-
1
-
-
85046493350
-
Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease
-
Agostini, M.L., Andres, E.L., Sims, A.C., Graham, R.L., Sheahan, T.P., Lu, X., Smith, E.C., Case, J.B., Feng, J.Y., Jordan, R., Ray, A.S., Cihlar, T., Siegel, D., Mackman, R.L., Clarke, M.O., Baric, R.S., Denison, M.R., Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease. mBio, 9, 2018.
-
(2018)
mBio
, vol.9
-
-
Agostini, M.L.1
Andres, E.L.2
Sims, A.C.3
Graham, R.L.4
Sheahan, T.P.5
Lu, X.6
Smith, E.C.7
Case, J.B.8
Feng, J.Y.9
Jordan, R.10
Ray, A.S.11
Cihlar, T.12
Siegel, D.13
Mackman, R.L.14
Clarke, M.O.15
Baric, R.S.16
Denison, M.R.17
-
2
-
-
84963813156
-
Treatment outcomes for patients with middle eastern respiratory syndrome coronavirus (MERS CoV) infection at a coronavirus referral center in the Kingdom of Saudi Arabia
-
Al Ghamdi, M., Alghamdi, K.M., Ghandoora, Y., Alzahrani, A., Salah, F., Alsulami, A., Bawayan, M.F., Vaidya, D., Perl, T.M., Sood, G., Treatment outcomes for patients with middle eastern respiratory syndrome coronavirus (MERS CoV) infection at a coronavirus referral center in the Kingdom of Saudi Arabia. BMC Infect. Dis., 16, 2016, 174.
-
(2016)
BMC Infect. Dis.
, vol.16
, pp. 174
-
-
Al Ghamdi, M.1
Alghamdi, K.M.2
Ghandoora, Y.3
Alzahrani, A.4
Salah, F.5
Alsulami, A.6
Bawayan, M.F.7
Vaidya, D.8
Perl, T.M.9
Sood, G.10
-
3
-
-
84896695450
-
Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study
-
Al-Tawfiq, J.A., Momattin, H., Dib, J., Memish, Z.A., Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study. Int. J. Infect. Dis. 20 (2014), 42–46.
-
(2014)
Int. J. Infect. Dis.
, vol.20
, pp. 42-46
-
-
Al-Tawfiq, J.A.1
Momattin, H.2
Dib, J.3
Memish, Z.A.4
-
4
-
-
0025275762
-
Association between respiratory syncytial virus outbreaks and lower respiratory tract deaths of infants and young children
-
Anderson, L.J., Parker, R.A., Strikas, R.L., Association between respiratory syncytial virus outbreaks and lower respiratory tract deaths of infants and young children. J. Infect. Dis. 161 (1990), 640–646.
-
(1990)
J. Infect. Dis.
, vol.161
, pp. 640-646
-
-
Anderson, L.J.1
Parker, R.A.2
Strikas, R.L.3
-
5
-
-
85019158568
-
Further evidence for bats as the evolutionary source of Middle East respiratory syndrome coronavirus
-
Anthony, S.J., Gilardi, K., Menachery, V.D., Goldstein, T., Ssebide, B., Mbabazi, R., Navarrete-Macias, I., Liang, E., Wells, H., Hicks, A., Petrosov, A., Byarugaba, D.K., Debbink, K., Dinnon, K.H., Scobey, T., Randell, S.H., Yount, B.L., Cranfield, M., Johnson, C.K., Baric, R.S., Lipkin, W.I., Mazet, J.A., Further evidence for bats as the evolutionary source of Middle East respiratory syndrome coronavirus. mBio, 8, 2017.
-
(2017)
mBio
, vol.8
-
-
Anthony, S.J.1
Gilardi, K.2
Menachery, V.D.3
Goldstein, T.4
Ssebide, B.5
Mbabazi, R.6
Navarrete-Macias, I.7
Liang, E.8
Wells, H.9
Hicks, A.10
Petrosov, A.11
Byarugaba, D.K.12
Debbink, K.13
Dinnon, K.H.14
Scobey, T.15
Randell, S.H.16
Yount, B.L.17
Cranfield, M.18
Johnson, C.K.19
Baric, R.S.20
Lipkin, W.I.21
Mazet, J.A.22
more..
-
6
-
-
84947763505
-
Feasibility, safety, clinical, and laboratory effects of convalescent plasma therapy for patients with Middle East respiratory syndrome coronavirus infection: a study protocol
-
Arabi, Y., Balkhy, H., Hajeer, A.H., Bouchama, A., Hayden, F.G., Al-Omari, A., Al-Hameed, F.M., Taha, Y., Shindo, N., Whitehead, J., Merson, L., AlJohani, S., Al-Khairy, K., Carson, G., Luke, T.C., Hensley, L., Al-Dawood, A., Al-Qahtani, S., Modjarrad, K., Sadat, M., Rohde, G., Leport, C., Fowler, R., Feasibility, safety, clinical, and laboratory effects of convalescent plasma therapy for patients with Middle East respiratory syndrome coronavirus infection: a study protocol. SpringerPlus, 4, 2015, 709.
-
(2015)
SpringerPlus
, vol.4
, pp. 709
-
-
Arabi, Y.1
Balkhy, H.2
Hajeer, A.H.3
Bouchama, A.4
Hayden, F.G.5
Al-Omari, A.6
Al-Hameed, F.M.7
Taha, Y.8
Shindo, N.9
Whitehead, J.10
Merson, L.11
AlJohani, S.12
Al-Khairy, K.13
Carson, G.14
Luke, T.C.15
Hensley, L.16
Al-Dawood, A.17
Al-Qahtani, S.18
Modjarrad, K.19
Sadat, M.20
Rohde, G.21
Leport, C.22
Fowler, R.23
more..
-
7
-
-
85064726333
-
Effect of ribavirin and interferon on the outcome of critically ill patients with MERS
-
Arabi, Y.M., Shalhoub, S., Omari, A.A., Mandourah, Y., Al-Hameed, F., Sindi, A., Alraddadi, B., Motairi, A.A., Khatib, K.A., Mommin, A.A., Qushmaq, I.A., Mady, A., Solaiman, O., Aithan, A.A., Balkhy, H.H., Al-Raddadi, R., Rajab, A., Mekhlafi, G.A.A., Harthy, A.A., Kharaba, A., Al-Jabbary, A., Pinto, R., Sadat, M., Mutairi, H.A., Qasim, E.A., Jose, J., Deeb, A.M., Merson, L., Hayden, F.G., Fowler, R., Aldawood, A.S., Effect of ribavirin and interferon on the outcome of critically ill patients with MERS. Am. J. Respir. Crit. Care Med., 195, 2017, A6067.
-
(2017)
Am. J. Respir. Crit. Care Med.
, vol.195
, pp. A6067
-
-
Arabi, Y.M.1
Shalhoub, S.2
Omari, A.A.3
Mandourah, Y.4
Al-Hameed, F.5
Sindi, A.6
Alraddadi, B.7
Motairi, A.A.8
Khatib, K.A.9
Mommin, A.A.10
Qushmaq, I.A.11
Mady, A.12
Solaiman, O.13
Aithan, A.A.14
Balkhy, H.H.15
Al-Raddadi, R.16
Rajab, A.17
Mekhlafi, G.A.A.18
Harthy, A.A.19
Kharaba, A.20
Al-Jabbary, A.21
Pinto, R.22
Sadat, M.23
Mutairi, H.A.24
Qasim, E.A.25
Jose, J.26
Deeb, A.M.27
Merson, L.28
Hayden, F.G.29
Fowler, R.30
Aldawood, A.S.31
more..
-
8
-
-
84978216553
-
Feasibility of a randomized controlled trial to assess treatment of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection in Saudi Arabia: a survey of physicians
-
Arabi, Y.M., Al-Enezi, F., Longuere, K.S., Balkhy, H.H., Al-Sultan, M., Al-Omari, A., Al-Hameed, F.M., Carson, G., Shindo, N., Fowler, R., Feasibility of a randomized controlled trial to assess treatment of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection in Saudi Arabia: a survey of physicians. BMC Anesthesiol., 16, 2016, 36.
-
(2016)
BMC Anesthesiol.
, vol.16
, pp. 36
-
-
Arabi, Y.M.1
Al-Enezi, F.2
Longuere, K.S.3
Balkhy, H.H.4
Al-Sultan, M.5
Al-Omari, A.6
Al-Hameed, F.M.7
Carson, G.8
Shindo, N.9
Fowler, R.10
-
9
-
-
85041331786
-
Treatment of Middle East Respiratory Syndrome with a combination of lopinavir-ritonavir and interferon-beta1b (MIRACLE trial): study protocol for a randomized controlled trial
-
Arabi, Y.M., Alothman, A., Balkhy, H.H., Al-Dawood, A., AlJohani, S., Al Harbi, S., Kojan, S., Al Jeraisy, M., Deeb, A.M., Assiri, A.M., Al-Hameed, F., AlSaedi, A., Mandourah, Y., Almekhlafi, G.A., Sherbeeni, N.M., Elzein, F.E., Memon, J., Taha, Y., Almotairi, A., Maghrabi, K.A., Qushmaq, I., Al Bshabshe, A., Kharaba, A., Shalhoub, S., Jose, J., Fowler, R.A., Hayden, F.G., Hussein, M.A., the, M.t.g. Treatment of Middle East Respiratory Syndrome with a combination of lopinavir-ritonavir and interferon-beta1b (MIRACLE trial): study protocol for a randomized controlled trial. Trials, 19, 2018, 81.
-
(2018)
Trials
, vol.19
, pp. 81
-
-
Arabi, Y.M.1
Alothman, A.2
Balkhy, H.H.3
Al-Dawood, A.4
AlJohani, S.5
Al Harbi, S.6
Kojan, S.7
Al Jeraisy, M.8
Deeb, A.M.9
Assiri, A.M.10
Al-Hameed, F.11
AlSaedi, A.12
Mandourah, Y.13
Almekhlafi, G.A.14
Sherbeeni, N.M.15
Elzein, F.E.16
Memon, J.17
Taha, Y.18
Almotairi, A.19
Maghrabi, K.A.20
Qushmaq, I.21
Al Bshabshe, A.22
Kharaba, A.23
Shalhoub, S.24
Jose, J.25
Fowler, R.A.26
Hayden, F.G.27
Hussein, M.A.28
more..
-
10
-
-
85012850972
-
Middle East respiratory syndrome
-
Arabi, Y.M., Balkhy, H.H., Hayden, F.G., Bouchama, A., Luke, T., Baillie, J.K., Al-Omari, A., Hajeer, A.H., Senga, M., Denison, M.R., Nguyen-Van-Tam, J.S., Shindo, N., Bermingham, A., Chappell, J.D., Van Kerkhove, M.D., Fowler, R.A., Middle East respiratory syndrome. N. Engl. J. Med. 376 (2017), 584–594.
-
(2017)
N. Engl. J. Med.
, vol.376
, pp. 584-594
-
-
Arabi, Y.M.1
Balkhy, H.H.2
Hayden, F.G.3
Bouchama, A.4
Luke, T.5
Baillie, J.K.6
Al-Omari, A.7
Hajeer, A.H.8
Senga, M.9
Denison, M.R.10
Nguyen-Van-Tam, J.S.11
Shindo, N.12
Bermingham, A.13
Chappell, J.D.14
Van Kerkhove, M.D.15
Fowler, R.A.16
-
11
-
-
85045205939
-
Corticosteroid therapy for critically ill patients with Middle East respiratory syndrome
-
Arabi, Y.M., Mandourah, Y., Al-Hameed, F., Sindi, A.A., Almekhlafi, G.A., Hussein, M.A., Jose, J., Pinto, R., Al-Omari, A., Kharaba, A., Almotairi, A., Al Khatib, K., Alraddadi, B., Shalhoub, S., Abdulmomen, A., Qushmaq, I., Mady, A., Solaiman, O., Al-Aithan, A.M., Al-Raddadi, R., Ragab, A., Balkhy, H.H., Al Harthy, A., Deeb, A.M., Al Mutairi, H., Al-Dawood, A., Merson, L., Hayden, F.G., Fowler, R.A., Saudi Critical Care Trial, G. Corticosteroid therapy for critically ill patients with Middle East respiratory syndrome. Am. J. Respir. Crit. Care Med. 197 (2018), 757–767.
-
(2018)
Am. J. Respir. Crit. Care Med.
, vol.197
, pp. 757-767
-
-
Arabi, Y.M.1
Mandourah, Y.2
Al-Hameed, F.3
Sindi, A.A.4
Almekhlafi, G.A.5
Hussein, M.A.6
Jose, J.7
Pinto, R.8
Al-Omari, A.9
Kharaba, A.10
Almotairi, A.11
Al Khatib, K.12
Alraddadi, B.13
Shalhoub, S.14
Abdulmomen, A.15
Qushmaq, I.16
Mady, A.17
Solaiman, O.18
Al-Aithan, A.M.19
Al-Raddadi, R.20
Ragab, A.21
Balkhy, H.H.22
Al Harthy, A.23
Deeb, A.M.24
Al Mutairi, H.25
Al-Dawood, A.26
Merson, L.27
Hayden, F.G.28
Fowler, R.A.29
more..
-
12
-
-
72049131299
-
Emergence of H274Y oseltamivir-resistant A(H1N1) influenza viruses in Japan during the 2008-2009 season
-
Baranovich, T., Saito, R., Suzuki, Y., Zaraket, H., Dapat, C., Caperig-Dapat, I., Oguma, T., Shabana, I.I., Saito, T., Suzuki, H., Japanese Influenza Collaborative Study, G. Emergence of H274Y oseltamivir-resistant A(H1N1) influenza viruses in Japan during the 2008-2009 season. J. Clin. Virol. 47 (2010), 23–28.
-
(2010)
J. Clin. Virol.
, vol.47
, pp. 23-28
-
-
Baranovich, T.1
Saito, R.2
Suzuki, Y.3
Zaraket, H.4
Dapat, C.5
Caperig-Dapat, I.6
Oguma, T.7
Shabana, I.I.8
Saito, T.9
Suzuki, H.10
-
13
-
-
84962463234
-
Current practices for treatment of respiratory syncytial virus and other non-influenza respiratory viruses in high-risk patient populations: a survey of institutions in the Midwestern respiratory virus collaborative
-
Beaird, O.E., Freifeld, A., Ison, M.G., Lawrence, S.J., Theodoropoulos, N., Clark, N.M., Razonable, R.R., Alangaden, G., Miller, R., Smith, J., Young, J.A., Hawkinson, D., Pursell, K., Kaul, D.R., Current practices for treatment of respiratory syncytial virus and other non-influenza respiratory viruses in high-risk patient populations: a survey of institutions in the Midwestern respiratory virus collaborative. Transpl. Infect. Dis. 18 (2016), 210–215.
-
(2016)
Transpl. Infect. Dis.
, vol.18
, pp. 210-215
-
-
Beaird, O.E.1
Freifeld, A.2
Ison, M.G.3
Lawrence, S.J.4
Theodoropoulos, N.5
Clark, N.M.6
Razonable, R.R.7
Alangaden, G.8
Miller, R.9
Smith, J.10
Young, J.A.11
Hawkinson, D.12
Pursell, K.13
Kaul, D.R.14
-
14
-
-
58149398620
-
Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice
-
Becker, M.M., Graham, R.L., Donaldson, E.F., Rockx, B., Sims, A.C., Sheahan, T., Pickles, R.J., Corti, D., Johnston, R.E., Baric, R.S., Denison, M.R., Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proc. Natl. Acad. Sci. U. S. A. 105 (2008), 19944–19949.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 19944-19949
-
-
Becker, M.M.1
Graham, R.L.2
Donaldson, E.F.3
Rockx, B.4
Sims, A.C.5
Sheahan, T.6
Pickles, R.J.7
Corti, D.8
Johnston, R.E.9
Baric, R.S.10
Denison, M.R.11
-
15
-
-
85019564290
-
Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study
-
Beigel, J.H., Tebas, P., Elie-Turenne, M.C., Bajwa, E., Bell, T.E., Cairns, C.B., Shoham, S., Deville, J.G., Feucht, E., Feinberg, J., Luke, T., Raviprakash, K., Danko, J., O'Neil, D., Metcalf, J.A., King, K., Burgess, T.H., Aga, E., Lane, H.C., Hughes, M.D., Davey, R.T., Team, I.R.C.S., Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study. Lancet Respir. Med. 5 (2017), 500–511.
-
(2017)
Lancet Respir. Med.
, vol.5
, pp. 500-511
-
-
Beigel, J.H.1
Tebas, P.2
Elie-Turenne, M.C.3
Bajwa, E.4
Bell, T.E.5
Cairns, C.B.6
Shoham, S.7
Deville, J.G.8
Feucht, E.9
Feinberg, J.10
Luke, T.11
Raviprakash, K.12
Danko, J.13
O'Neil, D.14
Metcalf, J.A.15
King, K.16
Burgess, T.H.17
Aga, E.18
Lane, H.C.19
Hughes, M.D.20
Davey, R.T.21
Team, I.R.C.S.22
more..
-
16
-
-
85040575647
-
Safety and tolerability of a novel, polyclonal human anti-MERS coronavirus antibody produced from transchromosomic cattle: a phase 1 randomised, double-blind, single-dose-escalation study
-
Beigel, J.H., Voell, J., Kumar, P., Raviprakash, K., Wu, H., Jiao, J.A., Sullivan, E., Luke, T., Davey, R.T. Jr., Safety and tolerability of a novel, polyclonal human anti-MERS coronavirus antibody produced from transchromosomic cattle: a phase 1 randomised, double-blind, single-dose-escalation study. Lancet Infect. Dis. 18 (2018), 410–418.
-
(2018)
Lancet Infect. Dis.
, vol.18
, pp. 410-418
-
-
Beigel, J.H.1
Voell, J.2
Kumar, P.3
Raviprakash, K.4
Wu, H.5
Jiao, J.A.6
Sullivan, E.7
Luke, T.8
Davey, R.T.9
-
17
-
-
79957983476
-
Pharmacokinetics of oseltamivir among pregnant and nonpregnant women
-
Beigi, R.H., Han, K., Venkataramanan, R., Hankins, G.D., Clark, S., Hebert, M.F., Easterling, T., Zajicek, A., Ren, Z., Mattison, D.R., Caritis, S.N., Obstetric-Fetal Pharmacology Research Units, N. Pharmacokinetics of oseltamivir among pregnant and nonpregnant women. Am. J. Obstet. Gynecol. 204 (2011), S84–S88.
-
(2011)
Am. J. Obstet. Gynecol.
, vol.204
, pp. S84-S88
-
-
Beigi, R.H.1
Han, K.2
Venkataramanan, R.3
Hankins, G.D.4
Clark, S.5
Hebert, M.F.6
Easterling, T.7
Zajicek, A.8
Ren, Z.9
Mattison, D.R.10
Caritis, S.N.11
-
18
-
-
85064140138
-
Nitazoxanide, a novel potential anti-influenza drug
-
(Boston, MA)
-
Belardo, G., Frazia, S.L., Cenciarelli, O., Carta, S., Rossignol, J.-F., Santoro, M.G., Nitazoxanide, a novel potential anti-influenza drug. Acting in Synergism with Neuraminidase Inhibitors, IDSA Poster Abstract Session, October 22, 2011, 2011 (Boston, MA).
-
(2011)
Acting in Synergism with Neuraminidase Inhibitors, IDSA Poster Abstract Session, October 22, 2011
-
-
Belardo, G.1
Frazia, S.L.2
Cenciarelli, O.3
Carta, S.4
Rossignol, J.-F.5
Santoro, M.G.6
-
19
-
-
84901011755
-
Arbidol as a broad-spectrum antiviral: an update
-
Blaising, J., Polyak, S.J., Pecheur, E.I., Arbidol as a broad-spectrum antiviral: an update. Antivir. Res. 107 (2014), 84–94.
-
(2014)
Antivir. Res.
, vol.107
, pp. 84-94
-
-
Blaising, J.1
Polyak, S.J.2
Pecheur, E.I.3
-
20
-
-
85052974420
-
Inhaled therapy in respiratory disease: the complex interplay of pulmonary kinetic processes
-
Borghardt, J.M., Kloft, C., Sharma, A., Inhaled therapy in respiratory disease: the complex interplay of pulmonary kinetic processes. Can. Respir. J., 2018, 2018, 2732017.
-
(2018)
Can. Respir. J.
, vol.2018
-
-
Borghardt, J.M.1
Kloft, C.2
Sharma, A.3
-
21
-
-
25844438380
-
Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern
-
Bright, R.A., Medina, M.J., Xu, X., Perez-Oronoz, G., Wallis, T.R., Davis, X.M., Povinelli, L., Cox, N.J., Klimov, A.I., Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern. Lancet 366 (2005), 1175–1181.
-
(2005)
Lancet
, vol.366
, pp. 1175-1181
-
-
Bright, R.A.1
Medina, M.J.2
Xu, X.3
Perez-Oronoz, G.4
Wallis, T.R.5
Davis, X.M.6
Povinelli, L.7
Cox, N.J.8
Klimov, A.I.9
-
22
-
-
84923234062
-
Preclinical activity of VX-787, a first-in-class, orally bioavailable inhibitor of the influenza virus polymerase PB2 subunit
-
Byrn, R.A., Jones, S.M., Bennett, H.B., Bral, C., Clark, M.P., Jacobs, M.D., Kwong, A.D., Ledeboer, M.W., Leeman, J.R., McNeil, C.F., Murcko, M.A., Nezami, A., Perola, E., Rijnbrand, R., Saxena, K., Tsai, A.W., Zhou, Y., Charifson, P.S., Preclinical activity of VX-787, a first-in-class, orally bioavailable inhibitor of the influenza virus polymerase PB2 subunit. Antimicrob. Agents Chemother. 59 (2015), 1569–1582.
-
(2015)
Antimicrob. Agents Chemother.
, vol.59
, pp. 1569-1582
-
-
Byrn, R.A.1
Jones, S.M.2
Bennett, H.B.3
Bral, C.4
Clark, M.P.5
Jacobs, M.D.6
Kwong, A.D.7
Ledeboer, M.W.8
Leeman, J.R.9
McNeil, C.F.10
Murcko, M.A.11
Nezami, A.12
Perola, E.13
Rijnbrand, R.14
Saxena, K.15
Tsai, A.W.16
Zhou, Y.17
Charifson, P.S.18
-
23
-
-
85064111661
-
Short period incidence sTudy of severe acute respiratory infection (SPRINT-SARI) initial data from a global observational study to better describe SARI epidemiology in critically ill patients
-
Carson, G.L., Castle, L., George, M., Horby, P., Longuere, K.S., Merson, L., Murthy, S., O'neill, G., Pardinaz-Solis, R., Webb, S., Short period incidence sTudy of severe acute respiratory infection (SPRINT-SARI) initial data from a global observational study to better describe SARI epidemiology in critically ill patients. Int. J. Infect. Dis., 53, 2016, 101.
-
(2016)
Int. J. Infect. Dis.
, vol.53
, pp. 101
-
-
Carson, G.L.1
Castle, L.2
George, M.3
Horby, P.4
Longuere, K.S.5
Merson, L.6
Murthy, S.7
O'neill, G.8
Pardinaz-Solis, R.9
Webb, S.10
-
24
-
-
64749089192
-
Update: influenza activity--United States, September 28, 2008-April 4, 2009, and composition of the 2009-10 influenza vaccine
-
Centers for Disease, C., Prevention, Update: influenza activity--United States, September 28, 2008-April 4, 2009, and composition of the 2009-10 influenza vaccine. MMWR Morb. Mortal. Wkly. Rep. 58 (2009), 369–374.
-
(2009)
MMWR Morb. Mortal. Wkly. Rep.
, vol.58
, pp. 369-374
-
-
Centers for Disease, C., Prevention,1
-
25
-
-
84887019388
-
Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus
-
Chan, J.F., Chan, K.H., Kao, R.Y., To, K.K., Zheng, B.J., Li, C.P., Li, P.T., Dai, J., Mok, F.K., Chen, H., Hayden, F.G., Yuen, K.Y., Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus. J. Infect. 67 (2013), 606–616.
-
(2013)
J. Infect.
, vol.67
, pp. 606-616
-
-
Chan, J.F.1
Chan, K.H.2
Kao, R.Y.3
To, K.K.4
Zheng, B.J.5
Li, C.P.6
Li, P.T.7
Dai, J.8
Mok, F.K.9
Chen, H.10
Hayden, F.G.11
Yuen, K.Y.12
-
26
-
-
84955391557
-
Treatment with lopinavir/ritonavir or interferon-beta1b improves outcome of MERS-CoV infection in a nonhuman primate model of common marmoset
-
Chan, J.F., Yao, Y., Yeung, M.L., Deng, W., Bao, L., Jia, L., Li, F., Xiao, C., Gao, H., Yu, P., Cai, J.P., Chu, H., Zhou, J., Chen, H., Qin, C., Yuen, K.Y., Treatment with lopinavir/ritonavir or interferon-beta1b improves outcome of MERS-CoV infection in a nonhuman primate model of common marmoset. J. Infect. Dis. 212 (2015), 1904–1913.
-
(2015)
J. Infect. Dis.
, vol.212
, pp. 1904-1913
-
-
Chan, J.F.1
Yao, Y.2
Yeung, M.L.3
Deng, W.4
Bao, L.5
Jia, L.6
Li, F.7
Xiao, C.8
Gao, H.9
Yu, P.10
Cai, J.P.11
Chu, H.12
Zhou, J.13
Chen, H.14
Qin, C.15
Yuen, K.Y.16
-
27
-
-
85030668169
-
Massively parallel de novo protein design for targeted therapeutics
-
Chevalier, A., Silva, D.A., Rocklin, G.J., Hicks, D.R., Vergara, R., Murapa, P., Bernard, S.M., Zhang, L., Lam, K.H., Yao, G., Bahl, C.D., Miyashita, S.I., Goreshnik, I., Fuller, J.T., Koday, M.T., Jenkins, C.M., Colvin, T., Carter, L., Bohn, A., Bryan, C.M., Fernandez-Velasco, D.A., Stewart, L., Dong, M., Huang, X., Jin, R., Wilson, I.A., Fuller, D.H., Baker, D., Massively parallel de novo protein design for targeted therapeutics. Nature 550 (2017), 74–79.
-
(2017)
Nature
, vol.550
, pp. 74-79
-
-
Chevalier, A.1
Silva, D.A.2
Rocklin, G.J.3
Hicks, D.R.4
Vergara, R.5
Murapa, P.6
Bernard, S.M.7
Zhang, L.8
Lam, K.H.9
Yao, G.10
Bahl, C.D.11
Miyashita, S.I.12
Goreshnik, I.13
Fuller, J.T.14
Koday, M.T.15
Jenkins, C.M.16
Colvin, T.17
Carter, L.18
Bohn, A.19
Bryan, C.M.20
Fernandez-Velasco, D.A.21
Stewart, L.22
Dong, M.23
Huang, X.24
Jin, R.25
Wilson, I.A.26
Fuller, D.H.27
Baker, D.28
more..
-
28
-
-
12144290587
-
Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings
-
Chu, C.M., Cheng, V.C., Hung, I.F., Wong, M.M., Chan, K.H., Chan, K.S., Kao, R.Y., Poon, L.L., Wong, C.L., Guan, Y., Peiris, J.S., Yuen, K.Y., Group, H.U.S.S., Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings. Thorax 59 (2004), 252–256.
-
(2004)
Thorax
, vol.59
, pp. 252-256
-
-
Chu, C.M.1
Cheng, V.C.2
Hung, I.F.3
Wong, M.M.4
Chan, K.H.5
Chan, K.S.6
Kao, R.Y.7
Poon, L.L.8
Wong, C.L.9
Guan, Y.10
Peiris, J.S.11
Yuen, K.Y.12
Group, H.U.S.S.13
-
29
-
-
85028313141
-
Preclinical characterization of PC786, an inhaled small-molecule respiratory syncytial virus L protein polymerase inhibitor
-
Coates, M., Brookes, D., Kim, Y.I., Allen, H., Fordyce, E.A.F., Meals, E.A., Colley, T., Ciana, C.L., Parra, G.F., Sherbukhin, V., Stockwell, J.A., Thomas, J.C., Hunt, S.F., Anderson-Dring, L., Onions, S.T., Cass, L., Murray, P.J., Ito, K., Strong, P., DeVincenzo, J.P., Rapeport, G., Preclinical characterization of PC786, an inhaled small-molecule respiratory syncytial virus L protein polymerase inhibitor. Antimicrob. Agents Chemother., 61, 2017.
-
(2017)
Antimicrob. Agents Chemother.
, vol.61
-
-
Coates, M.1
Brookes, D.2
Kim, Y.I.3
Allen, H.4
Fordyce, E.A.F.5
Meals, E.A.6
Colley, T.7
Ciana, C.L.8
Parra, G.F.9
Sherbukhin, V.10
Stockwell, J.A.11
Thomas, J.C.12
Hunt, S.F.13
Anderson-Dring, L.14
Onions, S.T.15
Cass, L.16
Murray, P.J.17
Ito, K.18
Strong, P.19
DeVincenzo, J.P.20
Rapeport, G.21
more..
-
30
-
-
84999652028
-
A mouse model for MERS coronavirus-induced acute respiratory distress syndrome
-
Cockrell, A.S., Yount, B.L., Scobey, T., Jensen, K., Douglas, M., Beall, A., Tang, X.C., Marasco, W.A., Heise, M.T., Baric, R.S., A mouse model for MERS coronavirus-induced acute respiratory distress syndrome. Nat. Microbiol., 2, 2016, 16226.
-
(2016)
Nat. Microbiol.
, vol.2
, pp. 16226
-
-
Cockrell, A.S.1
Yount, B.L.2
Scobey, T.3
Jensen, K.4
Douglas, M.5
Beall, A.6
Tang, X.C.7
Marasco, W.A.8
Heise, M.T.9
Baric, R.S.10
-
31
-
-
77956607815
-
Lopinavir/Ritonavir: a review of its use in the management of HIV-1 infection
-
Croxtall, J.D., Perry, C.M., Lopinavir/Ritonavir: a review of its use in the management of HIV-1 infection. Drugs 70 (2010), 1885–1915.
-
(2010)
Drugs
, vol.70
, pp. 1885-1915
-
-
Croxtall, J.D.1
Perry, C.M.2
-
32
-
-
84921953520
-
Evaluation of intravenous peramivir for treatment of influenza in hospitalized patients
-
de Jong, M.D., Ison, M.G., Monto, A.S., Metev, H., Clark, C., O'Neil, B., Elder, J., McCullough, A., Collis, P., Sheridan, W.P., Evaluation of intravenous peramivir for treatment of influenza in hospitalized patients. Clin. Infect. Dis. 59 (2014), e172–185.
-
(2014)
Clin. Infect. Dis.
, vol.59
, pp. e172-185
-
-
de Jong, M.D.1
Ison, M.G.2
Monto, A.S.3
Metev, H.4
Clark, C.5
O'Neil, B.6
Elder, J.7
McCullough, A.8
Collis, P.9
Sheridan, W.P.10
-
33
-
-
84905386648
-
Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture
-
de Wilde, A.H., Jochmans, D., Posthuma, C.C., Zevenhoven-Dobbe, J.C., van Nieuwkoop, S., Bestebroer, T.M., van den Hoogen, B.G., Neyts, J., Snijder, E.J., Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture. Antimicrob. Agents Chemother. 58 (2014), 4875–4884.
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 4875-4884
-
-
de Wilde, A.H.1
Jochmans, D.2
Posthuma, C.C.3
Zevenhoven-Dobbe, J.C.4
van Nieuwkoop, S.5
Bestebroer, T.M.6
van den Hoogen, B.G.7
Neyts, J.8
Snijder, E.J.9
-
34
-
-
84880177352
-
MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-alpha treatment
-
de Wilde, A.H., Raj, V.S., Oudshoorn, D., Bestebroer, T.M., van Nieuwkoop, S., Limpens, R.W., Posthuma, C.C., van der Meer, Y., Barcena, M., Haagmans, B.L., Snijder, E.J., van den Hoogen, B.G., MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-alpha treatment. J. Gen. Virol. 94 (2013), 1749–1760.
-
(2013)
J. Gen. Virol.
, vol.94
, pp. 1749-1760
-
-
de Wilde, A.H.1
Raj, V.S.2
Oudshoorn, D.3
Bestebroer, T.M.4
van Nieuwkoop, S.5
Limpens, R.W.6
Posthuma, C.C.7
van der Meer, Y.8
Barcena, M.9
Haagmans, B.L.10
Snijder, E.J.11
van den Hoogen, B.G.12
-
35
-
-
18944399906
-
Respiratory syncytial virus load predicts disease severity in previously healthy infants
-
DeVincenzo, J.P., El Saleeby, C.M., Bush, A.J., Respiratory syncytial virus load predicts disease severity in previously healthy infants. J. Infect. Dis. 191 (2005), 1861–1868.
-
(2005)
J. Infect. Dis.
, vol.191
, pp. 1861-1868
-
-
DeVincenzo, J.P.1
El Saleeby, C.M.2
Bush, A.J.3
-
36
-
-
84947719880
-
Activity of oral ALS-008176 in a respiratory syncytial virus challenge study
-
DeVincenzo, J.P., McClure, M.W., Symons, J.A., Fathi, H., Westland, C., Chanda, S., Lambkin-Williams, R., Smith, P., Zhang, Q., Beigelman, L., Blatt, L.M., Fry, J., Activity of oral ALS-008176 in a respiratory syncytial virus challenge study. N. Engl. J. Med. 373 (2015), 2048–2058.
-
(2015)
N. Engl. J. Med.
, vol.373
, pp. 2048-2058
-
-
DeVincenzo, J.P.1
McClure, M.W.2
Symons, J.A.3
Fathi, H.4
Westland, C.5
Chanda, S.6
Lambkin-Williams, R.7
Smith, P.8
Zhang, Q.9
Beigelman, L.10
Blatt, L.M.11
Fry, J.12
-
37
-
-
84907363348
-
Oral GS-5806 activity in a respiratory syncytial virus challenge study
-
DeVincenzo, J.P., Whitley, R.J., Mackman, R.L., Scaglioni-Weinlich, C., Harrison, L., Farrell, E., McBride, S., Lambkin-Williams, R., Jordan, R., Xin, Y., Ramanathan, S., O'Riordan, T., Lewis, S.A., Li, X., Toback, S.L., Lin, S.L., Chien, J.W., Oral GS-5806 activity in a respiratory syncytial virus challenge study. N. Engl. J. Med. 371 (2014), 711–722.
-
(2014)
N. Engl. J. Med.
, vol.371
, pp. 711-722
-
-
DeVincenzo, J.P.1
Whitley, R.J.2
Mackman, R.L.3
Scaglioni-Weinlich, C.4
Harrison, L.5
Farrell, E.6
McBride, S.7
Lambkin-Williams, R.8
Jordan, R.9
Xin, Y.10
Ramanathan, S.11
O'Riordan, T.12
Lewis, S.A.13
Li, X.14
Toback, S.L.15
Lin, S.L.16
Chien, J.W.17
-
38
-
-
78349243640
-
Viral load drives disease in humans experimentally infected with respiratory syncytial virus
-
DeVincenzo, J.P., Wilkinson, T., Vaishnaw, A., Cehelsky, J., Meyers, R., Nochur, S., Harrison, L., Meeking, P., Mann, A., Moane, E., Oxford, J., Pareek, R., Moore, R., Walsh, E., Studholme, R., Dorsett, P., Alvarez, R., Lambkin-Williams, R., Viral load drives disease in humans experimentally infected with respiratory syncytial virus. Am. J. Respir. Crit. Care Med. 182 (2010), 1305–1314.
-
(2010)
Am. J. Respir. Crit. Care Med.
, vol.182
, pp. 1305-1314
-
-
DeVincenzo, J.P.1
Wilkinson, T.2
Vaishnaw, A.3
Cehelsky, J.4
Meyers, R.5
Nochur, S.6
Harrison, L.7
Meeking, P.8
Mann, A.9
Moane, E.10
Oxford, J.11
Pareek, R.12
Moore, R.13
Walsh, E.14
Studholme, R.15
Dorsett, P.16
Alvarez, R.17
Lambkin-Williams, R.18
-
39
-
-
67249130012
-
The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit
-
Dias, A., Bouvier, D., Crepin, T., McCarthy, A.A., Hart, D.J., Baudin, F., Cusack, S., Ruigrok, R.W., The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit. Nature 458 (2009), 914–918.
-
(2009)
Nature
, vol.458
, pp. 914-918
-
-
Dias, A.1
Bouvier, D.2
Crepin, T.3
McCarthy, A.A.4
Hart, D.J.5
Baudin, F.6
Cusack, S.7
Ruigrok, R.W.8
-
40
-
-
50149084678
-
Influenza virus protecting RNA: an effective prophylactic and therapeutic antiviral
-
Dimmock, N.J., Rainsford, E.W., Scott, P.D., Marriott, A.C., Influenza virus protecting RNA: an effective prophylactic and therapeutic antiviral. J. Virol. 82 (2008), 8570–8578.
-
(2008)
J. Virol.
, vol.82
, pp. 8570-8578
-
-
Dimmock, N.J.1
Rainsford, E.W.2
Scott, P.D.3
Marriott, A.C.4
-
41
-
-
84929029181
-
Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials
-
Dobson, J., Whitley, R.J., Pocock, S., Monto, A.S., Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials. Lancet 385 (2015), 1729–1737.
-
(2015)
Lancet
, vol.385
, pp. 1729-1737
-
-
Dobson, J.1
Whitley, R.J.2
Pocock, S.3
Monto, A.S.4
-
42
-
-
85048282659
-
Recent developments in interferon-based therapies for multiple sclerosis
-
Dumitrescu, L., Constantinescu, C.S., Tanasescu, R., Recent developments in interferon-based therapies for multiple sclerosis. Expert Opin. Biol. Ther. 18 (2018), 665–680.
-
(2018)
Expert Opin. Biol. Ther.
, vol.18
, pp. 665-680
-
-
Dumitrescu, L.1
Constantinescu, C.S.2
Tanasescu, R.3
-
43
-
-
80052422367
-
Respiratory syncytial virus load, viral dynamics, and disease severity in previously healthy naturally infected children
-
El Saleeby, C.M., Bush, A.J., Harrison, L.M., Aitken, J.A., Devincenzo, J.P., Respiratory syncytial virus load, viral dynamics, and disease severity in previously healthy naturally infected children. J. Infect. Dis. 204 (2011), 996–1002.
-
(2011)
J. Infect. Dis.
, vol.204
, pp. 996-1002
-
-
El Saleeby, C.M.1
Bush, A.J.2
Harrison, L.M.3
Aitken, J.A.4
Devincenzo, J.P.5
-
45
-
-
17644392071
-
Respiratory syncytial virus infection in elderly and high-risk adults
-
Falsey, A.R., Hennessey, P.A., Formica, M.A., Cox, C., Walsh, E.E., Respiratory syncytial virus infection in elderly and high-risk adults. N. Engl. J. Med. 352 (2005), 1749–1759.
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 1749-1759
-
-
Falsey, A.R.1
Hennessey, P.A.2
Formica, M.A.3
Cox, C.4
Walsh, E.E.5
-
46
-
-
84901800059
-
Respiratory syncytial virus and other respiratory viral infections in older adults with moderate to severe influenza-like illness
-
Falsey, A.R., McElhaney, J.E., Beran, J., van Essen, G.A., Duval, X., Esen, M., Galtier, F., Gervais, P., Hwang, S.J., Kremsner, P., Launay, O., Leroux-Roels, G., McNeil, S.A., Nowakowski, A., Richardus, J.H., Ruiz-Palacios, G., St Rose, S., Devaster, J.M., Oostvogels, L., Durviaux, S., Taylor, S., Respiratory syncytial virus and other respiratory viral infections in older adults with moderate to severe influenza-like illness. J. Infect. Dis. 209 (2014), 1873–1881.
-
(2014)
J. Infect. Dis.
, vol.209
, pp. 1873-1881
-
-
Falsey, A.R.1
McElhaney, J.E.2
Beran, J.3
van Essen, G.A.4
Duval, X.5
Esen, M.6
Galtier, F.7
Gervais, P.8
Hwang, S.J.9
Kremsner, P.10
Launay, O.11
Leroux-Roels, G.12
McNeil, S.A.13
Nowakowski, A.14
Richardus, J.H.15
Ruiz-Palacios, G.16
St Rose, S.17
Devaster, J.M.18
Oostvogels, L.19
Durviaux, S.20
Taylor, S.21
more..
-
47
-
-
84887492222
-
Treatment with interferon-alpha2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques
-
Falzarano, D., de Wit, E., Rasmussen, A.L., Feldmann, F., Okumura, A., Scott, D.P., Brining, D., Bushmaker, T., Martellaro, C., Baseler, L., Benecke, A.G., Katze, M.G., Munster, V.J., Feldmann, H., Treatment with interferon-alpha2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques. Nat. Med. 19 (2013), 1313–1317.
-
(2013)
Nat. Med.
, vol.19
, pp. 1313-1317
-
-
Falzarano, D.1
de Wit, E.2
Rasmussen, A.L.3
Feldmann, F.4
Okumura, A.5
Scott, D.P.6
Brining, D.7
Bushmaker, T.8
Martellaro, C.9
Baseler, L.10
Benecke, A.G.11
Katze, M.G.12
Munster, V.J.13
Feldmann, H.14
-
48
-
-
85063008890
-
Phase 2b study of pimodivir (JNJ-63623872) as monotherapy or in combination with oseltamivir for treatment of acute uncomplicated seasonal influenza A: TOPAZ trial
-
Finberg, R.W., Lanno, R., Anderson, D., Fleischhackl, R., van Duijnhoven, W., Kauffman, R.S., Kosoglou, T., Vingerhoets, J., Leopold, L., Phase 2b study of pimodivir (JNJ-63623872) as monotherapy or in combination with oseltamivir for treatment of acute uncomplicated seasonal influenza A: TOPAZ trial. J. Infect. Dis. 219:7 (2019 Mar 15), 1026–1034.
-
(2019)
J. Infect. Dis.
, vol.219
, Issue.7
, pp. 1026-1034
-
-
Finberg, R.W.1
Lanno, R.2
Anderson, D.3
Fleischhackl, R.4
van Duijnhoven, W.5
Kauffman, R.S.6
Kosoglou, T.7
Vingerhoets, J.8
Leopold, L.9
-
49
-
-
79956017135
-
Computational design of proteins targeting the conserved stem region of influenza hemagglutinin
-
Fleishman, S.J., Whitehead, T.A., Ekiert, D.C., Dreyfus, C., Corn, J.E., Strauch, E.M., Wilson, I.A., Baker, D., Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science 332 (2011), 816–821.
-
(2011)
Science
, vol.332
, pp. 816-821
-
-
Fleishman, S.J.1
Whitehead, T.A.2
Ekiert, D.C.3
Dreyfus, C.4
Corn, J.E.5
Strauch, E.M.6
Wilson, I.A.7
Baker, D.8
-
50
-
-
85061036083
-
Combination treatment with the cap-dependent endonuclease inhibitor baloxavir marboxil and a neuraminidase inhibitor in a mouse model of influenza A virus infection
-
Fukao, K., Noshi, T., Yamamoto, A., Kitano, M., Ando, Y., Noda, T., Baba, K., Matsumoto, K., Higuchi, N., Ikeda, M., Shishido, T., Naito, A., Combination treatment with the cap-dependent endonuclease inhibitor baloxavir marboxil and a neuraminidase inhibitor in a mouse model of influenza A virus infection. J. Antimicrob. Chemother. 74 (2019), 654–662.
-
(2019)
J. Antimicrob. Chemother.
, vol.74
, pp. 654-662
-
-
Fukao, K.1
Noshi, T.2
Yamamoto, A.3
Kitano, M.4
Ando, Y.5
Noda, T.6
Baba, K.7
Matsumoto, K.8
Higuchi, N.9
Ikeda, M.10
Shishido, T.11
Naito, A.12
-
51
-
-
84885448756
-
Favipiravir (T-705), a novel viral RNA polymerase inhibitor
-
Furuta, Y., Gowen, B.B., Takahashi, K., Shiraki, K., Smee, D.F., Barnard, D.L., Favipiravir (T-705), a novel viral RNA polymerase inhibitor. Antivir. Res. 100 (2013), 446–454.
-
(2013)
Antivir. Res.
, vol.100
, pp. 446-454
-
-
Furuta, Y.1
Gowen, B.B.2
Takahashi, K.3
Shiraki, K.4
Smee, D.F.5
Barnard, D.L.6
-
52
-
-
45949089501
-
A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation
-
Gaggar, A., Jackson, P.L., Noerager, B.D., O'Reilly, P.J., McQuaid, D.B., Rowe, S.M., Clancy, J.P., Blalock, J.E., A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation. J. Immunol. 180 (2008), 5662–5669.
-
(2008)
J. Immunol.
, vol.180
, pp. 5662-5669
-
-
Gaggar, A.1
Jackson, P.L.2
Noerager, B.D.3
O'Reilly, P.J.4
McQuaid, D.B.5
Rowe, S.M.6
Clancy, J.P.7
Blalock, J.E.8
-
53
-
-
85064133090
-
Efficacy and safety of nitazoxanide in addition to standard of care for the treatment of severe acute respiratory illness
-
[Epub ahead of print]
-
Gamino-Arroyo, A.E., Guerrero, M.L., McCarthy, S., Ramirez-Venegas, A., Llamosas-Gallardo, B., Galindo-Fraga, A., Moreno-Espinosa, S., Roldan-Aragon, Y., Araujo-Melendez, J., Hunsberger, S., Ibarra-Gonzalez, V., Martinez-Lopez, J., Garcia-Andrade, L.A., Kapushoc, H., Holley, H.P. Jr., Smolskis, M.C., Ruiz-Palacios, G.M., Beigel, J.H., Mexico Emerging Infectious Diseases Clinical Research, N. Efficacy and safety of nitazoxanide in addition to standard of care for the treatment of severe acute respiratory illness. Clin. Infect. Dis., 2019 Feb 7, 10.1093/cid/ciz100 [Epub ahead of print].
-
(2019)
Clin. Infect. Dis.
-
-
Gamino-Arroyo, A.E.1
Guerrero, M.L.2
McCarthy, S.3
Ramirez-Venegas, A.4
Llamosas-Gallardo, B.5
Galindo-Fraga, A.6
Moreno-Espinosa, S.7
Roldan-Aragon, Y.8
Araujo-Melendez, J.9
Hunsberger, S.10
Ibarra-Gonzalez, V.11
Martinez-Lopez, J.12
Garcia-Andrade, L.A.13
Kapushoc, H.14
Holley, H.P.15
Smolskis, M.C.16
Ruiz-Palacios, G.M.17
Beigel, J.H.18
-
54
-
-
85056226781
-
Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016
-
Global Burden of Disease Collaborators, Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Infect. Dis. 18 (2018), 1191–1210.
-
(2018)
Lancet Infect. Dis.
, vol.18
, pp. 1191-1210
-
-
Global Burden of Disease Collaborators1
-
55
-
-
79958117181
-
Pharmacokinetics of oseltamivir in breast milk and maternal plasma
-
Greer, L.G., Leff, R.D., Rogers, V.L., Roberts, S.W., McCracken, G.H. Jr., Wendel, G.D. Jr., Sheffield, J.S., Pharmacokinetics of oseltamivir in breast milk and maternal plasma. Am. J. Obstet. Gynecol. 204 (2011), 524 e521–524.
-
(2011)
Am. J. Obstet. Gynecol.
, vol.204
, pp. 524 e521-524
-
-
Greer, L.G.1
Leff, R.D.2
Rogers, V.L.3
Roberts, S.W.4
McCracken, G.H.5
Wendel, G.D.6
Sheffield, J.S.7
-
56
-
-
85027542792
-
Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2015-2016
-
Gubareva, L.V., Besselaar, T.G., Daniels, R.S., Fry, A., Gregory, V., Huang, W., Hurt, A.C., Jorquera, P.A., Lackenby, A., Leang, S.K., Lo, J., Pereyaslov, D., Rebelo-de-Andrade, H., Siqueira, M.M., Takashita, E., Odagiri, T., Wang, D., Zhang, W., Meijer, A., Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2015-2016. Antivir. Res. 146 (2017), 12–20.
-
(2017)
Antivir. Res.
, vol.146
, pp. 12-20
-
-
Gubareva, L.V.1
Besselaar, T.G.2
Daniels, R.S.3
Fry, A.4
Gregory, V.5
Huang, W.6
Hurt, A.C.7
Jorquera, P.A.8
Lackenby, A.9
Leang, S.K.10
Lo, J.11
Pereyaslov, D.12
Rebelo-de-Andrade, H.13
Siqueira, M.M.14
Takashita, E.15
Odagiri, T.16
Wang, D.17
Zhang, W.18
Meijer, A.19
-
57
-
-
85060397022
-
Assessing baloxavir susceptibility of influenza viruses circulating in the United States during the 2016/17 and 2017/18 seasons
-
Gubareva, L.V., Mishin, V.P., Patel, M.C., Chesnokov, A., Nguyen, H.T., De La Cruz, J., Spencer, S., Campbell, A.P., Sinner, M., Reid, H., Garten, R., Katz, J.M., Fry, A.M., Barnes, J., Wentworth, D.E., Assessing baloxavir susceptibility of influenza viruses circulating in the United States during the 2016/17 and 2017/18 seasons. Euro Surveill., 24, 2019.
-
(2019)
Euro Surveill.
, vol.24
-
-
Gubareva, L.V.1
Mishin, V.P.2
Patel, M.C.3
Chesnokov, A.4
Nguyen, H.T.5
De La Cruz, J.6
Spencer, S.7
Campbell, A.P.8
Sinner, M.9
Reid, H.10
Garten, R.11
Katz, J.M.12
Fry, A.M.13
Barnes, J.14
Wentworth, D.E.15
-
58
-
-
84966460100
-
Preclinical pharmacokinetics of MHAA4549A, a human monoclonal antibody to influenza A virus, and the prediction of its efficacious clinical dose for the treatment of patients hospitalized with influenza A
-
Gupta, P., Kamath, A.V., Park, S., Chiu, H., Lutman, J., Maia, M., Tan, M.-W., Xu, M., Swem, L., Deng, R., Preclinical pharmacokinetics of MHAA4549A, a human monoclonal antibody to influenza A virus, and the prediction of its efficacious clinical dose for the treatment of patients hospitalized with influenza A. mAbs 8 (2016), 991–997.
-
(2016)
mAbs
, vol.8
, pp. 991-997
-
-
Gupta, P.1
Kamath, A.V.2
Park, S.3
Chiu, H.4
Lutman, J.5
Maia, M.6
Tan, M.-W.7
Xu, M.8
Swem, L.9
Deng, R.10
-
59
-
-
84904740878
-
Effect of nitazoxanide in adults and adolescents with acute uncomplicated influenza: a double-blind, randomised, placebo-controlled, phase 2b/3 trial
-
Haffizulla, J., Hartman, A., Hoppers, M., Resnick, H., Samudrala, S., Ginocchio, C., Bardin, M., Rossignol, J.F., Group, U.S.N.I.C.S. Effect of nitazoxanide in adults and adolescents with acute uncomplicated influenza: a double-blind, randomised, placebo-controlled, phase 2b/3 trial. Lancet Infect. Dis. 14 (2014), 609–618.
-
(2014)
Lancet Infect. Dis.
, vol.14
, pp. 609-618
-
-
Haffizulla, J.1
Hartman, A.2
Hoppers, M.3
Resnick, H.4
Samudrala, S.5
Ginocchio, C.6
Bardin, M.7
Rossignol, J.F.8
-
60
-
-
59749095702
-
The burden of respiratory syncytial virus infection in young children
-
Hall, C.B., Weinberg, G.A., Iwane, M.K., Blumkin, A.K., Edwards, K.M., Staat, M.A., Auinger, P., Griffin, M.R., Poehling, K.A., Erdman, D., Grijalva, C.G., Zhu, Y., Szilagyi, P., The burden of respiratory syncytial virus infection in young children. N. Engl. J. Med. 360 (2009), 588–598.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 588-598
-
-
Hall, C.B.1
Weinberg, G.A.2
Iwane, M.K.3
Blumkin, A.K.4
Edwards, K.M.5
Staat, M.A.6
Auinger, P.7
Griffin, M.R.8
Poehling, K.A.9
Erdman, D.10
Grijalva, C.G.11
Zhu, Y.12
Szilagyi, P.13
-
61
-
-
84894028391
-
Interferon-beta and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays
-
Hart, B.J., Dyall, J., Postnikova, E., Zhou, H., Kindrachuk, J., Johnson, R.F., Olinger, G.G. Jr., Frieman, M.B., Holbrook, M.R., Jahrling, P.B., Hensley, L., Interferon-beta and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays. J. Gen. Virol. 95 (2014), 571–577.
-
(2014)
J. Gen. Virol.
, vol.95
, pp. 571-577
-
-
Hart, B.J.1
Dyall, J.2
Postnikova, E.3
Zhou, H.4
Kindrachuk, J.5
Johnson, R.F.6
Olinger, G.G.7
Frieman, M.B.8
Holbrook, M.R.9
Jahrling, P.B.10
Hensley, L.11
-
62
-
-
85053212099
-
Baloxavir marboxil for uncomplicated influenza in adults and adolescents
-
Hayden, F.G., Sugaya, N., Hirotsu, N., Lee, N., de Jong, M.D., Hurt, A.C., Ishida, T., Sekino, H., Yamada, K., Portsmouth, S., Kawaguchi, K., Shishido, T., Arai, M., Tsuchiya, K., Uehara, T., Watanabe, A., Baloxavir Marboxil Investigators, G., Baloxavir marboxil for uncomplicated influenza in adults and adolescents. N. Engl. J. Med. 379 (2018), 913–923.
-
(2018)
N. Engl. J. Med.
, vol.379
, pp. 913-923
-
-
Hayden, F.G.1
Sugaya, N.2
Hirotsu, N.3
Lee, N.4
de Jong, M.D.5
Hurt, A.C.6
Ishida, T.7
Sekino, H.8
Yamada, K.9
Portsmouth, S.10
Kawaguchi, K.11
Shishido, T.12
Arai, M.13
Tsuchiya, K.14
Uehara, T.15
Watanabe, A.16
Baloxavir Marboxil Investigators, G.17
-
63
-
-
85059640945
-
Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: results from a randomized, double-blind, phase-2, placebo-controlled study
-
Hershberger, E., Sloan, S., Narayan, K., Hay, C.A., Smith, P., Engler, F., Jeeninga, R., Smits, S., Trevejo, J., Shriver, Z., Oldach, D., Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: results from a randomized, double-blind, phase-2, placebo-controlled study. EBioMedicine 40 (2019 Feb), 574–582.
-
(2019)
EBioMedicine
, vol.40
, pp. 574-582
-
-
Hershberger, E.1
Sloan, S.2
Narayan, K.3
Hay, C.A.4
Smith, P.5
Engler, F.6
Jeeninga, R.7
Smits, S.8
Trevejo, J.9
Shriver, Z.10
Oldach, D.11
-
64
-
-
85044290633
-
The role of adjuvant immunomodulatory agents for treatment of severe influenza
-
Hui, D.S., Lee, N., Chan, P.K., Beigel, J.H., The role of adjuvant immunomodulatory agents for treatment of severe influenza. Antivir. Res. 150 (2018), 202–216.
-
(2018)
Antivir. Res.
, vol.150
, pp. 202-216
-
-
Hui, D.S.1
Lee, N.2
Chan, P.K.3
Beigel, J.H.4
-
65
-
-
79951821842
-
Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection
-
Hung, I.F., To, K.K., Lee, C.K., Lee, K.L., Chan, K., Yan, W.W., Liu, R., Watt, C.L., Chan, W.M., Lai, K.Y., Koo, C.K., Buckley, T., Chow, F.L., Wong, K.K., Chan, H.S., Ching, C.K., Tang, B.S., Lau, C.C., Li, I.W., Liu, S.H., Chan, K.H., Lin, C.K., Yuen, K.Y., Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection. Clin. Infect. Dis. 52 (2011), 447–456.
-
(2011)
Clin. Infect. Dis.
, vol.52
, pp. 447-456
-
-
Hung, I.F.1
To, K.K.2
Lee, C.K.3
Lee, K.L.4
Chan, K.5
Yan, W.W.6
Liu, R.7
Watt, C.L.8
Chan, W.M.9
Lai, K.Y.10
Koo, C.K.11
Buckley, T.12
Chow, F.L.13
Wong, K.K.14
Chan, H.S.15
Ching, C.K.16
Tang, B.S.17
Lau, C.C.18
Li, I.W.19
Liu, S.H.20
Chan, K.H.21
Lin, C.K.22
Yuen, K.Y.23
more..
-
66
-
-
85019156178
-
Efficacy of clarithromycin-naproxen-oseltamivir combination in the treatment of patients hospitalized for influenza A(H3N2) infection: an open-label randomized, controlled, phase IIb/III trial
-
Hung, I.F.N., To, K.K.W., Chan, J.F.W., Cheng, V.C.C., Liu, K.S.H., Tam, A., Chan, T.C., Zhang, A.J., Li, P., Wong, T.L., Zhang, R., Cheung, M.K.S., Leung, W., Lau, J.Y.N., Fok, M., Chen, H., Chan, K.H., Yuen, K.Y., Efficacy of clarithromycin-naproxen-oseltamivir combination in the treatment of patients hospitalized for influenza A(H3N2) infection: an open-label randomized, controlled, phase IIb/III trial. Chest 151 (2017), 1069–1080.
-
(2017)
Chest
, vol.151
, pp. 1069-1080
-
-
Hung, I.F.N.1
To, K.K.W.2
Chan, J.F.W.3
Cheng, V.C.C.4
Liu, K.S.H.5
Tam, A.6
Chan, T.C.7
Zhang, A.J.8
Li, P.9
Wong, T.L.10
Zhang, R.11
Cheung, M.K.S.12
Leung, W.13
Lau, J.Y.N.14
Fok, M.15
Chen, H.16
Chan, K.H.17
Yuen, K.Y.18
-
67
-
-
84877920290
-
Hyperimmune IV immunoglobulin treatment: a multicenter double-blind randomized controlled trial for patients with severe 2009 influenza A(H1N1) infection
-
Hung, I.F.N., To, K.K.W., Lee, C.K., Lee, K.L., Yan, W.W., Chan, K., Chan, W.M., Ngai, C.W., Law, K.I., Chow, F.L., Liu, R., Lai, K.Y., Lau, C.C.Y., Liu, S.H., Chan, K.H., Lin, C.K., Yuen, K.Y., Hyperimmune IV immunoglobulin treatment: a multicenter double-blind randomized controlled trial for patients with severe 2009 influenza A(H1N1) infection. Chest 144 (2013), 464–473.
-
(2013)
Chest
, vol.144
, pp. 464-473
-
-
Hung, I.F.N.1
To, K.K.W.2
Lee, C.K.3
Lee, K.L.4
Yan, W.W.5
Chan, K.6
Chan, W.M.7
Ngai, C.W.8
Law, K.I.9
Chow, F.L.10
Liu, R.11
Lai, K.Y.12
Lau, C.C.Y.13
Liu, S.H.14
Chan, K.H.15
Lin, C.K.16
Yuen, K.Y.17
-
68
-
-
85064132385
-
Options IX
-
Chicago. Abstract LBP-17
-
Ison, M., Options IX. Chicago. Abstract LBP-17, 2016.
-
(2016)
-
-
Ison, M.1
-
69
-
-
85044182212
-
Improving delivery of early treatment to influenza-infected patients
-
Ison, M.G., Improving delivery of early treatment to influenza-infected patients. Clin. Infect. Dis. 66 (2017), 1042–1044.
-
(2017)
Clin. Infect. Dis.
, vol.66
, pp. 1042-1044
-
-
Ison, M.G.1
-
70
-
-
77951887472
-
End points for testing influenza antiviral treatments for patients at high risk of severe and life-threatening disease
-
Ison, M.G., de Jong, M.D., Gilligan, K.J., Higgs, E.S., Pavia, A.T., Pierson, J., Hayden, F.G., End points for testing influenza antiviral treatments for patients at high risk of severe and life-threatening disease. J. Infect. Dis. 201 (2010), 1654–1662.
-
(2010)
J. Infect. Dis.
, vol.201
, pp. 1654-1662
-
-
Ison, M.G.1
de Jong, M.D.2
Gilligan, K.J.3
Higgs, E.S.4
Pavia, A.T.5
Pierson, J.6
Hayden, F.G.7
-
71
-
-
85063009815
-
LB16. Phase 3 trial of baloxavir marboxil in high-risk influenza patients (CAPSTONE-2 study)
-
Ison, M.G., Portsmouth, S., Yoshida, Y., Shishido, T., Hayden, F., Uehara, T., LB16. Phase 3 trial of baloxavir marboxil in high-risk influenza patients (CAPSTONE-2 study). Open Forum Infect. Dis. 5 (2018), S764–S765.
-
(2018)
Open Forum Infect. Dis.
, vol.5
, pp. S764-S765
-
-
Ison, M.G.1
Portsmouth, S.2
Yoshida, Y.3
Shishido, T.4
Hayden, F.5
Uehara, T.6
-
72
-
-
85046436614
-
Identification of the I38T PA substitution as a resistance marker for next-generation influenza virus endonuclease inhibitors
-
Jones, J.C., Kumar, G., Barman, S., Najera, I., White, S.W., Webby, R.J., Govorkova, E.A., Identification of the I38T PA substitution as a resistance marker for next-generation influenza virus endonuclease inhibitors. mBio, 9, 2018.
-
(2018)
mBio
, vol.9
-
-
Jones, J.C.1
Kumar, G.2
Barman, S.3
Najera, I.4
White, S.W.5
Webby, R.J.6
Govorkova, E.A.7
-
73
-
-
84983314482
-
A novel endonuclease inhibitor exhibits broad-spectrum anti-influenza virus activity in vitro
-
Jones, J.C., Marathe, B.M., Lerner, C., Kreis, L., Gasser, R., Pascua, P.N., Najera, I., Govorkova, E.A., A novel endonuclease inhibitor exhibits broad-spectrum anti-influenza virus activity in vitro. Antimicrob. Agents Chemother. 60 (2016), 5504–5514.
-
(2016)
Antimicrob. Agents Chemother.
, vol.60
, pp. 5504-5514
-
-
Jones, J.C.1
Marathe, B.M.2
Lerner, C.3
Kreis, L.4
Gasser, R.5
Pascua, P.N.6
Najera, I.7
Govorkova, E.A.8
-
74
-
-
85018868773
-
Inhibitors of influenza virus polymerase acidic (PA) endonuclease: contemporary developments and perspectives
-
Ju, H., Zhang, J., Huang, B., Kang, D., Huang, B., Liu, X., Zhan, P., Inhibitors of influenza virus polymerase acidic (PA) endonuclease: contemporary developments and perspectives. J. Med. Chem. 60 (2017), 3533–3551.
-
(2017)
J. Med. Chem.
, vol.60
, pp. 3533-3551
-
-
Ju, H.1
Zhang, J.2
Huang, B.3
Kang, D.4
Huang, B.5
Liu, X.6
Zhan, P.7
-
75
-
-
85009380300
-
Structural basis of influenza virus fusion inhibition by the antiviral drug arbidol
-
Kadam, R.U., Wilson, I.A., Structural basis of influenza virus fusion inhibition by the antiviral drug arbidol. Proc. Natl. Acad. Sci. U. S. A. 114 (2017), 206–214.
-
(2017)
Proc. Natl. Acad. Sci. U. S. A.
, vol.114
, pp. 206-214
-
-
Kadam, R.U.1
Wilson, I.A.2
-
76
-
-
72049128868
-
Clinical effectiveness of oseltamivir and zanamivir for treatment of influenza A virus subtype H1N1 with the H274Y mutation: a Japanese, multicenter study of the 2007-2008 and 2008-2009 influenza seasons
-
Kawai, N., Ikematsu, H., Hirotsu, N., Maeda, T., Kawashima, T., Tanaka, O., Yamauchi, S., Kawamura, K., Matsuura, S., Nishimura, M., Iwaki, N., Kashiwagi, S., Clinical effectiveness of oseltamivir and zanamivir for treatment of influenza A virus subtype H1N1 with the H274Y mutation: a Japanese, multicenter study of the 2007-2008 and 2008-2009 influenza seasons. Clin. Infect. Dis. 49 (2009), 1828–1835.
-
(2009)
Clin. Infect. Dis.
, vol.49
, pp. 1828-1835
-
-
Kawai, N.1
Ikematsu, H.2
Hirotsu, N.3
Maeda, T.4
Kawashima, T.5
Tanaka, O.6
Yamauchi, S.7
Kawamura, K.8
Matsuura, S.9
Nishimura, M.10
Iwaki, N.11
Kashiwagi, S.12
-
77
-
-
84913590251
-
Respiratory syncytial virus human experimental infection model: provenance, production, and sequence of low-passaged memphis-37 challenge virus
-
Kim, Y.I., DeVincenzo, J.P., Jones, B.G., Rudraraju, R., Harrison, L., Meyers, R., Cehelsky, J., Alvarez, R., Hurwitz, J.L., Respiratory syncytial virus human experimental infection model: provenance, production, and sequence of low-passaged memphis-37 challenge virus. PLoS One, 9, 2014, e113100.
-
(2014)
PLoS One
, vol.9
-
-
Kim, Y.I.1
DeVincenzo, J.P.2
Jones, B.G.3
Rudraraju, R.4
Harrison, L.5
Meyers, R.6
Cehelsky, J.7
Alvarez, R.8
Hurwitz, J.L.9
-
78
-
-
85033230992
-
The antiviral effects of RSV fusion inhibitor, MDT-637, on clinical isolates, vs its achievable concentrations in the human respiratory tract and comparison to ribavirin
-
Kim, Y.I., Pareek, R., Murphy, R., Harrison, L., Farrell, E., Cook, R., DeVincenzo, J., The antiviral effects of RSV fusion inhibitor, MDT-637, on clinical isolates, vs its achievable concentrations in the human respiratory tract and comparison to ribavirin. Influenza Other Respir Viruses 11 (2017), 525–530.
-
(2017)
Influenza Other Respir Viruses
, vol.11
, pp. 525-530
-
-
Kim, Y.I.1
Pareek, R.2
Murphy, R.3
Harrison, L.4
Farrell, E.5
Cook, R.6
DeVincenzo, J.7
-
79
-
-
85064116849
-
IDWeek 2016
-
New Orleans. Abstract 638
-
King, J., IDWeek 2016. New Orleans. Abstract 638, 2016.
-
(2016)
-
-
King, J.1
-
80
-
-
85055907907
-
Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin
-
Laursen, N.S., Friesen, R.H.E., Zhu, X., Jongeneelen, M., Blokland, S., Vermond, J., van Eijgen, A., Tang, C., van Diepen, H., Obmolova, G., van der Neut Kolfschoten, M., Zuijdgeest, D., Straetemans, R., Hoffman, R.M.B., Nieusma, T., Pallesen, J., Turner, H.L., Bernard, S.M., Ward, A.B., Luo, J., Poon, L.L.M., Tretiakova, A.P., Wilson, J.M., Limberis, M.P., Vogels, R., Brandenburg, B., Kolkman, J.A., Wilson, I.A., Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science 362 (2018), 598–602.
-
(2018)
Science
, vol.362
, pp. 598-602
-
-
Laursen, N.S.1
Friesen, R.H.E.2
Zhu, X.3
Jongeneelen, M.4
Blokland, S.5
Vermond, J.6
van Eijgen, A.7
Tang, C.8
van Diepen, H.9
Obmolova, G.10
van der Neut Kolfschoten, M.11
Zuijdgeest, D.12
Straetemans, R.13
Hoffman, R.M.B.14
Nieusma, T.15
Pallesen, J.16
Turner, H.L.17
Bernard, S.M.18
Ward, A.B.19
Luo, J.20
Poon, L.L.M.21
Tretiakova, A.P.22
Wilson, J.M.23
Limberis, M.P.24
Vogels, R.25
Brandenburg, B.26
Kolkman, J.A.27
Wilson, I.A.28
more..
-
81
-
-
85019645225
-
Anti-inflammatory effects of adjunctive macrolide treatment in adults hospitalized with influenza: a randomized controlled trial
-
Lee, N., Wong, C.K., Chan, M.C.W., Yeung, E.S.L., Tam, W.W.S., Tsang, O.T.Y., Choi, K.W., Chan, P.K.S., Kwok, A., Lui, G.C.Y., Leung, W.S., Yung, I.M.H., Wong, R.Y.K., Cheung, C.S.K., Hui, D.S.C., Anti-inflammatory effects of adjunctive macrolide treatment in adults hospitalized with influenza: a randomized controlled trial. Antivir. Res. 144 (2017), 48–56.
-
(2017)
Antivir. Res.
, vol.144
, pp. 48-56
-
-
Lee, N.1
Wong, C.K.2
Chan, M.C.W.3
Yeung, E.S.L.4
Tam, W.W.S.5
Tsang, O.T.Y.6
Choi, K.W.7
Chan, P.K.S.8
Kwok, A.9
Lui, G.C.Y.10
Leung, W.S.11
Yung, I.M.H.12
Wong, R.Y.K.13
Cheung, C.S.K.14
Hui, D.S.C.15
-
82
-
-
84956678939
-
Virus susceptibility and clinical effectiveness of anti-influenza drugs during the 2010-2011 influenza season in Russia
-
Leneva, I.A., Burtseva, E.I., Yatsyshina, S.B., Fedyakina, I.T., Kirillova, E.S., Selkova, E.P., Osipova, E., Maleev, V.V., Virus susceptibility and clinical effectiveness of anti-influenza drugs during the 2010-2011 influenza season in Russia. Int. J. Infect. Dis. 43 (2016), 77–84.
-
(2016)
Int. J. Infect. Dis.
, vol.43
, pp. 77-84
-
-
Leneva, I.A.1
Burtseva, E.I.2
Yatsyshina, S.B.3
Fedyakina, I.T.4
Kirillova, E.S.5
Selkova, E.P.6
Osipova, E.7
Maleev, V.V.8
-
83
-
-
85058602387
-
Type I interferons: distinct biological activities and current applications for viral infection
-
Li, S.F., Gong, M.J., Zhao, F.R., Shao, J.J., Xie, Y.L., Zhang, Y.G., Chang, H.Y., Type I interferons: distinct biological activities and current applications for viral infection. Cell. Physiol. Biochem. 51 (2018), 2377–2396.
-
(2018)
Cell. Physiol. Biochem.
, vol.51
, pp. 2377-2396
-
-
Li, S.F.1
Gong, M.J.2
Zhao, F.R.3
Shao, J.J.4
Xie, Y.L.5
Zhang, Y.G.6
Chang, H.Y.7
-
84
-
-
85040699532
-
Five years of monitoring for the emergence of oseltamivir resistance in patients with influenza A infections in the influenza resistance information study
-
Lina, B., Boucher, C., Osterhaus, A., Monto, A.S., Schutten, M., Whitley, R.J., Nguyen-Van-Tam, J.S., Five years of monitoring for the emergence of oseltamivir resistance in patients with influenza A infections in the influenza resistance information study. Influenza Other Respir Viruses 12 (2018), 267–278.
-
(2018)
Influenza Other Respir Viruses
, vol.12
, pp. 267-278
-
-
Lina, B.1
Boucher, C.2
Osterhaus, A.3
Monto, A.S.4
Schutten, M.5
Whitley, R.J.6
Nguyen-Van-Tam, J.S.7
-
85
-
-
0029958486
-
Pharmacokinetics of inhaled drugs
-
Lipworth, B.J., Pharmacokinetics of inhaled drugs. Br. J. Clin. Pharmacol. 42 (1996), 697–705.
-
(1996)
Br. J. Clin. Pharmacol.
, vol.42
, pp. 697-705
-
-
Lipworth, B.J.1
-
86
-
-
85014764670
-
GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses
-
Lo, M.K., Jordan, R., Arvey, A., Sudhamsu, J., Shrivastava-Ranjan, P., Hotard, A.L., Flint, M., McMullan, L.K., Siegel, D., Clarke, M.O., Mackman, R.L., Hui, H.C., Perron, M., Ray, A.S., Cihlar, T., Nichol, S.T., Spiropoulou, C.F., GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses. Sci. Rep., 7, 2017, 43395.
-
(2017)
Sci. Rep.
, vol.7
, pp. 43395
-
-
Lo, M.K.1
Jordan, R.2
Arvey, A.3
Sudhamsu, J.4
Shrivastava-Ranjan, P.5
Hotard, A.L.6
Flint, M.7
McMullan, L.K.8
Siegel, D.9
Clarke, M.O.10
Mackman, R.L.11
Hui, H.C.12
Perron, M.13
Ray, A.S.14
Cihlar, T.15
Nichol, S.T.16
Spiropoulou, C.F.17
-
87
-
-
84973153410
-
Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo
-
326ra321
-
Luke, T., Wu, H., Zhao, J., Channappanavar, R., Coleman, C.M., Jiao, J.A., Matsushita, H., Liu, Y., Postnikova, E.N., Ork, B.L., Glenn, G., Flyer, D., Defang, G., Raviprakash, K., Kochel, T., Wang, J., Nie, W., Smith, G., Hensley, L.E., Olinger, G.G., Kuhn, J.H., Holbrook, M.R., Johnson, R.F., Perlman, S., Sullivan, E., Frieman, M.B., Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo. Sci. Transl. Med., 8, 2016 326ra321.
-
(2016)
Sci. Transl. Med.
, vol.8
-
-
Luke, T.1
Wu, H.2
Zhao, J.3
Channappanavar, R.4
Coleman, C.M.5
Jiao, J.A.6
Matsushita, H.7
Liu, Y.8
Postnikova, E.N.9
Ork, B.L.10
Glenn, G.11
Flyer, D.12
Defang, G.13
Raviprakash, K.14
Kochel, T.15
Wang, J.16
Nie, W.17
Smith, G.18
Hensley, L.E.19
Olinger, G.G.20
Kuhn, J.H.21
Holbrook, M.R.22
Johnson, R.F.23
Perlman, S.24
Sullivan, E.25
Frieman, M.B.26
more..
-
88
-
-
33750721332
-
Meta-analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?
-
Luke, T.C., Kilbane, E.M., Jackson, J.L., Hoffman, S.L., Meta-analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?. Ann. Intern. Med. 145 (2006), 599–609.
-
(2006)
Ann. Intern. Med.
, vol.145
, pp. 599-609
-
-
Luke, T.C.1
Kilbane, E.M.2
Jackson, J.L.3
Hoffman, S.L.4
-
89
-
-
85064136004
-
Antiviral effects, pharmacokinetics and safety of the respiratory syncytial virus fusion protein inhibitor, JNJ-53718678
-
IDWeek 2018 San Francisco, CA
-
Martinon-Torres, F., Rusch, S., Huntjens, D., Remmerie, B., Vingerhoets, J., McFadyen, K., Stevens, M., Antiviral effects, pharmacokinetics and safety of the respiratory syncytial virus fusion protein inhibitor, JNJ-53718678. RSV-infected Infants with Bronchiolitis, in the Phase 1b Study 53718678RSV1005, 2018, IDWeek 2018, San Francisco, CA.
-
(2018)
RSV-infected Infants with Bronchiolitis, in the Phase 1b Study 53718678RSV1005
-
-
Martinon-Torres, F.1
Rusch, S.2
Huntjens, D.3
Remmerie, B.4
Vingerhoets, J.5
McFadyen, K.6
Stevens, M.7
-
90
-
-
85009420566
-
Intravenous zanamivir or oral oseltamivir for hospitalised patients with influenza: an international, randomised, double-blind, double-dummy, phase 3 trial
-
Marty, F.M., Vidal-Puigserver, J., Clark, C., Gupta, S.K., Merino, E., Garot, D., Chapman, M.J., Jacobs, F., Rodriguez-Noriega, E., Husa, P., Shortino, D., Watson, H.A., Yates, P.J., Peppercorn, A.F., Intravenous zanamivir or oral oseltamivir for hospitalised patients with influenza: an international, randomised, double-blind, double-dummy, phase 3 trial. Lancet Respir. Med. 5 (2017), 135–146.
-
(2017)
Lancet Respir. Med.
, vol.5
, pp. 135-146
-
-
Marty, F.M.1
Vidal-Puigserver, J.2
Clark, C.3
Gupta, S.K.4
Merino, E.5
Garot, D.6
Chapman, M.J.7
Jacobs, F.8
Rodriguez-Noriega, E.9
Husa, P.10
Shortino, D.11
Watson, H.A.12
Yates, P.J.13
Peppercorn, A.F.14
-
91
-
-
85032467827
-
Phase 2 randomized trial of the safety and efficacy of MHAA4549A, a broadly neutralizing monoclonal antibody, in a human influenza a virus challenge model
-
McBride, J.M., Lim, J.J., Burgess, T., Deng, R., Derby, M.A., Maia, M., Horn, P., Siddiqui, O., Sheinson, D., Chen-Harris, H., Newton, E.M., Fillos, D., Nazzal, D., Rosenberger, C.M., Ohlson, M.B., Lambkin-Williams, R., Fathi, H., Harris, J.M., Tavel, J.A., Phase 2 randomized trial of the safety and efficacy of MHAA4549A, a broadly neutralizing monoclonal antibody, in a human influenza a virus challenge model. Antimicrob. Agents Chemother., 61, 2017, 17.
-
(2017)
Antimicrob. Agents Chemother.
, vol.61
, pp. 17
-
-
McBride, J.M.1
Lim, J.J.2
Burgess, T.3
Deng, R.4
Derby, M.A.5
Maia, M.6
Horn, P.7
Siddiqui, O.8
Sheinson, D.9
Chen-Harris, H.10
Newton, E.M.11
Fillos, D.12
Nazzal, D.13
Rosenberger, C.M.14
Ohlson, M.B.15
Lambkin-Williams, R.16
Fathi, H.17
Harris, J.M.18
Tavel, J.A.19
-
92
-
-
85035785809
-
Prevention and treatment of respiratory viral infections: presentations on antivirals, traditional therapies and host-directed interventions at the 5th ISIRV Antiviral Group conference
-
McKimm-Breschkin, J.L., Jiang, S., Hui, D.S., Beigel, J.H., Govorkova, E.A., Lee, N., Prevention and treatment of respiratory viral infections: presentations on antivirals, traditional therapies and host-directed interventions at the 5th ISIRV Antiviral Group conference. Antivir. Res. 149 (2018), 118–142.
-
(2018)
Antivir. Res.
, vol.149
, pp. 118-142
-
-
McKimm-Breschkin, J.L.1
Jiang, S.2
Hui, D.S.3
Beigel, J.H.4
Govorkova, E.A.5
Lee, N.6
-
93
-
-
84891808523
-
The natural history of influenza infection in the severely immunocompromised vs nonimmunocompromised hosts
-
Memoli, M.J., Athota, R., Reed, S., Czajkowski, L., Bristol, T., Proudfoot, K., Hagey, R., Voell, J., Fiorentino, C., Ademposi, A., Shoham, S., Taubenberger, J.K., The natural history of influenza infection in the severely immunocompromised vs nonimmunocompromised hosts. Clin. Infect. Dis. 58 (2014), 214–224.
-
(2014)
Clin. Infect. Dis.
, vol.58
, pp. 214-224
-
-
Memoli, M.J.1
Athota, R.2
Reed, S.3
Czajkowski, L.4
Bristol, T.5
Proudfoot, K.6
Hagey, R.7
Voell, J.8
Fiorentino, C.9
Ademposi, A.10
Shoham, S.11
Taubenberger, J.K.12
-
94
-
-
84949623850
-
A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
-
Menachery, V.D., Yount, B.L. Jr., Debbink, K., Agnihothram, S., Gralinski, L.E., Plante, J.A., Graham, R.L., Scobey, T., Ge, X.Y., Donaldson, E.F., Randell, S.H., Lanzavecchia, A., Marasco, W.A., Shi, Z.L., Baric, R.S., A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nat. Med. 21 (2015), 1508–1513.
-
(2015)
Nat. Med.
, vol.21
, pp. 1508-1513
-
-
Menachery, V.D.1
Yount, B.L.2
Debbink, K.3
Agnihothram, S.4
Gralinski, L.E.5
Plante, J.A.6
Graham, R.L.7
Scobey, T.8
Ge, X.Y.9
Donaldson, E.F.10
Randell, S.H.11
Lanzavecchia, A.12
Marasco, W.A.13
Shi, Z.L.14
Baric, R.S.15
-
95
-
-
84962487236
-
SARS-like WIV1-CoV poised for human emergence
-
Menachery, V.D., Yount, B.L. Jr., Sims, A.C., Debbink, K., Agnihothram, S.S., Gralinski, L.E., Graham, R.L., Scobey, T., Plante, J.A., Royal, S.R., Swanstrom, J., Sheahan, T.P., Pickles, R.J., Corti, D., Randell, S.H., Lanzavecchia, A., Marasco, W.A., Baric, R.S., SARS-like WIV1-CoV poised for human emergence. Proc. Natl. Acad. Sci. U. S. A. 113 (2016), 3048–3053.
-
(2016)
Proc. Natl. Acad. Sci. U. S. A.
, vol.113
, pp. 3048-3053
-
-
Menachery, V.D.1
Yount, B.L.2
Sims, A.C.3
Debbink, K.4
Agnihothram, S.S.5
Gralinski, L.E.6
Graham, R.L.7
Scobey, T.8
Plante, J.A.9
Royal, S.R.10
Swanstrom, J.11
Sheahan, T.P.12
Pickles, R.J.13
Corti, D.14
Randell, S.H.15
Lanzavecchia, A.16
Marasco, W.A.17
Baric, R.S.18
-
96
-
-
85050799094
-
A review of therapeutics in clinical development for respiratory syncytial virus and influenza in children
-
Nicholson, E.G., Munoz, F.M., A review of therapeutics in clinical development for respiratory syncytial virus and influenza in children. Clin. Ther. 40 (2018), 1268–1281.
-
(2018)
Clin. Ther.
, vol.40
, pp. 1268-1281
-
-
Nicholson, E.G.1
Munoz, F.M.2
-
97
-
-
85055754733
-
In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit
-
Noshi, T., Kitano, M., Taniguchi, K., Yamamoto, A., Omoto, S., Baba, K., Hashimoto, T., Ishida, K., Kushima, Y., Hattori, K., Kawai, M., Yoshida, R., Kobayashi, M., Yoshinaga, T., Sato, A., Okamatsu, M., Sakoda, Y., Kida, H., Shishido, T., Naito, A., In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Antivir. Res. 160 (2018), 109–117.
-
(2018)
Antivir. Res.
, vol.160
, pp. 109-117
-
-
Noshi, T.1
Kitano, M.2
Taniguchi, K.3
Yamamoto, A.4
Omoto, S.5
Baba, K.6
Hashimoto, T.7
Ishida, K.8
Kushima, Y.9
Hattori, K.10
Kawai, M.11
Yoshida, R.12
Kobayashi, M.13
Yoshinaga, T.14
Sato, A.15
Okamatsu, M.16
Sakoda, Y.17
Kida, H.18
Shishido, T.19
Naito, A.20
more..
-
98
-
-
84875196483
-
Pulmonary drug metabolism, clearance, and absorption
-
Olsson, B., Bondesson, E., Borgström, L., Edsbäcker, S., Eirefelt, S., Ekelund, K., Pulmonary drug metabolism, clearance, and absorption. Controlled Pulmonary Drug Delivery, 2011, 21–50.
-
(2011)
Controlled Pulmonary Drug Delivery
, pp. 21-50
-
-
Olsson, B.1
Bondesson, E.2
Borgström, L.3
Edsbäcker, S.4
Eirefelt, S.5
Ekelund, K.6
-
99
-
-
85049155088
-
Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil
-
Omoto, S., Speranzini, V., Hashimoto, T., Noshi, T., Yamaguchi, H., Kawai, M., Kawaguchi, K., Uehara, T., Shishido, T., Naito, A., Cusack, S., Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci. Rep., 8, 2018, 9633.
-
(2018)
Sci. Rep.
, vol.8
, pp. 9633
-
-
Omoto, S.1
Speranzini, V.2
Hashimoto, T.3
Noshi, T.4
Yamaguchi, H.5
Kawai, M.6
Kawaguchi, K.7
Uehara, T.8
Shishido, T.9
Naito, A.10
Cusack, S.11
-
100
-
-
84908285527
-
Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study
-
Omrani, A.S., Saad, M.M., Baig, K., Bahloul, A., Abdul-Matin, M., Alaidaroos, A.Y., Almakhlafi, G.A., Albarrak, M.M., Memish, Z.A., Albarrak, A.M., Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study. Lancet Infect. Dis. 14 (2014), 1090–1095.
-
(2014)
Lancet Infect. Dis.
, vol.14
, pp. 1090-1095
-
-
Omrani, A.S.1
Saad, M.M.2
Baig, K.3
Bahloul, A.4
Abdul-Matin, M.5
Alaidaroos, A.Y.6
Almakhlafi, G.A.7
Albarrak, M.M.8
Memish, Z.A.9
Albarrak, A.M.10
-
101
-
-
85026778439
-
Pathogenicity and peramivir efficacy in immunocompromised murine models of influenza B virus infection
-
Pascua, P.N.Q., Mostafa, H.H., Marathe, B.M., Vogel, P., Russell, C.J., Webby, R.J., Govorkova, E.A., Pathogenicity and peramivir efficacy in immunocompromised murine models of influenza B virus infection. Sci. Rep., 7, 2017, 7345.
-
(2017)
Sci. Rep.
, vol.7
, pp. 7345
-
-
Pascua, P.N.Q.1
Mostafa, H.H.2
Marathe, B.M.3
Vogel, P.4
Russell, C.J.5
Webby, R.J.6
Govorkova, E.A.7
-
102
-
-
85046417699
-
Serum high-mobility-group box 1 as a biomarker and a therapeutic target during respiratory virus infections
-
Patel, M.C., Shirey, K.A., Boukhvalova, M.S., Vogel, S.N., Blanco, J.C.G., Serum high-mobility-group box 1 as a biomarker and a therapeutic target during respiratory virus infections. mBio, 9, 2018.
-
(2018)
mBio
, vol.9
-
-
Patel, M.C.1
Shirey, K.A.2
Boukhvalova, M.S.3
Vogel, S.N.4
Blanco, J.C.G.5
-
103
-
-
18544379485
-
Comparison of a real-time reverse transcriptase PCR assay and a culture technique for quantitative assessment of viral load in children naturally infected with respiratory syncytial virus
-
Perkins, S.M., Webb, D.L., Torrance, S.A., El Saleeby, C., Harrison, L.M., Aitken, J.A., Patel, A., DeVincenzo, J.P., Comparison of a real-time reverse transcriptase PCR assay and a culture technique for quantitative assessment of viral load in children naturally infected with respiratory syncytial virus. J. Clin. Microbiol. 43 (2005), 2356–2362.
-
(2005)
J. Clin. Microbiol.
, vol.43
, pp. 2356-2362
-
-
Perkins, S.M.1
Webb, D.L.2
Torrance, S.A.3
El Saleeby, C.4
Harrison, L.M.5
Aitken, J.A.6
Patel, A.7
DeVincenzo, J.P.8
-
104
-
-
85010028170
-
TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection
-
Perrin-Cocon, L., Aublin-Gex, A., Sestito, S.E., Shirey, K.A., Patel, M.C., Andre, P., Blanco, J.C., Vogel, S.N., Peri, F., Lotteau, V., TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection. Sci. Rep., 7, 2017, 40791.
-
(2017)
Sci. Rep.
, vol.7
, pp. 40791
-
-
Perrin-Cocon, L.1
Aublin-Gex, A.2
Sestito, S.E.3
Shirey, K.A.4
Patel, M.C.5
Andre, P.6
Blanco, J.C.7
Vogel, S.N.8
Peri, F.9
Lotteau, V.10
-
105
-
-
84960157399
-
GS-5806 inhibits a broad range of respiratory syncytial virus clinical isolates by blocking the virus-cell fusion process
-
Perron, M., Stray, K., Kinkade, A., Theodore, D., Lee, G., Eisenberg, E., Sangi, M., Gilbert, B.E., Jordan, R., Piedra, P.A., Toms, G.L., Mackman, R., Cihlar, T., GS-5806 inhibits a broad range of respiratory syncytial virus clinical isolates by blocking the virus-cell fusion process. Antimicrob. Agents Chemother. 60 (2015), 1264–1273.
-
(2015)
Antimicrob. Agents Chemother.
, vol.60
, pp. 1264-1273
-
-
Perron, M.1
Stray, K.2
Kinkade, A.3
Theodore, D.4
Lee, G.5
Eisenberg, E.6
Sangi, M.7
Gilbert, B.E.8
Jordan, R.9
Piedra, P.A.10
Toms, G.L.11
Mackman, R.12
Cihlar, T.13
-
106
-
-
84955178842
-
Lopinavir and atazanavir in pregnancy: comparable infant outcomes, virological efficacies and preterm delivery rates
-
Perry, M.E., Taylor, G.P., Sabin, C.A., Conway, K., Flanagan, S., Dwyer, E., Stevenson, J., Mulka, L., McKendry, A., Williams, E., Barbour, A., Dermont, S., Roedling, S., Shah, R., Anderson, J., Rodgers, M., Wood, C., Sarner, L., Hay, P., Hawkins, D., deRuiter, A., Lopinavir and atazanavir in pregnancy: comparable infant outcomes, virological efficacies and preterm delivery rates. HIV Med. 17 (2016), 28–35.
-
(2016)
HIV Med.
, vol.17
, pp. 28-35
-
-
Perry, M.E.1
Taylor, G.P.2
Sabin, C.A.3
Conway, K.4
Flanagan, S.5
Dwyer, E.6
Stevenson, J.7
Mulka, L.8
McKendry, A.9
Williams, E.10
Barbour, A.11
Dermont, S.12
Roedling, S.13
Shah, R.14
Anderson, J.15
Rodgers, M.16
Wood, C.17
Sarner, L.18
Hay, P.19
Hawkins, D.20
deRuiter, A.21
more..
-
107
-
-
85019719832
-
Analysis of an ordinal endpoint for use in evaluating treatments for severe influenza requiring hospitalization
-
Peterson, R.L., Vock, D.M., Powers, J.H., Emery, S., Cruz, E.F., Hunsberger, S., Jain, M.K., Pett, S., Neaton, J.D., Analysis of an ordinal endpoint for use in evaluating treatments for severe influenza requiring hospitalization. Clin. Trials 14 (2017), 264–276.
-
(2017)
Clin. Trials
, vol.14
, pp. 264-276
-
-
Peterson, R.L.1
Vock, D.M.2
Powers, J.H.3
Emery, S.4
Cruz, E.F.5
Hunsberger, S.6
Jain, M.K.7
Pett, S.8
Neaton, J.D.9
-
108
-
-
85049772079
-
Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57
-
Piacentini, S., La Frazia, S., Riccio, A., Pedersen, J.Z., Topai, A., Nicolotti, O., Rossignol, J.F., Santoro, M.G., Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57. Sci. Rep., 8, 2018, 10425.
-
(2018)
Sci. Rep.
, vol.8
, pp. 10425
-
-
Piacentini, S.1
La Frazia, S.2
Riccio, A.3
Pedersen, J.Z.4
Topai, A.5
Nicolotti, O.6
Rossignol, J.F.7
Santoro, M.G.8
-
109
-
-
84933675709
-
A decoy peptide that disrupts TIRAP recruitment to TLRs is protective in a murine model of influenza
-
Piao, W., Shirey, K.A., Ru, L.W., Lai, W., Szmacinski, H., Snyder, G.A., Sundberg, E.J., Lakowicz, J.R., Vogel, S.N., Toshchakov, V.Y., A decoy peptide that disrupts TIRAP recruitment to TLRs is protective in a murine model of influenza. Cell Rep. 11 (2015), 1941–1952.
-
(2015)
Cell Rep.
, vol.11
, pp. 1941-1952
-
-
Piao, W.1
Shirey, K.A.2
Ru, L.W.3
Lai, W.4
Szmacinski, H.5
Snyder, G.A.6
Sundberg, E.J.7
Lakowicz, J.R.8
Vogel, S.N.9
Toshchakov, V.Y.10
-
110
-
-
85061588287
-
Repurposing of drugs as novel influenza inhibitors from clinical gene expression infection signatures
-
Pizzorno, A., Terrier, O., Nicolas de Lamballerie, C., Julien, T., Padey, B., Traversier, A., Roche, M., Hamelin, M.E., Rheaume, C., Croze, S., Escuret, V., Poissy, J., Lina, B., Legras-Lachuer, C., Textoris, J., Boivin, G., Rosa-Calatrava, M., Repurposing of drugs as novel influenza inhibitors from clinical gene expression infection signatures. Front. Immunol., 10, 2019, 60.
-
(2019)
Front. Immunol.
, vol.10
, pp. 60
-
-
Pizzorno, A.1
Terrier, O.2
Nicolas de Lamballerie, C.3
Julien, T.4
Padey, B.5
Traversier, A.6
Roche, M.7
Hamelin, M.E.8
Rheaume, C.9
Croze, S.10
Escuret, V.11
Poissy, J.12
Lina, B.13
Legras-Lachuer, C.14
Textoris, J.15
Boivin, G.16
Rosa-Calatrava, M.17
-
111
-
-
85020411021
-
Reliability, validity, and responsiveness of InFLUenza patient-reported outcome (FLU-PRO(c)) scores in influenza-positive patients
-
Powers, J.H. 3rd, Bacci, E.D., Guerrero, M.L., Leidy, N.K., Stringer, S., Kim, K., Memoli, M.J., Han, A., Fairchok, M.P., Chen, W.J., Arnold, J.C., Danaher, P.J., Lalani, T., Ridore, M., Burgess, T.H., Millar, E.V., Hernandez, A., Rodriguez-Zulueta, P., Smolskis, M.C., Ortega-Gallegos, H., Pett, S., Fischer, W., Gillor, D., Macias, L.M., DuVal, A., Rothman, R., Dugas, A., Ruiz-Palacios, G.M., Reliability, validity, and responsiveness of InFLUenza patient-reported outcome (FLU-PRO(c)) scores in influenza-positive patients. Value Health 21 (2018), 210–218.
-
(2018)
Value Health
, vol.21
, pp. 210-218
-
-
Powers, J.H.1
Bacci, E.D.2
Guerrero, M.L.3
Leidy, N.K.4
Stringer, S.5
Kim, K.6
Memoli, M.J.7
Han, A.8
Fairchok, M.P.9
Chen, W.J.10
Arnold, J.C.11
Danaher, P.J.12
Lalani, T.13
Ridore, M.14
Burgess, T.H.15
Millar, E.V.16
Hernandez, A.17
Rodriguez-Zulueta, P.18
Smolskis, M.C.19
Ortega-Gallegos, H.20
Pett, S.21
Fischer, W.22
Gillor, D.23
Macias, L.M.24
DuVal, A.25
Rothman, R.26
Dugas, A.27
Ruiz-Palacios, G.M.28
more..
-
112
-
-
41149091133
-
Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge
-
Rockx, B., Corti, D., Donaldson, E., Sheahan, T., Stadler, K., Lanzavecchia, A., Baric, R., Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge. J. Virol. 82 (2008), 3220–3235.
-
(2008)
J. Virol.
, vol.82
, pp. 3220-3235
-
-
Rockx, B.1
Corti, D.2
Donaldson, E.3
Sheahan, T.4
Stadler, K.5
Lanzavecchia, A.6
Baric, R.7
-
113
-
-
34447273596
-
Synthetic reconstruction of zoonotic and early human severe acute respiratory syndrome coronavirus isolates that produce fatal disease in aged mice
-
Rockx, B., Sheahan, T., Donaldson, E., Harkema, J., Sims, A., Heise, M., Pickles, R., Cameron, M., Kelvin, D., Baric, R., Synthetic reconstruction of zoonotic and early human severe acute respiratory syndrome coronavirus isolates that produce fatal disease in aged mice. J. Virol. 81 (2007), 7410–7423.
-
(2007)
J. Virol.
, vol.81
, pp. 7410-7423
-
-
Rockx, B.1
Sheahan, T.2
Donaldson, E.3
Harkema, J.4
Sims, A.5
Heise, M.6
Pickles, R.7
Cameron, M.8
Kelvin, D.9
Baric, R.10
-
114
-
-
85062366949
-
Corticosteroids as adjunctive therapy in the treatment of influenza
-
Rodrigo, C., Leonardi-Bee, J., Nguyen-Van-Tam, J., Lim, W.S., Corticosteroids as adjunctive therapy in the treatment of influenza. Cochrane Database Syst. Rev., 3, 2016, CD010406.
-
(2016)
Cochrane Database Syst. Rev.
, vol.3
-
-
Rodrigo, C.1
Leonardi-Bee, J.2
Nguyen-Van-Tam, J.3
Lim, W.S.4
-
115
-
-
85063245573
-
Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection
-
Rojas-Quintero, J., Wang, X., Tipper, J., Burkett, P.R., Zuniga, J., Ashtekar, A.R., Polverino, F., Rout, A., Yambayev, I., Hernandez, C., Jimenez, L., Ramirez, G., Harrod, K.S., Owen, C.A., Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection. JCI Insight, 3, 2018.
-
(2018)
JCI Insight
, vol.3
-
-
Rojas-Quintero, J.1
Wang, X.2
Tipper, J.3
Burkett, P.R.4
Zuniga, J.5
Ashtekar, A.R.6
Polverino, F.7
Rout, A.8
Yambayev, I.9
Hernandez, C.10
Jimenez, L.11
Ramirez, G.12
Harrod, K.S.13
Owen, C.A.14
-
116
-
-
84906669535
-
Nitazoxanide: a first-in-class broad-spectrum antiviral agent
-
Rossignol, J.F., Nitazoxanide: a first-in-class broad-spectrum antiviral agent. Antivir. Res. 110 (2014), 94–103.
-
(2014)
Antivir. Res.
, vol.110
, pp. 94-103
-
-
Rossignol, J.F.1
-
118
-
-
85064131362
-
1062: compassionate use of intravenous (IV) zanamivir during the 2013-2014 influenza season: case series of three patients
-
S311-S311
-
Shah, P., Grein, J., Vakil, N., Hirai-Yang, A., Murthy, R., 1062: compassionate use of intravenous (IV) zanamivir during the 2013-2014 influenza season: case series of three patients. Open Forum Infect. Dis., 1, 2014 S311-S311.
-
(2014)
Open Forum Infect. Dis.
, vol.1
-
-
Shah, P.1
Grein, J.2
Vakil, N.3
Hirai-Yang, A.4
Murthy, R.5
-
119
-
-
85049589477
-
Update on nitazoxanide: a multifunctional chemotherapeutic agent
-
Shakya, A., Bhat, H.R., Ghosh, S.K., Update on nitazoxanide: a multifunctional chemotherapeutic agent. Curr. Drug Discov. Technol. 15 (2018), 201–213.
-
(2018)
Curr. Drug Discov. Technol.
, vol.15
, pp. 201-213
-
-
Shakya, A.1
Bhat, H.R.2
Ghosh, S.K.3
-
120
-
-
85056513992
-
Critically ill healthcare workers with the middle east respiratory syndrome (MERS): a multicenter study
-
Shalhoub, S., Al-Hameed, F., Mandourah, Y., Balkhy, H.H., Al-Omari, A., Al Mekhlafi, G.A., Kharaba, A., Alraddadi, B., Almotairi, A., Al Khatib, K., Abdulmomen, A., Qushmaq, I., Mady, A., Solaiman, O., Al-Aithan, A.M., Al-Raddadi, R., Ragab, A., Al Harthy, A., Al Qasim, E., Jose, J., Al-Ghamdi, G., Merson, L., Fowler, R., Hayden, F.G., Arabi, Y.M., Critically ill healthcare workers with the middle east respiratory syndrome (MERS): a multicenter study. PLoS One, 13, 2018, e0206831.
-
(2018)
PLoS One
, vol.13
-
-
Shalhoub, S.1
Al-Hameed, F.2
Mandourah, Y.3
Balkhy, H.H.4
Al-Omari, A.5
Al Mekhlafi, G.A.6
Kharaba, A.7
Alraddadi, B.8
Almotairi, A.9
Al Khatib, K.10
Abdulmomen, A.11
Qushmaq, I.12
Mady, A.13
Solaiman, O.14
Al-Aithan, A.M.15
Al-Raddadi, R.16
Ragab, A.17
Al Harthy, A.18
Al Qasim, E.19
Jose, J.20
Al-Ghamdi, G.21
Merson, L.22
Fowler, R.23
Hayden, F.G.24
Arabi, Y.M.25
more..
-
121
-
-
50149120731
-
Pathways of cross-species transmission of synthetically reconstructed zoonotic severe acute respiratory syndrome coronavirus
-
Sheahan, T., Rockx, B., Donaldson, E., Corti, D., Baric, R., Pathways of cross-species transmission of synthetically reconstructed zoonotic severe acute respiratory syndrome coronavirus. J. Virol. 82 (2008), 8721–8732.
-
(2008)
J. Virol.
, vol.82
, pp. 8721-8732
-
-
Sheahan, T.1
Rockx, B.2
Donaldson, E.3
Corti, D.4
Baric, R.5
-
122
-
-
39749177748
-
Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium
-
Sheahan, T., Rockx, B., Donaldson, E., Sims, A., Pickles, R., Corti, D., Baric, R., Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium. J. Virol. 82 (2008), 2274–2285.
-
(2008)
J. Virol.
, vol.82
, pp. 2274-2285
-
-
Sheahan, T.1
Rockx, B.2
Donaldson, E.3
Sims, A.4
Pickles, R.5
Corti, D.6
Baric, R.7
-
123
-
-
85021671152
-
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
-
Sheahan, T.P., Sims, A.C., Graham, R.L., Menachery, V.D., Gralinski, L.E., Case, J.B., Leist, S.R., Pyrc, K., Feng, J.Y., Trantcheva, I., Bannister, R., Park, Y., Babusis, D., Clarke, M.O., Mackman, R.L., Spahn, J.E., Palmiotti, C.A., Siegel, D., Ray, A.S., Cihlar, T., Jordan, R., Denison, M.R., Baric, R.S., Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses. Sci. Transl. Med., 9, 2017.
-
(2017)
Sci. Transl. Med.
, vol.9
-
-
Sheahan, T.P.1
Sims, A.C.2
Graham, R.L.3
Menachery, V.D.4
Gralinski, L.E.5
Case, J.B.6
Leist, S.R.7
Pyrc, K.8
Feng, J.Y.9
Trantcheva, I.10
Bannister, R.11
Park, Y.12
Babusis, D.13
Clarke, M.O.14
Mackman, R.L.15
Spahn, J.E.16
Palmiotti, C.A.17
Siegel, D.18
Ray, A.S.19
Cihlar, T.20
Jordan, R.21
Denison, M.R.22
Baric, R.S.23
more..
-
124
-
-
85021970644
-
Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study
-
Shi, T., McAllister, D.A., O'Brien, K.L., Simoes, E.A.F., Madhi, S.A., Gessner, B.D., Polack, F.P., Balsells, E., Acacio, S., Aguayo, C., Alassani, I., Ali, A., Antonio, M., Awasthi, S., Awori, J.O., Azziz-Baumgartner, E., Baggett, H.C., Baillie, V.L., Balmaseda, A., Barahona, A., Basnet, S., Bassat, Q., Basualdo, W., Bigogo, G., Bont, L., Breiman, R.F., Brooks, W.A., Broor, S., Bruce, N., Bruden, D., Buchy, P., Campbell, S., Carosone-Link, P., Chadha, M., Chipeta, J., Chou, M., Clara, W., Cohen, C., de Cuellar, E., Dang, D.A., Dash-Yandag, B., Deloria-Knoll, M., Dherani, M., Eap, T., Ebruke, B.E., Echavarria, M., de Freitas Lazaro Emediato, C.C., Fasce, R.A., Feikin, D.R., Feng, L., Gentile, A., Gordon, A., Goswami, D., Goyet, S., Groome, M., Halasa, N., Hirve, S., Homaira, N., Howie, S.R.C., Jara, J., Jroundi, I., Kartasasmita, C.B., Khuri-Bulos, N., Kotloff, K.L., Krishnan, A., Libster, R., Lopez, O., Lucero, M.G., Lucion, F., Lupisan, S.P., Marcone, D.N., McCracken, J.P., Mejia, M., Moisi, J.C., Montgomery, J.M., Moore, D.P., Moraleda, C., Moyes, J., Munywoki, P., Mutyara, K., Nicol, M.P., Nokes, D.J., Nymadawa, P., da Costa Oliveira, M.T., Oshitani, H., Pandey, N., Paranhos-Baccala, G., Phillips, L.N., Picot, V.S., Rahman, M., Rakoto-Andrianarivelo, M., Rasmussen, Z.A., Rath, B.A., Robinson, A., Romero, C., Russomando, G., Salimi, V., Sawatwong, P., Scheltema, N., Schweiger, B., Scott, J.A.G., Seidenberg, P., Shen, K., Singleton, R., Sotomayor, V., Strand, T.A., Sutanto, A., Sylla, M., Tapia, M.D., Thamthitiwat, S., Thomas, E.D., Tokarz, R., Turner, C., Venter, M., Waicharoen, S., Wang, J., Watthanaworawit, W., Yoshida, L.M., Yu, H., Zar, H.J., Campbell, H., Nair, H., Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study. Lancet 390 (2017), 946–958.
-
(2017)
Lancet
, vol.390
, pp. 946-958
-
-
Shi, T.1
McAllister, D.A.2
O'Brien, K.L.3
Simoes, E.A.F.4
Madhi, S.A.5
Gessner, B.D.6
Polack, F.P.7
Balsells, E.8
Acacio, S.9
Aguayo, C.10
Alassani, I.11
Ali, A.12
Antonio, M.13
Awasthi, S.14
Awori, J.O.15
Azziz-Baumgartner, E.16
Baggett, H.C.17
Baillie, V.L.18
Balmaseda, A.19
Barahona, A.20
Basnet, S.21
Bassat, Q.22
Basualdo, W.23
Bigogo, G.24
Bont, L.25
Breiman, R.F.26
Brooks, W.A.27
Broor, S.28
Bruce, N.29
Bruden, D.30
Buchy, P.31
Campbell, S.32
Carosone-Link, P.33
Chadha, M.34
Chipeta, J.35
Chou, M.36
Clara, W.37
Cohen, C.38
de Cuellar, E.39
Dang, D.A.40
Dash-Yandag, B.41
Deloria-Knoll, M.42
Dherani, M.43
Eap, T.44
Ebruke, B.E.45
Echavarria, M.46
de Freitas Lazaro Emediato, C.C.47
Fasce, R.A.48
Feikin, D.R.49
Feng, L.50
Gentile, A.51
Gordon, A.52
Goswami, D.53
Goyet, S.54
Groome, M.55
Halasa, N.56
Hirve, S.57
Homaira, N.58
Howie, S.R.C.59
Jara, J.60
Jroundi, I.61
Kartasasmita, C.B.62
Khuri-Bulos, N.63
Kotloff, K.L.64
Krishnan, A.65
Libster, R.66
Lopez, O.67
Lucero, M.G.68
Lucion, F.69
Lupisan, S.P.70
Marcone, D.N.71
McCracken, J.P.72
Mejia, M.73
Moisi, J.C.74
Montgomery, J.M.75
Moore, D.P.76
Moraleda, C.77
Moyes, J.78
Munywoki, P.79
Mutyara, K.80
Nicol, M.P.81
Nokes, D.J.82
Nymadawa, P.83
da Costa Oliveira, M.T.84
Oshitani, H.85
Pandey, N.86
Paranhos-Baccala, G.87
Phillips, L.N.88
Picot, V.S.89
Rahman, M.90
Rakoto-Andrianarivelo, M.91
Rasmussen, Z.A.92
Rath, B.A.93
Robinson, A.94
Romero, C.95
Russomando, G.96
Salimi, V.97
Sawatwong, P.98
Scheltema, N.99
Schweiger, B.100
Scott, J.A.G.101
Seidenberg, P.102
Shen, K.103
Singleton, R.104
Sotomayor, V.105
Strand, T.A.106
Sutanto, A.107
Sylla, M.108
Tapia, M.D.109
Thamthitiwat, S.110
Thomas, E.D.111
Tokarz, R.112
Turner, C.113
Venter, M.114
Waicharoen, S.115
Wang, J.116
Watthanaworawit, W.117
Yoshida, L.M.118
Yu, H.119
Zar, H.J.120
Campbell, H.121
Nair, H.122
more..
-
125
-
-
84878141871
-
The TLR4 antagonist Eritoran protects mice from lethal influenza infection
-
Shirey, K.A., Lai, W., Scott, A.J., Lipsky, M., Mistry, P., Pletneva, L.M., Karp, C.L., McAlees, J., Gioannini, T.L., Weiss, J., Chen, W.H., Ernst, R.K., Rossignol, D.P., Gusovsky, F., Blanco, J.C., Vogel, S.N., The TLR4 antagonist Eritoran protects mice from lethal influenza infection. Nature 497 (2013), 498–502.
-
(2013)
Nature
, vol.497
, pp. 498-502
-
-
Shirey, K.A.1
Lai, W.2
Scott, A.J.3
Lipsky, M.4
Mistry, P.5
Pletneva, L.M.6
Karp, C.L.7
McAlees, J.8
Gioannini, T.L.9
Weiss, J.10
Chen, W.H.11
Ernst, R.K.12
Rossignol, D.P.13
Gusovsky, F.14
Blanco, J.C.15
Vogel, S.N.16
-
126
-
-
85015071018
-
Discovery and synthesis of a phosphoramidate prodrug of a pyrrolo[2,1-f][triazin-4-amino] adenine C-nucleoside (GS-5734) for the treatment of Ebola and emerging viruses
-
Siegel, D., Hui, H.C., Doerffler, E., Clarke, M.O., Chun, K., Zhang, L., Neville, S., Carra, E., Lew, W., Ross, B., Wang, Q., Wolfe, L., Jordan, R., Soloveva, V., Knox, J., Perry, J., Perron, M., Stray, K.M., Barauskas, O., Feng, J.Y., Xu, Y., Lee, G., Rheingold, A.L., Ray, A.S., Bannister, R., Strickley, R., Swaminathan, S., Lee, W.A., Bavari, S., Cihlar, T., Lo, M.K., Warren, T.K., Mackman, R.L., Discovery and synthesis of a phosphoramidate prodrug of a pyrrolo[2,1-f][triazin-4-amino] adenine C-nucleoside (GS-5734) for the treatment of Ebola and emerging viruses. J. Med. Chem. 60 (2017), 1648–1661.
-
(2017)
J. Med. Chem.
, vol.60
, pp. 1648-1661
-
-
Siegel, D.1
Hui, H.C.2
Doerffler, E.3
Clarke, M.O.4
Chun, K.5
Zhang, L.6
Neville, S.7
Carra, E.8
Lew, W.9
Ross, B.10
Wang, Q.11
Wolfe, L.12
Jordan, R.13
Soloveva, V.14
Knox, J.15
Perry, J.16
Perron, M.17
Stray, K.M.18
Barauskas, O.19
Feng, J.Y.20
Xu, Y.21
Lee, G.22
Rheingold, A.L.23
Ray, A.S.24
Bannister, R.25
Strickley, R.26
Swaminathan, S.27
Lee, W.A.28
Bavari, S.29
Cihlar, T.30
Lo, M.K.31
Warren, T.K.32
Mackman, R.L.33
more..
-
127
-
-
84992128569
-
Synthesis and pre-clinical studies of new amino-acid ester thiazolide prodrugs
-
Stachulski, A.V., Swift, K., Cooper, M., Reynolds, S., Norton, D., Slonecker, S.D., Rossignol, J.F., Synthesis and pre-clinical studies of new amino-acid ester thiazolide prodrugs. Eur. J. Med. Chem. 126 (2017), 154–159.
-
(2017)
Eur. J. Med. Chem.
, vol.126
, pp. 154-159
-
-
Stachulski, A.V.1
Swift, K.2
Cooper, M.3
Reynolds, S.4
Norton, D.5
Slonecker, S.D.6
Rossignol, J.F.7
-
128
-
-
84884683675
-
Mutational analysis of the binding pockets of the diketo acid inhibitor L-742,001 in the influenza virus PA endonuclease
-
Stevaert, A., Dallocchio, R., Dessi, A., Pala, N., Rogolino, D., Sechi, M., Naesens, L., Mutational analysis of the binding pockets of the diketo acid inhibitor L-742,001 in the influenza virus PA endonuclease. J. Virol. 87 (2013), 10524–10538.
-
(2013)
J. Virol.
, vol.87
, pp. 10524-10538
-
-
Stevaert, A.1
Dallocchio, R.2
Dessi, A.3
Pala, N.4
Rogolino, D.5
Sechi, M.6
Naesens, L.7
-
129
-
-
85055673905
-
Antiviral activity of oral JNJ-53718678 in healthy adult volunteers challenged with respiratory syncytial virus: a placebo-controlled study
-
Stevens, M., Rusch, S., DeVincenzo, J., Kim, Y.I., Harrison, L., Meals, E.A., Boyers, A., Fok-Seang, J., Huntjens, D., Lounis, N., Mari, N.K., Remmerie, B., Roymans, D., Koul, A., Verloes, R., Antiviral activity of oral JNJ-53718678 in healthy adult volunteers challenged with respiratory syncytial virus: a placebo-controlled study. J. Infect. Dis. 218 (2018), 748–756.
-
(2018)
J. Infect. Dis.
, vol.218
, pp. 748-756
-
-
Stevens, M.1
Rusch, S.2
DeVincenzo, J.3
Kim, Y.I.4
Harrison, L.5
Meals, E.A.6
Boyers, A.7
Fok-Seang, J.8
Huntjens, D.9
Lounis, N.10
Mari, N.K.11
Remmerie, B.12
Roymans, D.13
Koul, A.14
Verloes, R.15
-
130
-
-
85058157623
-
Susceptibility of influenza viruses to the novel cap-dependent endonuclease inhibitor baloxavir marboxil
-
Takashita, E., Morita, H., Ogawa, R., Nakamura, K., Fujisaki, S., Shirakura, M., Kuwahara, T., Kishida, N., Watanabe, S., Odagiri, T., Susceptibility of influenza viruses to the novel cap-dependent endonuclease inhibitor baloxavir marboxil. Front. Microbiol., 9, 2018, 3026.
-
(2018)
Front. Microbiol.
, vol.9
, pp. 3026
-
-
Takashita, E.1
Morita, H.2
Ogawa, R.3
Nakamura, K.4
Fujisaki, S.5
Shirakura, M.6
Kuwahara, T.7
Kishida, N.8
Watanabe, S.9
Odagiri, T.10
-
131
-
-
0003077113
-
A Regulatory Authority's Opinion about Surrogate Endpoints
-
J. Wiley New York
-
Temple, R.J., A Regulatory Authority's Opinion about Surrogate Endpoints. 1995, J. Wiley, New York.
-
(1995)
-
-
Temple, R.J.1
-
132
-
-
84940981698
-
A broadly neutralizing human monoclonal antibody is effective against H7N9
-
Tharakaraman, K., Subramanian, V., Viswanathan, K., Sloan, S., Yen, H.L., Barnard, D.L., Leung, Y.H., Szretter, K.J., Koch, T.J., Delaney, J.C., Babcock, G.J., Wogan, G.N., Sasisekharan, R., Shriver, Z., A broadly neutralizing human monoclonal antibody is effective against H7N9. Proc. Natl. Acad. Sci. U. S. A. 112 (2015), 10890–10895.
-
(2015)
Proc. Natl. Acad. Sci. U. S. A.
, vol.112
, pp. 10890-10895
-
-
Tharakaraman, K.1
Subramanian, V.2
Viswanathan, K.3
Sloan, S.4
Yen, H.L.5
Barnard, D.L.6
Leung, Y.H.7
Szretter, K.J.8
Koch, T.J.9
Delaney, J.C.10
Babcock, G.J.11
Wogan, G.N.12
Sasisekharan, R.13
Shriver, Z.14
-
133
-
-
85053161710
-
Pimodivir treatment in adult volunteers experimentally inoculated with live influenza virus: a Phase IIa, randomized, double-blind, placebo-controlled study
-
Trevejo, J.M., Asmal, M., Vingerhoets, J., Polo, R., Robertson, S., Jiang, Y., Kieffer, T.L., Leopold, L., Pimodivir treatment in adult volunteers experimentally inoculated with live influenza virus: a Phase IIa, randomized, double-blind, placebo-controlled study. Antivir. Ther. 23 (2018), 335–344.
-
(2018)
Antivir. Ther.
, vol.23
, pp. 335-344
-
-
Trevejo, J.M.1
Asmal, M.2
Vingerhoets, J.3
Polo, R.4
Robertson, S.5
Jiang, Y.6
Kieffer, T.L.7
Leopold, L.8
-
134
-
-
33746261692
-
Guidance for Industry - Patient-Reported Outcome Measures: Use in Medical Product Development to Support Labeling Claims
-
U.S. Food & Drug Administration, Guidance for Industry - Patient-Reported Outcome Measures: Use in Medical Product Development to Support Labeling Claims. 2009.
-
(2009)
-
-
-
135
-
-
84872501381
-
Guidance for Industry - Influenza: Developing Drugs for Treatment And/or Prophylaxis
-
U.S. Food & Drug Administration, Guidance for Industry - Influenza: Developing Drugs for Treatment And/or Prophylaxis. 2011.
-
(2011)
-
-
-
136
-
-
84921730324
-
Guidance for Industry - Immunogenicity Assessment for Therapeutic Protein Products
-
U.S. Food & Drug Administration, Guidance for Industry - Immunogenicity Assessment for Therapeutic Protein Products. 2014.
-
(2014)
-
-
-
137
-
-
85064140617
-
Respiratory Syncytial Virus Infection: Developing Antiviral Drugs for Prophylaxis and Treatment
-
Guidance for Industry
-
U.S. Food & Drug Administration, Respiratory Syncytial Virus Infection: Developing Antiviral Drugs for Prophylaxis and Treatment. 2017, Guidance for Industry.
-
(2017)
-
-
-
138
-
-
85064121714
-
Critical Path Innovation Meetings (CPIM)
-
U.S. Food & Drug Administration. Critical Path Innovation Meetings (CPIM). 2018.
-
(2018)
-
-
-
139
-
-
84893289257
-
Adjuvant treatment with a mammalian target of rapamycin inhibitor, sirolimus, and steroids improves outcomes in patients with severe H1N1 pneumonia and acute respiratory failure
-
Wang, C.H., Chung, F.T., Lin, S.M., Huang, S.Y., Chou, C.L., Lee, K.Y., Lin, T.Y., Kuo, H.P., Adjuvant treatment with a mammalian target of rapamycin inhibitor, sirolimus, and steroids improves outcomes in patients with severe H1N1 pneumonia and acute respiratory failure. Crit. Care Med. 42 (2014), 313–321.
-
(2014)
Crit. Care Med.
, vol.42
, pp. 313-321
-
-
Wang, C.H.1
Chung, F.T.2
Lin, S.M.3
Huang, S.Y.4
Chou, C.L.5
Lee, K.Y.6
Lin, T.Y.7
Kuo, H.P.8
-
140
-
-
84982234143
-
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys
-
Warren, T.K., Jordan, R., Lo, M.K., Ray, A.S., Mackman, R.L., Soloveva, V., Siegel, D., Perron, M., Bannister, R., Hui, H.C., Larson, N., Strickley, R., Wells, J., Stuthman, K.S., Van Tongeren, S.A., Garza, N.L., Donnelly, G., Shurtleff, A.C., Retterer, C.J., Gharaibeh, D., Zamani, R., Kenny, T., Eaton, B.P., Grimes, E., Welch, L.S., Gomba, L., Wilhelmsen, C.L., Nichols, D.K., Nuss, J.E., Nagle, E.R., Kugelman, J.R., Palacios, G., Doerffler, E., Neville, S., Carra, E., Clarke, M.O., Zhang, L., Lew, W., Ross, B., Wang, Q., Chun, K., Wolfe, L., Babusis, D., Park, Y., Stray, K.M., Trancheva, I., Feng, J.Y., Barauskas, O., Xu, Y., Wong, P., Braun, M.R., Flint, M., McMullan, L.K., Chen, S.S., Fearns, R., Swaminathan, S., Mayers, D.L., Spiropoulou, C.F., Lee, W.A., Nichol, S.T., Cihlar, T., Bavari, S., Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys. Nature 531 (2016), 381–385.
-
(2016)
Nature
, vol.531
, pp. 381-385
-
-
Warren, T.K.1
Jordan, R.2
Lo, M.K.3
Ray, A.S.4
Mackman, R.L.5
Soloveva, V.6
Siegel, D.7
Perron, M.8
Bannister, R.9
Hui, H.C.10
Larson, N.11
Strickley, R.12
Wells, J.13
Stuthman, K.S.14
Van Tongeren, S.A.15
Garza, N.L.16
Donnelly, G.17
Shurtleff, A.C.18
Retterer, C.J.19
Gharaibeh, D.20
Zamani, R.21
Kenny, T.22
Eaton, B.P.23
Grimes, E.24
Welch, L.S.25
Gomba, L.26
Wilhelmsen, C.L.27
Nichols, D.K.28
Nuss, J.E.29
Nagle, E.R.30
Kugelman, J.R.31
Palacios, G.32
Doerffler, E.33
Neville, S.34
Carra, E.35
Clarke, M.O.36
Zhang, L.37
Lew, W.38
Ross, B.39
Wang, Q.40
Chun, K.41
Wolfe, L.42
Babusis, D.43
Park, Y.44
Stray, K.M.45
Trancheva, I.46
Feng, J.Y.47
Barauskas, O.48
Xu, Y.49
Wong, P.50
Braun, M.R.51
Flint, M.52
McMullan, L.K.53
Chen, S.S.54
Fearns, R.55
Swaminathan, S.56
Mayers, D.L.57
Spiropoulou, C.F.58
Lee, W.A.59
Nichol, S.T.60
Cihlar, T.61
Bavari, S.62
more..
-
141
-
-
12244295453
-
Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the neuraminidase inhibitor susceptibility network
-
Wetherall, N.T., Trivedi, T., Zeller, J., Hodges-Savola, C., McKimm-Breschkin, J.L., Zambon, M., Hayden, F.G., Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the neuraminidase inhibitor susceptibility network. J. Clin. Microbiol. 41 (2003), 742–750.
-
(2003)
J. Clin. Microbiol.
, vol.41
, pp. 742-750
-
-
Wetherall, N.T.1
Trivedi, T.2
Zeller, J.3
Hodges-Savola, C.4
McKimm-Breschkin, J.L.5
Zambon, M.6
Hayden, F.G.7
-
142
-
-
85051995485
-
Highlights of Prescribing Information
-
Xofluza, Highlights of Prescribing Information. 2018.
-
(2018)
-
-
Xofluza1
-
143
-
-
84856112765
-
Antiviral therapy and outcomes of patients with pneumonia caused by influenza A pandemic (H1N1) virus
-
Yang, S.G., Cao, B., Liang, L.R., Li, X.L., Xiao, Y.H., Cao, Z.X., Jia, H.Y., Yu, H.J., Xu, Z., Gu, L., Yang, Y.D., Chen, Y., Du, W.B., Yan, X.X., Liang, Z.A., Zhang, W., Zhang, C.L., Chen, W., Guo, C.P., Jiang, X.L., Yang, M., Deng, G.M., Yu, K.J., Hu, K., Zou, Q., Li, L.J., Wang, C., National Influenza, A.P.C.I.G.o.C. Antiviral therapy and outcomes of patients with pneumonia caused by influenza A pandemic (H1N1) virus. PLoS One, 7, 2012, e29652.
-
(2012)
PLoS One
, vol.7
-
-
Yang, S.G.1
Cao, B.2
Liang, L.R.3
Li, X.L.4
Xiao, Y.H.5
Cao, Z.X.6
Jia, H.Y.7
Yu, H.J.8
Xu, Z.9
Gu, L.10
Yang, Y.D.11
Chen, Y.12
Du, W.B.13
Yan, X.X.14
Liang, Z.A.15
Zhang, W.16
Zhang, C.L.17
Chen, W.18
Guo, C.P.19
Jiang, X.L.20
Yang, M.21
Deng, G.M.22
Yu, K.J.23
Hu, K.24
Zou, Q.25
Li, L.J.26
Wang, C.27
more..
-
144
-
-
85052024066
-
Orally efficacious broad-spectrum ribonucleoside analog inhibitor of influenza and respiratory syncytial viruses
-
Yoon, J.J., Toots, M., Lee, S., Lee, M.E., Ludeke, B., Luczo, J.M., Ganti, K., Cox, R.M., Sticher, Z.M., Edpuganti, V., Mitchell, D.G., Lockwood, M.A., Kolykhalov, A.A., Greninger, A.L., Moore, M.L., Painter, G.R., Lowen, A.C., Tompkins, S.M., Fearns, R., Natchus, M.G., Plemper, R.K., Orally efficacious broad-spectrum ribonucleoside analog inhibitor of influenza and respiratory syncytial viruses. Antimicrob. Agents Chemother., 62, 2018.
-
(2018)
Antimicrob. Agents Chemother.
, vol.62
-
-
Yoon, J.J.1
Toots, M.2
Lee, S.3
Lee, M.E.4
Ludeke, B.5
Luczo, J.M.6
Ganti, K.7
Cox, R.M.8
Sticher, Z.M.9
Edpuganti, V.10
Mitchell, D.G.11
Lockwood, M.A.12
Kolykhalov, A.A.13
Greninger, A.L.14
Moore, M.L.15
Painter, G.R.16
Lowen, A.C.17
Tompkins, S.M.18
Fearns, R.19
Natchus, M.G.20
Plemper, R.K.21
more..
-
145
-
-
85006821348
-
Investigational hemagglutinin-targeted influenza virus inhibitors
-
Zeng, L.Y., Yang, J., Liu, S., Investigational hemagglutinin-targeted influenza virus inhibitors. Expert Opin. Investig. Drugs 26 (2017), 63–73.
-
(2017)
Expert Opin. Investig. Drugs
, vol.26
, pp. 63-73
-
-
Zeng, L.Y.1
Yang, J.2
Liu, S.3
|