Generation of alveolar epithelial spheroids via isolated progenitor cells from human pluripotent stem cells

Stem Cell Reports

Volumn 3, Issue 3, 2014, Pages 394-403

  Gotoh, Shimpei ^a   Ito, Isao ^a,b   Nagasaki, Tadao ^a   Yamamoto, Yuki ^a   Konishi, Satoshi ^a   Korogi, Yohei ^a   Matsumoto, Hisako ^a   Muro, Shigeo ^a   Hirai, Toyohiro ^a   Funato, Michinori ^c   Mae, Shin Ichi ^c   Toyoda, Taro ^c   Sato Otsubo, Aiko ^a   Ogawa, Seishi ^a   Osafune, Kenji ^c   Mishima, Michiaki ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYPEPTIDASE; CARBOXYPEPTIDASE M; FIBROBLAST GROWTH FACTOR 10; HEPATOCYTE NUCLEAR FACTOR 3BETA; INHIBITOR OF DIFFERENTIATION 2; RETINOIC ACID; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 6; TRANSCRIPTION FACTOR NKX2.1; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SOX17; UNCLASSIFIED DRUG; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; METALLOPROTEINASE;

ANIMAL CELL; ARTICLE; CELL LINEAGE; CELL SELECTION; CHROMOSOME 16; CHROMOSOME 20; COCULTURE; ENDODERM; FETUS; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LAMELLAR BODY; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROBLAST; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPHEROID CELL; ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CELL SEPARATION; CYTOLOGY; EMBRYONIC STEM CELL; EPITHELIUM CELL; LUNG ALVEOLUS; MULTICELLULAR SPHEROID; PROCEDURES;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL SEPARATION; CELLS, CULTURED; COCULTURE TECHNIQUES; EMBRYONIC STEM CELLS; EPITHELIAL CELLS; GPI-LINKED PROTEINS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; METALLOENDOPEPTIDASES; MICE; PLURIPOTENT STEM CELLS; PULMONARY ALVEOLI; SPHEROIDS, CELLULAR;

EID: 84913587019     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2014.07.005     Document Type: Article

References (30)

1. C.E. Barkauskas, M.J. Cronce, C.R. Rackley, E.J. Bowie, D.R. Keene, B.R. Stripp, S.H. Randell, P.W. Noble, and B.L. Hogan Type 2 alveolar cells are stem cells in adult lung J. Clin. Invest. 123 2013 3025 3036
2. T.J. Desai, D.G. Brownfield, and M.A. Krasnow Alveolar progenitor and stem cells in lung development, renewal and cancer Nature 507 2014 190 194
3. L.G. Dobbs Isolation and culture of alveolar type II cells Am. J. Physiol. 258 1990 L134 L147
4. A.L. Firth, C.T. Dargitz, S.J. Qualls, T. Menon, R. Wright, O. Singer, F.H. Gage, A. Khanna, and I.M. Verma Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells Proc. Natl. Acad. Sci. USA 111 2014 E1723 E1730
5. M. Ghaedi, E.A. Calle, J.J. Mendez, A.L. Gard, J. Balestrini, A. Booth, P.F. Bove, L. Gui, E.S. White, and L.E. Niklason Human iPS cell-derived alveolar epithelium repopulates lung extracellular matrix J. Clin. Invest. 123 2013 4950 4962
6. L.W. Gonzales, S.H. Guttentag, K.C. Wade, A.D. Postle, and P.L. Ballard Differentiation of human pulmonary type II cells in vitro by glucocorticoid plus cAMP Am. J. Physiol. Lung Cell. Mol. Physiol. 283 2002 L940 L951
7. M.D. Green, A. Chen, M.C. Nostro, S.L. d'Souza, C. Schaniel, I.R. Lemischka, V. Gouon-Evans, G. Keller, and H.W. Snoeck Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells Nat. Biotechnol. 29 2011 267 272
8. K.S. Harris, Z. Zhang, M.T. McManus, B.D. Harfe, and X. Sun Dicer function is essential for lung epithelium morphogenesis Proc. Natl. Acad. Sci. USA 103 2006 2208 2213
9. S.X. Huang, M.N. Islam, J. O'Neill, Z. Hu, Y.G. Yang, Y.W. Chen, M. Mumau, M.D. Green, G. Vunjak-Novakovic, J. Bhattacharya, and H.W. Snoeck Efficient generation of lung and airway epithelial cells from human pluripotent stem cells Nat. Biotechnol. 32 2014 84 91
10. M. Kajiwara, T. Aoi, K. Okita, R. Takahashi, H. Inoue, N. Takayama, H. Endo, K. Eto, J. Toguchida, S. Uemoto, and S. Yamanaka Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells Proc. Natl. Acad. Sci. USA 109 2012 12538 12543
11. A. Khoor, M.T. Stahlman, M.E. Gray, and J.A. Whitsett Temporal-spatial distribution of SP-B and SP-C proteins and mRNAs in developing respiratory epithelium of human lung J. Histochem. Cytochem. 42 1994 1187 1199
12. C.F. Kim, E.L. Jackson, A.E. Woolfenden, S. Lawrence, I. Babar, S. Vogel, D. Crowley, R.T. Bronson, and T. Jacks Identification of bronchioalveolar stem cells in normal lung and lung cancer Cell 121 2005 823 835
13. S. Kimura, Y. Hara, T. Pineau, P. Fernandez-Salguero, C.H. Fox, J.M. Ward, and F.J. Gonzalez The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary Genes Dev. 10 1996 60 69
14. T.A. Longmire, L. Ikonomou, F. Hawkins, C. Christodoulou, Y. Cao, J.C. Jean, L.W. Kwok, H. Mou, J. Rajagopal, and S.S. Shen Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells Cell Stem Cell 10 2012 398 411
15. S. Mae, A. Shono, F. Shiota, T. Yasuno, M. Kajiwara, N. Gotoda-Nishimura, S. Arai, A. Sato-Otubo, T. Toyoda, and K. Takahashi Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells Nat. Commun. 4 2013 1367
16. J.L. McQualter, K. Yuen, B. Williams, and I. Bertoncello Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung Proc. Natl. Acad. Sci. USA 107 2010 1414 1419
17. H. Mou, R. Zhao, R.I. Sherwood, T. Ahfeldt, A. Lapey, L. Sicillian, K.I. Izvolsky, K. Musunuru, C. Cowan, and J. Rajagopal Generation of multipotent embryonic lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs Cell Stem Cell 10 2012 385 397
18. A. Nagae, M. Abe, R.P. Becker, P.A. Deddish, R.A. Skidgel, and E.G. Erdös High concentration of carboxypeptidase M in lungs: presence of the enzyme in alveolar type I cells Am. J. Respir. Cell Mol. Biol. 9 1993 221 229
19. M. Nakagawa, M. Koyanagi, K. Tanabe, K. Takahashi, T. Ichisaka, T. Aoi, K. Okita, Y. Mochiduki, N. Takizawa, and S. Yamanaka Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts Nat. Biotechnol. 26 2008 101 106
20. K. Okita, T. Yamakawa, Y. Matsumura, Y. Sato, N. Amano, A. Watanabe, N. Goshima, and S. Yamanaka An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells Stem Cells 31 2013 458 466
21. E.L. Rawlins, C.P. Clark, Y. Xue, and B.L. Hogan The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells Development 136 2009 3741 3745
22. E.L. Rawlins, T. Okubo, Y. Xue, D.M. Brass, R.L. Auten, H. Hasegawa, F. Wang, and B.L. Hogan The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium Cell Stem Cell 4 2009 525 534
23. J.R. Rock, and B.L. Hogan Epithelial progenitor cells in lung development, maintenance, repair, and disease Annu. Rev. Cell Dev. Biol. 27 2011 493 512
24. J.R. Rock, M.W. Onaitis, E.L. Rawlins, Y. Lu, C.P. Clark, Y. Xue, S.H. Randell, and B.L. Hogan Basal cells as stem cells of the mouse trachea and human airway epithelium Proc. Natl. Acad. Sci. USA 106 2009 12771 12775
25. K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, K. Tomoda, and S. Yamanaka Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 2007 861 872
26. O.J. Tamplin, D. Kinzel, B.J. Cox, C.E. Bell, J. Rossant, and H. Lickert Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives BMC Genomics 9 2008 511
27. J.A. Thomson, J. Itskovitz-Eldor, S.S. Shapiro, M.A. Waknitz, J.J. Swiergiel, V.S. Marshall, and J.M. Jones Embryonic stem cell lines derived from human blastocysts Science 282 1998 1145 1147
28. J.A. Whitsett, S.E. Wert, and T.E. Weaver Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease Annu. Rev. Med. 61 2010 105 119
29. A.P. Wong, C.E. Bear, S. Chin, P. Pasceri, T.O. Thompson, L.J. Huan, F. Ratjen, J. Ellis, and J. Rossant Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein Nat. Biotechnol. 30 2012 876 882
30. W. Yu, X. Fang, A. Ewald, K. Wong, C.A. Hunt, Z. Werb, M.A. Matthay, and K. Mostov Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis Mol. Biol. Cell 18 2007 1693 1700