메뉴 건너뛰기




Volumn 390, Issue 1, 2017, Pages 69-76

Thymoquinone mitigate ischemia-reperfusion-induced liver injury in rats: a pivotal role of nitric oxide signaling pathway

Author keywords

eNOS; Hepatic ischemia reperfusion; iNOS; NOSTRIN; Thymoquinone

Indexed keywords

ACETYLCYSTEINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; MYELOPEROXIDASE; NITRIC OXIDE; NOSTRIN PROTEIN; PROTEIN; THYMOQUINONE; UNCLASSIFIED DRUG; ANTIOXIDANT; BENZOQUINONE DERIVATIVE; BIOLOGICAL MARKER; NOS2 PROTEIN, RAT; NOS3 PROTEIN, RAT; PEROXIDASE;

EID: 84990990438     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-016-1306-7     Document Type: Article
Times cited : (34)

References (35)
  • 1
    • 85007342508 scopus 로고    scopus 로고
    • Quercetin modulates iNOS, eNOS and NOSTRIN expressions and attenuates oxidative stress in warm hepatic ischemia-reperfusion injury in rats Beni-Suef University
    • Abd-Elbaset M, Arafa E-SA, El Sherbiny GA, Abdel-Bakky MS, Elgendy ANA (2015) Quercetin modulates iNOS, eNOS and NOSTRIN expressions and attenuates oxidative stress in warm hepatic ischemia-reperfusion injury in rats Beni-Suef University. Journal of Basic and Applied Sciences 4:246–255
    • (2015) Journal of Basic and Applied Sciences , vol.4 , pp. 246-255
    • Abd-Elbaset, M.1    Arafa, E.-S.A.2    El Sherbiny, G.A.3    Abdel-Bakky, M.S.4    Elgendy, A.N.A.5
  • 2
    • 33746190607 scopus 로고    scopus 로고
    • Neuroprotective effects of thymoquinone against transient forebrain ischemia in the rat hippocampus
    • COI: 1:CAS:528:DC%2BD28XntlWls7s%3D, PID: 16828080
    • Al-Majed AA, Al-Omar FA, Nagi MN (2006) Neuroprotective effects of thymoquinone against transient forebrain ischemia in the rat hippocampus. Eur J Pharmacol 543:40–47
    • (2006) Eur J Pharmacol , vol.543 , pp. 40-47
    • Al-Majed, A.A.1    Al-Omar, F.A.2    Nagi, M.N.3
  • 3
    • 23144457741 scopus 로고    scopus 로고
    • Protective effect of resveratrol against oxidative stress in cholestasis
    • COI: 1:CAS:528:DC%2BD2MXntVGmtLY%3D, PID: 16083749
    • Ara C et al (2005) Protective effect of resveratrol against oxidative stress in cholestasis. J Surg Res 127:112–117. doi:10.1016/j.jss.2005.01.024
    • (2005) J Surg Res , vol.127 , pp. 112-117
    • Ara, C.1
  • 6
    • 73649194769 scopus 로고
    • Improved method for the determination of blood glutathione
    • Beutler E, Duron O, Kelly B (1963) Improved method for the determination of blood glutathione. J Lab Clin Med 61:882–888
    • (1963) J Lab Clin Med , vol.61 , pp. 882-888
    • Beutler, E.1    Duron, O.2    Kelly, B.3
  • 7
    • 0037298005 scopus 로고    scopus 로고
    • Gastroprotective activity of < i > Nigella sativa oil and its constituent, thymoquinone, against gastric mucosal injury induced by ischaemia/reperfusion in rats
    • COI: 1:CAS:528:DC%2BD3sXhsleht74%3D, PID: 12648823
    • El-Abhar H, Abdallah D, Saleh S (2003) Gastroprotective activity of < i > Nigella sativa oil and its constituent, thymoquinone, against gastric mucosal injury induced by ischaemia/reperfusion in rats. J Ethnopharmacol 84:251–258
    • (2003) J Ethnopharmacol , vol.84 , pp. 251-258
    • El-Abhar, H.1    Abdallah, D.2    Saleh, S.3
  • 8
    • 84866457012 scopus 로고    scopus 로고
    • Attenuation of oxidative stress-induced vascular endothelial dysfunction by thymoquinone
    • COI: 1:CAS:528:DC%2BC38XhsFClsrnN
    • El-Agamy DS, Nader MA (2012) Attenuation of oxidative stress-induced vascular endothelial dysfunction by thymoquinone. Exp Biol Med 237:1032–1038
    • (2012) Exp Biol Med , vol.237 , pp. 1032-1038
    • El-Agamy, D.S.1    Nader, M.A.2
  • 9
    • 77954428874 scopus 로고    scopus 로고
    • Thymoquinone triggers anti-apoptotic signaling targeting death ligand and apoptotic regulators in a model of hepatic ischemia reperfusion injury
    • El-Ghany R, Sharaf N, Kassem L, Mahran L, Heikal O (2009) Thymoquinone triggers anti-apoptotic signaling targeting death ligand and apoptotic regulators in a model of hepatic ischemia reperfusion injury. Drug discoveries & therapeutics 3:296–306
    • (2009) Drug discoveries & therapeutics , vol.3 , pp. 296-306
    • El-Ghany, R.1    Sharaf, N.2    Kassem, L.3    Mahran, L.4    Heikal, O.5
  • 11
    • 33646202807 scopus 로고    scopus 로고
    • Thymoquinone: a promising anti-cancer drug from natural sources
    • COI: 1:CAS:528:DC%2BD28XksVGgsro%3D, PID: 16314136
    • Gali-Muhtasib H, Roessner A, Schneider-Stock R (2006) Thymoquinone: a promising anti-cancer drug from natural sources. Int J Biochem Cell Biol 38:1249–1253
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 1249-1253
    • Gali-Muhtasib, H.1    Roessner, A.2    Schneider-Stock, R.3
  • 12
    • 84884247190 scopus 로고    scopus 로고
    • Evaluation of protective effect of N-acetyl cysteine on arsenic-induced hepatotoxicity
    • PID: 24082739
    • Hemalatha P, Reddy AG, Reddy YR, Shivakumar P (2013) Evaluation of protective effect of N-acetyl cysteine on arsenic-induced hepatotoxicity. J Nat Sci Biol Med 4:393–395. doi:10.4103/0976-9668.116986
    • (2013) J Nat Sci Biol Med , vol.4 , pp. 393-395
    • Hemalatha, P.1    Reddy, A.G.2    Reddy, Y.R.3    Shivakumar, P.4
  • 13
    • 27944450775 scopus 로고    scopus 로고
    • NOSTRIN functions as a homotrimeric adaptor protein facilitating internalization of eNOS
    • COI: 1:CAS:528:DC%2BD2MXht1ynsbbM, PID: 16234328
    • Icking A, Matt S, Opitz N, Wiesenthal A, Müller-Esterl W, Schilling K (2005) NOSTRIN functions as a homotrimeric adaptor protein facilitating internalization of eNOS. J Cell Sci 118:5059–5069
    • (2005) J Cell Sci , vol.118 , pp. 5059-5069
    • Icking, A.1    Matt, S.2    Opitz, N.3    Wiesenthal, A.4    Müller-Esterl, W.5    Schilling, K.6
  • 14
    • 0037229864 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning
    • COI: 1:CAS:528:DC%2BD3sXntVSgug%3D%3D, PID: 12488232
    • Jaeschke H (2003) Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning. Am J Physiol Gastrointest Liver Physiol 284:G15–G26. doi:10.1152/ajpgi.00342.2002
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284 , pp. G15-G26
    • Jaeschke, H.1
  • 17
    • 0018069570 scopus 로고
    • Determination of malonaldehyde precursor in tissues by thiobarbituric acid test
    • Mihara M, Uchiyama M (1978) Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 86(1):271-8
    • (1978) Anal Biochem , vol.86 , Issue.1 , pp. 271-278
    • Mihara, M.1    Uchiyama, M.2
  • 18
    • 0035709008 scopus 로고    scopus 로고
    • A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite
    • Miranda KM, Espey MG, Wink DA (2001) A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide 5(1):62-71
    • (2001) Nitric Oxide , vol.5 , Issue.1 , pp. 62-71
    • Miranda, K.M.1    Espey, M.G.2    Wink, D.A.3
  • 21
    • 0033836675 scopus 로고    scopus 로고
    • Protective effect of thymoquinone against doxorubicin–induced cardiotoxicity in rats: a possible mechanism of protection
    • COI: 1:CAS:528:DC%2BD3cXhtFWjs78%3D, PID: 10675279
    • NAGI MN, MANSOUR MA (2000) Protective effect of thymoquinone against doxorubicin–induced cardiotoxicity in rats: a possible mechanism of protection. Pharmacol Res 41:283–289
    • (2000) Pharmacol Res , vol.41 , pp. 283-289
    • Nagi, M.N.1    Mansour, M.A.2
  • 22
    • 84878527645 scopus 로고    scopus 로고
    • The effects of curcumin on the liver and remote organs after hepatic ischemia reperfusion injury formed with Pringle manoeuvre in rats
    • COI: 1:STN:280:DC%2BC3svktVymtA%3D%3D, PID: 23467943
    • Oguz A et al (2013) The effects of curcumin on the liver and remote organs after hepatic ischemia reperfusion injury formed with Pringle manoeuvre in rats. Eur Rev Med Pharmacol Sci 17:457–466
    • (2013) Eur Rev Med Pharmacol Sci , vol.17 , pp. 457-466
    • Oguz, A.1
  • 23
    • 0018651356 scopus 로고
    • Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning
    • COI: 1:CAS:528:DyaL3cXht1ejs7k%3D, PID: 519312
    • Prescott L, Illingworth R, Critchley J, Stewart M, Adam R, Proudfoot A (1979) Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning. BMJ 2:1097–1100
    • (1979) BMJ , vol.2 , pp. 1097-1100
    • Prescott, L.1    Illingworth, R.2    Critchley, J.3    Stewart, M.4    Adam, R.5    Proudfoot, A.6
  • 24
    • 33748295539 scopus 로고    scopus 로고
    • Translocation of endothelial nitric-oxide synthase involves a ternary complex with caveolin-1 and NOSTRIN
    • COI: 1:CAS:528:DC%2BD28Xpt1alu74%3D, PID: 16807357
    • Schilling K, Opitz N, Wiesenthal A, Oess S, Tikkanen R, Muller-Esterl W, Icking A (2006) Translocation of endothelial nitric-oxide synthase involves a ternary complex with caveolin-1 and NOSTRIN. Mol Biol Cell 17:3870–3880. doi:10.1091/mbc.E05-08-0709
    • (2006) Mol Biol Cell , vol.17 , pp. 3870-3880
    • Schilling, K.1    Opitz, N.2    Wiesenthal, A.3    Oess, S.4    Tikkanen, R.5    Muller-Esterl, W.6    Icking, A.7
  • 25
    • 0037414397 scopus 로고    scopus 로고
    • Melatonin and N-acetylcysteine have beneficial effects during hepatic ischemia and reperfusion
    • Sener G, Tosun O, Sehirli AO, Kaçmaz A, Arbak S, Ersoy Y, Ayanoğlu-Dülger G (2003) Melatonin and N-acetylcysteine have beneficial effects during hepatic ischemia and reperfusion. Life Sci 72(24):2707-2718
    • (2003) Life Sci , vol.72 , Issue.24 , pp. 2707-2718
    • Sener, G.1    Tosun, O.2    Sehirli, A.O.3    Kaçmaz, A.4    Arbak, S.5    Ersoy, Y.6    Ayanoğlu-Dülger, G.7
  • 27
    • 0037234802 scopus 로고    scopus 로고
    • Nitric oxide in liver transplantation: pathobiology and clinical implications
    • PID: 12514766
    • Shah V, Kamath PS (2003) Nitric oxide in liver transplantation: pathobiology and clinical implications. Liver Transpl 9:1–11
    • (2003) Liver Transpl , vol.9 , pp. 1-11
    • Shah, V.1    Kamath, P.S.2
  • 28
    • 0031608982 scopus 로고    scopus 로고
    • The efficacy of N-acetylcysteine as a hepatoprotective agent in liver transplantation
    • PID: 9665023
    • Thies J et al (1998) The efficacy of N-acetylcysteine as a hepatoprotective agent in liver transplantation. Transpl Int 11:S390–S392
    • (1998) Transpl Int , vol.11 , pp. S390-S392
    • Thies, J.1
  • 29
    • 33644836737 scopus 로고    scopus 로고
    • Nitric oxide, a biological double-faced janus—is this good or bad?
    • Thippeswamy T, McKay JS, Quinn JP, Morris R (2006) Nitric oxide, a biological double-faced janus—is this good or bad? Histol Histopathol 21(4):445–458
    • (2006) Histol Histopathol , vol.21 , Issue.4 , pp. 445-458
    • Thippeswamy, T.1    McKay, J.S.2    Quinn, J.P.3    Morris, R.4
  • 30
    • 77953302292 scopus 로고    scopus 로고
    • Effect of simvastatin on nitric oxide synthases (eNOS, iNOS) and arginine and its derivatives (ADMA, SDMA) in ischemia/reperfusion injury in rat liver
    • COI: 1:CAS:528:DC%2BC3cXhtVGks77L, PID: 20508290
    • Trocha M, Merwid-Lad A, Szuba A, Chlebda E, Piesniewska M, Sozanski T, Szelag A (2010) Effect of simvastatin on nitric oxide synthases (eNOS, iNOS) and arginine and its derivatives (ADMA, SDMA) in ischemia/reperfusion injury in rat liver. Pharmacological reports: PR 62:343–351
    • (2010) Pharmacological reports: PR , vol.62 , pp. 343-351
    • Trocha, M.1    Merwid-Lad, A.2    Szuba, A.3    Chlebda, E.4    Piesniewska, M.5    Sozanski, T.6    Szelag, A.7
  • 31
    • 33749992417 scopus 로고    scopus 로고
    • N-acetylcysteine attenuates TNF-α-induced human vascular endothelial cell apoptosis and restores eNOS expression
    • COI: 1:CAS:528:DC%2BD28XhtFSksbbE, PID: 17026986
    • Xia Z, Liu M, Wu Y, Sharma V, Luo T, Ouyang J, McNeill JH (2006) N-acetylcysteine attenuates TNF-α-induced human vascular endothelial cell apoptosis and restores eNOS expression. Eur J Pharmacol 550:134–142
    • (2006) Eur J Pharmacol , vol.550 , pp. 134-142
    • Xia, Z.1    Liu, M.2    Wu, Y.3    Sharma, V.4    Luo, T.5    Ouyang, J.6    McNeill, J.H.7
  • 32
    • 58149240377 scopus 로고    scopus 로고
    • Nigella sativa relieves the deleterious effects of ischemia reperfusion injury on liver
    • PID: 18777598
    • Yildiz F et al (2008) Nigella sativa relieves the deleterious effects of ischemia reperfusion injury on liver. World journal of gastroenterology: WJG 14:5204
    • (2008) World journal of gastroenterology: WJG , vol.14 , pp. 5204
    • Yildiz, F.1
  • 33
    • 0037278466 scopus 로고    scopus 로고
    • Molecular mechanisms of N-acetylcysteine actions
    • COI: 1:CAS:528:DC%2BD3sXhvF2jsbc%3D, PID: 12613655
    • Zafarullah M, Li WQ, Sylvester J, Ahmad M (2003) Molecular mechanisms of N-acetylcysteine actions. Cell Mol Life Sci 60:6–20
    • (2003) Cell Mol Life Sci , vol.60 , pp. 6-20
    • Zafarullah, M.1    Li, W.Q.2    Sylvester, J.3    Ahmad, M.4
  • 34
    • 0028354118 scopus 로고
    • Mechanisms of reperfusion injury
    • Zimmerman BJ, Granger DN (1994) Mechanisms of reperfusion injury. Am J Med Sci 307(4):284-292
    • (1994) Am J Med Sci , vol.307 , Issue.4 , pp. 284-292
    • Zimmerman, B.J.1    Granger, D.N.2
  • 35
    • 0037168547 scopus 로고    scopus 로고
    • NOSTRIN: a protein modulating nitric oxide release and subcellular distribution of endothelial nitric oxide synthase
    • COI: 1:CAS:528:DC%2BD3sXhvV2qsw%3D%3D, PID: 12446846
    • Zimmermann K, Opitz N, Dedio J, Renne C, Muller-Esterl W, Oess S (2002) NOSTRIN: a protein modulating nitric oxide release and subcellular distribution of endothelial nitric oxide synthase. Proc Natl Acad Sci U S A 99:17167–17172. doi:10.1073/pnas.252345399
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 17167-17172
    • Zimmermann, K.1    Opitz, N.2    Dedio, J.3    Renne, C.4    Muller-Esterl, W.5    Oess, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.