Empagliflozin, SGLT2 inhibitor, attenuates renal fibrosis in rats exposed to unilateral ureteric obstruction: potential role of klotho expression

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 391, Issue 12, 2018, Pages 1347-1360

  Abbas, Noha A T ^a   Salem, Amal El ^a   Awad, Mohammed M ^a  

^a ZAGAZIG UNIVERSITY   (Egypt)

Author keywords

Connective tissue growth factor; Empagliflozin; Klotho; Nuclear factor B; Renoprotective

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CONNECTIVE TISSUE GROWTH FACTOR; CREATININE; DISTILLED WATER; EMPAGLIFLOZIN; FIBRONECTIN; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KLOTHO PROTEIN; SODIUM; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1; UREA; WNT1 PROTEIN; BENZHYDRYL DERIVATIVE; BETA GLUCURONIDASE; GLUCOSIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT CHANGE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; IN VIVO STUDY; KIDNEY DYSFUNCTION; KIDNEY FIBROSIS; KIDNEY HOMOGENATE; LABORATORY TEST; MALE; MEASUREMENT; NONHUMAN; PROPHYLAXIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; RENAL PROTECTION; SODIUM BLOOD LEVEL; UREA BLOOD LEVEL; URETER OBSTRUCTION; ANIMAL; DRUG EFFECT; FIBROSIS; KIDNEY; KIDNEY DISEASE; METABOLISM; PATHOLOGY; PHARMACOLOGY; WISTAR RAT;

ANIMALS; BENZHYDRYL COMPOUNDS; FIBROSIS; GLUCOSIDES; GLUCURONIDASE; KIDNEY; KIDNEY DISEASES; MALE; RATS, WISTAR; SODIUM-GLUCOSE TRANSPORTER 2 INHIBITORS; URETERAL OBSTRUCTION;

EID: 85051482435     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-018-1544-y     Document Type: Article

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