-
1
-
-
84953297153
-
Organoids as a model system for studying human lung development and disease
-
Nadkarni RR, Abed S, Draper JS (2016) Organoids as a model system for studying human lung development and disease. Biochem Biophys Res Commun 473:675–682. doi:10.1016/j.bbrc.2015.12.091
-
(2016)
Biochem Biophys Res Commun
, vol.473
, pp. 675-682
-
-
Nadkarni, R.R.1
Abed, S.2
Draper, J.S.3
-
2
-
-
84975275212
-
Modeling development and disease with organoids
-
Clevers H (2016) Modeling development and disease with organoids. Cell 165:1586–1597. doi:10.1016/j.cell.2016.05.082
-
(2016)
Cell
, vol.165
, pp. 1586-1597
-
-
Clevers, H.1
-
3
-
-
67349123408
-
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
-
Sato T, Vries RG, Snippert HJ et al (2009) Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459:262–265. doi:10.1038/nature07935
-
(2009)
Nature
, vol.459
, pp. 262-265
-
-
Sato, T.1
Vries, R.G.2
Snippert, H.J.3
-
4
-
-
78751644734
-
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
-
Sato T, van Es JH, Snippert HJ et al (2011) Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Nature 469:415–418. doi:10.1038/nature09637
-
(2011)
Nature
, vol.469
, pp. 415-418
-
-
Sato, T.1
van Es, J.H.2
Snippert, H.J.3
-
5
-
-
73049116186
-
Lgr5+ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro
-
Barker N, Huch M, Kujala P et al (2010) Lgr5+ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 6:25–36. doi:10.1016/j.stem.2009.11.013
-
(2010)
Cell Stem Cell
, vol.6
, pp. 25-36
-
-
Barker, N.1
Huch, M.2
Kujala, P.3
-
6
-
-
78751644734
-
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
-
Sato T, van Es JH, Snippert HJ et al (2011) Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Nature 469:415–418. doi:10.1038/nature09637
-
(2011)
Nature
, vol.469
, pp. 415-418
-
-
Sato, T.1
van Es, J.H.2
Snippert, H.J.3
-
7
-
-
80054857419
-
Long-term expansion of epithelial organoids from human Colon, adenoma, adenocarcinoma, and Barrett’s epithelium
-
Sato T, Stange DE, Ferrante M et al (2011) Long-term expansion of epithelial organoids from human Colon, adenoma, adenocarcinoma, and Barrett’s epithelium. Gastroenterology 141:1762–1772. doi:10.1053/j.gastro.2011.07.050
-
(2011)
Gastroenterology
, vol.141
, pp. 1762-1772
-
-
Sato, T.1
Stange, D.E.2
Ferrante, M.3
-
8
-
-
84885846800
-
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis
-
Huch M, Bonfanti P, Boj SF et al (2013) Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis. EMBO J 32:2708–2721. doi:10.1038/emboj.2013.204
-
(2013)
EMBO J
, vol.32
, pp. 2708-2721
-
-
Huch, M.1
Bonfanti, P.2
Boj, S.F.3
-
9
-
-
84873712443
-
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
-
Huch M, Dorrell C, Boj SF et al (2013) In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration. Nature 494:247–250. doi:10.1038/nature11826
-
(2013)
Nature
, vol.494
, pp. 247-250
-
-
Huch, M.1
Dorrell, C.2
Boj, S.F.3
-
10
-
-
84907552531
-
Identification of multipotent luminal progenitor cells in human prostate organoid cultures
-
Karthaus WR, Iaquinta PJ, Drost J et al (2014) Identification of multipotent luminal progenitor cells in human prostate organoid cultures. Cell 159:163–175. doi:10.1016/j.cell.2014.08.017
-
(2014)
Cell
, vol.159
, pp. 163-175
-
-
Karthaus, W.R.1
Iaquinta, P.J.2
Drost, J.3
-
11
-
-
84894623720
-
Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny
-
Yin X, Farin HF, van Es JH et al (2014) Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny. Nat Methods 11:106–112. doi:10.1038/nmeth.2737
-
(2014)
Nat Methods
, vol.11
, pp. 106-112
-
-
Yin, X.1
Farin, H.F.2
van Es, J.H.3
-
13
-
-
84920989984
-
Long-term culture of genome-stable bipotent stem cells from adult human liver
-
Huch M, Gehart H, van Boxtel R et al (2015) Long-term culture of genome-stable bipotent stem cells from adult human liver. Cell 160:299–312. doi:10.1016/j.cell.2014.11.050
-
(2015)
Cell
, vol.160
, pp. 299-312
-
-
Huch, M.1
Gehart, H.2
van Boxtel, R.3
-
14
-
-
85014751112
-
Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation
-
Broutier L, Andersson-Rolf A, Hindley CJ et al (2016) Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation. Nat Protoc 11:1724–1743. doi:10.1038/nprot.2016.097
-
(2016)
Nat Protoc
, vol.11
, pp. 1724-1743
-
-
Broutier, L.1
Andersson-Rolf, A.2
Hindley, C.J.3
-
15
-
-
84885617460
-
Artificial three-dimensional niches deconstruct pancreas development in vitro
-
Greggio C, De Franceschi F, Figueiredo-Larsen M et al (2013) Artificial three-dimensional niches deconstruct pancreas development in vitro. Development 140:4452–4462. doi:10.1242/dev.096628
-
(2013)
Development
, vol.140
, pp. 4452-4462
-
-
Greggio, C.1
De Franceschi, F.2
Figueiredo-Larsen, M.3
-
16
-
-
84919431170
-
Concise reviews: in vitro-produced pancreas organogenesis models in three dimensions: self-organization from few stem cells or progenitors
-
Greggio C, De Franceschi F, Grapin-Botton A (2015) Concise reviews: in vitro-produced pancreas organogenesis models in three dimensions: self-organization from few stem cells or progenitors. Stem Cells 33:8–14. doi:10.1002/stem.1828
-
(2015)
Stem Cells
, vol.33
, pp. 8-14
-
-
Greggio, C.1
De Franceschi, F.2
Grapin-Botton, A.3
-
17
-
-
84991834394
-
Lung epithelial tip progenitors integrate glucocorticoid and STAT3-mediated signals to control progeny fate
-
Laresgoiti U, Nikolić MZ, Rao C et al (2016) Lung epithelial tip progenitors integrate glucocorticoid and STAT3-mediated signals to control progeny fate. Development. doi:10.1242/dev.134023
-
(2016)
Development
-
-
Laresgoiti, U.1
Nikolić, M.Z.2
Rao, C.3
-
18
-
-
0035694459
-
Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis
-
COI: 1:CAS:528:DC%2BD38XnvVWjtw%3D%3D, PID: 11748146
-
Bhushan A, Itoh N, Kato S et al (2001) Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development 128:5109–5117
-
(2001)
Development
, vol.128
, pp. 5109-5117
-
-
Bhushan, A.1
Itoh, N.2
Kato, S.3
-
19
-
-
0024240796
-
A community effect in animal development
-
Gurdon JB (1988) A community effect in animal development. Nature 336:772–774. doi:10.1038/336772a0
-
(1988)
Nature
, vol.336
, pp. 772-774
-
-
Gurdon, J.B.1
-
22
-
-
84896085395
-
Single primary fetal lung cells generate alveolar structures in vitro
-
Zhang S, Zhou X, Chen T et al (2014) Single primary fetal lung cells generate alveolar structures in vitro. In Vitro Cell Dev Biol Anim 50:87–93. doi:10.1007/s11626-013-9657-6
-
(2014)
In Vitro Cell Dev Biol Anim
, vol.50
, pp. 87-93
-
-
Zhang, S.1
Zhou, X.2
Chen, T.3
-
23
-
-
84984640140
-
A three-dimensional human model of the fibroblast activation that accompanies bronchopulmonary dysplasia identifies Notch-mediated pathophysiology
-
Sucre JMS, Wilkinson D, Vijayaraj P et al (2016) A three-dimensional human model of the fibroblast activation that accompanies bronchopulmonary dysplasia identifies Notch-mediated pathophysiology. Am J Physiol Lung Cell Mol Physiol 310:L889–L898. doi:10.1152/ajplung.00446.2015
-
(2016)
Am J Physiol Lung Cell Mol Physiol
, vol.310
, pp. L889-L898
-
-
Sucre, J.M.S.1
Wilkinson, D.2
Vijayaraj, P.3
-
24
-
-
85017617797
-
Development of a three-dimensional bioengineering technology to generate lung tissue for personalized disease modeling
-
Wilkinson DC, Alva-Ornelas JA, Sucre JMS et al (2016) Development of a three-dimensional bioengineering technology to generate lung tissue for personalized disease modeling. Stem Cells Transl Med. doi:10.5966/sctm.2016-0192
-
(2016)
Stem Cells Transl Med
-
-
Wilkinson, D.C.1
Alva-Ornelas, J.A.2
Sucre, J.M.S.3
-
25
-
-
69149106207
-
Basal cells as stem cells of the mouse trachea and human airway epithelium
-
Rock JR, Onaitis MW, Rawlins EL et al (2009) Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc Natl Acad Sci U S A 106:12771–12775. doi:10.1073/pnas.0906850106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12771-12775
-
-
Rock, J.R.1
Onaitis, M.W.2
Rawlins, E.L.3
-
26
-
-
79957797173
-
Notch-dependent differentiation of adult airway basal stem cells
-
Rock JR, Gao X, Xue Y et al (2011) Notch-dependent differentiation of adult airway basal stem cells. Cell Stem Cell 8:639–648. doi:10.1016/j.stem.2011.04.003
-
(2011)
Cell Stem Cell
, vol.8
, pp. 639-648
-
-
Rock, J.R.1
Gao, X.2
Xue, Y.3
-
27
-
-
84893436164
-
Lung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis
-
This paper uses a co-culture-based organoid system to dissect the detailed molecular interactions between a putative lung epithelial stem cell population and its endothelial cell niche
-
•• Lee J-H, Bhang DH, Beede A et al (2014) Lung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis. Cell 156:440–455. doi:10.1016/j.cell.2013.12.039 This paper uses a co-culture-based organoid system to dissect the detailed molecular interactions between a putative lung epithelial stem cell population and its endothelial cell niche
-
(2014)
Cell
, vol.156
, pp. 440-455
-
-
Lee, J.-H.1
Bhang, D.H.2
Beede, A.3
-
28
-
-
84879640376
-
Type 2 alveolar cells are stem cells in adult lung
-
Barkauskas CE, Cronce MJ, Rackley CR et al (2013) Type 2 alveolar cells are stem cells in adult lung. J Clin Invest 123:3025–3036. doi:10.1172/JCI68782
-
(2013)
J Clin Invest
, vol.123
, pp. 3025-3036
-
-
Barkauskas, C.E.1
Cronce, M.J.2
Rackley, C.R.3
-
29
-
-
84913587019
-
Generation of alveolar epithelial spheroids via isolated progenitor cells from human pluripotent stem cells
-
Gotoh S, Ito I, Nagasaki T et al (2014) Generation of alveolar epithelial spheroids via isolated progenitor cells from human pluripotent stem cells. Stem Cell Reports 3:394–403. doi:10.1016/j.stemcr.2014.07.005
-
(2014)
Stem Cell Reports
, vol.3
, pp. 394-403
-
-
Gotoh, S.1
Ito, I.2
Nagasaki, T.3
-
30
-
-
84955397469
-
Directed induction of functional multi-ciliated cells in proximal airway epithelial spheroids from human pluripotent stem cells
-
Konishi S, Gotoh S, Tateishi K et al (2016) Directed induction of functional multi-ciliated cells in proximal airway epithelial spheroids from human pluripotent stem cells. Stem Cell Reports 6:18–25. doi:10.1016/j.stemcr.2015.11.010
-
(2016)
Stem Cell Reports
, vol.6
, pp. 18-25
-
-
Konishi, S.1
Gotoh, S.2
Tateishi, K.3
-
31
-
-
84925459906
-
In vitro generation of human pluripotent stem cell derived lung organoids
-
Describes the development of lung organoids containing both bronchiolar and alveolar regions and associated mesenchyme derived from pluripotent stem cells
-
•• Dye BR, Hill DR, Ferguson MAH et al (2015) In vitro generation of human pluripotent stem cell derived lung organoids. elife. doi:10.7554/eLife.05098 Describes the development of lung organoids containing both bronchiolar and alveolar regions and associated mesenchyme derived from pluripotent stem cells
-
(2015)
elife
-
-
Dye, B.R.1
Hill, D.R.2
Ferguson, M.A.H.3
-
33
-
-
84905869926
-
Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function
-
Hogan BLM, Barkauskas CE, Chapman HA et al (2014) Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function. Cell Stem Cell 15:123–138. doi:10.1016/j.stem.2014.07.012
-
(2014)
Cell Stem Cell
, vol.15
, pp. 123-138
-
-
Hogan, B.L.M.1
Barkauskas, C.E.2
Chapman, H.A.3
-
34
-
-
74049139927
-
Preparing for the first breath: genetic and cellular mechanisms in lung development
-
Morrisey EE, Hogan BLM (2010) Preparing for the first breath: genetic and cellular mechanisms in lung development. Dev Cell 18:8–23. doi:10.1016/j.devcel.2009.12.010
-
(2010)
Dev Cell
, vol.18
, pp. 8-23
-
-
Morrisey, E.E.1
Hogan, B.L.M.2
-
36
-
-
0031862237
-
Number and proliferation of basal and parabasal cells in normal human airway epithelium
-
Boers JE, Ambergen AW, Thunnissen FB (1998) Number and proliferation of basal and parabasal cells in normal human airway epithelium. Am J Respir Crit Care Med 157:2000–2006. doi:10.1164/ajrccm.157.6.9707011
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 2000-2006
-
-
Boers, J.E.1
Ambergen, A.W.2
Thunnissen, F.B.3
-
37
-
-
0032440058
-
Immunohistochemical and ultrastructural studies of basal cells, Clara cells and bronchiolar cuboidal cells in normal human airways
-
COI: 1:STN:280:DyaK1M7jsFyjuw%3D%3D, PID: 9952338
-
Nakajima M, Kawanami O, Jin E et al (1998) Immunohistochemical and ultrastructural studies of basal cells, Clara cells and bronchiolar cuboidal cells in normal human airways. Pathol Int 48:944–953
-
(1998)
Pathol Int
, vol.48
, pp. 944-953
-
-
Nakajima, M.1
Kawanami, O.2
Jin, E.3
-
38
-
-
0038041946
-
Alveolar type I cells: molecular phenotype and development
-
Williams MC (2003) Alveolar type I cells: molecular phenotype and development. Annu Rev Physiol 65:669–695. doi:10.1146/annurev.physiol.65.092101.142446
-
(2003)
Annu Rev Physiol
, vol.65
, pp. 669-695
-
-
Williams, M.C.1
-
39
-
-
50849098529
-
Knowns and unknowns of the alveolus
-
Herzog EL, Brody AR, Colby TV et al (2008) Knowns and unknowns of the alveolus. Proc Am Thorac Soc 5:778–782. doi:10.1513/pats.200803-028HR
-
(2008)
Proc Am Thorac Soc
, vol.5
, pp. 778-782
-
-
Herzog, E.L.1
Brody, A.R.2
Colby, T.V.3
-
40
-
-
84923902446
-
On the tricks alveolar epithelial cells play to make a good lung
-
Weibel ER (2015) On the tricks alveolar epithelial cells play to make a good lung. Am J Respir Crit Care Med 191:504–513. doi:10.1164/rccm.201409-1663OE
-
(2015)
Am J Respir Crit Care Med
, vol.191
, pp. 504-513
-
-
Weibel, E.R.1
-
41
-
-
0019977498
-
Cell number and cell characteristics of the normal human lung
-
Crapo JD, Barry BE, Gehr P et al (1982) Cell number and cell characteristics of the normal human lung. Am Rev Respir Dis 126:332–337. doi:10.1164/arrd.1982.126.2.332
-
(1982)
Am Rev Respir Dis
, vol.126
, pp. 332-337
-
-
Crapo, J.D.1
Barry, B.E.2
Gehr, P.3
-
42
-
-
84925283050
-
The development and function of lung-resident macrophages and dendritic cells
-
Kopf M, Schneider C, Nobs SP (2015) The development and function of lung-resident macrophages and dendritic cells. Nat Immunol 16:36–44. doi:10.1038/ni.3052
-
(2015)
Nat Immunol
, vol.16
, pp. 36-44
-
-
Kopf, M.1
Schneider, C.2
Nobs, S.P.3
-
43
-
-
84924942801
-
The pulmonary mesenchyme directs lung development
-
McCulley D, Wienhold M, Sun X (2015) The pulmonary mesenchyme directs lung development. Curr Opin Genet Dev 32:98–105. doi:10.1016/j.gde.2015.01.011
-
(2015)
Curr Opin Genet Dev
, vol.32
, pp. 98-105
-
-
McCulley, D.1
Wienhold, M.2
Sun, X.3
-
44
-
-
84994584920
-
A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids
-
Dye BR, Dedhia PH, Miller AJ et al (2016) A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids. elife 5:e19732. doi:10.7554/eLife.19732
-
(2016)
elife
, vol.5
-
-
Dye, B.R.1
Dedhia, P.H.2
Miller, A.J.3
-
45
-
-
84930193758
-
Mimicking the niche of lung epithelial stem cells and characterization of several effectors of their in vitro behavior
-
Hegab AE, Arai D, Gao J et al (2015) Mimicking the niche of lung epithelial stem cells and characterization of several effectors of their in vitro behavior. Stem Cell Res 15:109–121. doi:10.1016/j.scr.2015.05.005
-
(2015)
Stem Cell Res
, vol.15
, pp. 109-121
-
-
Hegab, A.E.1
Arai, D.2
Gao, J.3
-
46
-
-
84978849136
-
Influenza virus infects epithelial stem/progenitor cells of the distal lung: impact on Fgfr2b-driven epithelial repair
-
Quantius J, Schmoldt C, Vazquez-Armendariz AI et al (2016) Influenza virus infects epithelial stem/progenitor cells of the distal lung: impact on Fgfr2b-driven epithelial repair. PLoS Pathog 12:e1005544. doi:10.1371/journal.ppat.1005544
-
(2016)
PLoS Pathog
, vol.12
-
-
Quantius, J.1
Schmoldt, C.2
Vazquez-Armendariz, A.I.3
-
47
-
-
84892748994
-
Lung development: orchestrating the generation and regeneration of a complex organ
-
Herriges M, Morrisey EE (2014) Lung development: orchestrating the generation and regeneration of a complex organ. Development 141:502–513. doi:10.1242/dev.098186
-
(2014)
Development
, vol.141
, pp. 502-513
-
-
Herriges, M.1
Morrisey, E.E.2
-
48
-
-
13444310931
-
Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung
-
Serls AE, Doherty S, Parvatiyar P et al (2005) Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung. Development 132:35–47. doi:10.1242/dev.01570
-
(2005)
Development
, vol.132
, pp. 35-47
-
-
Serls, A.E.1
Doherty, S.2
Parvatiyar, P.3
-
49
-
-
70450196056
-
The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells
-
Rawlins EL, Clark CP, Xue Y, Hogan BLM (2009) The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells. Development 136:3741–3745. doi:10.1242/dev.037317
-
(2009)
Development
, vol.136
, pp. 3741-3745
-
-
Rawlins, E.L.1
Clark, C.P.2
Xue, Y.3
Hogan, B.L.M.4
-
50
-
-
84901785603
-
Two nested developmental waves demarcate a compartment boundary in the mouse lung
-
Alanis DM, Chang DR, Akiyama H et al (2014) Two nested developmental waves demarcate a compartment boundary in the mouse lung. Nat Commun 5:3923. doi:10.1038/ncomms4923
-
(2014)
Nat Commun
, vol.5
, pp. 3923
-
-
Alanis, D.M.1
Chang, D.R.2
Akiyama, H.3
-
51
-
-
84896319764
-
Alveolar progenitor and stem cells in lung development, renewal and cancer
-
Desai TJ, Brownfield DG, Krasnow MA. Alveolar progenitor and stem cells in lung development, renewal and cancer. Nature. 2014: 1–16. doi: 10.1038/nature12930
-
(2014)
Nature
, pp. 1-16
-
-
Desai, T.J.1
Brownfield, D.G.2
Krasnow, M.A.3
-
52
-
-
77952999989
-
Explant culture of mouse embryonic whole lung, isolated epithelium, or mesenchyme under chemically defined conditions as a system to evaluate the molecular mechanism of branching morphogenesis and cellular differentiation
-
del Moral P-M, Warburton D (2010) Explant culture of mouse embryonic whole lung, isolated epithelium, or mesenchyme under chemically defined conditions as a system to evaluate the molecular mechanism of branching morphogenesis and cellular differentiation. Methods Mol Biol 633:71–79. doi:10.1007/978-1-59745-019-5_5
-
(2010)
Methods Mol Biol
, vol.633
, pp. 71-79
-
-
del Moral, P.-M.1
Warburton, D.2
-
53
-
-
0027177516
-
Role of epidermal growth factor expression in early mouse embryo lung branching morphogenesis in culture: antisense oligodeoxynucleotide inhibitory strategy
-
Seth R, Shum L, Wu F et al (1993) Role of epidermal growth factor expression in early mouse embryo lung branching morphogenesis in culture: antisense oligodeoxynucleotide inhibitory strategy. Dev Biol 158:555–559. doi:10.1006/dbio.1993.1213
-
(1993)
Dev Biol
, vol.158
, pp. 555-559
-
-
Seth, R.1
Shum, L.2
Wu, F.3
-
54
-
-
0023908071
-
Embryonic mouse lung morphogenesis and type II cytodifferentiation in serumless, chemically defined medium using prolonged in vitro cultures
-
COI: 1:CAS:528:DyaL1cXkslWjsr8%3D, PID: 3061659
-
Jaskoll TF, Don-Wheeler G, Johnson R, Slavkin HC (1988) Embryonic mouse lung morphogenesis and type II cytodifferentiation in serumless, chemically defined medium using prolonged in vitro cultures. Cell Differ 24:105–117
-
(1988)
Cell Differ
, vol.24
, pp. 105-117
-
-
Jaskoll, T.F.1
Don-Wheeler, G.2
Johnson, R.3
Slavkin, H.C.4
-
55
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663–676. doi:10.1016/j.cell.2006.07.024
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
56
-
-
84859551885
-
Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells
-
Longmire TA, Ikonomou L, Hawkins F et al (2012) Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells. Cell Stem Cell 10:398–411. doi:10.1016/j.stem.2012.01.019
-
(2012)
Cell Stem Cell
, vol.10
, pp. 398-411
-
-
Longmire, T.A.1
Ikonomou, L.2
Hawkins, F.3
-
57
-
-
84859557287
-
Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs
-
Mou H, Zhao R, Sherwood R et al (2012) Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs. Cell Stem Cell 10:385–397. doi:10.1016/j.stem.2012.01.018
-
(2012)
Cell Stem Cell
, vol.10
, pp. 385-397
-
-
Mou, H.1
Zhao, R.2
Sherwood, R.3
-
58
-
-
84899644608
-
Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells
-
Firth AL, Dargitz CT, Qualls SJ et al (2014) Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells. Proc Natl Acad Sci U S A. doi:10.1073/pnas.1403470111
-
(2014)
Proc Natl Acad Sci U S A
-
-
Firth, A.L.1
Dargitz, C.T.2
Qualls, S.J.3
-
59
-
-
84892149549
-
Efficient generation of lung and airway epithelial cells from human pluripotent stem cells
-
Huang SXL, Islam MN, O'Neill J et al (2013) Efficient generation of lung and airway epithelial cells from human pluripotent stem cells. Nat Biotechnol. doi:10.1038/nbt.2754
-
(2013)
Nat Biotechnol
-
-
Huang, S.X.L.1
Islam, M.N.2
O'Neill, J.3
-
60
-
-
84923821157
-
The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells
-
Huang SXL, Green MD, de Carvalho AT et al (2015) The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells. Nat Protoc 10:413–425. doi:10.1038/nprot.2015.023
-
(2015)
Nat Protoc
, vol.10
, pp. 413-425
-
-
Huang, S.X.L.1
Green, M.D.2
de Carvalho, A.T.3
-
61
-
-
84866067664
-
Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein
-
Wong AP, Bear CE, Chin S et al (2012) Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein. Nat Biotechnol 30:876–882. doi:10.1038/nbt.2328
-
(2012)
Nat Biotechnol
, vol.30
, pp. 876-882
-
-
Wong, A.P.1
Bear, C.E.2
Chin, S.3
-
62
-
-
84923790747
-
Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells
-
Wong AP, Chin S, Xia S et al (2015) Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells. Nat Protoc 10:363–381. doi:10.1038/nprot.2015.021
-
(2015)
Nat Protoc
, vol.10
, pp. 363-381
-
-
Wong, A.P.1
Chin, S.2
Xia, S.3
-
63
-
-
84886750797
-
Human iPS cell-derived alveolar epithelium repopulates lung extracellular matrix
-
Ghaedi M, Calle EA, Mendez JJ et al (2013) Human iPS cell-derived alveolar epithelium repopulates lung extracellular matrix. J Clin Invest 123:4950–4962. doi:10.1172/JCI68793
-
(2013)
J Clin Invest
, vol.123
, pp. 4950-4962
-
-
Ghaedi, M.1
Calle, E.A.2
Mendez, J.J.3
-
64
-
-
84919799219
-
Three-dimensional culture and FGF signaling drive differentiation of murine pluripotent cells to distal lung epithelial cells
-
Fox E, Shojaie S, Wang J et al (2015) Three-dimensional culture and FGF signaling drive differentiation of murine pluripotent cells to distal lung epithelial cells. Stem Cells Dev 24:21–35. doi:10.1089/scd.2014.0227
-
(2015)
Stem Cells Dev
, vol.24
, pp. 21-35
-
-
Fox, E.1
Shojaie, S.2
Wang, J.3
-
65
-
-
84900529199
-
Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq
-
Treutlein B, Brownfield DG, Wu AR et al (2014) Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq. Nature 509:371–375. doi:10.1038/nature13173
-
(2014)
Nature
, vol.509
, pp. 371-375
-
-
Treutlein, B.1
Brownfield, D.G.2
Wu, A.R.3
-
66
-
-
84918561297
-
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
-
McCracken KW, Catá EM, Crawford CM et al (2014) Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. Nature 516:400–404. doi:10.1038/nature13863
-
(2014)
Nature
, vol.516
, pp. 400-404
-
-
McCracken, K.W.1
Catá, E.M.2
Crawford, C.M.3
-
67
-
-
84964313624
-
An in vivo model of human small intestine using pluripotent stem cells
-
Watson CL, Mahe MM, Múnera J et al (2014) An in vivo model of human small intestine using pluripotent stem cells. Nat Med 20:1310–1314. doi:10.1038/nm.3737
-
(2014)
Nat Med
, vol.20
, pp. 1310-1314
-
-
Watson, C.L.1
Mahe, M.M.2
Múnera, J.3
-
68
-
-
85015264112
-
Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
-
Takasato M, Er PX, Chiu HS et al (2016) Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature 536:238–238. doi:10.1038/nature17982
-
(2016)
Nature
, vol.536
, pp. 238
-
-
Takasato, M.1
Er, P.X.2
Chiu, H.S.3
-
69
-
-
84960194392
-
Complex tissue and disease modeling using hiPSCs
-
Passier R, Orlova V, Mummery C (2016) Complex tissue and disease modeling using hiPSCs. Cell Stem Cell 18:309–321. doi:10.1016/j.stem.2016.02.011
-
(2016)
Cell Stem Cell
, vol.18
, pp. 309-321
-
-
Passier, R.1
Orlova, V.2
Mummery, C.3
-
70
-
-
84959287405
-
BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors
-
Tadokoro T, Gao X, Hong CC et al (2016) BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors. Development 143:764–773. doi:10.1242/dev.126656
-
(2016)
Development
, vol.143
, pp. 764-773
-
-
Tadokoro, T.1
Gao, X.2
Hong, C.C.3
-
71
-
-
84980343841
-
GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells
-
This publication elegantly applies gene editing technology to study differentiation of human airway basal cells grown as organoids
-
• Gao X, Bali AS, Randell SH, Hogan BLM (2015) GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells. J Cell Biol 211:669–682. doi:10.1083/jcb.201506014 This publication elegantly applies gene editing technology to study differentiation of human airway basal cells grown as organoids
-
(2015)
J Cell Biol
, vol.211
, pp. 669-682
-
-
Gao, X.1
Bali, A.S.2
Randell, S.H.3
Hogan, B.L.M.4
-
72
-
-
84907228030
-
IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells
-
Tadokoro T, Wang Y, Barak LS et al (2014) IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells. Proc Natl Acad Sci U S A 111:E3641–E3649. doi:10.1073/pnas.1409781111
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E3641-E3649
-
-
Tadokoro, T.1
Wang, Y.2
Barak, L.S.3
-
73
-
-
84887619426
-
Dedifferentiation of committed epithelial cells into stem cells in vivo
-
Tata PR, Mou H, Pardo-Saganta A et al (2013) Dedifferentiation of committed epithelial cells into stem cells in vivo. Nature 503:218–223. doi:10.1038/nature12777
-
(2013)
Nature
, vol.503
, pp. 218-223
-
-
Tata, P.R.1
Mou, H.2
Pardo-Saganta, A.3
-
74
-
-
0036891878
-
Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative population
-
You Y, Richer EJ, Huang T, Brody SL (2002) Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative population. Am J Physiol Lung Cell Mol Physiol 283:L1315–L1321. doi:10.1152/ajplung.00169.2002
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.283
, pp. L1315-L1321
-
-
You, Y.1
Richer, E.J.2
Huang, T.3
Brody, S.L.4
-
75
-
-
85072142592
-
Expansion of human airway basal stem cells and their differentiation as 3D tracheospheres
-
Hynds RE, Butler CR, Janes SM, Giangreco A (2016) Expansion of human airway basal stem cells and their differentiation as 3D tracheospheres. Methods Mol Biol. doi:10.1007/7651_2016_5
-
(2016)
Methods Mol Biol
-
-
Hynds, R.E.1
Butler, C.R.2
Janes, S.M.3
Giangreco, A.4
-
76
-
-
84990922590
-
Dual SMAD signaling inhibition enables long-term expansion of diverse epithelial basal cells
-
Mou H, Vinarsky V, Tata PR et al (2016) Dual SMAD signaling inhibition enables long-term expansion of diverse epithelial basal cells. Cell Stem Cell. doi:10.1016/j.stem.2016.05.012
-
(2016)
Cell Stem Cell
-
-
Mou, H.1
Vinarsky, V.2
Tata, P.R.3
-
77
-
-
80051576423
-
Functional analysis of two distinct bronchiolar progenitors during lung injury and repair
-
Teisanu RM, Chen H, Matsumoto K et al (2011) Functional analysis of two distinct bronchiolar progenitors during lung injury and repair. Am J Respir Cell Mol Biol 44:794–803. doi:10.1165/rcmb.2010-0098OC
-
(2011)
Am J Respir Cell Mol Biol
, vol.44
, pp. 794-803
-
-
Teisanu, R.M.1
Chen, H.2
Matsumoto, K.3
-
78
-
-
80155137529
-
Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization
-
Ding B-S, Nolan DJ, Guo P et al (2011) Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell 147:539–553. doi:10.1016/j.cell.2011.10.003
-
(2011)
Cell
, vol.147
, pp. 539-553
-
-
Ding, B.-S.1
Nolan, D.J.2
Guo, P.3
-
79
-
-
84923146107
-
Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration
-
Rafii S, Cao Z, Lis R et al (2015) Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration. Nat Cell Biol 17:123–136. doi:10.1038/ncb3096
-
(2015)
Nat Cell Biol
, vol.17
, pp. 123-136
-
-
Rafii, S.1
Cao, Z.2
Lis, R.3
-
80
-
-
84957431360
-
Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis
-
Cao Z, Lis R, Ginsberg M et al (2016) Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis. Nat Med 22:154–162. doi:10.1038/nm.4035
-
(2016)
Nat Med
, vol.22
, pp. 154-162
-
-
Cao, Z.1
Lis, R.2
Ginsberg, M.3
-
81
-
-
84928381028
-
Telomere dysfunction causes alveolar stem cell failure
-
Alder JK, Barkauskas CE, Limjunyawong N et al (2015) Telomere dysfunction causes alveolar stem cell failure. Proc Natl Acad Sci U S A 112:5099–5104. doi:10.1073/pnas.1504780112
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 5099-5104
-
-
Alder, J.K.1
Barkauskas, C.E.2
Limjunyawong, N.3
-
82
-
-
80155148257
-
Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection
-
Kumar PA, Hu Y, Yamamoto Y et al (2011) Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection. Cell 147:525–538. doi:10.1016/j.cell.2011.10.001
-
(2011)
Cell
, vol.147
, pp. 525-538
-
-
Kumar, P.A.1
Hu, Y.2
Yamamoto, Y.3
-
83
-
-
84923075311
-
Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury
-
Vaughan AE, Brumwell AN, Xi Y et al (2015) Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury. Nature 517:621–625. doi:10.1038/nature14112
-
(2015)
Nature
, vol.517
, pp. 621-625
-
-
Vaughan, A.E.1
Brumwell, A.N.2
Xi, Y.3
-
84
-
-
84923075310
-
p63+Krt5+ distal airway stem cells are essential for lung regeneration
-
Zuo W, Zhang T, Wu DZ et al (2014) p63+Krt5+ distal airway stem cells are essential for lung regeneration. Nature 517:616–620. doi:10.1038/nature13903
-
(2014)
Nature
, vol.517
, pp. 616-620
-
-
Zuo, W.1
Zhang, T.2
Wu, D.Z.3
-
85
-
-
84994641774
-
Rare SOX2(+) airway progenitor cells generate KRT5(+) cells that repopulate damaged alveolar parenchyma following influenza virus infection
-
Ray S, Chiba N, Yao C et al (2016) Rare SOX2(+) airway progenitor cells generate KRT5(+) cells that repopulate damaged alveolar parenchyma following influenza virus infection. Stem Cell Reports 7:817–825. doi:10.1016/j.stemcr.2016.09.010
-
(2016)
Stem Cell Reports
, vol.7
, pp. 817-825
-
-
Ray, S.1
Chiba, N.2
Yao, C.3
-
86
-
-
84870502577
-
Human nasal and tracheo-bronchial respiratory epithelial cell culture
-
Fulcher ML, Randell SH (2013) Human nasal and tracheo-bronchial respiratory epithelial cell culture. Methods Mol Biol 945:109–121. doi:10.1007/978-1-62703-125-7_8
-
(2013)
Methods Mol Biol
, vol.945
, pp. 109-121
-
-
Fulcher, M.L.1
Randell, S.H.2
-
87
-
-
85006202055
-
IL-1α mediates cellular cross-talk in the airway epithelial mesenchymal trophic unit
-
Hill AR, Donaldson JE, Blume C et al (2016) IL-1α mediates cellular cross-talk in the airway epithelial mesenchymal trophic unit. Tissue Barriers 4:e1206378. doi:10.1080/21688370.2016.1206378
-
(2016)
Tissue Barriers
, vol.4
-
-
Hill, A.R.1
Donaldson, J.E.2
Blume, C.3
-
88
-
-
84862892836
-
Airway basal cell vascular endothelial growth factor-mediated cross-talk regulates endothelial cell-dependent growth support of human airway basal cells
-
Curradi G, Walters MS, Ding B-S et al (2012) Airway basal cell vascular endothelial growth factor-mediated cross-talk regulates endothelial cell-dependent growth support of human airway basal cells. Cell Mol Life Sci 69:2217–2231. doi:10.1007/s00018-012-0922-8
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 2217-2231
-
-
Curradi, G.1
Walters, M.S.2
Ding, B.-S.3
-
89
-
-
84880292828
-
A functional CFTR assay using primary cystic fibrosis intestinal organoids
-
Dekkers JF, Wiegerinck CL, de Jonge HR et al (2013) A functional CFTR assay using primary cystic fibrosis intestinal organoids. Nat Med 19:939–945. doi:10.1038/nm.3201
-
(2013)
Nat Med
, vol.19
, pp. 939-945
-
-
Dekkers, J.F.1
Wiegerinck, C.L.2
de Jonge, H.R.3
-
90
-
-
84986332708
-
Replication of human noroviruses in stem cell-derived human enteroids
-
Ettayebi K, Crawford SE, Murakami K et al (2016) Replication of human noroviruses in stem cell-derived human enteroids. Science 353:1387–1393. doi:10.1126/science.aaf5211
-
(2016)
Science
, vol.353
, pp. 1387-1393
-
-
Ettayebi, K.1
Crawford, S.E.2
Murakami, K.3
-
91
-
-
85108819466
-
Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis
-
Xu Y, Mizuno T, Sridharan A et al (2016) Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis. JCI Insight 1:e90558. doi:10.1172/jci.insight.90558
-
(2016)
JCI Insight
, vol.1
-
-
Xu, Y.1
Mizuno, T.2
Sridharan, A.3
|