Telomere dysfunction causes alveolar stem cell failure

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 16, 2015, Pages 5099-5104

  Aldera, Jonathan K ^a,b,f   Barkauskas, Christina E ^c   Limjunyawong, Nathachit ^d   Stanley, Susan E ^a,b   Kembou, Frant ^a,b   Tuder, Rubin M ^e   Hogan, Brigid L M ^c   Mitzner, Wayne ^d   Armanios, Mary ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^f BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

Emphysema; Idiopathic pulmonary fibrosis; Senescence; Telomerase

Indexed keywords

BLEOMYCIN; PROTEIN P53; TELOMERIC REPEAT BINDING FACTOR 2; PEPTIDE; SFTPC PROTEIN, MOUSE; TRF2 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; IMMUNE RESPONSE; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM CELL; LUNG DEVELOPMENT; LUNG DISEASE; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; SENESCENCE; STEM CELL; STROMA CELL; TELOMERE SHORTENING; UPREGULATION; AGING; ANIMAL; CELL PROLIFERATION; EPITHELIUM CELL; GENE DELETION; IMMUNITY; IMMUNOLOGY; LUNG ALVEOLUS; MESODERM; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; SIGNAL TRANSDUCTION; TELOMERE;

MUS;

AGING; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; EPITHELIAL CELLS; GENE DELETION; IMMUNITY; INFLAMMATION; MESODERM; MICE; PARACRINE COMMUNICATION; PEPTIDES; PULMONARY ALVEOLI; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR; STEM CELLS; STROMAL CELLS; TELOMERE; TELOMERE SHORTENING; TELOMERIC REPEAT BINDING PROTEIN 2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84928381028     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1504780112     Document Type: Article

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