Decreased renal α-Klotho expression in early diabetic nephropathy in humans and mice and its possible role in urinary calcium excretion

Kidney International

Volumn 81, Issue 6, 2012, Pages 539-547

  Asai, Osamu ^a   Nakatani, Kimihiko ^a   Tanaka, Tomohiro ^b   Sakan, Hirokazu ^a   Imura, Akihiro ^b   Yoshimoto, Shuhei ^a   Samejima, Ken Ichi ^a   Yamaguchi, Yukinari ^a   Matsui, Masaru ^a   Akai, Yasuhiro ^a   Konishi, Noboru ^a   Iwano, Masayuki ^a,c   Nabeshima, Yoichi ^b   Saito, Yoshihiko ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF FUKUI   (Japan)

Author keywords

diabetic nephropathy; hypercalciuria; hypoxia

Indexed keywords

ALPHA KLOTHO PROTEIN; CALCIUM; KLOTHO PROTEIN; MESSENGER RNA; STREPTOZOCIN; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM EXCRETION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETIC NEPHROPATHY; ENZYME ACTIVITY; GLOMERULUS FILTRATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERCALCIURIA; IMMUNOGLOBULIN A NEPHROPATHY; MOUSE; MULTIPLE REGRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

EID: 84857784178     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2011.423     Document Type: Article

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