A three-dimensional human model of the fibroblast activation that accompanies bronchopulmonary dysplasia identifies Notch-mediated pathophysiology

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 310, Issue 10, 2016, Pages L889-L898

  Sucre, Jennifer M S ^a   Wilkinson, Dan ^b   Vijayaraj, Preethi ^a,c   Paul, Manash ^a   Dunn, Bruce ^b   Alva Ornelas, Jackelyn A ^a   Gomperts, Brigitte N ^a,b,c  

^a MATTEL CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Development; Disease modeling; Fibrosis; Lung prematurity; Signaling pathways

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; JAGGED1; NOTCH RECEPTOR; NOTCH1 RECEPTOR; ALGINIC ACID; CULTURE MEDIUM; GLUCURONIC ACID; HEXURONIC ACID;

ARTICLE; AUTOPSY; CELL ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; FETUS LUNG; HUMAN; HUMAN CELL; INFANT; LUNG DYSPLASIA; LUNG FIBROBLAST; LUNG PARENCHYMA; MITOSIS RATE; MULTIGENE FAMILY; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; THREE DIMENSIONAL IMAGING; UPREGULATION; CELL CULTURE; CELL CULTURE TECHNIQUE; CELL HYPOXIA; CHEMISTRY; CULTURE MEDIUM; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ALGINATES; BRONCHOPULMONARY DYSPLASIA; CELL CULTURE TECHNIQUES; CELL HYPOXIA; CELLS, CULTURED; CULTURE MEDIA; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84984640140     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00446.2015     Document Type: Article

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