Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

Science

Volumn 362, Issue 6414, 2018, Pages 598-602

  Laursen, Nick S ^a,h   Friesen, Robert H E ^b,i   Zhu, Xueyong ^a   Jongeneelen, Mandy ^c   Blokland, Sven ^c   Vermond, Jan ^d   Van Eijgen, Alida ^d   Tang, Chan ^c   Van Diepen, Harry ^d   Obmolova, Galina ^b   Van Der Neut Kolfschoten, Marijn ^c   Zuijdgeest, David ^c   Straetemans, Roel ^e   Hoffman, Ryan M B ^a   Nieusma, Travis ^a   Pallesen, Jesper ^a   Turner, Hannah L ^a   Bernard, Steffen M ^a   Ward, Andrew B ^a   Luo, Jinquan ^b   Poon, Leo L M ^f   Tretiakova, Anna P ^g,j   Wilson, James M ^g   Limberis, Maria P ^g   Vogels, Ronald ^c   Brandenburg, Boerries ^c   Kolkman, Joost A ^e   Wilson, Ian A ^a   more..

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^c Janssen Research and Development   (Netherlands)

^d Janssen Prevention Center   (Netherlands)

^e JANSSEN RESEARCH FOUNDATION   (Belgium)

^f UNIVERSITY OF HONG KONG   (Hong Kong)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

^h AARHUS UNIVERSITY   (Denmark)

ⁱ ABLYNX NV   (Belgium)

^j PFIZER INC   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADENO ASSOCIATED VIRUS VECTOR; EPITOPE; INFLUENZA VIRUS HEMAGGLUTININ ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; NANOBODY; NEUTRALIZING ANTIBODY; RECOMBINANT PROTEIN; VIRUS ANTIBODY;

ANTIBODY RESPONSE; ANTIBODY STRUCTURE; ARTICLE; CRYSTAL STRUCTURE; ELECTRON MICROSCOPY; GENE TARGETING; HUMAN; INFECTION PREVENTION; INFLUENZA; INFLUENZA A VIRUS; INFLUENZA B VIRUS; PRIORITY JOURNAL; PROTEIN DOMAIN; VIRUS ATTACHMENT; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; DOG; FEMALE; GENETICS; IMMUNOLOGY; MDCK CELL LINE; MOUSE; NEW WORLD CAMELID; ORTHOMYXOVIRUS INFECTION; PEPTIDE LIBRARY; SERODIAGNOSIS; ULTRASTRUCTURE; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CAMELIDS, NEW WORLD; CRYSTALLOGRAPHY, X-RAY; DOGS; FEMALE; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; IMMUNODOMINANT EPITOPES; INFLUENZA A VIRUS; INFLUENZA B VIRUS; INFLUENZA VACCINES; MADIN DARBY CANINE KIDNEY CELLS; MICE; MICE, INBRED BALB C; NEUTRALIZATION TESTS; ORTHOMYXOVIRIDAE INFECTIONS; PEPTIDE LIBRARY; RECOMBINANT PROTEINS; SINGLE-DOMAIN ANTIBODIES;

EID: 85055907907     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaq0620     Document Type: Article

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