SIRT1 attenuates high glucose-induced insulin resistance via reducing mitochondrial dysfunction in skeletal muscle cells

Experimental Biology and Medicine

Volumn 240, Issue 5, 2015, Pages 557-565

  Zhang, Hao Hao ^a   Ma, Xiao Jun ^a   Wu, Li Na ^a   Zhao, Yan Yan ^a   Zhang, Peng Yu ^a   Zhang, Ying Hui ^a   Shao, Ming Wei ^a   Liu, Fei ^a   Li, Fei ^b   Qin, Gui Jun ^a  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^b Division of Vasculitis Guancheng Traditional Chinese Medical Hospital   (China)

Author keywords

high glucose; Insulin resistance; mitochondrial dysfunction; silent information regulator 1; skeletal muscle cells

Indexed keywords

CITRATE SYNTHASE; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; SILENT INFORMATION REGULATOR PROTEIN; SILENT INFORMATION REGULATOR PROTEIN 1; SILENT INFORMATION REGULATOR PROTEIN 3; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; GLUCOSE; PRIMER DNA; SIRT1 PROTEIN, MOUSE; SIRTUIN 1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC TRANSFECTION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; INSULIN RESISTANCE; INSULIN SENSITIVITY; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; SPECTROPHOTOMETRY; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; CYTOLOGY; MUSCLE MITOCHONDRION; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PHYSIOLOGY;

MAMMALIA;

ANIMALS; BASE SEQUENCE; CELL LINE; DNA PRIMERS; GLUCOSE; INSULIN RESISTANCE; MICE; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; REAL-TIME POLYMERASE CHAIN REACTION; SIRTUIN 1;

EID: 84930441234     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370214557218     Document Type: Article

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