메뉴 건너뛰기




Volumn 26, Issue 9, 2019, Pages 1796-1812

Sphingolipid-mediated inflammatory signaling leading to autophagy inhibition converts erythropoiesis to myelopoiesis in human hematopoietic stem/progenitor cells

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY RELATED PROTEIN; AUTOPHAGY RELATED PROTEIN 13; AUTOPHAGY RELATED PROTEIN 5; CD34 ANTIGEN; CERAMIDE; MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA; MICRORNA 144; MICRORNA 146A; MICRORNA 155; MICRORNA 223; MICRORNA 451; SERINE THREONINE PROTEIN KINASE ULK1; SMALL INTERFERING RNA; SPHINGOLIPID; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELIN PHOSPHODIESTERASE 3; SPHINGOSINE 1 PHOSPHATE; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR PU 1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

EID: 85058620111     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/s41418-018-0245-x     Document Type: Article
Times cited : (61)

References (60)
  • 1
    • 21744439534 scopus 로고    scopus 로고
    • The anaemia of cancer: death by a thousand cuts
    • COI: 1:CAS:528:DC%2BD2MXmtFOnsL0%3D
    • Spivak JL. The anaemia of cancer: death by a thousand cuts. Nat Rev Cancer. 2005;5:543–55.
    • (2005) Nat Rev Cancer , vol.5 , pp. 543-555
    • Spivak, J.L.1
  • 2
    • 79958159238 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha-mediated inhibition of erythropoiesis involves GATA-1/GATA-2 balance impairment and PU.1 over-expression
    • COI: 1:CAS:528:DC%2BC3MXntVyru7g%3D
    • Grigorakaki C, Morceau F, Chateauvieux S, Dicato M, Diederich M. Tumor necrosis factor alpha-mediated inhibition of erythropoiesis involves GATA-1/GATA-2 balance impairment and PU.1 over-expression. Biochem Pharmacol. 2011;82:156–66.
    • (2011) Biochem Pharmacol , vol.82 , pp. 156-166
    • Grigorakaki, C.1    Morceau, F.2    Chateauvieux, S.3    Dicato, M.4    Diederich, M.5
  • 3
    • 64049095648 scopus 로고    scopus 로고
    • The inhibitory effect of the proinflammatory cytokine TNFalpha on erythroid differentiation involves erythroid transcription factor modulation
    • COI: 1:CAS:528:DC%2BD1MXjs1KgtL4%3D, PID: 19212691
    • Buck I, Morceau F, Cristofanon S, Reuter S, Dicato M, Diederich M. The inhibitory effect of the proinflammatory cytokine TNFalpha on erythroid differentiation involves erythroid transcription factor modulation. Int J Oncol. 2009;34:853–60.
    • (2009) Int J Oncol , vol.34 , pp. 853-860
    • Buck, I.1    Morceau, F.2    Cristofanon, S.3    Reuter, S.4    Dicato, M.5    Diederich, M.6
  • 4
    • 54049113367 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation
    • COI: 1:CAS:528:DC%2BD1cXhtlSgs77P
    • Buck I, Morceau F, Cristofanon S, Heintz C, Chateauvieux S, Reuter S, et al. Tumor necrosis factor alpha inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation. Biochem Pharmacol. 2008;76:1229–39.
    • (2008) Biochem Pharmacol , vol.76 , pp. 1229-1239
    • Buck, I.1    Morceau, F.2    Cristofanon, S.3    Heintz, C.4    Chateauvieux, S.5    Reuter, S.6
  • 5
    • 33746268316 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha inhibits aclacinomycin A-induced erythroid differentiation of K562 cells via GATA-1
    • COI: 1:CAS:528:DC%2BD28XntlGjtbg%3D
    • Morceau F, Schnekenburger M, Blasius R, Buck I, Dicato M, Diederich M. Tumor necrosis factor alpha inhibits aclacinomycin A-induced erythroid differentiation of K562 cells via GATA-1. Cancer Lett. 2006;240:203–12.
    • (2006) Cancer Lett , vol.240 , pp. 203-212
    • Morceau, F.1    Schnekenburger, M.2    Blasius, R.3    Buck, I.4    Dicato, M.5    Diederich, M.6
  • 6
    • 35348892585 scopus 로고    scopus 로고
    • Erythroid and megakaryocytic transformation
    • COI: 1:CAS:528:DC%2BD2sXhtFKhsLnJ
    • Wickrema A, Crispino JD. Erythroid and megakaryocytic transformation. Oncogene. 2007;26:6803–15.
    • (2007) Oncogene , vol.26 , pp. 6803-6815
    • Wickrema, A.1    Crispino, J.D.2
  • 7
    • 84934444744 scopus 로고    scopus 로고
    • Regulation of stem cell populations by microRNAs
    • COI: 1:CAS:528:DC%2BC3sXhvVGhsb3P
    • Mathieu J, Ruohola-Baker H. Regulation of stem cell populations by microRNAs. Adv Exp Med Biol. 2013;786:329–51.
    • (2013) Adv Exp Med Biol , vol.786 , pp. 329-351
    • Mathieu, J.1    Ruohola-Baker, H.2
  • 8
    • 0034541579 scopus 로고    scopus 로고
    • Overexpression of GATA-2 inhibits erythroid and promotes megakaryocyte differentiation
    • COI: 1:CAS:528:DC%2BD3MXotVCr
    • Ikonomi P, Rivera CE, Riordan M, Washington G, Schechter AN, Noguchi CT. Overexpression of GATA-2 inhibits erythroid and promotes megakaryocyte differentiation. Exp Hematol. 2000;28:1423–31.
    • (2000) Exp Hematol , vol.28 , pp. 1423-1431
    • Ikonomi, P.1    Rivera, C.E.2    Riordan, M.3    Washington, G.4    Schechter, A.N.5    Noguchi, C.T.6
  • 10
    • 0034667672 scopus 로고    scopus 로고
    • PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding
    • COI: 1:CAS:528:DC%2BD3cXnt12gsLw%3D
    • Zhang P, Zhang X, Iwama A, Yu C, Smith KA, Mueller BU, et al. PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding. Blood. 2000;96:2641–8.
    • (2000) Blood , vol.96 , pp. 2641-2648
    • Zhang, P.1    Zhang, X.2    Iwama, A.3    Yu, C.4    Smith, K.A.5    Mueller, B.U.6
  • 11
    • 34247483919 scopus 로고    scopus 로고
    • An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling
    • COI: 1:CAS:528:DC%2BD2sXlvVGkuro%3D
    • Fukao T, Fukuda Y, Kiga K, Sharif J, Hino K, Enomoto Y, et al. An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling. Cell. 2007;129:617–31.
    • (2007) Cell , vol.129 , pp. 617-631
    • Fukao, T.1    Fukuda, Y.2    Kiga, K.3    Sharif, J.4    Hino, K.5    Enomoto, Y.6
  • 12
    • 80052149793 scopus 로고    scopus 로고
    • Macrophage development from HSCs requires PU.1-coordinated microRNA expression
    • COI: 1:CAS:528:DC%2BC3MXhtFGisrfP
    • Ghani S, Riemke P, Schonheit J, Lenze D, Stumm J, Hoogenkamp M, et al. Macrophage development from HSCs requires PU.1-coordinated microRNA expression. Blood. 2011;118:2275–84.
    • (2011) Blood , vol.118 , pp. 2275-2284
    • Ghani, S.1    Riemke, P.2    Schonheit, J.3    Lenze, D.4    Stumm, J.5    Hoogenkamp, M.6
  • 13
    • 84880772300 scopus 로고    scopus 로고
    • MicroRNA-mediated control of macrophages and its implications for cancer
    • COI: 1:CAS:528:DC%2BC3sXktVOrsbo%3D
    • Squadrito ML, Etzrodt M, De Palma M, Pittet MJ. MicroRNA-mediated control of macrophages and its implications for cancer. Trends Immunol. 2013;34:350–9.
    • (2013) Trends Immunol , vol.34 , pp. 350-359
    • Squadrito, M.L.1    Etzrodt, M.2    De Palma, M.3    Pittet, M.J.4
  • 14
    • 84880913038 scopus 로고    scopus 로고
    • Autophagy facilitates organelle clearance during differentiation of human erythroblasts: evidence for a role for ATG4 paralogs during autophagosome maturation
    • COI: 1:CAS:528:DC%2BC3sXhvVOnsr%2FN
    • Betin VM, Singleton BK, Parsons SF, Anstee DJ, Lane JD. Autophagy facilitates organelle clearance during differentiation of human erythroblasts: evidence for a role for ATG4 paralogs during autophagosome maturation. Autophagy. 2013;9:881–93.
    • (2013) Autophagy , vol.9 , pp. 881-893
    • Betin, V.M.1    Singleton, B.K.2    Parsons, S.F.3    Anstee, D.J.4    Lane, J.D.5
  • 16
    • 76249127368 scopus 로고    scopus 로고
    • Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo
    • COI: 1:CAS:528:DC%2BC3cXhtFCmsLY%3D
    • Mortensen M, Ferguson DJ, Edelmann M, Kessler B, Morten KJ, Komatsu M, et al. Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo. Proc Natl Acad Sci USA. 2010;107:832–7.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 832-837
    • Mortensen, M.1    Ferguson, D.J.2    Edelmann, M.3    Kessler, B.4    Morten, K.J.5    Komatsu, M.6
  • 17
    • 84922512661 scopus 로고    scopus 로고
    • The generation of neutrophils in the bone marrow is controlled by autophagy
    • COI: 1:CAS:528:DC%2BC2cXhsl2hurzM
    • Rozman S, Yousefi S, Oberson K, Kaufmann T, Benarafa C, Simon HU. The generation of neutrophils in the bone marrow is controlled by autophagy. Cell Death Differ. 2015;22:445–56.
    • (2015) Cell Death Differ , vol.22 , pp. 445-456
    • Rozman, S.1    Yousefi, S.2    Oberson, K.3    Kaufmann, T.4    Benarafa, C.5    Simon, H.U.6
  • 18
    • 84922873168 scopus 로고    scopus 로고
    • Autophagy as a regulatory component of erythropoiesis
    • COI: 1:CAS:528:DC%2BC2MXks1Cjsb8%3D
    • Zhang J, Wu K, Xiao X, Liao J, Hu Q, Chen H, et al. Autophagy as a regulatory component of erythropoiesis. Int J Mol Sci. 2015;16:4083–94.
    • (2015) Int J Mol Sci , vol.16 , pp. 4083-4094
    • Zhang, J.1    Wu, K.2    Xiao, X.3    Liao, J.4    Hu, Q.5    Chen, H.6
  • 19
    • 84962802365 scopus 로고    scopus 로고
    • Regulation of autophagy by signaling through the Atg1/ULK1 complex
    • COI: 1:CAS:528:DC%2BC28Xls1Ojtrs%3D
    • Papinski D, Kraft C. Regulation of autophagy by signaling through the Atg1/ULK1 complex. J Mol Biol. 2016;428(9 Part A):1725–41.
    • (2016) J Mol Biol , vol.428 , Issue.9 Part A , pp. 1725-1741
    • Papinski, D.1    Kraft, C.2
  • 20
    • 79551598347 scopus 로고    scopus 로고
    • AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
    • COI: 1:CAS:528:DC%2BC3MXhtlamtb0%3D
    • Kim J, Kundu M, Viollet B, Guan KL. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol. 2011;13:132–41.
    • (2011) Nat Cell Biol , vol.13 , pp. 132-141
    • Kim, J.1    Kundu, M.2    Viollet, B.3    Guan, K.L.4
  • 21
    • 78650936005 scopus 로고    scopus 로고
    • The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression
    • COI: 1:CAS:528:DC%2BC3MXmslyk
    • Sun Q, Zhang J, Fan W, Wong KN, Ding X, Chen S, et al. The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression. J Biol Chem. 2011;286:185–91.
    • (2011) J Biol Chem , vol.286 , pp. 185-191
    • Sun, Q.1    Zhang, J.2    Fan, W.3    Wong, K.N.4    Ding, X.5    Chen, S.6
  • 22
    • 80054025654 scopus 로고    scopus 로고
    • The role of Atg proteins in autophagosome formation
    • COI: 1:CAS:528:DC%2BC3MXhsFyqtbnF
    • Mizushima N, Yoshimori T, Ohsumi Y. The role of Atg proteins in autophagosome formation. Annu Rev Cell Dev Biol. 2011;27:107–32.
    • (2011) Annu Rev Cell Dev Biol , vol.27 , pp. 107-132
    • Mizushima, N.1    Yoshimori, T.2    Ohsumi, Y.3
  • 23
    • 34548259958 scopus 로고    scopus 로고
    • p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    • COI: 1:CAS:528:DC%2BD2sXoslOntb0%3D
    • Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, et al. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem. 2007;282:24131–45.
    • (2007) J Biol Chem , vol.282 , pp. 24131-24145
    • Pankiv, S.1    Clausen, T.H.2    Lamark, T.3    Brech, A.4    Bruun, J.A.5    Outzen, H.6
  • 24
    • 0038819964 scopus 로고    scopus 로고
    • Erythroid gene suppression by NF-kappa B
    • COI: 1:CAS:528:DC%2BD3sXjvVSktLo%3D
    • Liu JJ, Hou SC, Shen CK. Erythroid gene suppression by NF-kappa B. J Biol Chem. 2003;278:19534–40.
    • (2003) J Biol Chem , vol.278 , pp. 19534-19540
    • Liu, J.J.1    Hou, S.C.2    Shen, C.K.3
  • 25
    • 4444341939 scopus 로고    scopus 로고
    • Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles
    • COI: 1:CAS:528:DC%2BD2cXotFaktLo%3D
    • Schneider-Brachert W, Tchikov V, Neumeyer J, Jakob M, Winoto-Morbach S, Held-Feindt J, et al. Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles. Immunity. 2004;21:415–28.
    • (2004) Immunity , vol.21 , pp. 415-428
    • Schneider-Brachert, W.1    Tchikov, V.2    Neumeyer, J.3    Jakob, M.4    Winoto-Morbach, S.5    Held-Feindt, J.6
  • 26
    • 0027183695 scopus 로고
    • Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor kappa B translocation in intact HL-60 cells
    • COI: 1:CAS:528:DyaK3sXltlOis7c%3D, PID: 8376408
    • Yang Z, Costanzo M, Golde DW, Kolesnick RN. Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor kappa B translocation in intact HL-60 cells. J Biol Chem. 1993;268:20520–3.
    • (1993) J Biol Chem , vol.268 , pp. 20520-20523
    • Yang, Z.1    Costanzo, M.2    Golde, D.W.3    Kolesnick, R.N.4
  • 27
    • 0026560014 scopus 로고
    • Tumor necrosis factor-alpha activates the sphingomyelin signal transduction pathway in a cell-free system
    • COI: 1:CAS:528:DyaK38XitFalt7c%3D
    • Dressler KA, Mathias S, Kolesnick RN. Tumor necrosis factor-alpha activates the sphingomyelin signal transduction pathway in a cell-free system. Science. 1992;255:1715–8.
    • (1992) Science , vol.255 , pp. 1715-1718
    • Dressler, K.A.1    Mathias, S.2    Kolesnick, R.N.3
  • 28
    • 0030595340 scopus 로고    scopus 로고
    • FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase
    • COI: 1:CAS:528:DyaK28XlvV2nsLs%3D
    • Adam-Klages S, Adam D, Wiegmann K, Struve S, Kolanus W, Schneider-Mergener J, et al. FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase. Cell. 1996;86:937–47.
    • (1996) Cell , vol.86 , pp. 937-947
    • Adam-Klages, S.1    Adam, D.2    Wiegmann, K.3    Struve, S.4    Kolanus, W.5    Schneider-Mergener, J.6
  • 29
    • 84901936622 scopus 로고    scopus 로고
    • Sphingolipid metabolites in inflammatory disease
    • COI: 1:CAS:528:DC%2BC2cXhtFygs77L
    • Maceyka M, Spiegel S. Sphingolipid metabolites in inflammatory disease. Nature. 2014;510:58–67.
    • (2014) Nature , vol.510 , pp. 58-67
    • Maceyka, M.1    Spiegel, S.2
  • 30
    • 84939979972 scopus 로고    scopus 로고
    • Autophagy in the light of sphingolipid metabolism
    • COI: 1:CAS:528:DC%2BC2MXivVSntr4%3D
    • Harvald EB, Olsen AS, Faergeman NJ. Autophagy in the light of sphingolipid metabolism. Apoptosis. 2015;20:658–70.
    • (2015) Apoptosis , vol.20 , pp. 658-670
    • Harvald, E.B.1    Olsen, A.S.2    Faergeman, N.J.3
  • 31
    • 84927913180 scopus 로고    scopus 로고
    • Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy
    • COI: 1:CAS:528:DC%2BC2MXksFWis7s%3D
    • Newton J, Lima S, Maceyka M, Spiegel S. Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy. Exp Cell Res. 2015;333:195–200.
    • (2015) Exp Cell Res , vol.333 , pp. 195-200
    • Newton, J.1    Lima, S.2    Maceyka, M.3    Spiegel, S.4
  • 32
    • 0033021394 scopus 로고    scopus 로고
    • Inhibition of human erythroid colony formation by ceramide
    • COI: 1:CAS:528:DyaK1MXktlSgsb0%3D
    • Dallalio G, North M, Worden BD, Means RT Jr. Inhibition of human erythroid colony formation by ceramide. Exp Hematol. 1999;27:1133–8.
    • (1999) Exp Hematol , vol.27 , pp. 1133-1138
    • Dallalio, G.1    North, M.2    Worden, B.D.3    Means, R.T.4
  • 33
    • 23044499360 scopus 로고    scopus 로고
    • Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development
    • COI: 1:CAS:528:DC%2BD2MXosVejsbg%3D
    • Muntean AG, Crispino JD. Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development. Blood. 2005;106:1223–31.
    • (2005) Blood , vol.106 , pp. 1223-1231
    • Muntean, A.G.1    Crispino, J.D.2
  • 34
    • 84938662340 scopus 로고    scopus 로고
    • Structural basis for ceramide recognition and hydrolysis by human neutral ceramidase
    • COI: 1:CAS:528:DC%2BC2MXhtF2ksL3L
    • Airola MV, Allen WJ, Pulkoski-Gross MJ, Obeid LM, Rizzo RC, Hannun YA. Structural basis for ceramide recognition and hydrolysis by human neutral ceramidase. Structure. 2015;23:1482–91.
    • (2015) Structure , vol.23 , pp. 1482-1491
    • Airola, M.V.1    Allen, W.J.2    Pulkoski-Gross, M.J.3    Obeid, L.M.4    Rizzo, R.C.5    Hannun, Y.A.6
  • 35
    • 0024795059 scopus 로고
    • Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation
    • COI: 1:CAS:528:DyaL1MXmtV2ksLY%3D, PID: 2808413
    • Okazaki T, Bell RM, Hannun YA. Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation. J Biol Chem. 1989;264:19076–80.
    • (1989) J Biol Chem , vol.264 , pp. 19076-19080
    • Okazaki, T.1    Bell, R.M.2    Hannun, Y.A.3
  • 36
    • 0026007737 scopus 로고
    • Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation
    • COI: 1:CAS:528:DyaK3MXpvFOitQ%3D%3D, PID: 1845977
    • Kim MY, Linardic C, Obeid L, Hannun Y. Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation. J Biol Chem. 1991;266:484–9.
    • (1991) J Biol Chem , vol.266 , pp. 484-489
    • Kim, M.Y.1    Linardic, C.2    Obeid, L.3    Hannun, Y.4
  • 37
    • 38049185075 scopus 로고    scopus 로고
    • Protein kinase B (c-akt) regulates hematopoietic lineage choice decisions during myelopoiesis
    • COI: 1:CAS:528:DC%2BD1cXjtVGruw%3D%3D
    • Buitenhuis M, Verhagen LP, van Deutekom HW, Castor A, Verploegen S, Koenderman L, et al. Protein kinase B (c-akt) regulates hematopoietic lineage choice decisions during myelopoiesis. Blood. 2008;111:112–21.
    • (2008) Blood , vol.111 , pp. 112-121
    • Buitenhuis, M.1    Verhagen, L.P.2    van Deutekom, H.W.3    Castor, A.4    Verploegen, S.5    Koenderman, L.6
  • 38
    • 84878399926 scopus 로고    scopus 로고
    • G-CSF activation of AKT is not sufficient to prolong neutrophil survival
    • COI: 1:CAS:528:DC%2BC3sXptlOjsr0%3D
    • Souza LR, Silva E, Calloway E, Cabrera C, McLemore ML. G-CSF activation of AKT is not sufficient to prolong neutrophil survival. J Leukoc Biol. 2013;93:883–93.
    • (2013) J Leukoc Biol , vol.93 , pp. 883-893
    • Souza, L.R.1    Silva, E.2    Calloway, E.3    Cabrera, C.4    McLemore, M.L.5
  • 39
    • 77954955537 scopus 로고    scopus 로고
    • The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis
    • COI: 1:CAS:528:DC%2BC3cXptVCktro%3D
    • Martelli AM, Evangelisti C, Chiarini F, Grimaldi C, Cappellini A, Ognibene A, et al. The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis. Biochim Biophys Acta. 2010;1803:991–1002.
    • (2010) Biochim Biophys Acta , vol.1803 , pp. 991-1002
    • Martelli, A.M.1    Evangelisti, C.2    Chiarini, F.3    Grimaldi, C.4    Cappellini, A.5    Ognibene, A.6
  • 40
    • 85027937046 scopus 로고    scopus 로고
    • p62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells
    • COI: 1:CAS:528:DC%2BC2cXht1WlsrnM
    • Trocoli A, Bensadoun P, Richard E, Labrunie G, Merhi F, Schlafli AM, et al. p62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells. Cell Death Differ. 2014;21:1852–61.
    • (2014) Cell Death Differ , vol.21 , pp. 1852-1861
    • Trocoli, A.1    Bensadoun, P.2    Richard, E.3    Labrunie, G.4    Merhi, F.5    Schlafli, A.M.6
  • 41
    • 77952782911 scopus 로고    scopus 로고
    • PU.1 positively regulates GATA-1 expression in mast cells
    • COI: 1:CAS:528:DC%2BC3cXkt1Wqt7c%3D
    • Takemoto CM, Brandal S, Jegga AG, Lee YN, Shahlaee A, Ying Y, et al. PU.1 positively regulates GATA-1 expression in mast cells. J Immunol. 2010;184:4349–61.
    • (2010) J Immunol , vol.184 , pp. 4349-4361
    • Takemoto, C.M.1    Brandal, S.2    Jegga, A.G.3    Lee, Y.N.4    Shahlaee, A.5    Ying, Y.6
  • 42
    • 0036435483 scopus 로고    scopus 로고
    • Roles of hematopoietic transcription factors GATA-1 and GATA-2 in the development of red blood cell lineage
    • COI: 1:CAS:528:DC%2BD38XoslCjsbs%3D
    • Ohneda K, Yamamoto M. Roles of hematopoietic transcription factors GATA-1 and GATA-2 in the development of red blood cell lineage. Acta Haematol. 2002;108:237–45.
    • (2002) Acta Haematol , vol.108 , pp. 237-245
    • Ohneda, K.1    Yamamoto, M.2
  • 43
    • 11244251722 scopus 로고    scopus 로고
    • Interplay of pu.1 and gata1 determines myelo-erythroid progenitor cell fate in zebrafish
    • COI: 1:CAS:528:DC%2BD2MXot1Cmsg%3D%3D
    • Rhodes J, Hagen A, Hsu K, Deng M, Liu TX, Look AT, et al. Interplay of pu.1 and gata1 determines myelo-erythroid progenitor cell fate in zebrafish. Dev Cell. 2005;8:97–108.
    • (2005) Dev Cell , vol.8 , pp. 97-108
    • Rhodes, J.1    Hagen, A.2    Hsu, K.3    Deng, M.4    Liu, T.X.5    Look, A.T.6
  • 44
    • 17544400277 scopus 로고    scopus 로고
    • An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells
    • COI: 1:CAS:528:DC%2BD3cXmtFegtLs%3D
    • Whyatt D, Lindeboom F, Karis A, Ferreira R, Milot E, Hendriks R, et al. An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells. Nature. 2000;406:519–24.
    • (2000) Nature , vol.406 , pp. 519-524
    • Whyatt, D.1    Lindeboom, F.2    Karis, A.3    Ferreira, R.4    Milot, E.5    Hendriks, R.6
  • 45
    • 0034739815 scopus 로고    scopus 로고
    • Levels of GATA-1/GATA-2 transcription factors modulate expression of embryonic and fetal hemoglobins
    • COI: 1:CAS:528:DC%2BD3MXovFWruw%3D%3D
    • Ikonomi P, Noguchi CT, Miller W, Kassahun H, Hardison R, Schechter AN. Levels of GATA-1/GATA-2 transcription factors modulate expression of embryonic and fetal hemoglobins. Gene. 2000;261:277–87.
    • (2000) Gene , vol.261 , pp. 277-287
    • Ikonomi, P.1    Noguchi, C.T.2    Miller, W.3    Kassahun, H.4    Hardison, R.5    Schechter, A.N.6
  • 46
    • 27744587735 scopus 로고    scopus 로고
    • PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure
    • COI: 1:CAS:528:DC%2BD2MXhtFKktrbP
    • Stopka T, Amanatullah DF, Papetti M, Skoultchi AI. PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure. EMBO J. 2005;24:3712–23.
    • (2005) EMBO J , vol.24 , pp. 3712-3723
    • Stopka, T.1    Amanatullah, D.F.2    Papetti, M.3    Skoultchi, A.I.4
  • 47
    • 0035871848 scopus 로고    scopus 로고
    • Lineage switch induced by overexpression of Ets family transcription factor PU.1 in murine erythroleukemia cells
    • COI: 1:CAS:528:DC%2BD3MXivFOgtL4%3D
    • Yamada T, Abe M, Higashi T, Yamamoto H, Kihara-Negishi F, Sakurai T, et al. Lineage switch induced by overexpression of Ets family transcription factor PU.1 in murine erythroleukemia cells. Blood. 2001;97:2300–7.
    • (2001) Blood , vol.97 , pp. 2300-2307
    • Yamada, T.1    Abe, M.2    Higashi, T.3    Yamamoto, H.4    Kihara-Negishi, F.5    Sakurai, T.6
  • 48
    • 66349138750 scopus 로고    scopus 로고
    • MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis
    • COI: 1:CAS:528:DC%2BD1MXpsFegt7o%3D
    • Felli N, Pedini F, Romania P, Biffoni M, Morsilli O, Castelli G, et al. MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis. Haematologica. 2009;94:479–86.
    • (2009) Haematologica , vol.94 , pp. 479-486
    • Felli, N.1    Pedini, F.2    Romania, P.3    Biffoni, M.4    Morsilli, O.5    Castelli, G.6
  • 50
    • 35648960257 scopus 로고    scopus 로고
    • Expression patterns of microRNAs 155 and 451 during normal human erythropoiesis
    • COI: 1:CAS:528:DC%2BD2sXht1Krur7E
    • Masaki S, Ohtsuka R, Abe Y, Muta K, Umemura T. Expression patterns of microRNAs 155 and 451 during normal human erythropoiesis. Biochem Biophys Res Commun. 2007;364:509–14.
    • (2007) Biochem Biophys Res Commun , vol.364 , pp. 509-514
    • Masaki, S.1    Ohtsuka, R.2    Abe, Y.3    Muta, K.4    Umemura, T.5
  • 51
    • 67650230871 scopus 로고    scopus 로고
    • Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation
    • COI: 1:CAS:528:DC%2BD1MXhtVOkurvJ, PID: 19417210
    • Zhang J, Randall MS, Loyd MR, Dorsey FC, Kundu M, Cleveland JL, et al. Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation. Blood. 2009;114:157–64.
    • (2009) Blood , vol.114 , pp. 157-164
    • Zhang, J.1    Randall, M.S.2    Loyd, M.R.3    Dorsey, F.C.4    Kundu, M.5    Cleveland, J.L.6
  • 52
    • 51649124519 scopus 로고    scopus 로고
    • Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
    • COI: 1:CAS:528:DC%2BD1cXpvVOkur4%3D
    • Kundu M, Lindsten T, Yang CY, Wu J, Zhao F, Zhang J, et al. Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation. Blood. 2008;112:1493–502.
    • (2008) Blood , vol.112 , pp. 1493-1502
    • Kundu, M.1    Lindsten, T.2    Yang, C.Y.3    Wu, J.4    Zhao, F.5    Zhang, J.6
  • 53
    • 47049100413 scopus 로고    scopus 로고
    • Essential role for Nix in autophagic maturation of erythroid cells
    • COI: 1:CAS:528:DC%2BD1cXot1ygsrg%3D
    • Sandoval H, Thiagarajan P, Dasgupta SK, Schumacher A, Prchal JT, Chen M, et al. Essential role for Nix in autophagic maturation of erythroid cells. Nature. 2008;454:232–5.
    • (2008) Nature , vol.454 , pp. 232-235
    • Sandoval, H.1    Thiagarajan, P.2    Dasgupta, S.K.3    Schumacher, A.4    Prchal, J.T.5    Chen, M.6
  • 54
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • COI: 1:CAS:528:DC%2BC3cXlt1KlsLc%3D
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell. 2010;140:313–26.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 55
    • 47249125723 scopus 로고    scopus 로고
    • Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt
    • COI: 1:CAS:528:DC%2BD1cXmtVams74%3D
    • Dan HC, Baldwin AS. Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt. J Immunol. 2008;180:7582–9.
    • (2008) J Immunol , vol.180 , pp. 7582-7589
    • Dan, H.C.1    Baldwin, A.S.2
  • 56
    • 85009895031 scopus 로고    scopus 로고
    • Inhibition of autophagic degradation process contributes to claudin-2 expression increase and epithelial tight junction dysfunction in TNF-alpha treated cell monolayers
    • Zhang C, Yan J, Xiao Y, Shen Y, Wang J, Ge W, et al. Inhibition of autophagic degradation process contributes to claudin-2 expression increase and epithelial tight junction dysfunction in TNF-alpha treated cell monolayers. Int J Mol Sci. 2017;18. pii: E157
    • (2017) Int J Mol Sci , vol.18
    • Zhang, C.1    Yan, J.2    Xiao, Y.3    Shen, Y.4    Wang, J.5    Ge, W.6
  • 57
    • 84954129051 scopus 로고    scopus 로고
    • p62/SQSTM1 functions as a signaling hub and an autophagy adaptor
    • COI: 1:CAS:528:DC%2BC2MXhs1KisbbO
    • Katsuragi Y, Ichimura Y, Komatsu M. p62/SQSTM1 functions as a signaling hub and an autophagy adaptor. FEBS J. 2015;282:4672–8.
    • (2015) FEBS J , vol.282 , pp. 4672-4678
    • Katsuragi, Y.1    Ichimura, Y.2    Komatsu, M.3
  • 58
    • 2542475112 scopus 로고    scopus 로고
    • Caspase-3 has a nonapoptotic function in erythroid maturation
    • COI: 1:CAS:528:DC%2BD2cXkvVyitb4%3D
    • Carlile GW, Smith DH, Wiedmann M. Caspase-3 has a nonapoptotic function in erythroid maturation. Blood. 2004;103:4310–6.
    • (2004) Blood , vol.103 , pp. 4310-4316
    • Carlile, G.W.1    Smith, D.H.2    Wiedmann, M.3
  • 59
    • 0023320241 scopus 로고
    • Two procedures to remove polar contaminants from a crude brain lipid extract by using prepacked reversed-phase columns
    • COI: 1:CAS:528:DyaL2sXktVemsL0%3D
    • Kyrklund T. Two procedures to remove polar contaminants from a crude brain lipid extract by using prepacked reversed-phase columns. Lipids. 1987;22:274–7.
    • (1987) Lipids , vol.22 , pp. 274-277
    • Kyrklund, T.1
  • 60
    • 84908333211 scopus 로고    scopus 로고
    • Valproic acid regulates erythro-megakaryocytic differentiation through the modulation of transcription factors and microRNA regulatory micro-networks
    • COI: 1:CAS:528:DC%2BC2cXhs1Shs7jF
    • Trecul A, Morceau F, Gaigneaux A, Schnekenburger M, Dicato M, Diederich M. Valproic acid regulates erythro-megakaryocytic differentiation through the modulation of transcription factors and microRNA regulatory micro-networks. Biochem Pharmacol. 2014;92:299–311.
    • (2014) Biochem Pharmacol , vol.92 , pp. 299-311
    • Trecul, A.1    Morceau, F.2    Gaigneaux, A.3    Schnekenburger, M.4    Dicato, M.5    Diederich, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.