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Volumn 27, Issue 56, 2008, Pages 7094-7105

Klotho: A tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer

Author keywords

Breast cancer; Insulin; Insulin growth factor 1; Klotho; Tumor suppressor

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; FIBROBLAST GROWTH FACTOR; KI 67 ANTIGEN; KLOTHO PROTEIN; PROTEIN P53; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

EID: 58149229326     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.292     Document Type: Article
Times cited : (266)

References (41)
  • 3
    • 0035884617 scopus 로고    scopus 로고
    • Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells
    • Bartucci M, Morelli C, Mauro L, Ando S, Surmacz E. (2001). Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells. Cancer Res 61: 6747-6754.
    • (2001) Cancer Res , vol.61 , pp. 6747-6754
    • Bartucci, M.1    Morelli, C.2    Mauro, L.3    Ando, S.4    Surmacz, E.5
  • 4
    • 47749148805 scopus 로고    scopus 로고
    • Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1
    • Cha S-K, Ortega B, Kurosu H, Rosenblatt KP, Kuro-o M, Huang C-L. (2008). Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1. Proc Natl Acad Sci 105: 9805-9810.
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 9805-9810
    • Cha, S.-K.1    Ortega, B.2    Kurosu, H.3    Rosenblatt, K.P.4    Kuro-o, M.5    Huang, C.-L.6
  • 6
    • 38049144010 scopus 로고    scopus 로고
    • Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17
    • Chen C-D, Podvin S, Gillespie E, Leeman SE, Abraham CR. (2007). Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17. Proc Natl Acad Sci 104: 19796-19801.
    • (2007) Proc Natl Acad Sci , vol.104 , pp. 19796-19801
    • Chen, C.-D.1    Podvin, S.2    Gillespie, E.3    Leeman, S.E.4    Abraham, C.R.5
  • 8
    • 33749342012 scopus 로고    scopus 로고
    • Klotho RNAi induces premature senescence of human cells via a p53/p21 dependent pathway
    • de Oliveira RM. (2006). Klotho RNAi induces premature senescence of human cells via a p53/p21 dependent pathway. FEBS Letters 580: 5753-5758.
    • (2006) FEBS Letters , vol.580 , pp. 5753-5758
    • de Oliveira, R.M.1
  • 9
    • 0037974416 scopus 로고    scopus 로고
    • The epithelial calcium channels, TRPV5 & TRPV6: From identification towards regulation
    • den Dekker E, Hoenderop JGJ, Nilius B, Bindels RJM. (2003). The epithelial calcium channels, TRPV5 & TRPV6: from identification towards regulation. Cell Calcium 33: 497-507.
    • (2003) Cell Calcium , vol.33 , pp. 497-507
    • den Dekker, E.1    Hoenderop, J.G.J.2    Nilius, B.3    Bindels, R.J.M.4
  • 10
    • 0036632316 scopus 로고    scopus 로고
    • Basic fibroblast growth factor mediated growth inhibition in breast cancer cells is independent of ras signaling pathway
    • Fenig E, Szyper-Kravitz M, Yerushalmi R, Lahav M, Beery E, Wasserman L et al. (2002). Basic fibroblast growth factor mediated growth inhibition in breast cancer cells is independent of ras signaling pathway. Oncol Rep 9: 875-877.
    • (2002) Oncol Rep , vol.9 , pp. 875-877
    • Fenig, E.1    Szyper-Kravitz, M.2    Yerushalmi, R.3    Lahav, M.4    Beery, E.5    Wasserman, L.6
  • 11
    • 0031041971 scopus 로고    scopus 로고
    • Basic fibroblast growth factor confers growth inhibition and mitogen-activated protein kinase activation in human breast cancer cells
    • Fenig E, Wieder R, Paglin S, Wang H, Persaud R, Haimovitz-Friedman A et al. (1997). Basic fibroblast growth factor confers growth inhibition and mitogen-activated protein kinase activation in human breast cancer cells. Clin Cancer Res 3: 135-142.
    • (1997) Clin Cancer Res , vol.3 , pp. 135-142
    • Fenig, E.1    Wieder, R.2    Paglin, S.3    Wang, H.4    Persaud, R.5    Haimovitz-Friedman, A.6
  • 12
    • 0029134568 scopus 로고
    • Insulin-like growth factor-1 inhibits cell death induced by anticancer drugs in the MCF-7 cells: Involvement of growth factors in drug resistance
    • Geier A, Beery R, Haimsohn M, Karasik A. (1995). Insulin-like growth factor-1 inhibits cell death induced by anticancer drugs in the MCF-7 cells: involvement of growth factors in drug resistance. Cancer Invest 13: 480-486.
    • (1995) Cancer Invest , vol.13 , pp. 480-486
    • Geier, A.1    Beery, R.2    Haimsohn, M.3    Karasik, A.4
  • 13
  • 14
    • 33748208668 scopus 로고    scopus 로고
    • C/EBP[beta] at the core of the TGF[beta] cytostatic response and its evasion in metastatic breast cancer cells
    • Gomis RR, Alarcon C, Nadal C, Van Poznak C, Massague J. (2006). C/EBP[beta] at the core of the TGF[beta] cytostatic response and its evasion in metastatic breast cancer cells. Cancer Cell 10: 203-214.
    • (2006) Cancer Cell , vol.10 , pp. 203-214
    • Gomis, R.R.1    Alarcon, C.2    Nadal, C.3    Van Poznak, C.4    Massague, J.5
  • 15
    • 0036171227 scopus 로고    scopus 로고
    • Aurintricarboxylic acid induces a distinct activation of the IGF-I receptor signaling within MDA-231 cells
    • Haimsohn M, Beery R, Karasik A, Kanety H, Geier A. (2002). Aurintricarboxylic acid induces a distinct activation of the IGF-I receptor signaling within MDA-231 cells. Endocrinology 143: 837-845.
    • (2002) Endocrinology , vol.143 , pp. 837-845
    • Haimsohn, M.1    Beery, R.2    Karasik, A.3    Kanety, H.4    Geier, A.5
  • 16
    • 31544464616 scopus 로고    scopus 로고
    • In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417
    • Haluska P, Carboni JM, Loegering DA, Lee FY, Wittman M, Saulnier MG et al. (2006). In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417. Cancer Res 66: 362-371.
    • (2006) Cancer Res , vol.66 , pp. 362-371
    • Haluska, P.1    Carboni, J.M.2    Loegering, D.A.3    Lee, F.Y.4    Wittman, M.5    Saulnier, M.G.6
  • 17
    • 0036632287 scopus 로고    scopus 로고
    • High basic fibroblast growth factor levels in nipple aspirate fluid are correlated with breast cancer
    • Hsiung R, Zhu W, Klein G, Qin W, Rosenberg A, Park P et al. (2002). High basic fibroblast growth factor levels in nipple aspirate fluid are correlated with breast cancer. Cancer J 8: 303-310.
    • (2002) Cancer J , vol.8 , pp. 303-310
    • Hsiung, R.1    Zhu, W.2    Klein, G.3    Qin, W.4    Rosenberg, A.5    Park, P.6
  • 19
    • 2342610541 scopus 로고    scopus 로고
    • Secreted Klotho protein in sera and CSF: Implication for post-translational cleavage in release of Klotho protein from cell membrane
    • Imura A, Iwano A, Tohyama O, Tsuji Y, Nozaki K, Hashimoto N et al. (2004). Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane. FEBS Lett 565: 143-147.
    • (2004) FEBS Lett , vol.565 , pp. 143-147
    • Imura, A.1    Iwano, A.2    Tohyama, O.3    Tsuji, Y.4    Nozaki, K.5    Hashimoto, N.6
  • 20
  • 21
    • 0034333526 scopus 로고    scopus 로고
    • Molecular cloning and expression analyses of mouse [beta]klotho, which encodes a novel Klotho family protein
    • Ito S, Kinoshita S, Shiraishi N, Nakagawa S, Sekine S, Fujimori T et al. (2000). Molecular cloning and expression analyses of mouse [beta]klotho, which encodes a novel Klotho family protein. Mech Dev 98: 115-119.
    • (2000) Mech Dev , vol.98 , pp. 115-119
    • Ito, S.1    Kinoshita, S.2    Shiraishi, N.3    Nakagawa, S.4    Sekine, S.5    Fujimori, T.6
  • 22
    • 0034685014 scopus 로고    scopus 로고
    • Establishment of the anti-klotho monoclonal antibodies and detection of klotho protein in kidneys
    • Kato Y, Arakawa E, Kinoshita S, Shirai A, Furuya A, Yamano K et al. (2000). Establishment of the anti-klotho monoclonal antibodies and detection of klotho protein in kidneys. Biochem Biophys Res Commun 267: 597-602.
    • (2000) Biochem Biophys Res Commun , vol.267 , pp. 597-602
    • Kato, Y.1    Arakawa, E.2    Kinoshita, S.3    Shirai, A.4    Furuya, A.5    Yamano, K.6
  • 23
    • 33748741795 scopus 로고    scopus 로고
    • Klotho is a genetic risk factor for ischemic stroke caused by cardioembolism in Korean females
    • Kim Y, Kim J-H, Nam YJ, Kong M, Kim YJ, Yu K-H et al. (2006). Klotho is a genetic risk factor for ischemic stroke caused by cardioembolism in Korean females. Neurosci Lett 407: 189-194.
    • (2006) Neurosci Lett , vol.407 , pp. 189-194
    • Kim, Y.1    Kim, J.-H.2    Nam, Y.J.3    Kong, M.4    Kim, Y.J.5    Yu, K.-H.6
  • 24
    • 0033965233 scopus 로고    scopus 로고
    • Basic fibroblast growth factor confers a less malignant phenotype in MDA-MB-231 human breast cancer cells
    • Korah RM, Sysounthone V, Golowa Y, Wieder R. (2000). Basic fibroblast growth factor confers a less malignant phenotype in MDA-MB-231 human breast cancer cells. Cancer Res 60: 733-740.
    • (2000) Cancer Res , vol.60 , pp. 733-740
    • Korah, R.M.1    Sysounthone, V.2    Golowa, Y.3    Wieder, R.4
  • 25
    • 0030724491 scopus 로고    scopus 로고
    • Mutation of the mouse klotho gene leads to a syndrome resembling ageing
    • Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T et al. (1997). Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 390: 45-51.
    • (1997) Nature , vol.390 , pp. 45-51
    • Kuro-o, M.1    Matsumura, Y.2    Aizawa, H.3    Kawaguchi, H.4    Suga, T.5    Utsugi, T.6
  • 28
    • 1342326910 scopus 로고    scopus 로고
    • Relevance of breast cancer cell lines as models for breast tumours: An update
    • Lacroix M, Leclercq G. (2004). Relevance of breast cancer cell lines as models for breast tumours: an update. Breast Cancer Res Treatment 83: 249-289.
    • (2004) Breast Cancer Res Treatment , vol.83 , pp. 249-289
    • Lacroix, M.1    Leclercq, G.2
  • 29
    • 34547491691 scopus 로고    scopus 로고
    • Role of cdk2 in the sequential phosphorylation/activation of C/EBPbeta during adipocyte differentiation
    • Li X, Kim JW, Gronborg M, Urlaub H, Lane MD, Tang Q-Q. (2007). Role of cdk2 in the sequential phosphorylation/activation of C/EBPbeta during adipocyte differentiation. Proc Natl Acad Sci 104: 11597-11602.
    • (2007) Proc Natl Acad Sci , vol.104 , pp. 11597-11602
    • Li, X.1    Kim, J.W.2    Gronborg, M.3    Urlaub, H.4    Lane, M.D.5    Tang, Q.-Q.6
  • 30
    • 0032567647 scopus 로고    scopus 로고
    • Identification of the human Klotho gene and its two transcripts encoding membrane and secreted Klotho protein
    • Matsumura Y, Aizawa H, Shiraki-Iida T, Nagai R, Kuro-o M, Nabeshima Y. (1998). Identification of the human Klotho gene and its two transcripts encoding membrane and secreted Klotho protein. Biochem Biophys Res Commun 242: 626-630.
    • (1998) Biochem Biophys Res Commun , vol.242 , pp. 626-630
    • Matsumura, Y.1    Aizawa, H.2    Shiraki-Iida, T.3    Nagai, R.4    Kuro-o, M.5    Nabeshima, Y.6
  • 31
    • 12144290914 scopus 로고    scopus 로고
    • Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors
    • Mitsiades CS, Mitsiades NS, McMullan CJ, Poulaki V, Shringarpure R, Akiyama M et al. (2004). Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors. Cancer Cell 5: 221-230.
    • (2004) Cancer Cell , vol.5 , pp. 221-230
    • Mitsiades, C.S.1    Mitsiades, N.S.2    McMullan, C.J.3    Poulaki, V.4    Shringarpure, R.5    Akiyama, M.6
  • 32
    • 0032578906 scopus 로고    scopus 로고
    • Molecular cloning of rat klotho cDNA: Markedly decreased expression of klotho by acute inflammatory stress
    • Ohyama Y, Kurabayashi M, Masuda H, Nakamura T, Aihara Y, Kaname T et al. (1998). Molecular cloning of rat klotho cDNA: markedly decreased expression of klotho by acute inflammatory stress. Biochem Biophys Res Commun 251: 920-925.
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 920-925
    • Ohyama, Y.1    Kurabayashi, M.2    Masuda, H.3    Nakamura, T.4    Aihara, Y.5    Kaname, T.6
  • 33
    • 0032489424 scopus 로고    scopus 로고
    • Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein
    • Shiraki-Iida T, Aizawa H, Matsumura Y, Sekine S, Iida A, Anazawa H et al. (1998). Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein. FEBS Lett 424: 6-10.
    • (1998) FEBS Lett , vol.424 , pp. 6-10
    • Shiraki-Iida, T.1    Aizawa, H.2    Matsumura, Y.3    Sekine, S.4    Iida, A.5    Anazawa, H.6
  • 34
    • 33845631059 scopus 로고    scopus 로고
    • Klotho converts canonical FGF receptor into a specific receptor for FGF23
    • Urakawa I, Yamazaki Y, Shimada T, Iijima K, Hasegawa H, Okawa K et al. (2006). Klotho converts canonical FGF receptor into a specific receptor for FGF23. Science 444: 770-774.
    • (2006) Science , vol.444 , pp. 770-774
    • Urakawa, I.1    Yamazaki, Y.2    Shimada, T.3    Iijima, K.4    Hasegawa, H.5    Okawa, K.6
  • 35
    • 0033812019 scopus 로고    scopus 로고
    • Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging
    • Utsugi T, Ohno T, Ohyama Y, Uchiyama T, Saito Y, Matsumura Y et al. (2000). Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging. Metabolism 49: 1118-1123.
    • (2000) Metabolism , vol.49 , pp. 1118-1123
    • Utsugi, T.1    Ohno, T.2    Ohyama, Y.3    Uchiyama, T.4    Saito, Y.5    Matsumura, Y.6
  • 36
    • 22744458796 scopus 로고    scopus 로고
    • The antiapoptotic effect of fibroblast growth factor-2 is mediated through nuclear factor-[kappa]B activation induced via interaction between Akt and I[kappa]B kinase-[beta] in breast cancer cells
    • Vandermoere F, El Yazidi-Belkoura I, Adriaenssens E, Lemoine J, Hondermarck H. (2005). The antiapoptotic effect of fibroblast growth factor-2 is mediated through nuclear factor-[kappa]B activation induced via interaction between Akt and I[kappa]B kinase-[beta] in breast cancer cells. Oncogene 24: 5482-5491.
    • (2005) Oncogene , vol.24 , pp. 5482-5491
    • Vandermoere, F.1    El Yazidi-Belkoura, I.2    Adriaenssens, E.3    Lemoine, J.4    Hondermarck, H.5
  • 38
    • 33747873279 scopus 로고    scopus 로고
    • 15-Hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer
    • Wolf I, O'Kelly J, Rubinek T, Tong M, Nguyen A, Lin BT et al. (2006a). 15-Hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer. Cancer Res 66: 7818-7823.
    • (2006) Cancer Res , vol.66 , pp. 7818-7823
    • Wolf, I.1    O'Kelly, J.2    Rubinek, T.3    Tong, M.4    Nguyen, A.5    Lin, B.T.6
  • 39
    • 33646433412 scopus 로고    scopus 로고
    • Association between diabetes mellitus and adverse characteristics of breast cancer at presentation
    • Wolf I, Sadetzki S, Gluck I, Oberman B, Ben-David M, Papa MZ et al. (2006b). Association between diabetes mellitus and adverse characteristics of breast cancer at presentation. Eur J Cancer 42: 1077-1082.
    • (2006) Eur J Cancer , vol.42 , pp. 1077-1082
    • Wolf, I.1    Sadetzki, S.2    Gluck, I.3    Oberman, B.4    Ben-David, M.5    Papa, M.Z.6
  • 40
    • 33344467985 scopus 로고    scopus 로고
    • Targeting insulin-like growth factor pathways
    • Yee D. (2006). Targeting insulin-like growth factor pathways. Br J Cancer 94: 465-468.
    • (2006) Br J Cancer , vol.94 , pp. 465-468
    • Yee, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.