Valproic acid regulates erythro-megakaryocytic differentiation through the modulation of transcription factors and microRNA regulatory micro-networks

Biochemical Pharmacology

Volumn 92, Issue 2, 2014, Pages 299-311

  Trécul, Anne ^a   Morceau, Franck ^a   Gaigneaux, Anthoula ^a   Schnekenburger, Michael ^a   Dicato, Mario ^a   Diederich, Marc ^b  

^a LABORATOIRE DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE DU CANCER   (Luxembourg)

^b Seoul National University   (South Korea)

Author keywords

GATA 1; Hematopoietic differentiation; miR 144 451; Valproic acid

Indexed keywords

ACLACINOMYCIN; BETA3 INTEGRIN; CD34 ANTIGEN; ENTINOSTAT; GA BINDING PROTEIN; MESSENGER RNA; MICRORNA; MICRORNA 155; RECOMBINANT ERYTHROPOIETIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR FLI 1; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR PU 1; TRANSCRIPTION FACTOR RUNX1; VALPROIC ACID; VALPROMIDE;

ARTICLE; CELL DIFFERENTIATION; CELL STRUCTURE; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; ERYTHROID CELL; ERYTHROPOIESIS; GENE EXPRESSION; GENE REGULATORY NETWORK; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; K562 CELL LINE; LEUKEMIA CELL; MEGAKARYOCYTE; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; CYTOLOGY; DRUG EFFECTS; FETUS BLOOD; PHYSIOLOGY;

CELL DIFFERENTIATION; ERYTHROID CELLS; FETAL BLOOD; HEMATOPOIETIC STEM CELLS; HUMANS; K562 CELLS; MEGAKARYOCYTES; MICRORNAS; TRANSCRIPTION FACTORS; VALPROIC ACID;

EID: 84908333211     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.07.035     Document Type: Article

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