    scopus 로고
    • Analysis of 8-oxo-7,8-dihydro-2′- deoxyguanosine and DNA strand breaks in white blood cells of occupationally exposed workers: Comparison with ambient monitoring, urinary metabolites and enzyme polymorphisms
    • Marczynski B, Rihs HP, Rossbach B, Holzer J, Angerer J, Scherenberg M, Hoffmann G, Bruning T, Wilhelm M. Analysis of 8-oxo-7,8-dihydro-2′- deoxyguanosine and DNA strand breaks in white blood cells of occupationally exposed workers: comparison with ambient monitoring, urinary metabolites and enzyme polymorphisms. Carcinogenesis 2002, 23, 273-281.
    • (2002) Carcinogenesis , vol.23 , pp. 273-281
    • Marczynski, B.1    Rihs, H.P.2    Rossbach, B.3    Holzer, J.4    Angerer, J.5    Scherenberg, M.6    Hoffmann, G.7    Bruning, T.8    Wilhelm, M.9
  • 27
    • 0018731663 scopus 로고
    • Distribution, retention, and elimination of pyrene in rats after inhalation
    • Mitchell CE, Tu KW. Distribution, retention, and elimination of pyrene in rats after inhalation. J Toxicol Environ Health 1979, 5, 1171-1179.
    • (1979) J Toxicol Environ Health , vol.5 , pp. 1171-1179
    • Mitchell, C.E.1    Tu, K.W.2
  • 28
    • 77957175876 scopus 로고
    • Chemical structures and time-dependent effects of polycyclic aromatic hydrocarbon-type inducers on rat liver cytochrome P450, DNA adducts, and I-compounds
    • Moorthy B, Sriram P, Randerath K. Chemical structures and time-dependent effects of polycyclic aromatic hydrocarbon-type inducers on rat liver cytochrome P450, DNA adducts, and I-compounds. Fundamental Appl Toxicol 1994, 22, 549-560.
    • (1994) Fundamental Appl Toxicol , vol.22 , pp. 549-560
    • Moorthy, B.1    Sriram, P.2    Randerath, K.3
  • 30
    • 0027094098 scopus 로고
    • Toxic equivalency factors (TEFs) for polycyclic aromatic hydrocarbons
    • Nisbet ICT, LaGoy PK. Toxic equivalency factors (TEFs) for polycyclic aromatic hydrocarbons. Regul Toxicol Pharmacol 1992, 16, 290-300.
    • (1992) Regul Toxicol Pharmacol , vol.16 , pp. 290-300
    • Nisbet, I.C.T.1    LaGoy, P.K.2
  • 31
    • 0028210457 scopus 로고
    • Biological monitoring of exposure to polycyclic aromatic hydrocarbon in an electrode paste plant
    • Ovrebo S, Haugen A, Fjeldstad PE, Hemminkj K, Szyfter, K. Biological monitoring of exposure to polycyclic aromatic hydrocarbon in an electrode paste plant. J Occup Med 1994, 36, 303-310.
    • (1994) J Occup Med , vol.36 , pp. 303-310
    • Ovrebo, S.1    Haugen, A.2    Fjeldstad, P.E.3    Hemminkj, K.4    Szyfter, K.5
  • 32
    • 0036280385 scopus 로고    scopus 로고
    • Atomospheric polycyclic aromatic hydrocarbons in Seoul, Korea
    • Park SS, Kim YJ, Kang CH. Atomospheric polycyclic aromatic hydrocarbons in Seoul, Korea. Atmos Environ 2002, 36, 2917-2924.
    • (2002) Atmos Environ , vol.36 , pp. 2917-2924
    • Park, S.S.1    Kim, Y.J.2    Kang, C.H.3
  • 33
    • 0344834245 scopus 로고
    • BaP metabolism and DNA -adduct formation in cultured human lymphocytes treated in vitro with BaP and BaP-7,8-dihydrodiol
    • Parvanello S, Zanesi N, Levis AG. BaP metabolism and DNA -adduct formation in cultured human lymphocytes treated in vitro with BaP and BaP-7,8-dihydrodiol. ATLA 1992, 20, 126-137.
    • (1992) ATLA , vol.20 , pp. 126-137
    • Parvanello, S.1    Zanesi, N.2    Levis, A.G.3
  • 34
    • 0032995694 scopus 로고    scopus 로고
    • HPLC/fluorescence determination of anti-BPDE-DNA adducts in mononuclear white blood cells from PAH-exposed humans
    • Pavanello S, Favretto D, Brugnone F, Mastrangelo G, Dal Pra G, Clonfero E. HPLC/fluorescence determination of anti-BPDE-DNA adducts in mononuclear white blood cells from PAH-exposed humans. Carcinogenesis 1999, 20, 431-435.
    • (1999) Carcinogenesis , vol.20 , pp. 431-435
    • Pavanello, S.1    Favretto, D.2    Brugnone, F.3    Mastrangelo, G.4    Dal Pra, G.5    Clonfero, E.6
  • 35
    • 0019219257 scopus 로고
    • A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fraction
    • Pohl RJ, Fouts JR. A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fraction. Anal Biochem 1980, 107, 150-155.
    • (1980) Anal Biochem , vol.107 , pp. 150-155
    • Pohl, R.J.1    Fouts, J.R.2
  • 36
    • 0028181688 scopus 로고
    • Validation of a new fluorimetric assay for benzo[a]pyrene diolepoxide-DNA adducts in human white blood cells: Comparisons with 32P-postlabeling and ELISA
    • Rojas M, Alexandrov K, von Schooten FS, Hillebrand M, Kriek E, Barstch H. Validation of a new fluorimetric assay for benzo[a]pyrene diolepoxide-DNA adducts in human white blood cells: comparisons with 32P-postlabeling and ELISA. Carcinogenesis 1995, 15, 557-560.
    • (1995) Carcinogenesis , vol.15 , pp. 557-560
    • Rojas, M.1    Alexandrov, K.2    von Schooten, F.S.3    Hillebrand, M.4    Kriek, E.5    Barstch, H.6
  • 37
    • 4744360928 scopus 로고    scopus 로고
    • Risk potentials for humans of original and remediated PAH-contaminated soils: Application of biomarkers of effect
    • Roos PH, Tschirbs S, Pfeifer F, Welge P, Hack A, Wilhelm M, Bolt HM. Risk potentials for humans of original and remediated PAH-contaminated soils: application of biomarkers of effect. Toxicology 2004, 205, 181-194.
    • (2004) Toxicology , vol.205 , pp. 181-194
    • Roos, P.H.1    Tschirbs, S.2    Pfeifer, F.3    Welge, P.4    Hack, A.5    Wilhelm, M.6    Bolt, H.M.7
  • 38
    • 0029656093 scopus 로고    scopus 로고
    • Liver microsomal levels of cytochrome P450IA1 as biomarker for exposure and bioavailability of soil-bound polycyclic aromatic hydrocarbons
    • Roos PH, van Afferden M, Strotkamp D, Tappe D, Pfeifer F, Hanstein WG. Liver microsomal levels of cytochrome P450IA1 as biomarker for exposure and bioavailability of soil-bound polycyclic aromatic hydrocarbons. Arch Environ Contam Toxicol 1996, 30, 107-113.
    • (1996) Arch Environ Contam Toxicol , vol.30 , pp. 107-113
    • Roos, P.H.1    van Afferden, M.2    Strotkamp, D.3    Tappe, D.4    Pfeifer, F.5    Hanstein, W.G.6
  • 39
    • 0037165499 scopus 로고    scopus 로고
    • Modulation of neurotoxic behavior in F-344 rats by temporal disposition of benzo(a)pyrene
    • Saunders CR, Ramesh A, Shockley DC. Modulation of neurotoxic behavior in F-344 rats by temporal disposition of benzo(a)pyrene. Toxicol Lett 2002, 129, 33-45.
    • (2002) Toxicol Lett , vol.129 , pp. 33-45
    • Saunders, C.R.1    Ramesh, A.2    Shockley, D.C.3
  • 40
    • 0000034397 scopus 로고    scopus 로고
    • Relevance of different biological assays in assessing initiating and promoting properties of polycyclic aromatic hydrocarbons with respect to carcinogenic potency
    • Sjögren M, Ehrenbrg L, Rannug U. Relevance of different biological assays in assessing initiating and promoting properties of polycyclic aromatic hydrocarbons with respect to carcinogenic potency. Mutat Res 1996, 358, 97-112.
    • (1996) Mutat Res , vol.358 , pp. 97-112
    • Sjögren, M.1    Ehrenbrg, L.2    Rannug, U.3
  • 41
    • 37349038752 scopus 로고    scopus 로고
    • WHO. Evaluation of Certain Food Additives and Contaminants; Benzo(a)pyrene. WHO Food Additives Series 28. pp. 27-29, WHO, Geneva, 1998.
    • WHO. Evaluation of Certain Food Additives and Contaminants; Benzo(a)pyrene. WHO Food Additives Series 28. pp. 27-29, WHO, Geneva, 1998.
  • 42
    • 0035894365 scopus 로고    scopus 로고
    • In vivo and in vitro inhibition of CYP1A-dependent activity in Fundulus heteroclitus by the polynuclear aromatic hydrocarbon fluoranthene
    • Willett KL, Wassenberg D, Lienesch L, Reichert W, Di Giulio RT. In vivo and in vitro inhibition of CYP1A-dependent activity in Fundulus heteroclitus by the polynuclear aromatic hydrocarbon fluoranthene. Toxicol Appl Pharmacol 2001, 177, 264-271.
    • (2001) Toxicol Appl Pharmacol , vol.177 , pp. 264-271
    • Willett, K.L.1    Wassenberg, D.2    Lienesch, L.3    Reichert, W.4    Di Giulio, R.T.5
  • 43
    • 0025782582 scopus 로고
    • Pharmacokinetics and bioavailability of pyrene in the rat
    • Withey JR, Law FC, Endrenyi L. Pharmacokinetics and bioavailability of pyrene in the rat. J Toxicol Environ Health 1991, 32, 429-447.
    • (1991) J Toxicol Environ Health , vol.32 , pp. 429-447
    • Withey, J.R.1    Law, F.C.2    Endrenyi, L.3
  • 44
    • 0030200744 scopus 로고    scopus 로고
    • Fluoranthecene-induced apoptosis in murine T cell hybridomas is independent of the aromatic hydrocarbon receptor
    • Yamaguchi K, Near R, Shneider A, Cui H, Ju ST, Sherr DH. Fluoranthecene-induced apoptosis in murine T cell hybridomas is independent of the aromatic hydrocarbon receptor. Toxicol Appl Pharmacol 1996, 139, 144-152.
    • (1996) Toxicol Appl Pharmacol , vol.139 , pp. 144-152
    • Yamaguchi, K.1    Near, R.2    Shneider, A.3    Cui, H.4    Ju, S.T.5    Sherr, D.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.