Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1

Cancer Science

Volumn 95, Issue 1, 2004, Pages 1-6

  Shimada, Tsutomu ^a,b   Fujii Kuriyama, Yoshiaki ^c,d  

^a OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; CARCINOGEN; CELL DNA; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DIBENZO[A,L]PYRENE; DRUG METABOLIZING ENZYME; ENVIRONMENTAL CHEMICAL; EPOXIDE; EPOXIDE HYDROLASE; POLYCYCLIC AROMATIC HYDROCARBON; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; CANCER SUSCEPTIBILITY; CARCINOGENICITY; CATALYSIS; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; GENE EXPRESSION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; KNOCKOUT MOUSE; METABOLIC ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; WILD TYPE;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BIOTRANSFORMATION; CARCINOGENS, ENVIRONMENTAL; CYTOCHROME P-450 CYP1A1; GENETIC PREDISPOSITION TO DISEASE; HUMANS; POLYCYCLIC HYDROCARBONS, AROMATIC;

EID: 1142275258     PISSN: 13479032     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2004.tb03162.x     Document Type: Review

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