Thymoquinone attenuates myocardial ischemia/reperfusion injury through activation of SIRT1 signaling

Cellular Physiology and Biochemistry

Volumn 47, Issue 3, 2018, Pages 1193-1206

  Lu, Yunyang ^a   Feng, Yingda ^a,b   Liu, Dan ^c   Zhang, Zhiran ^c   Gao, Kai ^b   Zhang, Wei ^b   Tang, Haifeng ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c The 210th Hospital of PLA   (China)

Author keywords

Ac p53; Apoptosis; Mitochondrial oxidative stress; Myocardial ischemia reperfusion injury; SIRT1; Thymoquinone

Indexed keywords

HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; MALONALDEHYDE; PROTEIN P53; SIRTINOL; SIRTUIN 1; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE; THYMOQUINONE; BENZOQUINONE DERIVATIVE; MUSCLE PROTEIN; SIRT1 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME SYNTHESIS; HEART INFARCTION SIZE; HEART LEFT VENTRICLE FUNCTION; HEART PROTECTION; MALE; MITOCHONDRION; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ACETYLATION; RAT; SIGNAL TRANSDUCTION; ANIMAL; CARDIAC MUSCLE; DRUG EFFECT; METABOLISM; PATHOLOGY; REPERFUSION INJURY; SPRAGUE DAWLEY RAT;

ANIMALS; BENZOQUINONES; MALE; MUSCLE PROTEINS; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SIGNAL TRANSDUCTION; SIRTUIN 1;

EID: 85048853090     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000490216     Document Type: Article

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