Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection

JCI insight

Volumn 3, Issue 24, 2018, Pages

  Rojas Quintero, Joselyn ^a   Wang, Xiaoyun ^a   Tipper, Jennifer ^b   Burkett, Patrick R ^a   Zuñiga, Joaquin ^c   Ashtekar, Amit R ^b   Polverino, Francesca ^a,d   Rout, Amit ^a   Yambayev, Ilyas ^a   Hernández, Carmen ^c,e   Jimenez, Luis ^c   Ramírez, Gustavo ^c   Harrod, Kevin S ^b   Owen, Caroline A ^a,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

^d LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^e ESCUELA DE MEDICINA Y CIENCIAS DE LA SALUD   (Mexico)

Author keywords

Infectious disease; Influenza; Mouse models; Pulmonology

Indexed keywords

GAMMA INTERFERON; GELATINASE B; INTERFERON;

ANIMAL; BLOOD; BODY WEIGHT LOSS; C57BL MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; DISEASE MODEL; EPITHELIUM CELL; FEMALE; GENE EXPRESSION PROFILING; GENETICS; HUMAN; IMMUNOLOGY; INFLUENZA; INFLUENZA A VIRUS (H1N1); KNOCKOUT MOUSE; LEUKOCYTE; LUNG; LUNG INJURY; MALE; METABOLISM; MOUSE; ORTHOMYXOVIRUS INFECTION; VIROLOGY;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; INTERFERON TYPE I; INTERFERON-GAMMA; LEUKOCYTES; LUNG; LUNG INJURY; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORTHOMYXOVIRIDAE INFECTIONS; WEIGHT LOSS;

EID: 85063245573     PISSN: None     EISSN: 23793708     Source Type: Journal    
DOI: 10.1172/jci.insight.99022     Document Type: Article

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