The sodium-glucose co-transporter 2 inhibitor, empagliflozin, protects against diabetic cardiomyopathy by inhibition of the endoplasmic reticulum stress pathway

Cellular Physiology and Biochemistry

Volumn 41, Issue 6, 2017, Pages 2503-2512

  Zhou, Yang ^a   Wu, Wei ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Diabetic cardiomyopathy; Empagliflozin; Endoplasmic reticulum stress

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; BINDING PROTEIN; CASPASE 12; EMPAGLIFLOZIN; ENHANCER BINDING PROTEIN HOMOLOGOUS PROTEIN; EOSIN; GLUCOSE REGULATED PROTEIN 78; HEMATOXYLIN; MESSENGER RNA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; BENZHYDRYL DERIVATIVE; GLUCOSE BLOOD LEVEL; GLUCOSIDE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; PROTECTIVE AGENT; SODIUM GLUCOSE COTRANSPORTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIAC MUSCLE CELL; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DOWN REGULATION; DRUG MEGADOSE; ENDOPLASMIC RETICULUM STRESS; GLUCOSE BLOOD LEVEL; HEART FUNCTION; HEART LEFT VENTRICLE FUNCTION; HEART PROTECTION; HEMODYNAMICS; HISTOPATHOLOGY; LOW DRUG DOSE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANALYSIS; ANIMAL; ANTAGONISTS AND INHIBITORS; CARDIAC MUSCLE; CHEMICALLY INDUCED; CYTOLOGY; DIABETIC CARDIOMYOPATHIES; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; GENETICS; METABOLISM; PATHOLOGY; WISTAR RAT;

ANIMALS; APOPTOSIS; BENZHYDRYL COMPOUNDS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; DOWN-REGULATION; ENDOPLASMIC RETICULUM STRESS; GLUCOSIDES; HEAT-SHOCK PROTEINS; HEMODYNAMICS; MALE; MYOCARDIUM; MYOCYTES, CARDIAC; PROTECTIVE AGENTS; RATS; RATS, WISTAR; SODIUM-GLUCOSE TRANSPORT PROTEINS; TNF RECEPTOR-ASSOCIATED FACTOR 2; TRANSCRIPTION FACTOR CHOP;

EID: 85021278361     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000475942     Document Type: Article

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