In vivo pancreatic β-cell-specific expression of antiaging gene klotho: A novel approach for preserving β-cells in type 2 diabetes

Diabetes

Volumn 64, Issue 4, 2015, Pages 1444-1458

  Lin, Yi ^a   Sun, Zhongjie ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CYCLINE; INSULIN; KLOTHO PROTEIN; LC3 PROTEIN; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG; BETA GLUCURONIDASE;

ADULT; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BODY WEIGHT; CELLULAR DISTRIBUTION; CYTOSOL; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; FLUID INTAKE; FOOD INTAKE; GENE EXPRESSION; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN SENSITIVITY; INSULINOMA; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; URINE VOLUME; WESTERN BLOTTING; ANIMAL; MALE; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; DIABETES MELLITUS, TYPE 2; GLUCURONIDASE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; OXIDATIVE STRESS; SUPEROXIDES;

EID: 84962004021     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0632     Document Type: Article

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